Karl W. Broman - Publications

Affiliations: 
Statistics University of Wisconsin, Madison, Madison, WI 
Area:
Statistics, Genetics

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yoshihara T, Miller ND, Rabanal FA, Myles H, Kwak IY, Broman KW, Sadkhin B, Baxter I, Dilkes BP, Hudson ME, Spalding EP. Leveraging orthology within maize and Arabidopsis QTL to identify genes affecting natural variation in gravitropism. Proceedings of the National Academy of Sciences of the United States of America. 119: e2212199119. PMID 36161933 DOI: 10.1073/pnas.2212199119  0.614
2022 Vincent M, Gerdes Gyuricza I, Keele GR, Gatti DM, Keller MP, Broman KW, Churchill GA. QTLViewer: An interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations. G3 (Bethesda, Md.). PMID 35703938 DOI: 10.1093/g3journal/jkac146  0.36
2021 Tran Q, Broman KW. Treatment of the X chromosome in mapping multiple quantitative trait loci. G3 (Bethesda, Md.). 11. PMID 33604671 DOI: 10.1093/g3journal/jkab005  0.303
2020 Schwerbel K, Kamitz A, Krahmer N, Hallahan N, Jähnert M, Gottmann P, Lebek S, Schallschmidt T, Arends D, Schumacher F, Kleuser B, Haltenhof T, Heyd F, Gancheva S, Broman KW, et al. Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation. Journal of Hepatology. PMID 32376415 DOI: 10.1016/J.Jhep.2020.04.031  0.392
2020 Rodriguez-Gil JL, Watkins-Chow DE, Baxter LL, Elliot G, Harper UL, Wincovitch SM, Wedel JC, Incao AA, Huebecker M, Boehm FJ, Garver WS, Porter FD, Broman KW, Platt FM, Pavan WJ. Genetic background modifies phenotypic severity and longevity in a mouse model of Niemann-Pick disease type C1. Disease Models & Mechanisms. PMID 31996359 DOI: 10.1242/Dmm.042614  0.415
2019 Boehm FJ, Chesler EJ, Yandell BS, Broman KW. Testing Pleiotropy vs. Separate QTL in Multiparental Populations. G3 (Bethesda, Md.). 9: 2317-2324. PMID 33877348 DOI: 10.1534/g3.119.400098  0.359
2019 Boehm F, Yandell B, Broman KW. qtl2pleio: Testing pleiotropy vs. separate QTL in multiparental populations. Journal of Open Source Software. 4. PMID 32715273 DOI: 10.21105/Joss.01435  0.441
2019 Kemis JH, Linke V, Barrett KL, Boehm FJ, Traeger LL, Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Churchill GA, Amador-Noguez D, Russell JD, Yandell BS, Broman KW, et al. Genetic determinants of gut microbiota composition and bile acid profiles in mice. Plos Genetics. 15: e1008073. PMID 31465442 DOI: 10.1371/Journal.Pgen.1008073  0.408
2019 Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Vincent M, Mitok KA, Wang Z, Ishimura T, Simonett SP, Emfinger CH, Das R, Beck T, Kendziorski C, Broman KW, et al. Gene loci associated with insulin secretion in islets from non-diabetic mice. The Journal of Clinical Investigation. 130. PMID 31343992 DOI: 10.1172/Jci129143  0.328
2019 Boehm FJ, Chesler EJ, Yandell BS, Broman KW. Testing Pleiotropy Separate QTL in Multiparental Populations. G3 (Bethesda, Md.). PMID 31092608 DOI: 10.1534/G3.119.400098  0.456
2019 Broman KW, Gatti DM, Svenson KL, Sen Ś, Churchill GA. Cleaning Genotype Data from Diversity Outbred Mice. G3 (Bethesda, Md.). PMID 30877082 DOI: 10.1534/G3.119.400165  0.436
2018 Broman KW, Gatti DM, Simecek P, Furlotte NA, Prins P, Sen Ś, Yandell BS, Churchill GA. R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multi-parent Populations. Genetics. PMID 30591514 DOI: 10.1534/Genetics.118.301595  0.39
2018 Palus M, Sohrabi Y, Broman KW, Strnad H, Šíma M, Růžek D, Volkova V, Slapničková M, Vojtíšková J, Mrázková L, Salát J, Lipoldová M. A novel locus on mouse chromosome 7 that influences survival after infection with tick-borne encephalitis virus. Bmc Neuroscience. 19: 39. PMID 29976152 DOI: 10.1186/S12868-018-0438-8  0.352
2018 Keller MP, Gatti DM, Schueler KL, Rabaglia ME, Stapleton DS, Simecek P, Vincent M, Allen S, Broman AT, Bacher R, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD. Genetic Drivers of Pancreatic Islet Function. Genetics. PMID 29567659 DOI: 10.1534/Genetics.118.300864  0.371
2017 Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, et al. Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats. Obesity (Silver Spring, Md.). PMID 29193816 DOI: 10.1002/Oby.22075  0.419
2016 Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, ... ... Broman KW, et al. The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets. Plos Genetics. 12: e1006466. PMID 27935966 DOI: 10.1371/Journal.Pgen.1006466  0.332
2016 Wang RJ, Gray MM, Parmenter MD, Broman KW, Payseur BA. Recombination rate variation in mice from an isolated island. Molecular Ecology. PMID 27864900 DOI: 10.1111/Mec.13932  0.436
2016 Parmenter MD, Gray MM, Hogan CA, Ford IN, Broman KW, Vinyard CJ, Payseur BA. Genetics of Skeletal Evolution in Unusually Large Mice from Gough Island. Genetics. PMID 27694627 DOI: 10.1534/Genetics.116.193805  0.457
2016 Zigler JS, Hodgkinson CA, Wright M, Klise A, Sundin O, Broman KW, Hejtmancik F, Huang H, Patek B, Sergeev Y, Hose S, Brayton C, Xaiodong J, Vasquez D, Maragakis N, et al. A Spontaneous Missense Mutation in Branched Chain Keto Acid Dehydrogenase Kinase in the Rat Affects Both the Central and Peripheral Nervous Systems. Plos One. 11: e0160447. PMID 27472223 DOI: 10.1371/Journal.Pone.0160447  0.301
2016 De Simone M, Spagnuolo L, Lorè NI, Cigana C, De Fino I, Broman KW, Iraqi FA, Bragonzi A. Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice. Bmc Genomics. 17: 351. PMID 27169516 DOI: 10.1186/S12864-016-2676-4  0.317
2016 Tian J, Keller MP, Broman AT, Kendziorski C, Yandell BS, Attie AD, Broman KW. The Dissection of Expression Quantitative Trait Locus Hotspots. Genetics. 202: 1563-74. PMID 26837753 DOI: 10.1534/Genetics.115.183624  0.434
2015 Kwak IY, Moore CR, Spalding EP, Broman KW. Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-trait Mapping. G3 (Bethesda, Md.). PMID 26530421 DOI: 10.1534/G3.115.024133  0.66
2015 Tian J, Keller MP, Oler AT, Rabaglia ME, Schueler KL, Stapleton DS, Broman AT, Zhao W, Kendziorski C, Yandell BS, Hagenbuch B, Broman KW, Attie AD. Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets. Genetics. 201: 1253-62. PMID 26385979 DOI: 10.1534/Genetics.115.179432  0.412
2015 Broman KW, Keller MP, Broman AT, Kendziorski C, Yandell BS, Sen Ś, Attie AD. Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study. G3 (Bethesda, Md.). 5: 2177-86. PMID 26290572 DOI: 10.1534/G3.115.019778  0.386
2015 Gray MM, Parmenter M, Hogan C, Ford I, Cuthbert RJ, Ryan PG, Broman KW, Payseur BA. Genetics of Rapid and Extreme Size Evolution in Island Mice. Genetics. PMID 26199233 DOI: 10.1534/Genetics.115.177790  0.39
2015 Broman KW. R/qtlcharts: interactive graphics for quantitative trait locus mapping. Genetics. 199: 359-61. PMID 25527287 DOI: 10.1534/Genetics.114.172742  0.352
2015 Whitney KD, Broman KW, Kane NC, Hovick SM, Randell RA, Rieseberg LH. Quantitative trait locus mapping identifies candidate alleles involved in adaptive introgression and range expansion in a wild sunflower. Molecular Ecology. 24: 2194-211. PMID 25522096 DOI: 10.1111/Mec.13044  0.464
2014 Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA. Quantitative trait locus mapping methods for diversity outbred mice. G3 (Bethesda, Md.). 4: 1623-33. PMID 25237114 DOI: 10.1534/G3.114.013748  0.5
2014 Rowsey R, Gruhn J, Broman KW, Hunt PA, Hassold T. Examining variation in recombination levels in the human female: a test of the production-line hypothesis. American Journal of Human Genetics. 95: 108-12. PMID 24995869 DOI: 10.1097/Ogx.0000000000000135  0.301
2014 Street VA, Kujawa SG, Manichaikul A, Broman KW, Kallman JC, Shilling DJ, Iwata AJ, Robinson LC, Robbins CA, Li J, Liberman MC, Tempel BL. Resistance to noise-induced hearing loss in 129S6 and MOLF mice: identification of independent, overlapping, and interacting chromosomal regions. Journal of the Association For Research in Otolaryngology : Jaro. 15: 721-38. PMID 24952082 DOI: 10.1007/S10162-014-0472-X  0.55
2014 Kwak IY, Moore CR, Spalding EP, Broman KW. A simple regression-based method to map quantitative trait loci underlying function-valued phenotypes. Genetics. 197: 1409-16. PMID 24931408 DOI: 10.1534/Genetics.114.166306  0.659
2014 Huang BE, Raghavan C, Mauleon R, Broman KW, Leung H. Efficient imputation of missing markers in low-coverage genotyping-by-sequencing data from multiparental crosses. Genetics. 197: 401-4. PMID 24583583 DOI: 10.1534/Genetics.113.158014  0.337
2014 Baier B, Hunt P, Broman KW, Hassold T. Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males. Plos Genetics. 10: e1004125. PMID 24497841 DOI: 10.1371/Journal.Pgen.1004125  0.378
2013 Bautz DJ, Broman KW, Threadgill DW. Identification of a novel polymorphism in X-linked sterol-4-alpha-carboxylate 3-dehydrogenase (Nsdhl) associated with reduced high-density lipoprotein cholesterol levels in I/LnJ mice. G3 (Bethesda, Md.). 3: 1819-25. PMID 23979938 DOI: 10.1534/G3.113.007567  0.329
2013 Moore CR, Johnson LS, Kwak IY, Livny M, Broman KW, Spalding EP. High-throughput computer vision introduces the time axis to a quantitative trait map of a plant growth response. Genetics. 195: 1077-86. PMID 23979570 DOI: 10.1534/Genetics.113.153346  0.665
2012 Galvan A, Colombo F, Noci S, Pazzaglia S, Mancuso M, Manenti G, Broman KW, Saran A, Dragani TA. The Lsktm1 locus modulates lung and skin tumorigenesis in the mouse. G3 (Bethesda, Md.). 2: 1041-6. PMID 22973541 DOI: 10.1534/G3.112.003525  0.33
2012 Broman KW, Kim S, Sen S, Ané C, Payseur BA. Mapping quantitative trait loci onto a phylogenetic tree. Genetics. 192: 267-79. PMID 22745229 DOI: 10.1534/Genetics.112.142448  0.472
2012 Neto EC, Keller MP, Broman AF, Attie AD, Jansen RC, Broman KW, Yandell BS. Quantile-based permutation thresholds for quantitative trait loci hotspots. Genetics. 191: 1355-65. PMID 22661325 DOI: 10.1534/Genetics.112.139451  0.446
2012 Wang CY, Stapleton DS, Schueler KL, Rabaglia ME, Oler AT, Keller MP, Kendziorski CM, Broman KW, Yandell BS, Schadt EE, Attie AD. Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis. Journal of Lipid Research. 53: 1493-501. PMID 22628617 DOI: 10.1194/Jlr.M025239  0.388
2012 King EG, Merkes CM, McNeil CL, Hoofer SR, Sen S, Broman KW, Long AD, Macdonald SJ. Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource. Genome Research. 22: 1558-66. PMID 22496517 DOI: 10.1101/Gr.134031.111  0.488
2012 Broman KW. Haplotype probabilities in advanced intercross populations. G3 (Bethesda, Md.). 2: 199-202. PMID 22384398 DOI: 10.1534/G3.111.001818  0.42
2012 Broman KW. Genotype probabilities at intermediate generations in the construction of recombinant inbred lines. Genetics. 190: 403-12. PMID 22345609 DOI: 10.1534/Genetics.111.132647  0.422
2012 Arends D, van der Velde KJ, Prins P, Broman KW, Möller S, Jansen RC, Swertz MA. xQTL workbench: a scalable web environment for multi-level QTL analysis. Bioinformatics (Oxford, England). 28: 1042-4. PMID 22308096 DOI: 10.1093/Bioinformatics/Bts049  0.377
2012 Amlin-Van Schaick JC, Kim S, DiFabio C, Lee MH, Broman KW, Reilly KM. Arlm1 is a male-specific modifier of astrocytoma resistance on mouse Chr 12. Neuro-Oncology. 14: 160-74. PMID 22234937 DOI: 10.1093/Neuonc/Nor206  0.363
2012 Davis RC, van Nas A, Castellani LW, Zhao Y, Zhou Z, Wen P, Yu S, Qi H, Rosales M, Schadt EE, Broman KW, Péterfy M, Lusis AJ. Systems genetics of susceptibility to obesity-induced diabetes in mice. Physiological Genomics. 44: 1-13. PMID 22010005 DOI: 10.1152/Physiolgenomics.00003.2011  0.369
2011 Bradley KM, Breyer JP, Melville DB, Broman KW, Knapik EW, Smith JR. An SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci. G3 (Bethesda, Md.). 1: 3-9. PMID 21949597 DOI: 10.1534/G3.111.000190  0.479
2011 Moreland AJ, Guethlein LA, Reeves RK, Broman KW, Johnson RP, Parham P, O'Connor DH, Bimber BN. Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques. Bmc Genomics. 12: 295. PMID 21645414 DOI: 10.1186/1471-2164-12-295  0.314
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, ... ... Broman KW, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/Gr.111310.110  0.502
2011 Svetec N, Werzner A, Wilches R, Pavlidis P, Alvarez-Castro JM, Broman KW, Metzler D, Stephan W. Identification of X-linked quantitative trait loci affecting cold tolerance in Drosophila melanogaster and fine mapping by selective sweep analysis. Molecular Ecology. 20: 530-44. PMID 21199023 DOI: 10.1111/J.1365-294X.2010.04951.X  0.492
2010 Billings T, Sargent EE, Szatkiewicz JP, Leahy N, Kwak IY, Bektassova N, Walker M, Hassold T, Graber JH, Broman KW, Petkov PM. Patterns of recombination activity on mouse chromosome 11 revealed by high resolution mapping. Plos One. 5: e15340. PMID 21170346 DOI: 10.1371/Journal.Pone.0015340  0.66
2010 Murdoch B, Owen N, Shirley S, Crumb S, Broman KW, Hassold T. Multiple loci contribute to genome-wide recombination levels in male mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 550-5. PMID 21113599 DOI: 10.1007/S00335-010-9303-5  0.452
2010 Arends D, Prins P, Jansen RC, Broman KW. R/qtl: high-throughput multiple QTL mapping. Bioinformatics (Oxford, England). 26: 2990-2. PMID 20966004 DOI: 10.1093/Bioinformatics/Btq565  0.413
2010 Jurisic G, Sundberg JP, Bleich A, Leiter EH, Broman KW, Buechler G, Alley L, Vestweber D, Detmar M. Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease Genes and Immunity. 11: 219-231. PMID 20220769 DOI: 10.1038/Gene.2010.4  0.395
2010 Burrage LC, Baskin-Hill AE, Sinasac DS, Singer JB, Croniger CM, Kirby A, Kulbokas EJ, Daly MJ, Lander ES, Broman KW, Nadeau JH. Genetic resistance to diet-induced obesity in chromosome substitution strains of mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 115-29. PMID 20127486 DOI: 10.1007/S00335-010-9247-9  0.377
2010 Wong AK, Ruhe AL, Dumont BL, Robertson KR, Guerrero G, Shull SM, Ziegle JS, Millon LV, Broman KW, Payseur BA, Neff MW. A comprehensive linkage map of the dog genome. Genetics. 184: 595-605. PMID 19966068 DOI: 10.1534/Genetics.109.106831  0.421
2010 Manichaikul A, Moon JY, Sen S, Yandell BS, Broman KW. A model selection approach for the identification of quantitative trait loci in experimental crosses, allowing epistasis (Genetics 181 (1077-1086)) Genetics. 184: 607. DOI: 10.1534/Genetics.109.112912  0.604
2009 Shavit JA, Manichaikul A, Lemmerhirt HL, Broman KW, Ginsburg D. Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice. Blood. 114: 5368-74. PMID 19789385 DOI: 10.1182/Blood-2009-07-233213  0.583
2009 Cheng EY, Hunt PA, Naluai-Cecchini TA, Fligner CL, Fujimoto VY, Pasternack TL, Schwartz JM, Steinauer JE, Woodruff TJ, Cherry SM, Hansen TA, Vallente RU, Broman KW, Hassold TJ. Meiotic recombination in human oocytes. Plos Genetics. 5: e1000661. PMID 19763179 DOI: 10.1371/Journal.Pgen.1000661  0.365
2009 Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G, Przeworski M. Broad-scale recombination patterns underlying proper disjunction in humans. Plos Genetics. 5: e1000658. PMID 19763175 DOI: 10.1371/Journal.Pgen.1000658  0.349
2009 Dumont BL, Broman KW, Payseur BA. Variation in genomic recombination rates among heterogeneous stock mice. Genetics. 182: 1345-9. PMID 19535547 DOI: 10.1534/Genetics.109.105114  0.407
2009 Cox A, Ackert-Bicknell CL, Dumont BL, Ding Y, Bell JT, Brockmann GA, Wergedal JE, Bult C, Paigen B, Flint J, Tsaih SW, Churchill GA, Broman KW. A new standard genetic map for the laboratory mouse. Genetics. 182: 1335-44. PMID 19535546 DOI: 10.1534/Genetics.109.105486  0.484
2009 Venkatesan M, Broman KW, Sellers M, Rasgon JL. An initial linkage map of the West Nile Virus vector Culex tarsalis Insect Molecular Biology. 18: 453-463. PMID 19453767 DOI: 10.1111/J.1365-2583.2009.00885.X  0.453
2009 Manichaikul A, Broman KW. Binary trait mapping in experimental crosses with selective genotyping. Genetics. 182: 863-74. PMID 19416941 DOI: 10.1534/Genetics.108.098913  0.631
2009 Sen S, Johannes F, Broman KW. Selective genotyping and phenotyping strategies in a complex trait context. Genetics. 181: 1613-26. PMID 19153260 DOI: 10.1534/Genetics.108.094607  0.413
2009 Manichaikul A, Moon JY, Sen S, Yandell BS, Broman KW. A model selection approach for the identification of quantitative trait loci in experimental crosses, allowing epistasis. Genetics. 181: 1077-86. PMID 19104078 DOI: 10.1534/Genetics.108.094565  0.585
2008 Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, Daly MJ, Broman KW, Lander ES, Nadeau JH. Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 19910-4. PMID 19066216 DOI: 10.1073/Pnas.0810388105  0.48
2008 Paigen K, Szatkiewicz JP, Sawyer K, Leahy N, Parvanov ED, Ng SH, Graber JH, Broman KW, Petkov PM. The recombinational anatomy of a mouse chromosome. Plos Genetics. 4: e1000119. PMID 18617997 DOI: 10.1371/Journal.Pgen.1000119  0.418
2008 Hill MM, Broman KW, Stupka E, Smith WC, Jiang D, Sidow A. The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution. Genome Research. 18: 1369-79. PMID 18519652 DOI: 10.1101/Gr.078576.108  0.433
2008 Peirce JL, Broman KW, Lu L, Chesler EJ, Zhou G, Airey DC, Birmingham AE, Williams RW. Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis. Plos One. 3: e1977. PMID 18431467 DOI: 10.1371/Journal.Pone.0001977  0.394
2008 Bjornsson HT, Albert TJ, Ladd-Acosta CM, Green RD, Rongione MA, Middle CM, Irizarry RA, Broman KW, Feinberg AP. SNP-specific array-based allele-specific expression analysis. Genome Research. 18: 771-9. PMID 18369178 DOI: 10.1101/Gr.073254.107  0.344
2008 Roy-Gagnon MH, Mathias RA, Fallin MD, Jee SH, Broman KW, Wilson AF. An extension of the regression of offspring on mid-parent to test for association and estimate locus-specific heritability: the revised ROMP method. Annals of Human Genetics. 72: 115-25. PMID 18042270 DOI: 10.1111/J.1469-1809.2007.00401.X  0.363
2007 Petkov PM, Broman KW, Szatkiewicz JP, Paigen K. Crossover interference underlies sex differences in recombination rates. Trends in Genetics : Tig. 23: 539-42. PMID 17964681 DOI: 10.1016/J.Tig.2007.08.015  0.323
2007 Peirce JL, Broman KW, Lu L, Williams RW. A simple method for combining genetic mapping data from multiple crosses and experimental designs. Plos One. 2: e1036. PMID 17940600 DOI: 10.1371/Journal.Pone.0001036  0.47
2007 Manichaikul A, Palmer AA, Sen S, Broman KW. Significance thresholds for quantitative trait locus mapping under selective genotyping. Genetics. 177: 1963-6. PMID 17720902 DOI: 10.1534/Genetics.107.080093  0.625
2007 Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT. Spectrum of heart disease associated with murine and human GATA4 mutation. Journal of Molecular and Cellular Cardiology. 43: 677-85. PMID 17643447 DOI: 10.1016/J.Yjmcc.2007.06.004  0.532
2007 Sen S, Satagopan JM, Broman KW, Churchill GA. R/qtlDesign: Inbred line cross experimental design Mammalian Genome. 18: 87-93. PMID 17347894 DOI: 10.1007/S00335-006-0090-Y  0.355
2007 Lemmerhirt HL, Broman KW, Shavit JA, Ginsburg D. Genetic regulation of plasma von Willebrand factor levels: Quantitative trait loci analysis in a mouse model Journal of Thrombosis and Haemostasis. 5: 329-335. PMID 17155961 DOI: 10.1111/J.1538-7836.2007.02325.X  0.488
2007 Teuscher F, Broman KW. Haplotype probabilities for multiple-strain recombinant inbred lines. Genetics. 175: 1267-74. PMID 17151250 DOI: 10.1534/Genetics.106.064063  0.352
2007 Nichols KM, Broman KW, Sundin K, Young JM, Wheeler PA, Thorgaard GH. Quantitative trait loci x maternal cytoplasmic environment interaction for development rate in Oncorhynchus mykiss. Genetics. 175: 335-47. PMID 17057232 DOI: 10.1534/Genetics.106.064311  0.41
2006 Broman KW, Sen S, Owens SE, Manichaikul A, Southard-Smith EM, Churchill GA. The X chromosome in quantitative trait locus mapping. Genetics. 174: 2151-8. PMID 17028340 DOI: 10.1534/Genetics.106.061176  0.612
2006 Kess D, Lindqvist AK, Peters T, Wang H, Zamek J, Nischt R, Broman KW, Blakytny R, Krieg T, Holmdahl R, Scharffetter-Kochanek K. Identification of susceptibility loci for skin disease in a murine psoriasis model. Journal of Immunology (Baltimore, Md. : 1950). 177: 4612-9. PMID 16982899 DOI: 10.4049/Jimmunol.177.7.4612  0.378
2006 Sundin OH, Broman KW, Chang HH, Vito EC, Stark WJ, Gottsch JD. A common locus for late-onset Fuchs corneal dystrophy maps to 18q21.2-q21.32. Investigative Ophthalmology & Visual Science. 47: 3919-26. PMID 16936105 DOI: 10.1167/Iovs.05-1619  0.393
2006 Grant GR, Robinson SW, Edwards RE, Clothier B, Davies R, Judah DJ, Broman KW, Smith AG. Multiple polymorphic loci determine basal hepatic and splenic iron status in mice. Hepatology (Baltimore, Md.). 44: 174-85. PMID 16799992 DOI: 10.1002/Hep.21233  0.383
2006 Manichaikul A, Dupuis J, Sen S, Broman KW. Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus. Genetics. 174: 481-9. PMID 16783000 DOI: 10.1534/Genetics.106.061549  0.637
2006 Feenstra B, Skovgaard IM, Broman KW. Mapping quantitative trait loci by an extension of the Haley-Knott regression method using estimating equations. Genetics. 173: 2269-82. PMID 16702423 DOI: 10.1534/Genetics.106.058537  0.378
2006 Chadwick LH, Pertz LM, Broman KW, Bartolomei MS, Willard HF. Genetic control of X chromosome inactivation in mice: Definition of the Xce candidate interval Genetics. 173: 2103-2110. PMID 16582439 DOI: 10.1534/Genetics.105.054882  0.445
2006 Orgogozo V, Broman KW, Stern DL. High-resolution quantitative trait locus mapping reveals sign epistasis controlling ovariole number between two Drosophila species. Genetics. 173: 197-205. PMID 16489225 DOI: 10.1534/Genetics.105.054098  0.503
2006 Shrestha S, Strathdee SA, Broman KW, Smith MW. Unknown biological mixtures evaluation using STR analytical quantification. Electrophoresis. 27: 409-15. PMID 16437418 DOI: 10.1002/Elps.200500502  0.339
2006 Reilly KM, Broman KW, Bronson RT, Tsang S, Loisel DA, Christy ES, Sun Z, Diehl J, Munroe DJ, Tuskan RG. An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model. Cancer Research. 66: 62-8. PMID 16397217 DOI: 10.1158/0008-5472.Can-05-1480  0.365
2006 Sundin OH, Jun AS, Broman KW, Liu SH, Sheehan SE, Vito EC, Stark WJ, Gottsch JD. Linkage of late-onset Fuchs corneal dystrophy to a novel locus at 13pTel-13q12.13. Investigative Ophthalmology & Visual Science. 47: 140-5. PMID 16384955 DOI: 10.1167/Iovs.05-0578  0.356
2005 Gottsch JD, Sundin OH, Liu SH, Jun AS, Broman KW, Stark WJ, Vito EC, Narang AK, Thompson JM, Magovern M. Inheritance of a novel COL8A2 mutation defines a distinct early-onset subtype of fuchs corneal dystrophy. Investigative Ophthalmology & Visual Science. 46: 1934-9. PMID 15914606 DOI: 10.1167/Iovs.04-0937  0.347
2005 Owens SE, Broman KW, Wiltshire T, Elmore JB, Bradley KM, Smith JR, Southard-Smith EM. Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease. Human Molecular Genetics. 14: 1549-58. PMID 15843399 DOI: 10.1093/Hmg/Ddi163  0.469
2005 Broman KW. Mapping expression in randomized rodent genomes. Nature Genetics. 37: 209-10. PMID 15731750 DOI: 10.1038/Ng0305-209  0.393
2005 Guler ML, Ligons DL, Wang Y, Bianco M, Broman KW, Rose NR. Two autoimmune diabetes loci influencing T cell apoptosis control susceptibility to experimental autoimmune myocarditis. Journal of Immunology (Baltimore, Md. : 1950). 174: 2167-73. PMID 15699148 DOI: 10.4049/Jimmunol.174.4.2167  0.371
2005 Broman KW. The genomes of recombinant inbred lines. Genetics. 169: 1133-46. PMID 15545647 DOI: 10.1534/Genetics.104.035212  0.466
2005 Chen WM, Broman KW, Liang KY. Power and robustness of linkage tests for quantitative traits in general pedigrees. Genetic Epidemiology. 28: 11-23. PMID 15493059 DOI: 10.1002/Gepi.20034  0.388
2004 Chen S, Wang W, Broman KW, Katki HA, Parmigiani G. BayesMendel: an R environment for Mendelian risk prediction. Statistical Applications in Genetics and Molecular Biology. 3: Article21. PMID 16646800 DOI: 10.2202/1544-6115.1063  0.338
2004 Broman KW, Feingold E. SNPs made routine. Nature Methods. 1: 104-5. PMID 15782170 DOI: 10.1038/Nmeth1104-104  0.327
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/Ng1104-1133  0.382
2004 Sieberts SK, Broman KW, Gudbjartsson DF. "Bias toward the null" means reduced power. American Journal of Human Genetics. 75: 720-2; author reply . PMID 15338459 DOI: 10.1086/424756  0.43
2004 Neff MW, Robertson KR, Wong AK, Safra N, Broman KW, Slatkin M, Mealey KL, Pedersen NC. Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage. Proceedings of the National Academy of Sciences of the United States of America. 101: 11725-30. PMID 15289602 DOI: 10.1073/Pnas.0402374101  0.379
2004 Chen WM, Broman KW, Liang KY. Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression. Genetic Epidemiology. 26: 265-72. PMID 15095386 DOI: 10.1002/Gepi.10315  0.358
2004 Sivagnanasundaram S, Broman KW, Liu M, Petronis A. Quasi-linkage: a confounding factor in linkage analysis of complex diseases? Human Genetics. 114: 588-93. PMID 15045582 DOI: 10.1007/S00439-004-1109-7  0.433
2004 Tankersley CG, Broman KW. Interactions in hypoxic and hypercapnic breathing are genetically linked to mouse chromosomes 1 and 5. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 77-84. PMID 14978007 DOI: 10.1152/Japplphysiol.01102.2003  0.384
2003 Lidman O, Swanberg M, Horvath L, Broman KW, Olsson T, Piehl F. Discrete gene loci regulate neurodegeneration, lymphocyte infiltration, and major histocompatibility complex class II expression in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9817-23. PMID 14586010 DOI: 10.1523/Jneurosci.23-30-09817.2003  0.378
2003 Denny P, Hopes E, Gingles N, Broman KW, McPheat W, Morten J, Alexander J, Andrew PW, Brown SD. A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 448-53. PMID 12925893 DOI: 10.1007/S00335-002-2261-9  0.353
2003 Lamichhane G, Zignol M, Blades NJ, Geiman DE, Dougherty A, Grosset J, Broman KW, Bishai WR. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 7213-8. PMID 12775759 DOI: 10.1073/Pnas.1231432100  0.337
2003 Broman KW, Wu H, Sen S, Churchill GA. R/qtl: QTL mapping in experimental crosses Bioinformatics. 19: 889-890. PMID 12724300 DOI: 10.1093/Bioinformatics/Btg112  0.447
2003 Broman KW. Mapping quantitative trait loci in the case of a spike in the phenotype distribution Genetics. 163: 1169-1175. PMID 12663553  0.31
2003 Becanovic K, Wallstrom E, Kornek B, Glaser A, Broman KW, Dahlman I, Olofsson P, Holmdahl R, Luthman H, Lassmann H, Olsson T. New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis Journal of Immunology. 170: 1062-1069. PMID 12517974 DOI: 10.4049/Jimmunol.170.2.1062  0.422
2002 Jun AS, Broman KW, Do DV, Akpek EK, Stark WJ, Gottsch JD. Endothelial dystrophy, iris hypoplasia, congenital cataract, and stromal thinning (EDICT) syndrome maps to chromosome 15q22.1-q25.3 American Journal of Ophthalmology. 134: 172-176. PMID 12140022 DOI: 10.1016/S0002-9394(02)01401-0  0.374
2002 Broman KW, Rowe LB, Churchill GA, Paigen K. Crossover interference in the mouse Genetics. 160: 1123-1131. PMID 11901128  0.311
2002 Broman KW, Speed TP. A model selection approach for the identification of quantitative trait loci in experimental crosses Journal of the Royal Statistical Society: Series B (Statistical Methodology). 64: 641-656. DOI: 10.1111/1467-9868.00354  0.426
2002 Broman KW. Erratum: Broman KW. 2001. Estimation of Allele Frequencies With Data on Sibships. Genet Epidemiol 20:307-15. Genetic Epidemiology. 23: 465-466. DOI: 10.1002/Gepi.10194  0.339
2001 Broman KW. Estimation of allele frequencies with data on sibships Genetic Epidemiology. 20: 307-315. PMID 11255240 DOI: 10.1002/Gepi.2  0.323
2001 Boyartchuk VL, Broman KW, Mosher RE, D'Orazio SEF, Starnbach MN, Dietrich WF. Multigenic control of Listeria monocytogenes susceptibility in mice Nature Genetics. 27: 259-260. PMID 11242105 DOI: 10.1038/85812  0.406
2001 Yu A, Zhao C, Fan Y, Jang W, Mungall AJ, Deloukas P, Olsen A, Doggett NA, Ghebranious N, Broman KW, Weber JL. Comparison of human genetic and sequence-based physical maps. Nature. 409: 951-3. PMID 11237020 DOI: 10.1038/35057185  0.44
2001 Giglio S, Broman KW, Matsumoto N, Calvari V, Gimelli G, Neumann T, Ohashi H, Voullaire L, Larizza D, Giorda R, Weber JL, Ledbetter DH, Zuffardi O. Olfactory receptor-gene clusters, genomic-inversion polymorphisms, and common chromosome rearrangements. American Journal of Human Genetics. 68: 874-83. PMID 11231899 DOI: 10.1086/319506  0.342
2001 Lichter-Konecki U, Broman KW, Blau EB, Konecki DS. Genetic and physical mapping of the locus for autosomal dominant renal Fanconi syndrome, on chromosome 15q15.3 American Journal of Human Genetics. 68: 264-268. PMID 11090339 DOI: 10.1086/316923  0.413
2001 Weber JL, Broman KW. Genotyping for human whole-genome scans: past, present, and future. Advances in Genetics. 42: 77-96. PMID 11037315 DOI: 10.1016/S0065-2660(01)42016-5  0.339
2000 Kissebah AH, Sonnenberg GE, Myklebust J, Goldstein M, Broman K, James RG, Marks JA, Krakower GR, Jacob HJ, Weber J, Martin L, Blangero J, Comuzzie AG. Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome Proceedings of the National Academy of Sciences of the United States of America. 97: 14478-14483. PMID 11121050 DOI: 10.1073/Pnas.97.26.14478  0.43
2000 Witte JS, Goddard KA, Conti DV, Elston RC, Lin J, Suarez BK, Broman KW, Burmester JK, Weber JL, Catalona WJ. Genomewide scan for prostate cancer-aggressiveness loci. American Journal of Human Genetics. 67: 92-9. PMID 10825281 DOI: 10.1086/302960  0.392
2000 Broman KW, Weber JL. Characterization of human crossover interference. American Journal of Human Genetics. 66: 1911-26. PMID 10801387 DOI: 10.1086/302923  0.384
2000 Suarez BK, Lin J, Burmester JK, Broman KW, Weber JL, Banerjee TK, Goddard KA, Witte JS, Elston RC, Catalona WJ. A genome screen of multiplex sibships with prostate cancer. American Journal of Human Genetics. 66: 933-44. PMID 10712208 DOI: 10.1086/302818  0.313
2000 Brown AS, Feingold E, Broman KW, Sherman SL. Genome-wide variation in recombination in female meiosis: a risk factor for non-disjunction of chromosome 21. Human Molecular Genetics. 9: 515-23. PMID 10699174 DOI: 10.1093/Hmg/9.4.515  0.394
2000 Lichter-Konecki U, Broman KW, Dart R, Blau E, Konecki DS. The locus for autosomal dominant renal Fanconi Syndrome maps to the long arm of chromosome 15 Genetics in Medicine. 2: 106-106. DOI: 10.1097/00125817-200001000-00200  0.336
1999 Broman KW. Cleaning genotype data Genetic Epidemiology. 17. PMID 10597416 DOI: 10.1002/Gepi.1370170714  0.352
1999 Broman KW, Weber JL. Long homozygous chromosomal segments in reference families from the centre d'Etude du polymorphisme humain. American Journal of Human Genetics. 65: 1493-500. PMID 10577902 DOI: 10.1086/302661  0.308
1999 Broman KW, Weber JL. Method for constructing confidently ordered linkage maps. Genetic Epidemiology. 16: 337-43. PMID 10207715 DOI: 10.1002/(Sici)1098-2272(1999)16:4<337::Aid-Gepi1>3.0.Co;2-T  0.459
1999 Neff MW, Broman KW, Mellersh CS, Ray K, Acland GM, Aguirre GD, Ziegle JS, Ostrander EA, Rine J. A second-generation genetic linkage map of the domestic dog, Canis familiaris Genetics. 151: 803-820. PMID 9927471  0.382
1998 Broman KW, Weber JL. Estimation of pairwise relationships in the presence of genotyping errors. American Journal of Human Genetics. 63: 1563-4. PMID 9792888 DOI: 10.1086/302112  0.405
1998 Broman KW, Murray JC, Sheffield VC, White RL, Weber JL. Comprehensive human genetic maps: individual and sex-specific variation in recombination. American Journal of Human Genetics. 63: 861-9. PMID 9718341 DOI: 10.1086/302011  0.486
1996 Dernburg AF, Broman KW, Fung JC, Marshall WF, Philips J, Agard DA, Sedat JW. Perturbation of nuclear architecture by long-distance chromosome interactions. Cell. 85: 745-59. PMID 8646782 DOI: 10.1016/S0092-8674(00)81240-4  0.347
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