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Timothy M. Lohman - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
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229 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bonde NJ, Kozlov AG, Cox MM, Lohman TM, Keck JL. Molecular insights into the prototypical single-stranded DNA-binding protein from . Critical Reviews in Biochemistry and Molecular Biology. 1-29. PMID 38770626 DOI: 10.1080/10409238.2024.2330372  0.508
2024 Nguyen B, Hsieh J, Fischer CJ, Lohman TM. Subunit Communication within Dimeric SF1 DNA Helicases. Journal of Molecular Biology. 168578. PMID 38648969 DOI: 10.1016/j.jmb.2024.168578  0.648
2023 Fazio NT, Mersch KN, Hao L, Lohman TM. E. coli RecB Nuclease Domain Regulates RecBCD Helicase Activity but not Single Stranded DNA Translocase Activity. Journal of Molecular Biology. 436: 168381. PMID 38081382 DOI: 10.1016/j.jmb.2023.168381  0.684
2023 Chadda A, Kozlov AG, Nguyen B, Lohman TM, Galburt EA. Mycobacterium tuberculosis Ku stimulates multi-round DNA unwinding by UvrD1 monomers. Journal of Molecular Biology. 168367. PMID 37972687 DOI: 10.1016/j.jmb.2023.168367  0.686
2023 Fazio N, Mersch KN, Hao L, Lohman TM. RecBCD Nuclease Domain Regulates Helicase Activity but not Single Stranded DNA Translocase Activity. Biorxiv : the Preprint Server For Biology. PMID 37905078 DOI: 10.1101/2023.10.13.561901  0.662
2023 Ploetz E, Ambrose B, Barth A, Börner R, Erichson F, Kapanidis AN, Kim HD, Levitus M, Lohman TM, Mazumder A, Rueda D, Steffen FD, Cordes T, Magennis S, Lerner E. A new twist on PIFE: photoisomerisation-related fluorescence enhancement. Methods and Applications in Fluorescence. PMID 37726007 DOI: 10.1088/2050-6120/acfb58  0.51
2023 Mersch KN, Sokoloski JE, Nguyen B, Galletto R, Lohman TM. "Helicase" Activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216777120. PMID 37011199 DOI: 10.1073/pnas.2216777120  0.717
2023 Ploetz E, Ambrose B, Barth A, Börner R, Erichson F, Kapanidis AN, Kim HD, Levitus M, Lohman TM, Mazumder A, Rueda D, Steffen FD, Cordes T, Magennis SW, Lerner E. A new twist on PIFE: photoisomerisation-related fluorescence enhancement. Arxiv. PMID 36866225  0.51
2023 Shinn MK, Chaturvedi SK, Kozlov AG, Lohman TM. Allosteric effects of E. coli SSB and RecR proteins on RecO protein binding to DNA. Nucleic Acids Research. PMID 36808259 DOI: 10.1093/nar/gkad084  0.669
2023 Lohman T. Assessment of Body Composition in Children. Pediatric Exercise Science. 1: 19-30. PMID 36696627 DOI: 10.1123/pes.1.1.19  0.416
2022 Kozlov AG, Cheng X, Zhang H, Shinn MK, Weiland E, Nguyen B, Shkel IA, Zytkiewicz E, Finkelstein IJ, Record MT, Lohman TM. How Glutamate Promotes Liquid-liquid Phase Separation and DNA Binding Cooperativity of E. coli SSB Protein. Journal of Molecular Biology. 434: 167562. PMID 35351518 DOI: 10.1016/j.jmb.2022.167562  0.614
2022 Chadda A, Jensen D, Tomko EJ, Ruiz Manzano A, Nguyen B, Lohman TM, Galburt EA. DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35173050 DOI: 10.1073/pnas.2114501119  0.645
2021 Carney SP, Ma W, Whitley KD, Jia H, Lohman TM, Luthey-Schulten Z, Chemla YR. Kinetic and structural mechanism for DNA unwinding by a non-hexameric helicase. Nature Communications. 12: 7015. PMID 34853304 DOI: 10.1038/s41467-021-27304-6  0.655
2021 Hao L, Zhang R, Lohman TM. Heterogeneity in E. coli RecBCD Helicase-DNA binding and base pair melting. Journal of Molecular Biology. 167147. PMID 34246654 DOI: 10.1016/j.jmb.2021.167147  0.717
2021 Nguyen B, Shinn MK, Weiland E, Lohman TM. Regulation of E. coli Rep helicase activity by PriC. Journal of Molecular Biology. 433: 167072. PMID 34081984 DOI: 10.1016/j.jmb.2021.167072  0.671
2021 Kozlov AG, Lohman TM. Probing E. coli SSB Protein-DNA topology by reversing DNA backbone polarity. Biophysical Journal. PMID 33636169 DOI: 10.1016/j.bpj.2021.02.025  0.664
2021 Shinn MK, Kozlov AG, Lohman TM. Allosteric effects of SSB C-terminal tail on assembly of E. coli RecOR proteins. Nucleic Acids Research. PMID 33450019 DOI: 10.1093/nar/gkaa1291  0.624
2020 Dubiel K, Henry C, Spenkelink LM, Kozlov AG, Wood EA, Jergic S, Dixon NE, van Oijen AM, Cox MM, Lohman TM, Sandler SJ, Keck JL. Development of a single-stranded DNA-binding protein fluorescent fusion toolbox. Nucleic Acids Research. PMID 32374866 DOI: 10.1093/Nar/Gkaa320  0.714
2020 McConnell P, Mekel M, Kozlov AG, Mooren OL, Lohman TM, Cooper JA. Comparative analysis of CPI-motif regulation of biochemical functions of actin capping protein. Biochemistry. PMID 32133840 DOI: 10.1021/Acs.Biochem.0C00092  0.52
2020 McConnell P, Mekel M, Kozlov AG, Mooren OL, Lohman TM, Cooper JA. CPI-motif Regulation of Biochemical Functions of Actin Capping Protein Biophysical Journal. 118: 123a. DOI: 10.1016/J.Bpj.2019.11.807  0.489
2020 Fazio NT, Hao L, Lohman TM. The Nuclease Domain of RecBCD Influences DNA Binding and Helicase Activity Biophysical Journal. 118: 72a. DOI: 10.1016/j.bpj.2019.11.567  0.67
2020 Carney SP, Whitley KD, Ma W, Jia H, Lohman TM, Luthey-Schulten Z, Chemla YR. Direct Measurement of Stepping Dynamics of E. coli UvrD Helicase Biophysical Journal. 118: 71a. DOI: 10.1016/J.Bpj.2019.11.565  0.472
2020 Kozlov AG, Kyung Shinn M, Lohman TM. Regulation of Nearest-Neighbor Cooperative Binding of E. coli SSB Protein to Ssdna by its Intrinsically Disordered Regions Biophysical Journal. 118: 70a. DOI: 10.1016/j.bpj.2019.11.560  0.555
2020 Nguyen B, Weiland E, Lohman TM. Activation of Rep Helicase by PriC Biophysical Journal. 118: 375a. DOI: 10.1016/j.bpj.2019.11.2147  0.469
2020 Hao L, Lohman TM. Allosteric Effects of RecB Nuclease Domain on RecBCD-DNA Interactions Biophysical Journal. 118: 374a. DOI: 10.1016/j.bpj.2019.11.2141  0.624
2020 Shinn MK, Kozlov AG, Lohman TM. Assembly and Binding of E. coli RecOR Proteins to SSB C-Terminal Tails Biophysical Journal. 118: 374a. DOI: 10.1016/j.bpj.2019.11.2137  0.569
2019 Kozlov AG, Shinn MK, Lohman TM. Regulation of Nearest-Neighbor Cooperative Binding of E. coli SSB Protein to DNA. Biophysical Journal. PMID 31708161 DOI: 10.1016/j.bpj.2019.09.047  0.627
2019 Weisz DA, Johnson VM, Niedzwiedzki DM, Shinn MK, Liu H, Klitzke CF, Gross ML, Blankenship RE, Lohman TM, Pakrasi HB. A novel chlorophyll protein complex in the repair cycle of photosystem II. Proceedings of the National Academy of Sciences of the United States of America. PMID 31594847 DOI: 10.1073/Pnas.1909644116  0.512
2019 Ordabayev YA, Nguyen B, Kozlov AG, Jia H, Lohman TM. UvrD helicase activation by MutL involves rotation of its 2B subdomain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31363055 DOI: 10.1073/pnas.1905513116  0.618
2019 Shinn MK, Kozlov AG, Nguyen B, Bujalowski WM, Lohman TM. Are the intrinsically disordered linkers involved in SSB binding to accessory proteins? Nucleic Acids Research. PMID 31329947 DOI: 10.1093/nar/gkz606  0.66
2019 Nguyen B, Ciuba MA, Kozlov AG, Levitus M, Lohman TM. Protein Environment and DNA Orientation Affect Protein-Induced Cy3 Fluorescence Enhancement. Biophysical Journal. PMID 31235181 DOI: 10.1016/J.Bpj.2019.05.026  0.616
2019 Makurath MA, Whitley KD, Nguyen B, Lohman TM, Chemla YR. Regulation of Rep helicase unwinding by an auto-inhibitory subdomain. Nucleic Acids Research. PMID 30690484 DOI: 10.1093/Nar/Gkz023  0.576
2019 Kyung Shinn M, Kozlov AG, Lohman TM. Binding Specificity of E. coli SSB C-Terminal Tails to SIPs Biophysical Journal. 116: 77a. DOI: 10.1016/j.bpj.2018.11.460  0.551
2018 Dubiel K, Myers AR, Kozlov AG, Yang O, Zhang J, Ha T, Lohman TM, Keck JL. Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins. Journal of Molecular Biology. PMID 30472092 DOI: 10.1016/J.Jmb.2018.11.019  0.682
2018 Bea JW, Funk J, Hetherington-Rauth M, Wertheim BC, Mosquiera L, Thuraisingam R, Lee V, Blew R, Lohman T, Roe DJ, Going S. Anthropometry Versus Imaging for Prediction of Inflammation Among Hispanic Girls. Obesity (Silver Spring, Md.). 26: 1594-1602. PMID 30277029 DOI: 10.1002/Oby.22265  0.434
2018 Ordabayev YA, Nguyen B, Niedziela-Majka A, Lohman TM. Regulation of UvrD Helicase Activity by MutL. Journal of Molecular Biology. PMID 30171840 DOI: 10.1016/j.jmb.2018.08.022  0.677
2018 Johnson B, McConnell P, Kozlov AG, Mekel M, Lohman TM, Gross ML, Amarasinghe GK, Cooper JA. Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange. Cell Reports. 23: 2795-2804. PMID 29847807 DOI: 10.1016/J.Celrep.2018.04.096  0.562
2018 Lohman TM, Fazio NT. How Does a Helicase Unwind DNA? Insights from RecBCD Helicase. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 29603305 DOI: 10.1002/bies.201800009  0.675
2018 Antony E, Lohman TM. Dynamics of E. coli single stranded DNA binding (SSB) protein-DNA complexes. Seminars in Cell & Developmental Biology. PMID 29588158 DOI: 10.1016/J.Semcdb.2018.03.017  0.734
2018 Kyung Shinn M, Kozlov AG, Lohman TM. Allosteric Effect of E. coli SSB C-Terminal Tails on RecOR Binding to DNA Biophysical Journal. 114: 441a. DOI: 10.1016/J.BPJ.2017.11.2439  0.66
2017 Nguyen B, Ordabayev Y, Sokoloski JE, Weiland E, Lohman TM. Large domain movements upon UvrD dimerization and helicase activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087333 DOI: 10.1073/pnas.1712882114  0.634
2017 Tomko EJ, Lohman TM. Modulation of Escherichia coli UvrD Single-Stranded DNA Translocation by DNA Base Composition. Biophysical Journal. 113: 1405-1415. PMID 28978435 DOI: 10.1016/J.Bpj.2017.08.023  0.68
2017 Kozlov AG, Shinn MK, Weiland EA, Lohman TM. Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions. Journal of Molecular Biology. PMID 28782560 DOI: 10.1016/j.jmb.2017.07.021  0.64
2017 Sokoloski JE, Galletto R, Lohman TM. Superfamily 1 Helicase PIF1 Can Push Replication Protein a Along Single Stranded DNA and into Duplex DNA Biophysical Journal. 112: 372a. DOI: 10.1016/J.Bpj.2016.11.2020  0.719
2017 Kozlov AG, Kyung Shinn M, Lohman TM. The Role of Intrinsically Disordered Linker and Salt Type on Cooperativity of E. Coli SSB Binding to ssDNA Biophysical Journal. 112: 208a. DOI: 10.1016/j.bpj.2016.11.1150  0.536
2016 Simon MJ, Sokoloski J, Hao L, Weiland E, Lohman TM. Processive DNA Unwinding by RecBCD Helicase in the Absence of Canonical Motor Translocation. Journal of Molecular Biology. PMID 27422010 DOI: 10.1016/J.Jmb.2016.07.002  0.65
2016 Sokoloski JE, Kozlov AG, Galletto R, Lohman TM. Chemo-mechanical pushing of proteins along single-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 27185951 DOI: 10.1073/Pnas.1602878113  0.699
2016 Chowdhury F, Li IT, Ngo TT, Leslie BJ, Kim BC, Sokoloski JE, Weiland E, Wang X, Chemla YR, Lohman TM, Ha T. Defining single molecular forces required for Notch activation using nano yoyo. Nano Letters. PMID 27167603 DOI: 10.1021/Acs.Nanolett.6B01403  0.545
2016 Waldman VM, Weiland E, Kozlov AG, Lohman TM. Is a fully wrapped SSB-DNA complex essential for Escherichia coli survival? Nucleic Acids Research. PMID 27084941 DOI: 10.1093/nar/gkw262  0.645
2016 Whitley KD, Comstock MJ, Jia H, Lohman TM, Chemla YR. Direct Observation of the Stepping Behavior of E. Coli UvrD Helicase Biophysical Journal. 110: 561a. DOI: 10.1016/J.Bpj.2015.11.3000  0.608
2016 Sokoloski JE, Kozlov A, Galletto R, Lohman TM. Single Stranded DNA Translocases can Push Single Stranded DNA Binding Proteins along Single Stranded DNA Biophysical Journal. 110: 240a. DOI: 10.1016/J.Bpj.2015.11.1321  0.69
2015 Suksombat S, Khafizov R, Kozlov AG, Lohman TM, Chemla YR. Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways. Elife. 4. PMID 26305498 DOI: 10.7554/Elife.08193  0.707
2015 Comstock MJ, Whitley KD, Jia H, Sokoloski J, Lohman TM, Ha T, Chemla YR. Protein structure. Direct observation of structure-function relationship in a nucleic acid-processing enzyme. Science (New York, N.Y.). 348: 352-4. PMID 25883359 DOI: 10.1126/Science.Aaa0130  0.572
2015 Petrova V, Chen SH, Molzberger ET, Tomko E, Chitteni-Pattu S, Jia H, Ordabayev Y, Lohman TM, Cox MM. Active displacement of RecA filaments by UvrD translocase activity. Nucleic Acids Research. 43: 4133-49. PMID 25824953 DOI: 10.1093/Nar/Gkv186  0.7
2015 Harris M, Farrell V, Houtkooper L, Going S, Lohman T. Associations of polyunsaturated Fatty Acid intake with bone mineral density in postmenopausal women. Journal of Osteoporosis. 2015: 737521. PMID 25785226 DOI: 10.1155/2015/737521  0.413
2015 Kozlov AG, Weiland E, Mittal A, Waldman V, Antony E, Fazio N, Pappu RV, Lohman TM. Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA. Journal of Molecular Biology. 427: 763-74. PMID 25562210 DOI: 10.1016/J.Jmb.2014.12.020  0.675
2015 Suksombat S, Khafizov R, Kozlov AG, Lohman TM, Chemla YR. Author response: Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways Elife. DOI: 10.7554/Elife.08193.024  0.5
2014 Nguyen B, Sokoloski J, Galletto R, Elson EL, Wold MS, Lohman TM. Diffusion of human replication protein A along single-stranded DNA. Journal of Molecular Biology. 426: 3246-61. PMID 25058683 DOI: 10.1016/J.Jmb.2014.07.014  0.651
2014 Lee KS, Marciel AB, Kozlov AG, Schroeder CM, Lohman TM, Ha T. Ultrafast redistribution of E. coli SSB along long single-stranded DNA via intersegment transfer. Journal of Molecular Biology. 426: 2413-21. PMID 24792418 DOI: 10.1016/J.Jmb.2014.04.023  0.669
2014 Nguyen B, Sokoloski J, Wold MS, Galletto R, Elson EL, Lohman TM. Human Replication Protein a (RPA) Can Diffuse Along Single Stranded DNA Biophysical Journal. 106: 73a. DOI: 10.1016/J.Bpj.2013.11.480  0.69
2014 Suksombat S, Kozlov AG, Lohman TM, Chemla YR. Partial Unwrapping of SSB from SsDNA Facilitates RecA Filament Formation Biophysical Journal. 106: 698a-699a. DOI: 10.1016/J.Bpj.2013.11.3864  0.702
2013 Antony E, Weiland E, Yuan Q, Manhart CM, Nguyen B, Kozlov AG, McHenry CS, Lohman TM. Multiple C-terminal tails within a single E. coli SSB homotetramer coordinate DNA replication and repair. Journal of Molecular Biology. 425: 4802-19. PMID 24021816 DOI: 10.1016/J.Jmb.2013.08.021  0.697
2013 Qiu Y, Antony E, Doganay S, Koh HR, Lohman TM, Myong S. Srs2 prevents Rad51 filament formation by repetitive motion on DNA. Nature Communications. 4: 2281. PMID 23939144 DOI: 10.1038/Ncomms3281  0.665
2013 Lee KS, Balci H, Jia H, Lohman TM, Ha T. Direct imaging of single UvrD helicase dynamics on long single-stranded DNA. Nature Communications. 4: 1878. PMID 23695672 DOI: 10.1038/Ncomms2882  0.699
2013 Xie F, Wu CG, Weiland E, Lohman TM. Asymmetric regulation of bipolar single-stranded DNA translocation by the two motors within Escherichia coli RecBCD helicase. The Journal of Biological Chemistry. 288: 1055-64. PMID 23192341 DOI: 10.1074/Jbc.M112.423384  0.664
2013 Qiu Y, Anthony E, Lohman T, Myong S. Srs2 Prevents Rad51 Filament Formation by Repetitive Scrunching of DNA Biophysical Journal. 104: 75a. DOI: 10.1016/J.Bpj.2012.11.452  0.673
2013 Comstock MJ, Jia H, Lohman TM, Ha T, Chemla YR. Simultaneous High-Resolution Optical Trapping and Single Molecule Fluorescence Measurements of the UvrD Helicase: DNA Motor Protein Structure and Function Observed Simultaneously Biophysical Journal. 104: 516a. DOI: 10.1016/J.Bpj.2012.11.2854  0.644
2012 Kozlov AG, Galletto R, Lohman TM. SSB-DNA binding monitored by fluorescence intensity and anisotropy. Methods in Molecular Biology (Clifton, N.J.). 922: 55-83. PMID 22976177 DOI: 10.1007/978-1-62703-032-8_4  0.661
2012 Kozlov AG, Lohman TM. SSB binding to ssDNA using isothermal titration calorimetry. Methods in Molecular Biology (Clifton, N.J.). 922: 37-54. PMID 22976176 DOI: 10.1007/978-1-62703-032-8_3  0.654
2012 Wu CG, Xie F, Lohman TM. The primary and secondary translocase activities within E. coli RecBC helicase are tightly coupled to ATP hydrolysis by the RecB motor. Journal of Molecular Biology. 423: 303-14. PMID 22820092 DOI: 10.1016/J.Jmb.2012.07.009  0.645
2012 Fischer CJ, Tomko EJ, Wu CG, Lohman TM. Fluorescence methods to study DNA translocation and unwinding kinetics by nucleic acid motors. Methods in Molecular Biology (Clifton, N.J.). 875: 85-104. PMID 22573437 DOI: 10.1007/978-1-61779-806-1_5  0.599
2012 Antony E, Kozlov AG, Nguyen B, Lohman TM. Plasmodium falciparum SSB tetramer binds single-stranded DNA only in a fully wrapped mode. Journal of Molecular Biology. 420: 284-95. PMID 22543238 DOI: 10.1016/J.Jmb.2012.04.022  0.711
2012 Antony E, Weiland EA, Korolev S, Lohman TM. Plasmodium falciparum SSB tetramer wraps single-stranded DNA with similar topology but opposite polarity to E. coli SSB. Journal of Molecular Biology. 420: 269-83. PMID 22543099 DOI: 10.1016/J.Jmb.2012.04.021  0.705
2012 Ha T, Kozlov AG, Lohman TM. Single-molecule views of protein movement on single-stranded DNA. Annual Review of Biophysics. 41: 295-319. PMID 22404684 DOI: 10.1146/Annurev-Biophys-042910-155351  0.652
2012 Tomko EJ, Fischer CJ, Lohman TM. Single-stranded DNA translocation of E. coli UvrD monomer is tightly coupled to ATP hydrolysis. Journal of Molecular Biology. 418: 32-46. PMID 22342931 DOI: 10.1016/J.Jmb.2012.02.013  0.617
2012 Jia H, Korolev S, Niedziela-Majka A, Maluf NK, Gauss GH, Myong S, Ha T, Waksman G, Lohman TM. Corrigendum to “Rotations of the 2B Sub-Domain of E. coli UvrD Helicase/Translocase Coupled to Nucleotide and DNA Binding” [J. Mol. Biol. 411/3 (2011) 633–648] Journal of Molecular Biology. 418: 264-265. DOI: 10.1016/J.Jmb.2012.02.030  0.59
2011 Balci H, Arslan S, Myong S, Lohman TM, Ha T. Single-molecule nanopositioning: structural transitions of a helicase-DNA complex during ATP hydrolysis. Biophysical Journal. 101: 976-84. PMID 21843490 DOI: 10.1016/J.Bpj.2011.07.010  0.62
2011 Niedziela-Majka A, Maluf NK, Antony E, Lohman TM. Self-assembly of Escherichia coli MutL and its complexes with DNA. Biochemistry. 50: 7868-80. PMID 21793594 DOI: 10.1021/Bi200753B  0.636
2011 Zhou R, Kozlov AG, Roy R, Zhang J, Korolev S, Lohman TM, Ha T. SSB functions as a sliding platform that migrates on DNA via reptation. Cell. 146: 222-32. PMID 21784244 DOI: 10.1016/J.Cell.2011.06.036  0.693
2011 Jia H, Korolev S, Niedziela-Majka A, Maluf NK, Gauss GH, Myong S, Ha T, Waksman G, Lohman TM. Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding. Journal of Molecular Biology. 411: 633-48. PMID 21704638 DOI: 10.1016/J.Jmb.2011.06.019  0.671
2011 Kozlov AG, Lohman TM. E. coli SSB tetramer binds the first and second molecules of (dT)(35) with heat capacities of opposite sign. Biophysical Chemistry. 159: 48-57. PMID 21636209 DOI: 10.1016/j.bpc.2011.05.005  0.58
2011 Zhou R, Kozlov AG, Roy R, Zhang J, Korolev S, Lohman TM, Ha T. Erratum: SSB functions as a sliding platform that migrates on DNA via reptation (Cell (2011) 146 (222-232)) Cell. 146. DOI: 10.1016/J.Cell.2011.07.027  0.349
2010 Tomko EJ, Jia H, Park J, Maluf NK, Ha T, Lohman TM. 5'-Single-stranded/duplex DNA junctions are loading sites for E. coli UvrD translocase. The Embo Journal. 29: 3826-39. PMID 20877334 DOI: 10.1038/Emboj.2010.242  0.682
2010 Wu CG, Bradford C, Lohman TM. Escherichia coli RecBC helicase has two translocase activities controlled by a single ATPase motor. Nature Structural & Molecular Biology. 17: 1210-7. PMID 20852646 DOI: 10.1038/Nsmb.1901  0.667
2010 Kozlov AG, Eggington JM, Cox MM, Lohman TM. Binding of the dimeric Deinococcus radiodurans single-stranded DNA binding protein to single-stranded DNA. Biochemistry. 49: 8266-75. PMID 20795631 DOI: 10.1021/Bi100920W  0.7
2010 Park J, Myong S, Niedziela-Majka A, Lee KS, Yu J, Lohman TM, Ha T. PcrA helicase dismantles RecA filaments by reeling in DNA in uniform steps. Cell. 142: 544-55. PMID 20723756 DOI: 10.1016/J.Cell.2010.07.016  0.695
2010 Lohman TM. Clipping along. Journal of Molecular Biology. 399: 663-4. PMID 20447403 DOI: 10.1016/j.jmb.2010.04.063  0.399
2010 Tomko EJ, Fischer CJ, Lohman TM. Ensemble methods for monitoring enzyme translocation along single stranded nucleic acids. Methods (San Diego, Calif.). 51: 269-76. PMID 20371288 DOI: 10.1016/J.Ymeth.2010.03.010  0.505
2010 Kozlov AG, Cox MM, Lohman TM. Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein. The Journal of Biological Chemistry. 285: 17246-52. PMID 20360609 DOI: 10.1074/Jbc.M110.118273  0.693
2010 Kozlov AG, Jezewska MJ, Bujalowski W, Lohman TM. Binding specificity of Escherichia coli single-stranded DNA binding protein for the chi subunit of DNA pol III holoenzyme and PriA helicase. Biochemistry. 49: 3555-66. PMID 20329707 DOI: 10.1021/Bi100069S  0.702
2010 Fischer CJ, Wooten L, Tomko EJ, Lohman TM. Kinetics of motor protein translocation on single-stranded DNA. Methods in Molecular Biology (Clifton, N.J.). 587: 45-56. PMID 20225141 DOI: 10.1007/978-1-60327-355-8_4  0.628
2010 Lohman TM. Kinetics of the t4 gene 32 protein-single-stranded nucleic Acid interaction. Biophysical Journal. 32: 458-60. PMID 19431394 DOI: 10.1016/S0006-3495(80)84982-4  0.536
2010 Kozlov AG, Bujalowski W, Lohman TM. Specificity of E.coli SSB Protein Binding To the Chi Subunit of DNA Pol III He and Pria Helicase in the Presence and Absence of ssDNA Biophysical Journal. 98: 65a. DOI: 10.1016/J.Bpj.2009.12.370  0.696
2010 Khafizov RG, Kozlov AG, Lohman TM, Chemla Y. E.coli SSB Under Tension Biophysical Journal. 98: 270a. DOI: 10.1016/J.Bpj.2009.12.1470  0.681
2010 Zhou R, Roy R, Kozlov AG, Lohman TM, Ha T. Probing Protein Diffusion and Dissociation Mechanisms on DNA Using Fluorescence-Force Spectroscopy Biophysical Journal. 98: 269a. DOI: 10.1016/J.Bpj.2009.12.1464  0.67
2010 Wu CG, Lohman TM. E. Coli RecBC Helicase Actively Translocates on Both Strands during DNA Unwinding Biophysical Journal. 98: 268a. DOI: 10.1016/J.Bpj.2009.12.1463  0.663
2010 Tomko EJ, Maluf NK, Lohman TM. 5′-Single Stranded DNA Duplex Junctions Provide Specific Loading Sites for the E. coli UvrD Single Stranded DNA Translocase Biophysical Journal. 98: 267a. DOI: 10.1016/J.Bpj.2009.12.1456  0.705
2010 Jia H, Niedziela-Majka A, Korolev S, Ha T, Lohman T. Fret Studies of the Conformational Changes in the 2b Sub-Domain of UvrD Helicase Biophysical Journal. 98: 23a. DOI: 10.1016/J.Bpj.2009.12.136  0.645
2010 Park J, Myong S, Niedziela-Majka A, Yu J, Lohman T, Ha T. Reeling in DNA One Base at A Time: pcrA Translocation Coupled to DNA Looping Dismantles RecA Filaments Biophysical Journal. 98: 221a. DOI: 10.1016/J.Bpj.2009.12.1190  0.699
2009 Roy R, Kozlov AG, Lohman TM, Ha T. SSB protein diffusion on single-stranded DNA stimulates RecA filament formation. Nature. 461: 1092-7. PMID 19820696 DOI: 10.1038/Nature08442  0.718
2009 Antony E, Tomko EJ, Xiao Q, Krejci L, Lohman TM, Ellenberger T. Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA. Molecular Cell. 35: 105-15. PMID 19595720 DOI: 10.1016/J.Molcel.2009.05.026  0.687
2009 Roy R, Kozlov AG, Lohman TM, Ha T. Erratum: SSB protein diffusion on single-stranded DNA stimulates RecA filament formation Nature. 462: 944-944. DOI: 10.1038/Nature08600  0.628
2008 Pratt C, Webber LS, Baggett CD, Ward D, Pate RR, Murray D, Lohman T, Lytle L, Elder JP. Sedentary activity and body composition of middle school girls: the trial of activity for adolescent girls. Research Quarterly For Exercise and Sport. 79: 458-67. PMID 19177947 DOI: 10.1080/02701367.2008.10599512  0.433
2008 Shereda RD, Kozlov AG, Lohman TM, Cox MM, Keck JL. SSB as an organizer/mobilizer of genome maintenance complexes. Critical Reviews in Biochemistry and Molecular Biology. 43: 289-318. PMID 18937104 DOI: 10.1080/10409230802341296  0.677
2008 Wu CG, Lohman TM. Influence of DNA end structure on the mechanism of initiation of DNA unwinding by the Escherichia coli RecBCD and RecBC helicases. Journal of Molecular Biology. 382: 312-26. PMID 18656489 DOI: 10.1016/J.Jmb.2008.07.012  0.689
2008 Lohman TM, Tomko EJ, Wu CG. Non-hexameric DNA helicases and translocases: mechanisms and regulation. Nature Reviews. Molecular Cell Biology. 9: 391-401. PMID 18414490 DOI: 10.1038/Nrm2394  0.688
2008 Wong CJ, Lohman TM. Kinetic control of Mg2+-dependent melting of duplex DNA ends by Escherichia coli RecBC. Journal of Molecular Biology. 378: 761-77. PMID 18395743 DOI: 10.1016/j.jmb.2008.03.023  0.705
2008 Farr JN, Going SB, Lohman T, Cussler E, Kasle S, Cornett M, Nelson E, Wright J. Effects of an Education and Exercise Intervention on Physical Activity in Early Knee Osteoarthritis Patients Medicine & Science in Sports & Exercise. 40: S252. DOI: 10.1249/01.Mss.0000322573.21562.31  0.408
2007 Chen Z, Wang Z, Lohman T, Heymsfield SB, Outwater E, Nicholas JS, Bassford T, LaCroix A, Sherrill D, Punyanitya M, Wu G, Going S. Dual-energy X-ray absorptiometry is a valid tool for assessing skeletal muscle mass in older women. The Journal of Nutrition. 137: 2775-80. PMID 18029498 DOI: 10.1093/Jn/137.12.2775  0.418
2007 Niedziela-Majka A, Chesnik MA, Tomko EJ, Lohman TM. Bacillus stearothermophilus PcrA monomer is a single-stranded DNA translocase but not a processive helicase in vitro. The Journal of Biological Chemistry. 282: 27076-85. PMID 17631491 DOI: 10.1074/Jbc.M704399200  0.581
2007 Tomko EJ, Fischer CJ, Niedziela-Majka A, Lohman TM. A nonuniform stepping mechanism for E. coli UvrD monomer translocation along single-stranded DNA. Molecular Cell. 26: 335-47. PMID 17499041 DOI: 10.1016/J.Molcel.2007.03.024  0.64
2007 Roy R, Kozlov AG, Lohman TM, Ha T. Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein. Journal of Molecular Biology. 369: 1244-57. PMID 17490681 DOI: 10.1016/J.Jmb.2007.03.079  0.681
2007 Going S, Lohman T, Cussler E, Teixeira P. Predictors of Compliance with 5-Year Follow-up Assessments in a Weight Loss Intervention Medicine & Science in Sports & Exercise. 39: S161. DOI: 10.1249/01.Mss.0000273591.70557.47  0.404
2007 Lohman T, Going S, Cussler E, Metcalfe L, Teixeira P. Predictors of Weight Regain in a Long-Term Follow-Up of a Weight Loss Intervention Medicine & Science in Sports & Exercise. 39: S160. DOI: 10.1249/01.Mss.0000273588.17193.Ff  0.403
2007 Jason Wong C, Rice RL, Baker NA, Ju T, Lohman TM. Erratum to “Probing 3′-ssDNA Loop Formation in E. coli RecBCD/RecBC–DNA Complexes Using Non-natural DNA: A Model for “Chi” Recognition Complexes” [J. Mol. Biol. 359 (2006) 1137–1149] Journal of Molecular Biology. 365: 900. DOI: 10.1016/J.Jmb.2006.07.097  0.606
2006 Eggington JM, Kozlov AG, Cox MM, Lohman TM. Polar destabilization of DNA duplexes with single-stranded overhangs by the Deinococcus radiodurans SSB protein. Biochemistry. 45: 14490-502. PMID 17128988 DOI: 10.1021/Bi061178M  0.692
2006 Kumaran S, Kozlov AG, Lohman TM. Saccharomyces cerevisiae replication protein A binds to single-stranded DNA in multiple salt-dependent modes. Biochemistry. 45: 11958-73. PMID 17002295 DOI: 10.1021/bi060994r  0.626
2006 Wong CJ, Rice RL, Baker NA, Ju T, Lohman TM. Probing 3'-ssDNA loop formation in E. coli RecBCD/RecBC-DNA complexes using non-natural DNA: a model for "Chi" recognition complexes. Journal of Molecular Biology. 362: 26-43. PMID 16901504 DOI: 10.1016/J.Jmb.2006.07.016  0.718
2006 Kuznetsov SV, Kozlov AG, Lohman TM, Ansari A. Microsecond dynamics of protein-DNA interactions: direct observation of the wrapping/unwrapping kinetics of single-stranded DNA around the E. coli SSB tetramer. Journal of Molecular Biology. 359: 55-65. PMID 16677671 DOI: 10.1016/J.Jmb.2006.02.070  0.718
2006 Kozlov AG, Lohman TM. Effects of monovalent anions on a temperature-dependent heat capacity change for Escherichia coli SSB tetramer binding to single-stranded DNA. Biochemistry. 45: 5190-205. PMID 16618108 DOI: 10.1021/bi052543x  0.621
2005 Myong S, Rasnik I, Joo C, Lohman TM, Ha T. Repetitive shuttling of a motor protein on DNA. Nature. 437: 1321-5. PMID 16251956 DOI: 10.1038/Nature04049  0.727
2005 Wong CJ, Lucius AL, Lohman TM. Energetics of DNA end binding by E.coli RecBC and RecBCD helicases indicate loop formation in the 3'-single-stranded DNA tail. Journal of Molecular Biology. 352: 765-82. PMID 16126227 DOI: 10.1016/J.Jmb.2005.07.056  0.708
2005 Brendza KM, Cheng W, Fischer CJ, Chesnik MA, Niedziela-Majka A, Lohman TM. Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain. Proceedings of the National Academy of Sciences of the United States of America. 102: 10076-81. PMID 16009938 DOI: 10.1073/Pnas.0502886102  0.673
2004 Fischer CJ, Maluf NK, Lohman TM. Mechanism of ATP-dependent translocation of E.coli UvrD monomers along single-stranded DNA. Journal of Molecular Biology. 344: 1287-309. PMID 15561144 DOI: 10.1016/J.Jmb.2004.10.005  0.702
2004 Fischer CJ, Lohman TM. ATP-dependent translocation of proteins along single-stranded DNA: models and methods of analysis of pre-steady state kinetics. Journal of Molecular Biology. 344: 1265-86. PMID 15561143 DOI: 10.1016/J.Jmb.2004.10.004  0.667
2004 Savvides SN, Raghunathan S, Fütterer K, Kozlov AG, Lohman TM, Waksman G. The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA. Protein Science : a Publication of the Protein Society. 13: 1942-7. PMID 15169953 DOI: 10.1110/Ps.04661904  0.631
2004 Lucius AL, Lohman TM. Effects of temperature and ATP on the kinetic mechanism and kinetic step-size for E.coli RecBCD helicase-catalyzed DNA unwinding. Journal of Molecular Biology. 339: 751-71. PMID 15165848 DOI: 10.1016/J.Jmb.2004.04.010  0.662
2004 Lucius AL, Wong CJ, Lohman TM. Fluorescence stopped-flow studies of single turnover kinetics of E.coli RecBCD helicase-catalyzed DNA unwinding. Journal of Molecular Biology. 339: 731-50. PMID 15165847 DOI: 10.1016/J.Jmb.2004.04.009  0.661
2004 Murphy MC, Rasnik I, Cheng W, Lohman TM, Ha T. Probing single-stranded DNA conformational flexibility using fluorescence spectroscopy. Biophysical Journal. 86: 2530-7. PMID 15041689 DOI: 10.1016/S0006-3495(04)74308-8  0.603
2004 Rasnik I, Myong S, Cheng W, Lohman TM, Ha T. DNA-binding orientation and domain conformation of the E. coli rep helicase monomer bound to a partial duplex junction: single-molecule studies of fluorescently labeled enzymes. Journal of Molecular Biology. 336: 395-408. PMID 14757053 DOI: 10.1016/J.Jmb.2003.12.031  0.697
2003 Caballero B, Clay T, Davis SM, Ethelbah B, Rock BH, Lohman T, Norman J, Story M, Stone EJ, Stephenson L, Stevens J. Pathways: a school-based, randomized controlled trial for the prevention of obesity in American Indian schoolchildren. The American Journal of Clinical Nutrition. 78: 1030-8. PMID 14594792 DOI: 10.1093/Ajcn/78.5.1030  0.421
2003 Lucius AL, Maluf NK, Fischer CJ, Lohman TM. General methods for analysis of sequential "n-step" kinetic mechanisms: application to single turnover kinetics of helicase-catalyzed DNA unwinding. Biophysical Journal. 85: 2224-39. PMID 14507688 DOI: 10.1016/S0006-3495(03)74648-7  0.605
2003 Caballero B, Himes JH, Lohman T, Davis SM, Stevens J, Evans M, Going S, Pablo J. Body composition and overweight prevalence in 1704 schoolchildren from 7 American Indian communities. The American Journal of Clinical Nutrition. 78: 308-12. PMID 12885714 DOI: 10.1093/Ajcn/78.2.308  0.42
2003 Going S, Lohman T, Houtkooper L, Metcalfe L, Flint-Wagner H, Blew R, Stanford V, Cussler E, Martin J, Teixeira P, Harris M, Milliken L, Figueroa-Galvez A, Weber J. Effects of exercise on bone mineral density in calcium-replete postmenopausal women with and without hormone replacement therapy. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 14: 637-43. PMID 12844212 DOI: 10.1007/S00198-003-1436-X  0.41
2003 Maluf NK, Ali JA, Lohman TM. Kinetic mechanism for formation of the active, dimeric UvrD helicase-DNA complex. The Journal of Biological Chemistry. 278: 31930-40. PMID 12788954 DOI: 10.1074/Jbc.M304223200  0.687
2003 Maluf NK, Fischer CJ, Lohman TM. A Dimer of Escherichia coli UvrD is the active form of the helicase in vitro. Journal of Molecular Biology. 325: 913-35. PMID 12527299 DOI: 10.1016/S0022-2836(02)01277-9  0.719
2003 Maluf NK, Lohman TM. Self-association equilibria of Escherichia coli UvrD helicase studied by analytical ultracentrifugation. Journal of Molecular Biology. 325: 889-912. PMID 12527298 DOI: 10.1016/S0022-2836(02)01276-7  0.617
2003 Tylavsky FA, Lohman T, Blunt BA, Schoeller DA, Fuerst T, Cauley JA, Nevitt MC, Visser M, Harris TB. QDR 4500A DXA overestimates fat-free mass compared with criterion methods Journal of Applied Physiology. 94: 959-965. PMID 12433854 DOI: 10.1152/Japplphysiol.00732.2002  0.424
2003 Lohman TM, Hsieh J, Maluf NK, Cheng W, Lucius AL, Fischer CJ, Brendza KM, Korolev S, Waksman G. DNA helicases, motors that move along nucleic acids: Lessons from the SF1 helicase superfamily Enzymes. 23: 303-369,III-VII. DOI: 10.1016/S1874-6047(04)80008-8  0.678
2002 Lucius AL, Vindigni A, Gregorian R, Ali JA, Taylor AF, Smith GR, Lohman TM. DNA unwinding step-size of E. coli RecBCD helicase determined from single turnover chemical quenched-flow kinetic studies. Journal of Molecular Biology. 324: 409-28. PMID 12445778 DOI: 10.1016/S0022-2836(02)01067-7  0.689
2002 Cheng W, Brendza KM, Gauss GH, Korolev S, Waksman G, Lohman TM. The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity. Proceedings of the National Academy of Sciences of the United States of America. 99: 16006-11. PMID 12441398 DOI: 10.1073/Pnas.242479399  0.7
2002 Ha T, Rasnik I, Cheng W, Babcock HP, Gauss GH, Lohman TM, Chu S. Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase. Nature. 419: 638-41. PMID 12374984 DOI: 10.1038/Nature01083  0.717
2002 Kozlov AG, Lohman TM. Kinetic mechanism of direct transfer of Escherichia coli SSB tetramers between single-stranded DNA molecules. Biochemistry. 41: 11611-27. PMID 12269804 DOI: 10.1021/bi020361m  0.625
2002 Kozlov AG, Lohman TM. Stopped-flow studies of the kinetics of single-stranded DNA binding and wrapping around the Escherichia coli SSB tetramer. Biochemistry. 41: 6032-44. PMID 11993998 DOI: 10.1021/bi020122z  0.648
2001 Cheng W, Hsieh J, Brendza KM, Lohman TM. E. coli Rep oligomers are required to initiate DNA unwinding in vitro. Journal of Molecular Biology. 310: 327-50. PMID 11428893 DOI: 10.1006/Jmbi.2001.4758  0.702
2000 Kozlov AG, Lohman TM. Large contributions of coupled protonation equilibria to the observed enthalpy and heat capacity changes for ssDNA binding to Escherichia coli SSB protein. Proteins. 8-22. PMID 11013397 DOI: 10.1002/1097-0134(2000)41:4+<8::AID-PROT20>3.0.CO;2-H  0.554
2000 Raghunathan S, Kozlov AG, Lohman TM, Waksman G. Structure of the DNA binding domain of E. coli SSB bound to ssDNA. Nature Structural Biology. 7: 648-52. PMID 10932248 DOI: 10.1038/77943  0.714
2000 Ha T, Babcock HP, Cheng W, Lohman TM, Chu S. Single molecule fluorescence study of DNA helicase activity Pacific Rim Conference On Lasers and Electro-Optics, Cleo - Technical Digest. 589-590.  0.62
1999 Ali JA, Maluf NK, Lohman TM. An oligomeric form of E. coli UvrD is required for optimal helicase activity. Journal of Molecular Biology. 293: 815-34. PMID 10543970 DOI: 10.1006/Jmbi.1999.3185  0.716
1999 Kozlov AG, Lohman TM. Adenine base unstacking dominates the observed enthalpy and heat capacity changes for the Escherichia coli SSB tetramer binding to single-stranded oligoadenylates. Biochemistry. 38: 7388-97. PMID 10353851 DOI: 10.1021/bi990309z  0.587
1999 Hsieh J, Moore KJ, Lohman TM. A two-site kinetic mechanism for ATP binding and hydrolysis by E. coli Rep helicase dimer bound to a single-stranded oligodeoxynucleotide. Journal of Molecular Biology. 288: 255-74. PMID 10329141 DOI: 10.1006/jmbi.1999.2666  0.66
1999 Zhang W, Ni H, Capp MW, Anderson CF, Lohman TM, Record MT. The importance of coulombic end effects: experimental characterization of the effects of oligonucleotide flanking charges on the strength and salt dependence of oligocation (L8+) binding to single-stranded DNA oligomers. Biophysical Journal. 76: 1008-17. PMID 9916032 DOI: 10.1016/S0006-3495(99)77265-6  0.662
1998 Caballero B, Davis S, Davis CE, Ethelbah B, Evans M, Lohman T, Stephenson L, Story M, White J. Pathways: A school-based program for the primary prevention of obesity in American Indian children. The Journal of Nutritional Biochemistry. 9: 535-543. PMID 27340341 DOI: 10.1016/S0955-2863(98)00049-7  0.424
1998 Kozlov AG, Lohman TM. Calorimetric studies of E. coli SSB protein-single-stranded DNA interactions. Effects of monovalent salts on binding enthalpy. Journal of Molecular Biology. 278: 999-1014. PMID 9600857 DOI: 10.1006/jmbi.1998.1738  0.615
1998 Lohman TM, Thorn K, Vale RD. Staying on track: common features of DNA helicases and microtubule motors. Cell. 93: 9-12. PMID 9546385 DOI: 10.1016/S0092-8674(00)81139-3  0.568
1998 Korolev S, Yao N, Lohman TM, Weber PC, Waksman G. Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Science : a Publication of the Protein Society. 7: 605-10. PMID 9541392 DOI: 10.1002/Pro.5560070309  0.511
1998 Bjornson KP, Hsieh J, Amaratunga M, Lohman TM. Kinetic mechanism for the sequential binding of two single-stranded oligodeoxynucleotides to the Escherichia coli Rep helicase dimer. Biochemistry. 37: 891-9. PMID 9454579 DOI: 10.1021/bi9719307  0.72
1997 Korolev S, Hsieh J, Gauss GH, Lohman TM, Waksman G. Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP. Cell. 90: 635-47. PMID 9288744 DOI: 10.1016/S0092-8674(00)80525-5  0.694
1997 Raghunathan S, Ricard CS, Lohman TM, Waksman G. Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 94: 6652-7. PMID 9192620 DOI: 10.1073/Pnas.94.13.6652  0.697
1997 Mascotti DP, Lohman TM. Thermodynamics of oligoarginines binding to RNA and DNA. Biochemistry. 36: 7272-9. PMID 9188729 DOI: 10.1021/Bi970272N  0.533
1997 Ferrari ME, Fang J, Lohman TM. A mutation in E. coli SSB protein (W54S) alters intra-tetramer negative cooperativity and inter-tetramer positive cooperativity for single-stranded DNA binding. Biophysical Chemistry. 64: 235-51. PMID 9127948 DOI: 10.1016/S0301-4622(96)02223-5  0.67
1997 Wong I, Lohman TM. A two-site mechanism for ATP hydrolysis by the asymmetric Rep dimer P2S as revealed by site-specific inhibition with ADP-A1F4. Biochemistry. 36: 3115-25. PMID 9115987 DOI: 10.1021/bi9621977  0.642
1997 Ali JA, Lohman TM. Kinetic measurement of the step size of DNA unwinding by Escherichia coli UvrD helicase. Science (New York, N.Y.). 275: 377-80. PMID 8994032 DOI: 10.1126/science.275.5298.377  0.69
1996 Bjornson KP, Wong I, Lohman TM. ATP hydrolysis stimulates binding and release of single stranded DNA from alternating subunits of the dimeric E. coli Rep helicase: implications for ATP-driven helicase translocation. Journal of Molecular Biology. 263: 411-22. PMID 8918597 DOI: 10.1006/jmbi.1996.0585  0.71
1996 Wong I, Lohman TM. ATPase activity of Escherichia coli Rep helicase crosslinked to single-stranded DNA: implications for ATP driven helicase translocation. Proceedings of the National Academy of Sciences of the United States of America. 93: 10051-6. PMID 8816749  0.704
1996 Lohman TM, Bjornson KP. Mechanisms of helicase-catalyzed DNA unwinding. Annual Review of Biochemistry. 65: 169-214. PMID 8811178 DOI: 10.1146/annurev.bi.65.070196.001125  0.705
1996 Bjornson KP, Moore KJ, Lohman TM. Kinetic mechanism of DNA binding and DNA-induced dimerization of the Escherichia coli Rep helicase. Biochemistry. 35: 2268-82. PMID 8652567 DOI: 10.1021/bi9522763  0.64
1996 Wong I, Moore KJ, Bjornson KP, Hsieh J, Lohman TM. ATPase activity of Escherichia coli Rep helicase is dramatically dependent on DNA ligation and protein oligomeric states. Biochemistry. 35: 5726-34. PMID 8639532 DOI: 10.1021/bi952959i  0.688
1996 Zhang W, Bond JP, Anderson CF, Lohman TM, Record MT. Large electrostatic differences in the binding thermodynamics of a cationic peptide to oligomeric and polymeric DNA. Proceedings of the National Academy of Sciences of the United States of America. 93: 2511-6. PMID 8637905 DOI: 10.1073/pnas.93.6.2511  0.625
1996 Lohman TM, Overman LB, Ferrari ME, Kozlov AG. A highly salt-dependent enthalpy change for Escherichia coli SSB protein-nucleic acid binding due to ion-protein interactions. Biochemistry. 35: 5272-9. PMID 8611514 DOI: 10.1021/Bi9527606  0.603
1995 Wong I, Lohman TM. Linkage of protein assembly to protein-DNA binding. Methods in Enzymology. 259: 95-127. PMID 8538477 DOI: 10.1016/0076-6879(95)59040-4  0.665
1995 Mascotti DP, Lohman TM. Thermodynamics of charged oligopeptide-heparin interactions. Biochemistry. 34: 2908-15. PMID 7893705 DOI: 10.1021/Bi00009A022  0.527
1994 Lohman TM, Bujalowski W. Effects of base composition on the negative cooperativity and binding mode transitions of Escherichia coli SSB-single-stranded DNA complexes. Biochemistry. 33: 6167-76. PMID 8193130 DOI: 10.1021/Bi00186A016  0.63
1994 Overman LB, Lohman TM. Linkage of pH, anion and cation effects in protein-nucleic acid equilibria. Escherichia coli SSB protein-single stranded nucleic acid interactions. Journal of Molecular Biology. 236: 165-78. PMID 8107102 DOI: 10.1006/jmbi.1994.1126  0.592
1994 Ferrari ME, Bujalowski W, Lohman TM. Co-operative binding of Escherichia coli SSB tetramers to single-stranded DNA in the (SSB)35 binding mode. Journal of Molecular Biology. 236: 106-23. PMID 8107097 DOI: 10.1006/jmbi.1994.1122  0.617
1994 Moore KJ, Lohman TM. Kinetic mechanism of adenine nucleotide binding to and hydrolysis by the Escherichia coli Rep monomer. 2. Application of a kinetic competition approach. Biochemistry. 33: 14565-78. PMID 7981218  0.625
1994 Moore KJ, Lohman TM. Kinetic mechanism of adenine nucleotide binding to and hydrolysis by the Escherichia coli Rep monomer. 1. Use of fluorescent nucleotide analogues. Biochemistry. 33: 14550-64. PMID 7981217 DOI: 10.1021/bi00252a023  0.599
1994 Lohman TM, Ferrari ME. Escherichia coli single-stranded DNA-binding protein: multiple DNA-binding modes and cooperativities. Annual Review of Biochemistry. 63: 527-70. PMID 7979247 DOI: 10.1146/annurev.bi.63.070194.002523  0.674
1994 Bjornson KP, Amaratunga M, Moore KJ, Lohman TM. Single-turnover kinetics of helicase-catalyzed DNA unwinding monitored continuously by fluorescence energy transfer. Biochemistry. 33: 14306-16. PMID 7947840 DOI: 10.1021/bi00251a044  0.674
1994 Ferrari ME, Lohman TM. Apparent heat capacity change accompanying a nonspecific protein-DNA interaction. Escherichia coli SSB tetramer binding to oligodeoxyadenylates. Biochemistry. 33: 12896-910. PMID 7947696  0.671
1993 Wong I, Lohman TM. A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions. Proceedings of the National Academy of Sciences of the United States of America. 90: 5428-32. PMID 8516284  0.597
1993 Runyon GT, Lohman TM. Kinetics of Escherichia coli helicase II-catalyzed unwinding of fully duplex and nicked circular DNA. Biochemistry. 32: 4128-38. PMID 8471620  0.679
1993 Amaratunga M, Lohman TM. Escherichia coli rep helicase unwinds DNA by an active mechanism. Biochemistry. 32: 6815-20. PMID 8392863  0.698
1993 Runyon GT, Wong I, Lohman TM. Overexpression, purification, DNA binding, and dimerization of the Escherichia coli uvrD gene product (helicase II). Biochemistry. 32: 602-12. PMID 8380701 DOI: 10.1021/bi00053a028  0.647
1993 Mascotti DP, Lohman TM. Thermodynamics of single-stranded RNA and DNA interactions with oligolysines containing tryptophan. Effects of base composition. Biochemistry. 32: 10568-79. PMID 7691177 DOI: 10.1021/Bi00091A006  0.545
1993 Lohman T. Helicase-catalyzed DNA unwinding. Journal of Biological Chemistry. 268: 2269-2272. DOI: 10.1016/S0021-9258(18)53765-0  0.453
1993 Lohman TM. Review of Wyman and Gill, Binding and Linkage: Functional Chemistry of Biological Macromolecules Biophysical Journal. 65: 1353-1354. DOI: 10.1016/S0006-3495(93)81182-2  0.523
1992 Wei TF, Bujalowski W, Lohman TM. Cooperative binding of polyamines induces the Escherichia coli single-strand binding protein-DNA binding mode transitions. Biochemistry. 31: 6166-74. PMID 1627560  0.653
1992 Wong I, Lohman TM. Allosteric effects of nucleotide cofactors on Escherichia coli Rep helicase-DNA binding. Science (New York, N.Y.). 256: 350-5. PMID 1533057  0.722
1992 Lohman TM, Mascotti DP. Nonspecific ligand-DNA equilibrium binding parameters determined by fluorescence methods. Methods in Enzymology. 212: 424-58. PMID 1518458 DOI: 10.1016/0076-6879(92)12027-N  0.589
1992 Lohman TM, Mascotti DP. Thermodynamics of ligand-nucleic acid interactions. Methods in Enzymology. 212: 400-24. PMID 1518457 DOI: 10.1016/0076-6879(92)12026-M  0.594
1992 Mascotti DP, Lohman TM. Thermodynamics of single-stranded RNA binding to oligolysines containing tryptophan. Biochemistry. 31: 8932-46. PMID 1382582 DOI: 10.1021/Bi00152A033  0.488
1992 Wong I, Chao KL, Bujalowski W, Lohman TM. DNA-induced dimerization of the Escherichia coli rep helicase. Allosteric effects of single-stranded and duplex DNA. The Journal of Biological Chemistry. 267: 7596-610. PMID 1313807  0.725
1992 Lohman TM. Escherichia coli DNA helicases: mechanisms of DNA unwinding. Molecular Microbiology. 6: 5-14. PMID 1310794  0.709
1991 Bujalowski W, Lohman TM. Monomers of the Escherichia coli SSB-1 mutant protein bind single-stranded DNA. Journal of Molecular Biology. 217: 63-74. PMID 1988680 DOI: 10.1016/0022-2836(91)90611-9  0.674
1991 Lohman TM, Bujalowski W. Thermodynamic methods for model-independent determination of equilibrium binding isotherms for protein-DNA interactions: spectroscopic approaches to monitor binding. Methods in Enzymology. 208: 258-90. PMID 1779838 DOI: 10.1016/0076-6879(91)08017-C  0.572
1991 Chao KL, Lohman TM. DNA-induced dimerization of the Escherichia coli Rep helicase. Journal of Molecular Biology. 221: 1165-81. PMID 1658335 DOI: 10.1016/0022-2836(91)90926-W  0.729
1991 Bujalowski W, Lohman TM. Monomer-tetramer equilibrium of the Escherichia coli ssb-1 mutant single strand binding protein Journal of Biological Chemistry. 266: 1616-1626. DOI: 10.1016/S0021-9258(18)52339-5  0.406
1990 Mascotti DP, Lohman TM. Thermodynamic extent of counterion release upon binding oligolysines to single-stranded nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 87: 3142-6. PMID 2326273 DOI: 10.1073/Pnas.87.8.3142  0.643
1990 Runyon GT, Bear DG, Lohman TM. Escherichia coli helicase II (UvrD) protein initiates DNA unwinding at nicks and blunt ends. Proceedings of the National Academy of Sciences of the United States of America. 87: 6383-7. PMID 2166955 DOI: 10.1073/pnas.87.16.6383  0.673
1990 Jezewska MJ, Bujalowski W, Lohman TM. Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of DNA is highly specific for duplex DNA [Erratum to document cited in CA111(7):53491c] Biochemistry. 29: 5220-5220. DOI: 10.1021/Bi00473A032  0.596
1990 Chao K, Lohman TM. DNA and nucleotide-induced conformational changes in the Escherichia coli Rep and helicase II (UvrD) proteins. Journal of Biological Chemistry. 265: 1067-1076. DOI: 10.1016/s0021-9258(19)40159-2  0.404
1989 Bujalowski W, Lohman TM, Anderson CF. On the cooperative binding of large ligands to a one-dimensional homogeneous lattice: the generalized three-state lattice model. Biopolymers. 28: 1637-43. PMID 2775853 DOI: 10.1002/bip.360280912  0.489
1989 Bujalowski W, Lohman TM. Negative co-operativity in Escherichia coli single strand binding protein-oligonucleotide interactions. II. Salt, temperature and oligonucleotide length effects Journal of Molecular Biology. 207: 269-288. PMID 2661833 DOI: 10.1016/0022-2836(89)90455-5  0.613
1989 Bujalowski W, Lohman TM. Negative co-operativity in Escherichia coli single strand binding protein-oligonucleotide interactions. I. Evidence and a quantitative model Journal of Molecular Biology. 207: 249-268. PMID 2661832 DOI: 10.1016/0022-2836(89)90454-3  0.64
1989 Jezewska MJ, Bujalowski W, Lohman TM. Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of DNA is highly specific for duplex DNA. Biochemistry. 28: 6161-4. PMID 2506924  0.637
1989 Runyon GT, Lohman TM. Escherichia coli Helicase II (UvrD) Protein Can Completely Unwind Fully Duplex Linear and Nicked Circular DNA Journal of Biological Chemistry. 264: 17502-17512. DOI: 10.1016/s0021-9258(18)71522-6  0.425
1988 Lohman TM, Bujalowski W. Negative cooperativity within individual tetramers of Escherichia coli single strand binding protein is responsible for the transition between the (SSB)35 and (SSB)56 DNA binding modes Biochemistry®. 27: 2260-2265. PMID 3289611  0.659
1988 Lohman TM, Bujalowski W, Overman LB, Wei TF. Interactions of the E. coli Single Strand Binding (SSB) protein with ss nucleic acids. Binding mode transitions and equilibrium binding studies Biochemical Pharmacology. 37: 1781-1782. PMID 3288214 DOI: 10.1016/0006-2952(88)90443-1  0.624
1988 Overman LB, Bujalowski W, Lohman TM. Equilibrium binding of Escherichia coli single-strand binding protein to single-stranded nucleic acids in the (SSB)65 binding mode. Cation and anion effects and polynucleotide specificity Biochemistry. 27: 456-471. PMID 3280021 DOI: 10.1021/Bi00401A067  0.611
1988 Bujalowski W, Overman LB, Lohman TM. Binding mode transitions of Escherichia coli single strand binding protein-single-stranded DNA complexes. Cation, anion, pH, and binding density effects. Journal of Biological Chemistry. 263: 4629-4640. DOI: 10.1016/s0021-9258(18)68829-5  0.475
1987 Bujalowski W, Lohman TM. Limited co-operativity in protein-nucleic acid interactions. A thermodynamic model for the interactions of Escherichia coli single strand binding protein with single-stranded nucleic acids in the "beaded", (SSB)65 mode Journal of Molecular Biology. 195: 897-907. PMID 3309344 DOI: 10.1016/0022-2836(87)90493-1  0.63
1986 Bujalowski W, Lohman TM. Escherichia coli single-strand binding protein forms multiple, distinct complexes with single-stranded DNA Biochemistry. 25: 7799-7802. PMID 3542037  0.672
1986 Lohman TM, Overman LB, Datta S. Salt-dependent changes in the DNA binding co-operativity of Escherichia coli single strand binding protein Journal of Molecular Biology. 187: 603-615. PMID 3519979 DOI: 10.1016/0022-2836(86)90338-4  0.669
1986 Lohman TM. Kinetics of protein-nucleic acid interactions: use of salt effects to probe mechanisms of interaction Crc Critical Reviews in Biochemistry. 19: 191-245. PMID 3512164  0.612
1986 Lohman TM, Michael Green J, Beyer RS. Large-scale overproduction and rapid purification of the Escherichia coli ssb gene product. Expression of the ssb gene under λ PL control Biochemistry. 25: 21-25. PMID 3006753  0.575
1984 Lohman TM. Kinetics and mechanism of dissociation of cooperatively bound T4 gene 32 protein-single-stranded nucleic acid complexes. 2. Changes in mechanism as a function of sodium chloride concentration and other solution variables Biochemistry. 23: 4665-4675. PMID 6388632  0.575
1984 Lohman TM. Kinetics and mechanism of dissociation of cooperatively bound T4 gene 32 protein-single-stranded nucleic acid complexes. 1. Irreversible dissociation induced by sodium chloride concentration jumps Biochemistry. 23: 4656-4665. PMID 6388631  0.579
1983 Lohman TM. Model for the irreversible dissociation kinetics of cooperatively bound protein-nucleic acid complexes Biopolymers - Peptide Science Section. 22: 1697-1713. PMID 6882871  0.522
1981 Lohman TM, Kowalczykowski SC. Kinetics and mechanism of the association of the bacteriophage T4 gene 32 (helix destabilizing) protein with single-stranded nucleic acids. Evidence for protein translocation Journal of Molecular Biology. 152: 67-109. PMID 6279865 DOI: 10.1016/0022-2836(81)90096-6  0.582
1980 Lohman TM, DeHaseth PL, Record MT. Pentalysine-deoxyribonucleic acid interactions: A model for the general effects of ion concentrations on the interactions of proteins with nucleic acids Biochemistry. 19: 3522-3530. PMID 7407056 DOI: 10.1021/Bi00556A017  0.484
1980 Lohman TM, Wensley CG, Cina J, Burgess RR, Record MT. Use of difference boundary sedimentation velocity to investigate nonspecific protein-nucleic acid interactions Biochemistry. 19: 3516-3522. PMID 6250571 DOI: 10.1021/Bi00556A016  0.702
1978 Lohman TM, DeHaseth PL, Record MT. Analysis of ion concentration effects on the kinetics of protein-nucleic acid interactions. Application to lac repressor-operator interactions Biophysical Chemistry. 8: 281-294. PMID 728535 DOI: 10.1016/0301-4622(78)80011-8  0.575
1978 Record MT, Anderson CF, Lohman TM. Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity Quarterly Reviews of Biophysics. 11: 103-178. PMID 353875 DOI: 10.1017/S003358350000202X  0.49
1978 DeHaseth PL, Lohman TM, Burgess RR, Record MT. Nonspecific interactions of Escherichia coli RNA polymerase with native and denatured DNA: Differences in the binding behavior of core and holoenzyme Biochemistry. 17: 1612-1622. PMID 350271  0.654
1978 Record MT, Lohman TM. A semiempirical extension of polyelectrolyte theory to the treatment of oligoelectrolytes: Application to oligonucleotide helix-coil transitions Biopolymers. 17: 159-166. DOI: 10.1002/Bip.1978.360170112  0.514
1977 Record MT, DeHaseth PL, Lohman TM. Interpretation of monovalent and divalent cation effects on the lac repressor-operator interaction Biochemistry. 16: 4791-4796. PMID 911790 DOI: 10.1021/Bi00641A005  0.589
1977 DeHaseth PL, Lohman TM, Record MT. Nonspecific interaction of lac repressor with DNA: An association reaction driven by counterion release Biochemistry. 16: 4783-4790. PMID 911789 DOI: 10.1021/Bi00641A004  0.629
1976 Record MT, Woodbury CP, Lohman TM. Na+ effects on transitions of DNA and polynucleotides of variable linear charge density Biopolymers. 15: 893-915. PMID 4169 DOI: 10.1002/Bip.1976.360150507  0.546
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