Joshua Mendell - Publications

Human Genetics Johns Hopkins University, Baltimore, MD 
Genetics, Molecular Biology

42/64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Quirin KA, Kwon JJ, Alioufi A, Factora T, Temm CJ, Jacobsen M, Sandusky GE, Shontz K, Chicoine LG, Clark KR, Mendell JT, Korc M, Kota J. Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice. Molecular Therapy. Methods & Clinical Development. 8: 8-20. PMID 29349096 DOI: 10.1016/j.omtm.2017.09.006  0.32
2016 Kent OA, Mendell JT, Rottapel R. Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1. Molecular Cancer Research : McR. 14: 267-77. PMID 26747707 DOI: 10.1158/1541-7786.MCR-15-0456  0.84
2015 Wu L, Nguyen LH, Zhou K, de Soysa TY, Li L, Miller JB, Tian J, Locker J, Zhang S, Shinoda G, Seligson MT, Zeitels LR, Acharya A, Wang SC, Mendell JT, et al. Precise let-7 expression levels balance organ regeneration against tumor suppression. Elife. 4. PMID 26445246 DOI: 10.7554/eLife.09431  0.84
2015 Chang TC, Pertea M, Lee S, Salzberg SL, Mendell JT. Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms. Genome Research. 25: 1401-9. PMID 26290535 DOI: 10.1101/gr.193607.115  0.84
2015 Knabel MK, Ramachandran K, Karhadkar S, Hwang HW, Creamer TJ, Chivukula RR, Sheikh F, Clark KR, Torbenson M, Montgomery RA, Cameron AM, Mendell JT, Warren DS. Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice. Plos One. 10: e0124411. PMID 25923107 DOI: 10.1371/journal.pone.0124411  0.84
2015 Pertea M, Pertea GM, Antonescu CM, Chang TC, Mendell JT, Salzberg SL. StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nature Biotechnology. 33: 290-5. PMID 25690850 DOI: 10.1038/nbt.3122  0.84
2015 Huang TC, Renuse S, Pinto S, Kumar P, Yang Y, Chaerkady R, Godsey B, Mendell JT, Halushka MK, Civin CI, Marchionni L, Pandey A. Identification of miR-145 targets through an integrated omics analysis. Molecular Biosystems. 11: 197-207. PMID 25354783 DOI: 10.1039/c4mb00585f  0.84
2014 Shi G, Mendell JT. Seeing through the miRage of tissue complexity. Cell Cycle (Georgetown, Tex.). 13: 2988-9. PMID 25486556 DOI: 10.4161/15384101.2014.962852  0.84
2014 Zeitels LR, Acharya A, Shi G, Chivukula D, Chivukula RR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Richardson JA, Mendell JT. Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis. Genes & Development. 28: 2585-90. PMID 25395662 DOI: 10.1101/gad.250951.114  0.84
2014 Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nature Communications. 2: 4802. PMID 25190313 DOI: 10.1038/ncomms5802  0.84
2014 Chivukula RR, Shi G, Acharya A, Mills EW, Zeitels LR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Maitra A, Mendell JT. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 157: 1104-16. PMID 24855947 DOI: 10.1016/j.cell.2014.03.055  0.84
2013 Lieberman J, Slack F, Pandolfi PP, Chinnaiyan A, Agami R, Mendell JT. Noncoding RNAs and cancer. Cell. 153: 9-10. PMID 23781554 DOI: 10.1016/j.cell.2013.03.019  0.84
2012 Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, ... ... Mendell JT, et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. The Journal of Clinical Investigation. 122: 2871-83. PMID 22820288 DOI: 10.1172/JCI63539  0.84
2012 Ribas J, Ni X, Castanares M, Liu MM, Esopi D, Yegnasubramanian S, Rodriguez R, Mendell JT, Lupold SE. A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts. Nucleic Acids Research. 40: 6821-33. PMID 22505577 DOI: 10.1093/nar/gks308  0.84
2012 Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell. 148: 1172-87. PMID 22424228 DOI: 10.1016/j.cell.2012.02.005  0.84
2011 Chaulk SG, Thede GL, Kent OA, Xu Z, Gesner EM, Veldhoen RA, Khanna SK, Goping IS, MacMillan AM, Mendell JT, Young HS, Fahlman RP, Glover JN. Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis. Rna Biology. 8: 1105-14. PMID 21955497 DOI: 10.4161/rna.8.6.17410  0.84
2011 Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM. KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood. 117: 3629-40. PMID 21273305 DOI: 10.1182/blood-2010-07-293548  0.84
2010 Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, Mendell JT. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes & Development. 24: 2754-9. PMID 21159816 DOI: 10.1101/gad.1950610  0.68
2010 Persat A, Chivukula RR, Mendell JT, Santiago JG. Quantification of global microRNA abundance by selective isotachophoresis. Analytical Chemistry. 82: 9631-5. PMID 21062022 DOI: 10.1021/ac102496m  0.84
2010 Bui TV, Mendell JT. Myc: Maestro of MicroRNAs. Genes & Cancer. 1: 568-575. PMID 20882107 DOI: 10.1177/1947601910377491  0.84
2010 Yamakuchi M, Lotterman CD, Bao C, Hruban RH, Karim B, Mendell JT, Huso D, Lowenstein CJ. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6334-9. PMID 20308559 DOI: 10.1073/pnas.0911082107  0.84
2009 Kent OA, Mullendore M, Wentzel EA, López-Romero P, Tan AC, Alvarez H, West K, Ochs MF, Hidalgo M, Arking DE, Maitra A, Mendell JT. A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. Cancer Biology & Therapy. 8: 2013-24. PMID 20037478  0.68
2009 Ribas J, Ni X, Haffner M, Wentzel EA, Salmasi AH, Chowdhury WH, Kudrolli TA, Yegnasubramanian S, Luo J, Rodriguez R, Mendell JT, Lupold SE. miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth. Cancer Research. 69: 7165-9. PMID 19738047 DOI: 10.1158/0008-5472.CAN-09-1448  0.84
2009 Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 137: 1005-17. PMID 19524505 DOI: 10.1016/j.cell.2009.04.021  0.84
2009 Chivukula RR, Mendell JT. Abate and switch: miR-145 in stem cell differentiation. Cell. 137: 606-8. PMID 19450510 DOI: 10.1016/j.cell.2009.04.059  0.64
2009 Hwang HW, Wentzel EA, Mendell JT. Cell-cell contact globally activates microRNA biogenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 7016-21. PMID 19359480 DOI: 10.1073/pnas.0811523106  0.84
2009 Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV. C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism Nature. 458: 762-765. PMID 19219026 DOI: 10.1038/nature07823  0.84
2008 Yu X, Lin J, Zack DJ, Mendell JT, Qian J. Analysis of regulatory network topology reveals functionally distinct classes of microRNAs. Nucleic Acids Research. 36: 6494-503. PMID 18927108 DOI: 10.1093/nar/gkn712  0.84
2008 Chivukula RR, Mendell JT. Circular reasoning: microRNAs and cell-cycle control. Trends in Biochemical Sciences. 33: 474-81. PMID 18774719 DOI: 10.1016/j.tibs.2008.06.008  0.64
2008 Chung EY, Dews M, Cozma D, Yu D, Wentzel EA, Chang TC, Schelter JM, Cleary MA, Mendell JT, Thomas-Tikhonenko A. c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster. Cancer Biology & Therapy. 7: 1758-64. PMID 18708755  0.84
2008 Harris TA, Yamakuchi M, Ferlito M, Mendell JT, Lowenstein CJ. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proceedings of the National Academy of Sciences of the United States of America. 105: 1516-21. PMID 18227515 DOI: 10.1073/pnas.0707493105  0.84
2008 Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM, Dang CV, Thomas-Tikhonenko A, Mendell JT. Widespread microRNA repression by Myc contributes to tumorigenesis Nature Genetics. 40: 43-50. PMID 18066065 DOI: 10.1038/ng.2007.30  0.84
2007 Bruchova H, Yoon D, Agarwal AM, Mendell J, Prchal JT. Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Experimental Hematology. 35: 1657-67. PMID 17976518 DOI: 10.1016/j.exphem.2007.08.021  0.84
2007 Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Molecular Cell. 26: 745-52. PMID 17540599 DOI: 10.1016/j.molcel.2007.05.010  0.84
2007 Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. British Journal of Cancer. 96: R40-4. PMID 17393584  0.84
2007 Hwang HW, Wentzel EA, Mendell JT. A hexanucleotide element directs microRNA nuclear import. Science (New York, N.Y.). 315: 97-100. PMID 17204650 DOI: 10.1126/science.1136235  0.84
2006 Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, Furth EE, Lee WM, Enders GH, Mendell JT, Thomas-Tikhonenko A. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nature Genetics. 38: 1060-5. PMID 16878133 DOI: 10.1038/ng1855  0.84
2006 Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT, Jiang J, Schmittgen TD, Patel T. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology. 130: 2113-29. PMID 16762633 DOI: 10.1053/j.gastro.2006.02.057  0.84
2006 Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. British Journal of Cancer. 94: 776-80. PMID 16495913 DOI: 10.1038/sj.bjc.6603023  0.84
2005 O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature. 435: 839-43. PMID 15944709 DOI: 10.1038/nature03677  0.84
2004 Mendell JT, Sharifi NA, Meyers JL, Martinez-Murillo F, Dietz HC. Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise. Nature Genetics. 36: 1073-8. PMID 15448691 DOI: 10.1038/ng1429  0.56
2002 Mendell JT, ap Rhys CM, Dietz HC. Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts. Science (New York, N.Y.). 298: 419-22. PMID 12228722 DOI: 10.1126/science.1074428  0.56
Low-probability matches
2011 Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Molecular Cancer Therapeutics. 10: 1470-80. PMID 21622730 DOI: 10.1158/1535-7163.MCT-11-0152  0.24
2010 Yang Y, Chaerkady R, Kandasamy K, Huang TC, Selvan LD, Dwivedi SB, Kent OA, Mendell JT, Pandey A. Identifying targets of miR-143 using a SILAC-based proteomic approach. Molecular Biosystems. 6: 1873-82. PMID 20544124 DOI: 10.1039/c004401f  0.24
2009 Lee KH, Lotterman C, Karikari C, Omura N, Feldmann G, Habbe N, Goggins MG, Mendell JT, Maitra A. Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 9: 293-301. PMID 19407485 DOI: 10.1159/000186051  0.24
2009 Habbe N, Koorstra JB, Mendell JT, Offerhaus GJ, Ryu JK, Feldmann G, Mullendore ME, Goggins MG, Hong SM, Maitra A. MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biology & Therapy. 8: 340-6. PMID 19106647  0.24
2008 Lotterman CD, Kent OA, Mendell JT. Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle (Georgetown, Tex.). 7: 2493-9. PMID 18719378 DOI: 10.4161/cc.7.16.6452  0.24
2018 Hunter RW, Liu Y, Manjunath H, Acharya A, Jones BT, Zhang H, Chen B, Ramalingam H, Hammer RE, Xie Y, Richardson JA, Rakheja D, Carroll TJ, Mendell JT. Loss of partially phenocopies Perlman syndrome in mice and results in up-regulation of in nephron progenitor cells. Genes & Development. PMID 29950491 DOI: 10.1101/gad.315804.118  0.12
2013 Zeitels LR, Mendell JT. When 19 is greater than 92. Elife. 2: e01514. PMID 24137549 DOI: 10.7554/eLife.01514  0.08
2009 Yang Y, Chaerkady R, Beer MA, Mendell JT, Pandey A. Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics. 9: 1374-84. PMID 19253296 DOI: 10.1002/pmic.200800551  0.04
2019 Kopp F, Elguindy MM, Yalvac ME, Zhang H, Chen B, Gillett FA, Lee S, Sivakumar S, Yu H, Xie Y, Mishra P, Sahenk Z, Mendell JT. PUMILIO hyperactivity drives premature aging of -deficient mice. Elife. 8. PMID 30735131 DOI: 10.7554/eLife.42650  0.01
2018 Chen KS, Stroup EK, Budhipramono A, Rakheja D, Nichols-Vinueza D, Xu L, Stuart SH, Shukla AA, Fraire C, Mendell JT, Amatruda JF. Mutations in microRNA processing genes in Wilms tumors derepress the regulator . Genes & Development. PMID 30026293 DOI: 10.1101/gad.313783.118  0.01
2018 Chang TC, Mendell JT. High-Throughput Characterization of Primary microRNA Transcripts. Methods in Molecular Biology (Clifton, N.J.). 1823: 1-9. PMID 29959669 DOI: 10.1007/978-1-4939-8624-8_1  0.01
2018 Kopp F, Mendell JT. Functional Classification and Experimental Dissection of Long Noncoding RNAs. Cell. 172: 393-407. PMID 29373828 DOI: 10.1016/j.cell.2018.01.011  0.01
2017 Heller KN, Mendell JT, Mendell JR, Rodino-Klapac LR. MicroRNA-29 overexpression by adeno-associated virus suppresses fibrosis and restores muscle function in combination with micro-dystrophin. Jci Insight. 2. PMID 28469083 DOI: 10.1172/jci.insight.93309  0.01
2017 Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT. An Argonaute phosphorylation cycle promotes microRNA-mediated silencing. Nature. PMID 28114302 DOI: 10.1038/nature21025  0.01
2016 Mendell JT. Targeting a Long Noncoding RNA in Breast Cancer. The New England Journal of Medicine. 374: 2287-9. PMID 27276568 DOI: 10.1056/NEJMcibr1603785  0.01
2015 Lee S, Kopp F, Chang TC, Sataluri A, Chen B, Sivakumar S, Yu H, Xie Y, Mendell JT. Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins. Cell. PMID 26724866 DOI: 10.1016/j.cell.2015.12.017  0.01
2014 Krzeszinski JY, Wei W, Huynh H, Jin Z, Wang X, Chang TC, Xie XJ, He L, Mangala LS, Lopez-Berestein G, Sood AK, Mendell JT, Wan Y. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature. 512: 431-5. PMID 25043055 DOI: 10.1038/nature13375  0.01
2014 Chen B, Yun J, Kim MS, Mendell JT, Xie Y. PIPE-CLIP: a comprehensive online tool for CLIP-seq data analysis. Genome Biology. 15: R18. PMID 24451213 DOI: 10.1186/gb-2014-15-1-r18  0.01
2009 Mendell JT. Tumors line up for a letdown. Nature Genetics. 41: 768-9. PMID 19557079 DOI: 10.1038/ng0709-768  0.01
2008 Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell. 133: 217-22. PMID 18423194 DOI: 10.1016/j.cell.2008.04.001  0.01
2007 Chang TC, Mendell JT. microRNAs in vertebrate physiology and human disease. Annual Review of Genomics and Human Genetics. 8: 215-39. PMID 17506656 DOI: 10.1146/annurev.genom.8.080706.092351  0.01
2005 Mendell JT. MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle (Georgetown, Tex.). 4: 1179-84. PMID 16096373 DOI: 10.4161/cc.4.9.2032  0.01
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