Eric Schirmer, PhD - Publications

Affiliations: 
University of Edinburgh, Edinburgh, Scotland, United Kingdom 

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Czapiewski R, Schirmer EC. Enhancers on the edge - how the nuclear envelope controls gene regulatory elements. Current Opinion in Genetics & Development. 87: 102234. PMID 39047586 DOI: 10.1016/j.gde.2024.102234  0.795
2023 Rizzotto A, Tollis S, Pham NT, Zheng Y, Abad MA, Wildenhain J, Jeyaprakash AA, Auer M, Tyers M, Schirmer EC. Reduction in Nuclear Size by DHRS7 in Prostate Cancer Cells and by Estradiol Propionate in DHRS7-Depleted Cells. Cells. 13. PMID 38201261 DOI: 10.3390/cells13010057  0.763
2022 de Las Heras JI, Todorow V, Krečinić-Balić L, Hintze S, Czapiewski R, Webb S, Schoser B, Meinke P, Schirmer EC. Metabolic, fibrotic, and splicing pathways are all altered in Emery-Dreifuss muscular dystrophy Spectrum patients to differing degrees. Human Molecular Genetics. PMID 36282542 DOI: 10.1093/hmg/ddac264  0.781
2022 Tollis S, Rizzotto A, Pham NT, Koivukoski S, Sivakumar A, Shave S, Wildenhain J, Zuleger N, Keys JT, Culley J, Zheng Y, Lammerding J, Carragher NO, Brunton VG, Latonen L, ... ... Schirmer EC, et al. Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion. Acs Chemical Biology. 17: 680-700. PMID 35199530 DOI: 10.1021/acschembio.2c00004  0.779
2022 Czapiewski R, Batrakou DG, de Las Heras JI, Carter RN, Sivakumar A, Sliwinska M, Dixon CR, Webb S, Lattanzi G, Morton NM, Schirmer EC. Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy. Nature Communications. 13: 321. PMID 35027552 DOI: 10.1038/s41467-021-27869-2  0.791
2021 Dixon CR, Malik P, de Las Heras JI, Saiz-Ros N, de Lima Alves F, Tingey M, Gaunt E, Richardson AC, Kelly DA, Goldberg MW, Towers GJ, Yang W, Rappsilber J, Digard P, Schirmer EC. STING nuclear partners contribute to innate immune signaling responses. Iscience. 24: 103055. PMID 34541469 DOI: 10.1016/j.isci.2021.103055  0.809
2020 Gatticchi L, de Las Heras JI, Sivakumar A, Zuleger N, Roberti R, Schirmer EC. Disruption Alters Radial Gene Positioning in Mouse Liver Leading to Metabolic Defects and Diabetes Characteristics. Frontiers in Cell and Developmental Biology. 8: 592573. PMID 33330474 DOI: 10.3389/fcell.2020.592573  0.828
2020 Tsatskis Y, Rosenfeld R, Pearson JD, Boswell C, Qu Y, Kim K, Fabian L, Mohammad A, Wang X, Robson MI, Krchma K, Wu J, Gonçalves J, Hodzic D, Wu S, ... ... Schirmer EC, et al. The NEMP family supports metazoan fertility and nuclear envelope stiffness. Science Advances. 6: eabb4591. PMID 32923640 DOI: 10.1126/Sciadv.Abb4591  0.637
2020 Mudumbi KC, Czapiewski R, Ruba A, Junod SL, Li Y, Luo W, Ngo C, Ospina V, Schirmer EC, Yang W. Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores. Nature Communications. 11: 2184. PMID 32366843 DOI: 10.1038/S41467-020-16033-X  0.765
2020 Tsatskis Y, Rosenfeld R, Pearson JD, Boswell C, Qu Y, Kim K, Fabian L, Mohammad A, Wang X, Robson MI, Krchma K, Wu J, Gonçalves J, Hodzic D, Wu S, ... ... Schirmer EC, et al. The NEMP family supports metazoan fertility and nuclear envelope stiffness Science Advances. 6: eabb4591. DOI: 10.1126/sciadv.abb4591  0.664
2019 Meinke P, Kerr ARW, Czapiewski R, de Las Heras JI, Dixon CR, Harris E, Kölbel H, Muntoni F, Schara U, Straub V, Schoser B, Wehnert M, Schirmer EC. A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism. Ebiomedicine. PMID 31862442 DOI: 10.1016/J.Ebiom.2019.11.048  0.805
2019 Tingey M, Mudumbi KC, Schirmer EC, Yang W. Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins. International Journal of Molecular Sciences. 20. PMID 31652739 DOI: 10.3390/Ijms20215248  0.399
2019 Makarov AA, Zou J, Houston DR, Spanos C, Solovyova AS, Cardenal-Peralta C, Rappsilber J, Schirmer EC. Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity. Nature Communications. 10: 3056. PMID 31296869 DOI: 10.1038/S41467-019-11063-6  0.792
2019 Duan J, Navarro-Dorado J, Clark JH, Kinnear NP, Meinke P, Schirmer EC, Evans AM. The cell-wide web coordinates cellular processes by directing site-specific Ca flux across cytoplasmic nanocourses. Nature Communications. 10: 2299. PMID 31127110 DOI: 10.1038/S41467-019-10055-W  0.524
2019 Sivakumar A, de Las Heras JI, Schirmer EC. Spatial Genome Organization: From Development to Disease. Frontiers in Cell and Developmental Biology. 7: 18. PMID 30949476 DOI: 10.3389/Fcell.2019.00018  0.623
2019 Saiz-Ros N, Czapiewski R, Epifano I, Stevenson A, Swanson SK, Dixon CR, Zamora DB, McElwee M, Vijayakrishnan S, Richardson CA, Dong L, Kelly DA, Pytowski L, Goldberg MW, Florens L, ... ... Schirmer EC, et al. Host Vesicle Fusion Protein VAPB Contributes to the Nuclear Egress Stage of Herpes Simplex Virus Type-1 (HSV-1) Replication. Cells. 8. PMID 30717447 DOI: 10.3390/Cells8020120  0.816
2018 Bikkul MU, Faragher RGA, Worthington G, Meinke P, Kerr ARW, Sammy A, Riyahi K, Horton D, Schirmer EC, Hubank M, Kill IR, Anderson RM, Slijepcevic P, Makarov E, Bridger JM. Telomere elongation through hTERT immortalisation leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford Progeria syndrome fibroblasts, expressing a novel SUN1 isoform. Genes, Chromosomes & Cancer. PMID 30474255 DOI: 10.1002/Gcc.22711  0.597
2018 Capitanchik C, Dixon C, Swanson SK, Florens L, Kerr ARW, Schirmer EC. Analysis of RNA-Seq datasets reveals enrichment of tissue-specific splice variants for nuclear envelope proteins. Nucleus (Austin, Tex.). PMID 29912636 DOI: 10.1080/19491034.2018.1469351  0.829
2017 Rizzotto A, Schirmer EC. Breaking the scale: how disrupting the karyoplasmic ratio gives cancer cells an advantage for metastatic invasion. Biochemical Society Transactions. 45: 1333-1344. PMID 29150524 DOI: 10.1042/Bst20170153  0.776
2017 Zhiteneva A, Bonfiglio JJ, Makarov A, Colby T, Vagnarelli P, Schirmer EC, Matic I, Earnshaw WC. Mitotic post-translational modifications of histones promote chromatin compaction in vitro. Open Biology. 7. PMID 28903997 DOI: 10.1098/Rsob.170076  0.8
2017 Robson MI, de Las Heras JI, Czapiewski R, Sivakumar A, Kerr ARW, Schirmer E. Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments. Genome Research. PMID 28424353 DOI: 10.1101/Gr.212308.116  0.802
2017 Dixon CR, Platani M, Makarov AA, Schirmer EC. Microinjection of Antibodies Targeting the Lamin A/C Histone-Binding Site Blocks Mitotic Entry and Reveals Separate Chromatin Interactions with HP1, CenpB and PML. Cells. 6. PMID 28346356 DOI: 10.3390/cells6020009  0.799
2017 de Castro IJ, Budzak J, Di Giacinto ML, Ligammari L, Gokhan E, Spanos C, Moralli D, Richardson C, de Las Heras JI, Salatino S, Schirmer EC, Ullman KS, Bickmore WA, Green C, Rappsilber J, et al. Repo-Man/PP1 regulates heterochromatin formation in interphase. Nature Communications. 8: 14048. PMID 28091603 DOI: 10.1038/Ncomms14048  0.343
2017 de Las Heras JI, Zuleger N, Batrakou DG, Czapiewski R, Kerr AR, Schirmer EC. Tissue-specific NETs alter genome organization and regulation even in a heterologous system. Nucleus (Austin, Tex.). 1-17. PMID 28045568 DOI: 10.1080/19491034.2016.1261230  0.804
2016 Le Thanh P, Meinke P, Korfali N, Srsen V, Robson MI, Wehnert M, Schoser B, Sewry CA, Schirmer EC. Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology. Neuromuscular Disorders : Nmd. PMID 28214269 DOI: 10.1016/J.Nmd.2016.12.003  0.835
2016 Meinke P, Schirmer EC. The increasing relevance of nuclear envelope myopathies. Current Opinion in Neurology. 29: 651-61. PMID 27389815 DOI: 10.1097/Wco.0000000000000359  0.58
2016 Robson MI, de Las Heras JI, Czapiewski R, Lê Thành P, Booth DG, Kelly DA, Webb S, Kerr AR, Schirmer EC. Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis. Molecular Cell. PMID 27264872 DOI: 10.1016/J.Molcel.2016.04.035  0.815
2016 Czapiewski R, Robson MI, Schirmer EC. Anchoring a Leviathan: How the Nuclear Membrane Tethers the Genome. Frontiers in Genetics. 7: 82. PMID 27200088 DOI: 10.3389/Fgene.2016.00082  0.848
2016 Robson MI, Schirmer EC. The Application of DamID to Identify Peripheral Gene Sequences in Differentiated and Primary Cells. Methods in Molecular Biology (Clifton, N.J.). 1411: 359-86. PMID 27147054 DOI: 10.1007/978-1-4939-3530-7_23  0.671
2016 Korfali N, Florens L, Schirmer EC. Isolation, Proteomic Analysis, and Microscopy Confirmation of the Liver Nuclear Envelope Proteome. Methods in Molecular Biology (Clifton, N.J.). 1411: 3-44. PMID 27147032 DOI: 10.1007/978-1-4939-3530-7_1  0.821
2016 Makarov AA, Rizzotto A, Meinke P, Schirmer EC. Purification of Lamins and Soluble Fragments of NETs. Methods in Enzymology. 569: 79-100. PMID 26778554 DOI: 10.1016/Bs.Mie.2015.09.006  0.829
2015 Worman HJ, Schirmer EC. Nuclear membrane diversity: underlying tissue-specific pathologies in disease? Current Opinion in Cell Biology. 34: 101-12. PMID 26115475 DOI: 10.1016/J.Ceb.2015.06.003  0.361
2015 Meinke P, Schirmer EC. LINC'ing form and function at the nuclear envelope. Febs Letters. 589: 2514-21. PMID 26096784 DOI: 10.1016/J.Febslet.2015.06.011  0.604
2015 Batrakou DG, de Las Heras JI, Czapiewski R, Mouras R, Schirmer EC. TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation. Plos One. 10: e0127712. PMID 26024229 DOI: 10.1371/Journal.Pone.0127712  0.829
2015 Agirre X, Castellano G, Pascual M, Heath S, Kulis M, Segura V, Bergmann A, Esteve A, Merkel A, Raineri E, Agueda L, Blanc J, Richardson D, Clarke L, Datta A, ... ... Schirmer EC, et al. Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers. Genome Research. 25: 478-87. PMID 25644835 DOI: 10.1016/J.Clml.2015.07.243  0.587
2015 Meinke P, Schneiderat P, Srsen V, Korfali N, Lê Thành P, Cowan GJ, Cavanagh DR, Wehnert M, Schirmer EC, Walter MC. Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy. Neuromuscular Disorders : Nmd. 25: 127-36. PMID 25454731 DOI: 10.1016/J.Nmd.2014.09.012  0.79
2015 Zhdanov R, Schirmer E, Venkatasubramani AV, Kerr A, Mandrou E, Blanco GR, Kagansky A. Lipids contribute to epigenetic control via chromatin structure and functions Scienceopen Research. DOI: 10.14293/S2199-1006.1.Sor-Life.Auxytr.V2  0.371
2015 Zhdanov R, Schirmer E, Venkatasubramani AV, Kerr A, Mandrou E, Blanco GR, Kagansky A. Lipids contribute to epigenetic control via chromatin structure and functions: Epigenetics is Getting Fat: How lipids may be involved in the structure of the genome and it's regulation Scienceopen Research. DOI: 10.14293/S2199-1006.1.Sor-Life.Auxytr.V1  0.301
2015 Agirre X, Castellano G, Pascual M, Heath S, Kulis M, Segura V, Bergmann A, Esteve A, Merkel A, Raineri E, Agueda L, Blanc J, Richardson D, Clarke L, Datta A, ... ... Schirmer E, et al. Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers Clinical Lymphoma Myeloma and Leukemia. 15: e86-e87. DOI: 10.1016/J.CLML.2015.07.243  0.552
2014 Malik P, Zuleger N, de las Heras JI, Saiz-Ros N, Makarov AA, Lazou V, Meinke P, Waterfall M, Kelly DA, Schirmer EC. NET23/STING promotes chromatin compaction from the nuclear envelope. Plos One. 9: e111851. PMID 25386906 DOI: 10.1371/Journal.Pone.0111851  0.804
2014 Stancheva I, Schirmer EC. Nuclear envelope: connecting structural genome organization to regulation of gene expression. Advances in Experimental Medicine and Biology. 773: 209-44. PMID 24563350 DOI: 10.1007/978-1-4899-8032-8_10  0.447
2014 Robson MI, Le Thanh P, Schirmer EC. NETs and cell cycle regulation. Advances in Experimental Medicine and Biology. 773: 165-85. PMID 24563348 DOI: 10.1007/978-1-4899-8032-8_8  0.662
2014 Agirre X, Castellano G, Pascual M, Kulis M, Segura V, Bergmann A, Esteve A, Merkel A, Raineri E, Agueda L, Blanc J, Richardson D, Clarke L, Russiñol N, Queirós AC, ... ... Schirmer EC, et al. Whole-genome epigenomic analysis in multiple myeloma reveals DNA hypermethylation of b-cell specific enhancers Blood. 124: 2032-2032. DOI: 10.1182/Blood.V124.21.2032.2032  0.59
2013 de Las Heras JI, Meinke P, Batrakou DG, Srsen V, Zuleger N, Kerr AR, Schirmer EC. Tissue specificity in the nuclear envelope supports its functional complexity. Nucleus (Austin, Tex.). 4: 460-77. PMID 24213376 DOI: 10.4161/Nucl.26872  0.833
2013 Zuleger N, Kelly DA, Schirmer EC. Considering discrete protein pools when measuring the dynamics of nuclear membrane proteins. Methods in Molecular Biology (Clifton, N.J.). 1042: 275-98. PMID 23980015 DOI: 10.1007/978-1-62703-526-2_20  0.805
2013 Zuleger N, Boyle S, Kelly DA, de las Heras JI, Lazou V, Korfali N, Batrakou DG, Randles KN, Morris GE, Harrison DJ, Bickmore WA, Schirmer EC. Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery. Genome Biology. 14: R14. PMID 23414781 DOI: 10.1186/Gb-2013-14-2-R14  0.817
2013 de Las Heras JI, Batrakou DG, Schirmer EC. Cancer biology and the nuclear envelope: a convoluted relationship. Seminars in Cancer Biology. 23: 125-37. PMID 22311402 DOI: 10.1016/j.semcancer.2012.01.008  0.819
2013 Korfali N, Srsen V, Waterfall M, Batrakou DG, Pekovic V, Hutchison CJ, Schirmer EC. Percentage of cells in each cell cycle phase by flow cytometry for knockdown of NET4/TMEM53 and controls in U2OS cells. Plos One. DOI: 10.1371/Journal.Pone.0018762.T002  0.767
2012 Korfali N, Wilkie GS, Swanson SK, Srsen V, de Las Heras J, Batrakou DG, Malik P, Zuleger N, Kerr AR, Florens L, Schirmer EC. The nuclear envelope proteome differs notably between tissues. Nucleus (Austin, Tex.). 3: 552-64. PMID 22990521 DOI: 10.4161/Nucl.22257  0.806
2012 Malik P, Tabarraei A, Kehlenbach RH, Korfali N, Iwasawa R, Graham SV, Schirmer EC. Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways. The Journal of Biological Chemistry. 287: 12277-92. PMID 22334672 DOI: 10.1074/Jbc.M111.331777  0.813
2012 Zuleger N, Kerr AR, Schirmer EC. Many mechanisms, one entrance: membrane protein translocation into the nucleus. Cellular and Molecular Life Sciences : Cmls. 69: 2205-16. PMID 22327555 DOI: 10.1007/S00018-012-0929-1  0.81
2011 Srsen V, Korfali N, Schirmer EC. Nuclear envelope influences on cell-cycle progression. Biochemical Society Transactions. 39: 1742-6. PMID 22103518 DOI: 10.1042/Bst20110656  0.843
2011 Kerr AR, Schirmer EC. FG repeats facilitate integral protein trafficking to the inner nuclear membrane. Communicative & Integrative Biology. 4: 557-9. PMID 22046461 DOI: 10.4161/cib.4.5.16052  0.354
2011 Zuleger N, Robson MI, Schirmer EC. The nuclear envelope as a chromatin organizer. Nucleus (Austin, Tex.). 2: 339-49. PMID 21970986 DOI: 10.4161/Nucl.2.5.17846  0.827
2011 Korfali N, Srsen V, Waterfall M, Batrakou DG, Pekovic V, Hutchison CJ, Schirmer EC. A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal. Plos One. 6: e18762. PMID 21533191 DOI: 10.1371/Journal.Pone.0018762  0.818
2011 Zuleger N, Kelly DA, Richardson AC, Kerr AR, Goldberg MW, Goryachev AB, Schirmer EC. System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics. The Journal of Cell Biology. 193: 109-23. PMID 21444689 DOI: 10.1083/Jcb.201009068  0.811
2011 Wilkie GS, Korfali N, Swanson SK, Malik P, Srsen V, Batrakou DG, de las Heras J, Zuleger N, Kerr AR, Florens L, Schirmer EC. Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations. Molecular & Cellular Proteomics : McP. 10: M110.003129. PMID 20876400 DOI: 10.1074/Mcp.M110.003129  0.809
2010 Korfali N, Wilkie GS, Swanson SK, Srsen V, Batrakou DG, Fairley EA, Malik P, Zuleger N, Goncharevich A, de Las Heras J, Kelly DA, Kerr AR, Florens L, Schirmer EC. The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture. Molecular & Cellular Proteomics : McP. 9: 2571-85. PMID 20693407 DOI: 10.1074/Mcp.M110.002915  0.817
2010 Malik P, Korfali N, Srsen V, Lazou V, Batrakou DG, Zuleger N, Kavanagh DM, Wilkie GS, Goldberg MW, Schirmer EC. Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope. Cellular and Molecular Life Sciences : Cmls. 67: 1353-69. PMID 20091084 DOI: 10.1007/S00018-010-0257-2  0.814
2010 Malik P, Zuleger N, Schirmer EC. Nuclear envelope influences on genome organization. Biochemical Society Transactions. 38: 268-72. PMID 20074072 DOI: 10.1042/Bst0380268  0.83
2009 Ostlund C, Guan T, Figlewicz DA, Hays AP, Worman HJ, Gerace L, Schirmer EC. Reduction of a 4q35-encoded nuclear envelope protein in muscle differentiation. Biochemical and Biophysical Research Communications. 389: 279-83. PMID 19716805 DOI: 10.1016/J.Bbrc.2009.08.133  0.599
2009 Korfali N, Fairley EA, Swanson SK, Florens L, Schirmer EC. Use of sequential chemical extractions to purify nuclear membrane proteins for proteomics identification. Methods in Molecular Biology (Clifton, N.J.). 528: 201-25. PMID 19153695 DOI: 10.1007/978-1-60327-310-7_15  0.812
2009 Batrakou DG, Kerr AR, Schirmer EC. Comparative proteomic analyses of the nuclear envelope and pore complex suggests a wide range of heretofore unexpected functions. Journal of Proteomics. 72: 56-70. PMID 18852071 DOI: 10.1016/j.jprot.2008.09.004  0.815
2008 Zuleger N, Korfali N, Schirmer EC. Inner nuclear membrane protein transport is mediated by multiple mechanisms. Biochemical Society Transactions. 36: 1373-7. PMID 19021558 DOI: 10.1042/Bst0361373  0.823
2008 Wilkie GS, Schirmer EC. Purification of nuclei and preparation of nuclear envelopes from skeletal muscle. Methods in Molecular Biology (Clifton, N.J.). 463: 23-41. PMID 18951158 DOI: 10.1007/978-1-59745-406-3_2  0.72
2008 Schirmer EC. The epigenetics of nuclear envelope organization and disease. Mutation Research. 647: 112-21. PMID 18722388 DOI: 10.1016/j.mrfmmm.2008.07.012  0.384
2008 Florens L, Korfali N, Schirmer EC. Subcellular fractionation and proteomics of nuclear envelopes. Methods in Molecular Biology (Clifton, N.J.). 432: 117-37. PMID 18370014 DOI: 10.1007/978-1-59745-028-7_8  0.802
2007 Kavanagh DM, Powell WE, Malik P, Lazou V, Schirmer EC. Organelle proteome variation among different cell types: lessons from nuclear membrane proteins. Sub-Cellular Biochemistry. 43: 51-76. PMID 17953391 DOI: 10.1007/978-1-4020-5943-8_5  0.79
2007 Schirmer EC, Foisner R. Proteins that associate with lamins: many faces, many functions. Experimental Cell Research. 313: 2167-79. PMID 17451680 DOI: 10.1016/j.yexcr.2007.03.012  0.649
2006 Malik P, Schirmer E. The Kaposi's sarcoma-associated herpesvirus ORF57 protein: a pleurotropic regulator of gene expression. Biochemical Society Transactions. 34: 705-710. PMID 17052179 DOI: 10.1042/Bst0340705  0.73
2006 Wilkie GS, Schirmer EC. Guilt by association: the nuclear envelope proteome and disease. Molecular & Cellular Proteomics : McP. 5: 1865-75. PMID 16790741 DOI: 10.1074/mcp.R600003-MCP200  0.713
2005 Schirmer EC, Gerace L. The nuclear membrane proteome: extending the envelope. Trends in Biochemical Sciences. 30: 551-8. PMID 16125387 DOI: 10.1016/J.Tibs.2005.08.003  0.699
2005 Schirmer EC, Florens L, Guan T, Yates JR, Gerace L. Identification of novel integral membrane proteins of the nuclear envelope with potential disease links using subtractive proteomics. Novartis Foundation Symposium. 264: 63-76; discussion 76. PMID 15773748 DOI: 10.1002/0470093765.Ch6  0.666
2004 Ohba T, Schirmer EC, Nishimoto T, Gerace L. Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore. The Journal of Cell Biology. 167: 1051-62. PMID 15611332 DOI: 10.1083/Jcb.200409149  0.612
2004 Schirmer EC, Gerace L. The stability of the nuclear lamina polymer changes with the composition of lamin subtypes according to their individual binding strengths. The Journal of Biological Chemistry. 279: 42811-7. PMID 15284226 DOI: 10.1074/Jbc.M407705200  0.572
2004 Schirmer EC, Homann OR, Kowal AS, Lindquist S. Dominant gain-of-function mutations in Hsp104p reveal crucial roles for the middle region. Molecular Biology of the Cell. 15: 2061-72. PMID 14978213 DOI: 10.1091/Mbc.E02-08-0502  0.791
2003 Schirmer EC, Yates JR, Gerace L. MudPIT: A powerful proteomics tool for discovery. Discovery Medicine. 3: 38-9. PMID 20704860  0.548
2003 Schirmer EC, Florens L, Guan T, Yates JR, Gerace L. Nuclear membrane proteins with potential disease links found by subtractive proteomics. Science (New York, N.Y.). 301: 1380-2. PMID 12958361 DOI: 10.1126/Science.1088176  0.638
2002 Cashikar AG, Schirmer EC, Hattendorf DA, Glover JR, Ramakrishnan MS, Ware DM, Lindquist SL. Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein. Molecular Cell. 9: 751-60. PMID 11983167 DOI: 10.1016/S1097-2765(02)00499-9  0.782
2002 Schirmer EC, Gerace L. Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope. Genome Biology. 3: REVIEWS1008. PMID 11983061 DOI: 10.1186/Gb-2002-3-4-Reviews1008  0.605
2001 Schirmer EC, Guan T, Gerace L. Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization. The Journal of Cell Biology. 153: 479-89. PMID 11331300 DOI: 10.1083/Jcb.153.3.479  0.65
2001 Schirmer EC, Ware DM, Queitsch C, Kowal AS, Lindquist SL. Subunit interactions influence the biochemical and biological properties of Hsp104. Proceedings of the National Academy of Sciences of the United States of America. 98: 914-9. PMID 11158570 DOI: 10.1073/Pnas.98.3.914  0.673
2000 Guan T, Kehlenbach RH, Schirmer EC, Kehlenbach A, Fan F, Clurman BE, Arnheim N, Gerace L. Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export. Molecular and Cellular Biology. 20: 5619-30. PMID 10891499 DOI: 10.1128/Mcb.20.15.5619-5630.2000  0.779
2000 Saphire AC, Guan T, Schirmer EC, Nemerow GR, Gerace L. Nuclear import of adenovirus DNA in vitro involves the nuclear protein import pathway and hsc70. The Journal of Biological Chemistry. 275: 4298-304. PMID 10660598 DOI: 10.1074/Jbc.275.6.4298  0.636
1998 Lindquist S, DebBurman SK, Glover JR, Kowal AS, Liu JJ, Schirmer EC, Serio TR. Amyloid fibres of Sup35 support a prion-like mechanism of inheritance in yeast. Biochemical Society Transactions. 26: 486-90. PMID 9765901 DOI: 10.1042/Bst0260486  0.76
1998 Schirmer EC, Queitsch C, Kowal AS, Parsell DA, Lindquist S. The ATPase activity of Hsp104, effects of environmental conditions and mutations. The Journal of Biological Chemistry. 273: 15546-52. PMID 9624144 DOI: 10.1074/Jbc.273.25.15546  0.669
1998 Schirmer EC, Lindquist S. Purification And Properties Of Hsp104 From Yeast Methods in Enzymology. 290: 430-444. PMID 9534180 DOI: 10.1016/S0076-6879(98)90036-2  0.516
1997 Schirmer EC, Lindquist S. Interactions of the chaperone Hsp104 with yeast Sup35 and mammalian PrP Proceedings of the National Academy of Sciences of the United States of America. 94: 13932-13937. PMID 9391130 DOI: 10.1073/Pnas.94.25.13932  0.483
1997 Glover JR, Kowal AS, Schirmer EC, Patino MM, Liu JJ, Lindquist S. Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae. Cell. 89: 811-9. PMID 9182769 DOI: 10.1016/S0092-8674(00)80264-0  0.71
1996 Schirmer EC, Glover JR, Singer MA, Lindquist S. HSP100/Clp proteins: a common mechanism explains diverse functions. Trends in Biochemical Sciences. 21: 289-96. PMID 8772382 DOI: 10.1016/0968-0004(96)10038-4  0.622
1994 Schirmer EC, Lindquist S, Vierling E. An Arabidopsis heat shock protein complements a thermotolerance defect in yeast Plant Cell. 6: 1899-1909. PMID 7866032 DOI: 10.1105/Tpc.6.12.1899  0.506
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