David K. Breslow, Ph.D.

Affiliations: 
2010 Chemistry and Chemical Biology University of California, San Francisco, San Francisco, CA 
Area:
Proteomics, Protein Folding, and Prion-Based Inheritance in Disease and Normal Biology
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"David Breslow"
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Parents

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Jonathan S. Weissman grad student 2010 UCSF
 (Development of a high-resolution growth assay for yeast functional genomics and identification of Orm family proteins as key mediators of Sphingolipid homeostasis.)
Maxence V Nachury post-doc 2011-2016 Stanford Medical School (Cell Biology Tree)
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Publications

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Ganga AK, Sweeney LK, Rubio Ramos A, et al. (2024) A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function. Biorxiv : the Preprint Server For Biology
Bruel AL, Ganga AK, Nosková L, et al. (2023) Pathogenic RAB34 variants impair primary cilium assembly and cause a novel oral-facial-digital syndrome. Human Molecular Genetics
Ganga AK, Kennedy MC, Oguchi ME, et al. (2021) Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway. Current Biology : Cb
Breslow DK, Holland AJ. (2019) Mechanism and Regulation of Centriole and Cilium Biogenesis. Annual Review of Biochemistry
Breslow DK, Hoogendoorn S, Kopp AR, et al. (2018) A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Nature Genetics
Breslow DK, Nachury MV. (2015) Analysis of soluble protein entry into primary cilia using semipermeabilized cells. Methods in Cell Biology. 127: 203-21
Liew GM, Ye F, Nager AR, et al. (2014) The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3. Developmental Cell. 31: 265-78
Breslow DK, Koslover EF, Seydel F, et al. (2013) An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. The Journal of Cell Biology. 203: 129-47
Ye F, Breslow DK, Koslover EF, et al. (2013) Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors. Elife. 2: e00654
Breslow DK. (2013) Sphingolipid homeostasis in the endoplasmic reticulum and beyond. Cold Spring Harbor Perspectives in Biology. 5: a013326
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