☰

Daniel J. Brat, MD, Mayo Clinic 1994 PhD, Mayo Clinic 1994 - Publications

Affiliations: 
Pathology Emory University, Atlanta, GA 
Area:
Cancer Biology Neuropathology
Website:
http://pathology.emory.edu/AdminFacultyMember.cfm?Name_seq=545
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Year Citation  Score
2023 Rashidi A, Billingham LK, Zolp A, Chia TY, Silvers C, Katz JL, Park CH, Delay S, Boland L, Geng Y, Markwell SM, Dmello C, Arrieta VA, Zilinger K, Jacob IM, ... ... Brat DJ, et al. Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth. Cell Metabolism. PMID 38134929 DOI: 10.1016/j.cmet.2023.11.013  0.301
2022 Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, et al. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. PMID 35649412 DOI: 10.1016/j.cell.2022.04.038  0.309
2022 Dhar S, Gadd S, Patel P, Vaynshteyn J, Raju GP, Hashizume R, Brat DJ, Becher OJ. A tumor suppressor role for EZH2 in diffuse midline glioma pathogenesis. Acta Neuropathologica Communications. 10: 47. PMID 35395831 DOI: 10.1186/s40478-022-01336-5  0.32
2022 Pratt D, Abdullaev Z, Papanicolau-Sengos A, Ketchum C, Panneer Selvam P, Chung HJ, Lee I, Raffeld M, Gilbert MR, Armstrong TS, Pytel P, Borys E, Klonoski JM, McCord M, Horbinski C, ... Brat D, et al. High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13. Acta Neuropathologica. PMID 35103816 DOI: 10.1007/s00401-022-02404-9  0.31
2022 Markwell SM, Ross JL, Olson CL, Brat DJ. Necrotic reshaping of the glioma microenvironment drives disease progression. Acta Neuropathologica. PMID 35039931 DOI: 10.1007/s00401-021-02401-4  0.311
2020 Ostrom QT, Truitt G, Gittleman H, Brat DJ, Kruchko C, Wilson R, Barnholtz-Sloan JS. Relative survival after diagnosis with a primary brain or other central nervous system tumor in the National Program of Cancer Registries, 2004 to 2014. Neuro-Oncology Practice. 7: 306-312. PMID 32537180 DOI: 10.1093/Nop/Npz059  0.336
2020 Kam KL, Appin CL, Mao Q, Ikegami S, Lukas RV, Nikiforova MN, Roy S, Brat DJ, Horbinski C. Is Next-Generation Sequencing Alone Sufficient to Reliably Diagnose Gliomas? Journal of Neuropathology and Experimental Neurology. PMID 32483596 DOI: 10.1093/Jnen/Nlaa044  0.405
2020 Feldman AZ, Jennings LJ, Wadhwani NR, Brat DJ, Horbinski CM. The Essentials of Molecular Testing in CNS Tumors: What to Order and How to Integrate Results. Current Neurology and Neuroscience Reports. 20: 23. PMID 32445025 DOI: 10.1007/S11910-020-01041-7  0.354
2020 Louis DN, Wesseling P, Aldape K, Brat DJ, Capper D, Cree IA, Eberhart C, Figarella-Branger D, Fouladi M, Fuller GN, Giannini C, Haberler C, Hawkins C, Komori T, Kros JM, et al. cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading. Brain Pathology (Zurich, Switzerland). PMID 32307792 DOI: 10.1111/Bpa.12832  0.39
2020 Dundar B, Markwell SM, Sharma NV, Olson CL, Mukherjee S, Brat DJ. Methods for in vitro modeling of glioma invasion: Choosing tools to meet the need. Glia. PMID 32134155 DOI: 10.1002/Glia.23813  0.36
2019 Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, ... ... Brat DJ, et al. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. PMID 31748746 DOI: 10.1038/S41586-019-1775-1  0.359
2019 Kaffes I, Szulzewsky F, Chen Z, Herting CJ, Gabanic B, Velázquez Vega JE, Shelton J, Switchenko JM, Ross JL, McSwain LF, Huse JT, Westermark B, Nelander S, Forsberg-Nilsson K, Uhrbom L, ... ... Brat DJ, et al. Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors. Oncoimmunology. 8: e1655360. PMID 31646100 DOI: 10.1080/2162402X.2019.1655360  0.414
2019 Logun MT, Wynens KE, Simchick G, Zhao W, Mao L, Zhao Q, Mukherjee S, Brat DJ, Karumbaiah L. Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802610RR. PMID 31398290 DOI: 10.1096/Fj.201802610Rr  0.33
2019 Horbinski C, Ligon KL, Brastianos P, Huse JT, Venere M, Chang S, Buckner J, Cloughesy T, Jenkins RB, Giannini C, Nabors LB, Wen PY, Aldape KJ, Lukas RV, Galanis E, ... ... Brat DJ, et al. The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients. Neuro-Oncology. PMID 31276167 DOI: 10.1093/Neuonc/Noz119  0.403
2019 Louis DN, Wesseling P, Brandner S, Brat DJ, Ellison DW, Giangaspero F, Hattab EM, Hawkins C, Judge MJ, Kleinschmidt-DeMasters B, Komori T, McLean C, Paulus W, Perry A, Reifenberger G, et al. Data Sets for the Reporting of Tumors of the Central Nervous System. Archives of Pathology & Laboratory Medicine. PMID 31219344 DOI: 10.5858/Arpa.2018-0565-Oa  0.304
2019 Louis DN, Ellison DW, Brat DJ, Aldape K, Capper D, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, von Deimling A, Wesseling P. cIMPACT-NOW: A practical summary of diagnostic points from Round 1 updates. Brain Pathology (Zurich, Switzerland). PMID 31038238 DOI: 10.1111/Bpa.12732  0.368
2019 Yeaney GA, Brat DJ. What Every Neuropathologist Needs to Know: Update on cIMPACT-NOW. Journal of Neuropathology and Experimental Neurology. PMID 30830209 DOI: 10.1093/Jnen/Nlz012  0.371
2019 Sharma NV, Chau M, Mukherjee S, Ross J, Miller B, Zhang C, Kong J, Tucker-Burden C, Kaissi E, Reitnauer JW, Dundar B, Olson CL, Bix G, Brat DJ. Abstract 1153: Hypoxic microenvironments promote stemness and enhance the directed migration of glioma stem cells Cancer Research. 79: 1153-1153. DOI: 10.1158/1538-7445.Am2019-1153  0.369
2019 Markwell S, Ross J, Olson C, Nunez-Santana F, Arvanitis C, Mukherjee S, Brat D. TMOD-37. INTRAVITAL MONITORING DYNAMIC TUMOR MICRO-ENVIRONMENTAL EVOLUTION FOLLOWING HYPOXIA-INDUCED NECROSIS IN GLIOBLASTOMA Neuro-Oncology. 21: vi271-vi271. DOI: 10.1093/Neuonc/Noz175.1136  0.43
2018 Fritchie K, Jensch K, Moskalev EA, Caron A, Jenkins S, Link M, Brown PD, Rodriguez FJ, Guajardo A, Brat D, Velázquez Vega JE, Perry A, Wu A, Raleigh DR, Santagata S, et al. The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma. Acta Neuropathologica. PMID 30584643 DOI: 10.1007/S00401-018-1952-6  0.401
2018 Chen AS, Wardwell-Ozgo J, Shah NN, Wright D, Appin CL, Vigneswaran K, Brat DJ, Kornblum HI, Read RD. Drak/STK17A drives neoplastic glial proliferation through modulation of MRLC signaling. Cancer Research. PMID 30530503 DOI: 10.1158/0008-5472.Can-18-0482  0.341
2018 Rinaldo L, Priemer DS, Vortmeyer AO, Cohen-Gadol AA, Brat DJ, Mahajan A, Giannini C, Burns TC. Chordoma of the corpus callosum: case report. Journal of Neurosurgery. 1-7. PMID 30497142 DOI: 10.3171/2018.6.Jns181028  0.325
2018 Brat DJ, Aldape K, Colman H, Holland EC, Louis DN, Jenkins RB, Kleinschmidt-DeMasters BK, Perry A, Reifenberger G, Stupp R, von Deimling A, Weller M. cIMPACT-NOW update 3: recommended diagnostic criteria for "Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV". Acta Neuropathologica. PMID 30259105 DOI: 10.1007/S00401-018-1913-0  0.34
2018 Koehler JW, Miller AD, Miller CR, Porter B, Aldape K, Beck J, Brat D, Cornax I, Corps K, Frank C, Giannini C, Horbinski C, Huse JT, O'Sullivan MG, Rissi DR, et al. A Revised Diagnostic Classification of Canine Glioma: Towards Validation of the Canine Glioma Patient as a Naturally Occurring Preclinical Model for Human Glioma. Journal of Neuropathology and Experimental Neurology. PMID 30239918 DOI: 10.1093/Jnen/Nly085  0.389
2018 Mukherjee S, Tucker-Burden C, Kaissi E, Newsam A, Duggireddy H, Chau M, Zhang C, Diwedi B, Rupji M, Seby S, Kowalski J, Kong J, Read R, Brat DJ. CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells. Cell Reports. 23: 1651-1664. PMID 29742423 DOI: 10.1016/J.Celrep.2018.04.016  0.384
2018 Hou Y, Konen J, Brat DJ, Marcus AI, Cooper LAD. TASI: A software tool for spatial-temporal quantification of tumor spheroid dynamics. Scientific Reports. 8: 7248. PMID 29739990 DOI: 10.1038/S41598-018-25337-4  0.318
2018 Vega JEV, Brat DJ. Incorporating Advances in Molecular Pathology Into Brain Tumor Diagnostics. Advances in Anatomic Pathology. 25: 143-171. PMID 29521646 DOI: 10.1097/Pap.0000000000000186  0.412
2018 Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, et al. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nature Communications. 9: 810. PMID 29476136 DOI: 10.1038/S41467-018-02826-8  0.412
2018 Aldape K, Amin SB, Ashley DM, Barnholtz-Sloan JS, Bates AJ, Beroukhim R, Bock C, Brat DJ, Claus EB, Costello JF, de Groot JF, Finocchiaro G, French PJ, Gan HK, Griffith B, et al. Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium. Neuro-Oncology. PMID 29432615 DOI: 10.1093/Neuonc/Noy020  0.382
2018 Reinertsen E, Neill SG, Nael K, Brat DJ, Hadjipanayis CG. Meningioma With Tyrosine-Rich Crystalloids: A Case Report and Review of the Literature. International Journal of Surgical Pathology. 26: 157-160. PMID 28817996 DOI: 10.1177/1066896917727100  0.357
2018 Mukherjee S, Olson C, Brat D. Abstract 142: cdk5 inhibition promotes neurogenesis while reducing self-renewal of brain tumor stem cells Tumor Biology. DOI: 10.1158/1538-7445.Am2018-142  0.351
2018 Fritchie K, Jensch K, Jenkins S, Link M, D Brown P, Rodriguez F, Guajardo A, Brat D, Velazquez Vega J, Perry A, Wu A, Raleigh D, Santagata S, Louis D, Brastianos P, et al. RARE-08. GRADING CONSIDERATIONS FOR MENINGEAL SOLITARY FIBROUS TUMOR/HEMANGIOPERICYTOMA Neuro-Oncology. 20: vi237-vi238. DOI: 10.1093/Neuonc/Noy148.985  0.398
2018 Louis D, Brat D, Ellison D. PATH-32. BRAIN TUMOR CLASSIFICATION UPDATES FROM cIMPACT-NOW, THE CONSORTIUM TO INFORM MOLECULAR AND PRACTICAL APPROACHES TO CNS TUMOR CLASSIFICATION Neuro-Oncology. 20: vi165-vi165. DOI: 10.1093/Neuonc/Noy148.688  0.385
2017 Ross JL, Cooper LAD, Kong J, Gutman D, Williams M, Tucker-Burden C, McCrary MR, Bouras A, Kaluzova M, Dunn WD, Duong D, Hadjipanayis CG, Brat DJ. 5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins. Scientific Reports. 7: 15593. PMID 29142297 DOI: 10.1038/S41598-017-15849-W  0.4
2017 Patel SH, Poisson LM, Brat DJ, Zhou Y, Cooper L, Snuderl M, Thomas C, Franceschi AM, Griffith B, Flanders A, Golfinos JG, Chi AS, Jain R. T2-FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower Grade Gliomas: A TCGA/TCIA Project. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28751449 DOI: 10.1158/1078-0432.Ccr-17-0560  0.371
2017 Qi Q, Kang SS, Zhang S, Pham C, Fu H, Brat DJ, Ye K. Co-amplification of phosphoinositide 3-kinase enhancer A and cyclin-dependent kinase 4 triggers glioblastoma progression. Oncogene. PMID 28368413 DOI: 10.1038/Onc.2017.67  0.374
2017 Erwood AA, Velazquez-Vega JE, Neill S, Solomon DA, Butowski N, Nowlan A, Dunbar E, Brat DJ. Chordoid glioma of the third ventricle: report of a rapidly progressive case. Journal of Neuro-Oncology. PMID 28315998 DOI: 10.1007/S11060-017-2399-7  0.422
2017 Neill SG, Saxe DF, Rossi MR, Schniederjan MJ, Brat DJ. Genomic Analysis in the Practice of Surgical Neuropathology: The Emory Experience. Archives of Pathology & Laboratory Medicine. 141: 355-365. PMID 28234572 DOI: 10.5858/Arpa.2016-0276-Sai  0.356
2017 Zhang C, Mukherjee S, Tucker-Burden C, Ross JL, Chau MJ, Kong J, Brat DJ. TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3. Molecular Oncology. PMID 28100038 DOI: 10.1002/1878-0261.12034  0.364
2017 Hauenstein J, Liebenberg AP, Matthews B, O'Hare C, Thompson KS, Phillips CN, Williams JM, Rouhi O, Vega JEV, Hunter SB, Brat DJ, Olson JJ, Schniederjan MJ, Neill SG, Saxe D, et al. Comparison of Genomic Coverage Using Affymetrix OncoScan Array and Illumina TruSight Tumor 170 NGS Panel for Detection of Copy Number Abnormalities in Clinical GBM Specimens Cancer Genetics and Cytogenetics. 214: 33. DOI: 10.1016/J.Cancergen.2017.04.005  0.328
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Gregory Cairncross J, Pfister SM, Rutkowski S, et al. cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification. Brain Pathology (Zurich, Switzerland). PMID 27997995 DOI: 10.1111/Bpa.12457  0.385
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Cairncross JG, Pfister SM, Rutkowski S, et al. Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. Acta Neuropathologica. PMID 27909809 DOI: 10.1007/S00401-016-1646-X  0.391
2016 Ostrom QT, Gittleman H, Kruchko C, Louis DN, Brat DJ, Gilbert MR, Petkov VI, Barnholtz-Sloan JS. Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying). Journal of Neuro-Oncology. PMID 27418206 DOI: 10.1007/S11060-016-2217-7  0.389
2016 Halani SH, Brat DJ. Defining neoplastic diseases differently: An emerging paradigm from The Cancer Genome Atlas lower-grade gliomas project Molecular and Cellular Oncology. 3. PMID 27308595 DOI: 10.1080/23723556.2015.1074333  0.318
2016 Tanenbaum DG, Hall WA, Colbert LE, Bastien AJ, Brat DJ, Kong J, Kim S, Dwivedi B, Kowalski J, Landry JC, Yu DS. TNFRSF10C copy number variation is associated with metastatic colorectal cancer. Journal of Gastrointestinal Oncology. 7: 306-14. PMID 27284460 DOI: 10.21037/Jgo.2015.11.04  0.309
2016 Mukherjee S, Tucker-Burden C, Zhang C, Moberg K, Read R, Hadjipanayis C, Brat DJ. Drosophila Brat and human ortholog TRIM3 maintain stem cell equilibrium and suppress brain tumorigenesis by attenuating Notch nuclear transport. Cancer Research. PMID 26893479 DOI: 10.1158/0008-5472.Can-15-2299  0.366
2016 Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, ... ... Brat DJ, et al. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 164: 550-563. PMID 26824661 DOI: 10.1016/J.Cell.2015.12.028  0.356
2016 Qaddoumi I, Orisme W, Wen J, Santiago T, Gupta K, Dalton JD, Tang B, Haupfear K, Punchihewa C, Easton J, Mulder H, Boggs K, Shao Y, Rusch M, Becksfort J, ... ... Brat D, et al. Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology. Acta Neuropathologica. PMID 26810070 DOI: 10.1007/S00401-016-1539-Z  0.387
2016 Zhang CM, Brat DJ. Genomic profiling of lower-grade gliomas uncovers cohesive disease groups: implications for diagnosis and treatment. Chinese Journal of Cancer. 35: 12. PMID 26758195 DOI: 10.1186/S40880-015-0071-1  0.405
2016 Hinrichs BH, Newman S, Appin CL, Dunn W, Cooper L, Pauly R, Kowalski J, Rossi MR, Brat DJ. Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups. Acta Neuropathologica Communications. 4: 4. PMID 26757882 DOI: 10.1186/S40478-015-0270-7  0.353
2016 Stetson LC, Souza CFd, Malta TM, Sabedot TS, Ostrom Q, Liao P, Tirapelli DPdC, Neder L, Carlotti CG, Akbani R, Salama S, Poisson L, Brat D, Noushmehr H, Barnholtz-Sloan J. Abstract 780: Multi-omic profiling of gliomas reveals distinct DNA methylation changes at tumor recurrence Cancer Research. 76: 780-780. DOI: 10.1158/1538-7445.Am2016-780  0.389
2016 Zhang C, Subhas M, Carol T, Chau M, Kong J, Brat D. Abstract 2516: TRIM8 modulates stem-like cells in glioblastoma Cancer Research. 76: 2516-2516. DOI: 10.1158/1538-7445.Am2016-2516  0.379
2016 Ross J, Brat D, Hadjipanayis C, Cooper L, Wiliams M, Bouras A, Kaluzova M, Dunn W, Gutman D, Duong D, McCrary M. TMIC-23. DIFFERENTIAL EXPRESSION OF THERAPEUTIC TARGETS ACROSS TUMOR MICROENVIRONMENTS AND AT INFILTRATIVE MARGINS IN GLIOBLASTOMA Neuro-Oncology. 18: vi204-vi205. DOI: 10.1093/Neuonc/Now212.863  0.377
2016 Hauenstein JE, Liebenberg AP, Matthews BK, O'Hare CS, Thompson KS, Phillips CN, Williams JM, Vega JEV, Hunter SB, Brat DJ, Olson JJ, Schniederjan MJ, Neill SG, Rossi MR, Saxe DF. Toward Standardized Reporting and Databasing of Polyploid Tumors Cancer Genetics and Cytogenetics. 209: 289. DOI: 10.1016/J.Cancergen.2016.04.019  0.373
2015 Nahed BV, Redjal N, Brat DJ, Chi AS, Oh K, Batchelor TT, Ryken TC, Kalkanis SN, Olson JJ. Management of patients with recurrence of diffuse low grade glioma : A systematic review and evidence-based clinical practice guideline. Journal of Neuro-Oncology. PMID 26530264 DOI: 10.1007/S11060-015-1910-2  0.327
2015 Kang HB, Fan J, Lin R, Elf S, Ji Q, Zhao L, Jin L, Seo JH, Shan C, Arbiser JL, Cohen C, Brat D, Miziorko HM, Kim E, Abdel-Wahab O, et al. Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling. Molecular Cell. PMID 26145173 DOI: 10.1016/J.Molcel.2015.05.037  0.374
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.333
2015 Appin CL, Brat DJ. Biomarker-driven diagnosis of diffuse gliomas Molecular Aspects of Medicine. 45: 87-96. PMID 26004297 DOI: 10.1016/J.Mam.2015.05.002  0.373
2015 Zhang S, Qi Q, Chan CB, Zhou W, Chen J, Luo HR, Appin C, Brat DJ, Ye K. Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity. Cell Death and Differentiation. PMID 26001218 DOI: 10.1038/Cdd.2015.66  0.325
2015 Lym RL, Ostrom QT, Kruchko C, Couce M, Brat DJ, Louis DN, Barnholtz-Sloan JS. Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011. Journal of Neuro-Oncology. 123: 43-51. PMID 25864099 DOI: 10.1007/S11060-015-1775-4  0.411
2015 Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, et al. Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution. Genome Research. 25: 316-27. PMID 25650244 DOI: 10.1101/Gr.180612.114  0.416
2015 Cooper LA, Kong J, Gutman DA, Dunn WD, Nalisnik M, Brat DJ. Novel genotype-phenotype associations in human cancers enabled by advanced molecular platforms and computational analysis of whole slide images. Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 366-76. PMID 25599536 DOI: 10.1038/Labinvest.2014.153  0.328
2015 Chen K, Yang D, Li X, Sun B, Song F, Cao W, Brat DJ, Gao Z, Li H, Liang H, Zhao Y, Zheng H, Li M, Buckner J, Patterson SD, et al. Mutational landscape of gastric adenocarcinoma in Chinese: implications for prognosis and therapy. Proceedings of the National Academy of Sciences of the United States of America. 112: 1107-12. PMID 25583476 DOI: 10.1073/Pnas.1422640112  0.344
2015 Zhu S, Kisiel W, Lu YJ, Petersen LC, Ndungu JM, Moore TW, Parker ET, Sun A, Sarkaria JN, Snyder JP, Liotta DC, Brat DJ, El-Rayes BF, Shoji M. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. Journal of Drug Targeting. 23: 257-65. PMID 25510254 DOI: 10.3109/1061186X.2014.988217  0.333
2015 Appin CL, Brat DJ. Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis. Advances in Anatomic Pathology. 22: 50-8. PMID 25461780 DOI: 10.1097/Pap.0000000000000048  0.36
2015 Mishra A, Brat DJ, Verma M. P53 tumor suppression network in cancer epigenetics. Methods in Molecular Biology (Clifton, N.J.). 1238: 597-605. PMID 25421682 DOI: 10.1007/978-1-4939-1804-1_31  0.332
2015 Mishra A, Kong J, Brat DJ. Abstract LB-029: Signal transduction in EGFR-amplified and NFKBIA-deleted human gliomas Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-029  0.31
2015 Chau MJ, McCrary MR, Mukherjee S, Brat DJ. Abstract 5217: Microenvironmental influences on glioma stem cell migration Cancer Research. 75: 5217-5217. DOI: 10.1158/1538-7445.Am2015-5217  0.325
2015 McCrary MR, Gutman D, Dunn W, Kaluzova M, Bouros A, Williams M, Zhang X, Cooper LA, Hadjipanayis CG, Brat DJ. Abstract 415: Differential expression of therapeutic targets across tumor micro-environments and at infiltrative margins in glioblastoma Cancer Research. 75: 415-415. DOI: 10.1158/1538-7445.Am2015-415  0.423
2015 Barthel FP, Ceccarelli M, Malta TM, Sabedot TS, Salama SR, Pagnotta SM, Murray BA, Morozova O, Newton Y, Brat DJ, Cherniack AD, Zhang H, Poisson L, Cooper L, Rabadan R, et al. GENO-06A PAN-GLIOMA CHARACTERIZATION OF GENOMIC, EPIGENOMIC AND TRANSCRIPTOMIC ACTIVITIES REVEALS NOVEL RELATIONSHIPS BETWEEN HISTOLOGICAL SUBTYPES AND MOLECULAR SIGNATURES Neuro-Oncology. 17: v92.2-v92. DOI: 10.1093/Neuonc/Nov215.06  0.38
2015 Ostrom Q, Brat D, Cooper L, Gutman D, Barnholtz-Sloan J. EPID-06AGE-SPECIFIC FEATURES OF LOW AND HIGH-GRADE DIFFUSE GLIOMAS BY IDH MUTATION STATUS Neuro-Oncology. 17: v79.2-v79. DOI: 10.1093/Neuonc/Nov213.06  0.315
2015 Chau M, Mukherjee S, Kola R, Brat D. Csig-02Gbm Stem Cell Migration And The Hypoxic Microenvironment Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov210.02  0.338
2014 Shan C, Elf S, Ji Q, Kang HB, Zhou L, Hitosugi T, Jin L, Lin R, Zhang L, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, ... ... Brat DJ, et al. Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth. Molecular Cell. 55: 552-65. PMID 25042803 DOI: 10.1016/J.Molcel.2014.06.020  0.338
2014 Chen G, Kong J, Tucker-Burden C, Anand M, Rong Y, Rahman F, Moreno CS, Van Meir EG, Hadjipanayis CG, Brat DJ. Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma. Cancer Research. 74: 4536-48. PMID 24947043 DOI: 10.1158/0008-5472.Can-13-3703  0.375
2014 Ostrom QT, Chen Y, M de Blank P, Ondracek A, Farah P, Gittleman H, Wolinsky Y, Kruchko C, Cohen ML, Brat DJ, Barnholtz-Sloan JS. The descriptive epidemiology of atypical teratoid/rhabdoid tumors in the United States, 2001-2010. Neuro-Oncology. 16: 1392-9. PMID 24847086 DOI: 10.1093/Neuonc/Nou090  0.4
2014 Guan X, Vengoechea J, Zheng S, Sloan AE, Chen Y, Brat DJ, O'Neill BP, de Groot J, Yust-Katz S, Yung WK, Cohen ML, Aldape KD, Rosenfeld S, Verhaak RG, Barnholtz-Sloan JS. Molecular subtypes of glioblastoma are relevant to lower grade glioma. Plos One. 9: e91216. PMID 24614622 DOI: 10.1371/Journal.Pone.0091216  0.368
2014 Appin CL, Brat DJ. Molecular genetics of gliomas. Cancer Journal (Sudbury, Mass.). 20: 66-72. PMID 24445767 DOI: 10.1097/Ppo.0000000000000020  0.351
2014 Zerrouqi A, Pyrzynska B, Brat DJ, Van Meir EG. P14ARF suppresses tumor-induced thrombosis by regulating the tissue factor pathway. Cancer Research. 74: 1371-8. PMID 24398474 DOI: 10.1158/0008-5472.Can-13-1951  0.402
2014 Huse JT, Wallace M, Aldape KD, Berger MS, Bettegowda C, Brat DJ, Cahill DP, Cloughesy T, Haas-Kogan DA, Marra M, Miller CR, Nelson SJ, Salama SR, Soffietti R, Wen PY, et al. Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop. Neuro-Oncology. 16: 173-8. PMID 24305708 DOI: 10.1093/Neuonc/Not229  0.371
2014 Qi Q, Liu X, Brat DJ, Ye K. Merlin sumoylation is required for its tumor suppressor activity. Oncogene. 33: 4893-903. PMID 24166499 DOI: 10.1038/Onc.2013.438  0.375
2014 Mukherjee S, Chen G, Anand M, Kong J, Tucker-Burden C, Rong Y, Rahman F, Moreno C, Meir EV, Hadjipanayis C, Brat D. Abstract LB-50: TRIM3, the human homolog of Drosophila Brat, is a tumor suppressor that regulates asymmetric cell division (ACD) in glioblastoma stem cells Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-50  0.374
2014 Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Sloan AE, Cohen ML, Meir EGV, Scarpace L, Laird PW, Weinstein JN, Lander E, et al. Abstract 984: Alteration of the p53 pathway is associated with subclonal tumor progression in glioblastoma Cancer Research. 74: 984-984. DOI: 10.1158/1538-7445.Am2014-984  0.379
2014 Verhaak RGW, Cooper LAD, Salama SS, Aldape K, Yung WKA, Brat DJ. Abstract 936: Comprehensive and integrative genomic characterization of diffuse lower grade gliomas Cancer Research. 74: 936-936. DOI: 10.1158/1538-7445.Am2014-936  0.358
2014 Mukherjee S, Chen G, Kong J, Brat D. SC-21 * TRIM3, A HUMAN ORTHOLOG OF DROSOPHILA BRAT, MAINTAINS ASYMMETRIC CELL DIVISION OF GLIOMA STEM CELLS BY REGULATING c-MYC AND NOTCH1 Neuro-Oncology. 16: v201-v201. DOI: 10.1093/Neuonc/Nou275.21  0.32
2014 Cordova JS, Liang Z, Holder CA, Appin C, Schreibmann E, Bian X, Brat D, Shu H, Olson J, Maudsley A, Shim H, Hadjipanayis C. Ni-15Use Of Volumetric Mr Spectroscopic Imaging And 5-Ala Fluorescence-Guided Surgery For Resection Of Glioblastoma Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou264.14  0.393
2014 Yung WKA, Verhaak R, Cooper L, Salama S, Aldape K, Brat D. Ge-41Comprehensive And Integrative Genomic Characterization Of Diffuse Lower Grade Gliomas Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou256.40  0.348
2014 Kim H, Zheng S, Amini S, Virk S, Mikkelsen T, Brat D, Sougnez C, Muller F, Hu J, Sloan A, Cohen M, Van Meir E, Scarpace L, Lander E, Gabriel S, et al. GE-17 * ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA Neuro-Oncology. 16: v100-v100. DOI: 10.1093/Neuonc/Nou256.17  0.394
2014 Mishra A, Kong J, Brat D. Cs-23Defining The Networks And Intersection Of Egfr Amplification And Nfkbia Deletion In Human Glioma Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou242.23  0.314
2014 Brat DJ. Integrative Genomic Characterization Of Lower Grade Gliomas Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou206.11  0.331
2013 Kong J, Cooper LA, Wang F, Gao J, Teodoro G, Scarpace L, Mikkelsen T, Schniederjan MJ, Moreno CS, Saltz JH, Brat DJ. Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates. Plos One. 8: e81049. PMID 24236209 DOI: 10.1371/Journal.Pone.0081049  0.364
2013 Rutledge WC, Kong J, Gao J, Gutman DA, Cooper LA, Appin C, Park Y, Scarpace L, Mikkelsen T, Cohen ML, Aldape KD, McLendon RE, Lehman NL, Miller CR, Schniederjan MJ, ... ... Brat DJ, et al. Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4951-60. PMID 23864165 DOI: 10.1158/1078-0432.Ccr-13-0551  0.393
2013 Schniederjan MJ, Alghamdi S, Castellano-Sanchez A, Mazewski C, Brahma B, Brat DJ, Brathwaite CD, Janss AJ. Diffuse leptomeningeal neuroepithelial tumor: 9 pediatric cases with chromosome 1p/19q deletion status and IDH1 (R132H) immunohistochemistry. The American Journal of Surgical Pathology. 37: 763-71. PMID 23588371 DOI: 10.1097/Pas.0B013E31827Bf4Cc  0.372
2013 Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, et al. PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma. Brain Pathology (Zurich, Switzerland). 23: 565-73. PMID 23438035 DOI: 10.1111/Bpa.12043  0.36
2013 Pasquel FJ, Vincentelli C, Brat DJ, Oyesiku NM, Ioachimescu AG. Pituitary carcinoma in situ. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 19: e69-73. PMID 23425649 DOI: 10.4158/Ep12351.Cr  0.342
2013 Gutman DA, Cooper LA, Hwang SN, Holder CA, Gao J, Aurora TD, Dunn WD, Scarpace L, Mikkelsen T, Jain R, Wintermark M, Jilwan M, Raghavan P, Huang E, Clifford RJ, ... ... Brat DJ, et al. MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set. Radiology. 267: 560-9. PMID 23392431 DOI: 10.1148/Radiol.13120118  0.408
2013 Appin CL, Gao J, Chisolm C, Torian M, Alexis D, Vincentelli C, Schniederjan MJ, Hadjipanayis C, Olson JJ, Hunter S, Hao C, Brat DJ. Glioblastoma with oligodendroglioma component (GBM-O): molecular genetic and clinical characteristics. Brain Pathology (Zurich, Switzerland). 23: 454-61. PMID 23289977 DOI: 10.1111/Bpa.12018  0.346
2013 Jain R, Poisson L, Narang J, Gutman D, Scarpace L, Hwang SN, Holder C, Wintermark M, Colen RR, Kirby J, Freymann J, Brat DJ, Jaffe C, Mikkelsen T. Genomic mapping and survival prediction in glioblastoma: molecular subclassification strengthened by hemodynamic imaging biomarkers. Radiology. 267: 212-20. PMID 23238158 DOI: 10.1148/Radiol.12120846  0.316
2013 Poole Perry LJ, Jakobiec FA, Zakka FR, Reichel E, Herwig MC, Perry A, Brat DJ, Grossniklaus HE. Reactive retinal astrocytic tumors (so-called vasoproliferative tumors): histopathologic, immunohistochemical, and genetic studies of four cases. American Journal of Ophthalmology. 155: 593-608.e1. PMID 23219067 DOI: 10.1016/J.Ajo.2012.09.002  0.38
2013 Joseph NM, Phillips J, Dahiya S, M Felicella M, Tihan T, Brat DJ, Perry A. Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variants. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 26: 315-26. PMID 23041832 DOI: 10.1038/Modpathol.2012.173  0.374
2013 He K, Qi Q, Chan C, Xiao G, Liu X, Tucker-Burden C, Wang L, Mao H, Lu X, McDonald FE, Luo H, Fan Q, Weiss WA, Sun S, Brat DJ, et al. Abstract 5683: Blockade of glioma proliferation via allosteric inhibition of JAK2. Cancer Research. 73: 5683-5683. DOI: 10.1158/1538-7445.Am2013-5683  0.385
2013 Kim H, Zheng S, Amini SS, Virk S, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Sloan AE, Cohen ML, Meir EGV, Scarpace L, Laird PW, Weinstein JN, Lander ES, et al. Abstract B130: The intratumoral heterogeneity of glioblastoma suggests a pivotal role for clonal evolution. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B130  0.356
2012 Singh D, Chan JM, Zoppoli P, Niola F, Sullivan R, Castano A, Liu EM, Reichel J, Porrati P, Pellegatta S, Qiu K, Gao Z, Ceccarelli M, Riccardi R, Brat DJ, et al. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science (New York, N.Y.). 337: 1231-5. PMID 22837387 DOI: 10.1126/Science.1220834  0.342
2012 Anand M, Brat DJ. Oncogenic regulation of tissue factor and thrombosis in cancer. Thrombosis Research. 129: S46-9. PMID 22682132 DOI: 10.1016/S0049-3848(12)70015-4  0.39
2012 Ioachimescu AG, Eiland L, Chhabra VS, Mastrogianakis GM, Schniederjan MJ, Brat D, Pileggi AV, Oyesiku NM. Silent corticotroph adenomas: Emory University cohort and comparison with ACTH-negative nonfunctioning pituitary adenomas. Neurosurgery. 71: 296-304. PMID 22517250 DOI: 10.1227/Neu.0B013E318257C1F0  0.348
2012 Munson JM, Fried L, Rowson SA, Bonner MY, Karumbaiah L, Diaz B, Courtneidge SA, Knaus UG, Brat DJ, Arbiser JL, Bellamkonda RV. Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma. Science Translational Medicine. 4: 127ra36. PMID 22461640 DOI: 10.1126/Scitranslmed.3003016  0.334
2012 Cooper LA, Gutman DA, Chisolm C, Appin C, Kong J, Rong Y, Kurc T, Van Meir EG, Saltz JH, Moreno CS, Brat DJ. The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. The American Journal of Pathology. 180: 2108-19. PMID 22440258 DOI: 10.1016/J.Ajpath.2012.01.040  0.339
2012 Tucker-Burden C, Chappa P, Krishnamoorthy M, Gerwe BA, Scharer CD, Heimburg-Molinaro J, Harris W, Usta SN, Eilertson CD, Hadjipanayis CG, Stice SL, Brat DJ, Nash RJ. Lectins identify glycan biomarkers on glioblastoma-derived cancer stem cells. Stem Cells and Development. 21: 2374-86. PMID 22435486 DOI: 10.1089/Scd.2011.0369  0.382
2012 Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG. P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3. The Journal of Clinical Investigation. 122: 1283-95. PMID 22378045 DOI: 10.1172/Jci38596  0.432
2012 Vincentelli C, Hwang SN, Holder CA, Brat DJ. The use of neuroimaging to guide the histologic diagnosis of central nervous system lesions. Advances in Anatomic Pathology. 19: 97-107. PMID 22313837 DOI: 10.1097/Pap.0B013E318248B747  0.319
2012 Cooper LA, Kong J, Gutman DA, Wang F, Gao J, Appin C, Cholleti S, Pan T, Sharma A, Scarpace L, Mikkelsen T, Kurc T, Moreno CS, Brat DJ, Saltz JH. Integrated morphologic analysis for the identification and characterization of disease subtypes. Journal of the American Medical Informatics Association : Jamia. 19: 317-23. PMID 22278382 DOI: 10.1136/Amiajnl-2011-000700  0.343
2012 Martin SE, Brat DJ, Vance GH, Stohler R, Choi H, Douglas-Akinwande AC, Hattab EM. Glioblastoma occurring at the site of a previous medulloblastoma following a 5-year remission period. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 32: 543-50. PMID 22151431 DOI: 10.1111/J.1440-1789.2011.01277.X  0.42
2012 Shim H, Voloschin AD, Wei L, Hwang SN, Miller AH, Guo Y, Brat D, Holder CA, Read WL, Kopcewicz K, Harvey RD, Barker P, Shu HG, Hu XP, Olson JJ. Using proton MRSI to predict response to vorinostat treatment in recurrent GBM. Journal of Clinical Oncology. 30: 3055-3055. DOI: 10.1200/Jco.2012.30.15_Suppl.3055  0.395
2012 Shim H, Wei L, Hwang SN, Miller AH, Guo Y, Holder CA, Read W, Kopcewicz K, Voloschin A, Brat DJ, Hu XP, Shu HG, Barker P, Olson JJ. Abstract LB-159: Using proton MRSI to predict response of Vorinostat treatment in recurrent GBM Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-159  0.41
2011 Putluri N, Shojaie A, Vasu VT, Vareed SK, Nalluri S, Putluri V, Thangjam GS, Panzitt K, Tallman CT, Butler C, Sana TR, Fischer SM, Sica G, Brat DJ, Shi H, et al. Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression. Cancer Research. 71: 7376-86. PMID 21990318 DOI: 10.1158/0008-5472.Can-11-1154  0.303
2011 Kong J, Cooper LA, Wang F, Gutman DA, Gao J, Chisolm C, Sharma A, Pan T, Van Meir EG, Kurc TM, Moreno CS, Saltz JH, Brat DJ. Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes. Ieee Transactions On Bio-Medical Engineering. 58: 3469-74. PMID 21947516 DOI: 10.1109/Tbme.2011.2169256  0.341
2011 Atif F, Sayeed I, Yousuf S, Ishrat T, Hua F, Wang J, Brat DJ, Stein DG. Progesterone inhibits the growth of human neuroblastoma: in vitro and in vivo evidence. Molecular Medicine (Cambridge, Mass.). 17: 1084-94. PMID 21695351 DOI: 10.2119/Molmed.2010.00255  0.316
2011 Cohen KJ, Pollack IF, Zhou T, Buxton A, Holmes EJ, Burger PC, Brat DJ, Rosenblum MK, Hamilton RL, Lavey RS, Heideman RL. Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group. Neuro-Oncology. 13: 317-23. PMID 21339192 DOI: 10.1093/Neuonc/Noq191  0.306
2011 Ellison DW, Dalton J, Kocak M, Nicholson SL, Fraga C, Neale G, Kenney AM, Brat DJ, Perry A, Yong WH, Taylor RE, Bailey S, Clifford SC, Gilbertson RJ. Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups. Acta Neuropathologica. 121: 381-96. PMID 21267586 DOI: 10.1007/S00401-011-0800-8  0.309
2011 Egan KM, Thompson RC, Nabors LB, Olson JJ, Brat DJ, Larocca RV, Brem S, Moots PL, Madden MH, Browning JE, Ann Chen Y. Cancer susceptibility variants and the risk of adult glioma in a US case-control study. Journal of Neuro-Oncology. 104: 535-42. PMID 21203894 DOI: 10.1007/S11060-010-0506-0  0.385
2011 Raore B, Schniederjan M, Prabhu R, Brat DJ, Shu HK, Olson JJ. Metastasis infiltration: an investigation of the postoperative brain-tumor interface. International Journal of Radiation Oncology, Biology, Physics. 81: 1075-80. PMID 20971574 DOI: 10.1016/J.Ijrobp.2010.07.034  0.396
2011 Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Lyons-Weiler MA, LaFramboise WA, Burger PC, Brat DJ, Rosenblum MK, Holmes EJ, Zhou T, Jakacki RI. IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 27: 87-94. PMID 20725730 DOI: 10.1007/S00381-010-1264-1  0.337
2011 Egan KM, Nabors LB, Olson JJ, Browning JE, Madden MH, Chen YA, Brem S, Brat DJ, Sontheimer H, Tran ND, Thompson RC. Abstract 876: Genetic variation in the voltage-gated chloride channel family members CLCN2 and CLCN3 in relation to glioma risk and outcome Cancer Research. 71: 876-876. DOI: 10.1158/1538-7445.Am2011-876  0.32
2011 Madden MH, Thompson RC, Nabors LB, Olson JJ, Browning JE, Chen YA, Brat DJ, Egan KM. Abstract 874: Genetic variation in the NOTCH stem cell signaling network in relation to risk of adult-onset glioma Cancer Research. 71: 874-874. DOI: 10.1158/1538-7445.Am2011-874  0.326
2011 Chen G, Rong Y, Rahman F, Tucker-Burden C, Hadjipanayis C, Meir EGV, Brat DJ. Abstract 3305: Trim3, the human homolog of Drosophila brat, regulates asymmetric division in glioblastoma stem cells Cancer Research. 71: 3305-3305. DOI: 10.1158/1538-7445.Am2011-3305  0.384
2010 Cooper LA, Gutman DA, Long Q, Johnson BA, Cholleti SR, Kurc T, Saltz JH, Brat DJ, Moreno CS. The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas. Plos One. 5: e12548. PMID 20838435 DOI: 10.1371/Journal.Pone.0012548  0.418
2010 Cooper LA, Kong J, Gutman DA, Wang F, Cholleti SR, Pan TC, Widener PM, Sharma A, Mikkelsen T, Flanders AE, Rubin DL, Van Meir EG, Kurc TM, Moreno CS, Brat DJ, et al. An integrative approach for in silico glioma research. Ieee Transactions On Bio-Medical Engineering. 57: 2617-21. PMID 20656651 DOI: 10.1109/Tbme.2010.2060338  0.351
2010 Pollack IF, Hamilton RL, Burger PC, Brat DJ, Rosenblum MK, Murdoch GH, Nikiforova MN, Holmes EJ, Zhou T, Cohen KJ, Jakacki RI. Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children's Oncology Group. Journal of Neuro-Oncology. 99: 155-63. PMID 20607350 DOI: 10.1007/S11060-010-0297-3  0.415
2010 Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Nikiforov YE, Lyons-Weiler MA, LaFramboise WA, Burger PC, Brat DJ, Rosenblum MK, Gilles FH, Yates AJ, Zhou T, Cohen KJ, Finlay JL, et al. Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group. Pediatric Blood & Cancer. 55: 1066-71. PMID 20589656 DOI: 10.1002/Pbc.22634  0.362
2010 Yoon Y, Mohs A, Liang Z, Mancini MC, Lee D, Chen GZ, Brat DJ, Chen AY, Nie S, Shim H. Abstract 2257: Optical imaging guidance of tumor resection margin for head and neck cancer Cancer Research. 70: 2257-2257. DOI: 10.1158/1538-7445.Am10-2257  0.406
2010 Moreno CS, Cooper L, Cholleti SR, Gutman D, Kurk T, Brat DJ, Saltz JH. Abstract 113: The TCGA proneural subtype predicts improved clinical outcome for low-grade oligodendrogliomas Cancer Research. 70: 113-113. DOI: 10.1158/1538-7445.Am10-113  0.398
2010 Putluri N, Vasu VT, Shojaie A, Thangjam GS, Vareed SK, Putluri V, Butler C, Giri JG, Park MA, Ponnala R, Sana TR, Fischer SM, Sica G, Brat DJ, Shi H, et al. Abstract A52: Metabolomic profiling reveals impaired xenobiotic metabolism in bladder cancer Cancer Epidemiology, Biomarkers & Prevention. 19. DOI: 10.1158/1055-9965.Disp-10-A52  0.339
2009 Bhatia B, Northcott PA, Hambardzumyan D, Govindarajan B, Brat DJ, Arbiser JL, Holland EC, Taylor MD, Kenney AM. Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization. Cancer Research. 69: 7224-34. PMID 19738049 DOI: 10.1158/0008-5472.Can-09-1299  0.331
2009 Schniederjan MJ, Shehata B, Brat DJ, Esiashvili N, Janss AJ. De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system. Pediatric Blood & Cancer. 53: 1352-4. PMID 19711436 DOI: 10.1002/Pbc.22214  0.356
2009 Rong Y, Belozerov VE, Tucker-Burden C, Chen G, Durden DL, Olson JJ, Van Meir EG, Mackman N, Brat DJ. Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity. Cancer Research. 69: 2540-9. PMID 19276385 DOI: 10.1158/0008-5472.Can-08-1547  0.328
2009 Sangoi AR, Dulai MS, Beck AH, Brat DJ, Vogel H. Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation. The American Journal of Surgical Pathology. 33: 669-81. PMID 19194275 DOI: 10.1097/Pas.0B013E318194C566  0.359
2009 Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG. Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. Cancer Research. 69: 1212-20. PMID 19176395 DOI: 10.1158/0008-5472.Can-08-1166  0.376
2009 Liu Z, Oh SM, Okada M, Liu X, Cheng D, Peng J, Brat DJ, Sun SY, Zhou W, Gu W, Ye K. Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. Molecular Biology of the Cell. 20: 757-68. PMID 19037095 DOI: 10.1091/Mbc.E08-09-0983  0.356
2009 Horbinski C, Dacic S, McLendon RE, Cieply K, Datto M, Brat DJ, Chu CT. Chordoid glioma: a case report and molecular characterization of five cases. Brain Pathology (Zurich, Switzerland). 19: 439-48. PMID 18652591 DOI: 10.1111/J.1750-3639.2008.00196.X  0.381
2008 McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis GM, Olson JJ, Mikkelsen T, Lehman N, Aldape K, Yung WKA, Bogler O, Weinstein JN, VandenBerg S, Berger M, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature. 455: 1061-1068. PMID 18772890 DOI: 10.1038/Nature07385  0.328
2008 Brat DJ, Prayson RA, Ryken TC, Olson JJ. Diagnosis of malignant glioma: role of neuropathology. Journal of Neuro-Oncology. 89: 287-311. PMID 18712282 DOI: 10.1007/S11060-008-9618-1  0.347
2008 Rodriguez FJ, Scheithauer BW, Roncaroli F, Silva AI, Kovacs K, Brat DJ, Jin L. Galectin-3 expression is ubiquitous in tumors of the sellar region, nervous system, and mimics: an immunohistochemical and RT-PCR study. The American Journal of Surgical Pathology. 32: 1344-52. PMID 18670355 DOI: 10.1097/Pas.0B013E3181694F41  0.401
2008 Brat DJ, Parisi JE, Kleinschmidt-DeMasters BK, Yachnis AT, Montine TJ, Boyer PJ, Powell SZ, Prayson RA, McLendon RE. Surgical neuropathology update: a review of changes introduced by the WHO classification of tumours of the central nervous system, 4th edition. Archives of Pathology & Laboratory Medicine. 132: 993-1007. PMID 18517285 DOI: 10.1043/1543-2165(2008)132[993:Snuaro]2.0.Co;2  0.392
2008 Parisi JE, Miller DV, Boyer PJ, Brat DJ, Cochran EJ, Cohen ML, Demasters BK, Dolinak D, McComb RD, McLendon RE, Powell SZ, Prayson RA, Vinters HV, Yachnis AT. Protocol for the examination of specimens from patients with tumors of the brain/spinal cord. Archives of Pathology & Laboratory Medicine. 132: 907-12. PMID 18517271 DOI: 10.1043/1543-2165(2008)132[907:Pfteos]2.0.Co;2  0.31
2008 Tehrani M, Friedman TM, Olson JJ, Brat DJ. Intravascular thrombosis in central nervous system malignancies: a potential role in astrocytoma progression to glioblastoma. Brain Pathology (Zurich, Switzerland). 18: 164-71. PMID 18093251 DOI: 10.1111/J.1750-3639.2007.00108.X  0.314
2007 Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Stemmer-Rachamimov AO, Rachamimov AS, et al. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Research. 67: 9398-406. PMID 17909049 DOI: 10.1158/0008-5472.Can-07-1063  0.321
2007 Post DE, Sandberg EM, Kyle MM, Devi NS, Brat DJ, Xu Z, Tighiouart M, Van Meir EG. Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4. Cancer Research. 67: 6872-81. PMID 17638898 DOI: 10.1158/0008-5472.Can-06-3244  0.331
2007 Brat DJ, Scheithauer BW, Fuller GN, Tihan T. Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. Brain Pathology (Zurich, Switzerland). 17: 319-24. PMID 17598825 DOI: 10.1111/J.1750-3639.2007.00082.X  0.312
2007 Brat DJ, Shehata BM, Castellano-Sanchez AA, Hawkins C, Yost RB, Greco C, Mazewski C, Janss A, Ohgaki H, Perry A. Congenital glioblastoma: a clinicopathologic and genetic analysis. Brain Pathology (Zurich, Switzerland). 17: 276-81. PMID 17465990 DOI: 10.1111/J.1750-3639.2007.00071.X  0.406
2007 Tumialán LM, Brat DJ, Fountain AJ, Barrow DL. An astroblastoma mimicking a cavernous malformation: case report. Neurosurgery. 60: E569-70; discussion . PMID 17327764 DOI: 10.1227/01.Neu.0000255336.80285.70  0.332
2007 Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, Rooijen NV, Stemmer-Rachamimov AO, Hochberg FH, et al. Erratum: Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses (Cancer Research (2007) 67, (9398-9406)) Cancer Research. 67. DOI: 10.1158/0008-5472.Can-67-22-Cor  0.329
2007 Tehrani M, Friedman TM, Olson JJ, Brat DJ. Intravascular thrombosis is more frequent in glioblastoma than other central nervous system malignancies: 47.4 Journal of Neuropathology and Experimental Neurology. 66: 427. DOI: 10.1097/01.Jnen.0000268838.74735.1B  0.318
2007 Tehrani M, Friedman TM, Olson JJ, Brat DJ. Intravascular thrombosis is more frequent in glioblastoma than other central nervous system malignancies The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A26-C  0.318
2006 Kang SH, Cho HT, Devi S, Zhang Z, Escuin D, Liang Z, Mao H, Brat DJ, Olson JJ, Simons JW, Lavallee TM, Giannakakou P, Van Meir EG, Shim H. Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model. Cancer Research. 66: 11991-7. PMID 17178898 DOI: 10.1158/0008-5472.Can-06-1320  0.396
2006 Khwaja FW, Duke-Cohan JS, Brat DJ, Van Meir EG. Attractin is elevated in the cerebrospinal fluid of patients with malignant astrocytoma and mediates glioma cell migration. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6331-6. PMID 17085642 DOI: 10.1158/1078-0432.Ccr-06-1296  0.316
2006 Rong Y, Durden DL, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. Journal of Neuropathology and Experimental Neurology. 65: 529-39. PMID 16783163 DOI: 10.1097/00005072-200606000-00001  0.405
2006 Brat DJ. The elusive origin of chordoid glioma. Archives of Pathology & Laboratory Medicine. 130: 437-8. PMID 16594734 DOI: 10.1043/1543-2165(2006)130[437:Teoocg]2.0.Co;2  0.332
2006 Coleman KE, Brat DJ, Cotsonis GA, Lawson D, Cohen C. Proliferation (MIB-1 expression) in oligodendrogliomas: assessment of quantitative methods and prognostic significance. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 14: 109-14. PMID 16540741 DOI: 10.1097/01.Pai.0000144557.31747.B9  0.305
2005 Dhall SS, Tumialán LM, Brat DJ, Barrow DL. Spinal intradural clear cell meningioma following resection of a suprasellar clear cell meningioma. Case report and recommendations for management. Journal of Neurosurgery. 103: 559-63. PMID 16235691 DOI: 10.3171/Jns.2005.103.3.0559  0.342
2005 Gupta M, Djalilvand A, Brat DJ. Clarifying the diffuse gliomas: an update on the morphologic features and markers that discriminate oligodendroglioma from astrocytoma. American Journal of Clinical Pathology. 124: 755-68. PMID 16203285 DOI: 10.1309/6Jnx-4Pa6-0Tq5-U5Vg  0.369
2005 Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ, Van Meir EG. Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro-Oncology. 7: 134-53. PMID 15831232 DOI: 10.1215/S1152851704001115  0.304
2005 Kaur B, Brat DJ, Devi NS, Van Meir EG. Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor. Oncogene. 24: 3632-42. PMID 15782143 DOI: 10.1038/Sj.Onc.1208317  0.357
2005 Rong Y, Post DE, Pieper RO, Durden DL, Van Meir EG, Brat DJ. PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. Cancer Research. 65: 1406-13. PMID 15735028 DOI: 10.1158/0008-5472.Can-04-3376  0.346
2005 Govindarajan B, Brat DJ, Csete M, Martin WD, Murad E, Litani K, Cohen C, Cerimele F, Nunnelley M, Lefkove B, Yamamoto T, Lee C, Arbiser JL. Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain. The Journal of Biological Chemistry. 280: 5870-4. PMID 15576369 DOI: 10.1074/Jbc.M411768200  0.322
2004 Phuphanich S, Brat DJ, Olson JJ. Delivery systems and molecular targets of mechanism-based therapies for GBM. Expert Review of Neurotherapeutics. 4: 649-63. PMID 15853584 DOI: 10.1586/14737175.4.4.649  0.386
2004 Kaur B, Tan C, Brat DJ, Post DE, Van Meir EG. Genetic and hypoxic regulation of angiogenesis in gliomas. Journal of Neuro-Oncology. 70: 229-43. PMID 15674480 DOI: 10.1007/S11060-004-2752-5  0.386
2004 Post DE, Devi NS, Li Z, Brat DJ, Kaur B, Nicholson A, Olson JJ, Zhang Z, Van Meir EG. Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8603-12. PMID 15623644 DOI: 10.1158/1078-0432.Ccr-04-1432  0.413
2004 Fan X, Mikolaenko I, Elhassan I, Ni X, Wang Y, Ball D, Brat DJ, Perry A, Eberhart CG. Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Research. 64: 7787-93. PMID 15520184 DOI: 10.1158/0008-5472.Can-04-1446  0.415
2004 Stone AR, Bobo W, Brat DJ, Devi NS, Van Meir EG, Vertino PM. Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma. The American Journal of Pathology. 165: 1151-61. PMID 15466382 DOI: 10.1016/S0002-9440(10)63376-7  0.37
2004 Junge CE, Lee CJ, Hubbard KB, Zhang Z, Olson JJ, Hepler JR, Brat DJ, Traynelis SF. Protease-activated receptor-1 in human brain: localization and functional expression in astrocytes. Experimental Neurology. 188: 94-103. PMID 15191806 DOI: 10.1016/J.Expneurol.2004.02.018  0.316
2004 Bellail AC, Hunter SB, Brat DJ, Tan C, Van Meir EG. Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion. The International Journal of Biochemistry & Cell Biology. 36: 1046-69. PMID 15094120 DOI: 10.1016/J.Biocel.2004.01.013  0.363
2004 Ulm AJ, Yachnis AT, Brat DJ, Rhoton AL. Pituicytoma: report of two cases and clues regarding histogenesis. Neurosurgery. 54: 753-7; discussion 75. PMID 15028154 DOI: 10.1227/01.Neu.0000108983.50966.B7  0.38
2004 Brat DJ, Van Meir EG. Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 397-405. PMID 14990981 DOI: 10.1038/Labinvest.3700070  0.339
2004 Brat DJ, Castellano-Sanchez AA, Hunter SB, Pecot M, Cohen C, Hammond EH, Devi SN, Kaur B, Van Meir EG. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Research. 64: 920-7. PMID 14871821 DOI: 10.1158/0008-5472.Can-03-2073  0.359
2004 Rajaram V, Leuthardt EC, Singh PK, Ojemann JG, Brat DJ, Prayson RA, Perry A. 9p21 and 13q14 dosages in ependymomas. A clinicopathologic study of 101 cases. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 17: 9-14. PMID 14631364 DOI: 10.1038/Modpathol.3800029  0.393
2003 Hunter SB, Brat DJ, Olson JJ, Von Deimling A, Zhou W, Van Meir EG. Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review). International Journal of Oncology. 23: 857-69. PMID 12963964 DOI: 10.3892/Ijo.23.4.857  0.421
2003 Hill C, Hunter SB, Brat DJ. Genetic markers in glioblastoma: prognostic significance and future therapeutic implications. Advances in Anatomic Pathology. 10: 212-7. PMID 12826827 DOI: 10.1097/00125480-200307000-00004  0.369
2003 Castellano-Sanchez AA, Ohgaki H, Yokoo H, Scheithauer BW, Burger PC, Hamilton RL, Finkelstein SD, Brat DJ. Granular cell astrocytomas show a high frequency of allelic loss but are not a genetically defined subset. Brain Pathology (Zurich, Switzerland). 13: 185-94. PMID 12744472 DOI: 10.1111/J.1750-3639.2003.Tb00018.X  0.389
2003 Brat DJ, Mapstone TB. Malignant glioma physiology: cellular response to hypoxia and its role in tumor progression. Annals of Internal Medicine. 138: 659-68. PMID 12693889 DOI: 10.7326/0003-4819-138-8-200304150-00014  0.364
2003 Kaur B, Brat DJ, Calkins CC, Van Meir EG. Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. The American Journal of Pathology. 162: 19-27. PMID 12507886 DOI: 10.1016/S0002-9440(10)63794-7  0.357
2003 Perry A, Fuller CE, Banerjee R, Brat DJ, Scheithauer BW. Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics. Frontiers in Bioscience : a Journal and Virtual Library. 8: a1-9. PMID 12456321 DOI: 10.2741/896  0.348
2002 Brat DJ, Scheithauer BW, Medina-Flores R, Rosenblum MK, Burger PC. Infiltrative astrocytomas with granular cell features (granular cell astrocytomas): a study of histopathologic features, grading, and outcome. The American Journal of Surgical Pathology. 26: 750-7. PMID 12023579 DOI: 10.1097/00000478-200206000-00008  0.409
2002 Hunter S, Young A, Olson J, Brat DJ, Bowers G, Wilcox JN, Jaye D, Mendrinos S, Neish A. Differential expression between pilocytic and anaplastic astrocytomas: identification of apolipoprotein D as a marker for low-grade, non-infiltrating primary CNS neoplasms. Journal of Neuropathology and Experimental Neurology. 61: 275-81. PMID 11895042 DOI: 10.1093/Jnen/61.3.275  0.367
2002 Brat DJ, Castellano-Sanchez A, Kaur B, Van Meir EG. Genetic and biologic progression in astrocytomas and their relation to angiogenic dysregulation. Advances in Anatomic Pathology. 9: 24-36. PMID 11756757 DOI: 10.1097/00125480-200201000-00004  0.355
2002 Brat DJ. Chordoid glioma further defined Advances in Anatomic Pathology. 9: 77. DOI: 10.1097/00125480-200201000-00016  0.329
2001 Castellano-Sanchez AA, Schemankewitz E, Mazewski C, Brat DJ. Pediatric chordoid glioma with chondroid metaplasia. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 4: 564-7. PMID 11826363 DOI: 10.1007/S10024001-0087-1  0.37
2001 Brat DJ, Scheithauer BW, Eberhart CG, Burger PC. Extraventricular neurocytomas: pathologic features and clinical outcome. The American Journal of Surgical Pathology. 25: 1252-60. PMID 11688459 DOI: 10.1097/00000478-200110000-00005  0.316
2001 Hanes J, Sills A, Zhao Z, Suh KW, Tyler B, DiMeco F, Brat DJ, Choti MA, Leong KW, Pardoll DM, Brem H. Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors. Pharmaceutical Research. 18: 899-906. PMID 11496947 DOI: 10.1023/A:1010963307097  0.316
2001 Evans CO, Young AN, Brown MR, Brat DJ, Parks JS, Neish AS, Oyesiku NM. Novel patterns of gene expression in pituitary adenomas identified by complementary deoxyribonucleic acid microarrays and quantitative reverse transcription-polymerase chain reaction. The Journal of Clinical Endocrinology and Metabolism. 86: 3097-107. PMID 11443173 DOI: 10.1210/Jcem.86.7.7616  0.355
2001 McCarthy DM, Brat DJ, Wilentz RE, Yeo CJ, Cameron JL, Kern SE, Hruban RH. Pancreatic intraepithelial neoplasia and infiltrating adenocarcinoma: analysis of progression and recurrence by DPC4 immunohistochemical labeling. Human Pathology. 32: 638-42. PMID 11431719 DOI: 10.1053/Hupa.2001.24991  0.344
2001 Schultz AB, Brat DJ, Oyesiku NM, Hunter SB. Intrasellar pituicytoma in a patient with other endocrine neoplasms. Archives of Pathology & Laboratory Medicine. 125: 527-30. PMID 11260629 DOI: 10.1043/0003-9985(2001)125<0527:Ipiapw>2.0.Co;2  0.363
2001 Baisden BL, Brat DJ, Melhem ER, Rosenblum MK, King AP, Burger PC. Dysembryoplastic neuroepithelial tumor-like neoplasm of the septum pellucidum: a lesion often misdiagnosed as glioma: report of 10 cases. The American Journal of Surgical Pathology. 25: 494-9. PMID 11257624 DOI: 10.1097/00000478-200104000-00009  0.417
2001 Hirose Y, Aldape K, Bollen A, James CD, Brat D, Lamborn K, Berger M, Feuerstein BG. Chromosomal abnormalities subdivide ependymal tumors into clinically relevant groups American Journal of Pathology. 158: 1137-1143. PMID 11238062 DOI: 10.1016/S0002-9440(10)64061-8  0.354
2000 Houston SC, Crocker IR, Brat DJ, Olson JJ. Extraneural metastatic glioblastoma after interstitial brachytherapy. International Journal of Radiation Oncology, Biology, Physics. 48: 831-6. PMID 11020581 DOI: 10.1016/S0360-3016(00)00662-3  0.369
2000 Ewend MG, Thompson RC, Anderson R, Sills AK, Staveley-O'Carroll K, Tyler BM, Hanes J, Brat D, Thomas M, Jaffee EM, Pardoll DM, Brem H. Intracranial paracrine interleukin-2 therapy stimulates prolonged antitumor immunity that extends outside the central nervous system. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 438-48. PMID 10916753 DOI: 10.1097/00002371-200007000-00007  0.376
2000 Eberhart CG, Brat DJ, Cohen KJ, Burger PC. Pediatric neuroblastic brain tumors containing abundant neuropil and true rosettes. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 3: 346-52. PMID 10890250 DOI: 10.1007/S100249910049  0.416
2000 Lohmann CM, Brat DJ. A conceptual shift in the grading of meningiomas. Advances in Anatomic Pathology. 7: 153-7. PMID 10809221 DOI: 10.1097/00125480-200007030-00004  0.41
2000 Brat DJ, Scheithauer BW, Staugaitis SM, Holtzman RN, Morgello S, Burger PC. Pituicytoma: a distinctive low-grade glioma of the neurohypophysis. The American Journal of Surgical Pathology. 24: 362-8. PMID 10716149 DOI: 10.1097/00000478-200003000-00004  0.407
1999 Brat DJ, Giannini C, Scheithauer BW, Burger PC. Primary melanocytic neoplasms of the central nervous systems. The American Journal of Surgical Pathology. 23: 745-54. PMID 10403296 DOI: 10.1097/00000478-199907000-00001  0.309
1999 Brat DJ, James CD, Jedlicka AE, Connolly DC, Chang E, Castellani RJ, Schmid M, Schiller M, Carson DA, Burger PC. Molecular genetic alterations in radiation-induced astrocytomas. The American Journal of Pathology. 154: 1431-8. PMID 10329596 DOI: 10.1016/S0002-9440(10)65397-7  0.424
1999 Giannini C, Scheithauer BW, Burger PC, Brat DJ, Wollan PC, Lach B, O'Neill BP. Pleomorphic xanthoastrocytoma: what do we really know about it? Cancer. 85: 2033-45. PMID 10223246 DOI: 10.1002/(Sici)1097-0142(19990501)85:9<2033::Aid-Cncr22>3.0.Co;2-Z  0.394
1999 Tihan T, Brat DJ, Goldthwaite PT, Burger PC. GLIONEURONAL TUMORS WITH MALIGNANT HISTOLOGICAL FEATURES Journal of Neuropathology and Experimental Neurology. 58: 509. DOI: 10.1097/00005072-199905000-00013  0.387
1998 Brat DJ, Scheithauer BW, Staugaitis SM, Cortez SC, Brecher K, Burger PC. Third ventricular chordoid glioma: a distinct clinicopathologic entity. Journal of Neuropathology and Experimental Neurology. 57: 283-90. PMID 9600220 DOI: 10.1097/00005072-199803000-00009  0.406
1997 Burger PC, Brat DJ. A Distinctive Pediatric Cns Neuroblastic Tumor: A Clinical And Pathological Description Of Six Cases Journal of Neuropathology and Experimental Neurology. 56: 586. DOI: 10.1097/00005072-199705000-00074  0.382
Low-probability matches (unlikely to be authored by this person)
2016 Halani SH, Holder CA, Griffith B, Nalisnik M, Eschbacher J, Poisson L, Vega JEV, Olson JJ, Cooper L, Brat D. GENT-02. GENETIC ALTERATIONS ASSOCIATED WITH RADIOGRAPHIC FEATURES OF PROGRESSION OF IDH-MUTANT/1p19q CO-DELETED GLIOMAS Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.308  0.299
2018 Mobadersany P, Yousefi S, Amgad M, Gutman DA, Barnholtz-Sloan JS, Velázquez Vega JE, Brat DJ, Cooper LAD. Predicting cancer outcomes from histology and genomics using convolutional networks. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531073 DOI: 10.1073/Pnas.1717139115  0.299
2013 He K, Qi Q, Chan CB, Xiao G, Liu X, Tucker-Burden C, Wang L, Mao H, Lu X, McDonald FE, Luo H, Fan QW, Weiss WA, Sun SY, Brat DJ, et al. Blockade of glioma proliferation through allosteric inhibition of JAK2. Science Signaling. 6: ra55. PMID 23838182 DOI: 10.1126/Scisignal.2003900  0.298
2004 Castellano-Sanchez AA, Li S, Qian J, Lagoo A, Weir E, Brat DJ. Primary central nervous system posttransplant lymphoproliferative disorders. American Journal of Clinical Pathology. 121: 246-53. PMID 14983939 DOI: 10.1309/N82Ctq1J0Xevefqb  0.298
2004 Brat DJ, Seiferheld WF, Perry A, Hammond EH, Murray KJ, Schulsinger AR, Mehta MP, Curran WJ. Analysis of 1p, 19q, 9p, and 10q as prognostic markers for high-grade astrocytomas using fluorescence in situ hybridization on tissue microarrays from Radiation Therapy Oncology Group trials. Neuro-Oncology. 6: 96-103. PMID 15134623 DOI: 10.1215/S1152851703000231  0.297
2013 Marchan EM, Goodman MM, Schuster DM, Vakili J, Olson JJ, Hadjipanayis CG, Brat DJ, Curran WJ, Shu HG, Crocker IR. Impact of FACBC PET in Imaging and GTV Design of Cerebral Gliomas International Journal of Radiation Oncology Biology Physics. 87. DOI: 10.1016/J.Ijrobp.2013.06.650  0.297
2013 Gutman DA, Cobb J, Somanna D, Park Y, Wang F, Kurc T, Saltz JH, Brat DJ, Cooper LA. Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data. Journal of the American Medical Informatics Association : Jamia. 20: 1091-8. PMID 23893318 DOI: 10.1136/Amiajnl-2012-001469  0.297
2020 Pereira AAC, de Jesus Rozante MM, Doveinis RB, Salvarani CP, Anegawa TH, da Costa Souza P, Brat DJ, de Oliveira Borges AC. The recurrence of the melanotic neuroectodermal tumour of infancy: an unusual presentation of a rare tumour. Ecancermedicalscience. 14: 1049. PMID 32565902 DOI: 10.3332/Ecancer.2020.1049  0.296
2021 Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro-Oncology. PMID 34185076 DOI: 10.1093/neuonc/noab106  0.296
2019 Willmarth N, Elder S, Fine A, Ahluwalia MS, Barnholtz-Sloan J, Brastianos PK, Brat D, Mehta MP, Page R, DeVitto R, Robins D. Insight into the brain metastasis journey: Initial survey results from patients and caregivers. Journal of Clinical Oncology. 37: 2069-2069. DOI: 10.1200/Jco.2019.37.15_Suppl.2069  0.296
2008 Olson JJ, McKenzie E, Skurski-Martin M, Zhang Z, Brat D, Phuphanich S. Phase I analysis of BCNU-impregnated biodegradable polymer wafers followed by systemic interferon alfa-2b in adults with recurrent glioblastoma multiforme. Journal of Neuro-Oncology. 90: 293-299. PMID 18679580 DOI: 10.1007/S11060-008-9660-Z  0.295
2001 Brat DJ, Van Meir EG. Glomeruloid microvascular proliferation orchestrated by VPF/VEGF: a new world of angiogenesis research. The American Journal of Pathology. 158: 789-96. PMID 11238026 DOI: 10.1016/S0002-9440(10)64025-4  0.294
2012 Cooper LAD, Yacoub R, Gutman DA, Wang F, Moreno CS, Brat DJ, Bostick RM, Saltz JH. Abstract LB-101: Quantitative imaging of protein expression using multiplex quantum dot immunohistochemistry Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-101  0.293
2021 Kumthekar P, Ko CH, Paunesku T, Dixit K, Sonabend AM, Bloch O, Tate M, Schwartz M, Zuckerman L, Lezon R, Lukas RV, Jovanovic B, McCortney K, Colman H, Chen S, ... ... Brat DJ, et al. A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma. Science Translational Medicine. 13. PMID 33692132 DOI: 10.1126/scitranslmed.abb3945  0.293
2015 Souza C, Malta T, Sabedot T, Stetson L, Tirapelli D, Neder L, Carlotti C, ZenKlusen J, Salama S, Poisson L, Brat D, Barnholtz-Sloan J, Noushmehr H. Epig-16Most Differential Dna Methylation Changes Occur At Candidate Enhancer Elements For Recurrent Lower Grade Glioma And Glioblastoma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov214.16  0.293
2004 Rajaram V, Brat DJ, Perry A. Anaplastic meningioma versus meningeal hemangiopericytoma: immunohistochemical and genetic markers. Human Pathology. 35: 1413-8. PMID 15668900 DOI: 10.1016/J.Humpath.2004.07.017  0.292
1998 Brat DJ, Burger PG. Cerebral Pilocytic Astrocytoma: Distinction from Infiltrating Fibrillary Astrocytomas Pathology Case Reviews. 3: 290-295. DOI: 10.1097/00132583-199811000-00004  0.291
2014 Zhu S, Kisiel W, Lu YJ, Petersen LC, Ndungu JM, Moore TW, Parker ET, Sun A, Liotta DC, El-Rayes BF, Brat DJ, Snyder JP, Shoji M. Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases. Journal of Drug Delivery. 2014: 865732. PMID 25574399 DOI: 10.1155/2014/865732  0.29
2001 Pomper MG, Passe TJ, Burger PC, Scheithauer BW, Brat DJ. Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. Ajnr. American Journal of Neuroradiology. 22: 464-9. PMID 11237967  0.289
1998 Brat DJ, Lillemoe KD, Yeo CJ, Warfield PB, Hruban RH. Progression of pancreatic intraductal neoplasias to infiltrating adenocarcinoma of the pancreas. The American Journal of Surgical Pathology. 22: 163-9. PMID 9500216 DOI: 10.1097/00000478-199802000-00003  0.289
2019 Shimazu Y, Somasundaram A, Brat D, Becher O. Pdtm-13. A Novel Diffuse Midline Glioma Model Initiated In Olig2-Expressing Progenitors Of The Neonatal Brain Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.789  0.289
2018 Verhaak R, Consortium G, Aldape K, Amin S, Ashley D, Barnholtz-Sloan J, Bates A, Beroukhim R, Bock C, Brat D, Claus E, Costello J, de Groot J, Finocchiaro G, French P, et al. DRES-05. MOLECULAR EVOLUTION OF DIFFUSE GLIOMAS AND THE GLIOMA LONGITUDINAL ANALYSIS CONSORTIUM Neuro-Oncology. 20: vi76-vi76. DOI: 10.1093/Neuonc/Noy148.312  0.288
2016 Jakacki RI, Cohen KJ, Buxton A, Krailo MD, Burger PC, Rosenblum MK, Brat DJ, Hamilton RL, Eckel SP, Zhou T, Lavey RS, Pollack IF. Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study. Neuro-Oncology. PMID 27006176 DOI: 10.1093/Neuonc/Now038  0.286
2013 Glass J, Won M, Schultz CJ, Brat D, Bartlett N, Suh JH, Fisher BJ, Liepman MK, Mehta MP. Preirradiation chemotherapy with methotrexate, rituximab, and temozolomide and post-irradiation temozolomide for primary central nervous system lymphoma: RTOG 0227 phase II study results. Journal of Clinical Oncology. 31: 2033-2033. DOI: 10.1200/Jco.2013.31.15_Suppl.2033  0.286
2011 Kashlan ON, Laborde DV, Davison L, Saindane AM, Brat D, Hudgins PA, Gross RE. Meningioangiomatosis: a case report and literature review emphasizing diverse appearance on different imaging modalities. Case Reports in Neurological Medicine. 2011: 361203. PMID 22937336 DOI: 10.1155/2011/361203  0.285
2010 Hammoud DA, Munter FM, Brat DJ, Pomper MG. Magnetic resonance imaging features of pituicytomas: analysis of 10 cases. Journal of Computer Assisted Tomography. 34: 757-61. PMID 20861781 DOI: 10.1097/Rct.0B013E3181E289C0  0.285
2000 Brat DJ, Hirose Y, Cohen KJ, Feuerstein BG, Burger PC. Astroblastoma: clinicopathologic features and chromosomal abnormalities defined by comparative genomic hybridization. Brain Pathology (Zurich, Switzerland). 10: 342-52. PMID 10885653  0.285
2018 Parent EE, Benayoun M, Ibeanu I, Olson JJ, Hadjipanayis CG, Brat DJ, Adhikarla V, Nye J, Schuster DM, Goodman MM. [F]Fluciclovine PET discrimination between high- and low-grade gliomas. Ejnmmi Research. 8: 67. PMID 30046944 DOI: 10.1186/S13550-018-0415-3  0.285
2017 Mukherjee S, Brat DJ. Molecular Programs Underlying Asymmetric Stem Cell Division and Their Disruption in Malignancy. Results and Problems in Cell Differentiation. 61: 401-421. PMID 28409315 DOI: 10.1007/978-3-319-53150-2_18  0.284
2010 Kang SS, Han KS, Ku BM, Lee YK, Hong J, Shin HY, Almonte AG, Woo DH, Brat DJ, Hwang EM, Yoo SH, Chung CK, Park SH, Paek SH, Roh EJ, et al. Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival. Cancer Research. 70: 1173-83. PMID 20103623 DOI: 10.1158/0008-5472.Can-09-2886  0.283
2003 Fan X, Wang Y, Kratz J, Brat DJ, Robitaille Y, Moghrabi A, Perlman EJ, Dang CV, Burger PC, Eberhart CG. hTERT gene amplification and increased mRNA expression in central nervous system embryonal tumors. The American Journal of Pathology. 162: 1763-9. PMID 12759234 DOI: 10.1016/S0002-9440(10)64311-8  0.282
1996 Brat DJ, Hruban RH. Images in clinical medicine. A metastasis caught in the act. The New England Journal of Medicine. 335: 1733. PMID 8929265 DOI: 10.1056/Nejm199612053352304  0.28
2017 Nalisnik M, Amgad M, Lee S, Halani SH, Velazquez Vega JE, Brat DJ, Gutman DA, Cooper LAD. Interactive phenotyping of large-scale histology imaging data with HistomicsML. Scientific Reports. 7: 14588. PMID 29109450 DOI: 10.1038/S41598-017-15092-3  0.28
2014 Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, Aldape K, Brat D, Collins VP, Eberhart C, Figarella-Branger D, Fuller GN, Giangaspero F, Giannini C, Hawkins C, et al. International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathology (Zurich, Switzerland). 24: 429-35. PMID 24990071 DOI: 10.1111/Bpa.12171  0.28
2017 Ross J, Chau M, Miller B, Mukherjee S, Zhang C, Kong J, Kaissi E, Newsam A, Mahboubi D, Berry J, Tucker-Burden C, Brat D. Tmic-14. Hypoxia Inducible Olig2 Mediates Glioma Stem Cell Migration Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.1004  0.279
2020 McCord MR, Bigio EH, Kam KL, Fischer V, Obeidin F, White CL, Brat DJ, Muller WA, Mao Q. Spinocerebellar Ataxia Type 3: A Case Report and Literature Review. Journal of Neuropathology and Experimental Neurology. PMID 32346735 DOI: 10.1093/Jnen/Nlaa033  0.279
2015 Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, ... ... Brat DJ, et al. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nature Cell Biology. PMID 26479318 DOI: 10.1038/Ncb3255  0.276
2020 Goodman AL, Velázquez Vega JE, Rey Martinez LC, Brat DJ, Schniederjan MJ. Epithelioid Pituicytoma: Expanding the Morphologic Spectrum of a Rare Neoplasm. Journal of Neuropathology and Experimental Neurology. PMID 32935128 DOI: 10.1093/Jnen/Nlaa076  0.275
2009 Parsons MJ, Patel P, Brat DJ, Colbert L, Vertino PM. Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells. Cancer Research. 69: 1706-11. PMID 19223547 DOI: 10.1158/0008-5472.Can-08-2351  0.275
2001 Brat DJ, Gearing M, Goldthwaite PT, Wainer BH, Burger PC. Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype. Neuropathology and Applied Neurobiology. 27: 197-205. PMID 11489139 DOI: 10.1046/J.1365-2990.2001.00311.X  0.274
2022 Jamshidi P, Brat DJ. The 2021 WHO classification of central nervous system tumors: what neurologists need to know. Current Opinion in Neurology. 35: 764-771. PMID 36226717 DOI: 10.1097/WCO.0000000000001109  0.274
2000 DiMeco F, Rhines LD, Hanes J, Tyler BM, Brat D, Torchiana E, Guarnieri M, Colombo MP, Pardoll DM, Finocchiaro G, Brem H, Olivi A. Paracrine delivery of IL-12 against intracranial 9L gliosarcoma in rats. Journal of Neurosurgery. 92: 419-27. PMID 10701528 DOI: 10.3171/Jns.2000.92.3.0419  0.273
2017 Yousuf S, Brat DJ, Shu HK, Wang Y, Stein DG, Atif F. Progesterone improves neurocognitive outcomes following therapeutic cranial irradiation in mice. Hormones and Behavior. PMID 28866326 DOI: 10.1016/J.Yhbeh.2017.08.004  0.273
2014 Brat DJ, Ryken TC, Kalkanis SN, Olson JJ. The role of neuropathology in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline. Journal of Neuro-Oncology. 118: 461-78. PMID 24733643 DOI: 10.1007/S11060-013-1331-Z  0.271
1996 Olivi A, Ewend MG, Utsuki T, Tyler B, Domb AJ, Brat DJ, Brem H. Interstitial delivery of carboplatin via biodegradable polymers is effective against experimental glioma in the rat. Cancer Chemotherapy and Pharmacology. 39: 90-6. PMID 8995504 DOI: 10.1007/S002800050542  0.271
2017 Mukherjee S, Tucker-Burden C, Zhang C, Kong J, Chau M, Read R, Brat DJ. Abstract 3897: Novel inhibitor of GBM stem cells targets unique CREB & Myc-mediated self-renewal pathways regulated by CDK5 Cancer Research. 77: 3897-3897. DOI: 10.1158/1538-7445.Am2017-3897  0.271
2020 Hu LS, Brat DJ, Bloch O, Ramkissoon S, Lesser GJ. The Practical Application of Emerging Technologies Influencing the Diagnosis and Care of Patients With Primary Brain Tumors. American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 40: 1-12. PMID 32324425 DOI: 10.1200/EDBK_280955  0.268
2006 Rong Y, Hu F, Huang R, Mackman N, Horowitz JM, Jensen RL, Durden DL, Van Meir EG, Brat DJ. Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Research. 66: 7067-74. PMID 16849552 DOI: 10.1158/0008-5472.Can-06-0346  0.267
2022 Iorgulescu JB, Sun C, Neff C, Cioffi G, Gutierrez C, Kruchko C, Ruhl J, Waite K, Negoita S, Hofferkamp J, Tihan T, McLendon R, Brat DJ, Ostrom QT, Barnholtz-Sloan JS. Molecular Biomarker-Defined Brain Tumors: Epidemiology, Validity, and Completeness in the United States. Neuro-Oncology. PMID 35460555 DOI: 10.1093/neuonc/noac113  0.266
2003 Junge CE, Sugawara T, Mannaioni G, Alagarsamy S, Conn PJ, Brat DJ, Chan PH, Traynelis SF. The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia. Proceedings of the National Academy of Sciences of the United States of America. 100: 13019-24. PMID 14559973 DOI: 10.1073/Pnas.2235594100  0.266
2015 Brat DJ, Cagle PT, Dillon DA, Hattab EM, McLendon RE, Miller MA, Buckner JC. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Tumors of the Central Nervous System. Archives of Pathology & Laboratory Medicine. PMID 25642959 DOI: 10.5858/Arpa.2014-0588-Cp  0.266
2005 Brat DJ, Bellail AC, Van Meir EG. The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro-Oncology. 7: 122-33. PMID 15831231 DOI: 10.1215/S1152851704001061  0.264
2017 Mukherjee S, Tucker-Burden C, Kaissi E, Newsam A, Chau M, Zhang C, Diwedi B, Rupji M, Seby S, Kowalski J, Kong J, Read R, Brat D. STEM-30. CDK5 INHIBITION RESOLVES PKA/cAMP-INDEPENDENT ACTIVATION OF CREB1 SIGNALING IN GLIOMA STEM CELLS Neuro-Oncology. 19: vi232-vi232. DOI: 10.1093/Neuonc/Nox168.945  0.264
2002 Port JD, Brat DJ, Burger PC, Pomper MG. Astroblastoma: radiologic-pathologic correlation and distinction from ependymoma. Ajnr. American Journal of Neuroradiology. 23: 243-7. PMID 11847049  0.262
2019 Mukherjee S, Schiltz G, Clutter M, Mishra R, Olson C, Dunder B, Sharma N, Markwell S, Brat D. Ddis-27. Targeting Atp Docking And P35/P25 Binding Of Cdk5 In Glioma Stem Cells Using Synthetic Inhibitors Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.278  0.261
2018 Chavez JA, Brat DJ, Hunter SB, Velazquez Vega J, Guarner J. Practical Diagnostic Approach to the Presence of Hyphae in Neuropathology Specimens With Three Illustrative Cases. American Journal of Clinical Pathology. PMID 29365030 DOI: 10.1093/Ajcp/Aqx144  0.26
2002 Arbiser JL, Brat D, Hunter S, D'Armiento J, Henske EP, Arbiser ZK, Bai X, Goldberg G, Cohen C, Weiss SW. Tuberous sclerosis-associated lesions of the kidney, brain, and skin are angiogenic neoplasms. Journal of the American Academy of Dermatology. 46: 376-80. PMID 11862172 DOI: 10.1067/Mjd.2002.120530  0.258
2017 Yousefi S, Amrollahi F, Amgad M, Dong C, Lewis JE, Song C, Gutman DA, Halani SH, Vega JEV, Brat DJ, Cooper LAD. Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models. Scientific Reports. 7: 11707. PMID 28916782 DOI: 10.1038/S41598-017-11817-6  0.258
2017 Halani SH, Yousefi S, Baxter-Stoltzfus A, Amgad M, Vega JEV, Olson JJ, Cooper L, Brat DJ. 225 Markers and Mechanisms of Disease Progression in IDH-Mutant Astrocytomas Neurosurgery. 64: 261-262. DOI: 10.1093/Neuros/Nyx417.225  0.257
2011 Wang F, Kong J, Cooper L, Pan T, Kurc T, Chen W, Sharma A, Niedermayr C, Oh TW, Brat D, Farris AB, Foran DJ, Saltz J. A data model and database for high-resolution pathology analytical image informatics. Journal of Pathology Informatics. 2: 32. PMID 21845230 DOI: 10.4103/2153-3539.83192  0.257
2006 Khwaja FW, Nolen JD, Mendrinos SE, Lewis MM, Olson JJ, Pohl J, Van Meir EG, Ritchie JC, Brat DJ. Proteomic analysis of cerebrospinal fluid discriminates malignant and nonmalignant disease of the central nervous system and identifies specific protein markers. Proteomics. 6: 6277-87. PMID 17078017 DOI: 10.1002/Pmic.200600135  0.256
2017 Halani SH, Yousefi S, Vega JEV, Baxter-Stoltzfus A, Olson JJ, Cooper L, Brat D. Path-33. Markers And Mechanisms Of Disease Progression In Idh-Mutant Astrocytomas Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.723  0.255
1999 Pharr V, Litvan I, Brat DJ, Troncoso J, Reich SG, Stark M. Ideomotor apraxia in progressive supranuclear palsy: a case study. Movement Disorders : Official Journal of the Movement Disorder Society. 14: 162-6. PMID 9918365 DOI: 10.1002/1531-8257(199901)14:1<162::Aid-Mds1031>3.0.Co;2-C  0.255
2015 Mukherjee S, Kong J, Brat DJ. Cancer stem cell division: when the rules of asymmetry are broken. Stem Cells and Development. 24: 405-16. PMID 25382732 DOI: 10.1089/Scd.2014.0442  0.255
2020 Brat DJ, Aldape K, Colman H, Figrarella-Branger D, Fuller GN, Giannini C, Holland EC, Jenkins RB, Kleinschmidt-DeMasters B, Komori T, Kros JM, Louis DN, McLean C, Perry A, Reifenberger G, et al. cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas. Acta Neuropathologica. PMID 31996992 DOI: 10.1007/S00401-020-02127-9  0.254
2019 Lu X, Sukhanova M, Gao J, Horbinski C, Jennings L, Mao Q, Bigio E, Brat D, Appin C. 4. Molecular characterizations of adult diffuse gliomas by the Oncoscan CNV Plus assay and next-generation sequencing (NGS) Cancer Genetics and Cytogenetics. DOI: 10.1016/J.Cancergen.2019.04.010  0.254
2013 Appin CL, Brat DJ. Glioblastoma with oligodendroglioma component: A review of clinical, morphologic, and molecular characteristics Pathology Case Reviews. 18: 231-236. DOI: 10.1097/Pcr.0B013E3182A9Ab82  0.254
2018 Shoji M, Qian WP, Nagaraju GP, Brat DJ, Pessolano D, Luzietti R, Chennamadhavuni S, Yamaguchi M, Yang L, Liotta DC. Inhibition of breast cancer metastasis to the lungs with UBS109. Oncotarget. 9: 36102-36109. PMID 30546830 DOI: 10.18632/Oncotarget.26302  0.254
2016 Mukherjee S, Chau M, Tucker-Burden C, Zhang C, Kong J, Read R, Brat D. STMC-24. NOVEL INHIBITOR OF CDK5 SIGNALING AXIS SUPPRESSES SELF-RENEWAL PROPERTIES OF GBM STEM CELLS AND INDUCES APOPTOSIS Neuro-Oncology. 18: vi187-vi187. DOI: 10.1093/Neuonc/Now212.787  0.253
1998 Brat DJ, Jedlicka AE, Connolly DC, Cho KR, Castellani RJ, Burger PC. Radiation-Induced Astrocytomas: Clinicopathologic Features And Molecular Genetic Alterations Journal of Neuropathology and Experimental Neurology. 57: 469. DOI: 10.1097/00005072-199805000-00015  0.253
2002 Brat DJ. Critical Commentary to: Extraventricular Neurocytoma: Morphological and Immunohistochemical Considerations on Differential Diagnosis Pathology Research and Practice. 198: 635-636. DOI: 10.1078/0344-0338-00313  0.252
2020 Penas-Prado M, Wu J, Cahill DP, Brat DJ, Costello JF, Kluetz PG, Cairncross JG, van den Bent M, Verhaak RGW, Aboud O, Burger P, Chang SM, Cordova C, Huang RY, Rowe LS, et al. Proceedings of the Comprehensive Oncology Network Evaluating Rare CNS Tumors (NCI-CONNECT) Oligodendroglioma Workshop. Neuro-Oncology Advances. 2: vdz048. PMID 33289010 DOI: 10.1093/noajnl/vdz048  0.251
2007 Altman DA, Atkinson DS, Brat DJ. Best cases from the AFIP: glioblastoma multiforme. Radiographics : a Review Publication of the Radiological Society of North America, Inc. 27: 883-8. PMID 17495298 DOI: 10.1148/Rg.273065138  0.251
2005 Kerendi F, Halkos ME, Kin H, Corvera JS, Brat DJ, Wagner MB, Vinten-Johansen J, Zhao ZQ, Forbess JM, Kanter KR, Kelley ME, Kirshbom PM. Upregulation of hypoxia inducible factor is associated with attenuation of neuronal injury in neonatal piglets undergoing deep hypothermic circulatory arrest. The Journal of Thoracic and Cardiovascular Surgery. 130: 1079. PMID 16214523 DOI: 10.1016/J.Jtcvs.2005.05.045  0.251
2016 Kaffes I, Szulzewsky F, Alikhanyan K, Herting C, Shelton J, Uhrbom L, Nilsson KF, Nelander S, Westermark B, Huse J, Holland E, Brat D, Hambardzumyan D. TMIC-17. SUBTYPE-SPECIFIC CELLULAR COMPOSITION OF THE GLIOBLASTOMA MICROENVIRONMENT Neuro-Oncology. 18: vi203-vi203. DOI: 10.1093/Neuonc/Now212.857  0.25
2011 Egan KM, Thompson RC, Nabors LB, Olson JJ, Brat DJ, LaRocca RV, Brem S, Moots PL, Madden MH, Browning JE, Chen YA. Erratum to: Cancer susceptibility variants and the risk of adult glioma in a US case–control study Journal of Neuro-Oncology. 104: 543-543. DOI: 10.1007/S11060-011-0527-3  0.249
2014 Tadesse T, Gearing M, Senitzer D, Saxe D, Brat DJ, Bray R, Gebel H, Hill C, Boulis N, Riley J, Feldman E, Johe K, Hazel T, Polak M, Bordeau J, et al. Analysis of graft survival in a trial of stem cell transplant in ALS. Annals of Clinical and Translational Neurology. 1: 900-8. PMID 25540804 DOI: 10.1002/Acn3.134  0.248
2016 Buchwald ZS, Rossi M, Smith G, Abugideiri M, Hauenstein JE, Saxe DF, Neill SG, Ali AN, Brat DJ, Olson JJ, Crocker IR, Shu HK. Genomic Copy Number Complexity Correlates With Overall Survival in Glioblastoma Patients. International Journal of Radiation Oncology, Biology, Physics. 96: S92-S93. PMID 27676052 DOI: 10.1016/J.Ijrobp.2016.06.232  0.248
2019 Mukherjee S, Olson C, Dunder B, Sharma N, Markwell S, Brat D. Stem-19. Resistance Is Futile: Understanding And Targeting The Cdk5-Creb1-Mcl1 Axis To Prevent Radiation Resistance In Glioma Stem Cells Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.992  0.247
2010 Castellino RC, Barwick BG, Schniederjan M, Buss MC, Becher O, Hambardzumyan D, Macdonald TJ, Brat DJ, Durden DL. Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma. Plos One. 5: e10849. PMID 20520772 DOI: 10.1371/Journal.Pone.0010849  0.246
2023 Meredith DM, Cooley LD, Dubuc A, Morrissette J, Sussman RT, Nasrallah MP, Rathbun P, Yap KL, Wadhwani N, Bao L, Wolff DJ, Ida C, Sukhanova M, Horbinski C, Jennings LJ, ... ... Brat D, et al. ROS1 alterations as a potential driver of gliomas in infant, pediatric, and adult patients. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 100294. PMID 37532182 DOI: 10.1016/j.modpat.2023.100294  0.246
2007 Post DE, Sandberg EM, Kyle MM, Devi NS, Brat DJ, Xu Z, Tighiouart M, Meir EGV. Erratum: Targeted cancer gene therapy using a hypoxia inducible factor-dependent oncolytic adenovirus armed with interleukin-4 (Cancer Research (2007) 67, (6872-6881)) Cancer Research. 67: 8422-8423. DOI: 10.1158/0008-5472.Can-67-17-Cor1  0.246
2015 Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, ... ... Brat DJ, et al. Wild-type microglia do not reverse pathology in mouse models of Rett syndrome. Nature. 521: E1-4. PMID 25993969 DOI: 10.1038/Nature14444  0.244
2016 Glass J, Won M, Schultz CJ, Brat D, Bartlett NL, Suh JH, Werner-Wasik M, Fisher BJ, Liepman MK, Augspurger M, Bokstein F, Bovi JA, Solhjem MC, Mehta MP. Phase I and II Study of Induction Chemotherapy With Methotrexate, Rituximab, and Temozolomide, Followed By Whole-Brain Radiotherapy and Postirradiation Temozolomide for Primary CNS Lymphoma: NRG Oncology RTOG 0227. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27022122 DOI: 10.1200/Jco.2015.64.8634  0.242
2013 Wang F, Kong J, Gao J, Cooper LA, Kurc T, Zhou Z, Adler D, Vergara-Niedermayr C, Katigbak B, Brat DJ, Saltz JH. A high-performance spatial database based approach for pathology imaging algorithm evaluation. Journal of Pathology Informatics. 4: 5. PMID 23599905 DOI: 10.4103/2153-3539.108543  0.242
2014 Press RH, Prabhu RS, Appin CL, Brat DJ, Shu HK, Hadjipanayis C, Olson JJ, Oyesiku NM, Curran WJ, Crocker I. Outcomes and patterns of failure for grade 2 meningioma treated with reduced-margin intensity modulated radiation therapy. International Journal of Radiation Oncology, Biology, Physics. 88: 1004-10. PMID 24661652 DOI: 10.1016/J.Ijrobp.2013.12.037  0.242
2015 Zheng S, Lu JJ, Appin C, Brat D, Wang F. Support patient search on pathology reports with interactive online learning based data extraction. Journal of Pathology Informatics. 6: 51. PMID 26605116 DOI: 10.4103/2153-3539.166012  0.241
1999 Brat DJ, Wills ML, Lecksell KL, Epstein JI. How often are diagnostic features missed with less extensive histologic sampling of prostate needle biopsy specimens? The American Journal of Surgical Pathology. 23: 257-62. PMID 10078914 DOI: 10.1097/00000478-199903000-00002  0.24
2011 Moriera F, So K, Gould P, Kamnasaran D, Jensen RL, Hussain I, Gutmann DH, Gorovets D, Kastenhuber ER, Pentsova E, Nayak L, Huse JT, van den Bent MJ, Gravendeel LA, Gorlia T, ... ... Brat DJ, et al. -OMICS AND PROGNOSTIC MARKERS Neuro-Oncology. 13: iii76-iii84. DOI: 10.1093/Neuonc/Nor167  0.24
2016 Selagea L, Mishra A, Anand M, Ross J, Tucker-Burden C, Kong J, Brat DJ. EGFR and C/EBP-β oncogenic signaling is bidirectional in human glioma and varies with the C/EBP-β isoform. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27572958 DOI: 10.1096/Fj.201600550R  0.239
2000 Pieper AA, Blackshaw S, Clements EE, Brat DJ, Krug DK, White AJ, Pinto-Garcia P, Favit A, Conover JR, Snyder SH, Verma A. Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 97: 1845-50. PMID 10677544 DOI: 10.1073/Pnas.97.4.1845  0.239
2005 Pieper AA, Wu X, Han TW, Estill SJ, Dang Q, Wu LC, Reece-Fincanon S, Dudley CA, Richardson JA, Brat DJ, McKnight SL. The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 14052-7. PMID 16172381 DOI: 10.1073/Pnas.0506713102  0.238
2001 O'Reilly FM, Brat DJ, McAlpine BE, Grossniklaus HE, Folpe AL, Arbiser JL. Microphthalmia transcription factor immunohistochemistry: a useful diagnostic marker in the diagnosis and detection of cutaneous melanoma, sentinel lymph node metastases, and extracutaneous melanocytic neoplasms. Journal of the American Academy of Dermatology. 45: 414-9. PMID 11511840 DOI: 10.1067/Mjd.2001.117526  0.238
2007 Tang X, Jang SW, Wang X, Liu Z, Bahr SM, Sun SY, Brat D, Gutmann DH, Ye K. Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation. Nature Cell Biology. 9: 1199-207. PMID 17891137 DOI: 10.1038/Ncb1641  0.238
2021 Alexiev BA, Finkelman BS, Streich L, Bautista MM, Pollack SM, Jennings LJ, Brat DJ. Solitary fibrous tumor of thoracic cavity, extra-thoracic sites and central nervous system: Clinicopathologic features and association with local recurrence and metastasis. Pathology, Research and Practice. 224: 153531. PMID 34171600 DOI: 10.1016/j.prp.2021.153531  0.237
2011 Cooper LA, Kong J, Wang F, Kurc T, Moreno CS, Brat DJ, Saltz JH. MORPHOLOGICAL SIGNATURES AND GENOMIC CORRELATES IN GLIOBLASTOMA. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 1624-1627. PMID 22183148 DOI: 10.1109/ISBI.2011.5872714  0.237
2021 Snyder JM, Huang RY, Bai H, Rao VR, Cornes S, Barnholtz-Sloan JS, Gutman D, Fasano R, Van Meir EG, Brat D, Eschbacher J, Quackenbush J, Wen PY, Lee JW. Analysis of morphological characteristics of IDH-mutant/wildtype brain tumors using whole-lesion phenotype analysis. Neuro-Oncology Advances. 3: vdab088. PMID 34409295 DOI: 10.1093/noajnl/vdab088  0.235
1997 Jinnah HA, Dixon A, Brat DJ, Hellmann DB. Chronic meningitis with cranial neuropathies in Wegener's granulomatosis. Case report and review of the literature. Arthritis and Rheumatism. 40: 573-7. PMID 9082947 DOI: 10.1002/Art.1780400326  0.235
2009 Olson JJ, Fadul CE, Brat DJ, Mukundan S, Ryken TC. Management of newly diagnosed glioblastoma: guidelines development, value and application. Journal of Neuro-Oncology. 93: 1-23. PMID 19430879 DOI: 10.1007/S11060-009-9838-Z  0.234
2001 Pieper AA, Brat DJ, O'Hearn E, Krug DK, Kaplin AI, Takahashi K, Greenberg JH, Ginty D, Molliver ME, Snyder SH. Differential neuronal localizations and dynamics of phosphorylated and unphosphorylated type 1 inositol 1,4,5-trisphosphate receptors. Neuroscience. 102: 433-44. PMID 11166129 DOI: 10.1016/S0306-4522(00)00470-X  0.234
2003 Brat D, Seiferheld W, Perry A, Hammond E, Murray K, Schulsinger A, Mehta M, Curran W. FISH analysis of genetic markers of prognosis for high grade astrocyotmas using tissue micro-arrays from RTOG clinical trials International Journal of Radiation Oncology*Biology*Physics. 57: S135. DOI: 10.1016/S0360-3016(03)00842-3  0.234
2022 Santana-Santos L, Kam KL, Dittmann D, De Vito S, McCord M, Jamshidi P, Fowler H, Wang X, Aalsburg AM, Brat DJ, Horbinski C, Jennings LJ. Validation of Whole Genome Methylation Profiling Classifier for Central Nervous System Tumors. The Journal of Molecular Diagnostics : Jmd. PMID 35605901 DOI: 10.1016/j.jmoldx.2022.04.009  0.233
2007 Gearing M, Brat DJ, Hunter SB, Cooper DS, Tehrani M, Lah JJ. Clinical and neuropathologic findings in a case of posterior cortical atrophy (PCA): 41.8 Journal of Neuropathology and Experimental Neurology. 66: 422. DOI: 10.1097/01.Jnen.0000268991.90394.16  0.233
2007 Gearing M, Brat DJ, Hunter SB, Cooper DS, Tehrani M, Lah JJ. Clinical and neuropathologic findings in a case of posterior cortical atrophy (PCA) The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A22-C  0.233
2022 Waite KA, Cioffi G, Kruchko C, Patil N, Brat DJ, Bruner JM, McLendon RE, Tihan T, Ostrom QT, Barnholtz-Sloan JS. Aligning the Central Brain Tumor Registry of the United States (CBTRUS) histology groupings with current definitions. Neuro-Oncology Practice. 9: 317-327. PMID 35859542 DOI: 10.1093/nop/npac025  0.231
2004 Cushing MM, Brat DJ, Mosunjac MI, Hennigar RA, Jernigan DB, Lanciotti R, Petersen LR, Goldsmith C, Rollin PE, Shieh WJ, Guarner J, Zaki SR. Fatal West Nile virus encephalitis in a renal transplant recipient. American Journal of Clinical Pathology. 121: 26-31. PMID 14750237 DOI: 10.1309/G23Cp54Dar1Bcy8L  0.23
2005 Nowlan A, Nie S, Datta M, Kimbro K, Johnstone P, Brat D. Quantum Dot Nanotechnology for Detection of Gene Product Upregulation in Cultured Glioblastoma Multiforme (GBM) Cells in Response to Hypoxia and Radiation International Journal of Radiation Oncology*Biology*Physics. 63: S476-S477. DOI: 10.1016/J.Ijrobp.2005.07.811  0.229
2013 Press RH, Prabhu RS, Appin CL, Brat DJ, Shu HG, Hadjipanayis C, Olson JJ, Oyesiku NM, Curran WJ, Crocker I. Patterns of Failure for Grade 2/3 Meningioma Treated With Reduced Margin Intensity Modulated Radiation Therapy International Journal of Radiation Oncology Biology Physics. 87. DOI: 10.1016/J.Ijrobp.2013.06.408  0.227
2012 Olson JJ, Voloschin A, Wei L, Miller A, Brat D, Holder C, Shu HK, Hu X, Shim H. 111 Magnetic Resonance Spectroscopic Imaging Measurement of Early Response to Vorinostat Treatment in Recurrent Glioblastoma. Neurosurgery. 71: E546-E547. PMID 28175781 DOI: 10.1227/01.Neu.0000417700.96799.00  0.226
2019 Zhang P, Wang F, Teodoro G, Liang Y, Roy M, Brat D, Kong J. Effective nuclei segmentation with sparse shape prior and dynamic occlusion constraint for glioblastoma pathology images. Journal of Medical Imaging (Bellingham, Wash.). 6: 017502. PMID 30891467 DOI: 10.1117/1.Jmi.6.1.017502  0.224
2002 Bobo W, Stone A, Brat D, Devi S, Meir E, Vertino P. Methylation of the novel apoptotic gene TMS1/ASC in human glioblastoma multiforme International Journal of Radiation Oncology*Biology*Physics. 54: 175. DOI: 10.1016/S0360-3016(02)03360-6  0.223
2003 Brat DJ, Kaur B, Van Meir EG. Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors. Frontiers in Bioscience : a Journal and Virtual Library. 8: d100-16. PMID 12456339  0.223
2022 Tomita Y, Shimazu Y, Somasundaram A, Tanaka Y, Takata N, Ishi Y, Gadd S, Hashizume R, Angione A, Pinero G, Hambardzumyan D, Brat DJ, Hoeman CM, Becher OJ. A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell-of-origin dependent effects of H3K27M. Glia. PMID 35524725 DOI: 10.1002/glia.24189  0.222
2021 Gonzalez-Buendia E, Zhao J, Wang L, Mukherjee S, Zhang D, Arrieta VA, Feldstein E, Kane JR, Kang SJ, Lee-Chang C, Mahajan A, Chen L, Realubit R, Karan C, Magnusson L, ... ... Brat DJ, et al. TOP2B enzymatic activity on promoters and introns modulates multiple oncogenes in human gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34433651 DOI: 10.1158/1078-0432.CCR-21-0312  0.221
1999 Brat DJ, Cohen KJ, Sanders JM, Feuerstein BG, Burger PC. Clinicopathologic Features Of Astroblastoma Journal of Neuropathology and Experimental Neurology. 58: 509. DOI: 10.1097/00005072-199905000-00012  0.221
2013 Adachi K, Sasaki H, Nagahisa S, Yoshida K, Hattori N, Nishiyama Y, Kawase T, Hasegawa M, Abe M, Hirose Y, Alentorn A, Marie Y, Poggioli S, Alshehhi H, Boisselier B, ... ... Brat D, ... ... Brat DJ, et al. OMICS AND PROGNSTIC MARKERS Neuro-Oncology. 15: iii136-iii155. DOI: 10.1093/Neuonc/Not183  0.221
2022 Iorgulescu JB, Sun C, Neff C, Cioffi G, Gutierrez C, Kruchko C, Ruhl J, Waite K, Negoita S, Hofferkamp J, Tihan T, McLendon R, Brat DJ, Ostrom QT, Barnholtz-Sloan JS. Corrigendum to: Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States. Neuro-Oncology. PMID 36534983 DOI: 10.1093/neuonc/noac270  0.22
2018 Mukherjee S, Lee H, Broger L, Olson C, Brat D. STEM-15. CDK5 AND NOTCH SIGNALING CROSSTALK DRIVES SELF-RENEWAL IN GSCs Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.1022  0.219
2015 Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, ... ... Brat DJ, et al. Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome. Nature. PMID 26176914 DOI: 10.1038/Nature14671  0.218
2022 Ostrom QT, Shoaf ML, Cioffi G, Waite K, Kruchko C, Wen PY, Brat D, Barnholtz-Sloan JS, Iorgulescu JB. National-level overall survival patterns for molecularly-defined diffuse glioma types in the United States. Neuro-Oncology. PMID 35994777 DOI: 10.1093/neuonc/noac198  0.218
2010 Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, Capota M, Britt JK, Kotti T, Ure K, Brat DJ, et al. Discovery of a proneurogenic, neuroprotective chemical. Cell. 142: 39-51. PMID 20603013 DOI: 10.1016/J.Cell.2010.06.018  0.216
2023 Wang S, Liu K, Han X, Cheng Y, Zhao E, Brat DJ, Sun Z, Fang D. ATXN3 deubiquitinates YAP1 to promote tumor growth. American Journal of Cancer Research. 13: 4222-4234. PMID 37818078  0.216
2017 Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA. (-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia. Biological Psychiatry. PMID 29246437 DOI: 10.1016/J.Biopsych.2017.10.023  0.216
1999 Pieper AA, Brat DJ, Krug DK, Watkins CC, Gupta A, Blackshaw S, Verma A, Wang ZQ, Snyder SH. Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. Proceedings of the National Academy of Sciences of the United States of America. 96: 3059-64. PMID 10077636 DOI: 10.1073/Pnas.96.6.3059  0.215
2001 Chang AH, Kaufmann WE, Brat DJ. Ectopic cerebellum presenting as a suprasellar mass in infancy: implications for cerebellar development. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 4: 89-93. PMID 11200496 DOI: 10.1007/S100240010128  0.215
2003 Evans CO, Reddy P, Brat DJ, O'Neill EB, Craige B, Stevens VL, Oyesiku NM. Differential expression of folate receptor in pituitary adenomas. Cancer Research. 63: 4218-24. PMID 12874029  0.214
2020 Shlobin NA, Palmer AH, Kam KL, Brat DJ, Potts MB. Bone flap resorption associated with indolent Propionibacterium acnes infection after cranioplasty: case report with pathological analysis. World Neurosurgery. PMID 32217177 DOI: 10.1016/J.Wneu.2020.03.077  0.213
2024 Li J, Shih LK, Brat DJ. Integrated Proteogenomics Uncover Mechanisms of Glioblastoma Evolution, Pointing to Novel Therapeutic Targets. Cancer Research. PMID 38330148 DOI: 10.1158/0008-5472.CAN-24-0452  0.211
1998 Hanes J, Tyler BM, Suh KW, DiMeco F, Brat D, Choti M, Pardoll D, Brem H. Synthetic Cytokine Delivery Systems for Cancer Immunotherapy Neurosurgery. 43: 715-716. DOI: 10.1097/00006123-199809000-00361  0.211
2023 Arrieta VA, Dmello C, McGrail DJ, Brat DJ, Lee-Chang C, Heimberger AB, Chand D, Stupp R, Sonabend AM. Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment. The Journal of Clinical Investigation. 133. PMID 36647828 DOI: 10.1172/JCI163447  0.208
2014 Brat DJ. The modern pathologist: lab data deliverer, interpreter, and diagnostician. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 34: 1-2. PMID 24531315 DOI: 10.1097/Wno.0000000000000097  0.203
2011 Kong J, Cooper LAD, Sharma A, Kurç TM, Brat DJ, Saltz JH. A new steerable pressure force for parametric deformable models Proceedings of Spie. 7962. DOI: 10.1117/12.877700  0.203
2024 Eschbacher KL, Tran QT, Moskalev EA, Jenkins S, Fritchie K, Stoehr R, Caron A, Link MJ, Brown PD, Guajardo A, Brat DJ, Wu A, Santagata S, Louis DN, Brastianos PK, et al. NAB2::STAT6 fusions and genome-wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors. Brain Pathology (Zurich, Switzerland). e13256. PMID 38523251 DOI: 10.1111/bpa.13256  0.201
2021 Kim AE, Wang GM, Waite KA, Elder S, Fine A, Ahluwalia MS, Brat D, Mehta MP, Page R, Dunbar E, Calderone HM, Robins DS, DeVitto R, Willmarth NE, Barnholtz-Sloan JS, et al. Cross-sectional survey of patients, caregivers, and physicians on diagnosis and treatment of brain metastases. Neuro-Oncology Practice. 8: 662-673. PMID 34777835 DOI: 10.1093/nop/npab042  0.199
1996 Ewend MG, Williams JA, Tabassi K, Tyler BM, Babel KM, Anderson RC, Pinn ML, Brat DJ, Brem H. Local delivery of chemotherapy and concurrent external beam radiotherapy prolongs survival in metastatic brain tumor models. Cancer Research. 56: 5217-23. PMID 8912860  0.198
2016 Kallay L, Krummel DP, Methuku KR, Zhang Z, Cook J, Olson J, Brat D, MacDonald T, Sydlik S, Sengupta S. Pdtb-28. Targeting Medulloblastoma With Benzodiazapines Delivered Using Tunable Biodegradable Hydrogels Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.647  0.197
2014 Willie JT, Laxpati NG, Drane DL, Gowda A, Appin C, Hao C, Brat DJ, Helmers SL, Saindane A, Nour SG, Gross RE. Real-time magnetic resonance-guided stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy. Neurosurgery. 74: 569-84; discussion 5. PMID 24618797 DOI: 10.1227/Neu.0000000000000343  0.196
2014 Melson MR, Brat D, Hudgins PJ. An orbital mass in a 5-year-old girl. Journal of Neuro-Ophthalmology. 34: 83-86. PMID 24531319 DOI: 10.1097/Wno.0B013E3182A356C8  0.195
2018 Halani SH, Yousefi S, Vega JV, Rossi MR, Zhao Z, Amrollahi F, Holder CA, Baxter-Stoltzfus A, Eschbacher J, Griffith B, Olson JJ, Jiang T, Yates JR, Eberhart CG, Poisson LM, ... ... Brat DJ, et al. Multi-faceted computational assessment of risk and progression in oligodendroglioma implicates NOTCH and PI3K pathways. Npj Precision Oncology. 2: 24. PMID 30417117 DOI: 10.1038/s41698-018-0067-9  0.194
2010 Vincentelli C, Schniederjan MJ, Brat DJ. 35-year-old HIV-positive woman with Basal forebrain mass. Brain Pathology (Zurich, Switzerland). 20: 265-8. PMID 20438487 DOI: 10.1111/J.1750-3639.2009.00347.X  0.191
2016 Kong J, Zhang P, Liang Y, Teodoro G, Brat DJ, Wang F. Robust Cell Segmentation for Histological Images of Glioblastoma. Proceedings. Ieee International Symposium On Biomedical Imaging. 2016: 1041-1045. PMID 28392891 DOI: 10.1109/ISBI.2016.7493444  0.191
2020 Kam KL, Brooker SM, Mao Q, Barnea Slonim L, Yaseen NR, Brat DJ, Sonabend AM, Lukas RV. Newly diagnosed enhancing lesions: Steroid initiation may impede diagnosis of lymphoma involving the central nervous system. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 81: 61-64. PMID 33222970 DOI: 10.1016/j.jocn.2020.09.014  0.19
2013 Vaphiades MS, Doyle J, Hudgins PA, Brat DJ. Acute monocular visual loss in an elderly woman: a neuro-ophthalmologic emergency. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 33: 390-3. PMID 23792880 DOI: 10.1097/Wno.0B013E318298Facb  0.187
2022 Ramkissoon SH, Fernandes H, Lopez-Terrada DH, Hameed MR, Trembath DG, Bridge JA, Lindeman NI, Souers RJ, Vasalos P, Brat DJ, Moncur JT. Clinical Laboratory Testing Practices in Diffuse Gliomas Prior to Publication of 2021 World Health Organization Classification of Central Nervous System Tumors. Archives of Pathology & Laboratory Medicine. PMID 35878398 DOI: 10.5858/arpa.2021-0431-CP  0.187
2013 Kong J, Wang F, Teodoro G, Cooper L, Moreno CS, Kurc T, Pan T, Saltz J, Brat D. High-Performance Computational Analysis of Glioblastoma Pathology Images with Database Support Identifies Molecular and Survival Correlates. Proceedings. Ieee International Conference On Bioinformatics and Biomedicine. 229-236. PMID 25098236 DOI: 10.1109/BIBM.2013.6732495  0.186
2023 Logun M, Colonna MB, Mueller KP, Ventarapragada D, Rodier R, Tondepu C, Piscopo NJ, Das A, Chvatal S, Hayes HB, Capitini CM, Brat DJ, Kotanchek T, Edison AS, Saha K, et al. Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products. Cytotherapy. PMID 36849306 DOI: 10.1016/j.jcyt.2023.01.008  0.185
2018 Roy M, Wang F, Teodoro G, Vega JV, Brat D, Kong J. Analysis of Cellular Feature Differences of Astrocytomas with Distinct Mutational Profiles Using Digitized Histopathology Images. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2018: 4644-4647. PMID 30441386 DOI: 10.1109/EMBC.2018.8513157  0.181
1997 Gaudin PB, Sherman ME, Brat DJ, Zahurak M, Erozan YS. Accuracy of grading gliomas on CT-guided stereotactic biopsies: a survival analysis. Diagnostic Cytopathology. 17: 461-6. PMID 9407209 DOI: 10.1002/(SICI)1097-0339(199712)17:6<461::AID-DC16>3.0.CO;2-K  0.179
2012 Fujita M, Zhang R, Nakata S, Kuzushima K, Wainwright DA, Balyasnikova IV, Auffinger B, Ahmed AU, Han Y, Lesniak MS, Knight A, Arnouk H, Gillespie GY, Britt W, Su Y, ... ... Brat DJ, et al. LAB-IMMUNOLOGY RESEARCH Neuro-Oncology. 14: vi38-vi42. DOI: 10.1093/Neuonc/Nos223  0.178
2023 Wu SA, Jia DT, Schwartz M, Mulcahy M, Guo K, Tate MC, Sachdev S, Kostelecky N, Escobar DJ, Brat DJ, Heimberger AB, Lukas RV. HER2+ esophageal carcinoma leptomeningeal metastases treated with intrathecal trastuzumab regimen. Cns Oncology. CNS99. PMID 37219390 DOI: 10.2217/cns-2022-0018  0.177
2022 Zhao G, Newbury P, Ishi Y, Chekalin E, Zeng B, Glicksberg BS, Wen A, Paithankar S, Sasaki T, Suri A, Nazarian J, Pacold ME, Brat DJ, Nicolaides T, Chen B, et al. Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma. Acta Neuropathologica Communications. 10: 150. PMID 36274161 DOI: 10.1186/s40478-022-01463-z  0.176
2015 Nazarian SM, Shaon KY, Schwankhaus JD, Chacko JG, Hudgins PA, Brat DJ. Bilateral optic neuropathy after erythematous rash. Bilateral anterior optic neuropathy due to RMSF. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 35: 201-4. PMID 25985435 DOI: 10.1097/Wno.0000000000000261  0.176
2013 Ambady P, Holdhoff M, Ferrigno C, Grossman S, Anderson MD, Liu D, Conrad C, Penas-Prado M, Gilbert MR, Yung AWK, Groot Jd, Aoki T, Nishikawa R, Sugiyama K, Nonoguchi N, ... ... Brat D, et al. Neuro/Medical Oncology Neuro-Oncology. 15: 120-120. DOI: 10.1093/Neuonc/Not182  0.176
2021 Arrieta VA, Chen AX, Kane JR, Kang SJ, Kassab C, Dmello C, Zhao J, Burdett KB, Upadhyayula PS, Lee-Chang C, Shilati J, Jaishankar D, Chen L, Gould A, Zhang D, ... ... Brat DJ, et al. ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma. Nature Cancer. 2: 1372-1386. PMID 35121903 DOI: 10.1038/s43018-021-00260-2  0.167
2004 Govindarajan B, Mizesko MC, Miller MS, Onda H, Nunnelley M, Casper K, Brat D, Cohen C, Arbiser JL, Nunnelly M. Tuberous sclerosis-associated neoplasms express activated p42/44 mitogen-activated protein (MAP) kinase, and inhibition of MAP kinase signaling results in decreased in vivo tumor growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 3469-75. PMID 12960139  0.167
2023 Zhang H, Du Y, Qi L, Xiao S, Braun FK, Kogiso M, Huang Y, Huang F, Abdallah A, Suarez M, Karthick S, Ahmed NM, Salsman VS, Baxter PA, Su JM, ... Brat DJ, et al. Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models. Journal of Translational Medicine. 21: 444. PMID 37415222 DOI: 10.1186/s12967-023-04237-w  0.157
2020 Velázquez Vega JE, Brat DJ, Ryken TC, Olson JJ. The role of neuropathology in the management of newly diagnosed glioblastoma: a systematic review and evidence-based clinical practice guideline. Journal of Neuro-Oncology. 150: 143-164. PMID 33215342 DOI: 10.1007/s11060-020-03616-3  0.154
2022 Shih LK, Mukherjee S, Brat DJ. Off the Clock: the Non-canonical Roles of Cyclin-Dependent Kinases in Neural and Glioma Stem Cell Self-Renewal. Molecular Neurobiology. PMID 36042143 DOI: 10.1007/s12035-022-03009-9  0.153
2022 Halasz LM, Attia A, Bradfield L, Brat DJ, Kirkpatrick JP, Laack NN, Lalani N, Lebow ES, Liu AK, Niemeier HM, Palmer JD, Peters KB, Sheehan J, Thomas RP, Vora SA, et al. Radiation Therapy for IDH-Mutant Grade 2 and Grade 3 Diffuse Glioma: An ASTRO Clinical Practice Guideline. Practical Radiation Oncology. PMID 35902341 DOI: 10.1016/j.prro.2022.05.004  0.149
2022 Shen A, Wang F, Paul S, Bhuvanapalli D, Alayof J, Farris AB, Teodoro G, Brat DJ, Kong J. An integrative web-based software tool for multi-dimensional pathology whole-slide image analytics. Physics in Medicine and Biology. PMID 36067783 DOI: 10.1088/1361-6560/ac8fde  0.147
2011 Kong J, Cooper L, Moreno C, Wang F, Kurc T, Saltz J, Brat D. In silico analysis of nuclei in glioblastoma using large-scale microscopy images improves prediction of treatment response. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 87-90. PMID 22254257 DOI: 10.1109/IEMBS.2011.6089903  0.146
2023 Abdallah AS, Cardona HJ, Gadd SL, Brat DJ, Powla PP, Alruwalli WS, Shen C, Picketts DJ, Li XN, Becher OJ. Novel genetically engineered H3.3G34R model reveals cooperation with ATRX loss in upregulation of cluster genes and promotion of neuronal lineage. Neuro-Oncology Advances. 5: vdad003. PMID 36845293 DOI: 10.1093/noajnl/vdad003  0.142
2017 Zhang P, Wang F, Teodoro G, Liang Y, Brat D, Kong J. AUTOMATED LEVEL SET SEGMENTATION OF HISTOPATHOLOGIC CELLS WITH SPARSE SHAPE PRIOR SUPPORT AND DYNAMIC OCCLUSION CONSTRAINT. Proceedings. Ieee International Symposium On Biomedical Imaging. 2017: 718-722. PMID 28781722 DOI: 10.1109/ISBI.2017.7950620  0.14
2016 Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F, Brat DJ, Rajadhyaksha AM, Pieper AA. The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons. Eneuro. 3. PMID 27066530 DOI: 10.1523/ENEURO.0006-16.2016  0.137
2018 Guo X, Yu H, Rossetti B, Teodoro G, Brat D, Kong J. Clumped Nuclei Segmentation with Adjacent Point Match and Local Shape-Based Intensity Analysis in Fluorescence Microscopy Images. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2018: 3410-3413. PMID 30441120 DOI: 10.1109/EMBC.2018.8512961  0.136
2022 Brat DJ, Aldape K, Bridge JA, Canoll P, Colman H, Hameed MR, Harris BT, Hattab EM, Huse JT, Jenkins RB, Lopez-Terrada DH, McDonald WC, Rodriguez FJ, Souter LH, Colasacco C, et al. Molecular Biomarker Testing for the Diagnosis of Diffuse Gliomas. Archives of Pathology & Laboratory Medicine. PMID 35175291 DOI: 10.5858/arpa.2021-0295-CP  0.134
2015 Kong J, Wang F, Teodoro G, Liang Y, Zhu Y, Tucker-Burden C, Brat DJ. AUTOMATED CELL SEGMENTATION WITH 3D FLUORESCENCE MICROSCOPY IMAGES. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 2015: 1212-1215. PMID 26405506 DOI: 10.1109/ISBI.2015.7164091  0.131
2011 Kong J, Cooper L, Wang F, Chisolm C, Moreno C, Kurc T, Widener P, Brat D, Saltz J. A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 2128-2131. PMID 22249771 DOI: 10.1109/ISBI.2011.5872833  0.13
2012 Cooper LA, Carter AB, Farris AB, Wang F, Kong J, Gutman DA, Widener P, Pan TC, Cholleti SR, Sharma A, Kurc TM, Brat DJ, Saltz JH. Digital Pathology: Data-Intensive Frontier in Medical Imaging: Health-information sharing, specifically of digital pathology, is the subject of this paper which discusses how sharing the rich images in pathology can stretch the capabilities of all otherwise well-practiced disciplines. Proceedings of the Ieee. Institute of Electrical and Electronics Engineers. 100: 991-1003. PMID 25328166 DOI: 10.1109/JPROC.2011.2182074  0.129
2011 Kong J, Cooper L, Kurc T, Brat D, Saltz J. Towards building computerized image analysis framework for nucleus discrimination in microscopy images of diffuse glioma. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 6605-8. PMID 22255853 DOI: 10.1109/IEMBS.2011.6091629  0.115
2017 Rossetti BJ, Wang F, Zhang P, Teodoro G, Brat DJ, Kong J. DYNAMIC REGISTRATION FOR GIGAPIXEL SERIAL WHOLE SLIDE IMAGES. Proceedings. Ieee International Symposium On Biomedical Imaging. 2017: 424-428. PMID 28804569 DOI: 10.1109/ISBI.2017.7950552  0.115
2017 Liang Y, Wang F, Zhang P, Saltz JH, Brat DJ, Kong J. Development of a Framework for Large Scale Three-Dimensional Pathology and Biomarker Imaging and Spatial Analytics. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2017: 75-84. PMID 28815110  0.114
1997 Brat DJ, Hahn SA, Griffin CA, Yeo CJ, Kern SE, Hruban RH. The structural basis of molecular genetic deletions. An integration of classical cytogenetic and molecular analyses in pancreatic adenocarcinoma. The American Journal of Pathology. 150: 383-91. PMID 9033253  0.107
1995 Russell JW, Windebank AJ, McNiven MA, Brat DJ, Brimijoin WS. Effect of cisplatin and ACTH4-9 on neural transport in cisplatin induced neurotoxicity. Brain Research. 676: 258-67. PMID 7613995 DOI: 10.1016/0006-8993(95)00100-5  0.098
2016 Dunn WD, Aerts HJWL, Cooper LA, Holder CA, Hwang SN, Jaffe CC, Brat DJ, Jain R, Flanders AE, Zinn PO, Colen RR, Gutman DA. Assessing the Effects of Software Platforms on Volumetric Segmentation of Glioblastoma. Journal of Neuroimaging in Psychiatry & Neurology. 1: 64-72. PMID 29600296 DOI: 10.17756/jnpn.2016-008  0.097
2022 Arrieta VA, Chen AX, Kane JR, Kang SJ, Kassab C, Dmello C, Zhao J, Burdett KB, Upadhyayula PS, Lee-Chang C, Shilati J, Jaishankar D, Chen L, Gould A, Zhang D, ... ... Brat DJ, et al. Publisher Correction: ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma. Nature Cancer. PMID 35149861 DOI: 10.1038/s43018-022-00343-8  0.081
2021 DeBerge M, Lantz C, Dehn S, Sullivan DP, van der Laan AM, Niessen HWM, Flanagan ME, Brat DJ, Feinstein MJ, Kaushal S, Wilsbacher LD, Thorp EB. Hypoxia-inducible factors individually facilitate inflammatory myeloid metabolism and inefficient cardiac repair. The Journal of Experimental Medicine. 218. PMID 34325467 DOI: 10.1084/jem.20200667  0.081
2012 Brat DJ. Glioblastoma: biology, genetics, and behavior. American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting. 102-7. PMID 24451717 DOI: 10.14694/EdBook_AM.2012.32.102  0.062
2021 McCord M, Lukas RV, Amidei C, Demars N, Gelb A, Buck J, Sachdev S, Feldman A, Tate M, Dixit K, Brat DJ, Jennings L, Horbinski C. Disappearance of MMR-deficient subclones after controlled IL-12 and PD-1 inhibition in a glioma patient. Neuro-Oncology Advances. 3: vdab045. PMID 34250480 DOI: 10.1093/noajnl/vdab045  0.057
1992 Brat DJ, Windebank AJ, Brimijoin S. Emulsifier for intravenous cyclosporin inhibits neurite outgrowth, causes deficits in rapid axonal transport and leads to structural abnormalities in differentiating N1E.115 neuroblastoma. The Journal of Pharmacology and Experimental Therapeutics. 261: 803-10. PMID 1578386  0.05
2019 Voorhees JR, Remy MT, Erickson CM, Dutca LM, Brat DJ, Pieper AA. Occupational-like organophosphate exposure disrupts microglia and accelerates deficits in a rat model of Alzheimer's disease. Npj Aging and Mechanisms of Disease. 5: 3. PMID 30701080 DOI: 10.1038/s41514-018-0033-3  0.045
2003 Castellano-Sanchez AA, Brat DJ. May 2003: 57-year-old-woman with acute loss of strength in her right upper extremity and slurred speech. Brain Pathology (Zurich, Switzerland). 13: 641-2, 645. PMID 14655768  0.04
1993 Brat DJ, Brimijoin S. Acrylamide and glycidamide impair neurite outgrowth in differentiating N1E.115 neuroblastoma without disturbing rapid bidirectional transport of organelles observed by video microscopy. Journal of Neurochemistry. 60: 2145-52. PMID 8492122  0.04
2005 Hamill CE, Goldshmidt A, Nicole O, McKeon RJ, Brat DJ, Traynelis SF. Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery. Clinical Neurosurgery. 52: 29-44. PMID 16626052  0.039
1992 Brat DJ, Brimijoin S. A paradigm for examining toxicant effects on viability, structure, and axonal transport of neurons in culture. Molecular Neurobiology. 6: 125-35. PMID 1282327 DOI: 10.1007/BF02780548  0.022
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