Mary I. Townsley - Publications

Affiliations: 
University of South Alabama, Mobile, AL, United States 
Area:
Animal Physiology Biology, Cell Biology, Pathology

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Knighten J, Phillips V, Taylor M, Townsley M, Francis CM. Mitochondria Amplify TRPV4‐dependent Calcium Dynamics within the Pulmonary Microvascular Endothelium The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05650  0.301
2018 Townsley MI. Permeability and calcium signaling in lung endothelium: unpack the box…. Pulmonary Circulation. 8: 2045893217738218. PMID 29040024 DOI: 10.1177/2045893217738218  0.38
2016 Zhou C, Townsley MI, Alexeyev M, Voelkel NF, Stevens T. Endothelial hyperpermeability in severe pulmonary arterial hypertension: Role of store operated calcium entry. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00057.2016. PMID 27422996 DOI: 10.1152/Ajplung.00057.2016  0.451
2016 Yap FC, Weber DS, Taylor MS, Townsley MI, Comer BS, Maylie J, Adelman JP, Lin MT. Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00787.2015. PMID 26945080 DOI: 10.1152/Ajpheart.00787.2015  0.359
2015 Lin MT, Jian MY, Taylor MS, Cioffi DL, Yap FC, Liedtke W, Townsley MI. Functional coupling of TRPV4, IK, and SK channels contributes to Ca(2+)-dependent endothelial injury in rodent lung. Pulmonary Circulation. 5: 279-90. PMID 26064452 DOI: 10.1086/680166  0.396
2015 Bongard RD, Townsley MI, Merker MP. The effects of mitochondrial complex I blockade on ATP and permeability in rat pulmonary microvascular endothelial cells in culture (PMVEC) are overcome by coenzyme Q1 (CoQ1). Free Radical Biology & Medicine. 79: 69-77. PMID 25452141 DOI: 10.1016/J.Freeradbiomed.2014.09.030  0.368
2014 Villalta PC, Rocic P, Townsley MI. Role of MMP2 and MMP9 in TRPV4-induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L652-9. PMID 25150065 DOI: 10.1152/Ajplung.00113.2014  0.376
2013 Villalta PC, Townsley MI. Transient receptor potential channels and regulation of lung endothelial permeability. Pulmonary Circulation. 3: 802-15. PMID 25006396 DOI: 10.1086/674765  0.4
2013 Parker JC, Hashizumi M, Kelly SV, Francis M, Mouner M, Meyer AL, Townsley MI, Wu S, Cioffi DL, Taylor MS. TRPV4 calcium entry and surface expression attenuated by inhibition of myosin light chain kinase in rat pulmonary microvascular endothelial cells. Physiological Reports. 1: e00121. PMID 24303188 DOI: 10.1002/Phy2.121  0.333
2013 Bongard RD, Yan K, Hoffmann RG, Audi SH, Zhang X, Lindemer BJ, Townsley MI, Merker MP. Depleted energy charge and increased pulmonary endothelial permeability induced by mitochondrial complex I inhibition are mitigated by coenzyme Q1 in the isolated perfused rat lung. Free Radical Biology & Medicine. 65: 1455-63. PMID 23912160 DOI: 10.1016/J.Freeradbiomed.2013.07.040  0.424
2012 Townsley MI. Structure and composition of pulmonary arteries, capillaries, and veins. Comprehensive Physiology. 2: 675-709. PMID 23606929 DOI: 10.1002/Cphy.C100081  0.368
2012 Thorneloe KS, Cheung M, Bao W, Alsaid H, Lenhard S, Jian MY, Costell M, Maniscalco-Hauk K, Krawiec JA, Olzinski A, Gordon E, Lozinskaya I, Elefante L, Qin P, Matasic DS, ... ... Townsley MI, et al. An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure. Science Translational Medicine. 4: 159ra148. PMID 23136043 DOI: 10.1126/Scitranslmed.3004276  0.432
2010 Hamanaka K, Jian MY, Townsley MI, King JA, Liedtke W, Weber DS, Eyal FG, Clapp MM, Parker JC. TRPV4 channels augment macrophage activation and ventilator-induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L353-62. PMID 20562229 DOI: 10.1152/Ajplung.00315.2009  0.422
2010 Zhou C, Chen H, King JA, Sellak H, Kuebler WM, Yin J, Townsley MI, Shin HS, Wu S. Alpha1G T-type calcium channel selectively regulates P-selectin surface expression in pulmonary capillary endothelium. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L86-97. PMID 20435690 DOI: 10.1152/Ajplung.00331.2009  0.341
2010 Townsley MI, Morisseau C, Hammock B, King JA. Impact of epoxyeicosatrienoic acids in lung ischemia-reperfusion injury. Microcirculation (New York, N.Y. : 1994). 17: 137-46. PMID 20163540 DOI: 10.1111/J.1549-8719.2009.00013.X  0.34
2009 Wu S, Jian MY, Xu YC, Zhou C, Al-Mehdi AB, Liedtke W, Shin HS, Townsley MI. Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L650-7. PMID 19617313 DOI: 10.1152/Ajplung.00015.2009  0.366
2008 Parker JC, Townsley MI. Physiological determinants of the pulmonary filtration coefficient. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L235-7. PMID 18502816 DOI: 10.1152/Ajplung.00064.2008  0.387
2008 Jian MY, King JA, Al-Mehdi AB, Liedtke W, Townsley MI. High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4. American Journal of Respiratory Cell and Molecular Biology. 38: 386-92. PMID 17962608 DOI: 10.1165/Rcmb.2007-0192Oc  0.463
2007 Hamanaka K, Jian MY, Weber DS, Alvarez DF, Townsley MI, Al-Mehdi AB, King JA, Liedtke W, Parker JC. TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L923-32. PMID 17660328 DOI: 10.1152/Ajplung.00221.2007  0.453
2006 Townsley MI, King JA, Alvarez DF. Ca2+ channels and pulmonary endothelial permeability: insights from study of intact lung and chronic pulmonary hypertension. Microcirculation (New York, N.Y. : 1994). 13: 725-39. PMID 17085430 DOI: 10.1080/10739680600930362  0.389
2006 Townsley MI. Special topics issue of microcirculation: ion channels and pulmonary vascular function. Microcirculation (New York, N.Y. : 1994). 13: 611-3. PMID 17085422 DOI: 10.1080/10739680600930149  0.361
2006 Alvarez DF, King JA, Weber D, Addison E, Liedtke W, Townsley MI. Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury. Circulation Research. 99: 988-95. PMID 17008604 DOI: 10.1161/01.Res.0000247065.11756.19  0.427
2005 Alvarez DF, King JA, Townsley MI. Resistance to store depletion-induced endothelial injury in rat lung after chronic heart failure. American Journal of Respiratory and Critical Care Medicine. 172: 1153-60. PMID 16051904 DOI: 10.1164/Rccm.200506-847Oc  0.422
2005 Wu S, Cioffi EA, Alvarez D, Sayner SL, Chen H, Cioffi DL, King J, Creighton JR, Townsley M, Goodman SR, Stevens T. Essential role of a Ca2+-selective, store-operated current (ISOC) in endothelial cell permeability: determinants of the vascular leak site. Circulation Research. 96: 856-63. PMID 15790951 DOI: 10.1161/01.Res.0000163632.67282.1F  0.354
2004 Parker JC, Townsley MI. Evaluation of lung injury in rats and mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L231-46. PMID 14711798 DOI: 10.1152/Ajplung.00049.2003  0.372
2004 Alvarez DF, Gjerde EA, Townsley MI. Role of EETs in regulation of endothelial permeability in rat lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L445-51. PMID 14578116 DOI: 10.1152/Ajplung.00150.2003  0.401
2003 Dougherty FC, Donovan FM, Townsley MI. Harmonic analysis of perfusion pumps. Journal of Biomechanical Engineering. 125: 814-22. PMID 14986406 DOI: 10.1115/1.1632524  0.368
2003 Trout L, Townsley MI, Bowden AL, Ballard ST. Disruptive effects of anion secretion inhibitors on airway mucus morphology in isolated perfused pig lung. The Journal of Physiology. 549: 845-53. PMID 12702745 DOI: 10.1113/Jphysiol.2002.035923  0.394
2003 Tarpey SB, Sawmiller DR, Kelly C, Thompson WJ, Townsley MI. Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L766-73. PMID 12676767 DOI: 10.1152/Ajplung.00373.2002  0.366
2000 Dyess DL, Collins JN, Ardell JL, Townsley MI, Taylor AE, Ferrara JJ. Modulation of microvascular permeability by 21-aminosteroids after burn injuries Journal of Burn Care & Rehabilitation. 21: 406-413. PMID 11020047 DOI: 10.1097/00004630-200021050-00003  0.318
2000 Zhu D, Bousamra M, Zeldin DC, Falck JR, Townsley M, Harder DR, Roman RJ, Jacobs ER. Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. American Journal of Physiology-Lung Cellular and Molecular Physiology. 278. PMID 10666118 DOI: 10.1152/Ajplung.2000.278.2.L335  0.399
2000 Dyess DL, Hunter JL, Lakey JR, Moyer D, Dougherty FC, Townsley MI. Attenuation of Histamine-Induced Endothelial Permeability Responses after Pacing-Induced Heart Failure: Role for Endogenous Catecholamines Microcirculation. 7: 307-315. DOI: 10.1111/J.1549-8719.2000.Tb00130.X  0.377
1999 Townsley MI, Snell KS, Ivey CL, Culberson DE, Liu DC, Reed RK, Mathieu-Costello O. Remodeling of lung interstitium but not resistance vessels in canine pacing-induced heart failure. Journal of Applied Physiology (Bethesda, Md. : 1985). 87: 1823-30. PMID 10562627 DOI: 10.1152/Jappl.1999.87.5.1823  0.373
1999 Parker JC, Townsley MI, Stevens T. Ca2+ dependence of mechanical injury to lung capillaries. Journal of Applied Physiology (Bethesda, Md. : 1985). 86: 775-6. PMID 10094609 DOI: 10.1152/Jappl.1999.86.2.775  0.413
1998 Ivey CL, Roy BJ, Townsley MI. Ablation of lung endothelial injury after pacing-induced heart failure is related to alterations in Casignaling. American Journal of Physiology. Heart and Circulatory Physiology. 275: H844-H851. PMID 29591929 DOI: 10.1152/Ajpheart.1998.275.3.H844  0.374
1998 Ivey CL, Stephenson AH, Townsley MI. Involvement of cytochrome P-450 enzyme activity in the control of microvascular permeability in canine lung. The American Journal of Physiology. 275: L756-63. PMID 9755108 DOI: 10.1152/Ajplung.1998.275.4.L756  0.348
1998 Taylor AE, Moore TM, Townsley MI. Evaluation of endothelial barrier damage in lungs Pathophysiology. 5: 85-90. DOI: 10.1016/S0928-4680(98)00005-4  0.47
1996 Roy BJ, Pitts VH, Townsley MI. Pulmonary vascular response to angiotensin II in canine pacing-induced heart failure American Journal of Physiology-Heart and Circulatory Physiology. 271. PMID 8760178 DOI: 10.1152/Ajpheart.1996.271.1.H222  0.365
1994 Collins JN, Dyess DL, Ardell JL, Townsley MI, Taylor AE, Ferrara JJ. The effects of albumin administration on microvascular permeability at the site of burn injury. Journal of Trauma-Injury Infection and Critical Care. 36: 27-33. PMID 8295246 DOI: 10.1097/00005373-199401000-00005  0.311
1994 Ferrara JJ, Dyess DL, Collins JN, Fish JM, Markert AJ, Ardell JL, Townsley MI, Flint LM, Taylor AE. Effects of Graded Thermal Injury on Microvascular Permeability at the Site of Injury Journal of Surgical Research. 57: 420-426. PMID 8072291 DOI: 10.1006/Jsre.1994.1164  0.333
1994 Townsley MI, Reed RK, Ishibashi M, Parker JC, Laurent TC, Taylor AE. Hyaluronan efflux from canine lung with increased hydrostatic pressure and saline loading. American Journal of Respiratory and Critical Care Medicine. 150: 1605-11. PMID 7952622 DOI: 10.1164/Ajrccm.150.6.7952622  0.42
1994 Townsley MI, Pitts VH, Ardell JL, Zhao Z, Johnson WH. Altered pulmonary microvascular reactivity to norepinephrine in canine pacing-induced heart failure. Circulation Research. 75: 347-356. PMID 7518365 DOI: 10.1161/01.Res.75.2.347  0.415
1994 Townsley MI, Jordan MA, Pitts VH, Barnes S, Halstead MC. Pulmonary vasoconstriction with serotonin, norepinephrine and histamine following development of canine pacing-induced heart failure of varying duration Pathophysiology. 1: 402. DOI: 10.1016/0928-4680(94)90821-4  0.372
1993 Reed RK, Ishibashi M, Townsley MI, Parker JC, Taylor AE. Blood-to-tissue clearance vs. lymph analysis in determining capillary transport characteristics for albumin in skin. The American Journal of Physiology. 264: H1394-401. PMID 8498553 DOI: 10.1152/Ajpheart.1993.264.5.H1394  0.33
1992 Reed RK, Townsley MI, Pitts VH, Laurent TC, Taylor AE. Increased lymphatic flux of hyaluronan from cat intestine during fat absorption. American Journal of Physiology-Gastrointestinal and Liver Physiology. 263. PMID 1636716 DOI: 10.1152/Ajpgi.1992.263.1.G6  0.317
1992 Townsley MI, Smith SM, Reed RK, Pitts VH, Taylor AE. Ileal microvascular permeability: a comparison of PS and sigma d using lymphatic and isotopic protein clearances American Journal of Physiology-Gastrointestinal and Liver Physiology. 262. PMID 1550244 DOI: 10.1152/Ajpgi.1992.262.3.G572  0.322
1992 Reed RK, Townsley MI, Laurent TC, Taylor AE. Hyaluronan flux from cat intestine: changes with lymph flow. American Journal of Physiology-Heart and Circulatory Physiology. 262. PMID 1539704 DOI: 10.1152/Ajpheart.1992.262.2.H457  0.362
1992 Dyess DL, Ardell JL, Townsley MI, Taylor AE, Ferrara JJ. Effects of hypertonic saline and dextran 70 resuscitation on microvascular permeability after burn. American Journal of Physiology-Heart and Circulatory Physiology. 262. PMID 1377878 DOI: 10.1152/Ajpheart.1992.262.6.H1832  0.348
1991 Townsley MI, Negrini D, Ardell JL. Regional blood flow to canine parietal pleura and internal intercostal muscle. Journal of Applied Physiology. 70: 97-102. PMID 2010416 DOI: 10.1152/Jappl.1991.70.1.97  0.306
1991 Ferrara JJ, Reed RK, Dyess DL, Townsley MI, Onarheim H, Laurent TC, Taylor AE. Increased hyaluronan flux from skin following burn injury Journal of Surgical Research. 50: 240-244. PMID 1999913 DOI: 10.1016/0022-4804(91)90185-O  0.302
1991 Ishibashi M, Reed RK, Townsley MI, Parker JC, Taylor AE. Albumin transport across pulmonary capillary-interstitial barrier in anesthetized dogs. Journal of Applied Physiology (Bethesda, Md. : 1985). 70: 2104-10. PMID 1864792 DOI: 10.1152/Jappl.1991.70.5.2104  0.384
1990 Shibamoto T, Parker JC, Taylor AE, Townsley MI. Derecruitment of filtration surface area in paraquat-injured isolated dog lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 1581-9. PMID 2347796 DOI: 10.1152/Jappl.1990.68.4.1581  0.408
1990 Townsley MI, Barman SA, Taylor AE. Pulmonary embolism: emboli and fibrinolysis inhibition in isolated canine lungs. American Journal of Physiology-Heart and Circulatory Physiology. 258. PMID 2316691 DOI: 10.1152/Ajpheart.1990.258.3.H754  0.417
1990 Townsley MI, Lim EH, Sahawneh TM, Song W. Interaction of chemical and high vascular pressure injury in isolated canine lung Journal of Applied Physiology. 69: 1657-1664. PMID 2272958 DOI: 10.1152/Jappl.1990.69.5.1657  0.443
1988 Townsley MI, Parker JC, Longenecker GL, Perry ML, Pitt RM, Taylor AE. Pulmonary embolism: analysis of endothelial pore sizes in canine lung. The American Journal of Physiology. 255: H1075-83. PMID 3189571 DOI: 10.1152/Ajpheart.1988.255.5.H1075  0.461
1987 Rippe B, Parker JC, Townsley MI, Mortillaro NA, Taylor AE. Segmental vascular resistances and compliances in dog lung Journal of Applied Physiology. 62: 1206-1215. PMID 3571076 DOI: 10.1152/Jappl.1987.62.3.1206  0.371
1987 Townsley MI, Parker JC, Korthuis RJ, Taylor AE. Alterations in hemodynamics and Kf,c during lung mass resection. Journal of Applied Physiology. 63: 2460-2466. PMID 3436877 DOI: 10.1152/Jappl.1987.63.6.2460  0.438
1987 Taylor A, Townsley M. Evaluation of the Starling Fluid Flux Equation Physiology. 2: 48-52. DOI: 10.1152/Physiologyonline.1987.2.2.48  0.312
1986 Townsley MI, Korthuis RJ, Rippe B, Parker JC, Taylor AE. Validation of double vascular occlusion method for Pc,i in lung and skeletal muscle. Journal of Applied Physiology. 61: 127-132. PMID 3733597 DOI: 10.1152/Jappl.1986.61.1.127  0.432
1986 Allison RC, Marble KT, Hernandez EM, Townsley MI, Taylor AE. Attenuation of permeability lung injury after phorbol myristate acetate by verapamil and OKY-046. The American Review of Respiratory Disease. 134: 93-100. PMID 3729167 DOI: 10.1164/Arrd.1986.134.1.93  0.492
1985 Korthuis RJ, Benoit JN, Kvietys PR, Townsley MI, Taylor AE, Granger DN. Humoral factors may mediate increased rat hindquarter blood flow in portal hypertension. The American Journal of Physiology. 249: H827-33. PMID 4051018 DOI: 10.1152/Ajpheart.1985.249.4.H827  0.346
1985 Korthuis RJ, Granger DN, Townsley MI, Taylor AE. The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability. Circulation Research. 57: 599-609. PMID 4042285 DOI: 10.1161/01.Res.57.4.599  0.318
1985 Korthuis RJ, Kerr CR, Townsley MI, Taylor AE. Microvascular pressure, surface area, and permeability in isolated hindquarters of SHR. American Journal of Physiology-Heart and Circulatory Physiology. 249. PMID 4037100 DOI: 10.1152/Ajpheart.1985.249.3.H498  0.312
1985 Townsley MI, Taylor GE, Korthuis RJ, Taylor AE. Promethazine or DPPD pretreatment attenuates oleic acid-induced injury in isolated canine lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 59: 39-46. PMID 4030577 DOI: 10.1152/Jappl.1985.59.1.39  0.4
1985 Korthuis RJ, Granger DN, Townsley MI, Taylor AE. Autoregulation of capillary pressure and filtration rate in isolated rat hindquarters. American Journal of Physiology-Heart and Circulatory Physiology. 248. PMID 4003564 DOI: 10.1152/Ajpheart.1985.248.6.H835  0.307
1985 Rippe B, Townsley M, Parker JC, Taylor AE. Osmotic reflection coefficient for total plasma protein in lung microvessels Journal of Applied Physiology. 58: 436-442. PMID 3980350 DOI: 10.1152/Jappl.1985.58.2.436  0.397
1985 Townsley MI, Korthuis RJ, Taylor AE. Effects of arachidonate on permeability and resistance distribution in canine lungs Journal of Applied Physiology. 58: 206-210. PMID 3917991 DOI: 10.1152/Jappl.1985.58.1.206  0.418
1985 Taylor A, Townsley MI, Korthuis RJ. Macromolecule transport across the pulmonary microvessel walls. Experimental Lung Research. 8: 97-123. PMID 3896771 DOI: 10.3109/01902148509057516  0.448
1985 Townsley MI, Korthuis RJ, Taylor AE. Specific hemodynamic effects of PGE2 and PGF1α in the canine lung Prostaglandins, Leukotrienes and Medicine. 20: 275-282. PMID 3867069 DOI: 10.1016/0262-1746(85)90149-0  0.431
1985 Rippe B, Townsley MI, Taylor AE. Effects of plasma- and cell-free perfusates on filtration coefficient of perfused canine lungs. Journal of Applied Physiology. 58: 1521-1527. PMID 2581928 DOI: 10.1152/Jappl.1985.58.5.1521  0.374
1984 Korthuis RJ, Townsley MI, Rippe B, Taylor AE. Estimation of isogravimetric capillary pressure by a filtration method in skeletal muscle and lung Journal of Applied Physiology. 57: 1817-1823. PMID 6511555 DOI: 10.1152/Jappl.1984.57.6.1817  0.356
1984 Parker JC, Townsley MI, Rippe B, Taylor AE, Thigpen J. Increased microvascular permeability in dog lungs due to high peak airway pressures Journal of Applied Physiology. 57: 1809-1816. PMID 6511554 DOI: 10.1152/Jappl.1984.57.6.1809  0.441
1984 Rippe B, Townsley M, Thigpen J, Parker JC, Korthuis RJ, Taylor AE. Effects of vascular pressure on the pulmonary microvasculature in isolated dog lungs Journal of Applied Physiology. 57: 233-239. PMID 6469784 DOI: 10.1152/Jappl.1984.57.1.233  0.457
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