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Alexander G. Kozlov - Publications

Affiliations: 
Biochemistry and Molecular Biophysics Washington University School of Medicine, St. Louis, MO, United States 
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58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bonde NJ, Kozlov AG, Cox MM, Lohman TM, Keck JL. Molecular insights into the prototypical single-stranded DNA-binding protein from . Critical Reviews in Biochemistry and Molecular Biology. 1-29. PMID 38770626 DOI: 10.1080/10409238.2024.2330372  0.602
2023 Chadda A, Kozlov AG, Nguyen B, Lohman TM, Galburt EA. Mycobacterium tuberculosis Ku stimulates multi-round DNA unwinding by UvrD1 monomers. Journal of Molecular Biology. 168367. PMID 37972687 DOI: 10.1016/j.jmb.2023.168367  0.73
2023 Shinn MK, Chaturvedi SK, Kozlov AG, Lohman TM. Allosteric effects of E. coli SSB and RecR proteins on RecO protein binding to DNA. Nucleic Acids Research. PMID 36808259 DOI: 10.1093/nar/gkad084  0.862
2022 Kozlov AG, Cheng X, Zhang H, Shinn MK, Weiland E, Nguyen B, Shkel IA, Zytkiewicz E, Finkelstein IJ, Record MT, Lohman TM. How Glutamate Promotes Liquid-liquid Phase Separation and DNA Binding Cooperativity of E. coli SSB Protein. Journal of Molecular Biology. 434: 167562. PMID 35351518 DOI: 10.1016/j.jmb.2022.167562  0.826
2021 Kozlov AG, Lohman TM. Probing E. coli SSB Protein-DNA topology by reversing DNA backbone polarity. Biophysical Journal. PMID 33636169 DOI: 10.1016/j.bpj.2021.02.025  0.746
2021 Shinn MK, Kozlov AG, Lohman TM. Allosteric effects of SSB C-terminal tail on assembly of E. coli RecOR proteins. Nucleic Acids Research. PMID 33450019 DOI: 10.1093/nar/gkaa1291  0.84
2020 Dubiel K, Henry C, Spenkelink LM, Kozlov AG, Wood EA, Jergic S, Dixon NE, van Oijen AM, Cox MM, Lohman TM, Sandler SJ, Keck JL. Development of a single-stranded DNA-binding protein fluorescent fusion toolbox. Nucleic Acids Research. PMID 32374866 DOI: 10.1093/Nar/Gkaa320  0.747
2020 McConnell P, Mekel M, Kozlov AG, Mooren OL, Lohman TM, Cooper JA. Comparative analysis of CPI-motif regulation of biochemical functions of actin capping protein. Biochemistry. PMID 32133840 DOI: 10.1021/Acs.Biochem.0C00092  0.583
2020 McConnell P, Mekel M, Kozlov AG, Mooren OL, Lohman TM, Cooper JA. CPI-motif Regulation of Biochemical Functions of Actin Capping Protein Biophysical Journal. 118: 123a. DOI: 10.1016/J.Bpj.2019.11.807  0.532
2020 Kozlov AG, Kyung Shinn M, Lohman TM. Regulation of Nearest-Neighbor Cooperative Binding of E. coli SSB Protein to Ssdna by its Intrinsically Disordered Regions Biophysical Journal. 118: 70a. DOI: 10.1016/j.bpj.2019.11.560  0.655
2020 Shinn MK, Kozlov AG, Lohman TM. Assembly and Binding of E. coli RecOR Proteins to SSB C-Terminal Tails Biophysical Journal. 118: 374a. DOI: 10.1016/j.bpj.2019.11.2137  0.667
2019 Kozlov AG, Shinn MK, Lohman TM. Regulation of Nearest-Neighbor Cooperative Binding of E. coli SSB Protein to DNA. Biophysical Journal. PMID 31708161 DOI: 10.1016/j.bpj.2019.09.047  0.853
2019 Ordabayev YA, Nguyen B, Kozlov AG, Jia H, Lohman TM. UvrD helicase activation by MutL involves rotation of its 2B subdomain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31363055 DOI: 10.1073/pnas.1905513116  0.775
2019 Shinn MK, Kozlov AG, Nguyen B, Bujalowski WM, Lohman TM. Are the intrinsically disordered linkers involved in SSB binding to accessory proteins? Nucleic Acids Research. PMID 31329947 DOI: 10.1093/nar/gkz606  0.849
2019 Nguyen B, Ciuba MA, Kozlov AG, Levitus M, Lohman TM. Protein Environment and DNA Orientation Affect Protein-Induced Cy3 Fluorescence Enhancement. Biophysical Journal. PMID 31235181 DOI: 10.1016/J.Bpj.2019.05.026  0.724
2019 Kyung Shinn M, Kozlov AG, Lohman TM. Binding Specificity of E. coli SSB C-Terminal Tails to SIPs Biophysical Journal. 116: 77a. DOI: 10.1016/j.bpj.2018.11.460  0.644
2018 Dubiel K, Myers AR, Kozlov AG, Yang O, Zhang J, Ha T, Lohman TM, Keck JL. Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins. Journal of Molecular Biology. PMID 30472092 DOI: 10.1016/J.Jmb.2018.11.019  0.772
2018 Johnson B, McConnell P, Kozlov AG, Mekel M, Lohman TM, Gross ML, Amarasinghe GK, Cooper JA. Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange. Cell Reports. 23: 2795-2804. PMID 29847807 DOI: 10.1016/J.Celrep.2018.04.096  0.646
2018 Kyung Shinn M, Kozlov AG, Lohman TM. Allosteric Effect of E. coli SSB C-Terminal Tails on RecOR Binding to DNA Biophysical Journal. 114: 441a. DOI: 10.1016/J.BPJ.2017.11.2439  0.712
2017 Kozlov AG, Shinn MK, Weiland EA, Lohman TM. Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions. Journal of Molecular Biology. PMID 28782560 DOI: 10.1016/j.jmb.2017.07.021  0.867
2017 Kozlov AG, Kyung Shinn M, Lohman TM. The Role of Intrinsically Disordered Linker and Salt Type on Cooperativity of E. Coli SSB Binding to ssDNA Biophysical Journal. 112: 208a. DOI: 10.1016/j.bpj.2016.11.1150  0.625
2016 Sokoloski JE, Kozlov AG, Galletto R, Lohman TM. Chemo-mechanical pushing of proteins along single-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 27185951 DOI: 10.1073/Pnas.1602878113  0.834
2016 Waldman VM, Weiland E, Kozlov AG, Lohman TM. Is a fully wrapped SSB-DNA complex essential for Escherichia coli survival? Nucleic Acids Research. PMID 27084941 DOI: 10.1093/nar/gkw262  0.85
2016 Sokoloski JE, Kozlov A, Galletto R, Lohman TM. Single Stranded DNA Translocases can Push Single Stranded DNA Binding Proteins along Single Stranded DNA Biophysical Journal. 110: 240a. DOI: 10.1016/J.Bpj.2015.11.1321  0.831
2015 Suksombat S, Khafizov R, Kozlov AG, Lohman TM, Chemla YR. Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways. Elife. 4. PMID 26305498 DOI: 10.7554/Elife.08193  0.771
2015 Kozlov AG, Weiland E, Mittal A, Waldman V, Antony E, Fazio N, Pappu RV, Lohman TM. Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA. Journal of Molecular Biology. 427: 763-74. PMID 25562210 DOI: 10.1016/J.Jmb.2014.12.020  0.802
2015 Suksombat S, Khafizov R, Kozlov AG, Lohman TM, Chemla YR. Author response: Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways Elife. DOI: 10.7554/Elife.08193.024  0.525
2014 Lee KS, Marciel AB, Kozlov AG, Schroeder CM, Lohman TM, Ha T. Ultrafast redistribution of E. coli SSB along long single-stranded DNA via intersegment transfer. Journal of Molecular Biology. 426: 2413-21. PMID 24792418 DOI: 10.1016/J.Jmb.2014.04.023  0.671
2014 Suksombat S, Kozlov AG, Lohman TM, Chemla YR. Partial Unwrapping of SSB from SsDNA Facilitates RecA Filament Formation Biophysical Journal. 106: 698a-699a. DOI: 10.1016/J.Bpj.2013.11.3864  0.727
2013 Antony E, Weiland E, Yuan Q, Manhart CM, Nguyen B, Kozlov AG, McHenry CS, Lohman TM. Multiple C-terminal tails within a single E. coli SSB homotetramer coordinate DNA replication and repair. Journal of Molecular Biology. 425: 4802-19. PMID 24021816 DOI: 10.1016/J.Jmb.2013.08.021  0.836
2012 Kozlov AG, Galletto R, Lohman TM. SSB-DNA binding monitored by fluorescence intensity and anisotropy. Methods in Molecular Biology (Clifton, N.J.). 922: 55-83. PMID 22976177 DOI: 10.1007/978-1-62703-032-8_4  0.731
2012 Kozlov AG, Lohman TM. SSB binding to ssDNA using isothermal titration calorimetry. Methods in Molecular Biology (Clifton, N.J.). 922: 37-54. PMID 22976176 DOI: 10.1007/978-1-62703-032-8_3  0.754
2012 Antony E, Kozlov AG, Nguyen B, Lohman TM. Plasmodium falciparum SSB tetramer binds single-stranded DNA only in a fully wrapped mode. Journal of Molecular Biology. 420: 284-95. PMID 22543238 DOI: 10.1016/J.Jmb.2012.04.022  0.873
2012 Ha T, Kozlov AG, Lohman TM. Single-molecule views of protein movement on single-stranded DNA. Annual Review of Biophysics. 41: 295-319. PMID 22404684 DOI: 10.1146/Annurev-Biophys-042910-155351  0.652
2011 Zhou R, Kozlov AG, Roy R, Zhang J, Korolev S, Lohman TM, Ha T. SSB functions as a sliding platform that migrates on DNA via reptation. Cell. 146: 222-32. PMID 21784244 DOI: 10.1016/J.Cell.2011.06.036  0.708
2011 Kozlov AG, Lohman TM. E. coli SSB tetramer binds the first and second molecules of (dT)(35) with heat capacities of opposite sign. Biophysical Chemistry. 159: 48-57. PMID 21636209 DOI: 10.1016/j.bpc.2011.05.005  0.67
2010 Kozlov AG, Eggington JM, Cox MM, Lohman TM. Binding of the dimeric Deinococcus radiodurans single-stranded DNA binding protein to single-stranded DNA. Biochemistry. 49: 8266-75. PMID 20795631 DOI: 10.1021/Bi100920W  0.768
2010 Kozlov AG, Cox MM, Lohman TM. Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein. The Journal of Biological Chemistry. 285: 17246-52. PMID 20360609 DOI: 10.1074/Jbc.M110.118273  0.788
2010 Kozlov AG, Jezewska MJ, Bujalowski W, Lohman TM. Binding specificity of Escherichia coli single-stranded DNA binding protein for the chi subunit of DNA pol III holoenzyme and PriA helicase. Biochemistry. 49: 3555-66. PMID 20329707 DOI: 10.1021/Bi100069S  0.849
2010 Kozlov AG, Bujalowski W, Lohman TM. Specificity of E.coli SSB Protein Binding To the Chi Subunit of DNA Pol III He and Pria Helicase in the Presence and Absence of ssDNA Biophysical Journal. 98: 65a. DOI: 10.1016/J.Bpj.2009.12.370  0.772
2010 Khafizov RG, Kozlov AG, Lohman TM, Chemla Y. E.coli SSB Under Tension Biophysical Journal. 98: 270a. DOI: 10.1016/J.Bpj.2009.12.1470  0.783
2010 Zhou R, Roy R, Kozlov AG, Lohman TM, Ha T. Probing Protein Diffusion and Dissociation Mechanisms on DNA Using Fluorescence-Force Spectroscopy Biophysical Journal. 98: 269a. DOI: 10.1016/J.Bpj.2009.12.1464  0.67
2009 Roy R, Kozlov AG, Lohman TM, Ha T. SSB protein diffusion on single-stranded DNA stimulates RecA filament formation. Nature. 461: 1092-7. PMID 19820696 DOI: 10.1038/Nature08442  0.727
2009 Roy R, Kozlov AG, Lohman TM, Ha T. Erratum: SSB protein diffusion on single-stranded DNA stimulates RecA filament formation Nature. 462: 944-944. DOI: 10.1038/Nature08600  0.611
2008 Shereda RD, Kozlov AG, Lohman TM, Cox MM, Keck JL. SSB as an organizer/mobilizer of genome maintenance complexes. Critical Reviews in Biochemistry and Molecular Biology. 43: 289-318. PMID 18937104 DOI: 10.1080/10409230802341296  0.677
2007 Roy R, Kozlov AG, Lohman TM, Ha T. Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein. Journal of Molecular Biology. 369: 1244-57. PMID 17490681 DOI: 10.1016/J.Jmb.2007.03.079  0.784
2006 Eggington JM, Kozlov AG, Cox MM, Lohman TM. Polar destabilization of DNA duplexes with single-stranded overhangs by the Deinococcus radiodurans SSB protein. Biochemistry. 45: 14490-502. PMID 17128988 DOI: 10.1021/Bi061178M  0.71
2006 Kumaran S, Kozlov AG, Lohman TM. Saccharomyces cerevisiae replication protein A binds to single-stranded DNA in multiple salt-dependent modes. Biochemistry. 45: 11958-73. PMID 17002295 DOI: 10.1021/bi060994r  0.783
2006 Kuznetsov SV, Kozlov AG, Lohman TM, Ansari A. Microsecond dynamics of protein-DNA interactions: direct observation of the wrapping/unwrapping kinetics of single-stranded DNA around the E. coli SSB tetramer. Journal of Molecular Biology. 359: 55-65. PMID 16677671 DOI: 10.1016/J.Jmb.2006.02.070  0.785
2006 Kozlov AG, Lohman TM. Effects of monovalent anions on a temperature-dependent heat capacity change for Escherichia coli SSB tetramer binding to single-stranded DNA. Biochemistry. 45: 5190-205. PMID 16618108 DOI: 10.1021/bi052543x  0.68
2004 Savvides SN, Raghunathan S, Fütterer K, Kozlov AG, Lohman TM, Waksman G. The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA. Protein Science : a Publication of the Protein Society. 13: 1942-7. PMID 15169953 DOI: 10.1110/Ps.04661904  0.679
2002 Kozlov AG, Lohman TM. Kinetic mechanism of direct transfer of Escherichia coli SSB tetramers between single-stranded DNA molecules. Biochemistry. 41: 11611-27. PMID 12269804 DOI: 10.1021/bi020361m  0.615
2002 Kozlov AG, Lohman TM. Stopped-flow studies of the kinetics of single-stranded DNA binding and wrapping around the Escherichia coli SSB tetramer. Biochemistry. 41: 6032-44. PMID 11993998 DOI: 10.1021/bi020122z  0.681
2000 Kozlov AG, Lohman TM. Large contributions of coupled protonation equilibria to the observed enthalpy and heat capacity changes for ssDNA binding to Escherichia coli SSB protein. Proteins. 8-22. PMID 11013397 DOI: 10.1002/1097-0134(2000)41:4+<8::AID-PROT20>3.0.CO;2-H  0.606
2000 Raghunathan S, Kozlov AG, Lohman TM, Waksman G. Structure of the DNA binding domain of E. coli SSB bound to ssDNA. Nature Structural Biology. 7: 648-52. PMID 10932248 DOI: 10.1038/77943  0.749
1999 Kozlov AG, Lohman TM. Adenine base unstacking dominates the observed enthalpy and heat capacity changes for the Escherichia coli SSB tetramer binding to single-stranded oligoadenylates. Biochemistry. 38: 7388-97. PMID 10353851 DOI: 10.1021/bi990309z  0.661
1998 Kozlov AG, Lohman TM. Calorimetric studies of E. coli SSB protein-single-stranded DNA interactions. Effects of monovalent salts on binding enthalpy. Journal of Molecular Biology. 278: 999-1014. PMID 9600857 DOI: 10.1006/jmbi.1998.1738  0.68
1996 Lohman TM, Overman LB, Ferrari ME, Kozlov AG. A highly salt-dependent enthalpy change for Escherichia coli SSB protein-nucleic acid binding due to ion-protein interactions. Biochemistry. 35: 5272-9. PMID 8611514 DOI: 10.1021/Bi9527606  0.828
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