Jeff Sekelsky, PhD - Publications

Affiliations: 
1999- Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
recombination, DNA repair, meiosis
Website:
http://sekelsky.bio.unc.edu

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hatkevich T, Miller DE, Turcotte CA, Miller MC, Sekelsky J. A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks. Nucleic Acids Research. PMID 33406239 DOI: 10.1093/nar/gkaa1205  1
2020 Carvajal-Garcia J, Cho JE, Carvajal-Garcia P, Feng W, Wood RD, Sekelsky J, Gupta GP, Roberts SA, Ramsden DA. Mechanistic basis for microhomology identification and genome scarring by polymerase theta. Proceedings of the National Academy of Sciences of the United States of America. PMID 32234782 DOI: 10.1073/pnas.1921791117  1
2020 Carvajal-Garcia J, Gales ER, Ramsden DA, Sekelsky J. The Ortholog of RFWD3 Functions Independently of RAD51 During DNA Repair. G3 (Bethesda, Md.). PMID 31900333 DOI: 10.1534/g3.119.400903  1
2019 Hatkevich T, Boudreau V, Rubin T, Maddox PS, Huynh JR, Sekelsky J. Centromeric SMC1 promotes centromer clustering and stabilizes meiotic homolog pairing. Plos Genetics. 15: e1008412. PMID 31609962 DOI: 10.1371/journal.pgen.1008412  1
2019 Hartmann M, Umbanhowar J, Sekelsky J. Centromere-Proximal Meiotic Crossovers in Are Suppressed by Both Highly-Repetitive Heterochromatin and Proximity to the Centromere. Genetics. PMID 31345993 DOI: 10.1534/genetics.119.302509  0.52
2019 Hartmann M, Kohl KP, Sekelsky J, Hatkevich T. Meiotic MCM Proteins Promote and Inhibit Crossovers During Meiotic Recombination. Genetics. PMID 31028111 DOI: 10.1534/genetics.119.302221  1
2018 Crown KN, Miller DE, Sekelsky J, Hawley RS. Local Inversion Heterozygosity Alters Recombination throughout the Genome. Current Biology : Cb. PMID 30174188 DOI: 10.1016/j.cub.2018.07.004  1
2017 Brady MM, McMahan S, Sekelsky J. Loss of Drosophila Mei-41 / ATR Alters Meiotic Crossover Patterning. Genetics. PMID 29247012 DOI: 10.1534/genetics.117.300634  1
2017 Hatkevich T, Sekelsky J. Bloom syndrome helicase in meiosis: Pro-crossover functions of an anti-crossover protein. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 28792069 DOI: 10.1002/bies.201700073  1
2017 Hartmann MA, Sekelsky J. Chromosome 4 in Drosophila melanogaster: Imperfection or Interesting Exception? Fly. 0. PMID 28426351 DOI: 10.1080/19336934.2017.1321181  1
2017 Bellendir SP, Rognstad DJ, Morris LP, Zapotoczny G, Walton WG, Redinbo MR, Ramsden DA, Sekelsky J, Erie DA. Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates. Nucleic Acids Research. PMID 28369583 DOI: 10.1093/nar/gkx214  1
2017 Zapotoczny G, Sekelsky J. Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing Over During Double-Strand Break Repair. G3 (Bethesda, Md.). PMID 28179392 DOI: 10.1534/g3.116.037390  1
2016 Hatkevich T, Kohl KP, McMahan S, Hartmann MA, Williams AM, Sekelsky J. Bloom Syndrome Helicase Promotes Meiotic Crossover Patterning and Homolog Disjunction. Current Biology : Cb. PMID 27989672 DOI: 10.1016/j.cub.2016.10.055  1
2016 Romero NE, Matson SW, Sekelsky J. Biochemical Activities and Genetic Functions of the Drosophila melanogaster Fancm Helicase in DNA Repair. Genetics. PMID 27466228 DOI: 10.1534/genetics.116.192534  1
2014 Kuo HK, McMahan S, Rota CM, Kohl KP, Sekelsky J. Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases. Genetics. 198: 935-45. PMID 25205745 DOI: 10.1534/genetics.114.168096  1
2014 Crown KN, McMahan S, Sekelsky J. Eliminating both canonical and short-patch mismatch repair in Drosophila melanogaster suggests a new meiotic recombination model. Plos Genetics. 10: e1004583. PMID 25188408 DOI: 10.1371/journal.pgen.1004583  1
2014 LaFave MC, Andersen SL, Stoffregen EP, Holsclaw JK, Kohl KP, Overton LJ, Sekelsky J. Sources and structures of mitotic crossovers that arise when BLM helicase is absent in Drosophila. Genetics. 196: 107-18. PMID 24172129 DOI: 10.1534/genetics.113.158618  1
2013 Bellendir SP, Sekelsky J. An elegans Solution for Crossover Formation. Plos Genetics. 9: e1003658. PMID 23874241 DOI: 10.1371/journal.pgen.1003658  1
2013 Lake CM, Holsclaw JK, Bellendir SP, Sekelsky J, Hawley RS. The development of a monoclonal antibody recognizing the Drosophila melanogaster phosphorylated histone H2A variant (γ-H2AV). G3 (Bethesda, Md.). 3: 1539-43. PMID 23833215 DOI: 10.1534/g3.113.006833  1
2013 McMahan S, Kohl KP, Sekelsky J. Variation in meiotic recombination frequencies between allelic transgenes inserted at different sites in the Drosophila melanogaster genome. G3 (Bethesda, Md.). 3: 1419-27. PMID 23797104 DOI: 10.1534/g3.113.006411  1
2013 Kohl KP, Sekelsky J. Meiotic and mitotic recombination in meiosis. Genetics. 194: 327-34. PMID 23733849 DOI: 10.1534/genetics.113.150581  1
2013 Crown KN, Sekelsky J. Targeted gene replacement in Drosophila goes the distance. Genetics. 193: 377-81. PMID 23396476 DOI: 10.1534/genetics.112.148379  1
2012 Kohl KP, Jones CD, Sekelsky J. Evolution of an MCM complex in flies that promotes meiotic crossovers by blocking BLM helicase. Science (New York, N.Y.). 338: 1363-5. PMID 23224558 DOI: 10.1126/science.1228190  1
2011 Andersen SL, Kuo HK, Savukoski D, Brodsky MH, Sekelsky J. Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila. Plos Genetics. 7: e1002315. PMID 22022278 DOI: 10.1371/journal.pgen.1002315  1
2011 LaFave MC, Sekelsky J. Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster. Genetics. 188: 749-52. PMID 21527778 DOI: 10.1534/genetics.111.129825  1
2010 Andersen SL, Sekelsky J. Meiotic versus mitotic recombination: two different routes for double-strand break repair: the different functions of meiotic versus mitotic DSB repair are reflected in different pathway usage and different outcomes. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 1058-66. PMID 20967781 DOI: 10.1002/bies.201000087  1
2009 Andersen SL, Bergstralh DT, Kohl KP, LaRocque JR, Moore CB, Sekelsky J. Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination. Molecular Cell. 35: 128-35. PMID 19595722 DOI: 10.1016/j.molcel.2009.06.019  1
2009 Mukherjee S, LaFave MC, Sekelsky J. DNA damage responses in Drosophila nbs mutants with reduced or altered NBS function. Dna Repair. 8: 803-12. PMID 19395318 DOI: 10.1016/j.dnarep.2009.03.004  1
2009 LaFave MC, Sekelsky J. Mitotic recombination: why? when? how? where? Plos Genetics. 5: e1000411. PMID 19282976 DOI: 10.1371/journal.pgen.1000411  1
2008 Sekelsky J. The 2008 Genetics Society of America Award for Excellence in Education. R. Scott Hawley. Genetics. 178: 1131-3. PMID 18385106 DOI: 10.1534/genetics.104.017835  1
2008 Bergstralh DT, Sekelsky J. Interstrand crosslink repair: can XPF-ERCC1 be let off the hook? Trends in Genetics : Tig. 24: 70-6. PMID 18192062 DOI: 10.1016/j.tig.2007.11.003  1
2007 Trowbridge K, McKim K, Brill SJ, Sekelsky J. Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis. Genetics. 176: 1993-2001. PMID 17603121 DOI: 10.1534/genetics.106.070060  1
2007 McVey M, Andersen SL, Broze Y, Sekelsky J. Multiple functions of Drosophila BLM helicase in maintenance of genome stability. Genetics. 176: 1979-92. PMID 17507683 DOI: 10.1534/genetics.106.070052  1
2007 LaRocque JR, Dougherty DL, Hussain SK, Sekelsky J. Reducing DNA polymerase alpha in the absence of Drosophila ATR leads to P53-dependent apoptosis and developmental defects. Genetics. 176: 1441-51. PMID 17483406 DOI: 10.1534/genetics.107.073635  1
2007 Radford SJ, Sabourin MM, McMahan S, Sekelsky J. Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tracts. Genetics. 176: 53-62. PMID 17339220 DOI: 10.1534/genetics.107.070367  1
2007 Radford SJ, McMahan S, Blanton HL, Sekelsky J. Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutants. Genetics. 176: 63-72. PMID 17339219 DOI: 10.1534/genetics.107.070557  1
2007 LaRocque JR, Jaklevic B, Su TT, Sekelsky J. Drosophila ATR in double-strand break repair. Genetics. 175: 1023-33. PMID 17194776 DOI: 10.1534/genetics.106.067330  1
2005 Blanton HL, Radford SJ, McMahan S, Kearney HM, Ibrahim JG, Sekelsky J. REC, Drosophila MCM8, drives formation of meiotic crossovers. Plos Genetics. 1: e40. PMID 16189551 DOI: 10.1371/journal.pgen.0010040  1
2005 Radford SJ, Goley E, Baxter K, McMahan S, Sekelsky J. Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers. Genetics. 170: 1737-45. PMID 15944364 DOI: 10.1534/genetics.104.036178  1
2004 McVey M, Radut D, Sekelsky JJ. End-joining repair of double-strand breaks in Drosophila melanogaster is largely DNA ligase IV independent. Genetics. 168: 2067-76. PMID 15611176 DOI: 10.1534/genetics.104.033902  1
2004 McVey M, Larocque JR, Adams MD, Sekelsky JJ. Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion. Proceedings of the National Academy of Sciences of the United States of America. 101: 15694-9. PMID 15501916 DOI: 10.1073/pnas.0406157101  1
2004 Blanton H, Sekelsky J. Unique invasions and resolutions: DNA repair proteins in meiotic recombination in Drosophila melanogaster. Cytogenetic and Genome Research. 107: 172-9. PMID 15467362 DOI: 10.1159/000080595  1
2004 McVey M, Adams M, Staeva-Vieira E, Sekelsky JJ. Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila. Genetics. 167: 699-705. PMID 15238522 DOI: 10.1534/genetics.103.025411  1
2004 Yildiz O, Kearney H, Kramer BC, Sekelsky JJ. Mutational analysis of the Drosophila DNA repair and recombination gene mei-9. Genetics. 167: 263-73. PMID 15166153 DOI: 10.1534/genetics.167.1.263  1
2004 Radford SJ, Sekelsky JJ. Taking Drosophila Rad51 for a SPiN. Nature Structural & Molecular Biology. 11: 9-10. PMID 14718915 DOI: 10.1038/nsmb0104-9  1
2003 Laurençon A, Purdy A, Sekelsky J, Hawley RS, Su TT. Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR. Genetics. 164: 589-601. PMID 12807779  1
2003 Adams MD, McVey M, Sekelsky JJ. Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing. Science (New York, N.Y.). 299: 265-7. PMID 12522255 DOI: 10.1126/science.1077198  1
2002 Yildiz O, Majumder S, Kramer B, Sekelsky JJ. Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers. Molecular Cell. 10: 1503-9. PMID 12504024 DOI: 10.1016/S1097-2765(02)00782-7  1
2002 Adams MD, Sekelsky JJ. From sequence to phenotype: reverse genetics in Drosophila melanogaster. Nature Reviews. Genetics. 3: 189-98. PMID 11972156 DOI: 10.1038/nrg752  1
2001 Ozsoy AZ, Sekelsky JJ, Matson SW. Biochemical characterization of the small isoform of Drosophila melanogaster RECQ5 helicase. Nucleic Acids Research. 29: 2986-93. PMID 11452023  1
2000 Tisa LS, Sekelsky JJ, Adler J. Effects of organic antagonists of Ca(2+), Na(+), and K(+) on chemotaxis and motility of escherichia coli. Journal of Bacteriology. 182: 4856-61. PMID 10940028 DOI: 10.1128/JB.182.17.4856-4861.2000  1
2000 Sekelsky JJ, Brodsky MH, Burtis KC. DNA repair in Drosophila: insights from the Drosophila genome sequence. The Journal of Cell Biology. 150: F31-6. PMID 10908583 DOI: 10.1083/JCB.150.2.F31  1
2000 McKim KS, Jang JK, Sekelsky JJ, Laurencon A, Hawley RS. mei-41 is required for precocious anaphase in Drosophila females. Chromosoma. 109: 44-9. PMID 10855494 DOI: 10.1007/s004120050411  1
2000 Sekelsky JJ, Hollis KJ, Eimerl AI, Burtis KC, Hawley RS. Nucleotide excision repair endonuclease genes in Drosophila melanogaster. Mutation Research. 459: 219-28. PMID 10812334 DOI: 10.1016/S0921-8777(99)00075-0  1
2000 Brodsky MH, Sekelsky JJ, Tsang G, Hawley RS, Rubin GM. mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development. Genes & Development. 14: 666-78. PMID 10733527  1
1999 Sekelsky JJ, Brodsky MH, Rubin GM, Hawley RS. Drosophila and human RecQ5 exist in different isoforms generated by alternative splicing. Nucleic Acids Research. 27: 3762-9. PMID 10471747 DOI: 10.1093/nar/27.18.3762  1
1999 Sekelsky JJ, McKim KS, Messina L, French RL, Hurley WD, Arbel T, Chin GM, Deneen B, Force SJ, Hari KL, Jang JK, Laurençon AC, Madden LD, Matthies HJ, Milliken DB, et al. Identification of novel Drosophila meiotic genes recovered in a P-element screen. Genetics. 152: 529-42. PMID 10353897  1
1998 Sekelsky JJ, Burtis KC, Hawley RS. Damage control: the pleiotropy of DNA repair genes in Drosophila melanogaster. Genetics. 148: 1587-98. PMID 9560378  1
1998 McKim KS, Green-Marroquin BL, Sekelsky JJ, Chin G, Steinberg C, Khodosh R, Hawley RS. Meiotic synapsis in the absence of recombination. Science (New York, N.Y.). 279: 876-8. PMID 9452390 DOI: 10.1126/science.279.5352.876  1
1995 Sekelsky JJ, McKim KS, Chin GM, Hawley RS. The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1. Genetics. 141: 619-27. PMID 8647398  1
1995 Sekelsky JJ, Newfeld SJ, Raftery LA, Chartoff EH, Gelbart WM. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics. 139: 1347-58. PMID 7768443  1
1995 Sanicola M, Sekelsky J, Elson S, Gelbart WM. Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed. Genetics. 139: 745-56. PMID 7713429  1
1995 Hari KL, Santerre A, Sekelsky JJ, McKim KS, Boyd JB, Hawley RS. The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell. 82: 815-21. PMID 7671309 DOI: 10.1016/0092-8674(95)90478-6  1
1995 Sekelsky JJ, Hawley RS. The bond between sisters. Cell. 83: 157-60. PMID 7585932 DOI: 10.1016/0092-8674(95)90156-6  1
1988 Sager BM, Sekelsky JJ, Matsumura P, Adler J. Use of a computer to assay motility in bacteria. Analytical Biochemistry. 173: 271-7. PMID 3056105 DOI: 10.1016/0003-2697(88)90189-3  1
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