Christian F. Lehner - Publications

Affiliations: 
Universität Zürich, Zürich, ZH, Switzerland 
Area:
cell cycle

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sun MS, Weber J, Blattner AC, Chaurasia S, Lehner CF. MNM and SNM maintain but do not establish achiasmate homolog conjunction during Drosophila male meiosis. Plos Genetics. 15: e1008162. PMID 31136586 DOI: 10.1371/journal.pgen.1008162  0.354
2018 Chaurasia S, Lehner CF. Dynamics and control of sister kinetochore behavior during the meiotic divisions in Drosophila spermatocytes. Plos Genetics. 14: e1007372. PMID 29734336 DOI: 10.1371/journal.pgen.1007372  0.371
2017 Myachina F, Bosshardt F, Bischof J, Kirschmann M, Lehner CF. Drosophila beta-tubulin 97EF is upregulated at low temperature and stabilizes microtubules. Development (Cambridge, England). PMID 29084803 DOI: 10.1242/dev.156109  0.305
2016 Trost M, Blattner AC, Leo S, Lehner CF. Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes. Development (Cambridge, England). 143: 2664-76. PMID 27436041 DOI: 10.1242/dev.134759  0.405
2016 Blattner AC, Chaurasia S, McKee BD, Lehner CF. Separase Is Required for Homolog and Sister Disjunction during Drosophila melanogaster Male Meiosis, but Not for Biorientation of Sister Centromeres. Plos Genetics. 12: e1005996. PMID 27120695 DOI: 10.1371/journal.pgen.1005996  0.38
2016 Trost M, Blattner AC, Lehner CF. Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster. Fly. 0. PMID 27010248 DOI: 10.1080/19336934.2016.1168552  0.384
2016 Blattner AC, Aguilar-Rodríguez J, Kränzlin M, Wagner A, Lehner CF. Drosophila Nnf1 paralogs are partially redundant for somatic and germ line kinetochore function. Chromosoma. PMID 26892014 DOI: 10.1007/S00412-016-0579-4  0.407
2014 Handke B, Szabad J, Lidsky PV, Hafen E, Lehner CF. Towards long term cultivation of Drosophila wing imaginal discs in vitro. Plos One. 9: e107333. PMID 25203426 DOI: 10.1371/Journal.Pone.0107333  0.327
2014 Urban E, Nagarkar-Jaiswal S, Lehner CF, Heidmann SK. The cohesin subunit Rad21 is required for synaptonemal complex maintenance, but not sister chromatid cohesion, during Drosophila female meiosis. Plos Genetics. 10: e1004540. PMID 25101996 DOI: 10.1371/journal.pgen.1004540  0.422
2013 Lidsky PV, Sprenger F, Lehner CF. Distinct modes of centromere protein dynamics during cell cycle progression in Drosophila S2R+ cells. Journal of Cell Science. 126: 4782-93. PMID 23943877 DOI: 10.1242/jcs.134122  0.454
2012 Raychaudhuri N, Dubruille R, Orsi GA, Bagheri HC, Loppin B, Lehner CF. Transgenerational propagation and quantitative maintenance of paternal centromeres depends on Cid/Cenp-A presence in Drosophila sperm. Plos Biology. 10: e1001434. PMID 23300376 DOI: 10.1371/journal.pbio.1001434  0.393
2012 Althoff F, Karess RE, Lehner CF. Spindle checkpoint-independent inhibition of mitotic chromosome segregation by Drosophila Mps1. Molecular Biology of the Cell. 23: 2275-91. PMID 22553353 DOI: 10.1091/mbc.E12-02-0117  0.432
2011 Zielke N, Kim KJ, Tran V, Shibutani ST, Bravo MJ, Nagarajan S, van Straaten M, Woods B, von Dassow G, Rottig C, Lehner CF, Grewal SS, Duronio RJ, Edgar BA. Control of Drosophila endocycles by E2F and CRL4(CDT2). Nature. 480: 123-7. PMID 22037307 DOI: 10.1038/Nature10579  0.687
2010 Schittenhelm RB, Althoff F, Heidmann S, Lehner CF. Detrimental incorporation of excess Cenp-A/Cid and Cenp-C into Drosophila centromeres is prevented by limiting amounts of the bridging factor Cal1. Journal of Cell Science. 123: 3768-79. PMID 20940262 DOI: 10.1242/jcs.067934  0.37
2009 Althoff F, Viktorinová I, Kastl J, Lehner CF. Drosophila Cyclin J is a mitotically stable Cdk1 partner without essential functions. Developmental Biology. 333: 263-72. PMID 19591820 DOI: 10.1016/j.ydbio.2009.06.042  0.506
2009 Schittenhelm RB, Chaleckis R, Lehner CF. Intrakinetochore localization and essential functional domains of Drosophila Spc105. The Embo Journal. 28: 2374-86. PMID 19590494 DOI: 10.1038/emboj.2009.188  0.38
2008 Zielke N, Querings S, Rottig C, Lehner C, Sprenger F. The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles Genes and Development. 22: 1690-1703. PMID 18559483 DOI: 10.1101/gad.469108  0.464
2008 Pauli A, Althoff F, Oliveira RA, Heidmann S, Schuldiner O, Lehner CF, Dickson BJ, Nasmyth K. Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Developmental Cell. 14: 239-51. PMID 18267092 DOI: 10.1016/J.Devcel.2007.12.009  0.397
2007 Pandey R, Heeger S, Lehner CF. Rapid effects of acute anoxia on spindle kinetochore interactions activate the mitotic spindle checkpoint. Journal of Cell Science. 120: 2807-18. PMID 17652159 DOI: 10.1242/jcs.007690  0.418
2007 Schittenhelm RB, Heeger S, Althoff F, Walter A, Heidmann S, Mechtler K, Lehner CF. Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes. Chromosoma. 116: 385-402. PMID 17333235 DOI: 10.1007/S00412-007-0103-Y  0.373
2007 Schuh M, Lehner CF, Heidmann S. Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase. Current Biology : Cb. 17: 237-43. PMID 17222555 DOI: 10.1016/J.Cub.2006.11.051  0.381
2006 Reber A, Lehner CF, Jacobs HW. Terminal mitoses require negative regulation of Fzr/Cdh1 by Cyclin A, preventing premature degradation of mitotic cyclins and String/Cdc25. Development (Cambridge, England). 133: 3201-11. PMID 16854973 DOI: 10.1242/dev.02488  0.57
2005 Heeger S, Leismann O, Schittenhelm R, Schraidt O, Heidmann S, Lehner CF. Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog. Genes & Development. 19: 2041-53. PMID 16140985 DOI: 10.1101/Gad.347805  0.422
2005 Pandey R, Heidmann S, Lehner CF. Epithelial re-organization and dynamics of progression through mitosis in Drosophila separase complex mutants. Journal of Cell Science. 118: 733-42. PMID 15671062 DOI: 10.1242/Jcs.01663  0.467
2004 Fischer MG, Heeger S, Häcker U, Lehner CF. The mitotic arrest in response to hypoxia and of polar bodies during early embryogenesis requires Drosophila Mps1. Current Biology : Cb. 14: 2019-24. PMID 15556864 DOI: 10.1016/J.Cub.2004.11.008  0.495
2004 Emmerich J, Meyer CA, de la Cruz AF, Edgar BA, Lehner CF. Cyclin D does not provide essential Cdk4-independent functions in Drosophila. Genetics. 168: 867-75. PMID 15514060 DOI: 10.1534/genetics.104.027417  0.667
2004 Heidmann D, Horn S, Heidmann S, Schleiffer A, Nasmyth K, Lehner CF. The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions. Chromosoma. 113: 177-87. PMID 15375666 DOI: 10.1007/S00412-004-0305-5  0.343
2004 Jäger H, Herzig B, Herzig A, Sticht H, Lehner CF, Heidmann S. Structure predictions and interaction studies indicate homology of separase N-terminal regulatory domains and Drosophila THR. Cell Cycle (Georgetown, Tex.). 3: 182-8. PMID 14712087 DOI: 10.4161/Cc.3.2.605  0.682
2003 Leismann O, Lehner CF. Drosophila securin destruction involves a D-box and a KEN-box and promotes anaphase in parallel with Cyclin A degradation. Journal of Cell Science. 116: 2453-60. PMID 12724352 DOI: 10.1242/jcs.00411  0.449
2002 Herzig A, Lehner CF, Heidmann S. Proteolytic cleavage of the THR subunit during anaphase limits Drosophila separase function. Genes & Development. 16: 2443-54. PMID 12231632 DOI: 10.1101/Gad.242202  0.727
2002 Jacobs HW, Richter DO, Venkatesh TR, Lehner CF. Completion of mitosis requires neither fzr/rap nor fzr2, a male germline-specific Drosophila Cdh1 homolog Current Biology. 12: 1435-1441. PMID 12194827 DOI: 10.1016/S0960-9822(02)01074-6  0.53
2002 Meyer CA, Jacobs HW, Lehner CF. Cyclin D-cdk4 is not a master regulator of cell multiplication in Drosophila embryos. Current Biology : Cb. 12: 661-6. PMID 11967154 DOI: 10.1016/S0960-9822(02)00770-4  0.509
2002 Meyer CA, Kramer I, Dittrich R, Marzodko S, Emmerich J, Lehner CF. Drosophila p27Dacapo expression during embryogenesis is controlled by a complex regulatory region independent of cell cycle progression. Development (Cambridge, England). 129: 319-28. PMID 11807025  0.402
2001 Heidmann D, Lehner CF. Reduction of Cre recombinase toxicity in proliferating Drosophila cells by estrogen-dependent activity regulation. Development Genes and Evolution. 211: 458-65. PMID 11685583 DOI: 10.1007/s004270100167  0.368
2001 Jäger H, Herzig A, Lehner CF, Heidmann S. Drosophila separase is required for sister chromatid separation and binds to PIM and THR. Genes & Development. 15: 2572-84. PMID 11581162 DOI: 10.1101/Gad.207301  0.726
2001 Lehner CF, Jacobs HW, Sauer K, Meyer CA. Regulation of the embryonic cell proliferation by Drosophila cyclin D and cyclin E complexes. Novartis Foundation Symposium. 237: 43-54; discussion 54. PMID 11444049 DOI: 10.1002/0470846666.Ch5  0.693
2001 Jacobs HW, Keidel E, Lehner CF. A complex degradation signal in Cyclin A required for G1 arrest, and a C-terminal region for mitosis. The Embo Journal. 20: 2376-86. PMID 11350926 DOI: 10.1093/emboj/20.10.2376  0.539
2000 Leismann O, Herzig A, Heidmann S, Lehner CF. Degradation of Drosophila PIM regulates sister chromatid separation during mitosis. Genes & Development. 14: 2192-205. PMID 10970883 DOI: 10.1101/Gad.176700  0.755
2000 Datar SA, Jacobs HW, de la Cruz AF, Lehner CF, Edgar BA. The Drosophila cyclin D-Cdk4 complex promotes cellular growth. The Embo Journal. 19: 4543-54. PMID 10970848 DOI: 10.1093/emboj/19.17.4543  0.675
2000 Meyer CA, Jacobs HW, Datar SA, Du W, Edgar BA, Lehner CF. Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression. The Embo Journal. 19: 4533-42. PMID 10970847 DOI: 10.1093/Emboj/19.17.4533  0.682
2000 Lane ME, Elend M, Heidmann D, Herr A, Marzodko S, Herzig A, Lehner CF. A screen for modifiers of cyclin E function in Drosophila melanogaster identifies Cdk2 mutations, revealing the insignificance of putative phosphorylation sites in Cdk2. Genetics. 155: 233-44. PMID 10790398  0.731
1998 Jacobs HW, Knoblich JA, Lehner CF. Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B. Genes & Development. 12: 3741-51. PMID 9851980 DOI: 10.1101/Gad.12.23.3741  0.646
1998 Jacobs H, Stratmann R, Lehner CF. A screen for lethal mutations in the chromosomal region 59AB suggests that bellwether encodes the alpha subunit of the mitochondrial ATP synthase in Drosophila melanogaster Molecular and General Genetics. 259: 383-387. PMID 9790593 DOI: 10.1007/s004380050826  0.318
1998 Lorca T, Castro A, Martinez AM, Vigneron S, Morin N, Sigrist S, Lehner C, Dorée M, Labbé JC. Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts. The Embo Journal. 17: 3565-75. PMID 9649427 DOI: 10.1093/Emboj/17.13.3565  0.637
1998 Weiss A, Herzig A, Jacobs H, Lehner CF. Continuous Cyclin E expression inhibits progression through endoreduplication cycles in Drosophila. Current Biology : Cb. 8: 239-42. PMID 9501988 DOI: 10.1016/S0960-9822(98)70090-9  0.753
1997 Weigmann K, Cohen SM, Lehner CF. Cell cycle progression, growth and patterning in imaginal discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase. Development (Cambridge, England). 124: 3555-63. PMID 9342048  0.324
1997 Sigrist SJ, Lehner CF. Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. Cell. 90: 671-81. PMID 9288747 DOI: 10.1016/S0092-8674(00)80528-0  0.684
1997 Thomas BJ, Zavitz KH, Dong X, Lane ME, Weigmann K, Finley RL, Brent R, Lehner CF, Zipursky SL. roughex down-regulates G2 cyclins in G1. Genes & Development. 11: 1289-98. PMID 9171373 DOI: 10.1101/Gad.11.10.1289  0.465
1997 Lehner CF, Lane ME. Cell cycle regulators in Drosophila: downstream and part of developmental decisions. Journal of Cell Science. 110: 523-8. PMID 9092934  0.383
1996 Lane ME, Sauer K, Wallace K, Jan YN, Lehner CF, Vaessin H. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell. 87: 1225-35. PMID 8980229 DOI: 10.1016/S0092-8674(00)81818-8  0.745
1996 Edgar BA, Lehner CF. Developmental control of cell cycle regulators: a fly's perspective. Science (New York, N.Y.). 274: 1646-52. PMID 8939845 DOI: 10.1126/science.274.5293.1646  0.651
1996 Sauer K, Weigmann K, Sigrist S, Lehner CF. Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase. Molecular Biology of the Cell. 7: 1759-69. PMID 8930898 DOI: 10.1091/Mbc.7.11.1759  0.717
1996 Stratmann R, Lehner CF. Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition. Cell. 84: 25-35. PMID 8548823 DOI: 10.1016/S0092-8674(00)80990-3  0.462
1995 Sauer K, Lehner CF. The role of cyclin E in the regulation of entry into S phase. Progress in Cell Cycle Research. 1: 125-39. PMID 9552358 DOI: 10.1007/978-1-4615-1809-9_10  0.665
1995 Weigmann K, Lehner CF. Cell fate specification by even-skipped expression in the Drosophila nervous system is coupled to cell cycle progression. Development (Cambridge, England). 121: 3713-21. PMID 8582283  0.359
1995 Sigrist S, Ried G, Lehner CF. Dmcdc2 kinase is required for both meiotic divisions during Drosophila spermatogenesis and is activated by the Twine/cdc25 phosphatase. Mechanisms of Development. 53: 247-60. PMID 8562426 DOI: 10.1016/0925-4773(95)00441-3  0.627
1995 Sauer K, Knoblich JA, Richardson H, Lehner CF. Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes & Development. 9: 1327-39. PMID 7797073 DOI: 10.1101/Gad.9.11.1327  0.767
1995 Sigrist S, Jacobs H, Stratmann R, Lehner CF. Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. The Embo Journal. 14: 4827-38. PMID 7588612 DOI: 10.1002/J.1460-2075.1995.Tb00164.X  0.667
1995 Kreutzer MA, Richards JP, De Silva-Udawatta MN, Temenak JJ, Knoblich JA, Lehner CF, Bennett KL. Caenorhabditis elegans cyclin A- and B-type genes: a cyclin A multigene family, an ancestral cyclin B3 and differential germline expression. Journal of Cell Science. 108: 2415-24. PMID 7545687  0.598
1994 Knoblich JA, Sauer K, Jones L, Richardson H, Saint R, Lehner CF. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell. 77: 107-20. PMID 8156587 DOI: 10.1016/0092-8674(94)90239-9  0.804
1993 Knoblich JA, Lehner CF. Synergistic action of Drosophila cyclins A and B during the G2-M transition. The Embo Journal. 12: 65-74. PMID 8428595 DOI: 10.1002/J.1460-2075.1993.Tb05632.X  0.767
1993 D'Andrea RJ, Stratmann R, Lehner CF, John UP, Saint R. The three rows gene of Drosophila melanogaster encodes a novel protein that is required for chromosome disjunction during mitosis. Molecular Biology of the Cell. 4: 1161-74. PMID 8305737 DOI: 10.1091/Mbc.4.11.1161  0.363
1993 Stern B, Ried G, Clegg NJ, Grigliatti TA, Lehner CF. Genetic analysis of the Drosophila cdc2 homolog. Development (Cambridge, England). 117: 219-32. PMID 8223248  0.42
1992 Lehner CF. The pebble gene is required for cytokinesis in Drosophila. Journal of Cell Science. 103: 1021-30. PMID 1487486  0.371
1992 Lehner CF, Ried G, Stern B, Knoblich JA. Cyclins and cdc2 kinases in Drosophila: genetic analyses in a higher eukaryote. Ciba Foundation Symposium. 170: 97-109; discussion 1. PMID 1483353  0.661
1992 Courtot C, Fankhauser C, Simanis V, Lehner CF. The Drosophila cdc25 homolog twine is required for meiosis. Development (Cambridge, England). 116: 405-16. PMID 1286615  0.309
1991 Lehner CF. Pulling the string: cell cycle regulation during Drosophila development. Seminars in Cell Biology. 2: 223-31. PMID 1842341  0.393
1991 Lehner CF, Yakubovich N, O'Farrell PH. Exploring the role of Drosophila cyclin A in the regulation of S phase. Cold Spring Harbor Symposia On Quantitative Biology. 56: 465-75. PMID 1840259 DOI: 10.1101/Sqb.1991.056.01.053  0.644
1990 Lehner CF, O'Farrell PH. The roles of Drosophila cyclins A and B in mitotic control. Cell. 61: 535-47. PMID 2139805 DOI: 10.1016/0092-8674(90)90535-M  0.696
1990 Lehner CF, O'Farrell PH. Drosophila cdc2 homologs: a functional homolog is coexpressed with a cognate variant. The Embo Journal. 9: 3573-81. PMID 2120045 DOI: 10.1002/J.1460-2075.1990.Tb07568.X  0.688
1989 Borer RA, Lehner CF, Eppenberger HM, Nigg EA. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell. 56: 379-90. PMID 2914325 DOI: 10.1016/0092-8674(89)90241-9  0.335
1989 Peter M, Kitten GT, Lehner CF, Vorburger K, Bailer SM, Maridor G, Nigg EA. Cloning and sequencing of cDNA clones encoding chicken lamins A and B1 and comparison of the primary structures of vertebrate A- and B-type lamins. Journal of Molecular Biology. 208: 393-404. PMID 2795656 DOI: 10.1016/0022-2836(89)90504-4  0.339
1989 O'Farrell PH, Edgar BA, Lakich D, Lehner CF. Directing cell division during development. Science (New York, N.Y.). 246: 635-40. PMID 2683080 DOI: 10.1126/Science.2683080  0.723
1989 Lehner CF, O'Farrell PH. Expression and function of Drosophila cyclin A during embryonic cell cycle progression. Cell. 56: 957-68. PMID 2564316 DOI: 10.1016/0092-8674(89)90629-6  0.726
1989 Vorburger K, Lehner CF, Kitten GT, Eppenberger HM, Nigg EA. A second higher vertebrate B-type lamin. cDNA sequence determination and in vitro processing of chicken lamin B2. Journal of Molecular Biology. 208: 405-15. PMID 2477550 DOI: 10.1016/0022-2836(89)90505-6  0.336
1986 Lehner CF, Fürstenberger G, Eppenberger HM, Nigg EA. Biogenesis of the nuclear lamina: in vivo synthesis and processing of nuclear protein precursors. Proceedings of the National Academy of Sciences of the United States of America. 83: 2096-9. PMID 3515346 DOI: 10.1073/Pnas.83.7.2096  0.346
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