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Leonard I. Zon, M.D. - Publications

Affiliations: 
Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
Genetics, Chemical Engineering, Human Development
Website:
https://hsci.harvard.edu/people/leonard-i-zon-md
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332 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Rossmann MP, Zon LI. 'Enhancing' red cell fate through epigenetic mechanisms. Current Opinion in Hematology. PMID 33741760 DOI: 10.1097/MOH.0000000000000654  0.36
2021 Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, ... ... Zon LI, et al. Melanoma models for the next generation of therapies. Cancer Cell. PMID 33545064 DOI: 10.1016/j.ccell.2021.01.011  0.52
2021 Fazio M, van Rooijen E, Dang M, van de Hoek G, Ablain J, Mito JK, Yang S, Thomas A, Michael J, Fabo T, Modhurima R, Pessina P, Kaufman CK, Zhou Y, White RM, ... Zon LI, et al. SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance. Elife. 10. PMID 33527896 DOI: 10.7554/eLife.64370  1
2021 Ablain J, Liu S, Moriceau G, Lo RS, Zon LI. SPRED1 deletion confers resistance to MAPK inhibition in melanoma. The Journal of Experimental Medicine. 218. PMID 33306107 DOI: 10.1084/jem.20201097  0.48
2020 Choudhuri A, Trompouki E, Abraham BJ, Colli LM, Kock KH, Mallard W, Yang ML, Vinjamur DS, Ghamari A, Sporrij A, Hoi K, Hummel B, Boatman S, Chan V, Tseng S, ... ... Zon LI, et al. Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits. Nature Genetics. PMID 33230299 DOI: 10.1038/s41588-020-00738-2  1
2020 Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP, ... ... Zon LI, et al. Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Science Translational Medicine. 12. PMID 33087503 DOI: 10.1126/scitranslmed.abb5831  0.52
2020 Fazio M, van Rooijen E, Mito JK, Modhurima R, Weiskopf E, Yang S, Zon LI. Recurrent co-alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis. Pigment Cell & Melanoma Research. PMID 33064882 DOI: 10.1111/pcmr.12937  0.48
2020 Hsu J, Huang HT, Lee CT, Choudhuri A, Wilson NK, Abraham BJ, Moignard V, Kucinski I, Yu S, Hyde RK, Tober J, Cai X, Li Y, Guo Y, Yang S, ... ... Zon LI, et al. CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32883883 DOI: 10.1073/pnas.2003228117  1
2020 Minnoye L, Taskiran II, Mauduit D, Fazio M, Van Aerschot L, Hulselmans G, Christiaens V, Makhzami S, Seltenhammer M, Karras P, Primot A, Cadieu E, van Rooijen E, Marine JC, Egidy G, ... ... Zon L, et al. Cross-species analysis of enhancer logic using deep learning. Genome Research. PMID 32732264 DOI: 10.1101/gr.260844.120  0.4
2020 Choi J, Zhang T, Vu A, Ablain J, Makowski MM, Colli LM, Xu M, Hennessey RC, Yin J, Rothschild H, Gräwe C, Kovacs MA, Funderburk KM, Brossard M, Taylor J, ... ... Zon LI, et al. Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma. Nature Communications. 11: 2718. PMID 32483191 DOI: 10.1038/s41467-020-16590-1  0.48
2020 Makarova N, Kalaparthi V, Wang A, Williams C, Dokukin ME, Kaufman CK, Zon L, Sokolov I. Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish. Journal of the Mechanical Behavior of Biomedical Materials. 107: 103746. PMID 32364948 DOI: 10.1016/j.jmbbm.2020.103746  0.52
2020 Chen MJ, Lummertz da Rocha E, Cahan P, Kubaczka C, Hunter P, Sousa P, Mullin NK, Fujiwara Y, Nguyen M, Tan Y, Landry S, Han A, Yang S, Lu YF, Jha DK, ... ... Zon LI, et al. Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System. Stem Cell Reports. PMID 32302558 DOI: 10.1016/j.stemcr.2020.03.020  1
2020 Kato S, Weng QY, Insco ML, Chen KY, Muralidhar S, Pozniak J, Diaz JMS, Drier Y, Nguyen N, Lo JA, van Rooijen E, Kemeny LV, Zhan Y, Feng Y, Silkworth W, ... ... Zon LI, et al. Gain-of-function genetic alterations of G9a drive oncogenesis. Cancer Discovery. PMID 32269030 DOI: 10.1158/2159-8290.CD-19-0532  0.4
2020 Fazio M, Ablain J, Chuan Y, Langenau DM, Zon LI. Zebrafish patient avatars in cancer biology and precision cancer therapy. Nature Reviews. Cancer. 20: 263-273. PMID 32251397 DOI: 10.1038/s41568-020-0252-3  0.48
2020 Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Custo Greig E, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Abraham BJ, Kalocsay M, ... ... Zon LI, et al. RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nature Cell Biology. PMID 32231306 DOI: 10.1038/s41556-020-0493-0  0.48
2019 Jurynec MJ, Bai X, Bisgrove BW, Jackson H, Nechiporuk A, Palu RAS, Grunwald HA, Su YC, Hoshijima K, Yost HJ, Zon LI, Grunwald DJ. The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors. Development (Cambridge, England). PMID 31784460 DOI: 10.1242/dev.180133  1
2019 Morad G, Carman CV, Hagedorn EJ, Perlin JR, Zon LI, Mustafaoglu N, Park TE, Ingber DE, Daisy CC, Moses MA. Tumor-Derived Extracellular Vesicles Breach the Intact Blood Brain Barrier via Transcytosis. Acs Nano. PMID 31479239 DOI: 10.1021/acsnano.9b04397  0.48
2019 Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. PMID 31435017 DOI: 10.1038/s41586-019-1489-4  1
2019 Tyrkalska SD, Pérez-Oliva AB, Rodríguez-Ruiz L, Martínez-Morcillo FJ, Alcaraz-Pérez F, Martínez-Navarro FJ, Lachaud C, Ahmed N, Schroeder T, Pardo-Sánchez I, Candel S, López-Muñoz A, Choudhuri A, Rossmann MP, Zon LI, et al. Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1. Immunity. PMID 31174991 DOI: 10.1016/j.immuni.2019.05.005  0.36
2019 Cagan RL, Zon LI, White RM. Modeling Cancer with Flies and Fish. Developmental Cell. 49: 317-324. PMID 31063751 DOI: 10.1016/j.devcel.2019.04.013  0.52
2019 Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, ... ... Zon LI, et al. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science (New York, N.Y.). PMID 30705153 DOI: 10.1126/science.aav1749  0.56
2019 Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Aravena M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, et al. Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. PMID 30641053 DOI: 10.1053/j.gastro.2019.01.010  1
2018 Ablain J, Xu M, Rothschild H, Jordan RC, Mito JK, Daniels BH, Bell CF, Joseph NM, Wu H, Bastian BC, Zon LI, Yeh I. Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma. Science (New York, N.Y.). PMID 30385465 DOI: 10.1126/science.aau6509  0.48
2018 Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, et al. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. The Journal of Biological Chemistry. PMID 30366982 DOI: 10.1074/jbc.RA118.002742  1
2018 Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, ... ... Zon LI, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proceedings of the National Academy of Sciences of the United States of America. PMID 30139917 DOI: 10.1073/pnas.1806077115  1
2018 Mansour MR, He S, Li Z, Lobbardi R, Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, Blonquist T, Gjini E, Gutierrez A, Tang Q, Garcia-Perez L, ... ... Zon LI, et al. JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. The Journal of Experimental Medicine. PMID 29941549 DOI: 10.1084/jem.20170484  0.48
2018 Kapp FG, Perlin JR, Hagedorn EJ, Gansner JM, Schwarz DE, O'Connell LA, Johnson NS, Amemiya C, Fisher DE, Wölfle U, Trompouki E, Niemeyer CM, Driever W, Zon LI. Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. PMID 29899448 DOI: 10.1038/s41586-018-0213-0  1
2018 McConnell AM, Mito JK, Ablain J, Dang M, Formichella L, Fisher DE, Zon LI. Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion. Developmental Biology. PMID 29883661 DOI: 10.1016/j.ydbio.2018.05.026  0.48
2018 Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MR, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, ... ... Zon LI, et al. Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma. Cancer Cell. 33: 785. PMID 29634951 DOI: 10.1016/j.ccell.2018.03.009  0.4
2018 Bennett AH, O'Donohue MF, Gundry SR, Chan AT, Widrick J, Draper I, Chakraborty A, Zhou Y, Zon LI, Gleizes PE, Beggs AH, Gupta VA. RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes. Plos Genetics. 14: e1007226. PMID 29518074 DOI: 10.1371/journal.pgen.1007226  0.48
2018 Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MS, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, ... ... Zon LI, et al. Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma. Cancer Cell. 33: 322-336.e8. PMID 29438700 DOI: 10.1016/j.ccell.2018.01.002  0.4
2018 Yu SH, Zhu KY, Zhang F, Wang J, Yuan H, Chen Y, Jin Y, Dong M, Wang L, Jia XE, Gao L, Dong ZW, Ren CG, Chen LT, Huang QH, ... ... Zon LI, et al. The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Biochimica Et Biophysica Acta. PMID 29378332 DOI: 10.1016/j.bbagrm.2017.12.009  0.48
2017 Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. Elife. 6. PMID 29117894 DOI: 10.7554/eLife.22626  0.52
2017 Crawford NG, Kelly DE, Hansen MEB, Beltrame MH, Fan S, Bowman SL, Jewett E, Ranciaro A, Thompson S, Lo Y, Pfeifer SP, Jensen JD, Campbell MC, Beggs W, Hormozdiari F, ... ... Zon L, et al. Loci associated with skin pigmentation identified in African populations. Science (New York, N.Y.). PMID 29025994 DOI: 10.1126/science.aan8433  1
2017 Fazio M, Zon LI. Fishing for answers in precision cancer medicine. Proceedings of the National Academy of Sciences of the United States of America. PMID 28916734 DOI: 10.1073/pnas.1713769114  0.4
2017 Ciarlo C, Kaufman CK, Kinikoglu B, Michael J, Yang S, D Amato C, Blokzijl-Franke S, den Hertog J, Schlaeger TM, Zhou Y, Liao E, Zon LI. A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. Elife. 6. PMID 28832322 DOI: 10.7554/eLife.29145  0.52
2017 Perlin JR, Robertson AL, Zon LI. Efforts to enhance blood stem cell engraftment: Recent insights from zebrafish hematopoiesis. The Journal of Experimental Medicine. PMID 28830909 DOI: 10.1084/jem.20171069  0.4
2017 Perlin JR, Sporrij A, Zon LI. Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment. Journal of Molecular Medicine (Berlin, Germany). PMID 28702683 DOI: 10.1007/s00109-017-1559-8  0.4
2017 Khajavi M, Zhou Y, Birsner AE, Bazinet L, Di Sant AR, Schiffer AJ, Rogers MS, Krishnaji ST, Hu B, Nguyen V, Zon L, D'Amato RJ. Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice. Plos Genetics. 13: e1006848. PMID 28617813 DOI: 10.1371/journal.pgen.1006848  0.48
2017 Fazio M, Avagyan S, van Rooijen E, Mannherz W, Kaufman CK, Lobbardi R, Langenau DM, Zon LI. Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors. Zebrafish. PMID 28557653 DOI: 10.1089/zeb.2017.1434  0.52
2017 Theodore LN, Hagedorn EJ, Cortes M, Natsuhara K, Liu SY, Perlin JR, Yang S, Daily ML, Zon LI, North TE. Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization. Stem Cell Reports. PMID 28416284 DOI: 10.1016/j.stemcr.2017.03.016  1
2017 Hockman D, Burns A, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PD, Lickert H, et al. Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. Elife. 6. PMID 28387645 DOI: 10.7554/eLife.21231  0.52
2017 van Rooijen E, Fazio M, Zon LI. From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics. Pigment Cell & Melanoma Research. PMID 28379616 DOI: 10.1111/pcmr.12592  0.4
2017 Blaser BW, Moore JL, Hagedorn EJ, Li B, Riquelme R, Lichtig A, Yang S, Zhou Y, Tamplin OJ, Binder V, Zon LI. CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of Experimental Medicine. PMID 28351983 DOI: 10.1084/jem.20161616  1
2017 Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, ... ... Zon LI, et al. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Science Translational Medicine. 9. PMID 28179501 DOI: 10.1126/scitranslmed.aah5645  1
2017 Volpi S, Yamazaki Y, Brauer PM, van Rooijen E, Hayashida A, Slavotinek A, Sun Kuehn H, Di Rocco M, Rivolta C, Bortolomai I, Du L, Felgentreff K, Ott de Bruin L, Hayashida K, Freedman G, ... ... Zon L, et al. EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. The Journal of Experimental Medicine. PMID 28148688 DOI: 10.1084/jem.20161525  0.48
2017 Gansner JM, Leung AD, Superdock M, Blair MC, Ammerman MB, Durand EM, Barut B, Handin RI, Stachura DL, Lu C, Springer TA, Zon LI. Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity. Blood. PMID 28126924 DOI: 10.1182/blood-2016-12-759993  0.48
2016 van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, ... ... Zon LI, et al. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American Journal of Human Genetics. PMID 28017375 DOI: 10.1016/j.ajhg.2016.11.016  1
2016 Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L. Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nature Cell Biology. PMID 27870830 DOI: 10.1038/ncb3444  0.56
2016 Rossmann MP, Zhou Y, Zon LI. Development: For cloche the Bell Tolls. Current Biology : Cb. 26: R890-R892. PMID 27728792 DOI: 10.1016/j.cub.2016.08.009  0.48
2016 Yang S, Ott CJ, Rossmann MP, Superdock M, Zon LI, Zhou Y. Chromatin immunoprecipitation and an open chromatin assay in zebrafish erythrocytes. Methods in Cell Biology. 135: 387-412. PMID 27443937 DOI: 10.1016/bs.mcb.2016.04.019  0.48
2016 Ablain J, Zon LI. Tissue-specific gene targeting using CRISPR/Cas9. Methods in Cell Biology. 135: 189-202. PMID 27443926 DOI: 10.1016/bs.mcb.2016.03.004  0.48
2016 Burberry A, Suzuki N, Wang JY, Moccia R, Mordes DA, Stewart MH, Suzuki-Uematsu S, Ghosh S, Singh A, Merkle FT, Koszka K, Li QZ, Zon L, Rossi DJ, Trowbridge JJ, et al. Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. Science Translational Medicine. 8: 347ra93. PMID 27412785 DOI: 10.1126/scitranslmed.aaf6038  1
2016 Ray MK, Wiskow O, King MJ, Ismail N, Ergun A, Wang Y, Plys AJ, Davis CP, Kathrein K, Sadreyev R, Borowsky ML, Eggan K, Zon L, Galloway JL, Kingston RE. CAT7 and cat7l long non-coding RNAs Tune Polycomb Repressive Complex 1 Function During Human and Zebrafish Development. The Journal of Biological Chemistry. PMID 27405765 DOI: 10.1074/jbc.M116.730853  1
2016 Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI. Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. Journal of Visualized Experiments : Jove. PMID 27341538 DOI: 10.3791/54168  0.48
2016 Rowe RG, Mandelbaum J, Zon LI, Daley GQ. Engineering Hematopoietic Stem Cells: Lessons from Development. Cell Stem Cell. 18: 707-20. PMID 27257760 DOI: 10.1016/j.stem.2016.05.016  1
2016 Dang M, Fogley R, Zon LI. Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish. Advances in Experimental Medicine and Biology. 916: 103-24. PMID 27165351 DOI: 10.1007/978-3-319-30654-4_5  1
2016 Svoboda O, Stachura DL, Machonova O, Zon LI, Traver D, Bartunek P. Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nature Protocols. 11: 1007-20. PMID 27123951 DOI: 10.1038/nprot.2016.053  0.56
2016 Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... ... Zon LI, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/j.molcel.2016.03.013  1
2016 Avagyan S, Zon LI. FISH TO LEARN: INSIGHTS INTO BLOOD DEVELOPMENT AND BLOOD DISORDERS FROM ZEBRAFISH HEMATOPOIESIS. Human Gene Therapy. PMID 27018965 DOI: 10.1089/hum.2016.024  1
2016 Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, ... ... Zon LI, et al. A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science (New York, N.Y.). 351: aad2197. PMID 26823433 DOI: 10.1126/science.aad2197  1
2016 Huang J, Liu X, Li D, Shao Z, Cao H, Zhang Y, Trompouki E, Bowman TV, Zon LI, Yuan GC, Orkin SH, Xu J. Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. Developmental Cell. 36: 9-23. PMID 26766440 DOI: 10.1016/j.devcel.2015.12.014  1
2015 Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, ... ... Zon LI, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. PMID 26607381 DOI: 10.1016/j.stem.2015.09.015  0.44
2015 Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, ... ... Zon LI, et al. Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. Blood. PMID 26385351 DOI: 10.1182/blood-2015-07-659276  1
2015 Mosimann C, Panáková D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, ... Zon LI, et al. Chamber identity programs drive early functional partitioning of the heart. Nature Communications. 6: 8146. PMID 26306682 DOI: 10.1038/ncomms9146  1
2015 Heilmann S, Ratnakumar K, Langdon E, Kansler E, Kim I, Campbell NR, Perry E, McMahon A, Kaufman C, van Rooijen E, Lee W, Iacobuzio-Donahue C, Hynes R, Zon L, Xavier J, et al. A quantitative system for studying metastasis using transparent zebrafish. Cancer Research. PMID 26282170 DOI: 10.1158/0008-5472.CAN-14-3319  1
2015 Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 523: 468-71. PMID 26201599 DOI: 10.1038/nature14569  1
2015 Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, ... ... Zon LI, et al. Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Research. PMID 26138676 DOI: 10.1038/cr.2015.81  0.48
2015 Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Zhu W, Peng J, ... ... Zon LI, et al. TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. Plos Genetics. 11: e1005346. PMID 26131719 DOI: 10.1371/journal.pgen.1005346  0.48
2015 Peng X, Dong M, Ma L, Jia XE, Mao J, Jin C, Chen Y, Gao L, Liu X, Ma K, Wang L, Du T, Jin Y, Huang Q, Li K, ... Zon LI, et al. A point mutation of zebrafish c-cbl gene in the ring finger domain produces a phenotype mimicking human myeloproliferative disease. Leukemia. PMID 26104663 DOI: 10.1038/leu.2015.154  1
2015 Liu X, Jia X, Yuan H, Ma K, Chen Y, Jin Y, Deng M, Pan W, Chen S, Chen Z, de The H, Zon LI, Zhou Y, Zhou J, Zhu J. DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. Journal of Hematology & Oncology. 8: 15. PMID 25886310 DOI: 10.1186/s13045-015-0115-7  1
2015 Kim PG, Nakano H, Das PP, Chen MJ, Rowe RG, Chou SS, Ross SJ, Sakamoto KM, Zon LI, Schlaeger TM, Orkin SH, Nakano A, Daley GQ. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. The Journal of Experimental Medicine. 212: 633-48. PMID 25870201 DOI: 10.1084/jem.20141514  1
2015 Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, ... ... Zon LI, et al. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. The Journal of Experimental Medicine. 212: 649-63. PMID 25870200 DOI: 10.1084/jem.20141528  1
2015 Dang M, Zon LI. Screening for melanoma resistance genes in vivo. Pigment Cell & Melanoma Research. 28: 375-6. PMID 25818368 DOI: 10.1111/pcmr.12368  1
2015 Ablain J, Durand EM, Yang S, Zhou Y, Zon LI. A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish. Developmental Cell. 32: 756-64. PMID 25752963 DOI: 10.1016/j.devcel.2015.01.032  0.48
2015 Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC, Orkin SH, ... ... Zon LI, et al. Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. Elife. 4. PMID 25714926 DOI: 10.7554/eLife.05544  1
2015 Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell. 160: 241-52. PMID 25594182 DOI: 10.1016/j.cell.2014.12.032  1
2015 Jang IH, Lu YF, Zhao L, Wenzel PL, Kume T, Datta SM, Arora N, Guiu J, Lagha M, Kim PG, Do EK, Kim JH, Schlaeger TM, Zon LI, Bigas A, et al. Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood. 125: 1418-26. PMID 25587036 DOI: 10.1182/blood-2014-04-568170  1
2015 Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, et al. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Molecular and Cellular Biology. 35: 789-804. PMID 25512612 DOI: 10.1128/MCB.00971-14  1
2015 Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, ... ... Zon LI, et al. A comparison of non-integrating reprogramming methods. Nature Biotechnology. 33: 58-63. PMID 25437882 DOI: 10.1038/nbt.3070  1
2015 Musso G, Mosimann C, Panáková D, Burger A, Zhou Y, Zon LI, MacRae CA. Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators Genomics Data. 6: 199-201. DOI: 10.1016/j.gdata.2015.09.015  1
2014 Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic Acids Research. 42: 11777-91. PMID 25223788 DOI: 10.1093/nar/gku805  0.44
2014 Hagedorn EJ, Durand EM, Fast EM, Zon LI. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. Experimental Cell Research. 329: 220-6. PMID 25094063 DOI: 10.1016/j.yexcr.2014.07.030  1
2014 Guo C, Chen X, Song H, Maynard MA, Zhou Y, Lobanov AV, Gladyshev VN, Ganis JJ, Wiley D, Jugo RH, Lee NY, Castroneves LA, Zon LI, Scanlan TS, Feldman HA, et al. Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. Endocrinology. 155: 4069-80. PMID 25004091 DOI: 10.1210/en.2013-2029  0.6
2014 Svoboda O, Stachura DL, Machoňová O, Pajer P, Brynda J, Zon LI, Traver D, Bartůněk P. Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 124: 220-8. PMID 24869937 DOI: 10.1182/blood-2014-03-564682  1
2014 Mirabello L, Macari ER, Jessop L, Ellis SR, Myers T, Giri N, Taylor AM, McGrath KE, Humphries JM, Ballew BJ, Yeager M, Boland JF, He J, Hicks BD, Burdett L, ... ... Zon L, et al. Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families. Blood. 124: 24-32. PMID 24829207 DOI: 10.1182/blood-2013-11-540278  1
2014 Kong Y, Grimaldi M, Curtin E, Dougherty M, Kaufman C, White RM, Zon LI, Liao EC. Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation. Chemistry & Biology. 21: 488-501. PMID 24684905 DOI: 10.1016/j.chembiol.2014.02.013  1
2014 Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry BJ, Mochida GH, Hill RS, Weimer JM, Stein Q, Poduri A, Partlow JN, Ville D, Dulac O, Yu TW, ... ... Zon LI, et al. Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. American Journal of Human Genetics. 94: 547-58. PMID 24656866 DOI: 10.1016/j.ajhg.2014.03.003  1
2014 Hagedorn EJ, Zon LI. Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones. The Journal of Experimental Medicine. 211: 384-5. PMID 24616474 DOI: 10.1084/jem.2113insight2  1
2014 Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, MacRae CA. Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development (Cambridge, England). 141: 224-35. PMID 24346703 DOI: 10.1242/dev.099796  1
2013 Paik EJ, Mahony S, White RM, Price EN, Dibiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI. A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 1: 425-36. PMID 24286030 DOI: 10.1016/j.stemcr.2013.10.001  1
2013 Ablain J, Zon LI. Of fish and men: using zebrafish to fight human diseases. Trends in Cell Biology. 23: 584-6. PMID 24275383 DOI: 10.1016/j.tcb.2013.09.009  0.48
2013 Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature Cell Biology. 15: 1516-25. PMID 24240475 DOI: 10.1038/ncb2870  1
2013 Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell. 155: 909-21. PMID 24209627 DOI: 10.1016/j.cell.2013.10.023  1
2013 Chen CH, Durand E, Wang J, Zon LI, Poss KD. zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development (Cambridge, England). 140: 4988-97. PMID 24198277 DOI: 10.1242/dev.102053  1
2013 Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, ... ... Zon LI, et al. The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome Biology. 14: R113. PMID 24148783 DOI: 10.1186/gb-2013-14-10-r113  1
2013 Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D. The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 122: 3918-28. PMID 24128862 DOI: 10.1182/blood-2012-12-475392  1
2013 Doulatov S, Vo LT, Chou SS, Kim PG, Arora N, Li H, Hadland BK, Bernstein ID, Collins JJ, Zon LI, Daley GQ. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell. 13: 459-70. PMID 24094326 DOI: 10.1016/j.stem.2013.09.002  1
2013 Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, ... ... Zon LI, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/blood-2013-05-503177  1
2013 Boatman S, Barrett F, Satishchandran S, Jing L, Shestopalov I, Zon LI. Assaying hematopoiesis using zebrafish. Blood Cells, Molecules & Diseases. 51: 271-6. PMID 23916372 DOI: 10.1016/j.bcmd.2013.07.009  1
2013 Storer NY, White RM, Uong A, Price E, Nielsen GP, Langenau DM, Zon LI. Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. Development (Cambridge, England). 140: 3040-50. PMID 23821038 DOI: 10.1242/dev.087858  1
2013 Mosimann C, Puller AC, Lawson KL, Tschopp P, Amsterdam A, Zon LI. Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 949-63. PMID 23723152 DOI: 10.1002/dvdy.23989  1
2013 Albacker CE, Storer NY, Langdon EM, Dibiase A, Zhou Y, Langenau DM, Zon LI. The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish. Plos One. 8: e64969. PMID 23705022 DOI: 10.1371/journal.pone.0064969  1
2013 Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills AA, DiBiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, Zon LI. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development (Cambridge, England). 140: 2354-64. PMID 23615277 DOI: 10.1242/dev.088427  1
2013 Kim PG, Albacker CE, Lu YF, Jang IH, Lim Y, Heffner GC, Arora N, Bowman TV, Lin MI, Lensch MW, De Los Angeles A, Zon LI, Loewer S, Daley GQ. Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proceedings of the National Academy of Sciences of the United States of America. 110: E141-50. PMID 23236128 DOI: 10.1073/pnas.1214361110  1
2013 Jing CB, Chen Y, Dong M, Peng XL, Jia XE, Gao L, Ma K, Deng M, Liu TX, Zon LI, Zhu J, Zhou Y, Zhou Y. Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish. Developmental Biology. 374: 24-31. PMID 23220656 DOI: 10.1016/j.ydbio.2012.11.032  0.48
2013 Bai X, Trowbridge JJ, Riley E, Lee JA, DiBiase A, Kaartinen VM, Orkin SH, Zon LI. TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes. Developmental Biology. 373: 422-30. PMID 23159334 DOI: 10.1016/j.ydbio.2012.10.008  1
2013 Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, et al. Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Developmental Biology. 373: 431-41. PMID 22960038 DOI: 10.1016/j.ydbio.2012.08.015  1
2012 Tamplin OJ, White RM, Jing L, Kaufman CK, Lacadie SA, Li P, Taylor AM, Zon LI. Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 459-68. PMID 23801494 DOI: 10.1002/wdev.37  1
2012 McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon EM, Lengerke C, Zon LI, Collins JJ, Daley GQ. The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell. 11: 701-14. PMID 23122293 DOI: 10.1016/j.stem.2012.07.018  1
2012 Mochida GH, Ganesh VS, de Michelena MI, Dias H, Atabay KD, Kathrein KL, Huang HT, Hill RS, Felie JM, Rakiec D, Gleason D, Hill AD, Malik AN, Barry BJ, Partlow JN, ... ... Zon LI, et al. CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nature Genetics. 44: 1260-4. PMID 23023333 DOI: 10.1038/ng.2425  1
2012 Jing L, Durand EM, Ezzio C, Pagliuca SM, Zon LI. In situ hybridization assay-based small molecule screening in zebrafish. Current Protocols in Chemical Biology. 4. PMID 23001521 DOI: 10.1002/9780470559277.ch110236  0.48
2012 Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, ... ... Zon LI, et al. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell. 150: 1135-46. PMID 22980977 DOI: 10.1016/j.cell.2012.07.033  1
2012 Gupta VA, Kawahara G, Myers JA, Chen AT, Hall TE, Manzini MC, Currie PD, Zhou Y, Zon LI, Kunkel LM, Beggs AH. A splice site mutation in laminin-α2 results in a severe muscular dystrophy and growth abnormalities in zebrafish. Plos One. 7: e43794. PMID 22952766 DOI: 10.1371/journal.pone.0043794  1
2012 Sorrells S, Carbonneau S, Harrington E, Chen AT, Hast B, Milash B, Pyati U, Major MB, Zhou Y, Zon LI, Stewart RA, Look AT, Jette C. Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53. Plos Genetics. 8: e1002922. PMID 22952453 DOI: 10.1371/journal.pgen.1002922  1
2012 Oubaha M, Lin MI, Margaron Y, Filion D, Price EN, Zon LI, Côté JF, Gratton JP. Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. Blood. 120: 3371-81. PMID 22936663 DOI: 10.1182/blood-2012-03-419721  1
2012 de Jong JL, Zon LI. Histocompatibility and hematopoietic transplantation in the zebrafish. Advances in Hematology. 2012: 282318. PMID 22778744 DOI: 10.1155/2012/282318  0.56
2012 Ganis JJ, Hsia N, Trompouki E, de Jong JL, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, Zon LI. Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Developmental Biology. 366: 185-94. PMID 22537494 DOI: 10.1016/j.ydbio.2012.03.021  1
2012 Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI. Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental Cell. 22: 625-38. PMID 22421047 DOI: 10.1016/j.devcel.2012.01.003  1
2012 Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, ... Zon LI, et al. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Molecular Cell. 45: 330-43. PMID 22325351 DOI: 10.1016/j.molcel.2011.11.032  1
2012 Bowman TV, Trompouki E, Zon LI. Linking hematopoietic regeneration to developmental signaling pathways: a story of BMP and Wnt. Cell Cycle (Georgetown, Tex.). 11: 424-5. PMID 22262185 DOI: 10.4161/cc.11.3.19161  1
2012 Brown KH, Dobrinski KP, Lee AS, Gokcumen O, Mills RE, Shi X, Chong WW, Chen JY, Yoo P, David S, Peterson SM, Raj T, Choy KW, Stranger BE, Williamson RE, ... Zon LI, et al. Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis. Proceedings of the National Academy of Sciences of the United States of America. 109: 529-34. PMID 22203992 DOI: 10.1073/pnas.1112163109  1
2012 Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP. An optical platform for cell tracking in adult zebrafish. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 176-82. PMID 22162445 DOI: 10.1002/cyto.a.21167  1
2012 Taylor AM, Humphries JM, White RM, Murphey RD, Burns CE, Zon LI. Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Experimental Hematology. 40: 228-237.e5. PMID 22120640 DOI: 10.1016/j.exphem.2011.11.007  1
2012 Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP. In vivo cell tracking and quantification method in adult zebrafish Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8225. DOI: 10.1117/12.909632  1
2011 Detrich HW, Westerfield M, Zon LI. The zebrafish. Preface. Methods in Cell Biology. 105: xxi-xxii. PMID 22043535  1
2011 Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu DC, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand EM, Mosimann C, Heffner GC, Daley GQ, ... ... Zon LI, et al. Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell. 147: 577-89. PMID 22036566 DOI: 10.1016/j.cell.2011.09.044  1
2011 Li P, White RM, Zon LI. Transplantation in zebrafish. Methods in Cell Biology. 105: 403-17. PMID 21951540 DOI: 10.1016/B978-0-12-381320-6.00017-5  1
2011 Bugeon L, Taylor HB, Progatzky F, Lin MI, Ellis CD, Welsh N, Smith E, Vargesson N, Gray C, Renshaw SA, Chico TJ, Zon LI, Lamb J, Dallman MJ. The NOTCH pathway contributes to cell fate decision in myelopoiesis. Haematologica. 96: 1753-60. PMID 21933862 DOI: 10.3324/haematol.2011.044115  1
2011 Trompouki E, Bowman TV, Dibiase A, Zhou Y, Zon LI. Chromatin immunoprecipitation in adult zebrafish red cells. Methods in Cell Biology. 104: 341-52. PMID 21924172 DOI: 10.1016/B978-0-12-374814-0.00019-7  1
2011 Zhou Y, Zon LI. The zon laboratory guide to positional cloning in zebrafish. Methods in Cell Biology. 104: 287-309. PMID 21924169 DOI: 10.1016/B978-0-12-374814-0.00016-1  0.48
2011 Mosimann C, Zon LI. Advanced zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments. Methods in Cell Biology. 104: 173-94. PMID 21924163 DOI: 10.1016/B978-0-12-374814-0.00010-0  0.52
2011 Bai X, Yang Z, Jiang H, Lin S, Zon LI. Genetic suppressor screens in haploids. Methods in Cell Biology. 104: 129-36. PMID 21924160 DOI: 10.1016/B978-0-12-374814-0.00007-0  1
2011 Jing L, Zon LI. Zebrafish as a model for normal and malignant hematopoiesis. Disease Models & Mechanisms. 4: 433-8. PMID 21708900 DOI: 10.1242/dmm.006791  0.44
2011 Li P, Zon LI. Stem cell migration: a zebrafish model. Methods in Molecular Biology (Clifton, N.J.). 750: 157-68. PMID 21618090 DOI: 10.1007/978-1-61779-145-1_11  1
2011 Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, et al. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 8: 445-58. PMID 21474107 DOI: 10.1016/j.stem.2011.02.003  1
2011 Taylor AM, Zon LI. Modeling Diamond Blackfan anemia in the zebrafish. Seminars in Hematology. 48: 81-8. PMID 21435504 DOI: 10.1053/j.seminhematol.2011.02.002  0.44
2011 White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, ... ... Zon LI, et al. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature. 471: 518-22. PMID 21430780 DOI: 10.1038/nature09882  1
2011 Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, ... ... Zon LI, et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 471: 513-7. PMID 21430779 DOI: 10.1038/nature09806  1
2011 Stachura DL, Svoboda O, Lau RP, Balla KM, Zon LI, Bartunek P, Traver D. Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood. 118: 1274-82. PMID 21415264 DOI: 10.1182/blood-2011-01-331199  1
2011 de Jong JL, Burns CE, Chen AT, Pugach E, Mayhall EA, Smith AC, Feldman HA, Zhou Y, Zon LI. Characterization of immune-matched hematopoietic transplantation in zebrafish. Blood. 117: 4234-42. PMID 21346254 DOI: 10.1182/blood-2010-09-307488  1
2011 Alexander MS, Kawahara G, Kho AT, Howell MH, Pusack TJ, Myers JA, Montanaro F, Zon LI, Guyon JR, Kunkel LM. Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors. Muscle & Nerve. 43: 741-50. PMID 21337346 DOI: 10.1002/mus.21972  1
2011 Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT. cpsf1 is required for definitive HSC survival in zebrafish. Blood. 117: 3996-4007. PMID 21330472 DOI: 10.1182/blood-2010-08-304030  1
2011 Lacadie SA, Zon LI. The ERGonomics of hematopoietic stem cell self-renewal. Genes & Development. 25: 289-93. PMID 21325129 DOI: 10.1101/gad.2031511  1
2011 Gupta V, Kawahara G, Gundry SR, Chen AT, Lencer WI, Zhou Y, Zon LI, Kunkel LM, Beggs AH. The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Human Molecular Genetics. 20: 1712-25. PMID 21296866 DOI: 10.1093/hmg/ddr047  1
2011 Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, Zon LI. Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (Cambridge, England). 138: 169-77. PMID 21138979 DOI: 10.1242/dev.059345  1
2010 Durand EM, Zon LI. Stem cells: The blood balance. Nature. 468: 644-5. PMID 21124447 DOI: 10.1038/468644a  0.48
2010 Detrich HW, Westerfield M, Zon LI. The zebrafish: cellular and developmental biology, part A. Preface. Methods in Cell Biology. 100: xiii. PMID 21111211 DOI: 10.1016/B978-0-12-384892-5.00018-9  1
2010 Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, et al. T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell. 18: 353-66. PMID 20951945 DOI: 10.1016/j.ccr.2010.09.009  1
2010 North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 17315-20. PMID 20855591 DOI: 10.1073/pnas.1008209107  1
2010 Paik EJ, Zon LI. Hematopoietic development in the zebrafish. The International Journal of Developmental Biology. 54: 1127-37. PMID 20711990 DOI: 10.1387/ijdb.093042ep  1
2010 Storer NY, Zon LI. Zebrafish models of p53 functions. Cold Spring Harbor Perspectives in Biology. 2: a001123. PMID 20679337 DOI: 10.1101/cshperspect.a001123  0.84
2010 Tamplin OJ, Zon LI. Fishing at the cellular level. Nature Methods. 7: 600-1. PMID 20676080 DOI: 10.1038/nmeth0810-600  0.92
2010 Tamplin OJ, Zon LI. Blood flow: metalloproteases cut loose in primitive erythrocytes. Current Biology : Cb. 20: R561-2. PMID 20619808 DOI: 10.1016/j.cub.2010.05.014  0.92
2010 Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, ... Zon LI, et al. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 142: 133-43. PMID 20603019 DOI: 10.1016/j.cell.2010.05.028  1
2010 Koo S, Huntly BJ, Wang Y, Chen J, Brumme K, Ball B, McKinney-Freeman SL, Yabuuchi A, Scholl C, Bansal D, Zon LI, Fröhling S, Daley GQ, Gilliland DG, Mercher T. Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis. Haematologica. 95: 1642-50. PMID 20494928 DOI: 10.3324/haematol.2010.023168  1
2010 Durand EM, Zon LI. Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment. Current Opinion in Hematology. 17: 308-12. PMID 20473159 DOI: 10.1097/MOH.0b013e32833a888c  0.48
2010 Paik EJ, de Jong JL, Pugach E, Opara P, Zon LI. A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. Zebrafish. 7: 61-8. PMID 20415644 DOI: 10.1089/zeb.2009.0643  1
2010 Zon LI, Peterson R. The new age of chemical screening in zebrafish. Zebrafish. 7: 1. PMID 20415642 DOI: 10.1089/zeb.2010.9996  1
2010 de Jong JL, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, Zon LI. Interaction of retinoic acid and scl controls primitive blood development. Blood. 116: 201-9. PMID 20410509 DOI: 10.1182/blood-2009-10-249557  1
2010 Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (New York, N.Y.). 327: 1650-3. PMID 20339075 DOI: 10.1126/science.1186624  1
2010 Li P, Zon LI. Resolving the controversy about N-cadherin and hematopoietic stem cells. Cell Stem Cell. 6: 199-202. PMID 20207222 DOI: 10.1016/j.stem.2010.02.007  1
2010 Smith AC, Raimondi AR, Salthouse CD, Ignatius MS, Blackburn JS, Mizgirev IV, Storer NY, de Jong JL, Chen AT, Zhou Y, Revskoy S, Zon LI, Langenau DM. High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood. 115: 3296-303. PMID 20056790 DOI: 10.1182/blood-2009-10-246488  0.84
2009 Taylor AM, Zon LI. Zebrafish tumor assays: the state of transplantation. Zebrafish. 6: 339-46. PMID 20047467 DOI: 10.1089/zeb.2009.0607  0.44
2009 Dovey M, White RM, Zon LI. Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish. Zebrafish. 6: 397-404. PMID 19954345 DOI: 10.1089/zeb.2009.0606  0.52
2009 Kaufman CK, White RM, Zon L. Chemical genetic screening in the zebrafish embryo. Nature Protocols. 4: 1422-32. PMID 19745824 DOI: 10.1038/nprot.2009.144  1
2009 Dovey MC, Zon LI. Defining cancer stem cells by xenotransplantation in zebrafish. Methods in Molecular Biology (Clifton, N.J.). 568: 1-5. PMID 19582417 DOI: 10.1007/978-1-59745-280-9_1  0.48
2009 North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, Zon LI. Hematopoietic stem cell development is dependent on blood flow. Cell. 137: 736-48. PMID 19450519 DOI: 10.1016/j.cell.2009.04.023  1
2009 Stachura DL, Reyes JR, Bartunek P, Paw BH, Zon LI, Traver D. Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood. 114: 279-89. PMID 19433857 DOI: 10.1182/blood-2009-02-203638  1
2009 Dovey M, Patton EE, Bowman T, North T, Goessling W, Zhou Y, Zon LI. Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Molecular and Cellular Biology. 29: 3746-53. PMID 19380487 DOI: 10.1128/MCB.01684-08  0.48
2009 Burns CE, Galloway JL, Smith AC, Keefe MD, Cashman TJ, Paik EJ, Mayhall EA, Amsterdam AH, Zon LI. A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood. 113: 5776-82. PMID 19332767 DOI: 10.1182/blood-2008-12-193607  1
2009 Goessling W, North TE, Loewer S, Lord AM, Lee S, Stoick-Cooper CL, Weidinger G, Puder M, Daley GQ, Moon RT, Zon LI. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell. 136: 1136-47. PMID 19303855 DOI: 10.1016/j.cell.2009.01.015  1
2009 Fraenkel PG, Gibert Y, Holzheimer JL, Lattanzi VJ, Burnett SF, Dooley KA, Wingert RA, Zon LI. Transferrin-a modulates hepcidin expression in zebrafish embryos. Blood. 113: 2843-50. PMID 19047682 DOI: 10.1182/blood-2008-06-165340  1
2009 Freeman JL, Ceol C, Feng H, Langenau DM, Belair C, Stern HM, Song A, Paw BH, Look AT, Zhou Y, Zon LI, Lee C. Construction and application of a zebrafish array comparative genomic hybridization platform. Genes, Chromosomes & Cancer. 48: 155-70. PMID 18973135 DOI: 10.1002/gcc.20623  0.48
2008 Zon LI, Le X. Potential of zebrafish for anticancer drug screening. Expert Opinion On Drug Discovery. 3: 1451-60. PMID 23506108 DOI: 10.1517/17460440802580171  1
2008 Sessa AK, White R, Houvras Y, Burke C, Pugach E, Baker B, Gilbert R, Thomas Look A, Zon LI. The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio. Zebrafish. 5: 335-9. PMID 19133832 DOI: 10.1089/zeb.2008.0535  1
2008 Ceol CJ, Houvras Y, White RM, Zon LI. Melanoma biology and the promise of zebrafish. Zebrafish. 5: 247-55. PMID 19133823 DOI: 10.1089/zeb.2008.0544  0.52
2008 Huang HT, Zon LI. Regulation of stem cells in the zebra fish hematopoietic system. Cold Spring Harbor Symposia On Quantitative Biology. 73: 111-8. PMID 19022765 DOI: 10.1101/sqb.2008.73.029  0.96
2008 Imamura S, Uchiyama J, Koshimizu E, Hanai J, Raftopoulou C, Murphey RD, Bayliss PE, Imai Y, Burns CE, Masutomi K, Gagos S, Zon LI, Roberts TM, Kishi S. A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. Plos One. 3: e3364. PMID 18846223 DOI: 10.1371/journal.pone.0003364  1
2008 Wang L, Sewell WF, Kim SD, Shin JT, MacRae CA, Zon LI, Seidman JG, Seidman CE. Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development (Cambridge, England). 135: 3425-34. PMID 18799547 DOI: 10.1242/dev.012237  1
2008 White RM, Zon LI. Melanocytes in development, regeneration, and cancer. Cell Stem Cell. 3: 242-52. PMID 18786412 DOI: 10.1016/j.stem.2008.08.005  0.52
2008 Trede NS, Ota T, Kawasaki H, Paw BH, Katz T, Demarest B, Hutchinson S, Zhou Y, Hersey C, Zapata A, Amemiya CT, Zon LI. Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2575-84. PMID 18729230 DOI: 10.1002/dvdy.21683  1
2008 Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V. Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. Oncogene. 27: 5845-55. PMID 18641688 DOI: 10.1038/onc.2008.202  1
2008 Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, Bourque C, Strijbosch R, Haramis AP, Puder M, Clevers H, Moon RT, Zon LI. APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Developmental Biology. 320: 161-74. PMID 18585699 DOI: 10.1016/j.ydbio.2008.05.526  1
2008 Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI. montalcino, A zebrafish model for variegate porphyria. Experimental Hematology. 36: 1132-42. PMID 18550261 DOI: 10.1016/j.exphem.2008.04.008  1
2008 Bussmann J, Lawson N, Zon L, Schulte-Merker S, Ekker M, Mullins M, Postlethwait J, Westerfield M. Zebrafish VEGF receptors: A guideline to nomenclature Plos Genetics. 4. PMID 18516225 DOI: 10.1371/journal.pgen.1000064  1
2008 White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, Bourque C, Dovey M, Goessling W, Burns CE, Zon LI. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell. 2: 183-9. PMID 18371439 DOI: 10.1016/j.stem.2007.11.002  1
2008 Lengerke C, Schmitt S, Bowman TV, Jang IH, Maouche-Chretien L, McKinney-Freeman S, Davidson AJ, Hammerschmidt M, Rentzsch F, Green JB, Zon LI, Daley GQ. BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell. 2: 72-82. PMID 18371423 DOI: 10.1016/j.stem.2007.10.022  1
2008 Langenau DM, Keefe MD, Storer NY, Jette CA, Smith AC, Ceol CJ, Bourque C, Look AT, Zon LI. Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish. Oncogene. 27: 4242-8. PMID 18345029 DOI: 10.1038/onc.2008.56  1
2008 Deutsch EW, Ball CA, Berman JJ, Bova GS, Brazma A, Bumgarner RE, Campbell D, Causton HC, Christiansen JH, Daian F, Dauga D, Davidson DR, Gimenez G, Goo YA, Grimmond S, ... ... Zon LI, et al. Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE). Nature Biotechnology. 26: 305-12. PMID 18327244 DOI: 10.1038/nbt1391  1
2008 Orkin SH, Zon LI. SnapShot: Hematopoiesis Cell. 132. PMID 18295585 DOI: 10.1016/j.cell.2008.02.013  1
2008 Orkin SH, Zon LI. Hematopoiesis: An Evolving Paradigm for Stem Cell Biology Cell. 132: 631-644. PMID 18295580 DOI: 10.1016/j.cell.2008.01.025  1
2008 Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Combinatorial regulation of novel erythroid gene expression in zebrafish. Experimental Hematology. 36: 424-32. PMID 18243489 DOI: 10.1016/j.exphem.2007.11.015  0.88
2008 Burket CT, Montgomery JE, Thummel R, Kassen SC, LaFave MC, Langenau DM, Zon LI, Hyde DR. Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Transgenic Research. 17: 265-79. PMID 17968670 DOI: 10.1007/s11248-007-9152-5  1
2007 Lord AM, North TE, Zon LI. Prostaglandin E2: making more of your marrow. Cell Cycle (Georgetown, Tex.). 6: 3054-7. PMID 18075310 DOI: 10.4161/cc.6.24.5129  1
2007 Ceol CJ, Pellman D, Zon LI. APC and colon cancer: two hits for one. Nature Medicine. 13: 1286-7. PMID 17987022 DOI: 10.1038/nm1107-1286  1
2007 Bahary N, Goishi K, Stuckenholz C, Weber G, Leblanc J, Schafer CA, Berman SS, Klagsbrun M, Zon LI. Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood. 110: 3627-36. PMID 17698971 DOI: 10.1182/blood-2006-04-016378  0.36
2007 Steffen LS, Guyon JR, Vogel ED, Howell MH, Zhou Y, Weber GJ, Zon LI, Kunkel LM. The zebrafish runzel muscular dystrophy is linked to the titin gene. Developmental Biology. 309: 180-92. PMID 17678642 DOI: 10.1016/j.ydbio.2007.06.015  1
2007 Freeman JL, Adeniyi A, Banerjee R, Dallaire S, Maguire SF, Chi J, Ng BL, Zepeda C, Scott CE, Humphray S, Rogers J, Zhou Y, Zon LI, Carter NP, Yang F, et al. Definition of the zebrafish genome using flow cytometry and cytogenetic mapping. Bmc Genomics. 8: 195. PMID 17597531 DOI: 10.1186/1471-2164-8-195  1
2007 North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 447: 1007-11. PMID 17581586 DOI: 10.1038/nature05883  1
2007 Paffett-Lugassy N, Hsia N, Fraenkel PG, Paw B, Leshinsky I, Barut B, Bahary N, Caro J, Handin R, Zon LI. Functional conservation of erythropoietin signaling in zebrafish Blood. 110: 2718-2726. PMID 17579187 DOI: 10.1182/blood-2006-04-016535  1
2007 Pfaff KL, Straub CT, Chiang K, Bear DM, Zhou Y, Zon LI. The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization. Molecular and Cellular Biology. 27: 5887-97. PMID 17576815 DOI: 10.1128/MCB.00175-07  1
2007 Goessling W, North TE, Zon LI. Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors. Nature Methods. 4: 551-3. PMID 17572681 DOI: 10.1038/nmeth1059  1
2007 Goessling W, North TE, Zon LI. New waves of discovery: modeling cancer in zebrafish. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 2473-9. PMID 17557959 DOI: 10.1200/JCO.2006.08.9821  1
2007 Le X, Langenau DM, Keefe MD, Kutok JL, Neuberg DS, Zon LI. Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104: 9410-5. PMID 17517602 DOI: 10.1073/pnas.0611302104  1
2007 Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI. Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & Development. 21: 1382-95. PMID 17510286 DOI: 10.1101/gad.1545007  1
2007 Trede NS, Medenbach J, Damianov A, Hung LH, Weber GJ, Paw BH, Zhou Y, Hersey C, Zapata A, Keefe M, Barut BA, Stuart AB, Katz T, Amemiya CT, Zon LI, et al. Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America. 104: 6608-13. PMID 17416673 DOI: 10.1073/pnas.0701919104  0.48
2007 Steffen LS, Guyon JR, Vogel ED, Beltre R, Pusack TJ, Zhou Y, Zon LI, Kunkel LM. Zebrafish orthologs of human muscular dystrophy genes. Bmc Genomics. 8: 79. PMID 17374169 DOI: 10.1186/1471-2164-8-79  1
2007 Peng CY, Yajima H, Burns CE, Zon LI, Sisodia SS, Pfaff SL, Sharma K. Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron. 53: 813-27. PMID 17359917 DOI: 10.1016/j.neuron.2007.02.019  1
2007 Shepard JL, Amatruda JF, Finkelstein D, Ziai J, Finley KR, Stern HM, Chiang K, Hersey C, Barut B, Freeman JL, Lee C, Glickman JN, Kutok JL, Aster JC, Zon LI. A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes & Development. 21: 55-9. PMID 17210788 DOI: 10.1101/gad.1470407  1
2006 Burns CE, Zon LI. Homing sweet homing: odyssey of hematopoietic stem cells. Immunity. 25: 859-62. PMID 17174927 DOI: 10.1016/j.immuni.2006.11.006  1
2006 Murphey RD, Stern HM, Straub CT, Zon LI. A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chemical Biology & Drug Design. 68: 213-9. PMID 17105485 DOI: 10.1111/j.1747-0285.2006.00439.x  1
2006 Bansal D, Scholl C, Fröhling S, McDowell E, Lee BH, Döhner K, Ernst P, Davidson AJ, Daley GQ, Zon LI, Gilliland DG, Huntly BJ. Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proceedings of the National Academy of Sciences of the United States of America. 103: 16924-9. PMID 17068127 DOI: 10.1073/pnas.0604579103  1
2006 Hu G, Tang J, Zhang B, Lin Y, Hanai J, Galloway J, Bedell V, Bahary N, Han Z, Ramchandran R, Thisse B, Thisse C, Zon LI, Sukhatme VP. A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. Journal of Cell Science. 119: 4117-26. PMID 16968741 DOI: 10.1242/jcs.03179  0.56
2006 Murphey RD, Zon LI. Small molecule screening in the zebrafish. Methods (San Diego, Calif.). 39: 255-61. PMID 16877005 DOI: 10.1016/j.ymeth.2005.09.019  0.92
2006 Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, ... ... Zon LI, et al. Mitoferrin is essential for erythroid iron assimilation. Nature. 440: 96-100. PMID 16511496 DOI: 10.1038/nature04512  1
2006 Davidson AJ, Zon LI. The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Developmental Biology. 292: 506-18. PMID 16457800 DOI: 10.1016/j.ydbio.2006.01.003  1
2006 Protas ME, Hersey C, Kochanek D, Zhou Y, Wilkens H, Jeffery WR, Zon LI, Borowsky R, Tabin CJ. Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. Nature Genetics. 38: 107-11. PMID 16341223 DOI: 10.1038/ng1700  1
2006 Tang J, Hu G, Hanai J, Yadlapalli G, Lin Y, Zhang B, Galloway J, Bahary N, Sinha S, Thisse B, Thisse C, Jin JP, Zon LI, Sukhatme VP. A critical role for calponin 2 in vascular development. The Journal of Biological Chemistry. 281: 6664-72. PMID 16317011 DOI: 10.1074/jbc.M506991200  0.56
2006 MacDonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, Kalluri R. Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood. 107: 1908-15. PMID 16254142 DOI: 10.1182/blood-2005-05-1814  1
2005 Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI. Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature Chemical Biology. 1: 366-70. PMID 16372403  1
2005 Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes & Development. 19: 2331-42. PMID 16166372 DOI: 10.1101/gad.1337005  1
2005 Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, ... ... Zon LI, et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 102: 13194-9. PMID 16150706 DOI: 10.1073/pnas.0506583102  1
2005 Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Schmidt B, Paw BH, Shaw GC, Kingsley P, Palis J, ... ... Zon LI, et al. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature. 436: 1035-39. PMID 16110529 DOI: 10.1038/nature03887  1
2005 Lin HF, Traver D, Zhu H, Dooley K, Paw BH, Zon LI, Handin RI. Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood. 106: 3803-10. PMID 16099879 DOI: 10.1182/blood-2005-01-0179  0.56
2005 Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, Andrews NC. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metabolism. 1: 191-200. PMID 16054062 DOI: 10.1016/j.cmet.2005.01.003  0.44
2005 Shmukler BE, Kurschat CE, Ackermann GE, Jiang L, Zhou Y, Barut B, Stuart-Tilley AK, Zhao J, Zon LI, Drummond IA, Vandorpe DH, Paw BH, Alper SL. Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization. American Journal of Physiology. Renal Physiology. 289: F835-49. PMID 15914778 DOI: 10.1152/ajprenal.00122.2005  0.48
2005 Fraenkel PG, Traver D, Donovan A, Zahrieh D, Zon LI. Ferroportin1 is required for normal iron cycling in zebrafish Journal of Clinical Investigation. 115: 1532-1541. PMID 15902304 DOI: 10.1172/JCI23780  1
2005 Zhu H, Traver D, Davidson AJ, Dibiase A, Thisse C, Thisse B, Nimer S, Zon LI. Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Developmental Biology. 281: 256-69. PMID 15893977 DOI: 10.1016/j.ydbio.2005.01.034  1
2005 Akashi K, Traver D, Zon LI. The complex cartography of stem cell commitment. Cell. 121: 160-2. PMID 15851023 DOI: 10.1016/j.cell.2005.04.005  0.56
2005 Weber GJ, Choe SE, Dooley KA, Paffett-Lugassy NN, Zhou Y, Zon LI. Mutant-specific gene programs in the zebrafish. Blood. 106: 521-30. PMID 15827125 DOI: 10.1182/blood-2004-11-4541  1
2005 Schönberger J, Wang L, Shin JT, Kim SD, Depreux FF, Zhu H, Zon L, Pizard A, Kim JB, Macrae CA, Mungall AJ, Seidman JG, Seidman CE. Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nature Genetics. 37: 418-22. PMID 15735644 DOI: 10.1038/ng1527  1
2005 Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, ... Zon LI, et al. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Current Biology : Cb. 15: 249-54. PMID 15694309 DOI: 10.1016/j.cub.2005.01.031  0.92
2005 Zon LI, Peterson RT. In vivo drug discovery in the zebrafish. Nature Reviews. Drug Discovery. 4: 35-44. PMID 15688071 DOI: 10.1038/nrd1606  1
2005 Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT. tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proceedings of the National Academy of Sciences of the United States of America. 102: 407-12. PMID 15630097 DOI: 10.1073/pnas.0406252102  1
2005 Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Developmental Cell. 8: 109-16. PMID 15621534 DOI: 10.1016/j.devcel.2004.12.001  0.88
2005 Dooley KA, Davidson AJ, Zon LI. Zebrafish scl functions independently in hematopoietic and endothelial development. Developmental Biology. 277: 522-36. PMID 15617691 DOI: 10.1016/j.ydbio.2004.09.004  1
2005 Paffett-Lugassy NN, Zon LI. Analysis of hematopoietic development in the zebrafish. Methods in Molecular Medicine. 105: 171-98. PMID 15492396  1
2004 Wingert RA, Brownlie A, Galloway JL, Dooley K, Fraenkel P, Axe JL, Davidson AJ, Barut B, Noriega L, Sheng X, Zhou Y, Zon LI. The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development (Cambridge, England). 131: 6225-35. PMID 15563524 DOI: 10.1242/dev.01540  1
2004 Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y, Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT, et al. Hematopoietic gene expression profile in zebrafish kidney marrow. Proceedings of the National Academy of Sciences of the United States of America. 101: 16240-5. PMID 15520368 DOI: 10.1073/pnas.0407241101  0.48
2004 Davidson AJ, Zon LI. The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene. 23: 7233-46. PMID 15378083 DOI: 10.1038/sj.onc.1207943  1
2004 Ransom DG, Bahary N, Niss K, Traver D, Burns C, Trede NS, Paffett-Lugassy N, Saganic WJ, Lim CA, Hersey C, Zhou Y, Barut BA, Lin S, Kingsley PD, Palis J, ... ... Zon LI, et al. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. Plos Biology. 2: E237. PMID 15314655 DOI: 10.1371/journal.pbio.0020237  1
2004 Zon LI, Zoloth L, Kadereit S. Taking the stem cell debate to the public. Plos Biology. 2: e188. PMID 15208732 DOI: 10.1371/journal.pbio.0020188  1
2004 Bovenkamp DE, Goishi K, Bahary N, Davidson AJ, Zhou Y, Becker T, Becker CG, Zon LI, Klagsbrun M. Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish. Gene Expression Patterns : Gep. 4: 361-70. PMID 15183302 DOI: 10.1016/j.modgep.2004.01.014  1
2004 Traver D, Winzeler A, Stern HM, Mayhall EA, Langenau DM, Kutok JL, Look AT, Zon LI. Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood. 104: 1298-305. PMID 15142873 DOI: 10.1182/blood-2004-01-0100  0.56
2004 Langenau DM, Ferrando AA, Traver D, Kutok JL, Hezel JP, Kanki JP, Zon LI, Look AT, Trede NS. In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 101: 7369-74. PMID 15123839 DOI: 10.1073/pnas.0402248101  0.56
2004 Trede NS, Langenau DM, Traver D, Look AT, Zon LI. The use of zebrafish to understand immunity. Immunity. 20: 367-79. PMID 15084267 DOI: 10.1016/S1074-7613(04)00084-6  0.56
2004 Hsu K, Traver D, Kutok JL, Hagen A, Liu TX, Paw BH, Rhodes J, Berman JN, Zon LI, Kanki JP, Look AT. The pu.1 promoter drives myeloid gene expression in zebrafish. Blood. 104: 1291-7. PMID 14996705 DOI: 10.1182/blood-2003-09-3105  0.56
2003 Traver D, Herbomel P, Patton EE, Murphey RD, Yoder JA, Litman GW, Catic A, Amemiya CT, Zon LI, Trede NS. The zebrafish as a model organism to study development of the immune system. Advances in Immunology. 81: 253-330. PMID 14711058  1
2003 Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature Immunology. 4: 1238-46. PMID 14608381 DOI: 10.1038/ni1007  1
2003 Piotrowski T, Ahn DG, Schilling TF, Nair S, Ruvinsky I, Geisler R, Rauch GJ, Haffter P, Zon LI, Zhou Y, Foott H, Dawid IB, Ho RK. The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development (Cambridge, England). 130: 5043-52. PMID 12952905 DOI: 10.1242/dev.00704  1
2003 Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, ... ... Zon LI, et al. Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature Genetics. 34: 59-64. PMID 12669066 DOI: 10.1038/ng1137  1
2003 Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT. Myc-induced T cell leukemia in transgenic zebrafish. Science (New York, N.Y.). 299: 887-90. PMID 12574629 DOI: 10.1126/science.1080280  0.56
2003 Davidson AJ, Zon LI. Biomedicine. Love, honor, and protect (your liver). Science (New York, N.Y.). 299: 835-7. PMID 12574609 DOI: 10.1126/science.1082006  1
2003 Galloway JL, Zon LI. Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Current Topics in Developmental Biology. 53: 139-58. PMID 12510667  0.88
2002 Burns CE, Zon LI. Portrait of a stem cell. Developmental Cell. 3: 612-3. PMID 12431368 DOI: 10.1016/S1534-5807(02)00329-5  1
2002 Best JL, Ganiatsas S, Agarwal S, Changou A, Salomoni P, Shirihai O, Meluh PB, Pandolfi PP, Zon LI. SUMO-1 protease-1 regulates gene transcription through PML. Molecular Cell. 10: 843-55. PMID 12419228 DOI: 10.1016/S1097-2765(02)00699-8  1
2002 Ross S, Best JL, Zon LI, Gill G. SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Molecular Cell. 10: 831-42. PMID 12419227 DOI: 10.1016/S1097-2765(02)00682-2  1
2002 Donovan A, Brownlie A, Dorschner MO, Zhou Y, Pratt SJ, Paw BH, Phillips RB, Thisse C, Thisse B, Zon LI. The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood. 100: 4655-9. PMID 12393445 DOI: 10.1182/blood-2002-04-1169  1
2002 Pratt SJ, Drejer A, Foott H, Barut B, Brownlie A, Postlethwait J, Kato Y, Yamamoto M, Zon LI. Isolation and characterization of zebrafish NFE2. Physiological Genomics. 11: 91-8. PMID 12388799 DOI: 10.1152/physiolgenomics.00112.2001  1
2002 Murphey RD, Zon LI. Attack of the fish clones. Nature Biotechnology. 20: 785-6. PMID 12148002 DOI: 10.1038/nbt0802-785  0.92
2002 Amatruda JF, Shepard JL, Stern HM, Zon LI. Zebrafish as a cancer model system. Cancer Cell. 1: 229-31. PMID 12086858  1
2002 Lieschke GJ, Oates AC, Paw BH, Thompson MA, Hall NE, Ward AC, Ho RK, Zon LI, Layton JE. Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Developmental Biology. 246: 274-95. PMID 12051816 DOI: 10.1006/dbio.2002.0657  1
2002 Liu TX, Zhou Y, Kanki JP, Deng M, Rhodes J, Yang HW, Sheng XM, Zon LI, Look AT. Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies. Proceedings of the National Academy of Sciences of the United States of America. 99: 6136-41. PMID 11983906 DOI: 10.1073/pnas.072560099  0.48
2002 Traver D, Zon LI. Walking the walk: migration and other common themes in blood and vascular development. Cell. 108: 731-4. PMID 11955426 DOI: 10.1016/S0092-8674(02)00686-4  0.56
2002 Orkin SH, Zon LI. Hematopoiesis and stem cells: Plasticity versus development heterogeneity Nature Immunology. 3: 323-328. PMID 11919568 DOI: 10.1038/ni0402-323  1
2001 Lyons SE, Shue BC, Lei L, Oates AC, Zon LI, Liu PP. Molecular cloning, genetic mapping, and expression analysis of four zebrafish c/ebp genes. Gene. 281: 43-51. PMID 11750126 DOI: 10.1016/S0378-1119(01)00774-0  1
2001 Hukriede N, Fisher D, Epstein J, Joly L, Tellis P, Zhou Y, Barbazuk B, Cox K, Fenton-Noriega L, Hersey C, Miles J, Sheng X, Song A, Waterman R, Johnson SL, ... ... Zon LI, et al. The LN54 radiation hybrid map of zebrafish expressed sequences. Genome Research. 11: 2127-32. PMID 11731504 DOI: 10.1101/gr.210601  1
2001 Huber TL, Perkins AC, Deconinck AE, Chan FY, Mead PE, Zon LI. neptune, a Krüppel-like transcription factor that participates in primitive erythropoiesis in Xenopus. Current Biology : Cb. 11: 1456-61. PMID 11566106 DOI: 10.1016/S0960-9822(01)00427-4  1
2001 Oates AC, Pratt SJ, Vail B, Yan Yl, Ho RK, Johnson SL, Postlethwait JH, Zon LI. The zebrafish klf gene family. Blood. 98: 1792-801. PMID 11535513 DOI: 10.1182/blood.V98.6.1792  1
2001 Mead PE, Deconinck AE, Huber TL, Orkin SH, Zon LI. Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins. Development (Cambridge, England). 128: 2301-8. PMID 11493549  1
2001 Bennett CM, Kanki JP, Rhodes J, Liu TX, Paw BH, Kieran MW, Langenau DM, Delahaye-Brown A, Zon LI, Fleming MD, Look AT. Myelopoiesis in the zebrafish, Danio rerio. Blood. 98: 643-51. PMID 11468162 DOI: 10.1182/blood.V98.3.643  1
2001 Lyons SE, Shue BC, Oates AC, Zon LI, Liu PP. A novel myeloid-restricted zebrafish CCAAT/enhancer-binding protein with a potent transcriptional activation domain. Blood. 97: 2611-7. PMID 11313249 DOI: 10.1182/blood.V97.9.2611  1
2000 Davidson AJ, Zon LI. Turning mesoderm into blood: the formation of hematopoietic stem cells during embryogenesis. Current Topics in Developmental Biology. 50: 45-60. PMID 10948449 DOI: 10.1016/S0070-2153(00)50003-9  1
2000 Dooley K, Zon LI. Zebrafish: A model system for the study of human disease Current Opinion in Genetics and Development. 10: 252-256. PMID 10826982 DOI: 10.1016/S0959-437X(00)00074-5  1
2000 Deconinck AE, Mead PE, Tevosian SG, Crispino JD, Katz SG, Zon LI, Orkin SH. FOG acts as a repressor of red blood cell development in Xenopus Development. 127: 2031-2040. PMID 10769228  1
2000 Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, ... ... Zon LI, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 403: 776-81. PMID 10693807 DOI: 10.1038/35001596  0.48
2000 Shepard JL, Zon LI. Developmental derivation of embryonic and adult macrophages. Current Opinion in Hematology. 7: 3-8. PMID 10608497  1
1999 Kieran MW, Katz S, Vail B, Zon LI, Mayer BJ. Concentration-dependent positive and negative regulation of a MAP kinase by a MAP kinase kinase. Oncogene. 18: 6647-57. PMID 10597270 DOI: 10.1038/sj.onc.1203057  1
1999 Porcher C, Liao EC, Fujiwara Y, Zon LI, Orkin SH. Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding. Development (Cambridge, England). 126: 4603-15. PMID 10498694  1
1999 Hukriede NA, Joly L, Tsang M, Miles J, Tellis P, Epstein JA, Barbazuk WB, Li FN, Paw B, Postlethwait JH, Hudson TJ, Zon LI, McPherson JD, Chevrette M, Dawid IB, et al. Radiation hybrid mapping of the zebrafish genome. Proceedings of the National Academy of Sciences of the United States of America. 96: 9745-50. PMID 10449765 DOI: 10.1073/pnas.96.17.9745  1
1999 Rubin DA, Hellman P, Zon LI, Lobb CJ, Bergwitz C, Jüppner H. A G protein-coupled receptor from zebrafish is activated by human parathyroid hormone and not by human or teleost parathyroid hormone-related peptide. Implications for the evolutionary conservation of calcium-regulating peptide hormones Journal of Biological Chemistry. 274: 23035-23042. PMID 10438471 DOI: 10.1074/jbc.274.33.23035  1
1999 Oates AC, Wollberg P, Pratt SJ, Paw BH, Johnson SL, Ho RK, Postlethwait JH, Zon LI, Wilks AF. Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 215: 352-70. PMID 10417824 DOI: 10.1002/(SICI)1097-0177(199908)215:4<352::AID-AJA7>3.0.CO;2-J  1
1999 Meriin AB, Yaglom JA, Gabai VL, Mosser DD, Zon L, Sherman MY. Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: A novel pathway controlled by HSP72 Molecular and Cellular Biology. 19: 2547-2555. PMID 10082520 DOI: 10.1128/MCB.19.4.2547  1
1999 Parker LH, Zon LI, Stainier DYR. Vascular and blood gene expression Methods in Cell Biology. 313-336. PMID 9891367 DOI: 10.1016/S0091-679X(08)61832-4  1
1999 Detrich HW, Westerfield M, Zon LI. Overview of the Zebrafish system. Methods in Cell Biology. 59: 3-10. PMID 9891351 DOI: 10.1016/S0091-679X(08)61816-6  1
1999 Johnson SL, Zon LI. Genetic backgrounds and some standard stocks and strains used in zebrafish developmental biology and genetics Methods in Cell Biology. 60: 357-359. PMID 9891347 DOI: 10.1016/S0091-679X(08)61910-X  1
1999 Amemiya CT, Zhong TP, Silverman GA, Fishman MC, Zon LI. Zebrafish YAC, BAC, and PAC genomic libraries. Methods in Cell Biology. 60: 235-58. PMID 9891341 DOI: 10.1016/S0091-679X(08)61904-4  1
1999 Liao EC, Zon LI. Simple sequence-length polymorphism analysis Methods in Cell Biology. 181-183. PMID 9891337 DOI: 10.1016/S0091-679X(08)61900-7  1
1998 Brownlie A, Donovan A, Pratt SJ, Paw BH, Oates AC, Brugnara C, Witkowska HE, Sassa S, Zon LI. Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nature Genetics. 20: 244-50. PMID 9806542 DOI: 10.1038/3049  1
1998 Lee KH, Marden JJ, Thompson MS, Maclennan H, Kishimoto Y, Pratt SJ, Schulte-Merker S, Hammerschmidt M, Johnson SL, Postlethwaite JH, Beier DC, Zon LI. Cloning and genetic mapping of zebrafish BMP-2 Developmental Genetics. 23: 97-103. PMID 9770266 DOI: 10.1002/(SICI)1520-6408(1998)23:2<97::AID-DVG1>3.0.CO;2-0  1
1998 Mead PE, Zhou Y, Lustig KD, Huber TL, Kirschner MW, Zon LI. Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 95: 11251-6. PMID 9736722 DOI: 10.1073/pnas.95.19.11251  1
1998 Alberola-lla J, Levin SD, Barton G, Forbush K, Zon LI, Perlmutter RM. Analysis of the pole of MKK-4/Sek-1 in T cell development and apoptosis International Immunology. 10: 1077-1082. PMID 9723693 DOI: 10.1093/intimm/10.8.1077  1
1998 Thompson MA, Ransom DG, Pratt SJ, MacLennan H, Kieran MW, Detrich HW, Vail B, Huber TL, Paw B, Brownlie AJ, Oates AC, Fritz A, Gates MA, Amores A, Bahary N, ... ... Zon LI, et al. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Developmental Biology. 197: 248-69. PMID 9630750 DOI: 10.1006/dbio.1998.8887  1
1998 Huber TL, Zon LI. Transcriptional regulation of blood formation during Xenopus development. Seminars in Immunology. 10: 103-9. PMID 9618755 DOI: 10.1006/smim.1998.0111  1
1998 Jessen JR, Meng A, McFarlane RJ, Paw BH, Zon LI, Smith GR, Lin S. Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 5121-6. PMID 9560239 DOI: 10.1073/pnas.95.9.5121  0.44
1998 Postlethwait JH, Yan YL, Gates MA, Horne S, Amores A, Brownlie A, Donovan A, Egan ES, Force A, Gong Z, Goutel C, Fritz A, Kelsh R, Knapik E, Liao E, ... ... Zon LI, et al. Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18: 345-9. PMID 9537416 DOI: 10.1038/ng0498-345  1
1998 Liao EC, Paw BH, Oates AC, Pratt SJ, Postlethwait JH, Zon LI. SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes & Development. 12: 621-6. PMID 9499398 DOI: 10.1101/gad.12.5.621  1
1997 Orkin SH, Zon LI. Genetics of erythropoiesis: Induced mutations in mice and zebrafish Annual Review of Genetics. 31: 33-60. PMID 9442889 DOI: 10.1146/annurev.genet.31.1.33  1
1997 Turpen JB, Kelley CM, Mead PE, Zon LI. Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo. Immunity. 7: 325-34. PMID 9324353 DOI: 10.1016/S1074-7613(00)80354-4  1
1997 Lustig KD, Stukenberg PT, McGarry TJ, King RW, Cryns VL, Mead PE, Zon LI, Yuan J, Kirschner MW. Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development. Methods in Enzymology. 283: 83-99. PMID 9251013 DOI: 10.1016/S0076-6879(97)83009-1  1
1997 Hirai SI, Katoh M, Terada M, Kyriakis JM, Zon LI, Rana A, Avruch J, Ohno S. MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase Journal of Biological Chemistry. 272: 15167-15173. PMID 9182538 DOI: 10.1074/jbc.272.24.15167  1
1997 Molnár A, Theodoras AM, Zon LI, Kyriakis JM. Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK. The Journal of Biological Chemistry. 272: 13229-35. PMID 9148940 DOI: 10.1074/jbc.272.20.13229  1
1997 Chan FY, Robinson J, Brownlie A, Shivdasani RA, Donovan A, Brugnara C, Kim J, Lau BC, Witkowska HE, Zon LI. Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 89: 688-700. PMID 9002973  0.44
1996 Kieran MW, Perkins AC, Orkin SH, Zon LI. Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. Proceedings of the National Academy of Sciences of the United States of America. 93: 9126-31. PMID 8799165  1
1996 Rana A, Gallo K, Godowski P, Hirai SI, Ohno S, Zon L, Kyriakis JM, Avruch J. The mixed lineage kinase SPRK phosphorylates and activates the stress- activated protein kinase activator, SEK-1 Journal of Biological Chemistry. 271: 19025-19028. PMID 8702571 DOI: 10.1074/jbc.271.32.19025  1
1996 Mead PE, Brivanlou IH, Kelley CM, Zon LI. BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.1. Nature. 382: 357-60. PMID 8684465 DOI: 10.1038/382357a0  1
1996 Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. The Journal of Biological Chemistry. 271: 3229-37. PMID 8621725 DOI: 10.1074/jbc.271.6.3229  1
1996 Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S, Birrer MJ, Szabo E, Zon LI, Kyriakis JM, Haimovitz-Friedman A, Fuks Z, Kolesnick RN. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis Nature. 380: 75-79. PMID 8598911 DOI: 10.1038/380075a0  1
1995 Hughes R, Chan FY, White RA, Zon LI. Cloning and chromosomal localization of a mouse cDNA with homology to the Saccharomyces cerevisiae gene zuotin. Genomics. 29: 546-50. PMID 8666407 DOI: 10.1006/geno.1995.9969  0.44
1995 Detrich HW, Kieran MW, Chan FY, Barone LM, Yee K, Rundstadler JA, Pratt S, Ransom D, Zon LI. Intraembryonic hematopoietic cell migration during vertebrate development. Proceedings of the National Academy of Sciences of the United States of America. 92: 10713-7. PMID 7479870 DOI: 10.1073/pnas.92.23.10713  1
1995 Pombo CM, Kehrl JH, Sánchez I, Katz P, Avruch J, Zon LI, Woodgett JR, Force T, Kyriakis JM. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase Nature. 377: 750-754. PMID 7477268  1
1994 Kelley C, Yee K, Harland R, Zon LI. Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm. Developmental Biology. 165: 193-205. PMID 8088437 DOI: 10.1006/dbio.1994.1246  1
1994 Yan M, Dai T, Deak JC, Kyriakis JM, Zon LI, Woodgett JR, Templeton DJ. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 Nature. 372: 798-800. PMID 7997270  1
1994 Sánchez I, Hughes RT, Mayer BJ, Yee K, Woodgett JR, Avruch J, Kyriakis JM, Zon LI. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature. 372: 794-8. PMID 7997269  1
1993 Zon LI, Yamaguchi Y, Yee K, Albee EA, Kimura A, Bennett JC, Orkin SH, Ackerman SJ. Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. Blood. 81: 3234-41. PMID 8507862  1
1993 Yashar BM, Kelley C, Yee K, Errede B, Zon LI. Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis Molecular and Cellular Biology. 13: 5738-5748. PMID 8395011 DOI: 10.1128/MCB.13.9.5738  1
1992 Sposi NM, Zon LI, Carè A, Valtieri M, Testa U, Gabbianelli M, Mariani G, Bottero L, Mather C, Orkin SH. Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors. Proceedings of the National Academy of Sciences of the United States of America. 89: 6353-7. PMID 1631130  1
1992 Zon LI, Orkin SH. Sequence of the human GATA-1 promoter Nucleic Acids Research. 20: 1812. PMID 1579480 DOI: 10.1093/nar/20.7.1812  1
1992 Barut BA, Zon LI, Cochran MK, Paul SR, Chauhan D, Mohrbacher A, Fingeroth J, Anderson KC. Role of interleukin 6 in the growth of myeloma-derived cell lines. Leukemia Research. 16: 951-9. PMID 1405708 DOI: 10.1016/0145-2126(92)90073-G  1
1992 Zon LI, Moreau JF, Koo JW, Mathey-Prevot B, D'Andrea AD. The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein. Molecular and Cellular Biology. 12: 2949-57. PMID 1320192 DOI: 10.1128/MCB.12.7.2949  1
1991 Zon LI, Mather C, Burgess S, Bolce ME, Harland RM, Orkin SH. Expression of GATA-binding proteins during embryonic development in Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America. 88: 10642-6. PMID 1961730  1
1991 D'Andrea AD, Yoshimura A, Youssoufian H, Zon LI, Koo JW, Lodish HF. The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Molecular and Cellular Biology. 11: 1980-7. PMID 1848667 DOI: 10.1128/MCB.11.4.1980  1
1991 Zon LI, Gurish MF, Stevens RL, Mather C, Reynolds DS, Austen KF, Orkin SH. GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene. The Journal of Biological Chemistry. 266: 22948-53. PMID 1744088  1
1991 Zon LI, Youssoufian H, Mather C, Lodish HF, Orkin SH. Activation of the erythropoietin receptor promoter by transcription factor GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 88: 10638-41. PMID 1660143  1
1990 Martin DI, Zon LI, Mutter G, Orkin SH. Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. Nature. 344: 444-7. PMID 2320112 DOI: 10.1038/344444a0  1
1990 Zon LI, Tsai SF, Burgess S, Matsudaira P, Bruns GAP, Orkin SH. The major human erythroid DNA-binding protein (GF-1): Primary sequence and localization of the gene to the X chromosome Proceedings of the National Academy of Sciences of the United States of America. 87: 668-672. PMID 2300555  1
1990 Youssoufian H, Zon LI, Orkin SH, D'Andrea AD, Lodish HF. Structure and transcription of the mouse erythropoietin receptor gene. Molecular and Cellular Biology. 10: 3675-82. PMID 2162479 DOI: 10.1128/MCB.10.7.3675  1
1989 Tsai SF, Martin DI, Zon LI, D'Andrea AD, Wong GG, Orkin SH. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature. 339: 446-51. PMID 2725678 DOI: 10.1038/339446a0  1
1989 Zon LI, Dorfman DM, Orkin SH. The polymerase chain reaction colony miniprep Biotechniques. 7: 696-698. PMID 2631784  1
1989 Dorfman DM, Zon LI, Orkin SH. Rapid amplification of lambda gt11 bacteriophage library inserts from plaques using the polymerase chain reaction (PCR) Biotechniques. 7. PMID 2534350  1
1987 Donahue RE, Johnson MM, Zon LI, Clark SC, Groopman JE. Suppression of in vitro haematopoiesis following human immunodeficiency virus infection Nature. 326: 200-203. PMID 2434864 DOI: 10.1038/326200a0  1
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