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Hazem E. Hassan, Ph.D. - Publications

Affiliations: 
Pharmaceutical Sciences University of Maryland at Baltimore, Baltimore, MD, United States 
Area:
Pharmaceutical Sciences, Clinical Pharmacology
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Thomas S, Hammell DC, Hassan HE, Stinchcomb AL. In Vitro-In Vivo Correlation of Buprenorphine Transdermal Systems Under Normal and Elevated Skin Temperature. Pharmaceutical Research. PMID 37095369 DOI: 10.1007/s11095-023-03487-z  0.592
2022 Shukla S, Bunge AL, Hassan HE, Stinchcomb AL. Investigator Impact on Reproducibility of Drug Bioavailability in Stratum Corneum Sampling by Tape Stripping. Pharmaceutical Research. PMID 35411510 DOI: 10.1007/s11095-022-03199-w  0.62
2021 Shin SH, Yu M, Hammell DC, Ghosh P, Raney SG, Hassan HE, Stinchcomb AL. Evaluation of in vitro/in vivo correlations for three fentanyl transdermal delivery systems using in vitro skin permeation testing and human pharmacokinetic studies under the influence of transient heat application. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34838928 DOI: 10.1016/j.jconrel.2021.11.030  0.742
2020 Shin SH, Rantou E, Raney SG, Ghosh P, Hassan H, Stinchcomb A. Cutaneous Pharmacokinetics of Acyclovir Cream 5% Products: Evaluating Bioequivalence with an In Vitro Permeation Test and an Adaptation of Scaled Average Bioequivalence. Pharmaceutical Research. 37: 210. PMID 33001286 DOI: 10.1007/s11095-020-02821-z  0.711
2020 Viscardi RM, Terrin ML, Magder LS, Davis NL, Dulkerian SJ, Waites KB, Namasivayam A, Kaufman DA, Donohue P, Tuttle DJ, Weitkamp JH, Hassan HE, Eddington ND. Randomised trial of azithromycin to eradicate in preterm infants. Archives of Disease in Childhood. Fetal and Neonatal Edition. PMID 32170033 DOI: 10.1136/Archdischild-2019-318122  0.536
2020 Thomas S, Shin SH, Hammell DC, Hassan HE, Stinchcomb AL. Effect of Controlled Heat Application on Topical Diclofenac Formulations Evaluated by In Vitro Permeation Tests (IVPT) Using Porcine and Human Skin. Pharmaceutical Research. 37: 49. PMID 32034502 DOI: 10.1007/S11095-019-2741-1  0.705
2018 Shin SH, Srivilai J, Ibrahim SA, Strasinger C, Hammell DC, Hassan HE, Stinchcomb AL. The Sensitivity of In Vitro Permeation Tests to Chemical Penetration Enhancer Concentration Changes in Fentanyl Transdermal Delivery Systems. Aaps Pharmscitech. PMID 30084070 DOI: 10.1208/S12249-018-1130-0  0.746
2017 Hedrich WD, Fandy TE, Ashour HM, Wang H, Hassan HE. Antibody-Drug Conjugates: Pharmacokinetic/Pharmacodynamic Modeling, Preclinical Characterization, Clinical Studies, and Lessons Learned. Clinical Pharmacokinetics. PMID 29188435 DOI: 10.1007/S40262-017-0619-0  0.758
2017 Shin SH, Thomas S, Raney SG, Ghosh P, Hammell DC, El-Kamary SS, Chen WH, Billington MM, Hassan HE, Stinchcomb AL. In vitro-in vivo correlations for nicotine transdermal delivery systems evaluated by both in vitro skin permeation (IVPT) and in vivo serum pharmacokinetics under the influence of transient heat application. Journal of Controlled Release : Official Journal of the Controlled Release Society. 270: 76-88. PMID 29175139 DOI: 10.1016/J.Jconrel.2017.11.034  0.727
2017 Yu M, Abdallah IA, Shin SH, Hammell DC, Stinchcomb AL, Hassan HE. LC-MS determination of fentanyl in human serum and application to a fentanyl transdermal delivery pharmacokinetic study. Bioanalysis. PMID 28914084 DOI: 10.4155/Bio-2017-0174  0.703
2017 Shin SH, Ghosh P, Newman B, Hammell DC, Raney SG, Hassan HE, Stinchcomb AL. On the Road to Development of an in Vitro Permeation Test (IVPT) Model to Compare Heat Effects on Transdermal Delivery Systems: Exploratory Studies with Nicotine and Fentanyl. Pharmaceutical Research. PMID 28608140 DOI: 10.1007/S11095-017-2189-0  0.735
2017 Nakhla DS, Hussein LA, Magdy N, Abdallah IA, Hassan HE. Precise simultaneous quantification of methadone and cocaine in rat serum and brain tissue samples following their successive i.p. administration. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1048: 19-29. PMID 28192759 DOI: 10.1016/J.Jchromb.2017.01.048  0.302
2016 Hedrich WD, Hassan HE, Wang H. Insights into CYP2B6-mediated drug-drug interactions. Acta Pharmaceutica Sinica. B. 6: 413-425. PMID 27709010 DOI: 10.1016/J.Apsb.2016.07.016  0.777
2016 Abdallah IA, Hammell DC, Stinchcomb AL, Hassan HE. A fully validated LC-MS/MS method for simultaneous determination of nicotine and its metabolite cotinine in human serum and its application to a pharmacokinetic study after using nicotine transdermal delivery systems with standard heat application in adult smokers. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1020: 67-77. PMID 27023159 DOI: 10.1016/J.Jchromb.2016.03.020  0.599
2016 Abdallah IA, Hammell DC, Hassan HE, Stinchcomb AL. Norelgestromin/ethinyl estradiol intravenous infusion formulation optimization, stability and compatibility testing: A case study to overcome polysorbate 80 interference in chromatographic analysis. Journal of Pharmaceutical and Biomedical Analysis. 125: 145-53. PMID 27018506 DOI: 10.1016/J.Jpba.2016.03.024  0.637
2016 Hedrich WD, Xiao J, Heyward S, Zhang Y, Zhang J, Baer MR, Hassan HE, Wang H. Activation of the constitutive androstane receptor increases the therapeutic index of CHOP in lymphoma treatment. Molecular Cancer Therapeutics. PMID 26823489 DOI: 10.1158/1535-7163.Mct-15-0667  0.762
2015 Fandy TE, Abdallah I, Khayat M, Colby DA, Hassan HE. In vitro characterization of transport and metabolism of the alkaloids: vincamine, vinpocetine and eburnamonine. Cancer Chemotherapy and Pharmacology. PMID 26666648 DOI: 10.1007/S00280-015-2924-3  0.384
2015 Gharavi R, Hedrich W, Wang H, Hassan HE. Transporter-Mediated Disposition of Opioids: Implications for Clinical Drug Interactions. Pharmaceutical Research. 32: 2477-502. PMID 25972096 DOI: 10.1007/S11095-015-1711-5  0.768
2015 Merchan LM, Hassan HE, Terrin ML, Waites KB, Kaufman DA, Ambalavanan N, Donohue P, Dulkerian SJ, Schelonka R, Magder LS, Shukla S, Eddington ND, Viscardi RM. Pharmacokinetics, microbial response, and pulmonary outcomes of multidose intravenous azithromycin in preterm infants at risk for Ureaplasma respiratory colonization. Antimicrobial Agents and Chemotherapy. 59: 570-8. PMID 25385115 DOI: 10.1128/Aac.03951-14  0.588
2015 Hassan HE, Carlson S, Abdallah I, Buttolph T, Glass KC, Fandy TE. Curcumin and dimethoxycurcumin induced epigenetic changes in leukemia cells. Pharmaceutical Research. 32: 863-75. PMID 25186441 DOI: 10.1007/S11095-014-1502-4  0.335
2014 Metcalf MD, Rosicky AD, Hassan HE, Eddington ND, Coop A, Cunningham CW, Mercer SL. Opioids and efflux transporters. Part 4: influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues. Bioorganic & Medicinal Chemistry Letters. 24: 3592-5. PMID 24915880 DOI: 10.1016/J.Bmcl.2014.05.033  0.621
2013 Hassan HE, Myers AL, Lee IJ, Mason CW, Wang D, Sinz MW, Wang H, Eddington ND. Induction of xenobiotic receptors, transporters, and drug metabolizing enzymes by oxycodone. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1060-9. PMID 23439660 DOI: 10.1124/Dmd.112.050401  0.639
2013 Viscardi RM, Othman AA, Hassan HE, Eddington ND, Abebe E, Terrin ML, Kaufman DA, Waites KB. Azithromycin to prevent bronchopulmonary dysplasia in ureaplasma-infected preterm infants: pharmacokinetics, safety, microbial response, and clinical outcomes with a 20-milligram-per-kilogram single intravenous dose. Antimicrobial Agents and Chemotherapy. 57: 2127-33. PMID 23439637 DOI: 10.1128/Aac.02183-12  0.585
2012 Molnari JC, Hassan HE, Myers AL. Effects of sertraline on the pharmacokinetics of bupropion and its major metabolite, hydroxybupropion, in mice. European Journal of Drug Metabolism and Pharmacokinetics. 37: 57-63. PMID 21928040 DOI: 10.1007/S13318-011-0065-6  0.429
2011 Molnari JC, Hassan HE, Moeller BM, Myers AL. Drug interaction study between bupropion and ticlopidine in male CF-1 mice. Biological & Pharmaceutical Bulletin. 34: 447-51. PMID 21372402 DOI: 10.1248/Bpb.34.447  0.415
2011 Hassan HE, Othman AA, Eddington ND, Duffy L, Xiao L, Waites KB, Kaufman DA, Fairchild KD, Terrin ML, Viscardi RM. Pharmacokinetics, safety, and biologic effects of azithromycin in extremely preterm infants at risk for ureaplasma colonization and bronchopulmonary dysplasia. Journal of Clinical Pharmacology. 51: 1264-75. PMID 21098694 DOI: 10.1177/0091270010382021  0.579
2010 Li L, Hassan HE, Tolson AH, Ferguson SS, Eddington ND, Wang H. Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells. The Journal of Pharmacology and Experimental Therapeutics. 335: 562-71. PMID 20829393 DOI: 10.1124/Jpet.110.173187  0.635
2010 Myers AL, Hassan HE, Lee IJ, Eddington ND. Repeated administration of oxycodone modifies the gene expression of several drug metabolising enzymes in the hepatic tissue of male Sprague-Dawley rats, including glutathione S-transferase A-5 (rGSTA5) and CYP3A2. The Journal of Pharmacy and Pharmacology. 62: 189-96. PMID 20487198 DOI: 10.1211/Jpp.62.02.0006  0.627
2010 Mason CW, Hassan HE, Kim KP, Cao J, Eddington ND, Newman AH, Voulalas PJ. Characterization of the transport, metabolism, and pharmacokinetics of the dopamine D3 receptor-selective fluorenyl- and 2-pyridylphenyl amides developed for treatment of psychostimulant abuse. The Journal of Pharmacology and Experimental Therapeutics. 333: 854-64. PMID 20228156 DOI: 10.1124/Jpet.109.165084  0.65
2010 Hassan HE, Myers AL, Lee IJ, Chen H, Coop A, Eddington ND. Regulation of gene expression in brain tissues of rats repeatedly treated by the highly abused opioid agonist, oxycodone: microarray profiling and gene mapping analysis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 157-67. PMID 19786507 DOI: 10.1124/Dmd.109.029199  0.646
2009 Hassan HE, Mercer SL, Cunningham CW, Coop A, Eddington ND. Evaluation of the P-glycoprotein (Abcb1) affinity status of a series of morphine analogs: comparative study with meperidine analogs to identify opioids with minimal P-glycoprotein interactions. International Journal of Pharmaceutics. 375: 48-54. PMID 19481690 DOI: 10.1016/J.Ijpharm.2009.03.037  0.636
2009 Teksin ZS, Lee IJ, Nemieboka NN, Othman AA, Upreti VV, Hassan HE, Syed SS, Prisinzano TE, Eddington ND. Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 72: 471-7. PMID 19462483 DOI: 10.1016/J.Ejpb.2009.01.002  0.762
2009 Hassan HE, Myers AL, Coop A, Eddington ND. Differential involvement of P-glycoprotein (ABCB1) in permeability, tissue distribution, and antinociceptive activity of methadone, buprenorphine, and diprenorphine: in vitro and in vivo evaluation. Journal of Pharmaceutical Sciences. 98: 4928-40. PMID 19370547 DOI: 10.1002/Jps.21770  0.643
2009 Coles LD, Lee IJ, Hassan HE, Eddington ND. Distribution of saquinavir, methadone, and buprenorphine in maternal brain, placenta, and fetus during two different gestational stages of pregnancy in mice. Journal of Pharmaceutical Sciences. 98: 2832-46. PMID 19116954 DOI: 10.1002/Jps.21644  0.738
2008 Cunningham CW, Mercer SL, Hassan HE, Traynor JR, Eddington ND, Coop A. Opioids and efflux transporters. Part 2: P-glycoprotein substrate activity of 3- and 6-substituted morphine analogs. Journal of Medicinal Chemistry. 51: 2316-20. PMID 18311899 DOI: 10.1021/Jm701457J  0.617
2007 Hassan HE, Myers AL, Lee IJ, Coop A, Eddington ND. Oxycodone induces overexpression of P-glycoprotein (ABCB1) and affects paclitaxel's tissue distribution in Sprague Dawley rats. Journal of Pharmaceutical Sciences. 96: 2494-506. PMID 17593551 DOI: 10.1002/Jps.20893  0.605
2007 Mercer SL, Hassan HE, Cunningham CW, Eddington ND, Coop A. Opioids and efflux transporters. Part 1: P-glycoprotein substrate activity of N-substituted analogs of meperidine. Bioorganic & Medicinal Chemistry Letters. 17: 1160-2. PMID 17251015 DOI: 10.1016/J.Bmcl.2006.12.042  0.622
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