Daniel Knutson

Affiliations: 
2020 Department of Chemistry and Biochemistry University of Wisconsin-Milwaukee, Milwaukee, WI 
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Mitrović JR, Bjelošević Žiberna M, Vukadinović A, et al. (2023) Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 189: 106557
Huang YH, Lee MT, Hsueh HY, et al. (2023) Cerebellar α6GABA Receptors as a Therapeutic Target for Essential Tremor: Proof-of-Concept Study with Ethanol and Pyrazoloquinolinones. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Mitrović JR, Divović-Matović B, Knutson DE, et al. (2023) High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. International Journal of Pharmaceutics. 633: 122613
Lee MT, Mouri A, Kubota H, et al. (2022) Targeting α6GABA receptors as a novel therapy for schizophrenia: A proof-of-concept preclinical study using various animal models. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 150: 113022
Witkin JM, Lippa A, Smith JL, et al. (2022) The imidazodiazepine, KRM-II-81: An example of a newly emerging generation of GABAkines for neurological and psychiatric disorders. Pharmacology, Biochemistry, and Behavior. 213: 173321
Roni MSR, Zahn NM, Mikulsky BN, et al. (2021) Identification and Quantification of MIDD0301 metabolites. Current Drug Metabolism
Santrač A, Batinić B, Stamenić TT, et al. (2021) Positive modulation of α5GABAA receptors leads to dichotomous effects in rats on memory pattern and GABRA5 expression in prefrontal cortex and hippocampus. Behavioural Brain Research. 113578
Duke AN, Tiruveedhula VVNPB, Sharmin D, et al. (2021) Tolerance and dependence following chronic alprazolam treatment in rhesus monkeys: Role of GABA receptor subtypes. Drug and Alcohol Dependence. 228: 108985
Mitrović JR, Divović-Matović B, Knutson DE, et al. (2021) Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach. Pharmaceutics. 13
Cadeddu R, Knutson DE, Mosher LJ, et al. (2021) The α6 GABA Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome. Biomolecules. 11
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