Akrit Sodhi, Ph.D. - Publications

Affiliations: 
2005 University of California, Davis, Davis, CA 
Area:
Oncology, Molecular Biology, Microbiology Biology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang Q, Cai Y, Ma Q, Xiong A, Xu P, Zhang Z, Xu J, Zhou Y, Liu Z, Zhao D, Asara J, Li W, Shi H, Caldwell RB, Sodhi A, et al. Inactivation of adenosine receptor 2A suppresses endothelial-to-mesenchymal transition and inhibits subretinal fibrosis in mice. Science Translational Medicine. 16: eadk3868. PMID 38446902 DOI: 10.1126/scitranslmed.adk3868  0.35
2023 Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, Kedziora KM, Wallace CT, Yu-Wei C, Franks J, Bose D, Rajasundaram D, Hose S, Sahel JA, Puertollano R, ... ... Sodhi A, et al. The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in atrophic AMD. Biorxiv : the Preprint Server For Biology. PMID 37609254 DOI: 10.1101/2023.08.08.552343  0.326
2023 Liu H, Ghosh S, Vaidya T, Bammidi S, Huang C, Shang P, Nair AP, Chowdhury O, Stepicheva NA, Strizhakova A, Hose S, Mitrousis N, Gadde SG, Mb T, Strassburger P, ... ... Sodhi A, et al. Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy. Jci Insight. 8. PMID 37345657 DOI: 10.1172/jci.insight.168945  0.303
2023 Zhang J, Sharma D, Dinabandhu A, Sanchez J, Applewhite B, Jee K, Deshpande M, Flores-Bellver M, Hu MW, Guo C, Salman S, Hwang Y, Anders NM, Rudek MA, Qian J, ... ... Sodhi A, et al. Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice. The Journal of Clinical Investigation. PMID 37227777 DOI: 10.1172/JCI163290  0.317
2022 Liu Z, Shi H, Xu J, Yang Q, Ma Q, Mao X, Xu Z, Zhou Y, Da Q, Cai Y, Fulton DJ, Dong Z, Sodhi A, Caldwell RB, Huo Y. Single-cell transcriptome analyses reveal unique microglia types associated with proliferative retinopathy. Jci Insight. PMID 36264636 DOI: 10.1172/jci.insight.160940  0.343
2022 Liu H, Stepicheva NA, Ghosh S, Shang P, Chowdhury O, Daley RA, Yazdankhah M, Gupta U, Hose SL, Valapala M, Fitting CS, Strizhakova A, Shan Y, Feenstra D, Sahel JA, ... ... Sodhi A, et al. Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy. Nature Communications. 13: 6045. PMID 36229454 DOI: 10.1038/s41467-022-33773-0  0.301
2022 Qin Y, Dinabandhu A, Cao X, Sanchez JC, Jee K, Rodrigues M, Guo C, Zhang J, Vancel J, Menon D, Khan NS, Ma T, Tzeng SY, Daoud YJ, Green JJ, ... ... Sodhi A, et al. ANGPTL4 influences the therapeutic response of neovascular age-related macular degeneration patients by promoting choroidal neovascularization. Jci Insight. PMID 35653189 DOI: 10.1172/jci.insight.157896  0.36
2022 Qin Y, Zhang J, Babapoor-Farrokhran S, Applewhite B, Deshpande M, Megarity H, Flores-Bellver M, Aparicio-Domingo S, Ma T, Rui Y, Tzeng SY, Green JJ, Canto-Soler MV, Montaner S, Sodhi A. PAI-1 is a vascular cell-specific HIF-2-dependent angiogenic factor that promotes retinal neovascularization in diabetic patients. Science Advances. 8: eabm1896. PMID 35235351 DOI: 10.1126/sciadv.abm1896  0.378
2021 Zhang J, Qin Y, Martinez M, Flores-Bellver M, Rodrigues M, Dinabandhu A, Cao X, Deshpande M, Qin Y, Aparicio-Domingo S, Rui Y, Tzeng SY, Salman S, Yuan J, Scott AW, ... ... Sodhi A, et al. HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease. The Journal of Clinical Investigation. 131. PMID 34128478 DOI: 10.1172/JCI139202  0.302
2020 Liu Z, Xu J, Ma Q, Zhang X, Yang Q, Wang L, Cao Y, Xu Z, Tawfik A, Sun Y, Weintraub NL, Fulton DJ, Hong M, Dong Z, Smith LEH, ... ... Sodhi A, et al. Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche. Science Translational Medicine. 12. PMID 32759274 DOI: 10.1126/Scitranslmed.Aay1371  0.437
2019 Sodhi A, Ma T, Menon D, Deshpande M, Jee K, Dinabandhu A, Vancel J, Lu D, Montaner S. Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema. The Journal of Clinical Investigation. PMID 31545295 DOI: 10.1172/Jci120879  0.484
2019 Iftikhar M, Mir TA, Hafiz G, Zimmer-Galler I, Scott AW, Solomon SD, Sodhi A, Wenick AS, Meyerle C, Jiramongkolchai K, Liu TYA, Arevalo JF, Singh M, Kherani S, Handa JT, et al. Loss of Peak Vision in Retinal Vein Occlusion Patients Treated for Macular Edema. American Journal of Ophthalmology. PMID 30954469 DOI: 10.1016/J.Ajo.2019.03.029  0.364
2018 Kherani S, Scott AW, Wenick AS, Zimmer-Galler I, Brady CJ, Sodhi A, Meyerle C, Solomon SD, Shaukat R, Channa R, Adeyemo O, Handa JT, Wang J, Campochiaro PA. Shortest Distance from Fovea to Subfoveal Hemorrhage Border is Important in Patients with Neovascular Age-Related Macular Degeneration. American Journal of Ophthalmology. PMID 29499174 DOI: 10.1016/J.Ajo.2018.02.015  0.368
2017 Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, et al. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 552: 248-252. PMID 29211719 DOI: 10.1038/Nature25013  0.397
2017 Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, Xu X, Yang Q, Zeng X, Zhou Y, Gu X, Lu S, Fu Z, Fulton DJ, Weintraub NL, ... ... Sodhi A, et al. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis. Nature Communications. 8: 584. PMID 28928465 DOI: 10.1038/S41467-017-00551-2  0.52
2017 Applewhite BP, Babapoor-Farrokhran S, Poon D, Hassan SJ, Wellmann E, Ying HS, Semenza GL, Montaner S, Sodhi A. Lack of Evidence for Vasoactive and Inflammatory Mediators in the Promotion of Macular Edema Associated with Epiretinal Membranes. Scientific Reports. 7: 10608. PMID 28878218 DOI: 10.1038/S41598-017-08997-6  0.37
2017 Meng Q, Qin Y, Deshpande M, Kashiwabuchi F, Rodrigues M, Lu Q, Ren H, Elisseeff JH, Semenza GL, Montaner SV, Sodhi A. Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of Pterygia. Investigative Ophthalmology & Visual Science. 58: 4514-4523. PMID 28873177 DOI: 10.1167/Iovs.17-21974  0.475
2017 Jee K, Rodrigues M, Kashiwabuchi F, Applewhite BP, Han I, Lutty G, Goldberg MF, Semenza GL, Montaner S, Sodhi A. Expression of the angiogenic mediator, angiopoietin-like 4, in the eyes of patients with proliferative sickle retinopathy. Plos One. 12: e0183320. PMID 28832635 DOI: 10.1371/Journal.Pone.0183320  0.459
2017 Babapoor-Farrokhran S, Poon D, Solomon S, Montaner S, Sodhi A. Expression of angiogenic mediators in a patient with a retinal artery occlusion. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 52: e122-e125. PMID 28774531 DOI: 10.1016/J.Jcjo.2017.01.010  0.328
2016 Rodrigues M, Kashiwabuchi F, Deshpande M, Jee K, Goldberg MF, Lutty G, Semenza GL, Montaner S, Sodhi A. Expression Pattern of HIF-1α and VEGF Supports Circumferential Application of Scatter Laser for Proliferative Sickle Retinopathy. Investigative Ophthalmology & Visual Science. 57: 6739-6746. PMID 27951596 DOI: 10.1167/Iovs.16-19513  0.422
2016 Paulus YM, Sodhi A. Anti-angiogenic Therapy for Retinal Disease. Handbook of Experimental Pharmacology. PMID 27783271 DOI: 10.1007/164_2016_78  0.456
2016 Campochiaro PA, Hafiz G, Mir TA, Scott AW, Zimmer-Galler I, Shah SM, Wenick AS, Brady CJ, Han I, He L, Channa R, Poon D, Meyerle C, Aronow MB, Sodhi A, et al. Pro-permeability Factors in Diabetic Macular Edema; the Diabetic Macular Edema Treated with Ozurdex Trial. American Journal of Ophthalmology. PMID 27130369 DOI: 10.1016/J.Ajo.2016.04.017  0.348
2016 Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A. Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma. Oncotarget. PMID 26761211 DOI: 10.18632/Oncotarget.6868  0.458
2015 Mir TA, Kherani S, Hafiz G, Scott AW, Zimmer-Galler I, Wenick AS, Solomon S, Han I, Poon D, He L, Shah SM, Brady CJ, Meyerle C, Sodhi A, Linz MO, et al. Changes in Retinal Nonperfusion Associated with Suppression of Vascular Endothelial Growth Factor in Retinal Vein Occlusion. Ophthalmology. PMID 26712560 DOI: 10.1016/J.Ophtha.2015.10.030  0.371
2015 Ma T, Patel H, Babapoor-Farrokhran S, Franklin R, Semenza GL, Sodhi A, Montaner S. KSHV induces aerobic glycolysis and angiogenesis through HIF-1-dependent upregulation of pyruvate kinase 2 in Kaposi's sarcoma. Angiogenesis. PMID 26092770 DOI: 10.1007/S10456-015-9475-4  0.546
2015 Babapoor-Farrokhran S, Jee K, Puchner B, Hassan SJ, Xin X, Rodrigues M, Kashiwabuchi F, Ma T, Hu K, Deshpande M, Daoud Y, Solomon S, Wenick A, Lutty GA, Semenza GL, ... ... Sodhi A, et al. Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy. Proceedings of the National Academy of Sciences of the United States of America. 112: E3030-9. PMID 26039997 DOI: 10.1073/Pnas.1423765112  0.462
2015 Channa R, Sophie R, Bagheri S, Shah SM, Wang J, Adeyemo O, Sodhi A, Wenick A, Ying HS, Campochiaro PA. Regression of choroidal neovascularization results in macular atrophy in anti-vascular endothelial growth factor-treated eyes. American Journal of Ophthalmology. 159: 9-19.e1-2. PMID 25217857 DOI: 10.1016/J.Ajo.2014.09.012  0.412
2014 Asnaghi L, Lin MH, Lim KS, Lim KJ, Tripathy A, Wendeborn M, Merbs SL, Handa JT, Sodhi A, Bar EE, Eberhart CG. Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation. Plos One. 9: e105372. PMID 25166211 DOI: 10.1371/Journal.Pone.0105372  0.402
2014 Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo AA, Rodrigues M, Zaidi MR, Ksander BR, Merlino G, Sodhi A, Chen Q, Gutkind JS. Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry. Cancer Cell. 25: 831-45. PMID 24882515 DOI: 10.1016/J.Ccr.2014.04.016  0.374
2013 Sophie R, Hafiz G, Scott AW, Zimmer-Galler I, Nguyen QD, Ying H, Do DV, Solomon S, Sodhi A, Gehlbach P, Duh E, Baranano D, Campochiaro PA. Long-term outcomes in ranibizumab-treated patients with retinal vein occlusion; the role of progression of retinal nonperfusion. American Journal of Ophthalmology. 156: 693-705. PMID 24053892 DOI: 10.1016/J.Ajo.2013.05.039  0.312
2013 Xin X, Rodrigues M, Umapathi M, Kashiwabuchi F, Ma T, Babapoor-Farrokhran S, Wang S, Hu J, Bhutto I, Welsbie DS, Duh EJ, Handa JT, Eberhart CG, Lutty G, Semenza GL, ... ... Sodhi A, et al. Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4. Proceedings of the National Academy of Sciences of the United States of America. 110: E3425-34. PMID 23959876 DOI: 10.1073/Pnas.1217091110  0.509
2013 Hsu AW, Sodhi A, Eberhart C, Montaner S, Goldberg MF. Regression of choroidal neovascularization in response to systemic chemotherapy for cancer. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 48: e80-2. PMID 23931490 DOI: 10.1016/J.Jcjo.2013.02.004  0.409
2013 Rodrigues M, Iliff NT, Eberhart CG, Montaner S, Sodhi A. Scleral penetration of an unusually aggressive case of a retinal hemangioblastoma. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 48: e67-71. PMID 23931485 DOI: 10.1016/J.Jcjo.2013.01.014  0.359
2013 Rodrigues M, Xin X, Jee K, Babapoor-Farrokhran S, Kashiwabuchi F, Ma T, Bhutto I, Hassan SJ, Daoud Y, Baranano D, Solomon S, Lutty G, Semenza GL, Montaner S, Sodhi A. VEGF secreted by hypoxic Müller cells induces MMP-2 expression and activity in endothelial cells to promote retinal neovascularization in proliferative diabetic retinopathy. Diabetes. 62: 3863-73. PMID 23884892 DOI: 10.2337/Db13-0014  0.437
2011 Jham BC, Ma T, Hu J, Chaisuparat R, Friedman ER, Pandolfi PP, Schneider A, Sodhi A, Montaner S. Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma. Plos One. 6: e19103. PMID 21559457 DOI: 10.1371/Journal.Pone.0019103  0.558
2010 Ma T, Jham BC, Hu J, Friedman ER, Basile JR, Molinolo A, Sodhi A, Montaner S. Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma. Proceedings of the National Academy of Sciences of the United States of America. 107: 14363-8. PMID 20660728 DOI: 10.1073/Pnas.1001065107  0.528
2010 Ma T, Jham BC, Hu J, Friedman ER, Basile JR, Sodhi A, Montaner S. Upregulation of angiopoietin-like 4 by viral G protein-coupled receptor promotes angiogenesis and vascular permeability in Kaposi’s sarcoma Infectious Agents and Cancer. 5. DOI: 10.1186/1750-9378-5-S1-A84  0.487
2006 Sodhi A, Chaisuparat R, Hu J, Ramsdell AK, Manning BD, Sausville EA, Sawai ET, Molinolo A, Gutkind JS, Montaner S. The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Cancer Cell. 10: 133-43. PMID 16904612 DOI: 10.1016/J.Ccr.2006.05.026  0.728
2006 Montaner S, Sodhi A, Ramsdell AK, Martin D, Hu J, Sawai ET, Gutkind JS. The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma. Cancer Research. 66: 168-74. PMID 16397229 DOI: 10.1158/0008-5472.Can-05-1026  0.716
2005 Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck. Cancer Research. 65: 9953-61. PMID 16267020 DOI: 10.1158/0008-5472.Can-05-0921  0.423
2004 Sodhi A, Montaner S, Gutkind JS. Viral hijacking of G-protein-coupled-receptor signalling networks. Nature Reviews. Molecular Cell Biology. 5: 998-1012. PMID 15573137 DOI: 10.1038/Nrm1529  0.369
2004 Montaner S, Sodhi A, Servitja JM, Ramsdell AK, Barac A, Sawai ET, Gutkind JS. The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia. Blood. 104: 2903-11. PMID 15231571 DOI: 10.1182/Blood-2003-12-4436  0.715
2004 Sodhi A, Montaner S, Patel V, Gómez-Román JJ, Li Y, Sausville EA, Sawai ET, Gutkind JS. Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor. Proceedings of the National Academy of Sciences of the United States of America. 101: 4821-6. PMID 15047889 DOI: 10.1073/Pnas.0400835101  0.726
2004 Sodhi A, Montaner S, Gutkind JS. Does dysregulated expression of a deregulated viral GPCR trigger Kaposi's sarcomagenesis? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 422-7. PMID 15003988 DOI: 10.1096/Fj.03-1035Hyp  0.48
2003 Servitja JM, Marinissen MJ, Sodhi A, Bustelo XR, Gutkind JS. Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src. The Journal of Biological Chemistry. 278: 34339-46. PMID 12810717 DOI: 10.1074/Jbc.M302960200  0.387
2003 Montaner S, Sodhi A, Molinolo A, Bugge TH, Sawai ET, He Y, Li Y, Ray PE, Gutkind JS. Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell. 3: 23-36. PMID 12559173 DOI: 10.1016/S1535-6108(02)00237-4  0.713
2002 Sodhi A, Gutkind JS, Montaner S. The Kaposis Sarcoma Associated Herpesvirus: A model for viral oncogenesis Clinical and Translational Oncology. 4: 118-132. DOI: 10.1007/Bf02732341  0.401
2001 Sodhi A, Montaner S, Miyazaki H, Gutkind JS. MAPK and akt Act cooperatively but independently on hypoxia inducible factor-1α in rasV12 upregulation of VEGF Biochemical and Biophysical Research Communications. 287: 292-300. PMID 11549290 DOI: 10.1006/Bbrc.2001.5532  0.406
2001 Montaner S, Sodhi A, Pece S, Mesri EA, Gutkind JS. The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B Cancer Research. 61: 2641-2648. PMID 11289142  0.451
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