| Year |
Citation |
Score |
| 2024 |
Hung KL, Jones MG, Wong IT, Curtis EJ, Lange JT, He BJ, Luebeck J, Schmargon R, Scanu E, Brückner L, Yan X, Li R, Gnanasekar A, Chamorro González R, Belk JA, ... ... Chang HY, et al. Coordinated inheritance of extrachromosomal DNAs in cancer cells. Nature. 635: 201-209. PMID 39506152 DOI: 10.1038/s41586-024-07861-8 |
0.765 |
|
| 2024 |
Bailey C, Pich O, Thol K, Watkins TBK, Luebeck J, Rowan A, Stavrou G, Weiser NE, Dameracharla B, Bentham R, Lu WT, Kittel J, Yang SYC, Howitt BE, Sharma N, ... ... Chang HY, et al. Origins and impact of extrachromosomal DNA. Nature. 635: 193-200. PMID 39506150 DOI: 10.1038/s41586-024-08107-3 |
0.751 |
|
| 2024 |
Ashkin EL, Tang YJ, Xu H, Hung KL, Belk J, Cai H, Lopez S, Dolcen DN, Hebert JD, Li R, Ruiz PA, Keal T, Andrejka L, Chang HY, Petrov DA, et al. A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis. Biorxiv : the Preprint Server For Biology. PMID 39345539 DOI: 10.1101/2024.09.14.613043 |
0.742 |
|
| 2024 |
Kraft K, Murphy SE, Jones MG, Shi Q, Bhargava-Shah A, Luong C, Hung KL, He BJ, Li R, Park SK, Weiser NE, Luebeck J, Bafna V, Boeke JD, Mischel PS, ... ... Chang HY, et al. Enhancer activation from transposable elements in extrachromosomal DNA. Biorxiv : the Preprint Server For Biology. PMID 39282372 DOI: 10.1101/2024.09.04.611262 |
0.8 |
|
| 2024 |
Rose JC, Belk JA, Wong IT, Luebeck J, Horn HT, Daniel B, Jones MG, Yost KE, Hung KL, Kolahi KS, Curtis EJ, Kuo CJ, Bafna V, Mischel PS, Chang HY. Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair. Cancer Discovery. PMID 39109936 DOI: 10.1158/2159-8290.CD-23-1117 |
0.728 |
|
| 2024 |
Amaya L, Abe B, Liu J, Zhao F, Zhang WL, Chen R, Li R, Wang S, Kamber RA, Tsai MC, Bassik MC, Majeti R, Chang HY. Pathways for macrophage uptake of cell-free circular RNAs. Molecular Cell. PMID 38761795 DOI: 10.1016/j.molcel.2024.04.022 |
0.607 |
|
| 2024 |
Pacalin NM, Steinhart Z, Shi Q, Belk JA, Dorovskyi D, Kraft K, Parker KR, Shy BR, Marson A, Chang HY. Bidirectional epigenetic editing reveals hierarchies in gene regulation. Nature Biotechnology. PMID 38760566 DOI: 10.1038/s41587-024-02213-3 |
0.632 |
|
| 2024 |
Li Z, Amaya L, Ee A, Wang SK, Ranjan A, Waymouth RM, Chang HY, Wender PA. Organ- and Cell-Selective Delivery of mRNA In Vivo Using Guanidinylated Serinol Charge-Altering Releasable Transporters. Journal of the American Chemical Society. PMID 38743019 DOI: 10.1021/jacs.4c02704 |
0.659 |
|
| 2024 |
Agrawal S, Buyan A, Severin J, Koido M, Alam T, Abugessaisa I, Chang HY, Dostie J, Itoh M, Kere J, Kondo N, Li Y, Makeev VJ, Mendez M, Okazaki Y, et al. Annotation of nuclear lncRNAs based on chromatin interactions. Plos One. 19: e0295971. PMID 38709794 DOI: 10.1371/journal.pone.0295971 |
0.338 |
|
| 2024 |
Wang G, Lee-Yow Y, Chang HY. Approaches to probe and perturb long noncoding RNA functions in diseases. Current Opinion in Genetics & Development. 85: 102158. PMID 38412563 DOI: 10.1016/j.gde.2024.102158 |
0.325 |
|
| 2024 |
Zhu K, Jones MG, Luebeck J, Bu X, Yi H, Hung KL, Wong IT, Zhang S, Mischel PS, Chang HY, Bafna V. CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing. Biorxiv : the Preprint Server For Biology. PMID 38405779 DOI: 10.1101/2024.02.15.580594 |
0.747 |
|
| 2024 |
Dou DR, Zhao Y, Belk JA, Zhao Y, Casey KM, Chen DC, Li R, Yu B, Srinivasan S, Abe BT, Kraft K, Hellström C, Sjöberg R, Chang S, Feng A, ... ... Chang HY, et al. Xist ribonucleoproteins promote female sex-biased autoimmunity. Cell. 187: 733-749.e16. PMID 38306984 DOI: 10.1016/j.cell.2023.12.037 |
0.564 |
|
| 2023 |
Rose JC, Wong IT, Daniel B, Jones MG, Yost KE, Hung KL, Curtis EJ, Mischel PS, Chang HY. Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair. Biorxiv : the Preprint Server For Biology. PMID 37961138 DOI: 10.1101/2023.10.22.563489 |
0.727 |
|
| 2023 |
Chapman OS, Luebeck J, Sridhar S, Wong IT, Dixit D, Wang S, Prasad G, Rajkumar U, Pagadala MS, Larson JD, He BJ, Hung KL, Lange JT, Dehkordi SR, Chandran S, ... ... Chang HY, et al. Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma. Nature Genetics. PMID 37945900 DOI: 10.1038/s41588-023-01551-3 |
0.733 |
|
| 2023 |
Yu M, Nie Y, Yang J, Yang S, Li R, Rao V, Hu X, Fang C, Li S, Song D, Guo F, Snyder MP, Chang HY, Kuo CJ, Xu J, et al. Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease. Cell Reports. 42: 113392. PMID 37925638 DOI: 10.1016/j.celrep.2023.113392 |
0.402 |
|
| 2023 |
Li Z, Amaya L, Pi R, Wang SK, Ranjan A, Waymouth RM, Blish CA, Chang HY, Wender PA. Charge-altering releasable transporters enhance mRNA delivery in vitro and exhibit in vivo tropism. Nature Communications. 14: 6983. PMID 37914693 DOI: 10.1038/s41467-023-42672-x |
0.617 |
|
| 2023 |
Berson E, Sreenivas A, Phongpreecha T, Perna A, Grandi FC, Xue L, Ravindra NG, Payrovnaziri N, Mataraso S, Kim Y, Espinosa C, Chang AL, Becker M, Montine KS, Fox EJ, ... Chang HY, et al. Whole genome deconvolution unveils Alzheimer's resilient epigenetic signature. Nature Communications. 14: 4947. PMID 37587197 DOI: 10.1038/s41467-023-40611-4 |
0.762 |
|
| 2023 |
Hung KL, Jones MG, Wong IT, Lange JT, Luebeck J, Scanu E, He BJ, Brückner L, Li R, González RC, Schmargon R, Dörr JR, Belk JA, Bafna V, Werner B, ... ... Chang HY, et al. Coordinated inheritance of extrachromosomal DNA species in human cancer cells. Biorxiv : the Preprint Server For Biology. PMID 37503111 DOI: 10.1101/2023.07.18.549597 |
0.762 |
|
| 2023 |
Chamorro González R, Conrad T, Stöber MC, Xu R, Giurgiu M, Rodriguez-Fos E, Kasack K, Brückner L, van Leen E, Helmsauer K, Dorado Garcia H, Stefanova ME, Hung KL, Bei Y, Schmelz K, ... ... Chang HY, et al. Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature Genetics. 55: 880-890. PMID 37142849 DOI: 10.1038/s41588-023-01386-y |
0.784 |
|
| 2023 |
Gonzalez-Sandoval A, Pekrun K, Tsuji S, Zhang F, Hung KL, Chang HY, Kay MA. The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner. Nature Communications. 14: 2448. PMID 37117181 DOI: 10.1038/s41467-023-38106-3 |
0.752 |
|
| 2023 |
Chang HY, Qi LS. Reversing the Central Dogma: RNA-guided control of DNA in epigenetics and genome editing. Molecular Cell. 83: 442-451. PMID 36736311 DOI: 10.1016/j.molcel.2023.01.010 |
0.322 |
|
| 2023 |
Chen LL, Bindereif A, Bozzoni I, Chang HY, Matera AG, Gorospe M, Hansen TB, Kjems J, Ma XK, Pek JW, Rajewsky N, Salzman J, Wilusz JE, Yang L, Zhao F. A guide to naming eukaryotic circular RNAs. Nature Cell Biology. PMID 36658223 DOI: 10.1038/s41556-022-01066-9 |
0.578 |
|
| 2023 |
Mattick JS, Amaral PP, Carninci P, Carpenter S, Chang HY, Chen LL, Chen R, Dean C, Dinger ME, Fitzgerald KA, Gingeras TR, Guttman M, Hirose T, Huarte M, Johnson R, et al. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews. Molecular Cell Biology. PMID 36596869 DOI: 10.1038/s41580-022-00566-8 |
0.747 |
|
| 2022 |
Haddad Derafshi B, Danko T, Chanda S, Batista PJ, Litzenburger U, Lee QY, Ng YH, Sebin A, Chang HY, Südhof TC, Wernig M. The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1. Scientific Reports. 12: 22425. PMID 36575212 DOI: 10.1038/s41598-022-23614-x |
0.678 |
|
| 2022 |
Wang SK, Nair S, Li R, Kraft K, Pampari A, Patel A, Kang JB, Luong C, Kundaje A, Chang HY. Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases. Cell Genomics. 2. PMID 36277849 DOI: 10.1016/j.xgen.2022.100164 |
0.735 |
|
| 2022 |
Hung KL, Luebeck J, Dehkordi SR, Colón CI, Li R, Wong IT, Coruh C, Dharanipragada P, Lomeli SH, Weiser NE, Moriceau G, Zhang X, Bailey C, Houlahan KE, Yang W, ... ... Chang HY, et al. Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH. Nature Genetics. PMID 36253572 DOI: 10.1038/s41588-022-01190-0 |
0.746 |
|
| 2022 |
Lange JT, Rose JC, Chen CY, Pichugin Y, Xie L, Tang J, Hung KL, Yost KE, Shi Q, Erb ML, Rajkumar U, Wu S, Taschner-Mandl S, Bernkopf M, Swanton C, ... ... Chang HY, et al. The evolutionary dynamics of extrachromosomal DNA in human cancers. Nature Genetics. PMID 36123406 DOI: 10.1038/s41588-022-01177-x |
0.745 |
|
| 2022 |
Moonen JR, Chappell J, Shi M, Shinohara T, Li D, Mumbach MR, Zhang F, Nair RV, Nasser J, Mai DH, Taylor S, Wang L, Metzger RJ, Chang HY, Engreitz JM, et al. KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress. Nature Communications. 13: 4941. PMID 35999210 DOI: 10.1038/s41467-022-32566-9 |
0.399 |
|
| 2022 |
Chen R, Wang SK, Belk JA, Amaya L, Li Z, Cardenas A, Abe BT, Chen CK, Wender PA, Chang HY. Author Correction: Engineering circular RNA for enhanced protein production. Nature Biotechnology. PMID 35978134 DOI: 10.1038/s41587-022-01472-2 |
0.643 |
|
| 2022 |
Hung KL, Mischel PS, Chang HY. Gene regulation on extrachromosomal DNA. Nature Structural & Molecular Biology. 29: 736-744. PMID 35948767 DOI: 10.1038/s41594-022-00806-7 |
0.762 |
|
| 2022 |
Chen R, Wang SK, Belk JA, Amaya L, Li Z, Cardenas A, Abe BT, Chen CK, Wender PA, Chang HY. Engineering circular RNA for enhanced protein production. Nature Biotechnology. PMID 35851375 DOI: 10.1038/s41587-022-01393-0 |
0.689 |
|
| 2022 |
Kraft K, Yost KE, Murphy SE, Magg A, Long Y, Corces MR, Granja JM, Wittler L, Mundlos S, Cech TR, Boettiger AN, Chang HY. Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation. Proceedings of the National Academy of Sciences of the United States of America. 119: e2201883119. PMID 35617427 DOI: 10.1073/pnas.2201883119 |
0.674 |
|
| 2022 |
Raj N, Wang M, Seoane JA, Zhao RL, Kaiser AM, Moonie NA, Demeter J, Boutelle AM, Kerr CH, Mulligan AS, Moffatt C, Zeng SX, Lu H, Barna M, Curtis C, ... Chang HY, et al. The Mettl3 epitranscriptomic writer amplifies p53 stress responses. Molecular Cell. PMID 35512709 DOI: 10.1016/j.molcel.2022.04.010 |
0.501 |
|
| 2022 |
Xie L, Dong P, Qi Y, Hsieh TS, English BP, Jung S, Chen X, De Marzio M, Casellas R, Chang HY, Zhang B, Tjian R, Liu Z. BRD2 compartmentalizes the accessible genome. Nature Genetics. 54: 481-491. PMID 35410381 DOI: 10.1038/s41588-022-01044-9 |
0.671 |
|
| 2022 |
Weiser NE, Hung KL, Chang HY. Oncogene Convergence in Extrachromosomal DNA Hubs. Cancer Discovery. 12: 1195-1198. PMID 35398879 DOI: 10.1158/2159-8290.CD-22-0076 |
0.73 |
|
| 2022 |
Bailey AS, Batista PJ, Chang HY, Fuller MT. Identification of Protein-RNA Interactions in Mouse Testis Tissue Using fRIP. Bio-Protocol. 12: e4286. PMID 35118177 DOI: 10.21769/BioProtoc.4286 |
0.712 |
|
| 2022 |
Meijer M, Agirre E, Kabbe M, van Tuijn CA, Heskol A, Zheng C, Mendanha Falcão A, Bartosovic M, Kirby L, Calini D, Johnson MR, Corces MR, Montine TJ, Chen X, Chang HY, et al. Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility. Neuron. PMID 35093191 DOI: 10.1016/j.neuron.2021.12.034 |
0.701 |
|
| 2021 |
Hung KL, Yost KE, Xie L, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, Chamorro González R, Weiser NE, Chen C, Valieva ME, Wong IT, Wu S, Dehkordi SR, ... ... Chang HY, et al. ecDNA hubs drive cooperative intermolecular oncogene expression. Nature. PMID 34819668 DOI: 10.1038/s41586-021-04116-8 |
0.813 |
|
| 2021 |
Cable J, Heard E, Hirose T, Prasanth KV, Chen LL, Henninger JE, Quinodoz SA, Spector DL, Diermeier SD, Porman AM, Kumar D, Feinberg MW, Shen X, Unfried JP, Johnson R, ... ... Chang HY, et al. Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34791665 DOI: 10.1111/nyas.14713 |
0.607 |
|
| 2021 |
Richards RM, Zhao F, Freitas KA, Parker KR, Xu P, Fan A, Sotillo E, Daugaard M, Oo HZ, Liu J, Hong WJ, Sorensen PH, Chang HY, Satpathy AT, Majzner RG, et al. NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity. Blood Cancer Discovery. 2: 648-665. PMID 34778803 DOI: 10.1158/2643-3230.BCD-20-0208 |
0.497 |
|
| 2021 |
Kim DS, Risca VI, Reynolds DL, Chappell J, Rubin AJ, Jung N, Donohue LKH, Lopez-Pajares V, Kathiria A, Shi M, Zhao Z, Deep H, Sharmin M, Rao D, Lin S, ... Chang HY, et al. The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation. Nature Genetics. PMID 34650237 DOI: 10.1038/s41588-021-00947-3 |
0.39 |
|
| 2021 |
Sanghi A, Gruber JJ, Metwally A, Jiang L, Reynolds W, Sunwoo J, Orloff L, Chang HY, Kasowski M, Snyder MP. Chromatin accessibility associates with protein-RNA correlation in human cancer. Nature Communications. 12: 5732. PMID 34593797 DOI: 10.1038/s41467-021-25872-1 |
0.5 |
|
| 2021 |
Chen CK, Cheng R, Demeter J, Chen J, Weingarten-Gabbay S, Jiang L, Snyder MP, Weissman JS, Segal E, Jackson PK, Chang HY. Structured elements drive extensive circular RNA translation. Molecular Cell. PMID 34437836 DOI: 10.1016/j.molcel.2021.07.042 |
0.639 |
|
| 2021 |
Chen L, Chang HY, Artandi SE. Analysis of RNA conformation in endogenously assembled RNPs by icSHAPE. Star Protocols. 2: 100477. PMID 33997809 DOI: 10.1016/j.xpro.2021.100477 |
0.31 |
|
| 2021 |
Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, et al. Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. PMID 33838111 DOI: 10.1016/j.cell.2021.03.025 |
0.776 |
|
| 2021 |
Yu B, Qi Y, Li R, Shi Q, Satpathy AT, Chang HY. B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells. Cell. PMID 33735607 DOI: 10.1016/j.cell.2021.02.015 |
0.302 |
|
| 2020 |
Lu Z, Guo JK, Wei Y, Dou DR, Zarnegar B, Ma Q, Li R, Zhao Y, Liu F, Choudhry H, Khavari PA, Chang HY. Structural modularity of the XIST ribonucleoprotein complex. Nature Communications. 11: 6163. PMID 33268787 DOI: 10.1038/s41467-020-20040-3 |
0.519 |
|
| 2020 |
Corley M, Flynn RA, Lee B, Blue SM, Chang HY, Yeo GW. Footprinting SHAPE-eCLIP Reveals Transcriptome-wide Hydrogen Bonds at RNA-Protein Interfaces. Molecular Cell. PMID 33242392 DOI: 10.1016/j.molcel.2020.11.014 |
0.324 |
|
| 2020 |
Corces MR, Shcherbina A, Kundu S, Gloudemans MJ, Frésard L, Granja JM, Louie BH, Eulalio T, Shams S, Bagdatli ST, Mumbach MR, Liu B, Montine KS, Greenleaf WJ, Kundaje A, ... ... Chang HY, et al. Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer's and Parkinson's diseases. Nature Genetics. PMID 33106633 DOI: 10.1038/s41588-020-00721-x |
0.403 |
|
| 2020 |
Parker KR, Migliorini D, Perkey E, Yost KE, Bhaduri A, Bagga P, Haris M, Wilson NE, Liu F, Gabunia K, Scholler J, Montine TJ, Bhoj VG, Reddy R, Mohan S, ... ... Chang HY, et al. Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies. Cell. PMID 32961131 DOI: 10.1016/J.Cell.2020.08.022 |
0.478 |
|
| 2020 |
Kim H, Nguyen NP, Turner K, Wu S, Gujar AD, Luebeck J, Liu J, Deshpande V, Rajkumar U, Namburi S, Amin SB, Yi E, Menghi F, Schulte JH, Henssen AG, ... Chang HY, et al. Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers. Nature Genetics. PMID 32807987 DOI: 10.1038/S41588-020-0678-2 |
0.342 |
|
| 2020 |
Wilson KD, Ameen M, Guo H, Abilez OJ, Tian L, Mumbach MR, Diecke S, Qin X, Liu Y, Yang H, Ma N, Gaddam S, Cunningham NJ, Gu M, Neofytou E, ... ... Chang HY, et al. Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates. Developmental Cell. PMID 32763147 DOI: 10.1016/J.Devcel.2020.07.006 |
0.414 |
|
| 2020 |
Ramilowski JA, Yip CW, Agrawal S, Chang JC, Ciani Y, Kulakovskiy IV, Mendez M, Ooi JLC, Ouyang JF, Parkinson N, Petri A, Roos L, Severin J, Yasuzawa K, Abugessaisa I, ... ... Chang H, et al. Functional annotation of human long noncoding RNAs via molecular phenotyping. Genome Research. PMID 32718982 DOI: 10.1101/Gr.254219.119 |
0.463 |
|
| 2020 |
Wu KE, Fazal FM, Parker KR, Zou J, Chang HY. RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus. Cell Systems. PMID 32673562 DOI: 10.1016/J.Cels.2020.06.008 |
0.798 |
|
| 2020 |
Rinn JL, Chang HY. Long Noncoding RNAs: Molecular Modalities to Organismal Functions. Annual Review of Biochemistry. 89: 283-308. PMID 32569523 DOI: 10.1146/Annurev-Biochem-062917-012708 |
0.644 |
|
| 2020 |
Ang CE, Trevino AE, Chang HY. Diverse lncRNA mechanisms in brain development and disease. Current Opinion in Genetics & Development. 65: 42-46. PMID 32554106 DOI: 10.1016/J.Gde.2020.05.006 |
0.448 |
|
| 2020 |
Nasrallah R, Imianowski CJ, Bossini-Castillo L, Grant FM, Dogan M, Placek L, Kozhaya L, Kuo P, Sadiyah F, Whiteside SK, Mumbach MR, Glinos D, Vardaka P, Whyte CE, Lozano T, ... ... Chang HY, et al. A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by T cells. Nature. PMID 32499651 DOI: 10.1038/S41586-020-2296-7 |
0.352 |
|
| 2020 |
Fazal FM, Chang HY. Subcellular Spatial Transcriptomes: Emerging Frontier for Understanding Gene Regulation. Cold Spring Harbor Symposia On Quantitative Biology. PMID 32482897 DOI: 10.1101/Sqb.2019.84.040352 |
0.817 |
|
| 2020 |
Carter AC, Xu J, Nakamoto MY, Wei Y, Zarnegar BJ, Shi Q, Broughton JP, Ransom RC, Salhotra A, Nagaraja SD, Li R, Dou DR, Yost KE, Cho SW, Mistry A, ... ... Chang HY, et al. Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation. Elife. 9. PMID 32379046 DOI: 10.7554/Elife.54508 |
0.45 |
|
| 2020 |
Paik DT, Cho S, Tian L, Chang HY, Wu JC. Single-cell RNA sequencing in cardiovascular development, disease and medicine. Nature Reviews. Cardiology. PMID 32231331 DOI: 10.1038/S41569-020-0359-Y |
0.377 |
|
| 2020 |
Lee QY, Mall M, Chanda S, Zhou B, Sharma KS, Schaukowitch K, Adrian-Segarra JM, Grieder SD, Kareta MS, Wapinski OL, Ang CE, Li R, Südhof TC, Chang HY, Wernig M. Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes. Nature Cell Biology. PMID 32231311 DOI: 10.1038/S41556-020-0490-3 |
0.311 |
|
| 2020 |
Wu KE, Parker KR, Fazal FM, Chang H, Zou J. RNA-GPS predicts high-resolution RNA subcellular localization and highlights the role of splicing. Rna (New York, N.Y.). PMID 32220894 DOI: 10.1261/Rna.074161.119 |
0.802 |
|
| 2020 |
Xie L, Dong P, Chen X, Hsieh TS, Banala S, De Marzio M, English BP, Qi Y, Jung SK, Kieffer-Kwon KR, Legant WR, Hansen AS, Schulmann A, Casellas R, Zhang B, ... ... Chang HY, et al. 3D ATAC-PALM: super-resolution imaging of the accessible genome. Nature Methods. PMID 32203384 DOI: 10.1038/S41592-020-0775-2 |
0.699 |
|
| 2020 |
Horlbeck MA, Liu SJ, Chang HY, Lim DA, Weissman JS. Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes. Nature Biotechnology. PMID 32094656 DOI: 10.1038/S41587-020-0428-0 |
0.408 |
|
| 2020 |
Wasson CW, Abignano G, Hermes H, Malaab M, Ross RL, Jimenez SA, Chang HY, Feghali-Bostwick CA, Del Galdo F. Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH. Annals of the Rheumatic Diseases. PMID 32041748 DOI: 10.1136/Annrheumdis-2019-216542 |
0.319 |
|
| 2020 |
Li Y, Gruber JJ, Litzenburger UM, Zhou Y, Miao YR, LaGory EL, Li AM, Hu Z, Yip M, Hart LS, Maris JM, Chang HY, Giaccia AJ, Ye J. Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia. Cell Death & Disease. 11: 102. PMID 32029721 DOI: 10.1038/S41419-020-2303-9 |
0.335 |
|
| 2020 |
Stadtmauer EA, Fraietta JA, Davis MM, Cohen AD, Weber KL, Lancaster E, Mangan PA, Kulikovskaya I, Gupta M, Chen F, Tian L, Gonzalez VE, Xu J, Jung IY, Melenhorst JJ, ... ... Chang HY, et al. CRISPR-engineered T cells in patients with refractory cancer. Science (New York, N.Y.). PMID 32029687 DOI: 10.1126/Science.Aba7365 |
0.344 |
|
| 2020 |
Trevino AE, Sinnott-Armstrong N, Andersen J, Yoon SJ, Huber N, Pritchard JK, Chang HY, Greenleaf WJ, Pașca SP. Chromatin accessibility dynamics in a model of human forebrain development. Science (New York, N.Y.). 367. PMID 31974223 DOI: 10.1126/Science.Aay1645 |
0.343 |
|
| 2020 |
Carter AC, Xu J, Nakamoto MY, Wei Y, Zarnegar BJ, Shi Q, Broughton JP, Ransom RC, Salhotra A, Nagaraja SD, Li R, Dou DR, Yost KE, Cho S, Mistry A, ... ... Chang HY, et al. Author response: Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation Elife. DOI: 10.7554/Elife.54508.Sa2 |
0.353 |
|
| 2020 |
Chang HY. Abstract PL01-01: Personal regulome navigation of cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Pl01-01 |
0.374 |
|
| 2020 |
Ramilowski JA, Yip CW, Agrawal S, Chang J, Ciani Y, Kulakovskiy IV, Mendez M, Ooi JLC, Ouyang JF, Parkinson N, Petri A, Roos L, Severin J, Yasuzawa K, Abugessaisa I, ... ... Chang H, et al. Corrigendum: Functional annotation of human long noncoding RNAs via molecular phenotyping Genome Research. 30: 1377-1-1377-1. DOI: 10.1101/Gr.270330.120 |
0.404 |
|
| 2019 |
Fang J, Ma Q, Chu C, Huang B, Li L, Cai P, Batista PJ, Tolentino KEM, Xu J, Li R, Du P, Qu K, Chang HY. PIRCh-seq: functional classification of non-coding RNAs associated with distinct histone modifications. Genome Biology. 20: 292. PMID 31862000 DOI: 10.1186/S13059-019-1880-3 |
0.73 |
|
| 2019 |
Yost KE, Chang HY, Satpathy AT. Tracking the immune response with single-cell genomics. Vaccine. PMID 31859202 DOI: 10.1016/J.Vaccine.2019.11.035 |
0.31 |
|
| 2019 |
Esfahani MS, Lee LJ, Jeon YJ, Flynn RA, Stehr H, Hui AB, Ishisoko N, Kildebeck E, Newman AM, Bratman SV, Porteus MH, Chang HY, Alizadeh AA, Diehn M. Functional significance of U2AF1 S34F mutations in lung adenocarcinomas. Nature Communications. 10: 5712. PMID 31836708 DOI: 10.1038/S41467-019-13392-Y |
0.659 |
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| 2019 |
Lynn RC, Weber EW, Sotillo E, Gennert D, Xu P, Good Z, Anbunathan H, Lattin J, Jones R, Tieu V, Nagaraja S, Granja J, de Bourcy CFA, Majzner R, Satpathy AT, ... ... Chang HY, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. PMID 31802004 DOI: 10.1038/S41586-019-1805-Z |
0.315 |
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| 2019 |
Granja JM, Klemm S, McGinnis LM, Kathiria AS, Mezger A, Corces MR, Parks B, Gars E, Liedtke M, Zheng GXY, Chang HY, Majeti R, Greenleaf WJ. Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia. Nature Biotechnology. PMID 31792411 DOI: 10.1038/S41587-019-0332-7 |
0.789 |
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| 2019 |
Wu S, Turner KM, Nguyen N, Raviram R, Erb M, Santini J, Luebeck J, Rajkumar U, Diao Y, Li B, Zhang W, Jameson N, Corces MR, Granja JM, Chen X, ... ... Chang HY, et al. Circular ecDNA promotes accessible chromatin and high oncogene expression. Nature. PMID 31748743 DOI: 10.1038/S41586-019-1763-5 |
0.728 |
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| 2019 |
López-Isac E, Acosta-Herrera M, Kerick M, Assassi S, Satpathy AT, Granja J, Mumbach MR, Beretta L, Simeón CP, Carreira P, Ortego-Centeno N, Castellvi I, Bossini-Castillo L, Carmona FD, Orozco G, ... ... Chang HY, et al. GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways. Nature Communications. 10: 4955. PMID 31672989 DOI: 10.1038/S41467-019-12760-Y |
0.306 |
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| 2019 |
Chen YG, Chen R, Ahmad S, Verma R, Kasturi SP, Amaya L, Broughton JP, Kim J, Cadena C, Pulendran B, Hur S, Chang HY. N6-Methyladenosine Modification Controls Circular RNA Immunity. Molecular Cell. PMID 31474572 DOI: 10.1016/J.Molcel.2019.07.016 |
0.371 |
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| 2019 |
Bousard A, Raposo AC, Żylicz JJ, Picard C, Pires VB, Qi Y, Gil C, Syx L, Chang HY, Heard E, da Rocha ST. The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation. Embo Reports. e48019. PMID 31456285 DOI: 10.15252/Embr.201948019 |
0.427 |
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| 2019 |
Durai V, Bagadia P, Granja JM, Satpathy AT, Kulkarni DH, Davidson JT, Wu R, Patel SJ, Iwata A, Liu TT, Huang X, Briseño CG, Grajales-Reyes GE, Wöhner M, Tagoh H, ... ... Chang HY, et al. Cryptic activation of an Irf8 enhancer governs cDC1 fate specification. Nature Immunology. PMID 31406378 DOI: 10.1038/S41590-019-0450-X |
0.365 |
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| 2019 |
Bagadia P, Huang X, Liu TT, Durai V, Grajales-Reyes GE, Nitschké M, Modrusan Z, Granja JM, Satpathy AT, Briseño CG, Gargaro M, Iwata A, Kim S, Chang HY, Shaw AS, et al. An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development. Nature Immunology. PMID 31406377 DOI: 10.1038/S41590-019-0449-3 |
0.39 |
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| 2019 |
Satpathy AT, Granja JM, Yost KE, Qi Y, Meschi F, McDermott GP, Olsen BN, Mumbach MR, Pierce SE, Corces MR, Shah P, Bell JC, Jhutty D, Nemec CM, Wang J, ... ... Chang HY, et al. Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion. Nature Biotechnology. 37: 925-936. PMID 31375813 DOI: 10.1038/S41587-019-0206-Z |
0.797 |
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| 2019 |
Yost KE, Satpathy AT, Wells DK, Qi Y, Wang C, Kageyama R, McNamara KL, Granja JM, Sarin KY, Brown RA, Gupta RK, Curtis C, Bucktrout SL, Davis MM, Chang ALS, ... Chang HY, et al. Clonal replacement of tumor-specific T cells following PD-1 blockade. Nature Medicine. PMID 31359002 DOI: 10.1038/S41591-019-0522-3 |
0.303 |
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| 2019 |
Ghosh RP, Shi Q, Yang L, Reddick MP, Nikitina T, Zhurkin VB, Fordyce P, Stasevich TJ, Chang HY, Greenleaf WJ, Liphardt JT. Satb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense regions. Nature Communications. 10: 3221. PMID 31324780 DOI: 10.1038/S41467-019-11118-8 |
0.308 |
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| 2019 |
Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, ... ... Chang HY, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. PMID 31316208 DOI: 10.1038/S41586-019-1406-X |
0.704 |
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| 2019 |
Fazal FM, Han S, Parker KR, Kaewsapsak P, Xu J, Boettiger AN, Chang HY, Ting AY. Atlas of Subcellular RNA Localization Revealed by APEX-Seq. Cell. PMID 31230715 DOI: 10.1016/J.Cell.2019.05.027 |
0.807 |
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| 2019 |
Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, ... ... Chang HY, et al. HiChIRP reveals RNA-associated chromosome conformation. Nature Methods. PMID 31133759 DOI: 10.1038/S41592-019-0407-X |
0.452 |
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| 2019 |
Xu J, Nuno K, Litzenburger UM, Qi Y, Corces MR, Majeti R, Chang HY. Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA. Elife. 8. PMID 30958261 DOI: 10.7554/Elife.45105 |
0.569 |
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| 2019 |
Sun L, Fazal FM, Li P, Broughton JP, Lee B, Tang L, Huang W, Kool ET, Chang HY, Zhang QC. RNA structure maps across mammalian cellular compartments. Nature Structural & Molecular Biology. PMID 30886404 DOI: 10.1038/S41594-019-0200-7 |
0.823 |
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| 2019 |
Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. PMID 30709738 DOI: 10.1016/J.Immuni.2018.12.016 |
0.361 |
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| 2019 |
Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, ... ... Chang HY, et al. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. Cell Stem Cell. PMID 30686763 DOI: 10.1016/J.Stem.2018.12.012 |
0.345 |
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| 2019 |
Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 8. PMID 30644360 DOI: 10.7554/Elife.40197 |
0.313 |
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| 2019 |
Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, ... ... Chang HY, et al. The novel lncRNA is pro-neurogenic and mutated in human neurodevelopmental disorders. Elife. 8. PMID 30628890 DOI: 10.7554/Elife.41770 |
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| 2019 |
Xu J, Nuno K, Litzenburger UM, Qi Y, Corces MR, Majeti R, Chang HY. Author response: Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA Elife. DOI: 10.7554/Elife.45105.033 |
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| 2019 |
Mumbach M, Granja J, Flynn R, Roake C, Satpathy A, Rubin A, Qi Y, Jiang Z, Shams S, Louie B, Guo J, Gennert D, Corces MR, Khavari P, Atianand M, ... ... Chang H, et al. HiChIRP: RNA-centric chromatin conformation Protocol Exchange. DOI: 10.1038/Protex.2019.032 |
0.4 |
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| 2019 |
Ramanathan M, Rubin A, Parker K, Satpathy A, Greenleaf W, Chang H, Khavari P. 366 Unraveling keratinocyte gene regulatory networks with single-cell cripsr screening and epigenomic profiling Journal of Investigative Dermatology. 139: S63. DOI: 10.1016/J.Jid.2019.03.442 |
0.302 |
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| 2019 |
Simonetta F, Maas-Bauer K, Hirai T, Wenokur A, Fazal FM, Kambham N, Ribado J, Mavers M, Baker J, Bhatt AS, Chang HY, Negrin RS. Distinct Immune Regulatory Potential of Invariant Natural Killer T (iNKT) Cell Subsets: iNKT2 and iNKT17, but Not iNKT1, Protect from Graft-Versus-Host-Disease Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.683 |
0.767 |
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| 2018 |
Rubin AJ, Parker KR, Satpathy AT, Qi Y, Wu B, Ong AJ, Mumbach MR, Ji AL, Kim DS, Cho SW, Zarnegar BJ, Greenleaf WJ, Chang HY, Khavari PA. Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell. PMID 30580963 DOI: 10.1016/J.Cell.2018.11.022 |
0.45 |
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| 2018 |
Lu Z, Chang HY. The RNA Base-Pairing Problem and Base-Pairing Solutions. Cold Spring Harbor Perspectives in Biology. 10. PMID 30510063 DOI: 10.1101/Cshperspect.A034926 |
0.561 |
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| 2018 |
Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, et al. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment. Nature Genetics. PMID 30397335 DOI: 10.1038/S41588-018-0263-0 |
0.347 |
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| 2018 |
Chen X, Litzenburger UM, Wei Y, Schep AN, LaGory EL, Choudhry H, Giaccia AJ, Greenleaf WJ, Chang HY. Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. Nature Communications. 9: 4590. PMID 30389926 DOI: 10.1038/S41467-018-07115-Y |
0.707 |
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| 2018 |
Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, ... ... Chang HY, et al. The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.). 362. PMID 30361341 DOI: 10.1126/Science.Aav1898 |
0.55 |
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| 2018 |
Ransom RC, Carter AC, Salhotra A, Leavitt T, Marecic O, Murphy MP, Lopez ML, Wei Y, Marshall CD, Shen EZ, Jones RE, Sharir A, Klein OD, Chan CKF, Wan DC, ... Chang HY, et al. Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration. Nature. PMID 30356216 DOI: 10.1038/S41586-018-0650-9 |
0.328 |
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| 2018 |
Jeng MY, Mumbach MR, Granja JM, Satpathy AT, Chang HY, Chang ALS. Enhancer connectome nominates target genes of inherited risk variants from inflammatory skin disorders. The Journal of Investigative Dermatology. PMID 30315781 DOI: 10.1016/J.Jid.2018.09.011 |
0.368 |
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| 2018 |
Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, ... ... Chang HY, et al. Identification of the Human Skeletal Stem Cell. Cell. 175: 43-56.e21. PMID 30241615 DOI: 10.1016/J.Cell.2018.07.029 |
0.572 |
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| 2018 |
Chu C, Chang HY. ChIRP-MS: RNA-Directed Proteomic Discovery. Methods in Molecular Biology (Clifton, N.J.). 1861: 37-45. PMID 30218357 DOI: 10.1007/978-1-4939-8766-5_3 |
0.392 |
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| 2018 |
Arda HE, Tsai J, Rosli YR, Giresi P, Bottino R, Greenleaf WJ, Chang HY, Kim SK. A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas. Cell Systems. PMID 30145115 DOI: 10.1016/J.Cels.2018.07.007 |
0.352 |
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| 2018 |
Gate RE, Cheng CS, Aiden AP, Siba A, Tabaka M, Lituiev D, Machol I, Gordon MG, Subramaniam M, Shamim M, Hougen KL, Wortman I, Huang SC, Durand NC, Feng T, ... ... Chang HY, et al. Genetic determinants of co-accessible chromatin regions in activated T cells across humans. Nature Genetics. PMID 29988122 DOI: 10.1038/S41588-018-0156-2 |
0.382 |
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| 2018 |
Duren Z, Chen X, Zamanighomi M, Zeng W, Satpathy AT, Chang HY, Wang Y, Wong WH. Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987051 DOI: 10.1073/Pnas.1805681115 |
0.347 |
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| 2018 |
Chen L, Roake CM, Freund A, Batista PJ, Tian S, Yin YA, Gajera CR, Lin S, Lee B, Pech MF, Venteicher AS, Das R, Chang HY, Artandi SE. An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1. Cell. PMID 29804836 DOI: 10.1016/J.Cell.2018.04.039 |
0.717 |
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| 2018 |
Satpathy AT, Brown RA, Gomulia E, Briseño CG, Mumbach MR, Pan Z, Murphy KM, Natkunam Y, Chang HY, Kim J. Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 29743654 DOI: 10.1038/S41379-018-0052-4 |
0.331 |
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| 2018 |
Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, ... ... Chang HY, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. PMID 29731168 DOI: 10.1016/J.Cell.2018.03.068 |
0.412 |
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| 2018 |
Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ. Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation. Cell. PMID 29706549 DOI: 10.1016/J.Cell.2018.03.074 |
0.632 |
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| 2018 |
Wang KC, Chang HY. Epigenomics: Technologies and Applications. Circulation Research. 122: 1191-1199. PMID 29700067 DOI: 10.1161/Circresaha.118.310998 |
0.504 |
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| 2018 |
Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, ... ... Chang HY, et al. Transcript-indexed ATAC-seq for precision immune profiling. Nature Medicine. PMID 29686426 DOI: 10.1038/S41591-018-0008-8 |
0.304 |
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| 2018 |
Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. PMID 29364875 DOI: 10.1038/Nature25449 |
0.426 |
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| 2018 |
Koh AS, Miller EL, Buenrostro JD, Moskowitz DM, Wang J, Greenleaf WJ, Chang HY, Crabtree GR. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nature Immunology. PMID 29335648 DOI: 10.1038/S41590-017-0032-8 |
0.335 |
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| 2018 |
Maas-Bauer K, Simonetta F, Hirai T, Wenokur A, Fazal F, Kambham N, Ribado J, Mavers M, Baker J, Bhatt AS, Chang HY, Negrin RS. Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential Blood. 132: 475-475. DOI: 10.1182/Blood-2018-99-113673 |
0.772 |
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| 2018 |
Lynn RC, Weber EW, Gennert D, Sotillo E, Jones R, Xu P, Satpathy A, Chang HY, Mackall CL. Abstract LB-112: Engineering AP1 to combat CAR T cell exhaustion Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-112 |
0.328 |
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| 2018 |
Chang HY. Abstract PL05-01: Personal regulome navigation Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-Pl05-01 |
0.415 |
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| 2018 |
Kim D, Risca V, Chappell J, Shi M, Zhao Z, Jung N, Chang H, Snyder M, Greenleaf W, Kundaje A, Khavari P. 795 Decoding regulatory sequence across skin differentiation with deep learning Journal of Investigative Dermatology. 138: S135. DOI: 10.1016/J.Jid.2018.03.805 |
0.392 |
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| 2018 |
Lee MY, Chen X, Gustavsson A, Chang HY, Moerner W. In Situ Imaging of Spatial Organization of Accessible Chromatin at the Nanoscale with ATAC-see and Single-Molecule Super-Resolution Fluorescence Microscopy Biophysical Journal. 114: 539a. DOI: 10.1016/J.Bpj.2017.11.2944 |
0.646 |
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| 2017 |
Chen YG, Chang HY. LncRNA Seduction of GOT2 Goes Viral. Immunity. 47: 1021-1023. PMID 29262346 DOI: 10.1016/J.Immuni.2017.12.006 |
0.343 |
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| 2017 |
Carter AC, Chang HY, Church G, Dombkowski A, Ecker JR, Gil E, Giresi PG, Greely H, Greenleaf WJ, Hacohen N, He C, Hill D, Ko J, Kohane I, Kundaje A, et al. Challenges and recommendations for epigenomics in precision health. Nature Biotechnology. 35: 1128-1132. PMID 29220033 DOI: 10.1038/Nbt.4030 |
0.344 |
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| 2017 |
Corces MR, Chang HY, Majeti R. Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia. Frontiers in Oncology. 7: 263. PMID 29164062 DOI: 10.3389/Fonc.2017.00263 |
0.558 |
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| 2017 |
Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT. The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 6. PMID 29087293 DOI: 10.7554/Elife.26116 |
0.732 |
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| 2017 |
Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, ... Chang HY, et al. Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons. Cell Reports. 20: 3236-3247. PMID 28954238 DOI: 10.1016/J.Celrep.2017.09.011 |
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| 2017 |
Lu Z, Carter AC, Chang HY. Mechanistic insights in X-chromosome inactivation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28947655 DOI: 10.1098/Rstb.2016.0356 |
0.525 |
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| 2017 |
Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Chang HY, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/Ng.3963 |
0.379 |
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| 2017 |
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Chang HY, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/Nature23875 |
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| 2017 |
Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, ... ... Chang HY, et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nature Methods. PMID 28846090 DOI: 10.1038/Nmeth.4396 |
0.459 |
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| 2017 |
Chen YG, Satpathy AT, Chang HY. Gene regulation in the immune system by long noncoding RNAs. Nature Immunology. 18: 962-972. PMID 28829444 DOI: 10.1038/Ni.3771 |
0.459 |
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| 2017 |
Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, ... ... Chang HY, et al. Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation. Nature Genetics. PMID 28805829 DOI: 10.1038/Ng.3935 |
0.494 |
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| 2017 |
Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, ... Chang HY, et al. m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways. Nature. PMID 28792938 DOI: 10.1038/Nature23450 |
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| 2017 |
Liu Q, Jiang C, Xu J, Zhao M, Van Bortle K, Cheng X, Wang G, Chang HY, Wu JC, Snyder MP. Genome-Wide Temporal Profiling of Transcriptome and Open-Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs. Circulation Research. PMID 28663367 DOI: 10.1161/Circresaha.116.310456 |
0.509 |
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| 2017 |
Wang KC, Chang HY. Transcription coactivator and lncRNA duet evoke Hox genes. Plos Genetics. 13: e1006797. PMID 28662057 DOI: 10.1371/Journal.Pgen.1006797 |
0.553 |
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| 2017 |
Chen YG, Kim MV, Chen X, Batista PJ, Aoyama S, Wilusz JE, Iwasaki A, Chang HY. Sensing Self and Foreign Circular RNAs by Intron Identity. Molecular Cell. PMID 28625551 DOI: 10.1016/J.Molcel.2017.05.022 |
0.818 |
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| 2017 |
Qu K, Zaba LC, Satpathy AT, Giresi PG, Li R, Jin Y, Armstrong R, Jin C, Schmitt N, Rahbar Z, Ueno H, Greenleaf WJ, Kim YH, Chang HY. Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors. Cancer Cell. PMID 28625481 DOI: 10.1016/J.Ccell.2017.05.008 |
0.331 |
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| 2017 |
Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell. 169: 1051-1065.e18. PMID 28575669 DOI: 10.1016/J.Cell.2017.05.022 |
0.38 |
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| 2017 |
Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, ... ... Chang HY, et al. Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. Nature Medicine. PMID 28288111 DOI: 10.1038/Nm.4309 |
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| 2017 |
Schmitt AM, Chang HY. Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. Cold Spring Harbor Perspectives in Medicine. PMID 28193769 DOI: 10.1101/Cshperspect.A026492 |
0.735 |
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| 2017 |
Litzenburger UM, Buenrostro JD, Wu B, Shen Y, Sheffield NC, Kathiria A, Greenleaf WJ, Chang HY. Single-cell epigenomic variability reveals functional cancer heterogeneity. Genome Biology. 18: 15. PMID 28118844 DOI: 10.1186/S13059-016-1133-7 |
0.323 |
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| 2017 |
Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY. Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells. Nature Genetics. PMID 28112738 DOI: 10.1038/Ng.3769 |
0.371 |
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| 2017 |
Bailey AS, Batista PJ, Gold RS, Chen YG, Rooij DGd, Chang HY, Fuller MT. Author response: The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline Elife. DOI: 10.7554/Elife.26116.050 |
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| 2017 |
Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, ... ... Chang HY, et al. Omni-ATAC-seq: Improved ATAC-seq protocol Protocol Exchange. DOI: 10.1038/Protex.2017.096 |
0.432 |
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| 2017 |
Lopez-Pajares V, Rubin A, Barajas B, Furlan-Magaril M, Mumbach M, Greenleaf W, Kundaje A, Snyder M, Chang H, Fraser P, Khavari P. 464 Dynamic and stable enhancer-promoter contacts regulate epidermal terminal differentiation Journal of Investigative Dermatology. 137: S80. DOI: 10.1016/J.Jid.2017.02.483 |
0.42 |
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| 2017 |
Moore AL, Marshall CD, Litzenburger U, Barnes L, Ransom RC, Hu M, Leavitt T, Chang HY, Longaker MT. Epigenetic Analysis of Scar Forming Fibroblasts Reveals Key Differences in Genes Associated with Fibrosis Journal of the American College of Surgeons. 225: S200-S201. DOI: 10.1016/J.Jamcollsurg.2017.07.460 |
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| 2016 |
Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science (New York, N.Y.). PMID 27980086 DOI: 10.1126/Science.Aah7111 |
0.456 |
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| 2016 |
Lee B, Flynn RA, Kadina A, Guo JK, Kool ET, Chang HY. Comparison of SHAPE Reagents for Mapping RNA Structures Inside Living Cells. Rna (New York, N.Y.). PMID 27879433 DOI: 10.1261/Rna.058784.116 |
0.388 |
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| 2016 |
Xu J, Spitale RC, Guan L, Flynn RA, Torre EA, Li R, Raber I, Qu K, Kern D, Knaggs HE, Chang HY, Chang AL. Novel Gene Expression Profile of Women with Intrinsic Skin Youthfulness by Whole Transcriptome Sequencing. Plos One. 11: e0165913. PMID 27829007 DOI: 10.1371/Journal.Pone.0165913 |
0.614 |
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| 2016 |
Chen X, Shen Y, Draper W, Buenrostro JD, Litzenburger U, Cho SW, Satpathy AT, Carter AC, Ghosh RP, East-Seletsky A, Doudna JA, Greenleaf WJ, Liphardt JT, Chang HY. ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing. Nature Methods. PMID 27749837 DOI: 10.1038/Nmeth.4031 |
0.708 |
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| 2016 |
Fazal FM, Chang HY. lncRNA Structure: Message to the Heart. Molecular Cell. 64: 1-2. PMID 27716479 DOI: 10.1016/J.Molcel.2016.09.030 |
0.775 |
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| 2016 |
Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. An inducible long noncoding RNA amplifies DNA damage signaling. Nature Genetics. PMID 27668660 DOI: 10.1038/Ng.3673 |
0.7 |
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| 2016 |
Chu C, Chang HY. Understanding RNA-Chromatin Interactions Using Chromatin Isolation by RNA Purification (ChIRP). Methods in Molecular Biology (Clifton, N.J.). 1480: 115-23. PMID 27659979 DOI: 10.1007/978-1-4939-6380-5_10 |
0.431 |
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| 2016 |
Corces MR, Buenrostro JD, Wu B, Greenside PG, Chan SM, Koenig JL, Snyder MP, Pritchard JK, Kundaje A, Greenleaf WJ, Majeti R, Chang HY. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nature Genetics. PMID 27526324 DOI: 10.1038/Ng.3646 |
0.671 |
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| 2016 |
Wang K, Lee CS, Marinkovich MP, Chang HY, Oro AE, Khavari PA. Factors That May Promote an Effective Local Research Environment. The Journal of Investigative Dermatology. 136: 1529-31. PMID 27450496 DOI: 10.1016/J.Jid.2016.04.015 |
0.452 |
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| 2016 |
Giorgetti L, Lajoie BR, Carter AC, Attia M, Zhan Y, Xu J, Chen CJ, Kaplan N, Chang HY, Heard E, Dekker J. Structural organization of the inactive X chromosome in the mouse. Nature. PMID 27437574 DOI: 10.1038/Nature18589 |
0.364 |
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| 2016 |
Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, et al. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 165: 1672-85. PMID 27315481 DOI: 10.1016/J.Cell.2016.05.075 |
0.406 |
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| 2016 |
Sadik H, Korangath P, Nguyen N, Győrffy B, Kumar R, Hedayati M, Teo WW, Park S, Panday H, Gonzalez Munoz T, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese TL, ... Chang HY, et al. HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells. Cancer Research. PMID 27302171 DOI: 10.1158/0008-5472.Can-16-0774 |
0.337 |
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| 2016 |
Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. PMID 27180905 DOI: 10.1016/J.Cell.2016.04.028 |
0.704 |
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| 2016 |
Arda HE, Li L, Tsai J, Torre EA, Rosli Y, Peiris H, Spitale RC, Dai C, Gu X, Qu K, Wang P, Wang J, Grompe M, Scharfmann R, Snyder MS, ... ... Chang HY, et al. Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function. Cell Metabolism. PMID 27133132 DOI: 10.1016/J.Cmet.2016.04.002 |
0.679 |
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| 2016 |
Zarnegar BJ, Flynn RA, Shen Y, Do BT, Chang HY, Khavari PA. irCLIP platform for efficient characterization of protein-RNA interactions. Nature Methods. PMID 27111506 DOI: 10.1038/Nmeth.3840 |
0.388 |
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| 2016 |
Ma Q, Chang HY. Single-cell profiling of lncRNAs in the developing human brain. Genome Biology. 17: 68. PMID 27079200 DOI: 10.1186/S13059-016-0933-0 |
0.399 |
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| 2016 |
Schmitt AM, Chang HY. Long Noncoding RNAs in Cancer Pathways. Cancer Cell. 29: 452-63. PMID 27070700 DOI: 10.1016/J.Ccell.2016.03.010 |
0.732 |
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| 2016 |
Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... ... Chang HY, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/J.Molcel.2016.03.013 |
0.422 |
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| 2016 |
Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, ... ... Chang HY, et al. Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget. 7: 28169-82. PMID 27058758 DOI: 10.18632/Oncotarget.8612 |
0.426 |
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| 2016 |
Lu Z, Chang HY. Decoding the RNA structurome. Current Opinion in Structural Biology. 36: 142-148. PMID 26923056 DOI: 10.1016/J.Sbi.2016.01.007 |
0.568 |
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| 2016 |
He C, Hu H, Wilson KD, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC. Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart. Circulation. Cardiovascular Genetics. PMID 26896382 DOI: 10.1161/Circgenetics.115.001264 |
0.408 |
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| 2016 |
Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. 7SK-BAF axis controls pervasive transcription at enhancers. Nature Structural & Molecular Biology. PMID 26878240 DOI: 10.1038/Nsmb.3176 |
0.441 |
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| 2016 |
Lee Y, Shin JH, Longmire M, Wang H, Kohrt HE, Chang HY, Sunwoo JB. CD44+ cells in head and neck squamous cell carcinoma suppress T cell-mediated immunity by selective constitutive and inducible expression of PD-L1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26864211 DOI: 10.1158/1078-0432.Ccr-15-2665 |
0.303 |
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| 2016 |
Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26789242 DOI: 10.1038/Nature16968 |
0.309 |
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| 2016 |
Quinn JJ, Zhang QC, Georgiev P, Ilik IA, Akhtar A, Chang HY. Rapid evolutionary turnover underlies conserved lncRNA-genome interactions. Genes & Development. 30: 191-207. PMID 26773003 DOI: 10.1101/Gad.272187.115 |
0.635 |
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| 2016 |
Flynn RA, Zhang QC, Spitale RC, Lee B, Mumbach MR, Chang HY. Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE. Nature Protocols. 11: 273-90. PMID 26766114 DOI: 10.1038/Nprot.2016.011 |
0.754 |
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| 2016 |
Wan Y, Qu K, Ouyang Z, Chang HY. Genome-Wide Probing of RNA Structures In Vitro Using Nucleases and Deep Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1361: 141-60. PMID 26483021 DOI: 10.1007/978-1-4939-3079-1_9 |
0.648 |
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| 2016 |
Chang HY. Abstract IA02: Genome regulation by long noncoding RNAs Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Ia02 |
0.469 |
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| 2016 |
Liu S, Horlbeck M, Cho SW, Birk H, Malatesta M, He D, Villalta J, Cho M, Chen Y, Mandegar M, Olvera M, Conklin B, Chang H, Weissman J, Lim D. GENT-49. SYSTEMATIC IDENTIFICATION OF ESSENTIAL LONG NON-CODING RNA GENES IN GLIOBLASTOMA Neuro-Oncology. 18: vi84-vi85. DOI: 10.1093/Neuonc/Now212.354 |
0.407 |
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| 2015 |
Bao X, Rubin AJ, Qu K, Zhang J, Giresi PG, Chang HY, Khavari PA. A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63. Genome Biology. 16: 284. PMID 26683334 DOI: 10.1186/S13059-015-0840-9 |
0.333 |
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| 2015 |
Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo FW, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26675721 DOI: 10.1038/Nature16193 |
0.45 |
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| 2015 |
Quinn JJ, Chang HY. Unique features of long non-coding RNA biogenesis and function. Nature Reviews. Genetics. 17: 47-62. PMID 26666209 DOI: 10.1038/Nrg.2015.10 |
0.412 |
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| 2015 |
Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, ... ... Chang HY, et al. The histone chaperone CAF-1 safeguards somatic cell identity. Nature. 528: 218-224. PMID 26659182 DOI: 10.1038/Nature15749 |
0.63 |
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| 2015 |
Carlson HL, Quinn JJ, Yang YW, Thornburg CK, Chang HY, Stadler HS. LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes. Plos Genetics. 11: e1005680. PMID 26633036 DOI: 10.1371/Journal.Pgen.1005680 |
0.436 |
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| 2015 |
Mazumdar C, Shen Y, Xavy S, Zhao F, Reinisch A, Li R, Corces MR, Flynn RA, Buenrostro JD, Chan SM, Thomas D, Koenig JL, Hong WJ, Chang HY, Majeti R. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell. PMID 26607380 DOI: 10.1182/Blood.V126.23.841.841 |
0.592 |
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| 2015 |
Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Erratum: Structural imprints in vivo decode RNA regulatory mechanisms. Nature. PMID 26416736 DOI: 10.1038/Nature15717 |
0.785 |
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| 2015 |
Qu K, Zaba LC, Giresi PG, Li R, Longmire M, Kim YH, Greenleaf WJ, Chang HY. Individuality and variation of personal regulomes in primary human T cells. Cell Systems. 1: 51-61. PMID 26251845 DOI: 10.1016/J.Cels.2015.06.003 |
0.356 |
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| 2015 |
Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Correction to "Structure and Thermodynamics of N(6)-Methyladenosine in RNA: A Spring-Loaded Base Modification". Journal of the American Chemical Society. PMID 26087989 DOI: 10.1021/Jacs.5B05858 |
0.687 |
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| 2015 |
Buenrostro JD, Wu B, Litzenburger UM, Ruff D, Gonzales ML, Snyder MP, Chang HY, Greenleaf WJ. Single-cell chromatin accessibility reveals principles of regulatory variation. Nature. 523: 486-90. PMID 26083756 DOI: 10.1038/Nature14590 |
0.506 |
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| 2015 |
Satpathy AT, Chang HY. Long noncoding RNA in hematopoiesis and immunity. Immunity. 42: 792-804. PMID 25992856 DOI: 10.1016/J.Immuni.2015.05.004 |
0.469 |
|
| 2015 |
Grow EJ, Flynn RA, Chavez SL, Bayless NL, Wossidlo M, Wesche DJ, Martin L, Ware CB, Blish CA, Chang HY, Pera RA, Wysocka J. Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells. Nature. 522: 221-5. PMID 25896322 DOI: 10.1038/Nature14308 |
0.368 |
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| 2015 |
Chu C, Zhang QC, da Rocha ST, Flynn RA, Bharadwaj M, Calabrese JM, Magnuson T, Heard E, Chang HY. Systematic discovery of Xist RNA binding proteins. Cell. 161: 404-16. PMID 25843628 DOI: 10.1016/J.Cell.2015.03.025 |
0.636 |
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| 2015 |
Chang H, Replogle JM, Vather N, Tsao-Wu M, Mistry R, Liu JM. A cis-regulatory antisense RNA represses translation in Vibrio cholerae through extensive complementarity and proximity to the target locus. Rna Biology. 12: 136-48. PMID 25826566 DOI: 10.1080/15476286.2015.1017203 |
0.377 |
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| 2015 |
Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Structural imprints in vivo decode RNA regulatory mechanisms. Nature. 519: 486-90. PMID 25799993 DOI: 10.1038/Nature14263 |
0.827 |
|
| 2015 |
Cho SW, Chang HY. Genomics: CRISPR engineering turns on genes. Nature. 517: 560-2. PMID 25631441 DOI: 10.1038/517560A |
0.373 |
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| 2015 |
Corley M, Solem A, Qu K, Chang HY, Laederach A. Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark. Nucleic Acids Research. 43: 1859-68. PMID 25618847 DOI: 10.1093/Nar/Gkv010 |
0.387 |
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| 2015 |
Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification. Journal of the American Chemical Society. 137: 2107-15. PMID 25611135 DOI: 10.1021/Ja513080V |
0.708 |
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| 2015 |
Chu C, Spitale RC, Chang HY. Technologies to probe functions and mechanisms of long noncoding RNAs. Nature Structural & Molecular Biology. 22: 29-35. PMID 25565030 DOI: 10.1038/Nsmb.2921 |
0.67 |
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| 2015 |
Buenrostro JD, Wu B, Chang HY, Greenleaf WJ. ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 109: 21.29.1-9. PMID 25559105 DOI: 10.1002/0471142727.Mb2129S109 |
0.317 |
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| 2015 |
Quinn JJ, Chang HY. In situ dissection of RNA functional subunits by domain-specific chromatin isolation by RNA purification (dChIRP). Methods in Molecular Biology (Clifton, N.J.). 1262: 199-213. PMID 25555583 DOI: 10.1007/978-1-4939-2253-6_12 |
0.41 |
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| 2015 |
Calo E, Flynn RA, Martin L, Spitale RC, Chang HY, Wysocka J. RNA helicase DDX21 coordinates transcription and ribosomal RNA processing. Nature. 518: 249-53. PMID 25470060 DOI: 10.1038/Nature13923 |
0.696 |
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| 2015 |
Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Dissecting noncoding and pathogen RNA-protein interactomes. Rna (New York, N.Y.). 21: 135-43. PMID 25411354 DOI: 10.1261/Rna.047803.114 |
0.677 |
|
| 2014 |
Paik KJ, Qu K, Hsueh B, Torre EA, Flynn RA, Chung MT, Spencley A, Wang KC, Wu JC, Longaker MT, Chang HY, Wan DC. Abstract 158: Identification of BMP-Responsive Long Noncoding RNAs in Pluripotent Cells. Plastic and Reconstructive Surgery. 133: 174. PMID 25942268 DOI: 10.1097/01.Prs.0000444987.90678.B2 |
0.589 |
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| 2014 |
Batista PJ, Molinie B, Wang J, Qu K, Zhang J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, Carter AC, Flynn RA, Zhou C, Lim KS, Dedon P, ... ... Chang HY, et al. m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 15: 707-19. PMID 25456834 DOI: 10.1016/J.Stem.2014.09.019 |
0.713 |
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| 2014 |
Benitez CM, Qu K, Sugiyama T, Pauerstein PT, Liu Y, Tsai J, Gu X, Ghodasara A, Arda HE, Zhang J, Dekker JD, Tucker HO, Chang HY, Kim SK. An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development. Plos Genetics. 10: e1004645. PMID 25330008 DOI: 10.1371/Journal.Pgen.1004645 |
0.398 |
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| 2014 |
Quinn JJ, Chang HY. RNA switch at enhancers. Nature Genetics. 46: 929-31. PMID 25162802 DOI: 10.1038/Ng.3074 |
0.414 |
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| 2014 |
Spitale RC, Flynn RA, Torre EA, Kool ET, Chang HY. RNA structural analysis by evolving SHAPE chemistry. Wiley Interdisciplinary Reviews. Rna. 5: 867-81. PMID 25132067 DOI: 10.1002/Wrna.1253 |
0.682 |
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| 2014 |
Li L, Chang HY. Physiological roles of long noncoding RNAs: insight from knockout mice. Trends in Cell Biology. 24: 594-602. PMID 25022466 DOI: 10.1016/J.Tcb.2014.06.003 |
0.459 |
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| 2014 |
Quinn JJ, Ilik IA, Qu K, Georgiev P, Chu C, Akhtar A, Chang HY. Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification. Nature Biotechnology. 32: 933-40. PMID 24997788 DOI: 10.1038/Nbt.2943 |
0.429 |
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| 2014 |
Zheng GX, Do BT, Webster DE, Khavari PA, Chang HY. Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs. Nature Structural & Molecular Biology. 21: 585-90. PMID 24929436 DOI: 10.1038/Nsmb.2842 |
0.763 |
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| 2014 |
Flynn RA, Chang HY. Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell. 14: 752-61. PMID 24905165 DOI: 10.1016/J.Stem.2014.05.014 |
0.441 |
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| 2014 |
Buenrostro JD, Araya CL, Chircus LM, Layton CJ, Chang HY, Snyder MP, Greenleaf WJ. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nature Biotechnology. 32: 562-8. PMID 24727714 DOI: 10.1038/Nbt.2880 |
0.545 |
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| 2014 |
Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife. 3: e02046. PMID 24521543 DOI: 10.7554/Elife.02046 |
0.528 |
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| 2014 |
Wan Y, Qu K, Zhang QC, Flynn RA, Manor O, Ouyang Z, Zhang J, Spitale RC, Snyder MP, Segal E, Chang HY. Landscape and variation of RNA secondary structure across the human transcriptome. Nature. 505: 706-9. PMID 24476892 DOI: 10.1038/Nature12946 |
0.821 |
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| 2014 |
Mazumdar C, Li R, Buenrostro J, Chang HY, Majeti R. Cohesin Complex Mutations Impair Differentiation of Human Hematopoietic Stem and Progenitor Cells Blood. 124: 4785-4785. DOI: 10.1182/Blood.V124.21.4785.4785 |
0.343 |
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| 2014 |
Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of Native Chromatin for Fast and Sensitive Mulitmodal Analysis of Chromatin Architecture Biophysical Journal. 106: 77a. DOI: 10.1016/J.Bpj.2013.11.503 |
0.394 |
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| 2013 |
Harcourt EM, Ehrenschwender T, Batista PJ, Chang HY, Kool ET. Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA. Journal of the American Chemical Society. 135: 19079-82. PMID 24328136 DOI: 10.1021/Ja4105792 |
0.7 |
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| 2013 |
Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, ... ... Chang HY, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/J.Cell.2013.09.028 |
0.368 |
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| 2013 |
Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nature Methods. 10: 1213-8. PMID 24097267 DOI: 10.1038/Nmeth.2688 |
0.346 |
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| 2013 |
Li L, Liu B, Wapinski OL, Tsai MC, Qu K, Zhang J, Carlson JC, Lin M, Fang F, Gupta RA, Helms JA, Chang HY. Targeted disruption of Hotair leads to homeotic transformation and gene derepression. Cell Reports. 5: 3-12. PMID 24075995 DOI: 10.1016/J.Celrep.2013.09.003 |
0.417 |
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| 2013 |
Schmitt AM, Chang HY. Gene regulation: Long RNAs wire up cancer growth. Nature. 500: 536-7. PMID 23945584 DOI: 10.1038/Nature12548 |
0.701 |
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| 2013 |
Rapicavoli NA, Qu K, Zhang J, Mikhail M, Laberge RM, Chang HY. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics. Elife. 2: e00762. PMID 23898399 DOI: 10.7554/Elife.00762 |
0.332 |
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| 2013 |
Ilik IA, Quinn JJ, Georgiev P, Tavares-Cadete F, Maticzka D, Toscano S, Wan Y, Spitale RC, Luscombe N, Backofen R, Chang HY, Akhtar A. Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila. Molecular Cell. 51: 156-73. PMID 23870142 DOI: 10.1016/J.Molcel.2013.07.001 |
0.755 |
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| 2013 |
Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Research. 73: 5449-58. PMID 23832664 DOI: 10.1158/0008-5472.Can-13-1178 |
0.328 |
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| 2013 |
Wan Y, Qu K, Ouyang Z, Chang HY. Genome-wide mapping of RNA structure using nuclease digestion and high-throughput sequencing. Nature Protocols. 8: 849-69. PMID 23558785 DOI: 10.1038/Nprot.2013.045 |
0.647 |
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| 2013 |
Batista PJ, Chang HY. Long noncoding RNAs: cellular address codes in development and disease. Cell. 152: 1298-307. PMID 23498938 DOI: 10.1016/J.Cell.2013.02.012 |
0.716 |
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| 2013 |
Gomez JA, Wapinski OL, Yang YW, Bureau JF, Gopinath S, Monack DM, Chang HY, Brahic M, Kirkegaard K. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell. 152: 743-54. PMID 23415224 DOI: 10.1016/J.Cell.2013.01.015 |
0.67 |
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| 2013 |
Batista PJ, Chang HY. Cytotopic localization by long noncoding RNAs. Current Opinion in Cell Biology. 25: 195-9. PMID 23279909 DOI: 10.1016/J.Ceb.2012.12.001 |
0.74 |
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| 2013 |
Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, ... ... Chang HY, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 493: 231-5. PMID 23201690 DOI: 10.1038/Nature11661 |
0.821 |
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| 2013 |
Spitale RC, Crisalli P, Flynn RA, Torre EA, Kool ET, Chang HY. RNA SHAPE analysis in living cells. Nature Chemical Biology. 9: 18-20. PMID 23178934 DOI: 10.1038/Nchembio.1131 |
0.694 |
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| 2013 |
Ouyang Z, Snyder MP, Chang HY. SeqFold: genome-scale reconstruction of RNA secondary structure integrating high-throughput sequencing data. Genome Research. 23: 377-87. PMID 23064747 DOI: 10.1101/Gr.138545.112 |
0.534 |
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| 2013 |
Chang AL, Bitter PH, Qu K, Lin M, Rapicavoli NA, Chang HY. Rejuvenation of gene expression pattern of aged human skin by broadband light treatment: a pilot study. The Journal of Investigative Dermatology. 133: 394-402. PMID 22931923 DOI: 10.1038/Jid.2012.287 |
0.334 |
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| 2013 |
Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Author response: Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency Elife. DOI: 10.7554/Elife.02046.013 |
0.527 |
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| 2013 |
Chang HY. Abstract SY31-03: Genome regulation by long noncoding RNAs. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy31-03 |
0.485 |
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| 2013 |
Abignano G, Hermes H, Esteves F, Gillespie J, Chang HY, Jimenez SA, Emery P, Galdo FD. SAT0022 Palmoplantar specific long NCRNA hotair drives myofibroblasts specific signature in systemic sclerosis Annals of the Rheumatic Diseases. 71: 478-478. DOI: 10.1136/Annrheumdis-2012-Eular.2970 |
0.362 |
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| 2013 |
Schmitt A, Hung T, Flynn R, Payumo A, Peres-da-Silva A, Kenzelmann Broz D, Attardi L, Chen J, Chang H. Regulation of the DNA Damage Response by an Inducible Long Noncoding RNA International Journal of Radiation Oncology*Biology*Physics. 87: S19. DOI: 10.1016/J.Ijrobp.2013.06.055 |
0.701 |
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| 2012 |
Siprashvili Z, Webster DE, Kretz M, Johnston D, Rinn JL, Chang HY, Khavari PA. Identification of proteins binding coding and non-coding human RNAs using protein microarrays. Bmc Genomics. 13: 633. PMID 23157412 DOI: 10.1186/1471-2164-13-633 |
0.634 |
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| 2012 |
Martin L, Meier M, Lyons SM, Sit RV, Marzluff WF, Quake SR, Chang HY. Systematic reconstruction of RNA functional motifs with high-throughput microfluidics Nature Methods. 9: 1192-1194. PMID 23142872 DOI: 10.1038/Nmeth.2225 |
0.422 |
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| 2012 |
Chisholm KM, Wan Y, Li R, Montgomery KD, Chang HY, West RB. Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma. Plos One. 7: e47998. PMID 23133536 DOI: 10.1371/Journal.Pone.0047998 |
0.639 |
|
| 2012 |
Wan Y, Qu K, Ouyang Z, Kertesz M, Li J, Tibshirani R, Makino DL, Nutter RC, Segal E, Chang HY. Genome-wide measurement of RNA folding energies. Molecular Cell. 48: 169-81. PMID 22981864 DOI: 10.1016/J.Molcel.2012.08.008 |
0.656 |
|
| 2012 |
Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, et al. Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts. Blood. 120: 3288-97. PMID 22936659 DOI: 10.1182/Blood-2012-04-423061 |
0.45 |
|
| 2012 |
Brunner AL, Beck AH, Edris B, Sweeney RT, Zhu SX, Li R, Montgomery K, Varma S, Gilks T, Guo X, Foley JW, Witten DM, Giacomini CP, Flynn RA, Pollack JR, ... ... Chang HY, et al. Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers. Genome Biology. 13: R75. PMID 22929540 DOI: 10.1186/Gb-2012-13-8-R75 |
0.432 |
|
| 2012 |
Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, ... ... Chang HY, et al. The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discovery. 2: 638-51. PMID 22728437 DOI: 10.1158/2159-8290.Cd-12-0093 |
0.643 |
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| 2012 |
Rinn JL, Chang HY. Genome regulation by long noncoding RNAs. Annual Review of Biochemistry. 81: 145-66. PMID 22663078 DOI: 10.1182/Blood.V122.21.Sci-29.Sci-29 |
0.673 |
|
| 2012 |
Martin L, Chang HY. Uncovering the role of genomic "dark matter" in human disease. The Journal of Clinical Investigation. 122: 1589-95. PMID 22546862 DOI: 10.1172/Jci60020 |
0.407 |
|
| 2012 |
Chu C, Quinn J, Chang HY. Chromatin isolation by RNA purification (ChIRP). Journal of Visualized Experiments : Jove. PMID 22472705 DOI: 10.3791/3912 |
0.489 |
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| 2012 |
Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes & Development. 26: 338-43. PMID 22302877 DOI: 10.1101/Gad.182121.111 |
0.809 |
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| 2012 |
Wang P, McKnight KD, Wong DJ, Rodriguez RT, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang HY, Kim SK. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells and Development. 21: 2273-87. PMID 22236333 DOI: 10.1089/Scd.2011.0416 |
0.351 |
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| 2012 |
Flynn RA, Chang HY. Active chromatin and noncoding RNAs: an intimate relationship. Current Opinion in Genetics & Development. 22: 172-8. PMID 22154525 DOI: 10.1016/J.Gde.2011.11.002 |
0.438 |
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| 2012 |
Marques M, Nieves B, Chen R, Vaka D, Chan C, Zheng G, Chang H, Weissman I, Sweet-Cordero A. Abstract 1427: Signal rewiring induced by EWS/FLI-1 in mouse and human mesenchymal stem cells Cancer Research. 72: 1427-1427. DOI: 10.1158/1538-7445.Am2012-1427 |
0.755 |
|
| 2011 |
Chu C, Qu K, Zhong FL, Artandi SE, Chang HY. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Molecular Cell. 44: 667-78. PMID 21963238 DOI: 10.1016/J.Molcel.2011.08.027 |
0.465 |
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| 2011 |
Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell. 9: 374-82. PMID 21962918 DOI: 10.1016/J.Stem.2011.09.002 |
0.358 |
|
| 2011 |
Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Molecular Cell. 43: 904-14. PMID 21925379 DOI: 10.1016/J.Molcel.2011.08.018 |
0.57 |
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| 2011 |
Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Understanding the transcriptome through RNA structure. Nature Reviews. Genetics. 12: 641-55. PMID 21850044 DOI: 10.1038/Nrg3049 |
0.765 |
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| 2011 |
Alastalo TP, Li M, De Jesus Perez V, Pham D, Sawada H, Wang JK, Koskenvuo M, Wang L, Freeman BA, Chang HY, Rabinovitch M. Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival Journal of Clinical Investigation. 121: 3735-3746. PMID 21821917 DOI: 10.1172/Jci43382 |
0.316 |
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| 2011 |
Kawahara TLA, Rapicavoli NA, Wu AR, Qu K, Quake SR, Chang HY. Dynamic chromatin localization of sirt6 shapes stress- and aging-related transcriptional networks Plos Genetics. 7. PMID 21738489 DOI: 10.1371/Journal.Pgen.1002153 |
0.35 |
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| 2011 |
Chen Y, Wan B, Wang KC, Cao F, Yang Y, Protacio A, Dou Y, Chang HY, Lei M. Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Reports. 12: 797-803. PMID 21660059 DOI: 10.1038/Embor.2011.101 |
0.504 |
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| 2011 |
Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, ... ... Chang HY, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nature Genetics. 43: 621-9. PMID 21642992 DOI: 10.1038/Ng.848 |
0.484 |
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| 2011 |
Wapinski O, Chang HY. Long noncoding RNAs and human disease. Trends in Cell Biology. 21: 354-61. PMID 21550244 DOI: 10.1016/J.Tcb.2011.04.001 |
0.426 |
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| 2011 |
Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature. 472: 120-4. PMID 21423168 DOI: 10.1038/Nature09819 |
0.602 |
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| 2011 |
Spitale RC, Tsai MC, Chang HY. RNA templating the epigenome: long noncoding RNAs as molecular scaffolds. Epigenetics : Official Journal of the Dna Methylation Society. 6: 539-43. PMID 21393997 DOI: 10.4161/Epi.6.5.15221 |
0.681 |
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| 2011 |
Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Research. 71: 3-7. PMID 21199792 DOI: 10.1158/0008-5472.Can-10-2483 |
0.689 |
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| 2011 |
Wapinski O, Chang HY. Corrigendum: Long noncoding RNAs and human disease. [Trends in Cell Biology 21 (2011), 354-361] Trends in Cell Biology. 21: 561. DOI: 10.1016/J.Tcb.2011.08.004 |
0.349 |
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| 2010 |
Ouyang Z, Zheng GX, Chang HY. Noncoding RNA landmarks of pluripotency and reprogramming. Cell Stem Cell. 7: 649-50. PMID 21112559 DOI: 10.1016/J.Stem.2010.11.018 |
0.757 |
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| 2010 |
Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J. G1 arrest and differentiation can occur independently of Rb family function. The Journal of Cell Biology. 191: 809-25. PMID 21059851 DOI: 10.1083/Jcb.201003048 |
0.633 |
|
| 2010 |
Hung T, Chang HY. Long noncoding RNA in genome regulation: prospects and mechanisms. Rna Biology. 7: 582-5. PMID 20930520 DOI: 10.4161/Rna.7.5.13216 |
0.498 |
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| 2010 |
Wan Y, Chang HY. HOTAIR: Flight of noncoding RNAs in cancer metastasis. Cell Cycle (Georgetown, Tex.). 9: 3391-2. PMID 20864820 DOI: 10.4161/Cc.9.17.13122 |
0.671 |
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| 2010 |
Kertesz M, Wan Y, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E. Genome-wide measurement of RNA secondary structure in yeast. Nature. 467: 103-7. PMID 20811459 DOI: 10.1038/Nature09322 |
0.737 |
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| 2010 |
Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY. Long noncoding RNA as modular scaffold of histone modification complexes. Science (New York, N.Y.). 329: 689-93. PMID 20616235 DOI: 10.1126/Science.1192002 |
0.614 |
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| 2010 |
Tsai MC, Wang JK, Chang HY. Tumor suppression by the histone demethylase UTX. Cell Cycle (Georgetown, Tex.). 9: 2043-4. PMID 20505331 DOI: 10.4161/Cc.9.11.11845 |
0.431 |
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| 2010 |
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, ... ... Chang HY, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 464: 1071-6. PMID 20393566 DOI: 10.1038/Nature08975 |
0.712 |
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| 2010 |
Wang JK, Tsai MC, Poulin G, Adler AS, Chen S, Liu H, Shi Y, Chang HY. The histone demethylase UTX enables RB-dependent cell fate control. Genes & Development. 24: 327-32. PMID 20123895 DOI: 10.1101/Gad.1882610 |
0.686 |
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| 2010 |
Sargent JL, Milano A, Bhattacharyya S, Varga J, Connolly MK, Chang HY, Whitfield ML. A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity. The Journal of Investigative Dermatology. 130: 694-705. PMID 19812599 DOI: 10.1038/Jid.2009.318 |
0.307 |
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| 2010 |
Kertesz M, Wan Y, Mazor E, Rinn J, Nutter R, Chang H, Segal E. Probing RNA structure genome-wide using high throughput sequencing Nature Protocols. DOI: 10.1038/Nprot.2010.152 |
0.719 |
|
| 2009 |
Chang HY. Anatomic demarcation of cells: genes to patterns. Science (New York, N.Y.). 326: 1206-7. PMID 19965461 DOI: 10.1126/Science.1175686 |
0.378 |
|
| 2009 |
Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J, Chang HY, van de Rijn M, Shortliffe L, Weissman IL. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 14016-21. PMID 19666525 DOI: 10.1073/Pnas.0906549106 |
0.513 |
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| 2009 |
Mace KA, Restivo TE, Rinn JL, Paquet AC, Chang HY, Young DM, Boudreau NJ. HOXA3 modulates injury-induced mobilization and recruitment of bone marrow-derived cells. Stem Cells (Dayton, Ohio). 27: 1654-65. PMID 19544454 DOI: 10.1002/Stem.90 |
0.565 |
|
| 2009 |
Chang HY, Cuvier O, Dekker J. Gene dates, parties and galas. Symposium on Chromatin Dynamics and Higher Order Organization. Embo Reports. 10: 689-93. PMID 19525922 DOI: 10.1038/Embor.2009.136 |
0.344 |
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| 2009 |
Reuter JA, Ortiz-Urda S, Kretz M, Garcia J, Scholl FA, Pasmooij AM, Cassarino D, Chang HY, Khavari PA. Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell. 15: 477-88. PMID 19477427 DOI: 10.1016/J.Ccr.2009.04.002 |
0.334 |
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| 2009 |
Wang KC, Helms JA, Chang HY. Regeneration, repair and remembering identity: the three Rs of Hox gene expression. Trends in Cell Biology. 19: 268-75. PMID 19428253 DOI: 10.1016/J.Tcb.2009.03.007 |
0.594 |
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| 2009 |
Rando OJ, Chang HY. Genome-wide views of chromatin structure. Annual Review of Biochemistry. 78: 245-71. PMID 19317649 DOI: 10.1146/Annurev.Biochem.78.071107.134639 |
0.37 |
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| 2009 |
Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, Witten DM, Chang HY, Shurtleff SA, Downing JR, Cleary ML. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell. 4: 129-40. PMID 19200802 DOI: 10.1016/J.Stem.2008.11.015 |
0.584 |
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| 2009 |
Hung T, Binda O, Champagne KS, Kuo AJ, Johnson K, Chang HY, Simon MD, Kutateladze TG, Gozani O. ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Molecular Cell. 33: 248-56. PMID 19187765 DOI: 10.1016/J.Molcel.2008.12.016 |
0.304 |
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| 2009 |
Chung L, Fiorentino DF, Benbarak MJ, Adler AS, Mariano MM, Paniagua RT, Milano A, Connolly MK, Ratiner BD, Wiskocil RL, Whitfield ML, Chang HY, Robinson WH. Molecular framework for response to imatinib mesylate in systemic sclerosis. Arthritis and Rheumatism. 60: 584-91. PMID 19180499 DOI: 10.1002/Art.24221 |
0.618 |
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| 2009 |
Kawahara TL, Michishita E, Adler AS, Damian M, Berber E, Lin M, McCord RA, Ongaigui KC, Boxer LD, Chang HY, Chua KF. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell. 136: 62-74. PMID 19135889 DOI: 10.1016/J.Cell.2008.10.052 |
0.639 |
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| 2008 |
Sääf AM, Tengvall-Linder M, Chang HY, Adler AS, Wahlgren CF, Scheynius A, Nordenskjöld M, Bradley M. Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes. Plos One. 3: e4017. PMID 19107207 DOI: 10.1371/Journal.Pone.0004017 |
0.656 |
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| 2008 |
Wong DJ, Segal E, Chang HY. Stemness, cancer and cancer stem cells. Cell Cycle (Georgetown, Tex.). 7: 3622-4. PMID 19029796 DOI: 10.4161/Cc.7.23.7104 |
0.347 |
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| 2008 |
Nuyten DS, Hastie T, Chi JT, Chang HY, van de Vijver MJ. Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification. European Journal of Cancer (Oxford, England : 1990). 44: 2319-29. PMID 18715778 DOI: 10.1016/J.Ejca.2008.07.015 |
0.302 |
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| 2008 |
Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science (New York, N.Y.). 321: 843-7. PMID 18687966 DOI: 10.1126/Science.1159407 |
0.319 |
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| 2008 |
Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes & Development. 22: 1865-70. PMID 18628393 DOI: 10.1101/Gad.1673508 |
0.33 |
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| 2008 |
Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, Devoss JJ, Johannes KP, Lu W, Gardner J, Chang A, Bubulya P, Chang HY, Peterlin BM, Anderson MS. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. The Journal of Clinical Investigation. 118: 1712-26. PMID 18414681 DOI: 10.1172/Jci34523 |
0.549 |
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| 2008 |
Wong DJ, Liu H, Ridky TW, Cassarino D, Segal E, Chang HY. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell. 2: 333-44. PMID 18397753 DOI: 10.1016/J.Stem.2008.02.009 |
0.366 |
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| 2008 |
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 452: 492-6. PMID 18337721 DOI: 10.1038/Nature06736 |
0.318 |
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| 2008 |
Rinn JL, Wang JK, Liu H, Montgomery K, van de Rijn M, Chang HY. A systems biology approach to anatomic diversity of skin. The Journal of Investigative Dermatology. 128: 776-82. PMID 18337710 DOI: 10.1038/Sj.Jid.5700986 |
0.602 |
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| 2008 |
Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade. Cell Cycle (Georgetown, Tex.). 7: 556-9. PMID 18256548 DOI: 10.4161/Cc.7.5.5490 |
0.638 |
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| 2008 |
Sinha S, Adler AS, Field Y, Chang HY, Segal E. Systematic functional characterization of cis-regulatory motifs in human core promoters. Genome Research. 18: 477-88. PMID 18256240 DOI: 10.1101/Gr.6828808 |
0.673 |
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| 2008 |
Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY. A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes & Development. 22: 303-7. PMID 18245445 DOI: 10.1101/gad.1610508 |
0.546 |
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| 2008 |
Adler AS, Littlepage LE, Lin M, Kawahara TL, Wong DJ, Werb Z, Chang HY. CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression. Cancer Research. 68: 506-15. PMID 18199546 DOI: 10.1158/0008-5472.Can-07-3060 |
0.629 |
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| 2008 |
Wong DJ, Nuyten DS, Regev A, Lin M, Adler AS, Segal E, van de Vijver MJ, Chang HY. Revealing targeted therapy for human cancer by gene module maps. Cancer Research. 68: 369-78. PMID 18199530 DOI: 10.1158/0008-5472.Can-07-0382 |
0.667 |
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| 2007 |
Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E, Chang HY. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes & Development. 21: 3244-57. PMID 18055696 DOI: 10.1101/Gad.1588507 |
0.641 |
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| 2007 |
Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature. 449: 689-94. PMID 17851529 DOI: 10.1038/Nature06192 |
0.624 |
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| 2007 |
Chang HY, Cotsarelis G. Turning skin into embryonic stem cells. Nature Medicine. 13: 783-4. PMID 17618266 DOI: 10.1038/Nm0707-783 |
0.321 |
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| 2007 |
Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 129: 1311-23. PMID 17604720 DOI: 10.1016/J.Cell.2007.05.022 |
0.657 |
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| 2007 |
Liu H, Adler AS, Segal E, Chang HY. A transcriptional program mediating entry into cellular quiescence. Plos Genetics. 3: e91. PMID 17559306 DOI: 10.1371/Journal.Pgen.0030091 |
0.679 |
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| 2007 |
O'Geen H, Squazzo SL, Iyengar S, Blahnik K, Rinn JL, Chang HY, Green R, Farnham PJ. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. Plos Genetics. 3: e89. PMID 17542650 DOI: 10.1371/Journal.Pgen.0030089 |
0.622 |
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| 2007 |
Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nature Biotechnology. 25: 675-80. PMID 17515910 DOI: 10.1038/Nbt1306 |
0.643 |
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| 2006 |
Chang HY, Thomson JA, Chen X. Microarray analysis of stem cells and differentiation. Methods in Enzymology. 420: 225-54. PMID 17161699 DOI: 10.1016/S0076-6879(06)20010-7 |
0.39 |
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| 2006 |
DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Caspi R, Fong L, Anderson MS. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. The Journal of Experimental Medicine. 203: 2727-35. PMID 17116738 DOI: 10.1084/Jem.20061864 |
0.539 |
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| 2006 |
Nuyten DS, Kreike B, Hart AA, Chi JT, Sneddon JB, Wessels LF, Peterse HJ, Bartelink H, Brown PO, Chang HY, van de Vijver MJ. Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast Cancer Research : Bcr. 8: R62. PMID 17069664 DOI: 10.1186/Bcr1614 |
0.744 |
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| 2006 |
Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 103: 14842-7. PMID 17003113 DOI: 10.1073/Pnas.0606857103 |
0.778 |
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| 2006 |
Rinn JL, Bondre C, Gladstone HB, Brown PO, Chang HY. Anatomic demarcation by positional variation in fibroblast gene expression programs. Plos Genetics. 2: e119. PMID 16895450 DOI: 10.1371/Journal.Pgen.0020119 |
0.676 |
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| 2006 |
Ray S, Atkuri KR, Deb-Basu D, Adler AS, Chang HY, Herzenberg LA, Felsher DW. MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species. Cancer Research. 66: 6598-605. PMID 16818632 DOI: 10.1158/0008-5472.Can-05-3115 |
0.632 |
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| 2006 |
Adler AS, Chang HY. From description to causality: mechanisms of gene expression signatures in cancer. Cell Cycle (Georgetown, Tex.). 5: 1148-51. PMID 16721055 DOI: 10.4161/Cc.5.11.2798 |
0.671 |
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| 2006 |
Adler AS, Lin M, Horlings H, Nuyten DS, van de Vijver MJ, Chang HY. Genetic regulators of large-scale transcriptional signatures in cancer. Nature Genetics. 38: 421-30. PMID 16518402 DOI: 10.1038/Ng1752 |
0.666 |
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| 2006 |
DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Fong L, Anderson MS. CORRECTION Journal of Experimental Medicine. 204: 203-203. DOI: 10.1084/Jem.20061864121306C |
0.476 |
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| 2005 |
Wong DJ, Chang HY. Learning more from microarrays: insights from modules and networks. The Journal of Investigative Dermatology. 125: 175-82. PMID 16098025 DOI: 10.1111/J.0022-202X.2005.23827.X |
0.352 |
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| 2005 |
Tang J, Chang HY, Yang X. The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62. Febs Letters. 579: 2883-90. PMID 15878163 DOI: 10.1016/J.Febslet.2005.04.029 |
0.331 |
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| 2005 |
Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proceedings of the National Academy of Sciences of the United States of America. 102: 3738-43. PMID 15701700 DOI: 10.1073/Pnas.0409462102 |
0.754 |
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| 2005 |
Nuyten D, Chang H, Brown P, Vijver MVd. Reproducibility of molecular portraits in early stage breast cancer Breast Cancer Research. 7: 1-2. DOI: 10.1186/Bcr1156 |
0.436 |
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| 2004 |
Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. Plos Biology. 2: E7. PMID 14737219 DOI: 10.1371/Journal.Pbio.0020007 |
0.791 |
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| 2003 |
Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO. Endothelial cell diversity revealed by global expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 100: 10623-8. PMID 12963823 DOI: 10.1073/Pnas.1434429100 |
0.503 |
|
| 2003 |
Chi JT, Chang HY, Wang NN, Chang DS, Dunphy N, Brown PO. Genomewide view of gene silencing by small interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America. 100: 6343-6. PMID 12730368 DOI: 10.1073/Pnas.1037853100 |
0.614 |
|
| 2002 |
Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, Brown PO. Diversity, topographic differentiation, and positional memory in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 12877-82. PMID 12297622 DOI: 10.1073/Pnas.162488599 |
0.544 |
|
| 1999 |
Chang HY, Yang X, Baltimore D. Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 96: 1252-6. PMID 9990010 DOI: 10.1073/Pnas.96.4.1252 |
0.434 |
|
| 1998 |
Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science (New York, N.Y.). 281: 1860-3. PMID 9743501 DOI: 10.1126/Science.281.5384.1860 |
0.423 |
|
| 1998 |
Yang X, Chang HY, Baltimore D. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science (New York, N.Y.). 281: 1355-7. PMID 9721101 DOI: 10.1126/Science.281.5381.1355 |
0.451 |
|
| 1998 |
Yang X, Chang HY, Baltimore D. Autoproteolytic activation of pro-caspases by oligomerization. Molecular Cell. 1: 319-25. PMID 9659928 DOI: 10.1016/S1097-2765(00)80032-5 |
0.41 |
|
| 1997 |
Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 89: 1067-76. PMID 9215629 DOI: 10.1016/S0092-8674(00)80294-9 |
0.423 |
|
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