Jennifer M. Beierlein, Ph.D.
Affiliations: | 2011 | University of Connecticut, Storrs, CT, United States |
Area:
X-Ray crystallography, Structural biology, Molecular modeling, Structure-based drug designGoogle:
"Jennifer Beierlein"Mean distance: 9.95 | S | N | B | C | P |
Parents
Sign in to add mentor| Amy Christine Anderson | grad student | 2011 | University of Connecticut | |
| (Structural and Synthetic Studies into Novel Antifolates Targeting Bacillus anthracis Dihydrofolate Reductase.) | ||||
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Publications
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| Beierlein JM, Anderson AC. (2011) New developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis. Current Medicinal Chemistry. 18: 5083-94 |
| Beierlein JM, Karri NG, Anderson AC. (2010) Targeted mutations of Bacillus anthracis dihydrofolate reductase condense complex structure−activity relationships. Journal of Medicinal Chemistry. 53: 7327-36 |
| Beierlein JM, Deshmukh L, Frey KM, et al. (2009) The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors. Biochemistry. 48: 4100-8 |
| deshmukh l, vinogradova o, beierlein j, et al. (2009) Solution structure of Bacillus anthracis dihydrofolate reductase Journal of Back and Musculoskeletal Rehabilitation |
| Beierlein JM, Frey KM, Bolstad DB, et al. (2008) Synthetic and crystallographic studies of a new inhibitor series targeting Bacillus anthracis dihydrofolate reductase. Journal of Medicinal Chemistry. 51: 7532-40 |
| Pelphrey PM, Popov VM, Joska TM, et al. (2007) Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis. Journal of Medicinal Chemistry. 50: 940-50 |