| Year |
Citation |
Score |
| 2024 |
Tiwari M, Gas-Pascual E, Goyal M, Popov M, Matsumoto K, Grafe M, Graf R, Haltiwanger RS, Olszewski N, Orlando R, Samuelson J, West CM. Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants. Biorxiv : the Preprint Server For Biology. PMID 39464065 DOI: 10.1101/2024.10.15.618526 |
0.471 |
|
| 2024 |
Matsumoto K, Luther KB, Haltiwanger RS. Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development. Glycobiology. PMID 38976017 DOI: 10.1093/glycob/cwae047 |
0.418 |
|
| 2024 |
Neupane S, Williamson DB, Roth RA, Halabi CM, Haltiwanger RS, Holdener BC. Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues. The Journal of Biological Chemistry. 107445. PMID 38844137 DOI: 10.1016/j.jbc.2024.107445 |
0.391 |
|
| 2024 |
Houlahan CB, Kong Y, Johnston B, Cielesh M, Chau TH, Fenwick J, Coleman PR, Hao H, Haltiwanger RS, Thaysen-Andersen M, Passam FH, Larance M. Analysis of the healthy platelet proteome identifies a new form of domain-specific O-fucosylation. Molecular & Cellular Proteomics : McP. 100717. PMID 38237698 DOI: 10.1016/j.mcpro.2024.100717 |
0.306 |
|
| 2023 |
LoPilato RK, Kroeger H, Mohan SK, Lauderdale JD, Grimsey N, Haltiwanger RS. Two NOTCH1 O-fucose sites have opposing functions in mouse retinal angiogenesis. Glycobiology. PMID 37329502 DOI: 10.1093/glycob/cwad048 |
0.36 |
|
| 2023 |
Berardinelli SJ, Sillato AR, Grady RC, Neupane S, Ito A, Haltiwanger RS, Holdener BC. O-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules. Glycobiology. PMID 36721988 DOI: 10.1093/glycob/cwad006 |
0.417 |
|
| 2022 |
Grennell JA, Jenkins KD, Luther KB, Glushka J, Haltiwanger RS, Macnaughtan MA. H, N, C backbone and sidechain resonance assignments and secondary structure of mouse NOTCH1 EGF27. Biomolecular Nmr Assignments. PMID 36565355 DOI: 10.1007/s12104-022-10116-0 |
0.36 |
|
| 2022 |
Pennarubia F, Ito A, Takeuchi M, Haltiwanger RS. Cancer-associated Notch receptor variants lead to O-fucosylation defects that deregulate Notch signaling. The Journal of Biological Chemistry. 102616. PMID 36265581 DOI: 10.1016/j.jbc.2022.102616 |
0.446 |
|
| 2022 |
Matsumoto K, Kumar V, Varshney S, Nairn AV, Ito A, Pennarubia F, Moremen KW, Stanley P, Haltiwanger RS. Fringe GlcNAc-transferases differentially extend O-fucose on endogenous NOTCH1 in mouse activated T cells. The Journal of Biological Chemistry. 102064. PMID 35623385 DOI: 10.1016/j.jbc.2022.102064 |
0.459 |
|
| 2022 |
Berardinelli SJ, Eletsky A, Valero-González J, Ito A, Manjunath R, Hurtado-Guerrero R, Prestegard JR, Woods RJ, Haltiwanger RS. O-Fucosylation stabilizes the TSR3 motif in Thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond. The Journal of Biological Chemistry. 102047. PMID 35597280 DOI: 10.1016/j.jbc.2022.102047 |
0.452 |
|
| 2022 |
Williamson DB, Haltiwanger RS. Identification, function, and biological relevance of POGLUT2 and POGLUT3. Biochemical Society Transactions. PMID 35411374 DOI: 10.1042/BST20210850 |
0.519 |
|
| 2022 |
Neupane S, Berardinelli SJ, Cameron DC, Grady RC, Komatsu DE, Percival CJ, Takeuchi M, Ito A, Liu TW, Nairn AV, Moremen KW, Haltiwanger RS, Holdener BC. O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 35167946 DOI: 10.1016/j.matbio.2022.02.002 |
0.425 |
|
| 2021 |
Williamson DB, Sohn CJ, Ito A, Haltiwanger RS. POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of FBN1. The Journal of Biological Chemistry. 101055. PMID 34411563 DOI: 10.1016/j.jbc.2021.101055 |
0.468 |
|
| 2021 |
Zhang A, Venkat A, Taujale R, Mull JL, Ito A, Kannan N, Haltiwanger RS. Peters plus syndrome mutations affect the function and stability of human β1,3-glucosyltransferase. The Journal of Biological Chemistry. 100843. PMID 34058199 DOI: 10.1016/j.jbc.2021.100843 |
0.306 |
|
| 2020 |
Yu S, Wang W, Albakri M, Yu X, Majihail G, Lim S, Lopilato RK, Ito A, Letterio J, Haltiwanger RS, Zhou L. O-Fucose and Fringe-modified NOTCH1 Extracellular Domain Fragments as Decoys to Release Niche-lodged Hematopoietic Progenitor Cells. Glycobiology. PMID 33351914 DOI: 10.1093/glycob/cwaa113 |
0.395 |
|
| 2020 |
Matsumoto K, Luther KB, Haltiwanger RS. Diseases related to Notch glycosylation. Molecular Aspects of Medicine. 100938. PMID 33341260 DOI: 10.1016/j.mam.2020.100938 |
0.418 |
|
| 2020 |
Zhang A, Berardinelli SJ, Leonhard-Melief C, Vasudevan D, Liu TW, Taibi A, Giannone S, Apte SS, Holdener BC, Haltiwanger RS. -Fucosylation of ADAMTSL2 is required for secretion and is impacted by geleophysic dysplasia-causing mutations. The Journal of Biological Chemistry. PMID 32913123 DOI: 10.1074/Jbc.Ra120.014557 |
0.357 |
|
| 2020 |
Ma C, Takeuchi H, Hao H, Yonekawa C, Nakajima K, Nagae M, Okajima T, Haltiwanger RS, Kizuka Y. Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs. International Journal of Molecular Sciences. 21. PMID 32825463 DOI: 10.3390/Ijms21176007 |
0.408 |
|
| 2020 |
Kakuda S, Lopilato RK, Ito A, Haltiwanger RS. Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2. The Journal of Biological Chemistry. PMID 32820046 DOI: 10.1074/Jbc.Ra120.014407 |
0.336 |
|
| 2020 |
Grennell JA, Jenkins KD, Zhong H, Paudyal A, Luther KB, Haltiwanger RS, Macnaughtan MA. Expression, purification, and glycosylation of epidermal growth factor-like repeat 27 from mouse NOTCH1. Protein Expression and Purification. 105681. PMID 32505675 DOI: 10.1016/J.Pep.2020.105681 |
0.497 |
|
| 2020 |
Servián-Morilla E, Cabrera-Serrano M, Johnson K, Pandey A, Ito A, Rivas E, Chamova T, Muelas N, Mongini T, Nafissi S, Claeys KG, Grewal RP, Takeuchi M, Hao H, Bönnemann C, ... ... Haltiwanger RS, et al. POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern. Acta Neuropathologica. PMID 31897643 DOI: 10.1007/S00401-019-02117-6 |
0.334 |
|
| 2020 |
Berardinelli SJ, Haltiwanger RS. Analyzing the Effects of O-Fucosylation on Secretion of ADAMTS Proteins Using Cell-Based Assays. Methods in Molecular Biology (Clifton, N.J.). 2043: 25-43. PMID 31463900 DOI: 10.1007/978-1-4939-9698-8_3 |
0.531 |
|
| 2020 |
Berardinelli SJ, Manjunath R, Eletsky A, Ito A, Haltiwanger RS. How Do O ‐Fucose Glycans Stabilize Thrombospondin Type 1 Repeats? The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05437 |
0.484 |
|
| 2019 |
Pandey A, Harvey BM, Lopez MF, Ito A, Haltiwanger RS, Jafar-Nejad H. Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila. Cell Reports. 29: 2054-2066.e6. PMID 31722217 DOI: 10.1016/J.Celrep.2019.10.027 |
0.539 |
|
| 2019 |
Moremen KW, Haltiwanger RS. Emerging structural insights into glycosyltransferase-mediated synthesis of glycans. Nature Chemical Biology. 15: 853-864. PMID 31427814 DOI: 10.1038/S41589-019-0350-2 |
0.363 |
|
| 2019 |
Mendoza JL, Escalante NK, Jude KM, Sotolongo Bellon J, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC. Structure of the IFNγ receptor complex guides design of biased agonists. Nature. PMID 30814731 DOI: 10.1038/S41586-019-0988-7 |
0.304 |
|
| 2019 |
Holdener BC, Haltiwanger RS. Protein O-fucosylation: structure and function. Current Opinion in Structural Biology. 56: 78-86. PMID 30690220 DOI: 10.1016/J.Sbi.2018.12.005 |
0.591 |
|
| 2018 |
Takeuchi H, Schneider M, Williamson DB, Ito A, Takeuchi M, Handford PA, Haltiwanger RS. Two novel protein -glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30127001 DOI: 10.1073/Pnas.1804005115 |
0.427 |
|
| 2018 |
Harvey BM, Haltiwanger RS. Regulation of Notch Function by O-Glycosylation. Advances in Experimental Medicine and Biology. 1066: 59-78. PMID 30030822 DOI: 10.1007/978-3-319-89512-3_4 |
0.564 |
|
| 2018 |
Takeuchi H, Wong D, Schneider M, Freeze HH, Takeuchi M, Berardinelli SJ, Ito A, Lee H, Nelson SF, Haltiwanger RS. Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features. Glycobiology. PMID 29452367 DOI: 10.1093/Glycob/Cwy014 |
0.427 |
|
| 2018 |
Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS. Inhibition of Delta-induced Notch signaling using fucose analogs. Nature Chemical Biology. 14: 65-71. PMID 29176671 DOI: 10.1038/Nchembio.2520 |
0.474 |
|
| 2018 |
Matsumoto K, Haltiwanger RS. What are the Real Functions of O-Glycan Modifications of Notch? Trends in Glycoscience and Glycotechnology. 30: E129-E136. DOI: 10.4052/Tigg.1720.4E |
0.511 |
|
| 2017 |
Weh E, Takeuchi H, Muheisen S, Haltiwanger RS, Semina EV. Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome. Plos One. 12: e0184903. PMID 28926587 DOI: 10.1371/Journal.Pone.0184903 |
0.396 |
|
| 2017 |
Takeuchi H, Yu H, Hao H, Takeuchi M, Ito A, Li H, Haltiwanger RS. O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking. The Journal of Biological Chemistry. PMID 28729422 DOI: 10.1074/Jbc.M117.800102 |
0.568 |
|
| 2017 |
Schneider M, Al-Shareffi E, Haltiwanger RS. Biological functions of fucose in mammals. Glycobiology. PMID 28430973 DOI: 10.1093/Glycob/Cwx034 |
0.708 |
|
| 2017 |
Luca VC, Kim BC, Ge C, Kakuda S, Wu D, Roein-Peikar M, Haltiwanger RS, Zhu C, Ha T, Garcia KC. Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity. Science (New York, N.Y.). PMID 28254785 DOI: 10.1126/Science.Aaf9739 |
0.357 |
|
| 2017 |
Hubmacher D, Schneider M, Berardinelli SJ, Takeuchi H, Willard B, Reinhardt DP, Haltiwanger RS, Apte SS. Unusual life cycle and impact on microfibril assembly of ADAMTS17, a secreted metalloprotease mutated in genetic eye disease. Scientific Reports. 7: 41871. PMID 28176809 DOI: 10.1038/Srep41871 |
0.357 |
|
| 2016 |
Kakuda S, Haltiwanger RS. Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands. Developmental Cell. PMID 28089369 DOI: 10.1016/J.Devcel.2016.12.013 |
0.386 |
|
| 2016 |
Servián-Morilla E, Takeuchi H, Lee TV, Clarimon J, Mavillard F, Area-Gómez E, Rivas E, Nieto-González JL, Rivero MC, Cabrera-Serrano M, Gómez-Sánchez L, Martínez-López JA, Estrada B, Márquez C, Morgado Y, ... ... Haltiwanger RS, et al. A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss. Embo Molecular Medicine. 8: 1289-1309. PMID 27807076 DOI: 10.15252/Emmm.201505815 |
0.348 |
|
| 2016 |
Dubail J, Vasudevan D, Wang LW, Earp SE, Jenkins MW, Haltiwanger RS, Apte SS. Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome. Scientific Reports. 6: 33974. PMID 27687499 DOI: 10.1038/Srep33974 |
0.414 |
|
| 2016 |
Yu H, Takeuchi H, Takeuchi M, Liu Q, Kantharia J, Haltiwanger RS, Li H. Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations. Nature Chemical Biology. PMID 27428513 DOI: 10.1038/Nchembio.2135 |
0.421 |
|
| 2016 |
Benz BA, Nandadasa S, Takeuchi M, Grady RC, Takeuchi H, LoPilato RK, Kakuda S, Somerville RP, Apte SS, Haltiwanger RS, Holdener BC. Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion. Developmental Biology. PMID 27297885 DOI: 10.1016/J.Ydbio.2016.05.038 |
0.496 |
|
| 2016 |
Harvey BM, Rana NA, Moss H, Leonardi J, Jafar-Nejad H, Haltiwanger RS. Mapping sites of O-glycosylation and fringe elongation on Drosophila Notch. The Journal of Biological Chemistry. PMID 27268051 DOI: 10.1074/Jbc.M116.732537 |
0.541 |
|
| 2016 |
Valero-González J, Leonhard-Melief C, Lira-Navarrete E, Jiménez-Osés G, Hernández-Ruiz C, Pallarés MC, Yruela I, Vasudevan D, Lostao A, Corzana F, Takeuchi H, Haltiwanger RS, Hurtado-Guerrero R. A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2. Nature Chemical Biology. PMID 26854667 DOI: 10.1038/Nchembio.2019 |
0.425 |
|
| 2016 |
Valero-Gonzalez J, Leonhard-Melief C, Lira-Navarrete E, Jimenez-Oses G, Hernandez-Ruiz C, Pallares MC, Yruela I, Vasudevan D, Lostao A, Corzana F, Takeuchi H, Haltiwanger RS, Hurtado-Guerrero R. A Proactive Role of Water Molecules in Acceptor Recognition of Thrombospondin Type 1 Repeats by Protein-O-Fucosyltransferase 2 Nature Chemical Biology. 12: 240. DOI: 10.2210/Pdb5Foe/Pdb |
0.465 |
|
| 2015 |
Feizi TE, Haltiwanger RS. Editorial overview: Carbohydrate-protein interactions and glycosylation: Glycan synthesis and recognition: finding the perfect partner in a sugar-coated life. Current Opinion in Structural Biology. 34: vii-ix. PMID 26613983 DOI: 10.1016/J.Sbi.2015.10.005 |
0.4 |
|
| 2015 |
Hart GW, Schnaar RL, Haltiwanger RS. A Quarter Century of Glycobiology. Glycobiology. 25: 1321-2. PMID 26543185 DOI: 10.1093/Glycob/Cwv090 |
0.495 |
|
| 2015 |
Ramkumar N, Harvey BM, Lee JD, Alcorn HL, Silva-Gagliardi NF, McGlade CJ, Bestor TH, Wijnholds J, Haltiwanger RS, Anderson KV. Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2. Plos Genetics. 11: e1005551. PMID 26496195 DOI: 10.1371/Journal.Pgen.1005551 |
0.532 |
|
| 2015 |
Yu H, Takeuchi M, LeBarron J, Kantharia J, London E, Bakker H, Haltiwanger RS, Li H, Takeuchi H. Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. Nature Chemical Biology. PMID 26414444 DOI: 10.1038/Nchembio.1927 |
0.331 |
|
| 2015 |
Vasudevan D, Takeuchi H, Johar SS, Majerus E, Haltiwanger RS. Peters plus syndrome mutations disrupt a noncanonical ER quality-control mechanism. Current Biology : Cb. 25: 286-95. PMID 25544610 DOI: 10.1016/J.Cub.2014.11.049 |
0.454 |
|
| 2014 |
Haltom AR, Lee TV, Harvey BM, Leonardi J, Chen YJ, Hong Y, Haltiwanger RS, Jafar-Nejad H. The protein O-glucosyltransferase Rumi modifies eyes shut to promote rhabdomere separation in Drosophila. Plos Genetics. 10: e1004795. PMID 25412384 DOI: 10.1371/Journal.Pgen.1004795 |
0.494 |
|
| 2014 |
Vasudevan D, Haltiwanger RS. Novel roles for O-linked glycans in protein folding. Glycoconjugate Journal. 31: 417-26. PMID 25186198 DOI: 10.1007/S10719-014-9556-4 |
0.549 |
|
| 2014 |
Kakuda S, Haltiwanger RS. Analyzing the posttranslational modification status of Notch using mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1187: 209-21. PMID 25053492 DOI: 10.1007/978-1-4939-1139-4_16 |
0.533 |
|
| 2014 |
Takeuchi H, Haltiwanger RS. Significance of glycosylation in Notch signaling. Biochemical and Biophysical Research Communications. 453: 235-42. PMID 24909690 DOI: 10.1016/J.Bbrc.2014.05.115 |
0.535 |
|
| 2014 |
Taylor P, Takeuchi H, Sheppard D, Chillakuri C, Lea SM, Haltiwanger RS, Handford PA. Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands. Proceedings of the National Academy of Sciences of the United States of America. 111: 7290-5. PMID 24803430 DOI: 10.1073/Pnas.1319683111 |
0.446 |
|
| 2014 |
Müller J, Rana NA, Serth K, Kakuda S, Haltiwanger RS, Gossler A. O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function. Plos One. 9: e88571. PMID 24533113 DOI: 10.1371/Journal.Pone.0088571 |
0.52 |
|
| 2014 |
Haltom AR, Lee TV, Harvey BM, Leonardi J, Chen Y, Hong Y, Haltiwanger RS, Jafar-Nejad H. Loss of O -glucose on Notch cannot explain the rumi −/− rhabdomere attachment phenotype. Plos Genetics. DOI: 10.1371/Journal.Pgen.1004795.G002 |
0.39 |
|
| 2013 |
Takeuchi H, Haltiwanger RS. Enzymatic analysis of the protein O-glycosyltransferase, Rumi, acting toward epidermal growth factor-like (EGF) repeats. Methods in Molecular Biology (Clifton, N.J.). 1022: 119-28. PMID 23765658 DOI: 10.1007/978-1-62703-465-4_10 |
0.574 |
|
| 2013 |
Lee TV, Sethi MK, Leonardi J, Rana NA, Buettner FF, Haltiwanger RS, Bakker H, Jafar-Nejad H. Negative regulation of notch signaling by xylose. Plos Genetics. 9: e1003547. PMID 23754965 DOI: 10.1371/Journal.Pgen.1003547 |
0.53 |
|
| 2013 |
Al-Shareffi E, Chaubard JL, Leonhard-Melief C, Wang SK, Wong CH, Haltiwanger RS. 6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin type-1 repeats by protein O-fucosyltransferases 1 and 2. Glycobiology. 23: 188-98. PMID 23045360 DOI: 10.1093/Glycob/Cws140 |
0.746 |
|
| 2012 |
Yamamoto S, Charng WL, Rana NA, Kakuda S, Jaiswal M, Bayat V, Xiong B, Zhang K, Sandoval H, David G, Wang H, Haltiwanger RS, Bellen HJ. A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands. Science (New York, N.Y.). 338: 1229-32. PMID 23197537 DOI: 10.1126/Science.1228745 |
0.337 |
|
| 2012 |
Takeuchi H, Kantharia J, Sethi MK, Bakker H, Haltiwanger RS. Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of individual EGF repeats. The Journal of Biological Chemistry. 287: 33934-44. PMID 22872643 DOI: 10.1074/Jbc.M112.401315 |
0.536 |
|
| 2012 |
Sethi MK, Buettner FF, Ashikov A, Krylov VB, Takeuchi H, Nifantiev NE, Haltiwanger RS, Gerardy-Schahn R, Bakker H. Molecular cloning of a xylosyltransferase that transfers the second xylose to O-glucosylated epidermal growth factor repeats of notch. The Journal of Biological Chemistry. 287: 2739-48. PMID 22117070 DOI: 10.1074/Jbc.M111.302406 |
0.535 |
|
| 2011 |
Takeuchi H, Fernández-Valdivia RC, Caswell DS, Nita-Lazar A, Rana NA, Garner TP, Weldeghiorghis TK, Macnaughtan MA, Jafar-Nejad H, Haltiwanger RS. Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 108: 16600-5. PMID 21949356 DOI: 10.1073/Pnas.1109696108 |
0.546 |
|
| 2011 |
Rana NA, Haltiwanger RS. Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors. Current Opinion in Structural Biology. 21: 583-9. PMID 21924891 DOI: 10.1016/J.Sbi.2011.08.008 |
0.503 |
|
| 2011 |
Rana NA, Nita-Lazar A, Takeuchi H, Kakuda S, Luther KB, Haltiwanger RS. O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1. The Journal of Biological Chemistry. 286: 31623-37. PMID 21757702 DOI: 10.1074/Jbc.M111.268243 |
0.496 |
|
| 2011 |
Fernandez-Valdivia R, Takeuchi H, Samarghandi A, Lopez M, Leonardi J, Haltiwanger RS, Jafar-Nejad H. Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi. Development (Cambridge, England). 138: 1925-34. PMID 21490058 DOI: 10.1242/Dev.060020 |
0.54 |
|
| 2010 |
Leonhard-Melief C, Haltiwanger RS. O-fucosylation of thrombospondin type 1 repeats. Methods in Enzymology. 480: 401-16. PMID 20816219 DOI: 10.1016/S0076-6879(10)80018-7 |
0.54 |
|
| 2010 |
Du J, Takeuchi H, Leonhard-Melief C, Shroyer KR, Dlugosz M, Haltiwanger RS, Holdener BC. O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. Developmental Biology. 346: 25-38. PMID 20637190 DOI: 10.1016/J.Ydbio.2010.07.008 |
0.507 |
|
| 2010 |
Takeuchi H, Haltiwanger RS. Role of glycosylation of Notch in development. Seminars in Cell & Developmental Biology. 21: 638-45. PMID 20226260 DOI: 10.1016/J.Semcdb.2010.03.003 |
0.378 |
|
| 2010 |
Sethi MK, Buettner FF, Krylov VB, Takeuchi H, Nifantiev NE, Haltiwanger RS, Gerardy-Schahn R, Bakker H. Identification of glycosyltransferase 8 family members as xylosyltransferases acting on O-glucosylated notch epidermal growth factor repeats. The Journal of Biological Chemistry. 285: 1582-6. PMID 19940119 DOI: 10.1074/Jbc.C109.065409 |
0.506 |
|
| 2009 |
Wang LW, Leonhard-Melief C, Haltiwanger RS, Apte SS. Post-translational modification of thrombospondin type-1 repeats in ADAMTS-like 1/punctin-1 by C-mannosylation of tryptophan. The Journal of Biological Chemistry. 284: 30004-15. PMID 19671700 DOI: 10.1074/Jbc.M109.038059 |
0.36 |
|
| 2009 |
Haltiwanger RS. Fucose is on the TRAIL of colon cancer. Gastroenterology. 137: 36-9. PMID 19482107 DOI: 10.1053/J.Gastro.2009.05.010 |
0.536 |
|
| 2009 |
Bakker H, Oka T, Ashikov A, Yadav A, Berger M, Rana NA, Bai X, Jigami Y, Haltiwanger RS, Esko JD, Gerardy-Schahn R. Functional UDP-xylose transport across the endoplasmic reticulum/Golgi membrane in a Chinese hamster ovary cell mutant defective in UDP-xylose Synthase. The Journal of Biological Chemistry. 284: 2576-83. PMID 19028698 DOI: 10.1074/Jbc.M804394200 |
0.394 |
|
| 2009 |
Luther KB, Schindelin H, Haltiwanger RS. Structural and mechanistic insights into lunatic fringe from a kinetic analysis of enzyme mutants. The Journal of Biological Chemistry. 284: 3294-305. PMID 19028689 DOI: 10.1074/Jbc.M805502200 |
0.482 |
|
| 2009 |
Luther KB, Haltiwanger RS. Role of unusual O-glycans in intercellular signaling. The International Journal of Biochemistry & Cell Biology. 41: 1011-24. PMID 18952191 DOI: 10.1016/J.Biocel.2008.10.001 |
0.542 |
|
| 2008 |
Haltiwanger RS. Unsweetened Notch leads to myeloproliferation. Blood. 112: 214-5. PMID 18606881 DOI: 10.1182/Blood-2008-04-150391 |
0.56 |
|
| 2008 |
Acar M, Jafar-Nejad H, Takeuchi H, Rajan A, Ibrani D, Rana NA, Pan H, Haltiwanger RS, Bellen HJ. Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling. Cell. 132: 247-58. PMID 18243100 DOI: 10.1016/J.Cell.2007.12.016 |
0.421 |
|
| 2008 |
Takeuchi H, Haltiwanger RS. The role of O-glucosylation in notch signaling Trends in Glycoscience and Glycotechnology. 20: 159-170. DOI: 10.4052/tigg.20.159 |
0.446 |
|
| 2008 |
Du J, Takeuchi H, Leonhard C, Dlugosz M, Haltiwanger RS, Holdener BC. O-Fucose modification is essential for patterning mesoderm in the mouse embryo Developmental Biology. 319: 586. DOI: 10.1016/J.Ydbio.2008.05.422 |
0.464 |
|
| 2007 |
Xu A, Haines N, Dlugosz M, Rana NA, Takeuchi H, Haltiwanger RS, Irvine KD. In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe. The Journal of Biological Chemistry. 282: 35153-62. PMID 17923477 DOI: 10.1074/Jbc.M707040200 |
0.391 |
|
| 2007 |
Rampal R, Luther KB, Haltiwanger RS. Notch signaling in normal and disease States: possible therapies related to glycosylation. Current Molecular Medicine. 7: 427-45. PMID 17584081 DOI: 10.2174/156652407780831593 |
0.707 |
|
| 2007 |
Shi S, Ge C, Luo Y, Hou X, Haltiwanger RS, Stanley P. The threonine that carries fucose, but not fucose, is required for Cripto to facilitate Nodal signaling. The Journal of Biological Chemistry. 282: 20133-41. PMID 17504756 DOI: 10.1074/Jbc.M702593200 |
0.572 |
|
| 2007 |
Ricketts LM, Dlugosz M, Luther KB, Haltiwanger RS, Majerus EM. O-fucosylation is required for ADAMTS13 secretion. The Journal of Biological Chemistry. 282: 17014-23. PMID 17395589 DOI: 10.1074/Jbc.M700317200 |
0.508 |
|
| 2007 |
Wang LW, Dlugosz M, Somerville RP, Raed M, Haltiwanger RS, Apte SS. O-fucosylation of thrombospondin type 1 repeats in ADAMTS-like-1/punctin-1 regulates secretion: implications for the ADAMTS superfamily. The Journal of Biological Chemistry. 282: 17024-31. PMID 17395588 DOI: 10.1074/Jbc.M701065200 |
0.538 |
|
| 2006 |
Nita-Lazar A, Haltiwanger RS. Methods for analysis of O-linked modifications on epidermal growth factor-like and thrombospondin type 1 repeats. Methods in Enzymology. 417: 93-111. PMID 17132500 DOI: 10.1016/S0076-6879(06)17008-1 |
0.516 |
|
| 2006 |
Nita-Lazar A, Haltiwanger RS. Methods for analysis of unusual forms of O-glycosylation. Methods in Molecular Biology (Clifton, N.J.). 347: 57-68. PMID 17072004 DOI: 10.1385/1-59745-167-3:57 |
0.522 |
|
| 2006 |
Kozma K, Keusch JJ, Hegemann B, Luther KB, Klein D, Hess D, Haltiwanger RS, Hofsteenge J. Identification and characterization of abeta1,3-glucosyltransferase that synthesizes the Glc-beta1,3-Fuc disaccharide on thrombospondin type 1 repeats. The Journal of Biological Chemistry. 281: 36742-51. PMID 17032646 DOI: 10.1074/Jbc.M605912200 |
0.448 |
|
| 2006 |
Loriol C, Dupuy F, Rampal R, Dlugosz MA, Haltiwanger RS, Maftah A, Germot A. Molecular evolution of protein O-fucosyltransferase genes and splice variants. Glycobiology. 16: 736-47. PMID 16679357 DOI: 10.1093/Glycob/Cwj124 |
0.66 |
|
| 2006 |
Luo Y, Nita-Lazar A, Haltiwanger RS. Two distinct pathways for O-fucosylation of epidermal growth factor-like or thrombospondin type 1 repeats. The Journal of Biological Chemistry. 281: 9385-92. PMID 16464858 DOI: 10.1074/Jbc.M511974200 |
0.578 |
|
| 2006 |
Luo Y, Koles K, Vorndam W, Haltiwanger RS, Panin VM. Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats. The Journal of Biological Chemistry. 281: 9393-9. PMID 16464857 DOI: 10.1074/Jbc.M511975200 |
0.565 |
|
| 2005 |
Rampal R, Li AS, Moloney DJ, Georgiou SA, Luther KB, Nita-Lazar A, Haltiwanger RS. Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats. The Journal of Biological Chemistry. 280: 42454-63. PMID 16221665 DOI: 10.1074/Jbc.M509552200 |
0.706 |
|
| 2005 |
Rampal R, Arboleda-Velasquez JF, Nita-Lazar A, Kosik KS, Haltiwanger RS. Highly conserved O-fucose sites have distinct effects on Notch1 function. The Journal of Biological Chemistry. 280: 32133-40. PMID 15994302 DOI: 10.1074/Jbc.M506104200 |
0.685 |
|
| 2005 |
Arboleda-Velasquez JF, Rampal R, Fung E, Darland DC, Liu M, Martinez MC, Donahue CP, Navarro-Gonzalez MF, Libby P, D'Amore PA, Aikawa M, Haltiwanger RS, Kosik KS. CADASIL mutations impair Notch3 glycosylation by Fringe. Human Molecular Genetics. 14: 1631-9. PMID 15857853 DOI: 10.1093/Hmg/Ddi171 |
0.654 |
|
| 2005 |
Luo Y, Haltiwanger RS. O-fucosylation of notch occurs in the endoplasmic reticulum. The Journal of Biological Chemistry. 280: 11289-94. PMID 15653671 DOI: 10.1074/Jbc.M414574200 |
0.575 |
|
| 2005 |
Li G, Yan Q, Nita-Lazar A, Haltiwanger RS, Lennarz WJ. Studies on the N-glycosylation of the subunits of oligosaccharyl transferase in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 280: 1864-71. PMID 15507441 DOI: 10.1074/Jbc.M410969200 |
0.541 |
|
| 2004 |
Haltiwanger RS, Lowe JB. Role of glycosylation in development. Annual Review of Biochemistry. 73: 491-537. PMID 15189151 DOI: 10.1146/Annurev.Biochem.73.011303.074043 |
0.481 |
|
| 2004 |
Haltiwanger RS. Regulation of signal transduction by glycosylation International Journal of Experimental Pathology. 85. DOI: 10.1111/J.0959-9673.2004.0390B.X |
0.591 |
|
| 2003 |
Hatsell S, Medina L, Merola J, Haltiwanger R, Cowin P. Plakoglobin is O-glycosylated close to the N-terminal destruction box. The Journal of Biological Chemistry. 278: 37745-52. PMID 12847106 DOI: 10.1074/Jbc.M301346200 |
0.401 |
|
| 2003 |
Sturla L, Rampal R, Haltiwanger RS, Fruscione F, Etzioni A, Tonetti M. Differential terminal fucosylation of N-linked glycans versus protein O-fucosylation in leukocyte adhesion deficiency type II (CDG IIc). The Journal of Biological Chemistry. 278: 26727-33. PMID 12738772 DOI: 10.1074/Jbc.M304068200 |
0.666 |
|
| 2003 |
Shao L, Haltiwanger RS. O-fucose modifications of epidermal growth factor-like repeats and thrombospondin type 1 repeats: unusual modifications in unusual places. Cellular and Molecular Life Sciences : Cmls. 60: 241-50. PMID 12678489 DOI: 10.1007/s000180300019 |
0.656 |
|
| 2002 |
Shao L, Moloney DJ, Haltiwanger R. Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region. The Journal of Biological Chemistry. 278: 7775-82. PMID 12486116 DOI: 10.1074/Jbc.M212221200 |
0.65 |
|
| 2002 |
Haltiwanger RS. Regulation of signal transduction pathways in development by glycosylation. Current Opinion in Structural Biology. 12: 593-8. PMID 12464310 DOI: 10.1016/S0959-440X(02)00371-8 |
0.422 |
|
| 2002 |
Shao L, Moloney DJ, Haltiwanger RS. O-glycosylation of EGF repeats: Identification and initial characterization of a UDP-glucose: Protein O-glucosyltransferase Glycobiology. 12: 763-770. PMID 12460944 DOI: 10.1093/Glycob/Cwf085 |
0.636 |
|
| 2002 |
Haltiwanger RS, Stanley P. Modulation of receptor signaling by glycosylation: fringe is an O-fucose-beta1,3-N-acetylglucosaminyltransferase. Biochimica Et Biophysica Acta. 1573: 328-35. PMID 12417415 DOI: 10.1016/S0304-4165(02)00400-2 |
0.484 |
|
| 2002 |
Yan YT, Liu JJ, Luo Y, E C, Haltiwanger RS, Abate-Shen C, Shen MM. Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway. Molecular and Cellular Biology. 22: 4439-49. PMID 12052855 DOI: 10.1128/Mcb.22.13.4439-4449.2002 |
0.402 |
|
| 2002 |
Panin VM, Shao L, Lei L, Moloney DJ, Irvine KD, Haltiwanger RS. Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe. The Journal of Biological Chemistry. 277: 29945-52. PMID 12036964 DOI: 10.1074/Jbc.M204445200 |
0.669 |
|
| 2001 |
Wang Y, Shao L, Shi S, Harris RJ, Spellman MW, Stanley P, Haltiwanger RS. Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase. The Journal of Biological Chemistry. 276: 40338-45. PMID 11524432 DOI: 10.1074/Jbc.M107849200 |
0.644 |
|
| 2001 |
Haltiwanger RS. Fringe : A Glycosyltransferase That Modulates Notch Signaling Trends in Glycoscience and Glycotechnology. 13: 157-165. DOI: 10.4052/Tigg.13.157 |
0.588 |
|
| 2000 |
Moloney DJ, Panin VM, Johnston SH, Chen J, Shao L, Wilson R, Wang Y, Stanley P, Irvine KD, Haltiwanger RS, Vogt TF. Fringe is a glycosyltransferase that modifies Notch. Nature. 406: 369-75. PMID 10935626 DOI: 10.1038/35019000 |
0.604 |
|
| 2000 |
Moloney DJ, Shair LH, Lu FM, Xia J, Locke R, Matta KL, Haltiwanger RS. Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules Journal of Biological Chemistry. 275: 9604-9611. PMID 10734111 DOI: 10.1074/Jbc.275.13.9604 |
0.562 |
|
| 1999 |
Moloney DJ, Haltiwanger RS. The O-linked fucose glycosylation pathway. Identification and characterization of a uridine diphosphoglucose: Fucose-β1,3-glucosyltransferase activity from Chinese hamster ovary cells Glycobiology. 9: 679-687. PMID 10362837 DOI: 10.1093/Glycob/9.7.679 |
0.497 |
|
| 1998 |
Medina L, Grove K, Haltiwanger RS. SV40 large T antigen is modified with O-linked N-acetylglucosamine but not with other forms of glycosylation Glycobiology. 8: 383-391. PMID 9499386 DOI: 10.1093/Glycob/8.4.383 |
0.45 |
|
| 1998 |
Haltiwanger RS, Grove K, Philipsberg GA. Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-β-N- acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D- glucopyranosylidene)amino-N-phenylcarbamate Journal of Biological Chemistry. 273: 3611-3617. PMID 9452489 DOI: 10.1074/Jbc.273.6.3611 |
0.552 |
|
| 1998 |
Medina L, Haltiwanger RS. Calf thymus high mobility group proteins are nonenzymatically glycated but not significantly glycosylated Glycobiology. 8: 191-198. PMID 9451029 DOI: 10.1093/Glycob/8.2.191 |
0.391 |
|
| 1998 |
Moloney DJ, Haltiwanger RS. Identification and characterization of an o-linked fucose-specific β 1,3-glucosyltransferase activity from chinese hamster ovary cells Faseb Journal. 12. |
0.387 |
|
| 1997 |
Moloney DJ, Lin AI, Haltiwanger RS. The O-linked fucose glycosylation pathway. Evidence for protein-specific elongation of o-linked fucose in Chinese hamster ovary cells. The Journal of Biological Chemistry. 272: 19046-50. PMID 9228088 DOI: 10.1074/Jbc.272.30.19046 |
0.585 |
|
| 1997 |
Haltiwanger RS, Philipsberg GA. Mitotic arrest with nocodazole induces selective changes in the level of O-linked n-acetylglucosamine and accumulation of incompletely processed N- glycans on proteins from HT29 cells Journal of Biological Chemistry. 272: 8752-8758. PMID 9079710 DOI: 10.1074/Jbc.272.13.8752 |
0.537 |
|
| 1997 |
Haltiwanger RS, Busby S, Grove K, Li S, Mason D, Medina L, Moloney D, Philipsberg G, Scartozzi R. O-glycosylation of nuclear and cytoplasmic proteins: Regulation analogous to phosphorylation? Biochemical and Biophysical Research Communications. 231: 237-242. PMID 9070256 DOI: 10.1006/Bbrc.1997.6110 |
0.501 |
|
| 1994 |
Lin AI, Philipsberg GA, Haltiwanger RS. Core fucosylation of high-mannose-type oligosaccharides in GlcNAc transferase I-deficient (Lec1) CHO cells. Glycobiology. 4: 895-901. PMID 7734851 DOI: 10.1093/Glycob/4.6.895 |
0.321 |
|
| 1993 |
Haltiwanger RS, Hart GW. Glycosyltransferases as tools in cell biological studies Methods in Molecular Biology (Clifton, N.J.). 14: 175-187. PMID 8348234 DOI: 10.1385/0-89603-226-4:175 |
0.488 |
|
| 1992 |
Reason AJ, Morris HR, Panico M, Marais R, Treisman RH, Haltiwanger RS, Hart GW, Kelly WG, Dell A. Localization of O-GlcNAc modification on the serum response transcription factor Journal of Biological Chemistry. 267: 16911-16921. PMID 1512232 |
0.359 |
|
| 1992 |
Haltiwanger RS, Kelly WG, Roquemore EP, Blomberg MA, Dong LYD, Kreppel L, Chou TY, Hart GW. Glycosylation of nuclear and cytoplasmic proteins is ubiquitous and dynamic Biochemical Society Transactions. 20: 264-269. PMID 1397609 DOI: 10.1042/Bst0200264 |
0.591 |
|
| 1991 |
Lüthi T, Haltiwanger RS, Greengard P, Bähler M. Synapsins contain O-linked N-acetylglucosamine. Journal of Neurochemistry. 56: 1493-8. PMID 1901592 DOI: 10.1111/J.1471-4159.1991.Tb02043.X |
0.388 |
|
| 1991 |
Reason AJ, Blench IP, Haltiwanger RS, Hart GW, Morris HR, Panico M, Dell A. High-sensitivity FAB-MS strategies for O-GlcNAc characterization Glycobiology. 1: 585-594. PMID 1822238 DOI: 10.1093/Glycob/1.6.585 |
0.613 |
|
| 1990 |
Haltiwanger RS, Holt GD, Hart GW. Enzymatic addition of O-G1cNAc to nuclear and cytoplasmic proteins: Identification of a uridine diphospho-N-acetylglucosamine:Peptide β-N-acetylglucosaminyltransferase Journal of Biological Chemistry. 265: 2563-2568. PMID 2137449 |
0.319 |
|
| 1990 |
Mullis KG, Haltiwanger RS, Hart GW, Marchase RB, Engler JA. Relative accessibility of N-acetylglucosamine in trimers of the adenovirus types 2 and 5 fiber proteins Journal of Virology. 64: 5317-5323. PMID 2120471 DOI: 10.1128/Jvi.64.11.5317-5323.1990 |
0.539 |
|
| 1990 |
Mullis KG, Haltiwanger RS, Hart GW, Marchase RB, Engler JA. Relative accessibility of N-acetylglucosamine in trimers of the adenovirus types 2 and 5 fiber proteins. Journal of Virology. 64: 5317-5323. DOI: 10.1128/jvi.64.11.5317-5323.1990 |
0.446 |
|
| 1989 |
Hart GW, Haltiwanger RS, Holt GD, Kelly WG. Glycosylation in the nucleus and cytoplasm Annual Review of Biochemistry. 58: 841-874. PMID 2673024 DOI: 10.1146/Annurev.Bi.58.070189.004205 |
0.536 |
|
| 1989 |
Whiteheart SW, Passaniti A, Reichner JS, Holt GD, Haltiwanger RS, Hart GW. Glycosyltransferase probes Methods in Enzymology. 179: 82-95. PMID 2516227 DOI: 10.1016/0076-6879(89)79116-3 |
0.659 |
|
| 1989 |
Hart GW, Haltiwanger RS, Holt GD, Kelly WG. Nucleoplasmic and cytoplasmic glycoproteins Ciba Foundation Symposium. 145: 102-112, discussion . PMID 2507249 DOI: 10.1002/9780470513828.ch7 |
0.662 |
|
| 1988 |
D'Onofrio M, Starr CM, Park MK, Holt GD, Haltiwanger RS, Hart GW, Hanover JA. Partial cDNA sequence encoding a nuclear pore protein modified by O-linked N-acetylglucosamine Proceedings of the National Academy of Sciences of the United States of America. 85: 9595-9599. PMID 3200844 DOI: 10.1073/Pnas.85.24.9595 |
0.556 |
|
| 1988 |
Hart GW, Holt GD, Haltiwanger RS. Nuclear and cytoplasmic glycosylation: novel saccharide linkages in unexpected places Trends in Biochemical Sciences. 13: 380-384. PMID 3072699 DOI: 10.1016/0968-0004(88)90179-X |
0.568 |
|
| 1988 |
Benko DM, Haltiwanger RS, Hart GW, Gibson W. Virion basic phosphoprotein from human cytomegalovirus contains O-linked N-acetylglucosamine Proceedings of the National Academy of Sciences of the United States of America. 85: 2573-2577. PMID 2833746 DOI: 10.1073/Pnas.85.8.2573 |
0.615 |
|
| 1987 |
Holt GD, Snow CM, Senior A, Haltiwanger RS, Gerace L, Hart GW. Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine Journal of Cell Biology. 104: 1157-1164. PMID 3571327 DOI: 10.1083/Jcb.104.5.1157 |
0.676 |
|
| 1987 |
Holt GD, Haltiwanger RS, Torres CR, Hart GW. Erythrocytes contain cytoplasmic glycoproteins. O-linked GlcNac on band 4.1 Journal of Biological Chemistry. 262: 14847-14850. PMID 3117790 |
0.456 |
|
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