Kevan L. Hartshorn - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Molecular Biology, Cell Biology, General Biology, Oncology

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Alymova IV, Cipollo JF, Parsons LM, Music N, Kamal RP, Tzeng WP, Goldsmith CS, Contessa JN, Hartshorn KL, Wilson JR, Zeng H, Gansebom S, York IA. Aberrant Cellular Glycosylation May Increase the Ability of Influenza Viruses to Escape Host Immune Responses through Modification of the Viral Glycome. Mbio. e0298321. PMID 35285699 DOI: 10.1128/mbio.02983-21  0.341
2021 White MR, Nikolaidis NM, McCormack F, Crouch EC, Hartshorn KL. Viral Evasion of Innate Immune Defense: The Case of Resistance of Pandemic H1N1 Influenza A Virus to Human Mannose-Binding Proteins. Frontiers in Microbiology. 12: 774711. PMID 34956139 DOI: 10.3389/fmicb.2021.774711  0.413
2021 Hsieh IN, White M, Hoeksema M, Deluna X, Hartshorn K. Histone H4 potentiates neutrophil inflammatory responses to influenza A virus: Down-modulation by H4 binding to C-reactive protein and Surfactant protein D. Plos One. 16: e0247605. PMID 33635872 DOI: 10.1371/journal.pone.0247605  0.322
2020 White MR, Hsieh IN, De Luna X, Hartshorn KL. Effects of serum amyloid protein A on influenza A virus replication and viral interactions with neutrophils. Journal of Leukocyte Biology. PMID 33205458 DOI: 10.1002/JLB.4AB0220-116RR  0.323
2020 Hartshorn KL. Innate Immunity and Influenza A Virus Pathogenesis: Lessons for COVID-19. Frontiers in Cellular and Infection Microbiology. 10: 563850. PMID 33194802 DOI: 10.3389/fcimb.2020.563850  0.353
2020 Hsieh IN, Deluna X, White MR, Hartshorn KL. Histone H4 directly stimulates neutrophil activation through membrane permeabilization. Journal of Leukocyte Biology. PMID 32803840 DOI: 10.1002/Jlb.3A0620-342R  0.336
2019 Parsons L, An Y, Qi L, White M, van der Woude R, Hartshorn K, Taubenberger JK, de Vries RP, Cipollo JF. Influenza Hemagglutinins H2, H5, H6, and H11 are not Targets of Pulmonary Surfactant Protein D: N-glycan subtypes in host-pathogen interactions. Journal of Virology. PMID 31826991 DOI: 10.1128/JVI.01951-19  0.365
2019 van Eijk M, Hillaire MLB, Rimmelzwaan GF, Rynkiewicz MJ, White MR, Hartshorn KL, Hessing M, Koolmees PA, Tersteeg MH, van Es MH, Meijerhof T, Huckriede A, Haagsman HP. Enhanced Antiviral Activity of Human Surfactant Protein D by Site-Specific Engineering of the Carbohydrate Recognition Domain. Frontiers in Immunology. 10: 2476. PMID 31749796 DOI: 10.3389/fimmu.2019.02476  0.357
2018 Hsieh IN, De Luna X, White MR, Hartshorn KL. The Role and Molecular Mechanism of Action of Surfactant Protein D in Innate Host Defense Against Influenza A Virus. Frontiers in Immunology. 9: 1368. PMID 29951070 DOI: 10.3389/fimmu.2018.01368  0.394
2018 van Eijk M, Rynkiewicz MJ, Khatri K, Leymarie N, Zaia J, White MR, Hartshorn KL, Cafarella TR, Van Die I, Hessing M, Seaton BA, Haagsman HP. Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. The Journal of Biological Chemistry. PMID 29769321 DOI: 10.1074/Jbc.Ra117.001430  0.37
2018 White MR, Kandel R, Hsieh IN, De Luna X, Hartshorn KL. Critical role of C-terminal residues of the Alzheimer's associated β-amyloid protein in mediating antiviral activity and modulating viral and bacterial interactions with neutrophils. Plos One. 13: e0194001. PMID 29547627 DOI: 10.1371/Journal.Pone.0194001  0.416
2017 Nikolaidis NM, Noel JG, Pitstick LB, Gardner JC, Uehara Y, Wu H, Saito A, Lewnard KE, Liu H, White MR, Hartshorn KL, McCormack FX. Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739896 DOI: 10.1073/Pnas.1621172114  0.398
2017 Luna XD, Hartshorn KL. Influenza Casts a Lung Shadow. American Journal of Pathology. 187: 697-699. PMID 28222276 DOI: 10.1016/J.Ajpath.2017.01.007  0.339
2016 White MR, Tripathi S, Verma A, Kingma P, Takahashi K, Jensenius J, Thiel S, Wang G, Crouch EC, Hartshorn KL. Collectins, H-ficolin and LL-37 reduce influence viral replication in human monocytes and modulate virus-induced cytokine production. Innate Immunity. PMID 27856789 DOI: 10.1177/1753425916678470  0.506
2016 Hsieh IN, Hartshorn KL. The Role of Antimicrobial Peptides in Influenza Virus Infection and Their Potential as Antiviral and Immunomodulatory Therapy. Pharmaceuticals (Basel, Switzerland). 9. PMID 27608030 DOI: 10.3390/Ph9030053  0.404
2016 Khatri K, Klein JA, White MR, Grant OC, Leymarie N, Woods RJ, Hartshorn KL, Zaia J. Integrated omics and computational glycobiology reveal structural basis for Influenza A virus glycan microheterogeneity and host interactions. Molecular & Cellular Proteomics : McP. PMID 26984886 DOI: 10.1074/Mcp.M116.058016  0.39
2016 Hoeksema M, van Eijk M, Haagsman HP, Hartshorn KL. Histones as mediators of host defense, inflammation and thrombosis. Future Microbiology. 11: 441-53. PMID 26939619 DOI: 10.2217/Fmb.15.151  0.304
2015 Tripathi S, Wang G, White M, Rynkiewicz M, Seaton B, Hartshorn K. Identifying the Critical Domain of LL-37 Involved in Mediating Neutrophil Activation in the Presence of Influenza Virus: Functional and Structural Analysis. Plos One. 10: e0133454. PMID 26308522 DOI: 10.1371/Journal.Pone.0133454  0.422
2015 Hoeksema M, Tripathi S, White M, Qi L, Taubenberger J, van Eijk M, Haagsman H, Hartshorn KL. Arginine-rich histones have strong antiviral activity for influenza A viruses. Innate Immunity. PMID 26138524 DOI: 10.1177/1753425915593794  0.339
2015 Tripathi S, Wang G, White M, Qi L, Taubenberger J, Hartshorn KL. Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses. Plos One. 10: e0124706. PMID 25909853 DOI: 10.1371/Journal.Pone.0124706  0.398
2015 Tripathi S, White MR, Hartshorn KL. The amazing innate immune response to influenza A virus infection. Innate Immunity. 21: 73-98. PMID 24217220 DOI: 10.1177/1753425913508992  0.396
2014 Qi L, Pujanauski LM, Davis AS, Schwartzman LM, Chertow DS, Baxter D, Scherler K, Hartshorn KL, Slemons RD, Walters KA, Kash JC, Taubenberger JK. Contemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin. Mbio. 5: e02116. PMID 25406382 DOI: 10.1128/Mbio.02116-14  0.351
2014 Tripathi S, Verma A, Kim EJ, White MR, Hartshorn KL. LL-37 modulates human neutrophil responses to influenza A virus. Journal of Leukocyte Biology. 96: 931-8. PMID 25082153 DOI: 10.1189/Jlb.4A1113-604Rr  0.413
2014 White MR, Kandel R, Tripathi S, Condon D, Qi L, Taubenberger J, Hartshorn KL. Alzheimer's associated β-amyloid protein inhibits influenza A virus and modulates viral interactions with phagocytes. Plos One. 9: e101364. PMID 24988208 DOI: 10.1371/Journal.Pone.0101364  0.442
2014 Nikolaidis NM, White MR, Allen K, Tripathi S, Qi L, McDonald B, Taubenberger J, Seaton BA, McCormack FX, Crouch EC, Hartshorn KL. Mutations flanking the carbohydrate binding site of surfactant protein D confer antiviral activity for pandemic influenza A viruses. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L1036-44. PMID 24705721 DOI: 10.1152/Ajplung.00035.2014  0.483
2014 Nelson B, Zhou X, White M, Hartshorn K, Takahashi K, Kinane TB, Anandaiah A, Koziel H. Recombinant human mannose-binding lectin dampens human alveolar macrophage inflammatory responses to influenza A virus in vitro. Journal of Leukocyte Biology. PMID 24399838 DOI: 10.1189/Jlb.0313161  0.407
2013 Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, Crouch EC, Calin O, Seeberger PH, Schulten K, Seaton BA. Molecular mechanisms of inhibition of influenza by surfactant protein D revealed by large-scale molecular dynamics simulation. Biochemistry. 52: 8527-38. PMID 24224757 DOI: 10.1021/Bi4010683  0.447
2013 Takahashi K, Moyo P, Chigweshe L, Chang WC, White MR, Hartshorn KL. Efficacy of recombinant chimeric lectins, consisting of mannose binding lectin and L-ficolin, against influenza A viral infection in mouse model study. Virus Research. 178: 495-501. PMID 24140629 DOI: 10.1016/J.Virusres.2013.10.001  0.461
2013 Hartshorn KL. Why Does Pandemic Influenza Virus Kill American Journal of Pathology. 183: 1125-1127. PMID 23916382 DOI: 10.1016/J.Ajpath.2013.06.020  0.414
2013 Gally F, Kosmider B, Weaver MR, Pate KM, Hartshorn KL, Oberley-Deegan RE. FABP5 deficiency enhances susceptibility to H1N1 influenza A virus-induced lung inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L64-72. PMID 23624787 DOI: 10.1152/Ajplung.00276.2012  0.418
2013 Tripathi S, Tecle T, Verma A, Crouch E, White M, Hartshorn KL. The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins. The Journal of General Virology. 94: 40-9. PMID 23052388 DOI: 10.1099/Vir.0.045013-0  0.504
2012 Verma A, White M, Vathipadiekal V, Tripathi S, Mbianda J, Ieong M, Qi L, Taubenberger JK, Takahashi K, Jensenius JC, Thiel S, Hartshorn KL. Human H-ficolin inhibits replication of seasonal and pandemic influenza A viruses. Journal of Immunology (Baltimore, Md. : 1950). 189: 2478-87. PMID 22851708 DOI: 10.4049/Jimmunol.1103786  0.438
2012 van Eijk M, Rynkiewicz MJ, White MR, Hartshorn KL, Zou X, Schulten K, Luo D, Crouch EC, Cafarella TR, Head JF, Haagsman HP, Seaton BA. A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D. The Journal of Biological Chemistry. 287: 26666-77. PMID 22685299 DOI: 10.1074/Jbc.M112.368571  0.491
2012 Kosmider B, Messier EM, Janssen WJ, Nahreini P, Wang J, Hartshorn KL, Mason RJ. Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus. Respiratory Research. 13: 43. PMID 22672594 DOI: 10.1186/1465-9921-13-43  0.401
2012 Oiknine-Djian E, Houri-Haddad Y, Weiss EI, Ofek I, Greenbaum E, Hartshorn K, Zakay-Rones Z. High molecular weight constituents of cranberry interfere with influenza virus neuraminidase activity in vitro. Planta Medica. 78: 962-7. PMID 22588835 DOI: 10.1055/S-0031-1298579  0.409
2012 Larvie M, Shoup T, Chang WC, Chigweshe L, Hartshorn K, White MR, Stahl GL, Elmaleh DR, Takahashi K. Mannose-binding lectin binds to amyloid β protein and modulates inflammation. Journal of Biomedicine & Biotechnology. 2012: 929803. PMID 22536027 DOI: 10.1155/2012/929803  0.314
2012 Wang J, Nikrad MP, Travanty EA, Zhou B, Phang T, Gao B, Alford T, Ito Y, Nahreini P, Hartshorn K, Wentworth D, Dinarello CA, Mason RJ. Innate immune response of human alveolar macrophages during influenza A infection. Plos One. 7: e29879. PMID 22396727 DOI: 10.1371/Journal.Pone.0029879  0.452
2012 Doss M, Ruchala P, Tecle T, Gantz D, Verma A, Hartshorn A, Crouch EC, Luong H, Micewicz ED, Lehrer RI, Hartshorn KL. Hapivirins and diprovirins: Novel θ-defensin analogs with potent activity against influenza A virus Journal of Immunology. 188: 2759-2768. PMID 22345650 DOI: 10.4049/Jimmunol.1101335  0.384
2012 Numata M, Kandasamy P, Nagashima Y, Posey J, Hartshorn K, Woodland D, Voelker DR. Phosphatidylglycerol suppresses influenza A virus infection. American Journal of Respiratory Cell and Molecular Biology. 46: 479-87. PMID 22052877 DOI: 10.1165/Rcmb.2011-0194Oc  0.459
2011 Crouch E, Nikolaidis N, McCormack FX, McDonald B, Allen K, Rynkiewicz MJ, Cafarella TM, White M, Lewnard K, Leymarie N, Zaia J, Seaton BA, Hartshorn KL. Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo. The Journal of Biological Chemistry. 286: 40681-92. PMID 21965658 DOI: 10.1074/Jbc.M111.300673  0.493
2011 Sever-Chroneos Z, Murthy A, Davis J, Florence JM, Kurdowska A, Krupa A, Tichelaar JW, White MR, Hartshorn KL, Kobzik L, Whitsett JA, Chroneos ZC. GM-CSF modulates pulmonary resistance to influenza A infection. Antiviral Research. 92: 319-28. PMID 21925209 DOI: 10.1016/J.Antiviral.2011.08.022  0.382
2011 Gong D, Farley K, White M, Hartshorn KL, Benarafa C, Remold-O'Donnell E. Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection. The Journal of Infectious Diseases. 204: 592-600. PMID 21791661 DOI: 10.1093/Infdis/Jir352  0.472
2011 van Eijk M, Bruinsma L, Hartshorn KL, White MR, Rynkiewicz MJ, Seaton BA, Hemrika W, Romijn RA, van Balkom BW, Haagsman HP. Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses. The Journal of Biological Chemistry. 286: 20137-51. PMID 21489996 DOI: 10.1074/Jbc.M111.224469  0.407
2011 Qi L, Kash JC, Dugan VG, Jagger BW, Lau YF, Sheng ZM, Crouch EC, Hartshorn KL, Taubenberger JK. The ability of pandemic influenza virus hemagglutinins to induce lower respiratory pathology is associated with decreased surfactant protein D binding. Virology. 412: 426-34. PMID 21334038 DOI: 10.1016/J.Virol.2011.01.029  0.497
2011 Wang J, Nikrad MP, Phang T, Gao B, Alford T, Ito Y, Edeen K, Travanty EA, Kosmider B, Hartshorn K, Mason RJ. Innate immune response to influenza A virus in differentiated human alveolar type II cells. American Journal of Respiratory Cell and Molecular Biology. 45: 582-91. PMID 21239608 DOI: 10.1165/Rcmb.2010-0108Oc  0.469
2011 Chang WC, Hartshorn KL, White MR, Moyo P, Michelow IC, Koziel H, Kinane BT, Schmidt EV, Fujita T, Takahashi K. Recombinant chimeric lectins consisting of mannose-binding lectin and L-ficolin are potent inhibitors of influenza A virus compared with mannose-binding lectin. Biochemical Pharmacology. 81: 388-95. PMID 21035429 DOI: 10.1016/J.Bcp.2010.10.012  0.433
2011 Takahashi K, Chang W, Moyo P, White MR, Meelu P, Verma A, Stahl GL, Hartshorn KL, Yajnik V. Dietary sugars inhibit biologic functions of the pattern recognition molecule, mannose-binding lectin Open Journal of Immunology. 1: 41-49. DOI: 10.4236/Oji.2011.12005  0.398
2011 Rynkiewicz MJ, Luo D, Leymarie N, Crouch EC, Hartshorn KL, Head JF, McCormack FX, van Eijk M, Zaia J, Seaton BA. Mechanisms of Interaction Between Lung Collectins and Influenza a Virus Hemagglutinin Biophysical Journal. 100: 214a-215a. DOI: 10.1016/J.Bpj.2010.12.1384  0.453
2010 Chang WC, White MR, Moyo P, McClear S, Thiel S, Hartshorn KL, Takahashi K. Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection. Bmc Immunology. 11: 64. PMID 21182784 DOI: 10.1186/1471-2172-11-64  0.426
2010 Hansen S, Selman L, Palaniyar N, Ziegler K, Brandt J, Kliem A, Jonasson M, Skjoedt MO, Nielsen O, Hartshorn K, Jørgensen TJ, Skjødt K, Holmskov U. Collectin 11 (CL-11, CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity. Journal of Immunology (Baltimore, Md. : 1950). 185: 6096-104. PMID 20956340 DOI: 10.4049/Jimmunol.1002185  0.33
2010 Hartshorn KL, White MR, Rynkiewicz M, Sorensen G, Holmskov U, Head J, Crouch EC. Monoclonal antibody-assisted structure-function analysis of the carbohydrate recognition domain of surfactant protein D. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L384-92. PMID 20601494 DOI: 10.1152/Ajplung.00096.2010  0.416
2010 Hartshorn KL, White MR, Smith K, Sorensen G, Kuroki Y, Holmskov U, Head J, Crouch EC. Increasing antiviral activity of surfactant protein d trimers by introducing residues from bovine serum collectins: dissociation of mannan-binding and antiviral activity. Scandinavian Journal of Immunology. 72: 22-30. PMID 20591072 DOI: 10.1111/J.1365-3083.2010.02409.X  0.451
2010 Seaton BA, Crouch EC, McCormack FX, Head JF, Hartshorn KL, Mendelsohn R. Review: Structural determinants of pattern recognition by lung collectins. Innate Immunity. 16: 143-50. PMID 20423923 DOI: 10.1177/1753425910368716  0.375
2010 Tecle T, Tripathi S, Hartshorn KL. Review: Defensins and cathelicidins in lung immunity. Innate Immunity. 16: 151-9. PMID 20418263 DOI: 10.1177/1753425910365734  0.331
2010 White MR, Boland P, Tecle T, Gantz D, Sorenson G, Tornoe I, Holmskov U, McDonald B, Crouch EC, Hartshorn KL. Enhancement of antiviral activity of collectin trimers through cross-linking and mutagenesis of the carbohydrate recognition domain. Journal of Innate Immunity. 2: 267-79. PMID 20375547 DOI: 10.1159/000272313  0.441
2010 Hartshorn KL. Role of surfactant protein A and D (SP-A and SP-D) in human antiviral host defense. Frontiers in Bioscience. 2: 527-546. PMID 20036966 DOI: 10.2741/S83  0.479
2010 Hartshorn KL. New Look at an Old Problem : Bacterial Superinfection after Influenza American Journal of Pathology. 176: 536-539. PMID 20019194 DOI: 10.2353/Ajpath.2010.090880  0.383
2010 Hartshorn KL, White MR, Tecle T, Sørensen GL, Holmskov U, Crouch EC. Viral aggregating and opsonizing activity in collectin trimers. American Journal of Physiology-Lung Cellular and Molecular Physiology. 298. PMID 19837850 DOI: 10.1152/Ajplung.00223.2009  0.48
2010 Doss M, White MR, Tecle T, Hartshorn KL. Human defensins and LL-37 in mucosal immunity Journal of Leukocyte Biology. 87: 79-92. PMID 19808939 DOI: 10.1189/Jlb.0609382  0.348
2009 Doss M, White MR, Tecle T, Gantz D, Crouch EC, Jung G, Ruchala P, Waring AJ, Lehrer RI, Hartshorn KL. Interactions of α-,β-, and θ-defensins with influenza A virus and surfactant protein D Journal of Immunology. 182: 7878-7887. PMID 19494312 DOI: 10.4049/Jimmunol.0804049  0.478
2009 Crouch E, Hartshorn K, Horlacher T, McDonald B, Smith K, Cafarella T, Seaton B, Seeberger PH, Head J. Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343. Biochemistry. 48: 3335-45. PMID 19249874 DOI: 10.1021/Bi8022703  0.416
2009 Wang J, Oberley-Deegan R, Wang S, Nikrad M, Funk CJ, Hartshorn KL, Mason RJ. Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to influenza A infection. Journal of Immunology (Baltimore, Md. : 1950). 182: 1296-304. PMID 19155475 DOI: 10.4049/Jimmunol.182.3.1296  0.334
2009 White MR, Helmerhorst EJ, Ligtenberg A, Karpel M, Tecle T, Siqueira WL, Oppenheim FG, Hartshorn KL. Multiple components contribute to ability of saliva to inhibit influenza viruses Oral Microbiology and Immunology. 24: 18-24. PMID 19121065 DOI: 10.1111/J.1399-302X.2008.00468.X  0.493
2008 White MR, Doss M, Boland P, Tecle T, Hartshorn KL. Innate immunity to influenza virus: implications for future therapy. Expert Review of Clinical Immunology. 4: 497-514. PMID 19756245 DOI: 10.1586/1744666X.4.4.497  0.431
2008 White M, Kingma P, Tecle T, Kacak N, Linders B, Heuser J, Crouch E, Hartshorn K. Multimerization of surfactant protein D, but not its collagen domain, is required for antiviral and opsonic activities related to influenza virus. Journal of Immunology (Baltimore, Md. : 1950). 181: 7936-43. PMID 19017984 DOI: 10.4049/Jimmunol.181.11.7936  0.477
2008 Hartshorn KL, Webby R, White MR, Tecle T, Pan C, Boucher S, Moreland RJ, Crouch EC, Scheule RK. Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D. Respiratory Research. 9: 65. PMID 18811961 DOI: 10.1186/1465-9921-9-65  0.472
2008 Tecle T, White MR, Sørensen GL, Gantz D, Kacak N, Holmskov U, Smith K, Crouch EC, Hartshorn KL. Critical role for cross-linking of trimeric lectin domains of surfactant protein D in antiviral activity against influenza A virus. Biochemical Journal. 412: 323-329. PMID 18302538 DOI: 10.1042/Bj20071663  0.492
2008 Mikerov AN, White M, Hartshorn K, Wang G, Floros J. Inhibition of hemagglutination activity of influenza A viruses by SP-A1 and SP-A2 variants expressed in CHO cells. Medical Microbiology and Immunology. 197: 9-12. PMID 17520282 DOI: 10.1007/S00430-007-0051-4  0.327
2007 White MR, Tecle T, Crouch EC, Hartshorn KL. Impact of neutrophils on antiviral activity of human bronchoalveolar lavage fluid. American Journal of Physiology-Lung Cellular and Molecular Physiology. 293. PMID 17720872 DOI: 10.1152/Ajplung.00266.2007  0.492
2007 Tecle T, White MR, Gantz D, Crouch EC, Hartshorn KL. Human Neutrophil Defensins Increase Neutrophil Uptake of Influenza A Virus and Bacteria and Modify Virus-Induced Respiratory Burst Responses Journal of Immunology. 178: 8046-8052. PMID 17548642 DOI: 10.4049/Jimmunol.178.12.8046  0.504
2007 Tecle T, White MR, Crouch EC, Hartshorn KL. Inhibition of influenza viral neuraminidase activity by collectins. Archives of Virology. 152: 1731-1742. PMID 17514488 DOI: 10.1007/S00705-007-0983-4  0.474
2007 Hartshorn KL, White MR, Tecle T, Tornoe I, Sørensen GL, Crouch EC, Holmskov U. Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D Respiratory Research. 8: 9-9. PMID 17280604 DOI: 10.1186/1465-9921-8-9  0.465
2006 Kingma PS, Zhang L, Ikegami M, Hartshorn K, McCormack FX, Whitsett JA. Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D. The Journal of Biological Chemistry. 281: 24496-505. PMID 16787926 DOI: 10.1074/Jbc.M600651200  0.381
2006 Hartshorn KL, White MR, Tecle T, Holmskov U, Crouch EC. Innate Defense against Influenza A Virus: Activity of Human Neutrophil Defensins and Interactions of Defensins with Surfactant Protein D Journal of Immunology. 176: 6962-6972. PMID 16709857 DOI: 10.4049/Jimmunol.176.11.6962  0.479
2006 Crouch EC, Smith K, McDonald B, Briner D, Linders B, McDonald J, Holmskov U, Head J, Hartshorn K. Species differences in the carbohydrate binding preferences of surfactant protein D. American Journal of Respiratory Cell and Molecular Biology. 35: 84-94. PMID 16514117 DOI: 10.1165/Rcmb.2005-0462Oc  0.389
2006 Lee RM, White MR, Hartshorn KL. Influenza a viruses upregulate neutrophil toll-like receptor 2 expression and function. Scandinavian Journal of Immunology. 63: 81-89. PMID 16476006 DOI: 10.1111/J.1365-3083.2005.01714.X  0.384
2006 Hartshorn KL, Ligtenberg A, White MR, Eijk Mv, Hartshorn M, Pemberton L, Holmskov U, Crouch E. Salivary agglutinin and lung scavenger receptor cysteine-rich glycoprotein 340 have broad anti-influenza activities and interactions with surfactant protein D that vary according to donor source and sialylation. Biochemical Journal. 393: 545-553. PMID 16190864 DOI: 10.1042/Bj20050695  0.415
2005 Meschi J, Crouch EC, Skolnik P, Yahya K, Holmskov U, Leth-Larsen R, Tornoe I, Tecle T, White MR, Hartshorn KL. Surfactant protein D binds to human immunodeficiency virus (HIV) envelope protein gp120 and inhibits HIV replication. The Journal of General Virology. 86: 3097-107. PMID 16227233 DOI: 10.1099/Vir.0.80764-0  0.424
2005 White MM, Crouch E, Vesona J, Tacken PJ, Batenburg JJ, Leth-Larsen R, Holmskov U, Hartshorn KL. Respiratory innate immune proteins differentially modulate the neutrophil respiratory burst response to influenza A virus American Journal of Physiology - Lung Cellular and Molecular Physiology. 289. PMID 15951332 DOI: 10.1152/Ajplung.00130.2005  0.489
2005 Kandel R, Hartshorn KL. Novel strategies for prevention and treatment of influenza. Expert Opinion On Therapeutic Targets. 9: 1-22. PMID 15757479 DOI: 10.1517/14728222.9.1.1  0.39
2005 Crouch E, Tu Y, Briner D, McDonald B, Smith K, Holmskov U, Hartshorn K. Ligand specificity of human surfactant protein D: expression of a mutant trimeric collectin that shows enhanced interactions with influenza A virus. The Journal of Biological Chemistry. 280: 17046-56. PMID 15711012 DOI: 10.1074/Jbc.M413932200  0.457
2005 Leth-Larsen R, Garred P, Jensenius H, Meschi J, Hartshorn K, Madsen J, Tornoe I, Madsen HO, Sørensen G, Crouch E, Holmskov U. A Common Polymorphism in the SFTPD Gene Influences Assembly, Function, and Concentration of Surfactant Protein D Journal of Immunology. 174: 1532-1538. PMID 15661913 DOI: 10.4049/Jimmunol.174.3.1532  0.396
2005 White MR, Crouch E, Eijk Mv, Hartshorn M, Pemberton L, Tornoe I, Holmskov U, Hartshorn KL. Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor American Journal of Physiology-Lung Cellular and Molecular Physiology. 288. PMID 15608147 DOI: 10.1152/Ajplung.00365.2004  0.472
2005 Tecle T, White MR, Hartshorn KL. Innate Immunity to Influenza A Virus Infection Current Respiratory Medicine Reviews. 1: 127-145. DOI: 10.2174/1573398054023073  0.413
2004 Mogues T, Etzerodt M, Hall C, Engelich G, Graversen JH, Hartshorn KL. Tetranectin Binds to the Kringle 1-4 Form of Angiostatin and Modifies Its Functional Activity. Journal of Biomedicine & Biotechnology. 2004: 73-78. PMID 15240916 DOI: 10.1155/S1110724304307096  0.315
2004 Tacken PJ, Hartshorn KL, White MR, van Kooten C, van de Winkel JG, Reid KB, Batenburg JJ. Effective targeting of pathogens to neutrophils via chimeric surfactant protein D/anti-CD89 protein. Journal of Immunology (Baltimore, Md. : 1950). 172: 4934-40. PMID 15067073 DOI: 10.4049/Jimmunol.172.8.4934  0.413
2004 van Eijk M, White MR, Batenburg JJ, Vaandrager AB, van Golde LM, Haagsman HP, Hartshorn KL. Interactions of influenza A virus with sialic acids present on porcine surfactant protein D. American Journal of Respiratory Cell and Molecular Biology. 30: 871-9. PMID 14672916 DOI: 10.1165/Rcmb.2003-0355Oc  0.458
2003 van Eijk M, White MR, Crouch EC, Batenburg JJ, Vaandrager AB, Van Golde LM, Haagsman HP, Hartshorn KL. Porcine pulmonary collectins show distinct interactions with influenza A viruses: role of the N-linked oligosaccharides in the carbohydrate recognition domain. Journal of Immunology (Baltimore, Md. : 1950). 171: 1431-40. PMID 12874235 DOI: 10.4049/Jimmunol.171.3.1431  0.49
2003 Hartshorn KL, White MR, Mogues T, Ligtenberg T, Crouch E, Holmskov U. Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1066-76. PMID 12871854 DOI: 10.1152/Ajplung.00057.2003  0.35
2002 Hartshorn KL, White MR, Crouch EC. Contributions of the N- and C-terminal domains of surfactant protein d to the binding, aggregation, and phagocytic uptake of bacteria. Infection and Immunity. 70: 6129-6139. PMID 12379690 DOI: 10.1128/Iai.70.11.6129-6139.2002  0.426
2002 van Eijk M, van de Lest CH, Batenburg JJ, Vaandrager AB, Meschi J, Hartshorn KL, van Golde LM, Haagsman HP. Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers. American Journal of Respiratory Cell and Molecular Biology. 26: 739-47. PMID 12034574 DOI: 10.1165/Ajrcmb.26.6.4520  0.421
2002 Engelich G, White M, Hartshorn KL. Role of the respiratory burst in co-operative reduction in neutrophil survival by influenza A virus and Escherichia coli. Journal of Medical Microbiology. 51: 484-490. PMID 12018655 DOI: 10.1099/0022-1317-51-6-484  0.342
2002 Hartshorn KL, Holmskov U, Hansen S, Zhang P, Meschi J, Mogues T, White MR, Crouch EC. Distinctive anti-influenza properties of recombinant collectin 43. The Biochemical Journal. 366: 87-96. PMID 11971759 DOI: 10.1042/Bj20011868  0.485
2002 Zhang L, Hartshorn KL, Crouch EC, Ikegami M, Whitsett JA. Complementation of pulmonary abnormalities in SP-D(-/-) mice with an SP-D/conglutinin fusion protein. The Journal of Biological Chemistry. 277: 22453-9. PMID 11956209 DOI: 10.1074/Jbc.M201632200  0.423
2002 LeVine AM, Hartshorn K, Elliott J, Whitsett J, Korfhagen T. Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection American Journal of Physiology - Lung Cellular and Molecular Physiology. 282. PMID 11839553 DOI: 10.1152/Ajplung.00280.2001  0.38
2002 Hartshorn KL, White MR, Ezekowitz RAB, Sastry K, Crouch E. Development of chimeric collectins with enhanced activity against influenza A virus. Advances in Experimental Medicine and Biology. 479: 49-59. PMID 10897409 DOI: 10.1007/0-306-46831-X_5  0.476
2001 Engelich G, Wright DG, Hartshorn KL. Acquired disorders of phagocyte function complicating medical and surgical illnesses. Clinical Infectious Diseases. 33: 2040-2048. PMID 11698988 DOI: 10.1086/324502  0.345
2001 LeVine AM, Whitsett JA, Hartshorn KL, Crouch EC, Korfhagen TR. Surfactant protein D enhances clearance of influenza A virus from the lung in vivo. Journal of Immunology (Baltimore, Md. : 1950). 167: 5868-73. PMID 11698462 DOI: 10.4049/Jimmunol.167.10.5868  0.467
2001 White MR, Crouch E, Chang D, Hartshorn KL. Increased Antiviral and Opsonic Activity of a Highly Multimerized Collectin Chimera Biochemical and Biophysical Research Communications. 286: 206-213. PMID 11485330 DOI: 10.1006/Bbrc.2001.5373  0.476
2001 Kandel R, Hartshorn KL. Prophylaxis and Treatment of Influenza Virus Infection Biodrugs. 15: 303-323. PMID 11437694 DOI: 10.2165/00063030-200115050-00003  0.352
2001 Engelich G, White M, Hartshorn KL. Neutrophil survival is markedly reduced by incubation with influenza virus and Streptococcus pneumoniae: role of respiratory burst. Journal of Leukocyte Biology. 69: 50-56. DOI: 10.1189/Jlb.69.1.50  0.392
2000 White MR, Crouch E, Chang D, Sastry K, Guo N, Engelich G, Takahashi K, Ezekowitz RAB, Hartshorn KL. Enhanced Antiviral and Opsonic Activity of a Human Mannose-Binding Lectin and Surfactant Protein D Chimera Journal of Immunology. 165: 2108-2115. PMID 10925296 DOI: 10.4049/Jimmunol.165.4.2108  0.466
2000 Crouch E, Hartshorn K, Ofek I. Collectins and pulmonary innate immunity. Immunological Reviews. 173: 52-65. PMID 10719667 DOI: 10.1034/J.1600-065X.2000.917311.X  0.439
2000 Hartshorn KL, Sastry KN, Chang D, White MR, Crouch EC. Enhanced anti-influenza activity of a surfactant protein D and serum conglutinin fusion protein American Journal of Physiology - Lung Cellular and Molecular Physiology. 278. PMID 10645895 DOI: 10.1152/Ajplung.2000.278.1.L90  0.452
2000 Hartshorn KL, White MR, Voelker DR, Coburn J, Zaner K, Crouch EC. Mechanism of binding of surfactant protein D to influenza A viruses: importance of binding to haemagglutinin to antiviral activity. Biochemical Journal. 351: 449-458. DOI: 10.1042/Bj3510449  0.461
1999 Hartshorn KL, White MR. Influenza A virus up-regulates neutrophil adhesion molecules and adhesion to biological surfaces. Journal of Leukocyte Biology. 65: 614-622. PMID 10331489 DOI: 10.1002/Jlb.65.5.614  0.353
1999 Colamussi ML, White MR, Crouch E, Hartshorn KL. Influenza A virus accelerates neutrophil apoptosis and markedly potentiates apoptotic effects of bacteria. Blood. 93: 2395-2403. DOI: 10.1182/Blood.V93.7.2395.407A22_2395_2403  0.379
1998 Hartshorn KL, Crouch E, White MR, Colamussi ML, Kakkanatt A, Tauber B, Shepherd V, Sastry KN. Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria American Journal of Physiology - Lung Cellular and Molecular Physiology. 274. PMID 9609735 DOI: 10.1152/Ajplung.1998.274.6.L958  0.398
1997 Hartshorn KL, White MR, Shepherd V, Reid K, Jensenius JC, Crouch EC. Mechanisms of anti-influenza activity of surfactant proteins A and D: comparison with serum collectins. American Journal of Physiology. Lung Cellular and Molecular Physiology. 273: L1156-L1166. PMID 29585337 DOI: 10.1152/Ajplung.1997.273.6.L1156  0.446
1996 Hartshorn K, Chang D, Rust K, White M, Heuser J, Crouch E. Interactions of recombinant human pulmonary surfactant protein D and SP-D multimers with influenza A. The American Journal of Physiology. 271: L753-62. PMID 8944718 DOI: 10.1152/Ajplung.1996.271.5.L753  0.425
1996 Brown-Augsburger P, Hartshorn K, Chang D, Rust K, Fliszar C, Welgus HG, Crouch EC. Site-directed Mutagenesis of Cys-15 and Cys-20 of Pulmonary Surfactant Protein D EXPRESSION OF A TRIMERIC PROTEIN WITH ALTERED ANTI-VIRAL PROPERTIES Journal of Biological Chemistry. 271: 13724-13730. PMID 8662732 DOI: 10.1074/Jbc.271.23.13724  0.43
1996 Hartshorn KL, Reid KBM, White MR, Jensenius JC, Morris SM, Tauber AI, Crouch E. Neutrophil deactivation by influenza A viruses: Mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies Blood. 87: 3450-3461. PMID 8605364 DOI: 10.1182/Blood.V87.8.3450.Bloodjournal8783450  0.5
1994 Liou LS, Sastry R, Hartshorn KL, Lee YM, Okarma TB, Tauber AI, Sastry KN. Bovine conglutinin (BC) mRNA expressed in liver: cloning and characterization of the BC cDNA reveals strong homology to surfactant protein-D Gene. 141: 277-281. PMID 8163202 DOI: 10.1016/0378-1119(94)90585-1  0.318
1994 Hartshorn KL, Crouch EC, White MR, Eggleton P, Tauber AI, Chang D, Sastry K. Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses Journal of Clinical Investigation. 94: 311-319. PMID 8040272 DOI: 10.1172/Jci117323  0.472
1994 Kazhdan M, White MR, Tauber AI, Hartshorn KL. Human neutrophil respiratory burst response to influenza A virus occurs at an intracellular location Journal of Leukocyte Biology. 56: 59-64. PMID 8027671 DOI: 10.1002/Jlb.56.1.59  0.43
1994 Little R, White MR, Hartshorn KL. Interferon-α Enhances Neutrophil Respiratory Burst Responses To Stimulation With Influenza A Virus And Fmlp The Journal of Infectious Diseases. 170: 802-810. PMID 7930721 DOI: 10.1093/Infdis/170.4.802  0.381
1993 Oh SK, Cerda S, Lee BG, Blanchard GC, Walker JE, Hartshorn K. Partial purification and identification of an immunosuppressive factor in AIDS sera. Aids Research and Human Retroviruses. 9: 365-73. PMID 7685613 DOI: 10.1089/Aid.1993.9.365  0.35
1993 Hartshorn KL, Sastry K, White MR, Anders EM, Super M, Ezekowitz RA, Tauber AI. Human mannose-binding protein functions as an opsonin for influenza A viruses. The Journal of Clinical Investigation. 91: 1414-20. PMID 7682571 DOI: 10.1172/Jci116345  0.453
1992 Daigneault DE, Hartshorn KL, Liou LS, Abbruzzi GM, White MR, Oh - SK, Tauber AI. Influenza A virus binding to human neutrophils and cross-linking requirements for activation Blood. 80: 3227-3234. PMID 1334733 DOI: 10.1182/Blood.V80.12.3227.Bloodjournal80123227  0.434
1992 Hartshorn KL, Daigneault DE, White MR, Tauber AI. Anomalous features of human neutrophil activation by influenza A virus are shared by related viruses adn sialic acid-binding lectins Journal of Leukocyte Biology. 51: 230-236. PMID 1311744 DOI: 10.1002/Jlb.51.3.230  0.452
1992 Hartshorn KL, Daigneault DE, White MR, Tuvin M, Tauber JL, Tauber AI. Comparison of influenza A virus and formyl-methionyl-leucyl-phenylalanine activation of the human neutrophil Blood. 79: 1049-1057. PMID 1310628 DOI: 10.1182/Blood.V79.4.1049.1049  0.422
1990 Hartshorn KL, Karnad AB, Tauber AI. Influenza A virus and the neutrophil: A model of natural immunity Journal of Leukocyte Biology. 47: 176-186. PMID 2406357 DOI: 10.1002/Jlb.47.2.176  0.446
1990 Karnad AB, Hartshorn KL, Tauber AI. Effect of nisoldipine on priming and activation of the human neutrophil respiratory burst Agents and Actions. 31: 79-85. PMID 2285025 DOI: 10.1007/Bf02003225  0.31
1990 Hartshorn KL, Collamer M, White MR, Schwartz JH, Tauber AI. Characterization of influenza A virus activation of the human neutrophil. Blood. 75: 218-26. PMID 2153030 DOI: 10.1182/Blood.V75.1.218.218  0.434
1990 Hartshorn KL, Wright J, Collamer MA, White MR, Tauber AI. Human neutrophil stimulation by influenza virus: Relationship of cytoplasmic pH changes to cell activation American Journal of Physiology - Cell Physiology. 258. PMID 2113768 DOI: 10.1152/Ajpcell.1990.258.6.C1070  0.382
1988 Hartshorn KL, Tauber AI. The influenza virus-infected phagocyte. A model of deactivation Hematology/Oncology Clinics of North America. 2: 301-315. PMID 2455702 DOI: 10.1016/S0889-8588(18)30623-3  0.433
1987 Blumberg RS, Paradis T, Hartshorn KL, Vogt M, Ho DD, Hirsch MS, Leban J, Sato VL, Schooley RT. Antibody-dependent cell-mediated cytotoxicity against cells infected with the human immunodeficiency virus. The Journal of Infectious Diseases. 156: 878-84. PMID 3479500 DOI: 10.1093/Infdis/156.6.878  0.315
1987 Hartshorn KL, Vogt MW, Chou TC, Blumberg RS, Byington R, Schooley RT, Hirsch MS. Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon. Antimicrobial Agents and Chemotherapy. 31: 168-72. PMID 3471180 DOI: 10.1128/Aac.31.2.168  0.35
1987 Hartshorn KL, Neumeyer D, Vogt MW, Schooley RT, Hirsch MS. Activity of interferons alpha, beta, and gamma against human immunodeficiency virus replication in vitro. Aids Research and Human Retroviruses. 3: 125-33. PMID 3113463 DOI: 10.1089/Aid.1987.3.125  0.321
1987 Vogt MW, Hartshorn KL, Furman PA, Chou TC, Fyfe JA, Coleman LA, Crumpacker C, Schooley RT, Hirsch MS. Ribavirin antagonizes the effect of azidothymidine on HIV replication. Science (New York, N.Y.). 235: 1376-9. PMID 2435003 DOI: 10.1126/Science.2435003  0.353
1986 Hartshorn KL, Sandstrom EG, Neumeyer D, Paradis TJ, Chou TC, Schooley RT, Hirsch MS. Synergistic inhibition of human T-cell lymphotropic virus type III replication in vitro by phosphonoformate and recombinant alpha-A interferon. Antimicrobial Agents and Chemotherapy. 30: 189-91. PMID 3019235 DOI: 10.1128/Aac.30.1.189  0.317
Show low-probability matches.