| Year |
Citation |
Score |
| 2024 |
Wang P, Chen L, Mora-Cartin R, McIntosh CM, Sattar H, Chong AS, Alegre ML. Low Affinity CD8 T Cells Provide Interclonal Help to High Affinity CD8 T Cells to Augment Alloimmunity. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 38228228 DOI: 10.1016/j.ajt.2024.01.008 |
0.338 |
|
| 2023 |
McIntosh CM, Allocco JB, Wang P, McKeague ML, Cassano A, Wang Y, Xie SZ, Hynes GE, Mora-Cartín R, Abbondanza D, Chen L, Sattar H, Yin D, Zhang ZJ, Chong AS, ... Alegre ML, et al. Heterogeneity in allospecific T cell function in transplant tolerant hosts determines susceptibility to rejection following infection. The Journal of Clinical Investigation. PMID 37676735 DOI: 10.1172/JCI168465 |
0.418 |
|
| 2023 |
Chong A, Pollard J, Hynes G, Yin D, Mandal M, Gounari F, Alegre ML. Pregnancy programs epigenetic and transcriptional exhaustion in memory CD8+ T cells. Research Square. PMID 37066154 DOI: 10.21203/rs.3.rs-2196637/v1 |
0.302 |
|
| 2022 |
Gupta PK, Allocco JB, Fraipont JM, McKeague ML, Wang P, Andrade MS, McIntosh C, Chen L, Wang Y, Li Y, Andrade J, Conejo-Garcia JR, Chong AS, Alegre ML. Reduced Satb1 expression predisposes CD4 T conventional cells to Treg suppression and promotes transplant survival. Proceedings of the National Academy of Sciences of the United States of America. 119: e2205062119. PMID 36161903 DOI: 10.1073/pnas.2205062119 |
0.42 |
|
| 2022 |
Pirozzolo ID, Sepulveda M, Chen L, Wang Y, Lei YM, Li Z, Li R, Sattar H, Theriault BR, Belkaid Y, Chong AS, Alegre ML. Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants. The Journal of Clinical Investigation. PMID 35834335 DOI: 10.1172/JCI153403 |
0.301 |
|
| 2022 |
Andrade MS, Young JS, Pollard JM, Yin D, Alegre ML, Chong AS. Linked sensitization by memory CD4+ T cells prevents costimulation blockade-induced transplantation tolerance. Jci Insight. 7. PMID 35674134 DOI: 10.1172/jci.insight.159205 |
0.349 |
|
| 2022 |
Wang P, Chen L, McIntosh CM, Lane JI, Li R, Xie SZ, Sattar H, Esterhazy D, Chong AS, Alegre ML. Oral Alloantigen Exposure Promotes Donor-specific Tolerance in a Mouse Model of Minor-Mismatched Skin Transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 35633180 DOI: 10.1111/ajt.17107 |
0.317 |
|
| 2021 |
Chong AS, Sage PT, Alegre ML. Regulation of Alloantibody Responses. Frontiers in Cell and Developmental Biology. 9: 706171. PMID 34307385 DOI: 10.3389/fcell.2021.706171 |
0.371 |
|
| 2020 |
Cravedi P, Schold JD, Safa K, Kates OS, Elfadawy N, Mannon RB, Shah MB, Hammond SP, Avery R, Guerrero Miranda C, Riella LV, Jowsey-Gregoire S, Akalin E, Camirand G, Alegre ML, et al. The COVID-19 Pandemic: A community approach. Clinical Transplantation. e14059. PMID 32762055 DOI: 10.1111/Ctr.14059 |
0.322 |
|
| 2020 |
Alegre ML. Introduction to this Cellular Immunology issue on new advances in solid organ transplantation immunology. Cellular Immunology. 355: 104156. PMID 32619810 DOI: 10.1016/J.Cellimm.2020.104156 |
0.344 |
|
| 2020 |
Alegre ML. Can Diet Induce Transplantation Tolerance? Journal of the American Society of Nephrology : Jasn. PMID 32482687 DOI: 10.1681/Asn.2020050661 |
0.346 |
|
| 2020 |
Khiew SH, Jain D, Chen J, Yang J, Yin D, Young JS, Dent A, Sciammas R, Alegre ML, Chong AS. Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells. The Journal of Clinical Investigation. PMID 32452834 DOI: 10.1172/Jci132814 |
0.431 |
|
| 2020 |
Chong AS, Issa F, Leuvenink HGD, Alegre ML. The First ITS Meeting. Transplantation. 104: 1114-1116. PMID 32433230 DOI: 10.1097/Tp.0000000000003132 |
0.323 |
|
| 2020 |
Si Y, Zhao F, Beesetty P, Weiskopf D, Li Z, Tian Q, Alegre ML, Sette A, Chong AS, Montgomery CP. Inhibition of protective immunity against infection by MHC-restricted immunodominance is overcome by vaccination. Science Advances. 6: eaaw7713. PMID 32270029 DOI: 10.1126/Sciadv.Aaw7713 |
0.311 |
|
| 2020 |
Allocco JB, Alegre ML. Exploiting immunometabolism and T cell function for solid organ transplantation. Cellular Immunology. 104068. PMID 32139072 DOI: 10.1016/J.Cellimm.2020.104068 |
0.376 |
|
| 2020 |
Mcintosh CM, Alegre ML. Giving effector/memory T cells a new (suppressive) purpose. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 20: 625. PMID 32090473 DOI: 10.1111/Ajt.15804 |
0.337 |
|
| 2020 |
Allocco JB, Alegre ML. In vivo and in vitro differences in CD8 T cell metabolism. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 20: 327. PMID 31983082 DOI: 10.1111/Ajt.15781 |
0.403 |
|
| 2019 |
Piper C, Zhou V, Komorowski R, Szabo A, Vincent B, Serody J, Alegre ML, Edelson BT, Taneja R, Drobyski WR. Pathogenic Bhlhe40+ GM-CSF+ CD4+ T Cells Promote Indirect Alloantigen Presentation in the GI Tract during GVHD. Blood. PMID 31880771 DOI: 10.1182/Blood.2019001696 |
0.323 |
|
| 2019 |
Alegre ML. DeTOXifying exhausted T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 19: 2965. PMID 31742914 DOI: 10.1111/Ajt.15637 |
0.39 |
|
| 2019 |
Miller ML, McIntosh CM, Wang Y, Chen L, Wang P, Lei YM, Daniels MD, Watkins E, Mora Solano C, Chong AS, Alegre ML. Resilience of T cell-intrinsic dysfunction in transplantation tolerance. Proceedings of the National Academy of Sciences of the United States of America. PMID 31685610 DOI: 10.1073/Pnas.1910298116 |
0.469 |
|
| 2019 |
Sepulveda M, Pirozzolo I, Alegre ML. Impact of the microbiota on solid organ transplant rejection. Current Opinion in Organ Transplantation. PMID 31577594 DOI: 10.1097/Mot.0000000000000702 |
0.35 |
|
| 2019 |
Lei YM, Sepulveda M, Chen L, Wang Y, Pirozzolo I, Theriault B, Chong AS, Belkaid Y, Alegre ML. Skin-restricted commensal colonization accelerates skin graft rejection. Jci Insight. 5. PMID 31310590 DOI: 10.1172/Jci.Insight.127569 |
0.394 |
|
| 2019 |
Alegre ML. Neuroimmunology and the control of T cell migration. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 19: 1605. PMID 31136699 DOI: 10.1111/Ajt.15411 |
0.364 |
|
| 2019 |
Azzi J, Alegre ML. Outstanding Questions in Transplantation: an Introduction to this Minireview Series. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30903734 DOI: 10.1111/Ajt.15367 |
0.326 |
|
| 2019 |
Gupta PK, McIntosh CM, Chong AS, Alegre ML. The pursuit of transplantation tolerance: new mechanistic insights. Cellular & Molecular Immunology. PMID 30760917 DOI: 10.1038/S41423-019-0203-7 |
0.417 |
|
| 2019 |
Rael VE, Chen L, McIntosh CM, Alegre ML. Exercise increases skin graft resistance to rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30659772 DOI: 10.1111/Ajt.15266 |
0.371 |
|
| 2019 |
Alegre ML. B cells, CMV, and stem cell transplant. Science (New York, N.Y.). 363: 232-233. PMID 30655432 DOI: 10.1126/Science.Aav9867 |
0.377 |
|
| 2019 |
Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, ... ... Alegre ML, et al. Thymic regulatory T cells arise via two distinct developmental programs. Nature Immunology. PMID 30643267 DOI: 10.1038/S41590-018-0289-6 |
0.431 |
|
| 2018 |
Alegre ML. Danger, Metabolism and T Cell Memory. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18: 2375. PMID 30261133 DOI: 10.1111/Ajt.15092 |
0.315 |
|
| 2018 |
Miller ML, McIntosh CM, Williams JB, Wang Y, Hollinger MK, Isaad NJ, Moon JJ, Gajewski TF, Chong AS, Alegre ML. Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance. Cell Reports. 24: 2112-2126. PMID 30134172 DOI: 10.1016/J.Celrep.2018.07.067 |
0.484 |
|
| 2018 |
Mcintosh CM, Alegre ML. Metabolic Control of T Cell Memory. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18: 1835. PMID 30134007 DOI: 10.1111/Ajt.15001 |
0.312 |
|
| 2018 |
Young JS, Yin D, Vannier AGL, Alegre ML, Chong AS. Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and Tolerance. Frontiers in Immunology. 9: 1385. PMID 29973932 DOI: 10.3389/Fimmu.2018.01385 |
0.511 |
|
| 2018 |
McIntosh CM, Chen L, Shaiber A, Eren AM, Alegre ML. Gut microbes contribute to variation in solid organ transplant outcomes in mice. Microbiome. 6: 96. PMID 29793539 DOI: 10.1186/S40168-018-0474-8 |
0.38 |
|
| 2018 |
Tu E, Chia CPZ, Chen W, Zhang D, Park SA, Jin W, Wang D, Alegre ML, Zhang YE, Sun L, Chen W. T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation. Immunity. 48: 745-759.e6. PMID 29669252 DOI: 10.1016/J.Immuni.2018.03.025 |
0.373 |
|
| 2018 |
Alegre ML. Sweet T Cell Dysfunction. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18: 775. PMID 29603604 DOI: 10.1111/Ajt.14729 |
0.389 |
|
| 2018 |
Alegre ML. DC Metabolism Controls Lung T Cell Polarization. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18: 285. PMID 29381270 DOI: 10.1111/Ajt.14648 |
0.307 |
|
| 2018 |
Riella LV, Alegre ML. Novel Role of Calcineurin Inhibitors in Curbing T Cells' Sweet Tooth. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18: 3. PMID 29267999 DOI: 10.1111/Ajt.14606 |
0.368 |
|
| 2018 |
Alegre ML. What's new in transplantation tolerance? Current Opinion in Organ Transplantation. 23: 63-65. PMID 29189414 DOI: 10.1097/Mot.0000000000000493 |
0.342 |
|
| 2017 |
Miller ML, Chong AS, Alegre ML. Fifty Shades of Tolerance: Beyond a Binary Tolerant/Non-Tolerant Paradigm. Current Transplantation Reports. 4: 262-269. PMID 31098340 DOI: 10.1007/S40472-017-0166-5 |
0.367 |
|
| 2017 |
Young JS, Khiew SH, Yang J, Vannier A, Yin D, Sciammas R, Alegre ML, Chong AS. Successful Treatment of T Cell-Mediated Acute Rejection with Delayed CTLA4-Ig in Mice. Frontiers in Immunology. 8: 1169. PMID 28970838 DOI: 10.3389/fimmu.2017.01169 |
0.408 |
|
| 2017 |
Young JS, McIntosh C, Alegre ML, Chong AS. Evolving Approaches in the Identification of Allograft-reactive T and B Cells in Mice and Humans. Transplantation. PMID 28604446 DOI: 10.1097/Tp.0000000000001847 |
0.457 |
|
| 2017 |
Riella LV, Bagley J, Iacomini J, Alegre ML. Impact of environmental factors on alloimmunity and transplant fate. The Journal of Clinical Investigation. PMID 28481225 DOI: 10.1172/Jci90596 |
0.394 |
|
| 2017 |
Khiew SH, Yang J, Young JS, Chen J, Wang Q, Yin D, Vu V, Miller ML, Sciammas R, Alegre ML, Chong AS. CTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipients. Jci Insight. 2. PMID 28469082 DOI: 10.1172/jci.insight.92033 |
0.404 |
|
| 2017 |
Alegre ML. The Tpm Subset of the CD8(+) T Cell Memory Family. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 17: 849. PMID 28371536 DOI: 10.1111/Ajt.14243 |
0.363 |
|
| 2017 |
Suah AN, Young JS, Khiew SH, Wang Q, Yin D, Alegre M, Chong AS. Induction of Sensitization and Resistance to Transplant Tolerance by Allogeneic Pregnancy Transplantation. 101. DOI: 10.1097/01.Tp.0000520347.55444.0E |
0.311 |
|
| 2016 |
Alegre ML. Ionic Checkpoint: Potassium-Driven T Cell Immunosuppression. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 16: 3313. PMID 28267261 DOI: 10.1111/Ajt.14095 |
0.41 |
|
| 2016 |
Miller ML, Alegre ML, Chong AS. Transplantation tolerance after allograft rejection. Current Opinion in Organ Transplantation. PMID 27898463 DOI: 10.1097/Mot.0000000000000374 |
0.428 |
|
| 2016 |
Alegre ML, Lakkis FG, Morelli AE. Antigen Presentation in Transplantation. Trends in Immunology. PMID 27743777 DOI: 10.1016/j.it.2016.09.003 |
0.345 |
|
| 2016 |
Lei YM, Chen L, Wang Y, Stefka AT, Molinero LL, Theriault B, Aquino-Michaels K, Sivan AS, Nagler CR, Gajewski TF, Chong AS, Bartman C, Alegre ML. The composition of the microbiota modulates allograft rejection. The Journal of Clinical Investigation. PMID 27322054 DOI: 10.1172/Jci85295 |
0.453 |
|
| 2016 |
Arina A, Idel C, Hyjek EM, Alegre ML, Wang Y, Bindokas VP, Weichselbaum RR, Schreiber H. Tumor-associated fibroblasts predominantly come from local and not circulating precursors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27317748 DOI: 10.1073/Pnas.1600363113 |
0.308 |
|
| 2016 |
Young JS, Daniels MD, Miller ML, Wang T, Zhong R, Yin D, Alegre ML, Chong AS. Erosion of Transplantation Tolerance after Infection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27273890 DOI: 10.1111/Ajt.13910 |
0.342 |
|
| 2016 |
Miller ML, Daniels MD, Wang T, Wang Y, Xu J, Yin D, Chong AS, Alegre ML. Tracking of TCR-Tg T cells reveals multiple mechanisms maintain cardiac transplant tolerance in mice. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27091509 DOI: 10.1111/Ajt.13814 |
0.452 |
|
| 2016 |
Miller ML, Chen J, Daniels MD, McKeague MG, Wang Y, Yin D, Vu V, Chong AS, Alegre ML. Adoptive transfer of tracer alloreactive CD4(+) TCR-transgenic T cells alters the endogenous immune response to an allograft. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27063351 DOI: 10.1111/Ajt.13821 |
0.493 |
|
| 2016 |
Molinero LL, Yin D, Lei K, Chen L, Wang Y, Chong AS, Alegre ML. High-Fat Diet-Induced Obesity Enhances Allograft Rejection. Transplantation. PMID 27007226 DOI: 10.1097/Tp.0000000000001141 |
0.301 |
|
| 2016 |
Young JS, Chen J, Miller ML, Vu V, Tian C, Moon JJ, Alegre ML, Sciammas R, Chong AS. Delayed CTLA4-Ig treatment reverses ongoing alloantibody responses and rescues allografts from acute rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26928966 DOI: 10.1111/Ajt.13761 |
0.489 |
|
| 2016 |
Evaristo C, Spranger S, Barnes SE, Miller ML, Molinero LL, Locke FL, Gajewski TF, Alegre ML. Cutting Edge: Engineering Active IKKβ in T Cells Drives Tumor Rejection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26903482 DOI: 10.4049/Jimmunol.1501144 |
0.392 |
|
| 2015 |
Theriault B, Wang Y, Chen L, Vest A, Bartman C, Alegre ML. Long-term Maintenance of Sterility Following Skin Transplantation in Germ-free Mice. Transplantation Direct. 1. PMID 26609546 DOI: 10.1097/Txd.0000000000000539 |
0.333 |
|
| 2015 |
Sivan A, Corrales L, Hubert N, Williams JB, Aquino-Michaels K, Earley ZM, Benyamin FW, Man Lei Y, Jabri B, Alegre ML, Chang EB, Gajewski TF. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science (New York, N.Y.). PMID 26541606 DOI: 10.1126/Science.Aac4255 |
0.366 |
|
| 2015 |
Zhao F, Cheng BL, Boyle-Vavra S, Alegre ML, Daum RS, Chong AS, Montgomery CP. Proteomic Identification of saeRS-Dependent Targets Critical for Protective Humoral Immunity against Staphylococcus aureus Skin Infection. Infection and Immunity. 83: 3712-21. PMID 26169277 DOI: 10.1128/Iai.00667-15 |
0.304 |
|
| 2015 |
Miller ML, Daniels MD, Wang T, Chen J, Young J, Xu J, Wang Y, Yin D, Vu V, Husain AN, Alegre ML, Chong AS. Spontaneous restoration of transplantation tolerance after acute rejection. Nature Communications. 6: 7566. PMID 26151823 DOI: 10.1038/Ncomms8566 |
0.394 |
|
| 2015 |
Xu Y, Evaristo C, Alegre ML, Gurbuxani S, Kee BL. Analysis of GzmbCre as a Model System for Gene Deletion in the Natural Killer Cell Lineage. Plos One. 10: e0125211. PMID 25923440 DOI: 10.1371/Journal.Pone.0125211 |
0.604 |
|
| 2015 |
Barnes SE, Wang Y, Chen L, Molinero LL, Gajewski TF, Evaristo C, Alegre ML. T cell-NF-κB activation is required for tumor control in vivo. Journal For Immunotherapy of Cancer. 3: 1. PMID 25648675 DOI: 10.1186/S40425-014-0045-X |
0.399 |
|
| 2015 |
Alegre ML. I spy alloreactive T cells. Science Translational Medicine. 7: 272fs3. PMID 25632032 DOI: 10.1126/Scitranslmed.Aaa5083 |
0.433 |
|
| 2015 |
Bartman C, Chong AS, Alegre ML. The influence of the microbiota on the immune response to transplantation. Current Opinion in Organ Transplantation. 20: 1-7. PMID 25563985 DOI: 10.1097/Mot.0000000000000150 |
0.363 |
|
| 2014 |
Alegre ML, Mannon RB, Mannon PJ. The microbiota, the immune system and the allograft. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 1236-48. PMID 24840316 DOI: 10.1111/Ajt.12760 |
0.357 |
|
| 2014 |
Miller ML, Mashayekhi M, Chen L, Zhou P, Liu X, Michelotti M, Tramontini Gunn N, Powers S, Zhu X, Evaristo C, Alegre ML, Molinero LL. Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 7397-402. PMID 24799710 DOI: 10.1073/Pnas.1315398111 |
0.313 |
|
| 2014 |
Montgomery CP, Daniels M, Zhao F, Alegre ML, Chong AS, Daum RS. Protective immunity against recurrent Staphylococcus aureus skin infection requires antibody and interleukin-17A. Infection and Immunity. 82: 2125-34. PMID 24614654 DOI: 10.1128/Iai.01491-14 |
0.353 |
|
| 2014 |
Chong AS, Alegre ML. Transplantation tolerance and its outcome during infections and inflammation. Immunological Reviews. 258: 80-101. PMID 24517427 DOI: 10.1111/Imr.12147 |
0.458 |
|
| 2014 |
Alegre ML, Bartman C, Chong AS. Microbes and allogeneic transplantation. Transplantation. 97: 5-11. PMID 23903013 DOI: 10.1097/Tp.0B013E3182A2037F |
0.379 |
|
| 2014 |
Poroyko V, Semenyuk E, Xu Z, Sperling A, Alegre M, Chong A, Garrity E, White S, Bhorade S. Post-Transplant Dynamics of Pulmonary Microbiota Annals of the American Thoracic Society. 11: S74-S74. DOI: 10.1513/Annalsats.201307-238Mg |
0.58 |
|
| 2013 |
Chong AS, Alegre ML, Miller ML, Fairchild RL. Lessons and limits of mouse models. Cold Spring Harbor Perspectives in Medicine. 3: a015495. PMID 24296351 DOI: 10.1101/cshperspect.a015495 |
0.341 |
|
| 2013 |
Evaristo C, Alegre ML. IFN-γ: The Dr. Jekyll and Mr. Hyde of immunology? American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 3057-8. PMID 24148260 DOI: 10.1111/Ajt.12468 |
0.483 |
|
| 2012 |
Molinero LL, Cubre A, Mora-Solano C, Wang Y, Alegre ML. T cell receptor/CARMA1/NF-κB signaling controls T-helper (Th) 17 differentiation. Proceedings of the National Academy of Sciences of the United States of America. 109: 18529-34. PMID 23091043 DOI: 10.1073/Pnas.1204557109 |
0.405 |
|
| 2012 |
Alegre ML, Molinero LL. The inside story of dendritic cell immunotherapy. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 1363-4. PMID 22642470 DOI: 10.1111/J.1600-6143.2012.04064.X |
0.428 |
|
| 2012 |
Chong AS, Alegre ML. The impact of infection and tissue damage in solid-organ transplantation. Nature Reviews. Immunology. 12: 459-71. PMID 22627862 DOI: 10.1038/Nri3215 |
0.346 |
|
| 2012 |
Porras DL, Wang Y, Zhou P, Molinero LL, Alegre ML. Role of T-cell-specific nuclear factor κB in islet allograft rejection. Transplantation. 93: 976-82. PMID 22437847 DOI: 10.1097/Tp.0B013E31824D11D7 |
0.486 |
|
| 2012 |
Alegre ML, Bromberg JS. Literature watch implications for transplantation. The anti-infectious role of the IL-17 pathway. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 3. PMID 22244121 DOI: 10.1111/J.1600-6143.2011.03937.X |
0.332 |
|
| 2012 |
Alegre ML, Chong AS. "Tip-toeing" to an assay for transplantation tolerance? American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 519-20. PMID 22151375 DOI: 10.1111/J.1600-6143.2011.03871.X |
0.423 |
|
| 2012 |
Molinero LL, Alegre ML. Role of T cell-nuclear factor κB in transplantation. Transplantation Reviews (Orlando, Fla.). 26: 189-200. PMID 22074783 DOI: 10.1016/J.Trre.2011.07.005 |
0.424 |
|
| 2011 |
Ahmed EB, Wang T, Daniels M, Alegre ML, Chong AS. IL-6 induced by Staphylococcus aureus infection prevents the induction of skin allograft acceptance in mice. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 936-46. PMID 21449942 DOI: 10.1111/J.1600-6143.2011.03476.X |
0.386 |
|
| 2011 |
Molinero LL, Miller ML, Evaristo C, Alegre ML. High TCR stimuli prevent induced regulatory T cell differentiation in a NF-κB-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 186: 4609-17. PMID 21411734 DOI: 10.4049/Jimmunol.1002361 |
0.425 |
|
| 2011 |
Ahmed EB, Daniels M, Alegre ML, Chong AS. Bacterial infections, alloimmunity, and transplantation tolerance. Transplantation Reviews (Orlando, Fla.). 25: 27-35. PMID 21126661 DOI: 10.1016/J.Trre.2010.10.003 |
0.421 |
|
| 2010 |
Wang T, Ahmed EB, Chen L, Xu J, Tao J, Wang CR, Alegre ML, Chong AS. Infection with the intracellular bacterium, Listeria monocytogenes, overrides established tolerance in a mouse cardiac allograft model. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 1524-33. PMID 20642679 DOI: 10.1111/J.1600-6143.2010.03066.X |
0.436 |
|
| 2010 |
Bhorade SM, Chen H, Molinero L, Liao C, Garrity ER, Vigneswaran WT, Shilling R, Sperling A, Chong A, Alegre ML. Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome. Transplantation. 90: 540-6. PMID 20628341 DOI: 10.1097/Tp.0B013E3181E8Dabe |
0.64 |
|
| 2009 |
Molinero LL, Yang J, Gajewski T, Abraham C, Farrar MA, Alegre ML. CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 6736-43. PMID 19454668 DOI: 10.4049/Jimmunol.0900498 |
0.323 |
|
| 2009 |
Alegre ML, Chen L, Wang T, Ahmed E, Wang CR, Chong A. Antagonistic effect of toll-like receptor signaling and bacterial infections on transplantation tolerance. Transplantation. 87: S77-9. PMID 19424015 DOI: 10.1097/TP.0b013e3181a2b90f |
0.316 |
|
| 2009 |
Chen L, Ahmed E, Wang T, Wang Y, Ochando J, Chong AS, Alegre ML. TLR Signals promote IL-6/IL-17-dependent transplant rejection Journal of Immunology. 182: 6217-6225. PMID 19414775 DOI: 10.4049/Jimmunol.0803842 |
0.463 |
|
| 2009 |
Molinero LL, Wang Y, Zhou P, Yagita H, Alegre ML. Fas mediates cardiac allograft acceptance in mice with impaired T-cell-intrinsic NF-κB signaling Transplant International. 22: 845-852. PMID 19351347 DOI: 10.1111/J.1432-2277.2009.00875.X |
0.453 |
|
| 2009 |
Zimmer MI, Nguyen HP, Wang B, Xu H, Colmone A, Felio K, Choi HJ, Zhou P, Alegre ML, Wang CR. Polymorphisms in CD1d affect antigen presentation and the activation of CD1d-restricted T cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 1909-14. PMID 19179286 DOI: 10.1073/Pnas.0808476106 |
0.31 |
|
| 2008 |
Ahmed EB, Alegre ML, Chong AS. Role of bacterial infections in allograft rejection. Expert Review of Clinical Immunology. 4: 281-93. PMID 20477057 DOI: 10.1586/1744666X.4.2.281 |
0.335 |
|
| 2008 |
Alegre ML, Leemans J, Le Moine A, Florquin S, De Wilde V, Chong A, Goldman M. The multiple facets of toll-like receptors in transplantation biology. Transplantation. 86: 1-9. PMID 18622268 DOI: 10.1097/Tp.0B013E31817C11E6 |
0.393 |
|
| 2008 |
Wang T, Chen L, Ahmed E, Ma L, Yin D, Zhou P, Shen J, Xu H, Wang CR, Alegre ML, Chong AS. Prevention of allograft tolerance by bacterial infection with Listeria monocytogenes. Journal of Immunology (Baltimore, Md. : 1950). 180: 5991-9. PMID 18424719 |
0.355 |
|
| 2008 |
Chen L, Hussien Y, Hwang KW, Wang Y, Zhou P, Alegre ML. Overexpression of program death-1 in T cells has mild impact on allograft survival. Transplant International : Official Journal of the European Society For Organ Transplantation. 21: 21-9. PMID 18076633 DOI: 10.1111/J.1432-2277.2007.00536.X |
0.376 |
|
| 2007 |
Alegre ML, McNerney ME. Natural killer cell subsets in allograft rejection and tolerance. Current Opinion in Organ Transplantation. 12: 10-16. PMID 27792083 DOI: 10.1097/Mot.0B013E3280129F2A |
0.418 |
|
| 2007 |
Alegre ML, Florquin S, Goldman M. Cellular mechanisms underlying acute graft rejection: time for reassessment Current Opinion in Immunology. 19: 563-568. PMID 17720467 DOI: 10.1016/J.Coi.2007.07.019 |
0.518 |
|
| 2007 |
Vilimas T, Mascarenhas J, Palomero T, Mandal M, Buonamici S, Meng F, Thompson B, Spaulding C, Macaroun S, Alegre ML, Kee BL, Ferrando A, Miele L, Aifantis I. Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. Nature Medicine. 13: 70-7. PMID 17173050 DOI: 10.1038/Nm1524 |
0.358 |
|
| 2006 |
Alegre ML, Najafian N. Costimulatory molecules as targets for the induction of transplantation tolerance. Current Molecular Medicine. 6: 843-57. PMID 17168736 DOI: 10.2174/156652406779010812 |
0.488 |
|
| 2005 |
Zhou P, Balin SJ, Mashayekhi M, Hwang KW, Palucki DA, Alegre ML. Transplantation tolerance in NF-kappaB-impaired mice is not due to regulation but is prevented by transgenic expression of Bcl-xL. Journal of Immunology (Baltimore, Md. : 1950). 174: 3447-53. PMID 15749879 DOI: 10.4049/Jimmunol.174.6.3447 |
0.487 |
|
| 2005 |
Brown IE, Mashayekhi M, Markiewicz M, Alegre ML, Gajewski TF. Peripheral survival of naïve CD8+ T cells. Apoptosis : An International Journal On Programmed Cell Death. 10: 5-11. PMID 15711917 DOI: 10.1007/s10495-005-6056-9 |
0.3 |
|
| 2004 |
Li D, Gál I, Vermes C, Alegre ML, Chong AS, Chen L, Shao Q, Adarichev V, Xu X, Koreny T, Mikecz K, Finnegan A, Glant TT, Zhang J. Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation. Journal of Immunology (Baltimore, Md. : 1950). 173: 7135-9. PMID 15585834 DOI: 10.4049/Jimmunol.173.12.7135 |
0.307 |
|
| 2004 |
Hwang KW, Sweatt WB, Mashayekhi M, Palucki DA, Sattar H, Chuang E, Alegre ML. Transgenic expression of CTLA-4 controls lymphoproliferation in IL-2-deficient mice Journal of Immunology. 173: 5415-5424. PMID 15494488 DOI: 10.4049/Jimmunol.173.9.5415 |
0.422 |
|
| 2004 |
O'Keefe JP, Blaine K, Alegre ML, Gajewski TF. Formation of a central supramolecular activation cluster is not required for activation of naive CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 9351-6. PMID 15192143 DOI: 10.1073/Pnas.0305965101 |
0.456 |
|
| 2004 |
Subudhi SK, Zhou P, Yerian LM, Chin RK, Lo JC, Anders RA, Sun Y, Chen L, Wang Y, Alegre ML, Fu YX. Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection. The Journal of Clinical Investigation. 113: 694-700. PMID 14991067 DOI: 10.1172/Jci19210 |
0.302 |
|
| 2004 |
Rivas FV, O'Keefe JP, Alegre ML, Gajewski TF. Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration. Molecular and Cellular Biology. 24: 1628-39. PMID 14749378 DOI: 10.1128/Mcb.24.4.1628-1639.2004 |
0.362 |
|
| 2004 |
Alegre M. Costimulatory pathways of T-cell activation Kidney International. 65: 1539. DOI: 10.1111/J.1523-1755.2004.05402.X |
0.388 |
|
| 2004 |
Alegre M. Targeting NF-??B in the immune system to prevent acute allograft rejection Current Opinion in Organ Transplantation. 9: 252-257. DOI: 10.1097/01.Mot.0000134870.64589.Aa |
0.318 |
|
| 2003 |
Fallarino F, Grohmann U, Hwang KW, Orabona C, Vacca C, Bianchi R, Belladonna ML, Fioretti MC, Alegre ML, Puccetti P. Modulation of tryptophan catabolism by regulatory T cells. Nature Immunology. 4: 1206-12. PMID 14578884 DOI: 10.1038/Ni1003 |
0.44 |
|
| 2003 |
Zhou P, Hwang KW, Palucki D, Kim O, Newell KA, Fu YX, Alegre ML. Secondary lymphoid organs are important but not absolutely required for allograft responses. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 259-66. PMID 12614279 DOI: 10.1034/J.1600-6143.2003.00067.X |
0.413 |
|
| 2003 |
Zhou P, Hwang KW, Palucki DA, Guo Z, Boothby M, Newell KA, Alegre ML. Impaired NF-kappaB activation in T cells permits tolerance to primary heart allografts and to secondary donor skin grafts. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 139-47. PMID 12603209 DOI: 10.1034/J.1600-6143.2003.00033.X |
0.472 |
|
| 2003 |
Tang Q, Smith JA, Szot GL, Zhou P, Alegre ML, Henriksen KJ, Thompson CB, Bluestone JA. CD28/B7 regulation of anti-CD3-mediated immunosuppression in vivo. Journal of Immunology (Baltimore, Md. : 1950). 170: 1510-6. PMID 12538715 DOI: 10.4049/Jimmunol.170.3.1510 |
0.563 |
|
| 2002 |
Utset TO, Auger JA, Peace D, Zivin RA, Xu D, Jolliffe L, Alegre ML, Bluestone JA, Clark MR. Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial. The Journal of Rheumatology. 29: 1907-13. PMID 12233885 |
0.39 |
|
| 2002 |
Harlin H, Hwang KW, Palucki DA, Kim O, Thompson CB, Boothby M, Alegre ML. CTLA-4 engagement regulates NF-kappaB activation in vivo. European Journal of Immunology. 32: 2095-104. PMID 12209621 DOI: 10.1002/1521-4141(200208)32:8<2095::Aid-Immu2095>3.0.Co;2-E |
0.394 |
|
| 2002 |
Harlin H, Podack E, Boothby M, Alegre ML. TCR-independent CD30 signaling selectively induces IL-13 production via a TNF receptor-associated factor/p38 mitogen-activated protein kinase-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 169: 2451-9. PMID 12193714 DOI: 10.4049/Jimmunol.169.5.2451 |
0.362 |
|
| 2002 |
Hwang KW, Sweatt WB, Brown IE, Blank C, Gajewski TF, Bluestone JA, Alegre ML. Cutting edge: Targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells Journal of Immunology. 169: 633-637. PMID 12097362 DOI: 10.4049/Jimmunol.169.2.633 |
0.53 |
|
| 2001 |
Szot GL, Zhou P, Rulifson I, Wang J, Guo Z, Kim O, Newell KA, Thistlethwaite JR, Bluestone JA, Alegre ML. Different Mechanisms of Cardiac Allograft Rejection in Wildtype and CD28-deficient Mice American Journal of Transplantation. 1: 38-46. PMID 12095035 DOI: 10.1034/J.1600-6143.2001.010108.X |
0.764 |
|
| 2001 |
Alegre ML, Frauwirth KA, Thompson CB. T-cell regulation by CD28 and CTLA-4 Nature Reviews Immunology. 1: 220-228. PMID 11905831 DOI: 10.1038/35105024 |
0.407 |
|
| 2001 |
Frauwirth KA, Alegre ML, Thompson CB. CTLA-4 is not required for induction of CD8+ T cell anergy in vivo Journal of Immunology. 167: 4936-4941. PMID 11673499 DOI: 10.4049/Jimmunol.167.9.4936 |
0.461 |
|
| 2001 |
Guo Z, Wang J, Meng L, Wu Q, Kim O, Hart J, He G, Zhou P, Thistlethwaite JR, Alegre ML, Fu YX, Newell KA. Cutting edge: membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection. Journal of Immunology (Baltimore, Md. : 1950). 167: 4796-800. PMID 11673481 DOI: 10.4049/Jimmunol.167.9.4796 |
0.463 |
|
| 2001 |
Guo Z, Meng L, Kim O, Wang J, Hart J, He G, Alegre ML, Thistlethwaite JR, Pearson TC, Larsen CP, Newell KA. CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway. Transplantation. 71: 1351-4. PMID 11403253 DOI: 10.1097/00007890-200105150-00033 |
0.387 |
|
| 2001 |
Zhou P, Szot G, Guo Z, Kim O, He G, Wang J, Grusby M, Newell K, Thistlethwaite J, Bluestone J, Alegre M. Role of STAT6 signaling in the induction and long-term maintenance of tolerance mediated by CTLA4-Ig. Transplantation Proceedings. 33: 214-6. PMID 11266784 DOI: 10.1016/S0041-1345(00)01979-5 |
0.457 |
|
| 2001 |
Alegre M, Fallarino F, Zhou P, Frauwirth K, Thistlethwaite J, Newell K, Gajewski T, Bluestone J. Transplantation and the CD28/CTLA4/B7 pathway Transplantation Proceedings. 33: 209-211. PMID 11266782 DOI: 10.1016/S0041-1345(00)01977-1 |
0.554 |
|
| 2001 |
Gajewski TF, Fallarino F, Fields PE, Rivas F, Alegre ML. Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: Lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase Journal of Immunology. 166: 3900-3907. PMID 11238634 DOI: 10.4049/Jimmunol.166.6.3900 |
0.441 |
|
| 2000 |
Kouki T, Sawai Y, Gardine CA, Fisfalen ME, Alegre ML, DeGroot LJ. CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. Journal of Immunology (Baltimore, Md. : 1950). 165: 6606-11. PMID 11086105 DOI: 10.4049/Jimmunol.165.11.6606 |
0.352 |
|
| 2000 |
Zhou P, Szot GL, Guo Z, Kim O, He G, Wang J, Grusby MJ, Newell KA, Thistlethwaite JR, Bluestone JA, Alegre ML. Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. Journal of Immunology (Baltimore, Md. : 1950). 165: 5580-7. PMID 11067913 DOI: 10.4049/Jimmunol.165.10.5580 |
0.579 |
|
| 2000 |
Xu D, Alegre ML, Varga SS, Rothermel AL, Collins AM, Pulito VL, Hanna LS, Dolan KP, Parren PW, Bluestone JA, Jolliffe LK, Zivin RA. In vitro characterization of five humanized OKT3 effector function variant antibodies. Cellular Immunology. 200: 16-26. PMID 10716879 DOI: 10.1006/Cimm.2000.1617 |
0.551 |
|
| 2000 |
Frauwirth KA, Alegre ML, Thompson CB. Induction of T cell anergy in the absence of CTLA-4/B7 interaction Journal of Immunology. 164: 2987-2993. PMID 10706686 DOI: 10.4049/Jimmunol.164.6.2987 |
0.425 |
|
| 2000 |
Zhou P, Szot GL, Guo Z, He G, Wang J, Newell KA, Thistlethwaite JR, Bluestone JA, Alegre M. SIGNALING THROUGH STAT4 OR STAT6 IS NOT REQUIRED FOR ACUTE ALLOGRAFT REJECTION OR FOR THE INDUCTION OF TOLERANCE BY CTLA4-IG TREATMENT IN A MURINE CARDIAC TRANSPLANT MODEL. Transplantation. 69: S379. DOI: 10.1097/00007890-200004271-01026 |
0.529 |
|
| 1999 |
Wissing KM, Desalle F, Abramowicz D, Willems F, Leo O, Goldman M, Alegre M. Down-regulation of interleukin-2 and interferon-gamma and maintenance of interleukin-4 and interleukin-10 production after administration of an anti-CD3 monoclonal antibody in mice. Transplantation. 68: 677-684. PMID 10507488 DOI: 10.1097/00007890-199909150-00014 |
0.431 |
|
| 1999 |
Muraille E, Andris F, Pajak B, Wissing KM, Smedt TD, Desalle F, Goldman M, Alegre M, Urbain J, Moser M, Leo O. Downregulation of antigen-presenting cell functions after administration of mitogenic anti-CD3 monoclonal antibodies in mice. Blood. 94: 4347-4357. DOI: 10.1182/Blood.V94.12.4347.424K31_4347_4357 |
0.406 |
|
| 1998 |
Mandal M, Chen XR, Alegre ML, Chiu NM, Chen YH, Castaño AR, Wang CR. Tissue distribution, regulation and intracellular localization of murine CD1 molecules. Molecular Immunology. 35: 525-36. PMID 9809580 DOI: 10.1016/S0161-5890(98)00055-8 |
0.366 |
|
| 1998 |
Noel PJ, Alegre ML, Reiner SL, Thompson CB. Impaired negative selection in CD28-deficient mice Cellular Immunology. 187: 131-138. PMID 9732701 DOI: 10.1006/Cimm.1998.1332 |
0.433 |
|
| 1998 |
Lin H, Rathmell JC, Gray GS, Thompson CB, Leiden JM, Alegre ML. Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. The Journal of Experimental Medicine. 188: 199-204. PMID 9653096 DOI: 10.1084/Jem.188.1.199 |
0.469 |
|
| 1996 |
Cozzi PJ, Padrid P, Tompkins MB, Alegre ML, Takeda J, Leff AR. Bioactivity of recombinant feline interleukin-2 on human and feline leukocytes. Veterinary Immunology and Immunopathology. 48: 27-33. PMID 8533314 DOI: 10.1016/0165-2427(95)05422-3 |
0.305 |
|
| 1995 |
Alegre ML, Lenschow DJ, Bluestone JA. Immunomodulation of transplant rejection using monoclonal antibodies and soluble receptors Digestive Diseases and Sciences. 40: 58-64. PMID 7821120 DOI: 10.1007/Bf02063942 |
0.622 |
|
| 1994 |
Alegre M, Sattar HA, Herold KC, Smith J, Tepper MA, Bluestone JA. PREVENTION OF THE HUMORAL RESPONSE INDUCED BY AN ANTI-CD3 MONOCLONAL ANTIBODY BY DEOXYSPERGUALIN IN A MURINE MODEL1 Transplantation. 57: 1786-1794. DOI: 10.1097/00007890-199406270-00018 |
0.568 |
|
| 1991 |
Alegre M, Gastaldello K, Abramowicz D, Kinnaert P, Vereerstraeten P, Pauw LD, Vandenabeele P, Moser M, Leo O, Goldman M. Evidence that pentoxifylline reduces anti-CD3 monoclonal antibody-induced cytokine release syndrome. Transplantation. 52: 674-679. PMID 1833865 DOI: 10.1097/00007890-199110000-00018 |
0.346 |
|
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