Joshua Mendell - Publications

Affiliations: 
Human Genetics Johns Hopkins University, Baltimore, MD 
Area:
Genetics, Molecular Biology

67/112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jones BT, Han J, Zhang H, Hammer RE, Evers BM, Rakheja D, Acharya A, Mendell JT. Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Genes & Development. PMID 37553261 DOI: 10.1101/gad.350906.123  0.578
2023 Jones BT, Han J, Zhang H, Hammer RE, Evers BM, Rakheja D, Acharya A, Mendell JT. Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Biorxiv : the Preprint Server For Biology. PMID 37425885 DOI: 10.1101/2023.06.26.546601  0.578
2022 Han J, Mendell JT. MicroRNA turnover: a tale of tailing, trimming, and targets. Trends in Biochemical Sciences. PMID 35811249 DOI: 10.1016/j.tibs.2022.06.005  0.518
2020 Han J, LaVigne CA, Jones BT, Zhang H, Gillett F, Mendell JT. A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming. Science (New York, N.Y.). PMID 33184234 DOI: 10.1126/science.abc9546  0.523
2019 Acharya A, Berry DC, Zhang H, Jiang Y, Jones BT, Hammer RE, Graff JM, Mendell JT. miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting . Genes & Development. PMID 31488578 DOI: 10.1101/Gad.328955.119  0.428
2019 Du Q, Hoover AR, Dozmorov I, Raj P, Khan S, Molina E, Chang TC, de la Morena MT, Cleaver OB, Mendell JT, van Oers NSC. MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary. Developmental Cell. PMID 30982661 DOI: 10.1016/J.Devcel.2019.03.012  0.52
2018 Chang TC, Mendell JT. High-Throughput Characterization of Primary microRNA Transcripts. Methods in Molecular Biology (Clifton, N.J.). 1823: 1-9. PMID 29959669 DOI: 10.1007/978-1-4939-8624-8_1  0.507
2017 Heller KN, Mendell JT, Mendell JR, Rodino-Klapac LR. MicroRNA-29 overexpression by adeno-associated virus suppresses fibrosis and restores muscle function in combination with micro-dystrophin. Jci Insight. 2. PMID 28469083 DOI: 10.1172/Jci.Insight.93309  0.346
2017 Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT. An Argonaute phosphorylation cycle promotes microRNA-mediated silencing. Nature. PMID 28114302 DOI: 10.1038/Nature21025  0.504
2016 Kent OA, Mendell JT, Rottapel R. Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1. Molecular Cancer Research : McR. 14: 267-77. PMID 26747707 DOI: 10.1158/1541-7786.Mcr-15-0456  0.528
2015 Chang TC, Pertea M, Lee S, Salzberg SL, Mendell JT. Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms. Genome Research. 25: 1401-9. PMID 26290535 DOI: 10.1101/Gr.193607.115  0.514
2015 Knabel MK, Ramachandran K, Karhadkar S, Hwang HW, Creamer TJ, Chivukula RR, Sheikh F, Clark KR, Torbenson M, Montgomery RA, Cameron AM, Mendell JT, Warren DS. Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice. Plos One. 10: e0124411. PMID 25923107 DOI: 10.1371/Journal.Pone.0124411  0.793
2015 Huang TC, Renuse S, Pinto S, Kumar P, Yang Y, Chaerkady R, Godsey B, Mendell JT, Halushka MK, Civin CI, Marchionni L, Pandey A. Identification of miR-145 targets through an integrated omics analysis. Molecular Biosystems. 11: 197-207. PMID 25354783 DOI: 10.1039/C4Mb00585F  0.59
2014 Shi G, Mendell JT. Seeing through the miRage of tissue complexity. Cell Cycle (Georgetown, Tex.). 13: 2988-9. PMID 25486556 DOI: 10.4161/15384101.2014.962852  0.541
2014 Zeitels LR, Acharya A, Shi G, Chivukula D, Chivukula RR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Richardson JA, Mendell JT. Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis. Genes & Development. 28: 2585-90. PMID 25395662 DOI: 10.1101/Gad.250951.114  0.749
2014 Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nature Communications. 2: 4802. PMID 25190313 DOI: 10.1038/Ncomms5802  0.464
2014 Krzeszinski JY, Wei W, Huynh H, Jin Z, Wang X, Chang TC, Xie XJ, He L, Mangala LS, Lopez-Berestein G, Sood AK, Mendell JT, Wan Y. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature. 512: 431-5. PMID 25043055 DOI: 10.1038/Nature13375  0.323
2014 Chivukula RR, Shi G, Acharya A, Mills EW, Zeitels LR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Maitra A, Mendell JT. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 157: 1104-16. PMID 24855947 DOI: 10.1016/J.Cell.2014.03.055  0.799
2013 Zeitels LR, Mendell JT. When 19 is greater than 92. Elife. 2: e01514. PMID 24137549 DOI: 10.7554/eLife.01514  0.416
2012 Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, ... ... Mendell JT, et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. The Journal of Clinical Investigation. 122: 2871-83. PMID 22820288 DOI: 10.1172/Jci63539  0.766
2012 Ribas J, Ni X, Castanares M, Liu MM, Esopi D, Yegnasubramanian S, Rodriguez R, Mendell JT, Lupold SE. A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts. Nucleic Acids Research. 40: 6821-33. PMID 22505577 DOI: 10.1093/Nar/Gks308  0.485
2012 Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell. 148: 1172-87. PMID 22424228 DOI: 10.1016/J.Cell.2012.02.005  0.483
2011 Chaulk SG, Thede GL, Kent OA, Xu Z, Gesner EM, Veldhoen RA, Khanna SK, Goping IS, MacMillan AM, Mendell JT, Young HS, Fahlman RP, Glover JN. Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis. Rna Biology. 8: 1105-14. PMID 21955497 DOI: 10.4161/Rna.8.6.17410  0.585
2011 Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Molecular Cancer Therapeutics. 10: 1470-80. PMID 21622730 DOI: 10.1158/1535-7163.Mct-11-0152  0.805
2011 Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM. KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood. 117: 3629-40. PMID 21273305 DOI: 10.1182/blood-2010-07-293548  0.549
2010 Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, Mendell JT. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes & Development. 24: 2754-9. PMID 21159816 DOI: 10.1101/Gad.1950610  0.772
2010 Persat A, Chivukula RR, Mendell JT, Santiago JG. Quantification of global microRNA abundance by selective isotachophoresis. Analytical Chemistry. 82: 9631-5. PMID 21062022 DOI: 10.1021/Ac102496M  0.768
2010 Bui TV, Mendell JT. Myc: Maestro of MicroRNAs. Genes & Cancer. 1: 568-575. PMID 20882107 DOI: 10.1177/1947601910377491  0.5
2010 Yang Y, Chaerkady R, Kandasamy K, Huang TC, Selvan LD, Dwivedi SB, Kent OA, Mendell JT, Pandey A. Identifying targets of miR-143 using a SILAC-based proteomic approach. Molecular Biosystems. 6: 1873-82. PMID 20544124 DOI: 10.1039/C004401F  0.589
2010 Yamakuchi M, Lotterman CD, Bao C, Hruban RH, Karim B, Mendell JT, Huso D, Lowenstein CJ. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6334-9. PMID 20308559 DOI: 10.1073/Pnas.0911082107  0.408
2009 Kent OA, Mullendore M, Wentzel EA, López-Romero P, Tan AC, Alvarez H, West K, Ochs MF, Hidalgo M, Arking DE, Maitra A, Mendell JT. A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. Cancer Biology & Therapy. 8: 2013-24. PMID 20037478 DOI: 10.4161/Cbt.8.21.9685  0.613
2009 Ribas J, Ni X, Haffner M, Wentzel EA, Salmasi AH, Chowdhury WH, Kudrolli TA, Yegnasubramanian S, Luo J, Rodriguez R, Mendell JT, Lupold SE. miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth. Cancer Research. 69: 7165-9. PMID 19738047 DOI: 10.1158/0008-5472.Can-09-1448  0.496
2009 Mendell JT. Tumors line up for a letdown. Nature Genetics. 41: 768-9. PMID 19557079 DOI: 10.1038/ng0709-768  0.529
2009 Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 137: 1005-17. PMID 19524505 DOI: 10.1016/J.Cell.2009.04.021  0.799
2009 Chivukula RR, Mendell JT. Abate and switch: miR-145 in stem cell differentiation. Cell. 137: 606-8. PMID 19450510 DOI: 10.1016/J.Cell.2009.04.059  0.728
2009 Lee KH, Lotterman C, Karikari C, Omura N, Feldmann G, Habbe N, Goggins MG, Mendell JT, Maitra A. Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 9: 293-301. PMID 19407485 DOI: 10.1159/000186051  0.555
2009 Hwang HW, Wentzel EA, Mendell JT. Cell-cell contact globally activates microRNA biogenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 7016-21. PMID 19359480 DOI: 10.1073/pnas.0811523106  0.802
2009 Yang Y, Chaerkady R, Beer MA, Mendell JT, Pandey A. Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics. 9: 1374-84. PMID 19253296 DOI: 10.1002/Pmic.200800551  0.586
2009 Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV. C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism Nature. 458: 762-765. PMID 19219026 DOI: 10.1038/Nature07823  0.383
2009 Habbe N, Koorstra JB, Mendell JT, Offerhaus GJ, Ryu JK, Feldmann G, Mullendore ME, Goggins MG, Hong SM, Maitra A. MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biology & Therapy. 8: 340-6. PMID 19106647 DOI: 10.4161/cbt.8.4.7338  0.462
2008 Yu X, Lin J, Zack DJ, Mendell JT, Qian J. Analysis of regulatory network topology reveals functionally distinct classes of microRNAs. Nucleic Acids Research. 36: 6494-503. PMID 18927108 DOI: 10.1093/Nar/Gkn712  0.499
2008 Chivukula RR, Mendell JT. Circular reasoning: microRNAs and cell-cycle control. Trends in Biochemical Sciences. 33: 474-81. PMID 18774719 DOI: 10.1016/J.Tibs.2008.06.008  0.782
2008 Lotterman CD, Kent OA, Mendell JT. Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle (Georgetown, Tex.). 7: 2493-9. PMID 18719378 DOI: 10.4161/cc.7.16.6452  0.526
2008 Chung EY, Dews M, Cozma D, Yu D, Wentzel EA, Chang TC, Schelter JM, Cleary MA, Mendell JT, Thomas-Tikhonenko A. c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster. Cancer Biology & Therapy. 7: 1758-64. PMID 18708755 DOI: 10.4161/Cbt.7.11.6722  0.685
2008 Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell. 133: 217-22. PMID 18423194 DOI: 10.1016/j.cell.2008.04.001  0.574
2008 Harris TA, Yamakuchi M, Ferlito M, Mendell JT, Lowenstein CJ. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proceedings of the National Academy of Sciences of the United States of America. 105: 1516-21. PMID 18227515 DOI: 10.1073/Pnas.0707493105  0.331
2008 Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM, Dang CV, Thomas-Tikhonenko A, Mendell JT. Widespread microRNA repression by Myc contributes to tumorigenesis Nature Genetics. 40: 43-50. PMID 18066065 DOI: 10.1038/Ng.2007.30  0.754
2007 Bruchova H, Yoon D, Agarwal AM, Mendell J, Prchal JT. Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Experimental Hematology. 35: 1657-67. PMID 17976518 DOI: 10.1016/J.Exphem.2007.08.021  0.527
2007 Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Molecular Cell. 26: 745-52. PMID 17540599 DOI: 10.1016/J.Molcel.2007.05.010  0.547
2007 Chang TC, Mendell JT. microRNAs in vertebrate physiology and human disease. Annual Review of Genomics and Human Genetics. 8: 215-39. PMID 17506656 DOI: 10.1146/annurev.genom.8.080706.092351  0.508
2007 Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. British Journal of Cancer. 96: R40-4. PMID 17393584  0.808
2007 Hwang HW, Wentzel EA, Mendell JT. A hexanucleotide element directs microRNA nuclear import. Science (New York, N.Y.). 315: 97-100. PMID 17204650 DOI: 10.1126/science.1136235  0.814
2007 Chung EY, Cozma D, Yu D, Dews M, Wentzel EA, Chang T, Mendell JT, Thomas-Tikhonenko A. Pax5 Activates Oncogenic Transcription Factors of the Ets Family by Repressing the mir-15a/16-1 microRNA Cluster. Blood. 110: 346-346. DOI: 10.1182/Blood.V110.11.346.346  0.692
2006 Kent OA, Mendell JT. A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene. 25: 6188-96. PMID 17028598 DOI: 10.1038/sj.onc.1209913  0.51
2006 Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, Furth EE, Lee WM, Enders GH, Mendell JT, Thomas-Tikhonenko A. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nature Genetics. 38: 1060-5. PMID 16878133 DOI: 10.1038/Ng1855  0.659
2006 Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT, Jiang J, Schmittgen TD, Patel T. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology. 130: 2113-29. PMID 16762633 DOI: 10.1053/j.gastro.2006.02.057  0.441
2006 Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. British Journal of Cancer. 94: 776-80. PMID 16495913 DOI: 10.1038/sj.bjc.6603023  0.808
2006 Jones KA, Phillips JD, Mendell JT, Glenn MG, Yu MK. Upregulation of SOCS-1 and Downregulation of miR-214 Correlate with Disease Course in Chronic Lymphocytic Leukemia. Blood. 108: 4313-4313. DOI: 10.1182/blood.v108.11.4313.4313  0.602
2006 Bruchova H, Gaikwad AS, Mendell J, Prchal JT. Dysregulated Expression of miRNAs in Polycythemia Vera Erythroid Progenitors. Blood. 108: 3613-3613. DOI: 10.1182/Blood.V108.11.3613.3613  0.652
2006 Yu MK, Mendell JT, Glenn MG, Chen Z, Jones KA, Phillips JD. DNA Methylation Inhibitors Upregulate MiRNA Expression in Patients with Chronic Lymphocytic Leukemia. Blood. 108: 2257-2257. DOI: 10.1182/blood.v108.11.2257.2257  0.426
2005 Mendell JT. MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle (Georgetown, Tex.). 4: 1179-84. PMID 16096373 DOI: 10.4161/cc.4.9.2032  0.593
2005 O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature. 435: 839-43. PMID 15944709 DOI: 10.1038/Nature03677  0.557
2004 Mendell JT, Sharifi NA, Meyers JL, Martinez-Murillo F, Dietz HC. Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise. Nature Genetics. 36: 1073-8. PMID 15448691 DOI: 10.1038/Ng1429  0.51
2002 Mendell JT, ap Rhys CM, Dietz HC. Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts. Science (New York, N.Y.). 298: 419-22. PMID 12228722 DOI: 10.1126/Science.1074428  0.488
2002 Mendell JT, Dietz HC. When the message goes awry: disease-producing mutations that influence mRNA content and performance. Cell. 107: 411-4. PMID 11719181 DOI: 10.1016/S0092-8674(01)00583-9  0.436
2001 Medghalchi SM, Frischmeyer PA, Mendell JT, Kelly AG, Lawler AM, Dietz HC. Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Human Molecular Genetics. 10: 99-105. PMID 11152657 DOI: 10.1093/Hmg/10.2.99  0.508
2000 Mendell JT, Medghalchi SM, Lake RG, Noensie EN, Dietz HC. Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes. Molecular and Cellular Biology. 20: 8944-57. PMID 11073994 DOI: 10.1128/Mcb.20.23.8944-8957.2000  0.698
Low-probability matches (unlikely to be authored by this person)
2015 Wu L, Nguyen LH, Zhou K, de Soysa TY, Li L, Miller JB, Tian J, Locker J, Zhang S, Shinoda G, Seligson MT, Zeitels LR, Acharya A, Wang SC, Mendell JT, et al. Precise let-7 expression levels balance organ regeneration against tumor suppression. Elife. 4. PMID 26445246 DOI: 10.7554/Elife.09431  0.294
2020 Krzeszinski JY, Wei W, Huynh H, Jin Z, Wang X, Chang TC, Xie XJ, He L, Mangala LS, Lopez-Berestein G, Sood AK, Mendell JT, Wan Y. Retraction Note: miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature. 582: 134. PMID 32483375 DOI: 10.1038/S41586-020-2273-1  0.283
2012 Mendell JT. Abstract IA15: MicroRNA reprogramming in cancer: mechanisms and consequences Cancer Research. 72: IA15-IA15. DOI: 10.1158/1538-7445.NONRNA12-IA15  0.255
2018 Chen KS, Stroup EK, Budhipramono A, Rakheja D, Nichols-Vinueza D, Xu L, Stuart SH, Shukla AA, Fraire C, Mendell JT, Amatruda JF. Mutations in microRNA processing genes in Wilms tumors derepress the regulator . Genes & Development. PMID 30026293 DOI: 10.1101/Gad.313783.118  0.238
2019 Manjunath H, Zhang H, Rehfeld F, Han J, Chang TC, Mendell JT. Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection. Cell Reports. 29: 3134-3146.e6. PMID 31801078 DOI: 10.1016/j.celrep.2019.10.129  0.234
2018 Hunter RW, Liu Y, Manjunath H, Acharya A, Jones BT, Zhang H, Chen B, Ramalingam H, Hammer RE, Xie Y, Richardson JA, Rakheja D, Carroll TJ, Mendell JT. Loss of partially phenocopies Perlman syndrome in mice and results in up-regulation of in nephron progenitor cells. Genes & Development. PMID 29950491 DOI: 10.1101/gad.315804.118  0.22
2024 Cheng Y, Wang S, Zhang H, Lee JS, Ni C, Guo J, Chen E, Wang S, Acharya A, Chang TC, Buszczak M, Zhu H, Mendell JT. A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence. Cell. PMID 38981482 DOI: 10.1016/j.cell.2024.06.019  0.218
2017 Dogeas E, Chen B, Xie Y, Mendell J, Augustine MM. Complementary Genome-Wide, Loss- and Gain-of-Function Screens Discover Novel Genes Associated with Platinum Resistance in Colon Adenocarcinoma Journal of the American College of Surgeons. 225: S187-S188. DOI: 10.1016/J.Jamcollsurg.2017.07.427  0.217
2019 Krzeszinski JY, Wei W, Huynh H, Jin Z, Wang X, Chang TC, Xie XJ, He L, Mangala LS, Lopez-Berestein G, Sood AK, Mendell JT, Wan Y. Author Correction: miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature. PMID 31127195 DOI: 10.1038/S41586-019-1266-4  0.208
2024 Hu L, Zhang Y, Guo L, Zhong H, Xie L, Zhou J, Liao C, Yao H, Fang J, Liu H, Zhang C, Zhang H, Zhu X, Luo M, von Kriegsheim A, ... ... Mendell JT, et al. Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma. Molecular Cell. PMID 38211588 DOI: 10.1016/j.molcel.2023.12.010  0.206
2023 Lafita-Navarro MC, Hao YH, Jiang C, Jang S, Chang TC, Brown IN, Venkateswaran N, Maurais E, Stachera W, Zhang Y, Mundy D, Han J, Tran VM, Mettlen M, Xu L, ... ... Mendell JT, et al. ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells. Cell Reports. 42: 113280. PMID 37851577 DOI: 10.1016/j.celrep.2023.113280  0.204
2025 Lee JS, Dan T, Zhang H, Cheng Y, Rehfeld F, Brugarolas J, Mendell JT. An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation. Molecular Cell. PMID 40185099 DOI: 10.1016/j.molcel.2025.03.006  0.199
2023 Norris ML, Mendell JT. Localization of mRNA to cell protrusions dictates binding partner specificity of the encoded protein. Genes & Development. PMID 36859340 DOI: 10.1101/gad.350320.122  0.192
2023 Mattick JS, Amaral PP, Carninci P, Carpenter S, Chang HY, Chen LL, Chen R, Dean C, Dinger ME, Fitzgerald KA, Gingeras TR, Guttman M, Hirose T, Huarte M, Johnson R, ... ... Mendell JT, et al. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews. Molecular Cell Biology. PMID 36596869 DOI: 10.1038/s41580-022-00566-8  0.191
2024 Lee JS, Dan T, Zhang H, Cheng Y, Rehfeld F, Brugarolas J, Mendell JT. An ultraconserved snoRNA-like element in long noncoding RNA promotes ribosome biogenesis and cell proliferation. Biorxiv : the Preprint Server For Biology. PMID 39091767 DOI: 10.1101/2024.07.23.604857  0.19
2015 Lee S, Kopp F, Chang TC, Sataluri A, Chen B, Sivakumar S, Yu H, Xie Y, Mendell JT. Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins. Cell. PMID 26724866 DOI: 10.1016/J.Cell.2015.12.017  0.184
2019 Kopp F, Elguindy MM, Yalvac ME, Zhang H, Chen B, Gillett FA, Lee S, Sivakumar S, Yu H, Xie Y, Mishra P, Sahenk Z, Mendell JT. PUMILIO hyperactivity drives premature aging of -deficient mice. Elife. 8. PMID 30735131 DOI: 10.7554/Elife.42650  0.184
2024 Zhu X, Cruz VE, Zhang H, Erzberger JP, Mendell JT. Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes. Science (New York, N.Y.). 386: eadq8587. PMID 39571015 DOI: 10.1126/science.adq8587  0.181
2020 Lee JS, Mendell JT. Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination. Molecular Cell. PMID 31924448 DOI: 10.1016/j.molcel.2019.12.011  0.175
2018 Kopp F, Mendell JT. Functional Classification and Experimental Dissection of Long Noncoding RNAs. Cell. 172: 393-407. PMID 29373828 DOI: 10.1016/j.cell.2018.01.011  0.172
2017 Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. Erratum: Publisher Correction: Somatic mutations in and impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nature Communications. 8: 16177. PMID 31305780 DOI: 10.1038/Ncomms16177  0.17
2022 Thomas A, Rehfeld F, Zhang H, Chang TC, Goodarzi M, Gillet F, Mendell JT. RBM33 directs the nuclear export of transcripts containing GC-rich elements. Genes & Development. PMID 35589130 DOI: 10.1101/gad.349456.122  0.165
2020 Zhu X, Zhang H, Mendell JT. Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3' UTR-Directed Regulation and Nonsense-Mediated Decay. Cell Reports. 32: 107895. PMID 32668236 DOI: 10.1016/j.celrep.2020.107895  0.162
2021 Cable J, Heard E, Hirose T, Prasanth KV, Chen LL, Henninger JE, Quinodoz SA, Spector DL, Diermeier SD, Porman AM, Kumar D, Feinberg MW, Shen X, Unfried JP, Johnson R, ... ... Mendell JT, et al. Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34791665 DOI: 10.1111/nyas.14713  0.153
2023 Li X, Wang Y, Deng S, Zhu G, Wang C, Johnson NA, Zhang Z, Tirado CR, Xu Y, Metang LA, Gonzalez J, Mukherji A, Ye J, Yang Y, Peng W, ... ... Mendell JT, et al. Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer. Cancer Cell. PMID 37478850 DOI: 10.1016/j.ccell.2023.06.010  0.144
2019 Elguindy MM, Kopp F, Goodarzi M, Rehfeld F, Thomas A, Chang TC, Mendell JT. PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA . Elife. 8. PMID 31343408 DOI: 10.7554/eLife.48625  0.144
2024 Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS. Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation. Proceedings of the National Academy of Sciences of the United States of America. 121: e2408249121. PMID 39388274 DOI: 10.1073/pnas.2408249121  0.137
2020 Zhang Z, Zhou C, Li X, Barnes SD, Deng S, Hoover E, Chen CC, Lee YS, Zhang Y, Wang C, Metang LA, Wu C, Tirado CR, Johnson NA, Wongvipat J, ... ... Mendell JT, et al. Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation. Cancer Cell. PMID 32220301 DOI: 10.1016/J.Ccell.2020.03.001  0.136
2024 Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS. Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation. Biorxiv : the Preprint Server For Biology. PMID 38712170 DOI: 10.1101/2024.04.24.590974  0.135
2021 Elguindy MM, Mendell JT. NORAD-induced Pumilio phase separation is required for genome stability. Nature. PMID 34108682 DOI: 10.1038/s41586-021-03633-w  0.135
2018 Quirin KA, Kwon JJ, Alioufi A, Factora T, Temm CJ, Jacobsen M, Sandusky GE, Shontz K, Chicoine LG, Clark KR, Mendell JT, Korc M, Kota J. Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice. Molecular Therapy. Methods & Clinical Development. 8: 8-20. PMID 29349096 DOI: 10.1016/j.omtm.2017.09.006  0.128
2023 Rehfeld F, Eitson JL, Ohlson MB, Chang TC, Schoggins JW, Mendell JT. CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication. Cell Reports. 42: 112076. PMID 36753415 DOI: 10.1016/j.celrep.2023.112076  0.122
2024 Lin CC, Chang TC, Wang Y, Guo L, Gao Y, Bikorimana E, Lemoff A, Fang YV, Zhang H, Zhang Y, Ye D, Soria-Bretones I, Servetto A, Lee KM, Luo X, ... ... Mendell JT, et al. PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer. Nature Communications. 15: 2287. PMID 38480701 DOI: 10.1038/s41467-024-46495-2  0.121
2016 Mendell JT. Targeting a Long Noncoding RNA in Breast Cancer. The New England Journal of Medicine. 374: 2287-9. PMID 27276568 DOI: 10.1056/NEJMcibr1603785  0.118
2023 Banerjee PR, Holehouse AS, Kriwacki R, Robustelli P, Jiang H, Sobolevsky AI, Hurley JM, Mendell JT. Dissecting the biophysics and biology of intrinsically disordered proteins. Trends in Biochemical Sciences. PMID 37949765 DOI: 10.1016/j.tibs.2023.10.002  0.117
2013 Lieberman J, Slack F, Pandolfi PP, Chinnaiyan A, Agami R, Mendell JT. Noncoding RNAs and cancer. Cell. 153: 9-10. PMID 23781554 DOI: 10.1016/J.Cell.2013.03.019  0.117
2023 Lin CC, Chang TC, Wang Y, Guo L, Gao Y, Bikorimana E, Lemoff A, Fang Y, Zhang H, Zhang Y, Ye D, Soria-Bretones I, Servetto A, Lee KM, Luo X, ... ... Mendell J, et al. Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer. Research Square. PMID 37502925 DOI: 10.21203/rs.3.rs-2966905/v1  0.112
2015 Pertea M, Pertea GM, Antonescu CM, Chang TC, Mendell JT, Salzberg SL. StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nature Biotechnology. 33: 290-5. PMID 25690850 DOI: 10.1038/Nbt.3122  0.103
1998 Mendell JT, Panicker SG, Tsao CY, Feng B, Sahenk Z, Marzluf GA, Mendell JR. Novel compound heterozygous laminina2-chain gene (LAMA2) mutations in congenital muscular dystrophy. Mutations in brief no. 159. Online. Human Mutation. 12: 135. PMID 10694916 DOI: 10.1002/(SICI)1098-1004(1998)12:2<135::AID-HUMU10>3.0.CO;2-6  0.09
2020 Suresh S, Chen B, Zhu J, Golden RJ, Lu C, Evers BM, Novaresi N, Smith B, Zhan X, Schmid V, Jun S, Karacz CM, Peyton M, Zhong L, Wen Z, ... ... Mendell JT, et al. eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer. Nature Cancer. 1: 533-545. PMID 32984844 DOI: 10.1038/S43018-020-0056-0  0.083
2014 Chen B, Yun J, Kim MS, Mendell JT, Xie Y. PIPE-CLIP: a comprehensive online tool for CLIP-seq data analysis. Genome Biology. 15: R18. PMID 24451213 DOI: 10.1186/gb-2014-15-1-r18  0.082
2018 Dogeas E, Chen B, Xie Y, Mendell J, Augustine M. Novel cell membrane cation transporter associated with platinum therapy resistance in pancreatic adenocarcinoma identified through CRISPR/Cas9 loss-of- function screen Hpb. 20: S25. DOI: 10.1016/j.hpb.2018.02.050  0.081
1999 Panicker SG, Mendell JT, Chen L, Feng B, Sahenk Z, Marzluf GA, Amato AA, Mendell JR. Novel single base polymorphisms and rare sequence variants in the laminin ?2-chain coding region detected by RNA/SSCP analysis Human Mutation. 13: 174-174. DOI: 10.1002/(Sici)1098-1004(1999)13:2<174::Aid-Humu24>3.0.Co;2-P  0.079
2020 Suresh S, Chen B, Zhu J, Golden RJ, Lu C, Evers BM, Novaresi N, Smith B, Zhan X, Schmid V, Jun S, Karacz CM, Peyton M, Zhong L, Wen Z, ... ... Mendell JT, et al. eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer Nature Cancer. 1: 533-545. DOI: 10.1038/s43018-020-0056-0  0.042
2020 Trinh MN, Brown MS, Goldstein JL, Han J, Vale G, McDonald JG, Seemann J, Mendell JT, Lu F. Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690708 DOI: 10.1073/Pnas.2010682117  0.037
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