Laura Attardi - Publications

Stanford University, Palo Alto, CA 

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bowen ME, McClendon J, Long HK, Sorayya A, Van Nostrand JL, Wysocka J, Attardi LD. The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes. Developmental Cell. PMID 31178404 DOI: 10.1016/j.devcel.2019.05.015  0.36
2019 Jacobs SBR, Van Nostrand JL, Bowen ME, Baker JC, Attardi LD. Siva plays a critical role in mouse embryonic development. Cell Death and Differentiation. PMID 31164717 DOI: 10.1038/s41418-019-0358-x  0.36
2017 Van Nostrand JL, Bowen ME, Vogel H, Barna M, Attardi LD. The p53 family members have distinct roles during mammalian embryonic development. Cell Death and Differentiation. PMID 28211873 DOI: 10.1038/cdd.2016.128  0.36
2016 Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. An inducible long noncoding RNA amplifies DNA damage signaling. Nature Genetics. PMID 27668660 DOI: 10.1038/ng.3673  0.96
2015 Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, ... ... Attardi LD, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nature Medicine. PMID 26390243 DOI: 10.1038/nm.3952  0.96
2015 Younger ST, Kenzelmann-Broz D, Jung H, Attardi LD, Rinn JL. Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage. Nucleic Acids Research. 43: 4447-62. PMID 25883152 DOI: 10.1093/nar/gkv284  0.96
2015 Van Nostrand JL, Brisac A, Mello SS, Jacobs SB, Luong R, Attardi LD. The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development. Cancer Discovery. 5: 622-35. PMID 25813352 DOI: 10.1158/2159-8290.CD-14-0921  0.96
2015 Bieging KT, Attardi LD. A piece of the p53 puzzle Nature. 520: 37-38. PMID 25799989 DOI: 10.1038/nature14374  0.96
2015 Jiang D, LaGory EL, Kenzelmann Brož D, Bieging KT, Brady CA, Link N, Abrams JM, Giaccia AJ, Attardi LD. Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function. Cell Reports. 10: 1096-109. PMID 25704813 DOI: 10.1016/j.celrep.2015.01.043  0.96
2014 Van Nostrand JL, Attardi LD. Guilty as CHARGED: p53's expanding role in disease. Cell Cycle (Georgetown, Tex.). 13: 3798-807. PMID 25483057 DOI: 10.4161/15384101.2014.987627  0.36
2014 Van Nostrand JL, Brady CA, Jung H, Fuentes DR, Kozak MM, Johnson TM, Lin CY, Lin CJ, Swiderski DL, Vogel H, Bernstein JA, Attié-Bitach T, Chang CP, Wysocka J, Martin DM, ... Attardi LD, et al. Inappropriate p53 activation during development induces features of CHARGE syndrome. Nature. 514: 228-32. PMID 25119037 DOI: 10.1038/nature13585  0.36
2014 Li X, Nadauld L, Ootani A, Corney DC, Pai RK, Gevaert O, Cantrell MA, Rack PG, Neal JT, Chan CWM, Yeung T, Gong X, Yuan J, Wilhelmy J, Robine S, ... Attardi LD, et al. Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture Nature Medicine. 20: 769-777. PMID 24859528 DOI: 10.1038/nm.3585  0.96
2014 Bieging KT, Mello SS, Attardi LD. Unravelling mechanisms of p53-mediated tumour suppression Nature Reviews Cancer. 14: 359-370. PMID 24739573 DOI: 10.1038/nrc3711  0.96
2014 Garcia PB, Attardi LD. Illuminating p53 function in cancer with genetically engineered mouse models. Seminars in Cell & Developmental Biology. 27: 74-85. PMID 24394915 DOI: 10.1016/j.semcdb.2013.12.014  0.96
2014 Van Nostrand JL, Attardi LD. Guilty as CHARGED: P53's expanding role in disease Cell Cycle. 13: 3798-3806. DOI: 10.4161/15384101.2014.987627  0.96
2013 Broz DK, Attardi LD. TRP53 activates a global autophagy program to promote tumor suppression Autophagy. 9: 1440-1442. PMID 23899499 DOI: 10.4161/auto.25833  0.96
2013 Raj N, Attardi LD. Tumor suppression: P53 alters immune surveillance to restrain liver cancer Current Biology. 23: R527-R530. PMID 23787049 DOI: 10.1016/j.cub.2013.04.076  0.96
2013 Mello SS, Attardi LD. Not all p53 gain-of-function mutants are created equal Cell Death and Differentiation. 20: 855-857. PMID 23749181 DOI: 10.1038/cdd.2013.53  0.96
2013 Kenzelmann Broz D, Mello SS, Bieging KT, Jiang D, Dusek RL, Brady CA, Sidow A, Attardi LD. Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses Genes and Development. 27: 1016-1031. PMID 23651856 DOI: 10.1101/gad.212282.112  0.96
2013 Attardi LD, Sage J. RB goes mitochondrial Genes and Development. 27: 975-979. PMID 23651852 DOI: 10.1101/gad.219451.113  0.96
2013 Jiang D, Attardi LD. Engaging the p53 metabolic brake drives senescence Cell Research. 23: 739-740. PMID 23478296 DOI: 10.1038/cr.2013.34  0.96
2013 Kong CS, Cao H, Kwok S, Nguyen CM, Jordan RC, Beaudry VG, Attardi LD, Le QT. Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 115: 95-103. PMID 23217540 DOI: 10.1016/j.oooo.2012.10.017  0.96
2012 Baron S, Hoang A, Vogel H, Attardi LD. Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice. Plos One. 7: e50024. PMID 23185521 DOI: 10.1371/journal.pone.0050024  0.96
2012 Dusek RL, Bascom JL, Vogel H, Baron S, Borowsky AD, Bissell MJ, Attardi LD. Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer. Breast Cancer Research : Bcr. 14: R65. PMID 22515648 DOI: 10.1186/bcr3171  0.96
2012 Bieging KT, Attardi LD. Deconstructing p53 transcriptional networks in tumor suppression Trends in Cell Biology. 22: 97-106. PMID 22154076 DOI: 10.1016/j.tcb.2011.10.006  0.96
2012 Sage J, Attardi L, van Dyke T. Roles of p53 and pRB tumor suppressor networks in human cancer: Insight from studies in the engineered mouse Genetically Engineered Mice For Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing. 293-308. DOI: 10.1007/978-0-387-69805-2_14  0.96
2011 Jiang D, Brady CA, Johnson TM, Lee EY, Park EJ, Scott MP, Attardi LD. Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages. Proceedings of the National Academy of Sciences of the United States of America. 108: 17123-8. PMID 21969549 DOI: 10.1073/pnas.1111245108  0.96
2011 Brady CA, Jiang D, Mello SS, Johnson TM, Jarvis LA, Kozak MM, Kenzelmann Broz D, Basak S, Park EJ, McLaughlin ME, Karnezis AN, Attardi LD. Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression. Cell. 145: 571-83. PMID 21565614 DOI: 10.1016/j.cell.2011.03.035  0.96
2011 Dusek RL, Attardi LD. Desmosomes: New perpetrators in tumour suppression Nature Reviews Cancer. 11: 317-323. PMID 21508970 DOI: 10.1038/nrc3051  0.96
2011 Renault VM, Thekkat PU, Hoang KL, White JL, Brady CA, Kenzelmann Broz D, Venturelli OS, Johnson TM, Oskoui PR, Xuan Z, Santo EE, Zhang MQ, Vogel H, Attardi LD, Brunet A. The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. Oncogene. 30: 3207-21. PMID 21423206 DOI: 10.1038/onc.2011.35  0.96
2011 Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD. PERP regulates enamel formation via effects on cell-cell adhesion and gene expression Journal of Cell Science. 124: 745-754. PMID 21285247 DOI: 10.1242/jcs.078071  0.96
2010 Beaudry VG, Jiang D, Dusek RL, Park EJ, Knezevich S, Ridd K, Vogel H, Bastian BC, Attardi LD. Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis. Plos Genetics. 6: e1001168. PMID 20975948 DOI: 10.1371/journal.pgen.1001168  0.96
2010 Brady CA, Attardi LD. p53 at a glance Journal of Cell Science. 123: 2527-2532. PMID 20940128 DOI: 10.1242/jcs.064501  0.96
2010 Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, Khalil AM, Zuk O, Amit I, Rabani M, Attardi LD, Regev A, Lander ES, Jacks T, Rinn JL. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 142: 409-19. PMID 20673990 DOI: 10.1016/j.cell.2010.06.040  0.96
2010 Beaudry VG, Ihrie RA, Jacobs SB, Nguyen B, Pathak N, Park E, Attardi LD. Loss of the desmosomal component perp impairs wound healing in vivo. Dermatology Research and Practice. 2010: 759731. PMID 20628490 DOI: 10.1155/2010/759731  0.96
2010 Brož DK, Attardi LD. In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models Carcinogenesis. 31: 1311-1318. PMID 20097732 DOI: 10.1093/carcin/bgp331  0.96
2009 Beaudry VG, Attardi LD. SKP-ing TAp63: Stem Cell Depletion, Senescence, and Premature Aging Cell Stem Cell. 5: 1-2. PMID 19570504 DOI: 10.1016/j.stem.2009.06.015  0.96
2009 Fete M, vanBokhoven H, Clements SE, McKeon F, Roop DR, Koster MI, Missero C, Attardi LD, Lombillo VA, Ratovitski E, Julapalli M, Ruths D, Sybert VP, Siegfried EC, Bree AF. International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome. American Journal of Medical Genetics. Part A. 149: 1885-93. PMID 19353643 DOI: 10.1002/ajmg.a.32761  0.96
2009 Beaudry VG, Pathak N, Koster MI, Attardi LD. Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis American Journal of Medical Genetics, Part A. 149: 1952-1957. PMID 19353588 DOI: 10.1002/ajmg.a.32760  0.96
2009 Nguyen B, Dusek RL, Beaudry VG, Marinkovich MP, Attardi LD. Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies Journal of Investigative Dermatology. 129: 1710-1718. PMID 19158843 DOI: 10.1038/jid.2008.419  0.96
2008 McGowan KA, Li JZ, Park CY, Beaudry V, Tabor HK, Sabnis AJ, Zhang W, Fuchs H, de Angelis MH, Myers RM, Attardi LD, Barsh GS. Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects. Nature Genetics. 40: 963-70. PMID 18641651 DOI: 10.1038/ng.188  0.96
2008 Basak S, Jacobs SB, Krieg AJ, Pathak N, Zeng Q, Kaldis P, Giaccia AJ, Attardi LD. The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation. Molecular Cell. 30: 303-14. PMID 18471976 DOI: 10.1016/j.molcel.2008.04.002  0.96
2008 Johnson TM, Meade K, Pathak N, Marques MR, Attardi LD. Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence Proceedings of the National Academy of Sciences of the United States of America. 105: 1215-1220. PMID 18216268 DOI: 10.1073/pnas.0706764105  0.96
2007 Barsh G, Attardi LD. A healthy tan? New England Journal of Medicine. 356: 2208-2210. PMID 17522405 DOI: 10.1056/NEJMcibr071775  0.96
2007 Wijnhoven SWP, Speksnijder EN, Liu X, Zwart E, VanOostrom CTM, Beems RB, Hoogervorst EM, Schaap MM, Attardi LD, Jacks T, Van Steeg H, Jonkers J, De Vries A. Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage Cancer Research. 67: 4648-4656. PMID 17510390 DOI: 10.1158/0008-5472.CAN-06-4681  0.96
2007 Jacobs SB, Basak S, Murray JI, Pathak N, Attardi LD. Siva is an apoptosis-selective p53 target gene important for neuronal cell death. Cell Death and Differentiation. 14: 1374-85. PMID 17464332 DOI: 10.1038/sj.cdd.4402128  0.96
2007 Carroll DK, Brugge JS, Attardi LD. p63, cell adhesion and survival Cell Cycle. 6: 255-261. PMID 17297292  0.96
2006 Hammond EM, Mandell DJ, Salim A, Krieg AJ, Johnson TM, Shirazi HA, Attardi LD, Giaccia AJ. Genome-wide analysis of p53 under hypoxic conditions Molecular and Cellular Biology. 26: 3492-3504. PMID 16611991 DOI: 10.1128/MCB.26.9.3492-3504.2006  0.96
2006 Johnson TM, Attardi LD. Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice Cell Death and Differentiation. 13: 902-908. PMID 16557272 DOI: 10.1038/sj.cdd.4401902  0.96
2006 Ihrie RA, Bronson RT, Attardi LD. Adult mice lacking the p53/p63 target gene Perp are not predisposed to spontaneous tumorigenesis but display features of ectodermal dysplasia syndromes [2] Cell Death and Differentiation. 13: 1614-1618. PMID 16485031 DOI: 10.1038/sj.cdd.4401871  0.96
2006 Marques MR, Ihrie RA, Horner JS, Attardi LD. The requirement for Perp in postnatal viability and epithelial integrity reflects an intrinsic role in stratified epithelia Journal of Investigative Dermatology. 126: 69-73. PMID 16417219 DOI: 10.1038/sj.jid.5700032  0.96
2006 Johnson TM, Attardi LD. In reply [2] Nature Genetics. 38: 396-397. DOI: 10.1038/ng0406-396  0.96
2005 Marques MR, Horner JS, Ihrie RA, Bronson RT, Attardi LD. Mice lacking the p53/p63 target gene Perp are resistant to papilloma development Cancer Research. 65: 6551-6556. PMID 16061634 DOI: 10.1158/0008-5472.CAN-05-0366  0.96
2005 Attardi LD, Donehower LA. Probing p53 biological functions through the use of genetically engineered mouse models Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 576: 4-21. PMID 16038709 DOI: 10.1016/j.mrfmmm.2004.08.022  0.96
2005 Ihrie RA, Attardi LD. A new perp in the lineup: Linking p63 and desmosomal adhesion Cell Cycle. 4: 873-876. PMID 15970683  0.96
2005 Johnson TM, Attardi LD. p53QS: An old mutant teaches us new tricks Cell Cycle. 4: 731-734. PMID 15908788  0.96
2005 Artandi SE, Attardi LD. Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer. Biochemical and Biophysical Research Communications. 331: 881-90. PMID 15865944 DOI: 10.1016/j.bbrc.2005.03.211  0.96
2005 Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD. Perp is a p63-regulated gene essential for epithelial integrity Cell. 120: 843-856. PMID 15797384 DOI: 10.1016/j.cell.2005.01.008  0.96
2005 Brown MM, Attardi LD. The role of apoptosis in cancer development and treatment response Nature Reviews Cancer. 5: 231-237. PMID 15738985 DOI: 10.1038/nrc1570  0.96
2005 Johnson TM, Hammond EM, Giaccia A, Attardi LD. The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality Nature Genetics. 37: 145-152. PMID 15654339 DOI: 10.1038/ng1498  0.96
2005 Attardi LD. The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: Lessons from mouse models Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 569: 145-157. PMID 15603759 DOI: 10.1016/j.mrfmmm.2004.04.019  0.96
2004 Bruins W, Zwart E, Attardi LD, Iwakuma T, Hoogervorst EM, Beems RB, Miranda B, Van Oostrom CTM, Van Den Berg J, Van Den Aardweg GJ, Lozano G, Van Steeg H, Jacks T, De Vries A. Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389 Molecular and Cellular Biology. 24: 8884-8894. PMID 15456863 DOI: 10.1128/MCB.24.20.8884-8894.2004  0.96
2004 Beer S, Zetterberg A, Ihrie RA, McTaggart RA, Yang Q, Bradon N, Arvanitis C, Attardi LD, Feng S, Ruebner B, Cardiff RD, Felsher DW. Developmental context determines latency of MYC-induced tumorigenesis Plos Biology. 2. PMID 15455033 DOI: 10.1371/journal.pbio.0020332  0.96
2004 Attardi LD, De Vries A, Jacks T. Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer Oncogene. 23: 973-980. PMID 14749764 DOI: 10.1038/sj.onc.1207026  0.96
2004 Ihrie RA, Attardi LD. Perp-etrating p53-dependent apoptosis Cell Cycle. 3: 267-269. PMID 14726658  0.96
2004 Attardi LD, DePinho RA. Conquering the complexity of p53. Nature Genetics. 36: 7-8. PMID 14702030 DOI: 10.1038/ng0104-7  0.96
2003 Reczek EE, Flores ER, Tsay AS, Attardi LD, Jacks T. Multiple Response Elements and Differential p53 Binding Control Perp Expression during Apoptosis Molecular Cancer Research. 1: 1048-1057. PMID 14707288  0.96
2003 Ihrie RA, Reczek E, Horner JS, Khachatrian L, Sage J, Jacks T, Attardi LD. Perp Is a Mediator of p53-Dependent Apoptosis in Diverse Cell Types Current Biology. 13: 1985-1990. PMID 14614825 DOI: 10.1016/j.cub.2003.10.055  0.96
2000 Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, Jacks T. Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization Genes and Development. 14: 3037-3050. PMID 11114892 DOI: 10.1101/gad.843200  0.96
2000 Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW, Jacks T. PERP, an apoptosis-associated target of p53, in a novel member of the PMP-22/gas3 family Genes and Development. 14: 704-718. PMID 10733530  0.96
1999 Attardi LD, Jacks T. The role of p53 in tumour suppression: Lessons from mouse models Cellular and Molecular Life Sciences. 55: 48-63. PMID 10065151 DOI: 10.1007/s000180050269  0.96
1997 Jones JM, Attardi L, Godley LA, Laucirica R, Medina D, Jacks T, Varmus HE, Donehower LA. Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 8: 829-38. PMID 9269892  0.96
1996 Attardi LD, Lowe SW, Brugarolas J, Jacks T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis Embo Journal. 15: 3693-3701. PMID 8758936  0.96
1995 Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T. A subset of p53-deficient embryos exhibit exencephaly Nature Genetics. 10: 175-180. PMID 7663512 DOI: 10.1038/ng0695-175  0.96
1994 Chen JL, Attardi LD, Verrijzer CP, Yokomori K, Tjian R. Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators Cell. 79: 93-105. PMID 7923382 DOI: 10.1016/0092-8674(94)90403-0  0.96
1993 Attardi LD, Tjian R. Drosophila tissue-specific transcription factor NTF-1 contains a novel isoleucinerich activation motif Genes and Development. 7: 1341-1353. PMID 8330738  0.96
1993 Attardi LD, Von Seggern D, Tjian R. Ectopic expression of wild-type or a dominant-negative mutant of transcription factor NTF-1 disrupts normal Drosophila development. Proceedings of the National Academy of Sciences of the United States of America. 90: 10563-7. PMID 8248145  0.96
1990 Yu GL, Bradley JD, Attardi LD, Blackburn EH. In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs Nature. 344: 126-132. PMID 1689810  0.96
1989 Dynlacht BD, Attardi LD, Admon A, Freeman M, Tjian R. Functional analysis of NTF-1, a developmentally regulated Drosophila transcription factor that binds neuronal cis elements. Genes & Development. 3: 1677-88. PMID 2606344  0.96
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