Leonard I. Zon, M.D. - Publications

Affiliations: 
Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
Genetics, Chemical Engineering, Human Development
Website:
https://hsci.harvard.edu/people/leonard-i-zon-md

193 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Morad G, Carman CV, Hagedorn EJ, Perlin JR, Zon LI, Mustafaoglu N, Park TE, Ingber DE, Daisy CC, Moses MA. Tumor-Derived Extracellular Vesicles Breach the Intact Blood Brain Barrier via Transcytosis. Acs Nano. PMID 31479239 DOI: 10.1021/acsnano.9b04397  0.4
2019 Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. PMID 31435017 DOI: 10.1038/s41586-019-1489-4  1
2019 Cagan RL, Zon LI, White RM. Modeling Cancer with Flies and Fish. Developmental Cell. 49: 317-324. PMID 31063751 DOI: 10.1016/j.devcel.2019.04.013  0.6
2019 Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, ... ... Zon LI, et al. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science (New York, N.Y.). PMID 30705153 DOI: 10.1126/science.aav1749  0.68
2019 Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Aravena M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, et al. Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. PMID 30641053 DOI: 10.1053/j.gastro.2019.01.010  1
2018 Ablain J, Xu M, Rothschild H, Jordan RC, Mito JK, Daniels BH, Bell CF, Joseph NM, Wu H, Bastian BC, Zon LI, Yeh I. Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma. Science (New York, N.Y.). PMID 30385465 DOI: 10.1126/science.aau6509  0.44
2018 Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, et al. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. The Journal of Biological Chemistry. PMID 30366982 DOI: 10.1074/jbc.RA118.002742  1
2018 Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, ... ... Zon LI, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proceedings of the National Academy of Sciences of the United States of America. PMID 30139917 DOI: 10.1073/pnas.1806077115  1
2018 Mansour MR, He S, Li Z, Lobbardi R, Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, Blonquist T, Gjini E, Gutierrez A, Tang Q, Garcia-Perez L, ... ... Zon LI, et al. JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. The Journal of Experimental Medicine. PMID 29941549 DOI: 10.1084/jem.20170484  0.48
2018 Kapp FG, Perlin JR, Hagedorn EJ, Gansner JM, Schwarz DE, O'Connell LA, Johnson NS, Amemiya C, Fisher DE, Wölfle U, Trompouki E, Niemeyer CM, Driever W, Zon LI. Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. PMID 29899448 DOI: 10.1038/s41586-018-0213-0  1
2018 McConnell AM, Mito JK, Ablain J, Dang M, Formichella L, Fisher DE, Zon LI. Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion. Developmental Biology. PMID 29883661 DOI: 10.1016/j.ydbio.2018.05.026  0.44
2018 Bennett AH, O'Donohue MF, Gundry SR, Chan AT, Widrick J, Draper I, Chakraborty A, Zhou Y, Zon LI, Gleizes PE, Beggs AH, Gupta VA. RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes. Plos Genetics. 14: e1007226. PMID 29518074 DOI: 10.1371/journal.pgen.1007226  0.48
2018 Yu SH, Zhu KY, Zhang F, Wang J, Yuan H, Chen Y, Jin Y, Dong M, Wang L, Jia XE, Gao L, Dong ZW, Ren CG, Chen LT, Huang QH, ... ... Zon LI, et al. The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Biochimica Et Biophysica Acta. PMID 29378332 DOI: 10.1016/j.bbagrm.2017.12.009  0.48
2017 Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. Elife. 6. PMID 29117894 DOI: 10.7554/eLife.22626  0.4
2017 Neiswender JV, Kortum RL, Bourque C, Kasheta M, Zon L, Morrison DK, Ceol CJ. KIT suppresses BRAFV600E-mutant melanoma by attenuating oncogenic RAS/MAPK signaling. Cancer Research. PMID 28947418 DOI: 10.1158/0008-5472.CAN-17-0473  0.32
2017 Ciarlo C, Kaufman CK, Kinikoglu B, Michael J, Yang S, D Amato C, Blokzijl-Franke S, den Hertog J, Schlaeger TM, Zhou Y, Liao E, Zon LI. A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. Elife. 6. PMID 28832322 DOI: 10.7554/eLife.29145  0.48
2017 Choudhuri A, Fast EM, Zon LI. Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration. Stem Cell Reports. 8: 1465-1471. PMID 28591648 DOI: 10.1016/j.stemcr.2017.05.018  0.32
2017 Fazio M, Avagyan S, van Rooijen E, Mannherz W, Kaufman CK, Lobbardi R, Langenau DM, Zon LI. Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors. Zebrafish. PMID 28557653 DOI: 10.1089/zeb.2017.1434  0.48
2017 Theodore LN, Hagedorn EJ, Cortes M, Natsuhara K, Liu SY, Perlin JR, Yang S, Daily ML, Zon LI, North TE. Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization. Stem Cell Reports. PMID 28416284 DOI: 10.1016/j.stemcr.2017.03.016  1
2017 Hockman D, Burns A, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PD, Lickert H, et al. Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. Elife. 6. PMID 28387645 DOI: 10.7554/eLife.21231  0.4
2017 Blaser BW, Moore JL, Hagedorn EJ, Li B, Riquelme R, Lichtig A, Yang S, Zhou Y, Tamplin OJ, Binder V, Zon LI. CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of Experimental Medicine. PMID 28351983 DOI: 10.1084/jem.20161616  1
2017 Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, ... ... Zon LI, et al. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Science Translational Medicine. 9. PMID 28179501 DOI: 10.1126/scitranslmed.aah5645  1
2017 Gansner JM, Leung AD, Superdock M, Blair MC, Ammerman MB, Durand EM, Barut B, Handin RI, Stachura DL, Lu C, Springer TA, Zon LI. Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity. Blood. PMID 28126924 DOI: 10.1182/blood-2016-12-759993  0.44
2016 van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, ... ... Zon LI, et al. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American Journal of Human Genetics. PMID 28017375 DOI: 10.1016/j.ajhg.2016.11.016  1
2016 Rossmann MP, Zhou Y, Zon LI. Development: For cloche the Bell Tolls. Current Biology : Cb. 26: R890-R892. PMID 27728792 DOI: 10.1016/j.cub.2016.08.009  0.48
2016 Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, ... ... Zon LI, et al. Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes. Blood. PMID 27554085 DOI: 10.1182/blood-2016-02-697870  0.32
2016 Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI. Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. Journal of Visualized Experiments : Jove. PMID 27341538 DOI: 10.3791/54168  0.4
2016 Rowe RG, Mandelbaum J, Zon LI, Daley GQ. Engineering Hematopoietic Stem Cells: Lessons from Development. Cell Stem Cell. 18: 707-20. PMID 27257760 DOI: 10.1016/j.stem.2016.05.016  1
2016 Dang M, Fogley R, Zon LI. Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish. Advances in Experimental Medicine and Biology. 916: 103-24. PMID 27165351 DOI: 10.1007/978-3-319-30654-4_5  1
2016 Svoboda O, Stachura DL, Machonova O, Zon LI, Traver D, Bartunek P. Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nature Protocols. 11: 1007-20. PMID 27123951 DOI: 10.1038/nprot.2016.053  0.68
2016 Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... ... Zon LI, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/j.molcel.2016.03.013  1
2016 Avagyan S, Zon LI. FISH TO LEARN: INSIGHTS INTO BLOOD DEVELOPMENT AND BLOOD DISORDERS FROM ZEBRAFISH HEMATOPOIESIS. Human Gene Therapy. PMID 27018965 DOI: 10.1089/hum.2016.024  1
2016 Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, ... ... Zon LI, et al. A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science (New York, N.Y.). 351: aad2197. PMID 26823433 DOI: 10.1126/science.aad2197  1
2016 Huang J, Liu X, Li D, Shao Z, Cao H, Zhang Y, Trompouki E, Bowman TV, Zon LI, Yuan GC, Orkin SH, Xu J. Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. Developmental Cell. 36: 9-23. PMID 26766440 DOI: 10.1016/j.devcel.2015.12.014  1
2015 Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, ... ... Zon LI, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. PMID 26607381 DOI: 10.1016/j.stem.2015.09.015  0.36
2015 Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, ... ... Zon LI, et al. Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. Blood. PMID 26385351 DOI: 10.1182/blood-2015-07-659276  1
2015 Mosimann C, Panáková D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, ... Zon LI, et al. Chamber identity programs drive early functional partitioning of the heart. Nature Communications. 6: 8146. PMID 26306682 DOI: 10.1038/ncomms9146  1
2015 Heilmann S, Ratnakumar K, Langdon E, Kansler E, Kim I, Campbell NR, Perry E, McMahon A, Kaufman C, van Rooijen E, Lee W, Iacobuzio-Donahue C, Hynes R, Zon L, Xavier J, et al. A quantitative system for studying metastasis using transparent zebrafish. Cancer Research. PMID 26282170 DOI: 10.1158/0008-5472.CAN-14-3319  1
2015 Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 523: 468-71. PMID 26201599 DOI: 10.1038/nature14569  1
2015 Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, ... ... Zon LI, et al. Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Research. PMID 26138676 DOI: 10.1038/cr.2015.81  0.48
2015 Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Zhu W, Peng J, ... ... Zon LI, et al. TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. Plos Genetics. 11: e1005346. PMID 26131719 DOI: 10.1371/journal.pgen.1005346  0.48
2015 Liu X, Jia X, Yuan H, Ma K, Chen Y, Jin Y, Deng M, Pan W, Chen S, Chen Z, de The H, Zon LI, Zhou Y, Zhou J, Zhu J. DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. Journal of Hematology & Oncology. 8: 15. PMID 25886310 DOI: 10.1186/s13045-015-0115-7  1
2015 Kim PG, Nakano H, Das PP, Chen MJ, Rowe RG, Chou SS, Ross SJ, Sakamoto KM, Zon LI, Schlaeger TM, Orkin SH, Nakano A, Daley GQ. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. The Journal of Experimental Medicine. 212: 633-48. PMID 25870201 DOI: 10.1084/jem.20141514  1
2015 Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, ... ... Zon LI, et al. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. The Journal of Experimental Medicine. 212: 649-63. PMID 25870200 DOI: 10.1084/jem.20141528  1
2015 Dang M, Zon LI. Screening for melanoma resistance genes in vivo. Pigment Cell & Melanoma Research. 28: 375-6. PMID 25818368 DOI: 10.1111/pcmr.12368  1
2015 Ablain J, Durand EM, Yang S, Zhou Y, Zon LI. A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish. Developmental Cell. 32: 756-64. PMID 25752963 DOI: 10.1016/j.devcel.2015.01.032  0.48
2015 Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC, Orkin SH, ... ... Zon LI, et al. Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. Elife. 4. PMID 25714926 DOI: 10.7554/eLife.05544  1
2015 Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell. 160: 241-52. PMID 25594182 DOI: 10.1016/j.cell.2014.12.032  1
2015 Jang IH, Lu YF, Zhao L, Wenzel PL, Kume T, Datta SM, Arora N, Guiu J, Lagha M, Kim PG, Do EK, Kim JH, Schlaeger TM, Zon LI, Bigas A, et al. Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood. 125: 1418-26. PMID 25587036 DOI: 10.1182/blood-2014-04-568170  1
2015 Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, et al. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Molecular and Cellular Biology. 35: 789-804. PMID 25512612 DOI: 10.1128/MCB.00971-14  1
2015 Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, ... ... Zon LI, et al. A comparison of non-integrating reprogramming methods. Nature Biotechnology. 33: 58-63. PMID 25437882 DOI: 10.1038/nbt.3070  1
2014 Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic Acids Research. 42: 11777-91. PMID 25223788 DOI: 10.1093/nar/gku805  0.48
2014 Hagedorn EJ, Durand EM, Fast EM, Zon LI. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. Experimental Cell Research. 329: 220-6. PMID 25094063 DOI: 10.1016/j.yexcr.2014.07.030  1
2014 Guo C, Chen X, Song H, Maynard MA, Zhou Y, Lobanov AV, Gladyshev VN, Ganis JJ, Wiley D, Jugo RH, Lee NY, Castroneves LA, Zon LI, Scanlan TS, Feldman HA, et al. Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. Endocrinology. 155: 4069-80. PMID 25004091 DOI: 10.1210/en.2013-2029  0.6
2014 Svoboda O, Stachura DL, Machoňová O, Pajer P, Brynda J, Zon LI, Traver D, Bartůněk P. Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 124: 220-8. PMID 24869937 DOI: 10.1182/blood-2014-03-564682  1
2014 Kong Y, Grimaldi M, Curtin E, Dougherty M, Kaufman C, White RM, Zon LI, Liao EC. Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation. Chemistry & Biology. 21: 488-501. PMID 24684905 DOI: 10.1016/j.chembiol.2014.02.013  1
2014 Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry BJ, Mochida GH, Hill RS, Weimer JM, Stein Q, Poduri A, Partlow JN, Ville D, Dulac O, Yu TW, ... ... Zon LI, et al. Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. American Journal of Human Genetics. 94: 547-58. PMID 24656866 DOI: 10.1016/j.ajhg.2014.03.003  1
2014 Hagedorn EJ, Zon LI. Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones. The Journal of Experimental Medicine. 211: 384-5. PMID 24616474 DOI: 10.1084/jem.2113insight2  1
2013 Paik EJ, Mahony S, White RM, Price EN, Dibiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI. A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 1: 425-36. PMID 24286030 DOI: 10.1016/j.stemcr.2013.10.001  1
2013 Ablain J, Zon LI. Of fish and men: using zebrafish to fight human diseases. Trends in Cell Biology. 23: 584-6. PMID 24275383 DOI: 10.1016/j.tcb.2013.09.009  0.44
2013 Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature Cell Biology. 15: 1516-25. PMID 24240475 DOI: 10.1038/ncb2870  1
2013 Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell. 155: 909-21. PMID 24209627 DOI: 10.1016/j.cell.2013.10.023  1
2013 Chen CH, Durand E, Wang J, Zon LI, Poss KD. zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development (Cambridge, England). 140: 4988-97. PMID 24198277 DOI: 10.1242/dev.102053  1
2013 Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, ... ... Zon LI, et al. The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome Biology. 14: R113. PMID 24148783 DOI: 10.1186/gb-2013-14-10-r113  1
2013 Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D. The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 122: 3918-28. PMID 24128862 DOI: 10.1182/blood-2012-12-475392  1
2013 Doulatov S, Vo LT, Chou SS, Kim PG, Arora N, Li H, Hadland BK, Bernstein ID, Collins JJ, Zon LI, Daley GQ. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell. 13: 459-70. PMID 24094326 DOI: 10.1016/j.stem.2013.09.002  1
2013 Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, ... ... Zon LI, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/blood-2013-05-503177  1
2013 Boatman S, Barrett F, Satishchandran S, Jing L, Shestopalov I, Zon LI. Assaying hematopoiesis using zebrafish. Blood Cells, Molecules & Diseases. 51: 271-6. PMID 23916372 DOI: 10.1016/j.bcmd.2013.07.009  1
2013 Storer NY, White RM, Uong A, Price E, Nielsen GP, Langenau DM, Zon LI. Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. Development (Cambridge, England). 140: 3040-50. PMID 23821038 DOI: 10.1242/dev.087858  1
2013 Mosimann C, Puller AC, Lawson KL, Tschopp P, Amsterdam A, Zon LI. Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 949-63. PMID 23723152 DOI: 10.1002/dvdy.23989  1
2013 Albacker CE, Storer NY, Langdon EM, Dibiase A, Zhou Y, Langenau DM, Zon LI. The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish. Plos One. 8: e64969. PMID 23705022 DOI: 10.1371/journal.pone.0064969  1
2013 Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills AA, DiBiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, Zon LI. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development (Cambridge, England). 140: 2354-64. PMID 23615277 DOI: 10.1242/dev.088427  1
2013 Kim PG, Albacker CE, Lu YF, Jang IH, Lim Y, Heffner GC, Arora N, Bowman TV, Lin MI, Lensch MW, De Los Angeles A, Zon LI, Loewer S, Daley GQ. Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proceedings of the National Academy of Sciences of the United States of America. 110: E141-50. PMID 23236128 DOI: 10.1073/pnas.1214361110  1
2013 Jing CB, Chen Y, Dong M, Peng XL, Jia XE, Gao L, Ma K, Deng M, Liu TX, Zon LI, Zhu J, Zhou Y, Zhou Y. Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish. Developmental Biology. 374: 24-31. PMID 23220656 DOI: 10.1016/j.ydbio.2012.11.032  0.48
2013 Bai X, Trowbridge JJ, Riley E, Lee JA, DiBiase A, Kaartinen VM, Orkin SH, Zon LI. TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes. Developmental Biology. 373: 422-30. PMID 23159334 DOI: 10.1016/j.ydbio.2012.10.008  1
2013 Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, et al. Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Developmental Biology. 373: 431-41. PMID 22960038 DOI: 10.1016/j.ydbio.2012.08.015  1
2012 Tamplin OJ, White RM, Jing L, Kaufman CK, Lacadie SA, Li P, Taylor AM, Zon LI. Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 459-68. PMID 23801494 DOI: 10.1002/wdev.37  1
2012 McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon EM, Lengerke C, Zon LI, Collins JJ, Daley GQ. The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell. 11: 701-14. PMID 23122293 DOI: 10.1016/j.stem.2012.07.018  1
2012 Mochida GH, Ganesh VS, de Michelena MI, Dias H, Atabay KD, Kathrein KL, Huang HT, Hill RS, Felie JM, Rakiec D, Gleason D, Hill AD, Malik AN, Barry BJ, Partlow JN, ... ... Zon LI, et al. CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nature Genetics. 44: 1260-4. PMID 23023333 DOI: 10.1038/ng.2425  1
2012 Jing L, Durand EM, Ezzio C, Pagliuca SM, Zon LI. In situ hybridization assay-based small molecule screening in zebrafish. Current Protocols in Chemical Biology. 4. PMID 23001521 DOI: 10.1002/9780470559277.ch110236  0.44
2012 Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, ... ... Zon LI, et al. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell. 150: 1135-46. PMID 22980977 DOI: 10.1016/j.cell.2012.07.033  1
2012 Gupta VA, Kawahara G, Myers JA, Chen AT, Hall TE, Manzini MC, Currie PD, Zhou Y, Zon LI, Kunkel LM, Beggs AH. A splice site mutation in laminin-α2 results in a severe muscular dystrophy and growth abnormalities in zebrafish. Plos One. 7: e43794. PMID 22952766 DOI: 10.1371/journal.pone.0043794  1
2012 Sorrells S, Carbonneau S, Harrington E, Chen AT, Hast B, Milash B, Pyati U, Major MB, Zhou Y, Zon LI, Stewart RA, Look AT, Jette C. Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53. Plos Genetics. 8: e1002922. PMID 22952453 DOI: 10.1371/journal.pgen.1002922  1
2012 Oubaha M, Lin MI, Margaron Y, Filion D, Price EN, Zon LI, Côté JF, Gratton JP. Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. Blood. 120: 3371-81. PMID 22936663 DOI: 10.1182/blood-2012-03-419721  1
2012 de Jong JL, Zon LI. Histocompatibility and hematopoietic transplantation in the zebrafish. Advances in Hematology. 2012: 282318. PMID 22778744 DOI: 10.1155/2012/282318  0.48
2012 Ganis JJ, Hsia N, Trompouki E, de Jong JL, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, Zon LI. Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Developmental Biology. 366: 185-94. PMID 22537494 DOI: 10.1016/j.ydbio.2012.03.021  1
2012 Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI. Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental Cell. 22: 625-38. PMID 22421047 DOI: 10.1016/j.devcel.2012.01.003  1
2012 Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, ... Zon LI, et al. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Molecular Cell. 45: 330-43. PMID 22325351 DOI: 10.1016/j.molcel.2011.11.032  1
2012 Bowman TV, Trompouki E, Zon LI. Linking hematopoietic regeneration to developmental signaling pathways: a story of BMP and Wnt. Cell Cycle (Georgetown, Tex.). 11: 424-5. PMID 22262185 DOI: 10.4161/cc.11.3.19161  1
2012 Brown KH, Dobrinski KP, Lee AS, Gokcumen O, Mills RE, Shi X, Chong WW, Chen JY, Yoo P, David S, Peterson SM, Raj T, Choy KW, Stranger BE, Williamson RE, ... Zon LI, et al. Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis. Proceedings of the National Academy of Sciences of the United States of America. 109: 529-34. PMID 22203992 DOI: 10.1073/pnas.1112163109  1
2012 Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP. An optical platform for cell tracking in adult zebrafish. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 176-82. PMID 22162445 DOI: 10.1002/cyto.a.21167  1
2012 Taylor AM, Humphries JM, White RM, Murphey RD, Burns CE, Zon LI. Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Experimental Hematology. 40: 228-237.e5. PMID 22120640 DOI: 10.1016/j.exphem.2011.11.007  1
2011 Detrich HW, Westerfield M, Zon LI. The zebrafish. Preface. Methods in Cell Biology. 105: xxi-xxii. PMID 22043535  1
2011 Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu DC, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand EM, Mosimann C, Heffner GC, Daley GQ, ... ... Zon LI, et al. Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell. 147: 577-89. PMID 22036566 DOI: 10.1016/j.cell.2011.09.044  1
2011 Li P, White RM, Zon LI. Transplantation in zebrafish. Methods in Cell Biology. 105: 403-17. PMID 21951540 DOI: 10.1016/B978-0-12-381320-6.00017-5  1
2011 Bugeon L, Taylor HB, Progatzky F, Lin MI, Ellis CD, Welsh N, Smith E, Vargesson N, Gray C, Renshaw SA, Chico TJ, Zon LI, Lamb J, Dallman MJ. The NOTCH pathway contributes to cell fate decision in myelopoiesis. Haematologica. 96: 1753-60. PMID 21933862 DOI: 10.3324/haematol.2011.044115  1
2011 Trompouki E, Bowman TV, Dibiase A, Zhou Y, Zon LI. Chromatin immunoprecipitation in adult zebrafish red cells. Methods in Cell Biology. 104: 341-52. PMID 21924172 DOI: 10.1016/B978-0-12-374814-0.00019-7  1
2011 Zhou Y, Zon LI. The zon laboratory guide to positional cloning in zebrafish. Methods in Cell Biology. 104: 287-309. PMID 21924169 DOI: 10.1016/B978-0-12-374814-0.00016-1  0.48
2011 Mosimann C, Zon LI. Advanced zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments. Methods in Cell Biology. 104: 173-94. PMID 21924163 DOI: 10.1016/B978-0-12-374814-0.00010-0  0.4
2011 Bai X, Yang Z, Jiang H, Lin S, Zon LI. Genetic suppressor screens in haploids. Methods in Cell Biology. 104: 129-36. PMID 21924160 DOI: 10.1016/B978-0-12-374814-0.00007-0  1
2011 Jing L, Zon LI. Zebrafish as a model for normal and malignant hematopoiesis. Disease Models & Mechanisms. 4: 433-8. PMID 21708900 DOI: 10.1242/dmm.006791  0.36
2011 Li P, Zon LI. Stem cell migration: a zebrafish model. Methods in Molecular Biology (Clifton, N.J.). 750: 157-68. PMID 21618090 DOI: 10.1007/978-1-61779-145-1_11  1
2011 Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, et al. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 8: 445-58. PMID 21474107 DOI: 10.1016/j.stem.2011.02.003  1
2011 Taylor AM, Zon LI. Modeling Diamond Blackfan anemia in the zebrafish. Seminars in Hematology. 48: 81-8. PMID 21435504 DOI: 10.1053/j.seminhematol.2011.02.002  0.36
2011 White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, ... ... Zon LI, et al. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature. 471: 518-22. PMID 21430780 DOI: 10.1038/nature09882  1
2011 Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, ... ... Zon LI, et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 471: 513-7. PMID 21430779 DOI: 10.1038/nature09806  1
2011 Stachura DL, Svoboda O, Lau RP, Balla KM, Zon LI, Bartunek P, Traver D. Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood. 118: 1274-82. PMID 21415264 DOI: 10.1182/blood-2011-01-331199  1
2011 de Jong JL, Burns CE, Chen AT, Pugach E, Mayhall EA, Smith AC, Feldman HA, Zhou Y, Zon LI. Characterization of immune-matched hematopoietic transplantation in zebrafish. Blood. 117: 4234-42. PMID 21346254 DOI: 10.1182/blood-2010-09-307488  1
2011 Alexander MS, Kawahara G, Kho AT, Howell MH, Pusack TJ, Myers JA, Montanaro F, Zon LI, Guyon JR, Kunkel LM. Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors. Muscle & Nerve. 43: 741-50. PMID 21337346 DOI: 10.1002/mus.21972  1
2011 Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT. cpsf1 is required for definitive HSC survival in zebrafish. Blood. 117: 3996-4007. PMID 21330472 DOI: 10.1182/blood-2010-08-304030  1
2011 Lacadie SA, Zon LI. The ERGonomics of hematopoietic stem cell self-renewal. Genes & Development. 25: 289-93. PMID 21325129 DOI: 10.1101/gad.2031511  1
2011 Gupta V, Kawahara G, Gundry SR, Chen AT, Lencer WI, Zhou Y, Zon LI, Kunkel LM, Beggs AH. The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Human Molecular Genetics. 20: 1712-25. PMID 21296866 DOI: 10.1093/hmg/ddr047  1
2011 Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, Zon LI. Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (Cambridge, England). 138: 169-77. PMID 21138979 DOI: 10.1242/dev.059345  1
2010 Durand EM, Zon LI. Stem cells: The blood balance. Nature. 468: 644-5. PMID 21124447 DOI: 10.1038/468644a  0.44
2010 Detrich HW, Westerfield M, Zon LI. The zebrafish: cellular and developmental biology, part A. Preface. Methods in Cell Biology. 100: xiii. PMID 21111211 DOI: 10.1016/B978-0-12-384892-5.00018-9  1
2010 Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, et al. T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell. 18: 353-66. PMID 20951945 DOI: 10.1016/j.ccr.2010.09.009  1
2010 North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 17315-20. PMID 20855591 DOI: 10.1073/pnas.1008209107  1
2010 Paik EJ, Zon LI. Hematopoietic development in the zebrafish. The International Journal of Developmental Biology. 54: 1127-37. PMID 20711990 DOI: 10.1387/ijdb.093042ep  1
2010 Storer NY, Zon LI. Zebrafish models of p53 functions. Cold Spring Harbor Perspectives in Biology. 2: a001123. PMID 20679337 DOI: 10.1101/cshperspect.a001123  0.92
2010 Tamplin OJ, Zon LI. Fishing at the cellular level. Nature Methods. 7: 600-1. PMID 20676080 DOI: 10.1038/nmeth0810-600  0.84
2010 Tamplin OJ, Zon LI. Blood flow: metalloproteases cut loose in primitive erythrocytes. Current Biology : Cb. 20: R561-2. PMID 20619808 DOI: 10.1016/j.cub.2010.05.014  0.84
2010 Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, ... Zon LI, et al. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 142: 133-43. PMID 20603019 DOI: 10.1016/j.cell.2010.05.028  1
2010 Koo S, Huntly BJ, Wang Y, Chen J, Brumme K, Ball B, McKinney-Freeman SL, Yabuuchi A, Scholl C, Bansal D, Zon LI, Fröhling S, Daley GQ, Gilliland DG, Mercher T. Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis. Haematologica. 95: 1642-50. PMID 20494928 DOI: 10.3324/haematol.2010.023168  1
2010 Durand EM, Zon LI. Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment. Current Opinion in Hematology. 17: 308-12. PMID 20473159 DOI: 10.1097/MOH.0b013e32833a888c  0.44
2010 Paik EJ, de Jong JL, Pugach E, Opara P, Zon LI. A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. Zebrafish. 7: 61-8. PMID 20415644 DOI: 10.1089/zeb.2009.0643  1
2010 Zon LI, Peterson R. The new age of chemical screening in zebrafish. Zebrafish. 7: 1. PMID 20415642 DOI: 10.1089/zeb.2010.9996  1
2010 de Jong JL, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, Zon LI. Interaction of retinoic acid and scl controls primitive blood development. Blood. 116: 201-9. PMID 20410509 DOI: 10.1182/blood-2009-10-249557  1
2010 Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (New York, N.Y.). 327: 1650-3. PMID 20339075 DOI: 10.1126/science.1186624  1
2010 Li P, Zon LI. Resolving the controversy about N-cadherin and hematopoietic stem cells. Cell Stem Cell. 6: 199-202. PMID 20207222 DOI: 10.1016/j.stem.2010.02.007  1
2010 Smith AC, Raimondi AR, Salthouse CD, Ignatius MS, Blackburn JS, Mizgirev IV, Storer NY, de Jong JL, Chen AT, Zhou Y, Revskoy S, Zon LI, Langenau DM. High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood. 115: 3296-303. PMID 20056790 DOI: 10.1182/blood-2009-10-246488  0.92
2009 Dovey MC, Zon LI. Defining cancer stem cells by xenotransplantation in zebrafish. Methods in Molecular Biology (Clifton, N.J.). 568: 1-5. PMID 19582417 DOI: 10.1007/978-1-59745-280-9_1  0.48
2009 North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, Zon LI. Hematopoietic stem cell development is dependent on blood flow. Cell. 137: 736-48. PMID 19450519 DOI: 10.1016/j.cell.2009.04.023  1
2009 Burns CE, Galloway JL, Smith AC, Keefe MD, Cashman TJ, Paik EJ, Mayhall EA, Amsterdam AH, Zon LI. A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood. 113: 5776-82. PMID 19332767 DOI: 10.1182/blood-2008-12-193607  1
2009 Fraenkel PG, Gibert Y, Holzheimer JL, Lattanzi VJ, Burnett SF, Dooley KA, Wingert RA, Zon LI. Transferrin-a modulates hepcidin expression in zebrafish embryos. Blood. 113: 2843-50. PMID 19047682 DOI: 10.1182/blood-2008-06-165340  1
2008 Zon LI, Le X. Potential of zebrafish for anticancer drug screening. Expert Opinion On Drug Discovery. 3: 1451-60. PMID 23506108 DOI: 10.1517/17460440802580171  1
2008 Huang HT, Zon LI. Regulation of stem cells in the zebra fish hematopoietic system. Cold Spring Harbor Symposia On Quantitative Biology. 73: 111-8. PMID 19022765 DOI: 10.1101/sqb.2008.73.029  0.84
2008 Imamura S, Uchiyama J, Koshimizu E, Hanai J, Raftopoulou C, Murphey RD, Bayliss PE, Imai Y, Burns CE, Masutomi K, Gagos S, Zon LI, Roberts TM, Kishi S. A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. Plos One. 3: e3364. PMID 18846223 DOI: 10.1371/journal.pone.0003364  1
2008 Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI. montalcino, A zebrafish model for variegate porphyria. Experimental Hematology. 36: 1132-42. PMID 18550261 DOI: 10.1016/j.exphem.2008.04.008  1
2008 Langenau DM, Keefe MD, Storer NY, Jette CA, Smith AC, Ceol CJ, Bourque C, Look AT, Zon LI. Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish. Oncogene. 27: 4242-8. PMID 18345029 DOI: 10.1038/onc.2008.56  1
2008 Orkin SH, Zon LI. SnapShot: Hematopoiesis Cell. 132. PMID 18295585 DOI: 10.1016/j.cell.2008.02.013  1
2008 Orkin SH, Zon LI. Hematopoiesis: An Evolving Paradigm for Stem Cell Biology Cell. 132: 631-644. PMID 18295580 DOI: 10.1016/j.cell.2008.01.025  1
2008 Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Combinatorial regulation of novel erythroid gene expression in zebrafish. Experimental Hematology. 36: 424-32. PMID 18243489 DOI: 10.1016/j.exphem.2007.11.015  0.84
2007 North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 447: 1007-11. PMID 17581586 DOI: 10.1038/nature05883  1
2007 Pfaff KL, Straub CT, Chiang K, Bear DM, Zhou Y, Zon LI. The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization. Molecular and Cellular Biology. 27: 5887-97. PMID 17576815 DOI: 10.1128/MCB.00175-07  1
2007 Le X, Langenau DM, Keefe MD, Kutok JL, Neuberg DS, Zon LI. Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104: 9410-5. PMID 17517602 DOI: 10.1073/pnas.0611302104  1
2007 Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI. Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & Development. 21: 1382-95. PMID 17510286 DOI: 10.1101/gad.1545007  1
2007 Shepard JL, Amatruda JF, Finkelstein D, Ziai J, Finley KR, Stern HM, Chiang K, Hersey C, Barut B, Freeman JL, Lee C, Glickman JN, Kutok JL, Aster JC, Zon LI. A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes & Development. 21: 55-9. PMID 17210788 DOI: 10.1101/gad.1470407  1
2006 Murphey RD, Stern HM, Straub CT, Zon LI. A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chemical Biology & Drug Design. 68: 213-9. PMID 17105485 DOI: 10.1111/j.1747-0285.2006.00439.x  1
2006 Murphey RD, Zon LI. Small molecule screening in the zebrafish. Methods (San Diego, Calif.). 39: 255-61. PMID 16877005 DOI: 10.1016/j.ymeth.2005.09.019  0.88
2006 Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, ... ... Zon LI, et al. Mitoferrin is essential for erythroid iron assimilation. Nature. 440: 96-100. PMID 16511496 DOI: 10.1038/nature04512  1
2006 MacDonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, Kalluri R. Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood. 107: 1908-15. PMID 16254142 DOI: 10.1182/blood-2005-05-1814  1
2005 Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI. Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature Chemical Biology. 1: 366-70. PMID 16372403  1
2005 Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes & Development. 19: 2331-42. PMID 16166372 DOI: 10.1101/gad.1337005  1
2005 Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, ... ... Zon LI, et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 102: 13194-9. PMID 16150706 DOI: 10.1073/pnas.0506583102  1
2005 Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Schmidt B, Paw BH, Shaw GC, Kingsley P, Palis J, ... ... Zon LI, et al. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature. 436: 1035-39. PMID 16110529 DOI: 10.1038/nature03887  1
2005 Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, Andrews NC. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metabolism. 1: 191-200. PMID 16054062 DOI: 10.1016/j.cmet.2005.01.003  0.4
2005 Fraenkel PG, Traver D, Donovan A, Zahrieh D, Zon LI. Ferroportin1 is required for normal iron cycling in zebrafish Journal of Clinical Investigation. 115: 1532-1541. PMID 15902304 DOI: 10.1172/JCI23780  1
2005 Weber GJ, Choe SE, Dooley KA, Paffett-Lugassy NN, Zhou Y, Zon LI. Mutant-specific gene programs in the zebrafish. Blood. 106: 521-30. PMID 15827125 DOI: 10.1182/blood-2004-11-4541  1
2005 Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, ... Zon LI, et al. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Current Biology : Cb. 15: 249-54. PMID 15694309 DOI: 10.1016/j.cub.2005.01.031  0.88
2005 Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT. tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proceedings of the National Academy of Sciences of the United States of America. 102: 407-12. PMID 15630097 DOI: 10.1073/pnas.0406252102  1
2005 Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Developmental Cell. 8: 109-16. PMID 15621534 DOI: 10.1016/j.devcel.2004.12.001  0.84
2005 Paffett-Lugassy NN, Zon LI. Analysis of hematopoietic development in the zebrafish. Methods in Molecular Medicine. 105: 171-98. PMID 15492396  1
2004 Wingert RA, Brownlie A, Galloway JL, Dooley K, Fraenkel P, Axe JL, Davidson AJ, Barut B, Noriega L, Sheng X, Zhou Y, Zon LI. The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development (Cambridge, England). 131: 6225-35. PMID 15563524 DOI: 10.1242/dev.01540  1
2004 Ransom DG, Bahary N, Niss K, Traver D, Burns C, Trede NS, Paffett-Lugassy N, Saganic WJ, Lim CA, Hersey C, Zhou Y, Barut BA, Lin S, Kingsley PD, Palis J, ... ... Zon LI, et al. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. Plos Biology. 2: E237. PMID 15314655 DOI: 10.1371/journal.pbio.0020237  1
2003 Traver D, Herbomel P, Patton EE, Murphey RD, Yoder JA, Litman GW, Catic A, Amemiya CT, Zon LI, Trede NS. The zebrafish as a model organism to study development of the immune system. Advances in Immunology. 81: 253-330. PMID 14711058  1
2003 Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, ... ... Zon LI, et al. Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature Genetics. 34: 59-64. PMID 12669066 DOI: 10.1038/ng1137  1
2003 Galloway JL, Zon LI. Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Current Topics in Developmental Biology. 53: 139-58. PMID 12510667  0.84
2002 Donovan A, Brownlie A, Dorschner MO, Zhou Y, Pratt SJ, Paw BH, Phillips RB, Thisse C, Thisse B, Zon LI. The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood. 100: 4655-9. PMID 12393445 DOI: 10.1182/blood-2002-04-1169  1
2002 Murphey RD, Zon LI. Attack of the fish clones. Nature Biotechnology. 20: 785-6. PMID 12148002 DOI: 10.1038/nbt0802-785  0.88
2002 Amatruda JF, Shepard JL, Stern HM, Zon LI. Zebrafish as a cancer model system. Cancer Cell. 1: 229-31. PMID 12086858  1
2002 Orkin SH, Zon LI. Hematopoiesis and stem cells: Plasticity versus development heterogeneity Nature Immunology. 3: 323-328. PMID 11919568 DOI: 10.1038/ni0402-323  1
2001 Mead PE, Deconinck AE, Huber TL, Orkin SH, Zon LI. Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins. Development (Cambridge, England). 128: 2301-8. PMID 11493549  1
2000 Deconinck AE, Mead PE, Tevosian SG, Crispino JD, Katz SG, Zon LI, Orkin SH. FOG acts as a repressor of red blood cell development in Xenopus Development. 127: 2031-2040. PMID 10769228  1
2000 Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, ... ... Zon LI, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 403: 776-81. PMID 10693807 DOI: 10.1038/35001596  0.48
2000 Shepard JL, Zon LI. Developmental derivation of embryonic and adult macrophages. Current Opinion in Hematology. 7: 3-8. PMID 10608497  1
1999 Porcher C, Liao EC, Fujiwara Y, Zon LI, Orkin SH. Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding. Development (Cambridge, England). 126: 4603-15. PMID 10498694  1
1998 Brownlie A, Donovan A, Pratt SJ, Paw BH, Oates AC, Brugnara C, Witkowska HE, Sassa S, Zon LI. Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nature Genetics. 20: 244-50. PMID 9806542 DOI: 10.1038/3049  1
1998 Postlethwait JH, Yan YL, Gates MA, Horne S, Amores A, Brownlie A, Donovan A, Egan ES, Force A, Gong Z, Goutel C, Fritz A, Kelsh R, Knapik E, Liao E, ... ... Zon LI, et al. Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18: 345-9. PMID 9537416 DOI: 10.1038/ng0498-345  1
1997 Orkin SH, Zon LI. Genetics of erythropoiesis: Induced mutations in mice and zebrafish Annual Review of Genetics. 31: 33-60. PMID 9442889 DOI: 10.1146/annurev.genet.31.1.33  1
1997 Chan FY, Robinson J, Brownlie A, Shivdasani RA, Donovan A, Brugnara C, Kim J, Lau BC, Witkowska HE, Zon LI. Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 89: 688-700. PMID 9002973  0.4
1996 Kieran MW, Perkins AC, Orkin SH, Zon LI. Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. Proceedings of the National Academy of Sciences of the United States of America. 93: 9126-31. PMID 8799165  1
1993 Zon LI, Yamaguchi Y, Yee K, Albee EA, Kimura A, Bennett JC, Orkin SH, Ackerman SJ. Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. Blood. 81: 3234-41. PMID 8507862  1
1992 Sposi NM, Zon LI, Carè A, Valtieri M, Testa U, Gabbianelli M, Mariani G, Bottero L, Mather C, Orkin SH. Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors. Proceedings of the National Academy of Sciences of the United States of America. 89: 6353-7. PMID 1631130  1
1992 Zon LI, Orkin SH. Sequence of the human GATA-1 promoter Nucleic Acids Research. 20: 1812. PMID 1579480 DOI: 10.1093/nar/20.7.1812  1
1991 Zon LI, Mather C, Burgess S, Bolce ME, Harland RM, Orkin SH. Expression of GATA-binding proteins during embryonic development in Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America. 88: 10642-6. PMID 1961730  1
1991 Zon LI, Gurish MF, Stevens RL, Mather C, Reynolds DS, Austen KF, Orkin SH. GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene. The Journal of Biological Chemistry. 266: 22948-53. PMID 1744088  1
1991 Zon LI, Youssoufian H, Mather C, Lodish HF, Orkin SH. Activation of the erythropoietin receptor promoter by transcription factor GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 88: 10638-41. PMID 1660143  1
1990 Martin DI, Zon LI, Mutter G, Orkin SH. Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. Nature. 344: 444-7. PMID 2320112 DOI: 10.1038/344444a0  1
1990 Zon LI, Tsai SF, Burgess S, Matsudaira P, Bruns GAP, Orkin SH. The major human erythroid DNA-binding protein (GF-1): Primary sequence and localization of the gene to the X chromosome Proceedings of the National Academy of Sciences of the United States of America. 87: 668-672. PMID 2300555  1
1990 Youssoufian H, Zon LI, Orkin SH, D'Andrea AD, Lodish HF. Structure and transcription of the mouse erythropoietin receptor gene. Molecular and Cellular Biology. 10: 3675-82. PMID 2162479  1
1989 Tsai SF, Martin DI, Zon LI, D'Andrea AD, Wong GG, Orkin SH. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature. 339: 446-51. PMID 2725678 DOI: 10.1038/339446a0  1
1989 Zon LI, Dorfman DM, Orkin SH. The polymerase chain reaction colony miniprep Biotechniques. 7: 696-698. PMID 2631784  1
1989 Dorfman DM, Zon LI, Orkin SH. Rapid amplification of lambda gt11 bacteriophage library inserts from plaques using the polymerase chain reaction (PCR) Biotechniques. 7. PMID 2534350  1
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