| Year |
Citation |
Score |
| 2024 |
Murayama T, Nakayama J, Jiang X, Miyata K, Morris AD, Cai KQ, Prasad RM, Ma X, Efimov A, Belani N, Gerstein ER, Tan Y, Zhou Y, Kim W, Maruyama R, ... ... Chen L, et al. Targeting DHX9 triggers tumor-intrinsic interferon response and replication stress in Small Cell Lung Cancer. Cancer Discovery. PMID 38189443 DOI: 10.1158/2159-8290.CD-23-0486 |
0.708 |
|
| 2023 |
Huda A, Arakawa H, Mazzucco G, Galli M, Petrocelli V, Casola S, Chen L, Doksani Y. The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats. Science Advances. 9: eadf2011. PMID 36947627 DOI: 10.1126/sciadv.adf2011 |
0.755 |
|
| 2022 |
Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Galati A, Palumbo V, et al. TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration. Nucleic Acids Research. PMID 35947650 DOI: 10.1093/nar/gkac659 |
0.625 |
|
| 2021 |
Galati A, Scatolini L, Micheli E, Bavasso F, Cicconi A, Maccallini P, Chen L, Roake CM, Schoeftner S, Artandi SE, Gatti M, Cacchione S, Raffa GD. The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening. Febs Letters. PMID 34817067 DOI: 10.1002/1873-3468.14240 |
0.635 |
|
| 2021 |
Chen L, Chang HY, Artandi SE. Analysis of RNA conformation in endogenously assembled RNPs by icSHAPE. Star Protocols. 2: 100477. PMID 33997809 DOI: 10.1016/j.xpro.2021.100477 |
0.616 |
|
| 2021 |
Vaidyanathan S, Baik R, Chen L, Bravo DT, Suarez CJ, Abazari SM, Salahudeen AA, Dudek AM, Teran CA, Davis TH, Lee CM, Bao G, Randell SH, Artandi SE, Wine JJ, et al. Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33794364 DOI: 10.1016/j.ymthe.2021.03.023 |
0.62 |
|
| 2020 |
Chen L, Bellone RR, Wang Y, Singer-Berk M, Sugasawa K, Ford JM, Artandi SE. A novel DDB2 mutation causes defective recognition of UV-induced DNA damages and prevalent equine squamous cell carcinoma. Dna Repair. 97: 103022. PMID 33276309 DOI: 10.1016/j.dnarep.2020.103022 |
0.624 |
|
| 2020 |
Chen L, Roake CM, Galati A, Bavasso F, Micheli E, Saggio I, Schoeftner S, Cacchione S, Gatti M, Artandi SE, Raffa GD. Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation. Cell Reports. 30: 1358-1372.e5. PMID 32023455 DOI: 10.1016/J.Celrep.2020.01.004 |
0.641 |
|
| 2019 |
Roake CM, Chen L, Chakravarthy AL, Ferrell JE, Raffa GD, Artandi SE. Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease. Molecular Cell. PMID 30930056 DOI: 10.1016/J.Molcel.2019.02.033 |
0.704 |
|
| 2018 |
Chen L, Roake CM, Freund A, Batista PJ, Tian S, Yin YA, Gajera CR, Lin S, Lee B, Pech MF, Venteicher AS, Das R, Chang HY, Artandi SE. An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1. Cell. PMID 29804836 DOI: 10.1016/J.Cell.2018.04.039 |
0.75 |
|
| 2018 |
Lin S, Nascimento EM, Gajera CR, Chen L, Neuhöfer P, Garbuzov A, Wang S, Artandi SE. Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury. Nature. PMID 29618815 DOI: 10.1038/S41586-018-0004-7 |
0.613 |
|
| 2014 |
Wang L, Limbo O, Fei J, Chen L, Kim B, Luo J, Chong J, Conaway RC, Conaway JW, Ranish JA, Kadonaga JT, Russell P, Wang D. Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif. Proceedings of the National Academy of Sciences of the United States of America. 111: 18566-71. PMID 25512493 DOI: 10.1073/Pnas.1420227112 |
0.576 |
|
| 2014 |
Chen L, Ooi SK, Conaway JW, Conaway RC. Biochemical assays for analyzing activities of ATP-dependent chromatin remodeling enzymes Journal of Visualized Experiments. PMID 25407555 DOI: 10.3791/51721 |
0.751 |
|
| 2014 |
Chen L, Ooi SK, Conaway RC, Conaway JW. Generation and purification of human INO80 chromatin remodeling complexes and subcomplexes Journal of Visualized Experiments. PMID 25407439 DOI: 10.3791/51720 |
0.757 |
|
| 2013 |
Chen L, Conaway RC, Conaway JW. Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 20497-502. PMID 24297934 DOI: 10.1073/Pnas.1317092110 |
0.581 |
|
| 2013 |
Sela D, Conkright JJ, Chen L, Gilmore J, Washburn MP, Florens L, Conaway RC, Conaway JW. Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α. The Journal of Biological Chemistry. 288: 26179-87. PMID 23864652 DOI: 10.1074/Jbc.M113.496968 |
0.567 |
|
| 2012 |
Sela D, Chen L, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC. Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes. The Journal of Biological Chemistry. 287: 23035-45. PMID 22577136 DOI: 10.1074/Jbc.M112.369504 |
0.57 |
|
| 2011 |
Chen L, Cai Y, Jin J, Florens L, Swanson SK, Washburn MP, Conaway JW, Conaway RC. Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. The Journal of Biological Chemistry. 286: 11283-9. PMID 21303910 DOI: 10.1074/Jbc.M111.222505 |
0.574 |
|
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