| Year |
Citation |
Score |
| 2024 |
Poscablo DM, Worthington AK, Smith-Berdan S, Rommel MGE, Manso BA, Adili R, Mok L, Reggiardo RE, Cool T, Mogharrab R, Myers J, Dahmen S, Medina P, Beaudin AE, Boyer SW, ... Holinstat M, et al. An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. Cell. PMID 38749423 DOI: 10.1016/j.cell.2024.04.018 |
0.359 |
|
| 2023 |
Stanger L, Yamaguchi A, Holinstat M. Antiplatelet strategies: past, present, and future. Journal of Thrombosis and Haemostasis : Jth. 21: 3317-3328. PMID 38000851 DOI: 10.1016/j.jtha.2023.09.013 |
0.393 |
|
| 2023 |
Kulkarni PP, Alluri RK, Godwin M, Forbes GL, Merkulova A, Vijay A, Palihati M, Kundu S, Jun-Shim Y, Schmaier A, Holinstat M, Cameron SJ, McCrae KR. Protection of β2GPI Deficient Mice from Thrombosis Reflects a Defect in PAR3-facilitated Platelet Activation. Biorxiv : the Preprint Server For Biology. PMID 37662286 DOI: 10.1101/2023.08.23.554547 |
0.308 |
|
| 2023 |
Larsen HJ, Byrne D, Özpolat T, Chauhan A, Bailey SL, Rhoads N, Reed F, Stolla MC, Adili R, Holinstat M, Fu X, Stolla M. Loss of 12-Lipoxygenase Improves the Post-Transfusion Function of Stored Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 37650322 DOI: 10.1161/ATVBAHA.123.319021 |
0.41 |
|
| 2023 |
Stanger L, Yamaguchi A, Yalavarthi P, Lambert S, Gilmore D, Rickenberg A, Luke C, Kumar K, Obi AT, White A, Bergh N, Dahlof BL, Holinstat M. The oxylipin analogue CS585 prevents platelet activation and thrombosis through activation of the prostacyclin receptor. Blood. PMID 37624927 DOI: 10.1182/blood.2023020622 |
0.489 |
|
| 2023 |
Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal D, Glukhova A. Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors. Blood. PMID 37506345 DOI: 10.1182/blood.2023020441 |
0.325 |
|
| 2023 |
Renna SA, Zhao X, Kunapuli SP, Ma P, Holinstat M, Boxer MB, Maloney DJ, Michael JV, McKenzie SE. Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 37345522 DOI: 10.1161/ATVBAHA.123.319434 |
0.309 |
|
| 2023 |
Banka AL, Guevara MV, Brannon ER, Nguyen NQ, Song S, Cady G, Pinsky DJ, Uhrich KE, Adili R, Holinstat M, Eniola-Adefeso O. Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nature Communications. 14: 2462. PMID 37117163 DOI: 10.1038/s41467-023-37990-z |
0.432 |
|
| 2023 |
Stanger L, Holinstat M. Bioactive lipid regulation of platelet function, hemostasis, and thrombosis. Pharmacology & Therapeutics. 246: 108420. PMID 37100208 DOI: 10.1016/j.pharmthera.2023.108420 |
0.441 |
|
| 2023 |
Yamaguchi A, van Hoorebeke C, Tourdot BE, Perry SC, Lee G, Rhoads N, Rickenberg A, Green AR, Sorrentino J, Yeung J, Freedman JC, Holman TR, Holinstat M. Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids. Pharmacology Research & Perspectives. 11: e01056. PMID 36708179 DOI: 10.1002/prp2.1056 |
0.524 |
|
| 2022 |
Holinstat M. Trauma is an exhausting platelet experience. Journal of Thrombosis and Haemostasis : Jth. 20: 1986-1987. PMID 35968791 DOI: 10.1111/jth.15825 |
0.327 |
|
| 2022 |
Yamaguchi A, Stanger L, Freedman JC, Prieur A, Thav R, Tena J, Holman TR, Holinstat M. Supplementation with omega-3 or omega-6 fatty acids attenuates platelet reactivity in postmenopausal women. Clinical and Translational Science. PMID 35791734 DOI: 10.1111/cts.13366 |
0.342 |
|
| 2021 |
Holinstat M. Controlling the Clot: ANXA7 Regulates Collagen Activation of Platelet Through 12-LOX. Circulation Research. 129: 508-510. PMID 34351797 DOI: 10.1161/CIRCRESAHA.121.319736 |
0.435 |
|
| 2021 |
Duan X, Perveen R, Dandamudi A, Adili R, Johnson J, Funk K, Berryman M, Davis AK, Holinstat M, Zheng Y, Akbar H. Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis. Scientific Reports. 11: 13170. PMID 34162972 DOI: 10.1038/s41598-021-92654-6 |
0.501 |
|
| 2021 |
Adili R, Jackson M, Stanger L, Dai X, Li M, Li BX, Holinstat M. Slounase, a Batroxobin Containing Activated Factor X Effectively Enhances Hemostatic Clot Formation and Reducing Bleeding in Hypocoagulant Conditions in Mice. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 27: 10760296211018510. PMID 34047195 DOI: 10.1177/10760296211018510 |
0.339 |
|
| 2021 |
Zaslavsky A, Adams M, Cao X, Yamaguchi A, Henderson J, Busch-Østergren P, Udager A, Pitchiaya S, Tourdot B, Kasputis T, Church SJ, Lee SK, Ohl S, Patel S, Morgan TM, ... ... Holinstat M, et al. Antisense oligonucleotides and nucleic acids generate hypersensitive platelets. Thrombosis Research. 200: 64-71. PMID 33540294 DOI: 10.1016/j.thromres.2021.01.006 |
0.34 |
|
| 2020 |
Yamaguchi A, Stanger L, Freedman CJ, Standley M, Hoang T, Adili R, Tsai WC, van Hoorebeke C, Holman TR, Holinstat M. DHA 12-LOX-derived oxylipins regulate platelet activation and thrombus formation through a PKA-dependent signaling pathway. Journal of Thrombosis and Haemostasis : Jth. PMID 33222370 DOI: 10.1111/jth.15184 |
0.401 |
|
| 2020 |
Yeung J, Adili R, Stringham EN, Luo R, Vizurraga A, Rosselli-Murai LK, Stoveken HM, Yu M, Piao X, Holinstat M, Tall GG. GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force. Proceedings of the National Academy of Sciences of the United States of America. PMID 33097663 DOI: 10.1073/pnas.2008921117 |
0.442 |
|
| 2020 |
Yeung J, Adili R, Yamaguchi A, Freedman CJ, Chen A, Shami R, Das A, Holman TR, Holinstat M. Omega-6 DPA and its 12-lipoxygenase-oxidized lipids regulate platelet reactivity in a nongenomic PPARα-dependent manner. Blood Advances. 4: 4522-4537. PMID 32946570 DOI: 10.1182/Bloodadvances.2020002493 |
0.669 |
|
| 2020 |
Freedman CJ, Tran A, Tourdot BE, Kalyanaraman C, Perry S, Holinstat M, Jacobson MP, Holman TR. Biosynthesis of the Maresin Intermediate, 13S,14S-epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and its Regulation through Negative Allosteric Modulators. Biochemistry. PMID 32324389 DOI: 10.1021/Acs.Biochem.0C00233 |
0.301 |
|
| 2019 |
Holinstat M. Resolvin the clot: DVT resolution through RvD4. Blood. 134: 1370-1371. DOI: 10.1182/Blood.2019002419 |
0.342 |
|
| 2018 |
Rost MS, Shestopalov I, Liu Y, Vo AH, Richter CE, Emly SM, Barrett FG, Stachura DL, Holinstat M, Zon LI, Shavit JA. Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish. Blood Advances. 2: 3418-3427. PMID 30504234 DOI: 10.1182/Blood.V128.22.2534.2534 |
0.393 |
|
| 2018 |
Green AR, Freedman CJ, Tena J, Tourdot BE, Liu B, Holinstat M, Holman TR. 5S,15S-Dihydroperoxyeicosatetraenoic acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1. Biochemistry. PMID 30407793 DOI: 10.1021/Acs.Biochem.8B00889 |
0.437 |
|
| 2018 |
Whitley MJ, Henke DM, Ghazi A, Nieman M, Stoller M, Simon LM, Chen E, Vesci J, Holinstat M, McKenzie SE, Shaw CA, Edelstein LC, Bray PF. The Protease-Activated Receptor 4 Ala120Thr Variant Alters Platelet Responsiveness to Low-Dose Thrombin, Protease-Activated Receptor 4 Desensitization and Is Blocked by Noncompetitive P2Y Inhibition. Journal of Thrombosis and Haemostasis : Jth. PMID 30347494 DOI: 10.1111/Jth.14318 |
0.475 |
|
| 2018 |
Adili R, Hawley M, Holinstat M. Regulation of platelet function and thrombosis by omega-3 and omega-6 polyunsaturated fatty acids. Prostaglandins & Other Lipid Mediators. 139: 10-18. PMID 30266534 DOI: 10.1016/J.Prostaglandins.2018.09.005 |
0.518 |
|
| 2018 |
Yeung J, Li W, Holinstat M. Platelet Signaling and Disease: Targeted Therapy for Thrombosis and Other Related Diseases. Pharmacological Reviews. 70: 526-548. PMID 29925522 DOI: 10.1124/Pr.117.014530 |
0.575 |
|
| 2018 |
Janapati S, Wurtzel J, Dangelmaier C, Manne BK, Bhavanasi D, Kostyak JC, Kim S, Holinstat M, Kunapuli SP, Goldfinger LE. TC21/RRas2 regulates GPVI-FcRγ-mediated platelet activation and thrombus stability. Journal of Thrombosis and Haemostasis : Jth. PMID 29883056 DOI: 10.1111/Jth.14197 |
0.546 |
|
| 2018 |
Tourdot BE, Stoveken H, Trumbo D, Yeung J, Kanthi Y, Edelstein LC, Bray PF, Tall GG, Holinstat M. Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29748334 DOI: 10.1161/Atvbaha.118.311112 |
0.489 |
|
| 2018 |
Holinstat M. New LINE(s) of Evidence for Genetic Regulation of Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 690-691. PMID 29563112 DOI: 10.1161/Atvbaha.118.310690 |
0.541 |
|
| 2018 |
Whitley M, Henke D, Simon L, Vesci J, Holinstat M, Nieman M, Shaw C, Bray P, Edelstein L. Abstract 015: PAR4 Ala120Thr Variant Alters PAR4 Desensitization, Sensitivity to Platelet Antagonists and Risk of Large Vessel Stroke Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.015 |
0.376 |
|
| 2017 |
Tourdot BE, Adili R, Isingizwe ZR, Ebrahem M, Freedman JC, Holman TR, Holinstat M. 12-HETrE inhibits platelet reactivity and thrombosis in part through the prostacyclin receptor. Blood Advances. 1: 1124-1131. PMID 29296755 DOI: 10.1182/Bloodadvances.2017006155 |
0.583 |
|
| 2017 |
Adili R, Voigt EM, Bormann JL, Foss KN, Hurley LJ, Meyer ES, Veldman AJ, Mast KA, West JL, Whiteheart SW, Holinstat M, Larson MK. In vivo modeling of docosahexaenoic acid and eicosapentaenoic acid-mediated inhibition of both platelet function and accumulation in arterial thrombi. Platelets. 1-9. PMID 29286871 DOI: 10.1080/09537104.2017.1420154 |
0.484 |
|
| 2017 |
Tourdot BE, Holinstat M. Targeting 12-Lipoxygenase as a Potential Novel Antiplatelet Therapy. Trends in Pharmacological Sciences. 38: 1006-1015. PMID 28863985 DOI: 10.1016/J.Tips.2017.08.001 |
0.437 |
|
| 2017 |
Adili R, Tourdot BE, Mast K, Yeung J, Freedman JC, Green A, Luci DK, Jadhav A, Simeonov A, Maloney DJ, Holman TR, Holinstat M. First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28775075 DOI: 10.1161/Atvbaha.117.309868 |
0.548 |
|
| 2017 |
McDougle DR, Watson JE, Abdeen AA, Adili R, Caputo MP, Krapf JE, Johnson RW, Kilian KA, Holinstat M, Das A. Anti-inflammatory ω-3 endocannabinoid epoxides. Proceedings of the National Academy of Sciences of the United States of America. PMID 28687674 DOI: 10.1073/Pnas.1610325114 |
0.574 |
|
| 2017 |
Holinstat M. Normal platelet function. Cancer and Metastasis Reviews. 36: 195-198. PMID 28667366 DOI: 10.1007/S10555-017-9677-X |
0.533 |
|
| 2017 |
Yeung J, Hawley M, Holinstat M. The expansive role of oxylipins on platelet biology. Journal of Molecular Medicine (Berlin, Germany). PMID 28528513 DOI: 10.1007/S00109-017-1542-4 |
0.53 |
|
| 2017 |
Kong X, Simon LM, Holinstat M, Shaw CA, Bray PF, Edelstein LC. Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP. Thrombosis and Haemostasis. PMID 28251237 DOI: 10.1160/Th16-09-0692 |
0.394 |
|
| 2016 |
Roy J, Adili R, Kulmacz RJ, Holinstat M, Das A. Development of Poly Unsaturated Fatty Acid Derivatives of Aspirin for Inhibition of Platelet Function. The Journal of Pharmacology and Experimental Therapeutics. PMID 27488919 DOI: 10.1124/Jpet.116.234781 |
0.629 |
|
| 2016 |
Yeung J, Tourdot BE, Adili R, Green AR, Freedman CJ, Fernandez-Perez P, Yu J, Holman TR, Holinstat M. 12-HETrE, a 12-Lipoxygenase Oxylipin of Dihomo-γ-Linolenic Acid, Inhibits Thrombosis via Gαs Signaling in Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27470510 DOI: 10.1161/Atvbaha.116.308050 |
0.384 |
|
| 2016 |
Tourdot B, Isingizwe Z, Yeung J, Adili R, Holinstat M. Potent Anti-Platelet Metabolite, 12-HETrE, Inhibits Platelet Activation and Thrombosis In Vivo Via Activation of the IP Receptor Blood. 128: 714-714. DOI: 10.1182/Blood.V128.22.714.714 |
0.579 |
|
| 2016 |
Whitley MJ, Vesci J, Holinstat M, Edelstein LC, Bray PF. The Common PAR4 Ala120Thr Variant Has a Major Effect on Platelet Reactivity to Thrombin and These Effects Are Enhanced with PAR1 and P2Y12 Inhibition Blood. 128: 709-709. DOI: 10.1182/Blood.V128.22.709.709 |
0.497 |
|
| 2015 |
Holinstat M, Bray PF. Protease receptor antagonism to target blood platelet therapies. Clinical Pharmacology and Therapeutics. 99: 72-81. PMID 26501993 DOI: 10.1002/Cpt.282 |
0.521 |
|
| 2015 |
Holinstat M, Tourdot BE. Coronary Heart Disease Risk Factors Take a Disproportional Toll on Women Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 750-751. PMID 25810295 DOI: 10.1161/Atvbaha.115.305466 |
0.423 |
|
| 2015 |
Kong X, Simon L, Leung K, Holinstat M, Shaw C, Bray PF, Edelstein LC. Identification of the Genetic Mechanism Responsible for Racially-Dimorphic Expression of the Thrombin-Receptor Regulator, Pctp Blood. 126: 415-415. DOI: 10.1182/Blood.V126.23.415.415 |
0.353 |
|
| 2015 |
Tourdot B, Bray PF, Edelstein LC, Holinstat M. Pharmacogenocis of PAR4: PAR4 Polymorphism Determines Platelet Response in the Presence of Dual Anti-Platelet Therapy Blood. 126: 3446-3446. DOI: 10.1182/Blood.V126.23.3446.3446 |
0.566 |
|
| 2015 |
Adili R, Holman TR, Holinstat M. Novel 12-LOX Inhibitor ML355 Attenuates Platelet Reactivity and Impairs Thrombus Growth, Stability and Vessel Occlusion In Vivo Blood. 126: 3442-3442. DOI: 10.1182/Blood.V126.23.3442.3442 |
0.553 |
|
| 2014 |
Edelstein LC, Simon LM, Lindsay CR, Kong X, Teruel-Montoya R, Tourdot BE, Chen ES, Ma L, Coughlin S, Nieman M, Holinstat M, Shaw CA, Bray PF. Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race. Blood. 124: 3450-8. PMID 25293779 DOI: 10.1182/Blood-2014-04-572479 |
0.542 |
|
| 2014 |
Tourdot BE, Conaway S, Niisuke K, Edelstein LC, Bray PF, Holinstat M. Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2644-50. PMID 25278289 DOI: 10.1161/Atvbaha.114.304249 |
0.52 |
|
| 2014 |
Yeung J, Tourdot BE, Fernandez-Perez P, Vesci J, Ren J, Smyrniotis CJ, Luci DK, Jadhav A, Simeonov A, Maloney DJ, Holman TR, McKenzie SE, Holinstat M. Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation. Blood. 124: 2271-9. PMID 25100742 DOI: 10.1182/Blood-2014-05-575878 |
0.604 |
|
| 2014 |
Cleator JH, Duvernay MT, Holinstat M, Colowick NE, Hudson WJ, Song Y, Harrell FE, Hamm HE. Racial differences in resistance to P2Y12receptor antagonists in type 2 diabetic subjects Journal of Pharmacology and Experimental Therapeutics. 351: 33-43. PMID 25052834 DOI: 10.1124/Jpet.114.215616 |
0.631 |
|
| 2014 |
Simon LM, Edelstein LC, Nagalla S, Woodley AB, Chen ES, Kong X, Ma L, Fortina P, Kunapuli S, Holinstat M, McKenzie SE, Dong JF, Shaw CA, Bray PF. Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics. Blood. 123: e37-45. PMID 24523238 DOI: 10.1182/Blood-2013-12-544692 |
0.339 |
|
| 2014 |
Luci DK, Jameson JB, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn N, Yeung J, Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, et al. Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. Journal of Medicinal Chemistry. 57: 495-506. PMID 24393039 DOI: 10.1021/Jm4016476 |
0.515 |
|
| 2014 |
Yeung J, Fernandez-Perez P, Vesci J, Holman TR, Ren J, Holinstat M. 12-HETrE, a Novel 12-LOX Oxylipin, Prevents Platelet Activation in a Gαs-like Manner Blood. 124: 1436-1436. DOI: 10.1182/Blood.V124.21.1436.1436 |
0.6 |
|
| 2014 |
Edelstein LC, Simon LM, Lindsay CR, Kong X, Montoya RT, Tourdot BE, Chen E, Ma L, Coughlin SR, Nieman MT, Holinstat M, Shaw C, Bray PF. Identification of a Racially Dimorphic Variant in the Human Platelet PAR4 Thrombin Receptor Altering Platelet Function and Pharmacologic Inhibition Blood. 124: 1434-1434. DOI: 10.1182/Blood.V124.21.1434.1434 |
0.554 |
|
| 2014 |
Yeung J, Apopa PL, Vesci J, Stolla M, Rai G, Simeonov A, Jadhav A, Fernandez-Perez P, Maloney DJ, Boutaud O, Holman TR, Holinstat M. Erratum to Yeung et al. "12- lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity" (Thromb Haemost 2013; 110: 569–581) Thrombosis and Haemostasis. 112: 426-426. DOI: 10.1160/Th14080001 |
0.4 |
|
| 2013 |
Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen ES, Bergeron A, Kong X, Nagalla S, Mohandas N, Cohen DE, Dong JF, Shaw C, Bray PF. Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nature Medicine. 19: 1609-16. PMID 24216752 DOI: 10.1038/Nm.3385 |
0.458 |
|
| 2013 |
Edelstein LC, McKenzie SE, Shaw C, Holinstat MA, Kunapuli SP, Bray PF. MicroRNAs in platelet production and activation. Journal of Thrombosis and Haemostasis : Jth. 11: 340-50. PMID 23809137 DOI: 10.1111/Jth.12214 |
0.326 |
|
| 2013 |
Yeung J, Apopa PL, Vesci J, Stolla M, Rai G, Simeonov A, Jadhav A, Fernandez-Perez P, Maloney DJ, Boutaud O, Holman TR, Holinstat M. 12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity Thrombosis and Haemostasis. 110: 569-581. PMID 23784669 DOI: 10.1160/Th13-01-0014 |
0.6 |
|
| 2013 |
Holinstat M, Colowick NE, Hudson WJ, Blakemore D, Chen Q, Hamm HE, Cleator JH. Dichotomous effects of exposure to bivalirudin in patients undergoing percutaneous coronary intervention on protease-activated receptor-mediated platelet activation Journal of Thrombosis and Thrombolysis. 35: 209-222. PMID 23054462 DOI: 10.1007/S11239-012-0812-9 |
0.689 |
|
| 2013 |
Simon LM, Edelstein LC, Nagalla S, Bergeron A, Chen E, Kong X, Ma L, Kunapuli SP, Holinstat M, McKenzie SE, Dong J, Shaw C, F Bray P. Effect Of Age and Gender On Human Platelet mRNA and Micro-RNA Levels Blood. 122: 3518-3518. DOI: 10.1182/Blood.V122.21.3518.3518 |
0.362 |
|
| 2013 |
Yeung J, Fernandez-Perez P, Vesci J, Mlt, Holman TR, Holinstat M. 12-Lipoxygenase Regulates Platelet Reactivity and Thrombosis Through Formation Of Unique Oxylipins Blood. 122: 3515-3515. DOI: 10.1182/Blood.V122.21.3515.3515 |
0.588 |
|
| 2013 |
Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen E, Woodley AB, Kong X, Nagalla S, Mohandas N, Cohen D, Dong J, Shaw CA, Bray PF. Racial Differences In Thrombin-Induced Human Platelet PAR4 Reactivity Blood. 122: 1054-1054. DOI: 10.1182/Blood.V122.21.1054.1054 |
0.502 |
|
| 2012 |
Ikei KN, Yeung J, Apopa PL, Ceja J, Vesci J, Holman TR, Holinstat M. Investigations of human platelet-type 12-lipoxygenase: Role of lipoxygenase products in platelet activation Journal of Lipid Research. 53: 2546-2559. PMID 22984144 DOI: 10.1194/Jlr.M026385 |
0.497 |
|
| 2012 |
Yeung J, Holinstat M. Newer agents in antiplatelet therapy: a review. Journal of Blood Medicine. 3: 33-42. PMID 22792011 DOI: 10.2147/Jbm.S25421 |
0.402 |
|
| 2012 |
Yeung J, Apopa PL, Vesci J, Kenyon V, Rai G, Jadhav A, Simeonov A, Holman TR, Maloney DJ, Boutaud O, Holinstat M. Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation Molecular Pharmacology. 81: 420-430. PMID 22155783 DOI: 10.1124/Mol.111.075630 |
0.611 |
|
| 2012 |
Pawlinski R, Holinstat M. We can do it together: PAR1/PAR2 heterodimer signaling in VSMCs. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2775-6. PMID 22096094 DOI: 10.1161/Atvbaha.111.238865 |
0.471 |
|
| 2012 |
Stefanini L, Boulaftali Y, Ouellette TD, Holinstat M, Désiré L, Leblond B, Andre P, Conley PB, Bergmeier W. Rap1-Rac1 circuits potentiate platelet activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 434-41. PMID 22075250 DOI: 10.1161/Atvbaha.111.239194 |
0.562 |
|
| 2012 |
Yeung J, Holinstat M. 12-lipoxygenase: a potential target for novel anti-platelet therapeutics. Cardiovascular & Hematological Agents in Medicinal Chemistry. 9: 154-64. PMID 21838667 DOI: 10.2174/187152511797037619 |
0.58 |
|
| 2012 |
Holinstat M. Oxygenase regulation of platelet-mediated hemostasis and thrombosis Journal of Molecular Biomarkers & Diagnosis. 1. DOI: 10.4172/2155-9929.S1.010 |
0.551 |
|
| 2012 |
Edelstein LC, Simon LM, Chen E, Bergeron A, Kong X, Ma L, Teruel-Montoya R, Holinstat M, Nagalla S, Dong J, Shaw C, Bray PF. A Large Cluster of Micrornas At 14q32 Defines an RNA Expression Module That Accounts for Racial Differences in Protease Activated Receptor 4-Mediated Platelet Reactivity Blood. 120: 380-380. DOI: 10.1182/Blood.V120.21.380.380 |
0.418 |
|
| 2012 |
Yeung J, Ikei K, Vesci J, Holman TR, Holinstat M. An ω-6 Fatty Acid, Dgla, Prevents Platelet Activation and Thrombosis in Vivo. Blood. 120: 2169-2169. DOI: 10.1182/Blood.V120.21.2169.2169 |
0.5 |
|
| 2011 |
Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, et al. Discovery of potent and selective inhibitors of human platelet-type 12-lipoxygenase Journal of Medicinal Chemistry. 54: 5485-5497. PMID 21739938 DOI: 10.1021/Jm2005089 |
0.359 |
|
| 2011 |
Holinstat M, Boutaud O, Apopa PL, Vesci J, Bala M, Oates JA, Hamm HE. Protease-activated receptor signaling in platelets activates cytosolic phospholipase a2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 435-442. PMID 21127289 DOI: 10.1161/Atvbaha.110.219527 |
0.668 |
|
| 2011 |
Yeung J, Ikei K, Vesci J, Arnouk A, Holman TR, Holinstat M. 12-HETrE, An Endogenous Inhibitor of Platelet Activation, Blood. 118: 3254-3254. DOI: 10.1182/Blood.V118.21.3254.3254 |
0.561 |
|
| 2011 |
Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Cα phosphorylates the TRPC1 channel and regulates store-operated Ca2+entry in endothelial cells. Journal of Biological Chemistry. 286: 36162-36162. DOI: 10.1074/Jbc.A111.313975 |
0.447 |
|
| 2010 |
Minshall RD, Vandenbroucke EE, Holinstat M, Place AT, Tiruppathi C, Vogel SM, van Nieuw Amerongen GP, Mehta D, Malik AB. Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvascular Research. 80: 240-9. PMID 20417648 DOI: 10.1016/J.Mvr.2010.04.007 |
0.545 |
|
| 2010 |
Apopa P, Patel M, Boutaud O, Holinstat M. Platelet 12-Lipoxygenase Is Required for Dense Granule Secretion and Platelet Aggregation: Role of 12-hLO In Platelet Hemostasis and Thrombosis Blood. 116: 3203-3203. DOI: 10.1182/Blood.V116.21.3203.3203 |
0.574 |
|
| 2009 |
Holinstat M, Preininger AM, Milne SB, Hudson WJ, Brown HA, Hamm HE. Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates Molecular Pharmacology. 76: 301-313. PMID 19483102 DOI: 10.1124/Mol.109.056622 |
0.718 |
|
| 2009 |
Holinstat M, Voss B, Bilodeau ML, Hamm HE. Erratum: Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway (Molecular Pharmacology (2007) 71 (686-694)) Molecular Pharmacology. 75: 730-731. DOI: 10.1124/Mol.75.3.730 |
0.682 |
|
| 2007 |
Voss B, McLaughlin JN, Holinstat M, Zent R, Hamm HE. PAR1, but not PAR4, activates human platelets through a G i/o/phosphoinositide-3 kinase signaling axis Molecular Pharmacology. 71: 1399-1406. PMID 17303701 DOI: 10.1124/Mol.106.033365 |
0.679 |
|
| 2007 |
Holinstat M, Voss B, Bilodeau ML, Hamm HE. Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway. Molecular Pharmacology. 71: 686-94. PMID 17151288 DOI: 10.1124/Mol.106.029371 |
0.729 |
|
| 2007 |
Holinstat M, Hudson WJ, Preininger AM, Hamm HE. Irreversible Platelet Activation Requires PAR1 Regulation of Phosphatidylinositol Phosphates (PIPns) Activation of Rap1. Blood. 110: 3889-3889. DOI: 10.1182/Blood.V110.11.3889.3889 |
0.715 |
|
| 2007 |
Holinstat M, Hudson WJ, Voss B, Hamm HE. PI‐3K differentially regulates protease activated receptor‐mediated platelet activation in humans through Rap1 The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A603-B |
0.669 |
|
| 2006 |
Holinstat M, Oldham WM, Hamm HE. G-protein-coupled receptors: Evolving views on physiological signalling: Symposium on G-Protein-Coupled Receptors: Evolving Concepts and New Techniques Embo Reports. 7: 866-869. PMID 16906127 DOI: 10.1038/Sj.Embor.7400788 |
0.544 |
|
| 2006 |
Holinstat M, Voss B, Bilodeau ML, McLaughlin JN, Cleator J, Hamm HE. PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation. The Journal of Biological Chemistry. 281: 26665-74. PMID 16837456 DOI: 10.1074/Jbc.M602174200 |
0.716 |
|
| 2006 |
Holinstat M, Knezevic N, Broman M, Samarel AM, Malik AB, Mehta D. Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability. The Journal of Biological Chemistry. 281: 2296-305. PMID 16308318 DOI: 10.1074/Jbc.M511248200 |
0.544 |
|
| 2006 |
Holinstat M, Hamm HE. Protease Activated Receptors Differentially Regulate Human Platelet Activation through Phosphatidic Acid-Dependent DAG Formation. Blood. 108: 3906-3906. DOI: 10.1182/Blood.V108.11.3906.3906 |
0.736 |
|
| 2005 |
McLaughlin JN, Shen L, Holinstat M, Brooks JD, DiBenedetto E, Hamm HE. Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1 Journal of Biological Chemistry. 280: 25048-25059. PMID 15878870 DOI: 10.1074/Jbc.M414090200 |
0.599 |
|
| 2004 |
Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. The Journal of Biological Chemistry. 279: 20941-9. PMID 15016832 DOI: 10.1074/Jbc.M313975200 |
0.504 |
|
| 2003 |
Mehta D, Ahmmed GU, Paria BC, Holinstat M, Voyno-Yasenetskaya T, Tiruppathi C, Minshall RD, Malik AB. RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. The Journal of Biological Chemistry. 278: 33492-500. PMID 12766172 DOI: 10.1074/Jbc.M302401200 |
0.52 |
|
| 2003 |
Holinstat M, Mehta D, Kozasa T, Minshall RD, Malik AB. Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement. The Journal of Biological Chemistry. 278: 28793-8. PMID 12754211 DOI: 10.1074/Jbc.M303900200 |
0.544 |
|
| 2002 |
Mehta D, Tiruppathi C, Sandoval R, Minshall RD, Holinstat M, Malik AB. Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. The Journal of Physiology. 539: 779-89. PMID 11897849 DOI: 10.1113/Jphysiol.2001.013289 |
0.526 |
|
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