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Roger J. Hajjar, MD - Publications

Affiliations: 
Medicine/Cardiology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
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Year Citation  Score
2023 Gorski PA, Lee A, Lee P, Oh JG, Vangheluwe P, Ishikawa K, Hajjar R, Kho C. Identification and Characterization of p300-Mediated Lysine Residues in Cardiac SERCA2a. International Journal of Molecular Sciences. 24. PMID 36834924 DOI: 10.3390/ijms24043502  0.348
2023 Kumar M, Haghighi K, Koch S, Rubinstein J, Stillitano F, Hajjar RJ, Kranias EG, Sadayappan S. Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy. International Journal of Molecular Sciences. 24. PMID 36768995 DOI: 10.3390/ijms24032675  0.366
2022 Rogalska ME, Vafiadaki E, Erpapazoglou Z, Haghighi K, Green L, Mantzoros CS, Hajjar RJ, Tranter M, Karakikes I, Kranias EG, Stillitano F, Kafasla P, Sanoudou D. Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts. Metabolism: Clinical and Experimental. 155344. PMID 36375644 DOI: 10.1016/j.metabol.2022.155344  0.414
2022 Main A, Boguslavskyi A, Howie J, Kuo CW, Rankin A, Burton FL, Smith GL, Hajjar R, Baillie GS, Campbell KS, Shattock MJ, Fuller W. Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies. Frontiers in Physiology. 13: 1023237. PMID 36277202 DOI: 10.3389/fphys.2022.1023237  0.364
2022 Dave J, Raad N, Mittal N, Zhang L, Fargnoli A, Oh JG, Savoia ME, Hansen J, Fava M, Yin X, Theofilatos K, Ceholski D, Kohlbrenner E, Jeong D, Wills L, ... ... Hajjar RJ, et al. Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modeling a European cardiomyopathy with global impact. Cardiovascular Research. PMID 35191471 DOI: 10.1093/cvr/cvac021  0.301
2021 Kaur K, Hadas Y, Kurian AA, Żak MM, Yoo J, Mahmood A, Girard H, Komargodski R, Io T, Santini MP, Sultana N, Kabir Sharkar MT, Magadum A, Fargnoli A, Yoon S, ... ... Hajjar RJ, et al. Direct Reprogramming Induces Vascular Regeneration Post Muscle Ischemic Injury. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34332145 DOI: 10.1016/j.ymthe.2021.07.014  0.659
2021 Magadum A, Singh N, Kurian AA, Sharkar MTK, Sultana N, Chepurko E, Kaur K, Żak MM, Hadas Y, Lebeche D, Sahoo S, Hajjar R, Zangi L. Therapeutic Delivery of Pip4k2c-Modified mRNA Attenuates Cardiac Hypertrophy and Fibrosis in the Failing Heart. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2004661. PMID 34026458 DOI: 10.1002/advs.202004661  0.676
2020 Wong AO, Gurung B, Wong WS, Mak SY, Tse WW, Li CM, Lieu DK, Costa KD, Li RA, Hajjar RJ. Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues. Journal of Molecular and Cellular Cardiology. PMID 33373642 DOI: 10.1016/j.yjmcc.2020.12.014  0.327
2020 Lee MA, Raad N, Song MH, Yoo J, Lee M, Jang SP, Kwak TH, Kook H, Choi EK, Cha TJ, Hajjar RJ, Jeong D, Park WJ. The matricellular protein CCN5 prevents adverse atrial structural and electrical remodelling. Journal of Cellular and Molecular Medicine. PMID 32885578 DOI: 10.1111/jcmm.15789  0.335
2020 Magadum A, Singh N, Kurian AA, Munir I, Mehmood T, Brown K, Sharkar MTK, Chepurko E, Sassi Y, Oh JG, Lee P, Santos CXC, Gaziel-Sovran A, Zhang G, Cai CL, ... ... Hajjar RJ, et al. Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration. Circulation. PMID 32078387 DOI: 10.1161/CIRCULATIONAHA.119.043067  0.311
2020 Hadas Y, Vincek AS, Youssef E, Żak MM, Chepurko E, Sultana N, Sharkar MTK, Guo N, Komargodski R, Kurian AA, Kaur K, Magadum A, Fargnoli A, Katz MG, Hossain N, ... ... Hajjar R, et al. Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response after Myocardial Infarction. Circulation. PMID 31992066 DOI: 10.1161/Circulationaha.119.041882  0.312
2020 Mougenot N, Mika D, Czibik G, Marcos E, Abid S, Houssaini A, Vallin B, Guellich A, Mehel H, Sawaki D, Vandecasteele G, Fischmeister R, Hajjar RJ, Dubois-Randé JL, Limon I, et al. Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction. Cardiovascular Research. 115: 1778-1790. PMID 30605506 DOI: 10.1093/cvr/cvy306  0.313
2019 Chow MZ, Sadrian SN, Keung W, Geng L, Ren L, Kong CW, Wong AO, Hulot JS, Chen CS, Costa KD, Hajjar RJ, Li RA. Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues. Scientific Reports. 9: 7502. PMID 31097748 DOI: 10.1038/S41598-019-42953-W  0.307
2019 Chen J, Strauss B, Liang L, Hajjar RJ. Animal model of left atrial thrombus in congestive heart failure in rats. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31074653 DOI: 10.1152/ajpheart.00086.2019  0.317
2019 LaRocca TJ, Altman P, Jarrah AA, Gordon R, Wang E, Hadri L, Burke MW, Haddad GE, Hajjar RJ, Tarzami ST. CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy. International Journal of Molecular Sciences. 20. PMID 31071921 DOI: 10.3390/Ijms20092267  0.411
2019 Santos-Gallego CG, Requena-Ibanez JA, San Antonio R, Ishikawa K, Watanabe S, Picatoste B, Flores E, Garcia-Ropero A, Sanz J, Hajjar RJ, Fuster V, Badimon JJ. Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics. Journal of the American College of Cardiology. 73: 1931-1944. PMID 30999996 DOI: 10.1016/j.jacc.2019.01.056  0.316
2019 Gorski PA, Jang SP, Jeong D, Lee A, Lee P, Oh JG, Chepurko V, Yang DK, Kwak TH, Eom SH, Park ZY, Yoo YJ, Kim DH, Kook H, Sunagawa Y, ... ... Hajjar RJ, et al. Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca-ATPase in Heart Failure. Circulation Research. PMID 30786847 DOI: 10.1161/CIRCRESAHA.118.313865  0.329
2019 Oh JG, Jang SP, Yoo J, Lee MA, Lee SH, Lim T, Jeong E, Kho C, Kook H, Hajjar RJ, Park WJ, Jeong D. Role of the PRC2-Six1-miR-25 signaling axis in heart failure. Journal of Molecular and Cellular Cardiology. PMID 30771307 DOI: 10.1016/j.yjmcc.2019.01.017  0.317
2019 Chaanine AH, Joyce LD, Stulak JM, Maltais S, Joyce DL, Dearani JA, Klaus K, Nair KS, Hajjar RJ, Redfield MM. Mitochondrial Morphology, Dynamics, and Function in Human Pressure Overload or Ischemic Heart Disease With Preserved or Reduced Ejection Fraction. Circulation. Heart Failure. 12: e005131. PMID 30744415 DOI: 10.1161/Circheartfailure.118.005131  0.317
2018 Oh JG, Watanabe S, Lee A, Gorski PA, Lee P, Jeong D, Liang L, Liang Y, Baccarini A, Sahoo S, Brown BD, Hajjar RJ, Kho C. miR-146a Suppresses SUMO1 Expression and Induces Cardiac Dysfunction in Maladaptive Hypertrophy. Circulation Research. 123: 673-685. PMID 30355233 DOI: 10.1161/CIRCRESAHA.118.312751  0.379
2018 Singh R, Moreno P, Hajjar RJ, Lebeche D. A role for calcium in resistin transcriptional activation in diabetic hearts. Scientific Reports. 8: 15633. PMID 30353146 DOI: 10.1038/s41598-018-34112-4  0.675
2018 Katz MG, Fargnoli AS, Yarnall C, Perez A, Isidro A, Hajjar RJ, Bridges CR. Technique of Complete Heart Isolation with Continuous Cardiac Perfusion During Cardiopulmonary Bypass: New Opportunities for Gene Therapy. The Journal of Extra-Corporeal Technology. 50: 193-198. PMID 30250349  0.319
2018 Mathiyalagan P, Adamiak M, Mayourian J, Sassi Y, Liang Y, Agarwal N, Jha D, Zhang S, Kohlbrenner E, Chepurko E, Chen J, Trivieri MG, Singh R, Bouchareb R, Fish K, ... ... Hajjar RJ, et al. FTO-Dependent m6A Regulates Cardiac Function During Remodeling and Repair. Circulation. PMID 29997116 DOI: 10.1161/CIRCULATIONAHA.118.033794  0.717
2018 Watanabe S, Bikou O, Hajjar RJ, Ishikawa K. Swine Model of Mitral Regurgitation Induced Heart Failure. Methods in Molecular Biology (Clifton, N.J.). 1816: 327-335. PMID 29987831 DOI: 10.1007/978-1-4939-8597-5_25  0.327
2018 Bikou O, Watanabe S, Hajjar RJ, Ishikawa K. A Pig Model of Myocardial Infarction: Catheter-Based Approaches. Methods in Molecular Biology (Clifton, N.J.). 1816: 281-294. PMID 29987828 DOI: 10.1007/978-1-4939-8597-5_22  0.318
2018 Yoo J, Chepurko V, Hajjar RJ, Jeong D. Conventional Method of Transverse Aortic Constriction in Mice. Methods in Molecular Biology (Clifton, N.J.). 1816: 183-193. PMID 29987820 DOI: 10.1007/978-1-4939-8597-5_14  0.34
2018 Asensio-Lopez MDC, Lax Perez A, Fernandez Del Palacio MJ, Sassi Y, Hajjar RJ, Pascual-Figal DA. Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKCα/Gal-3 pathway reduces left ventricular fibrosis following myocardial infarction. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 29753686 DOI: 10.1016/j.trsl.2018.04.004  0.375
2018 Gordon HP, Katz MG, Fargnoli AS, Gillespie VL, Hajjar RJ, Bridges CR. Scar Size and Other Parameters for Tracking Left Ventricular Dysfunction after Induction of Myocardial Infarcts in Sheep (Ovis aries). Comparative Medicine. PMID 29747722 DOI: 10.30802/Aalas-Cm-17-000040  0.353
2018 Rodriguez P, Sassi Y, Troncone L, Benard L, Ishikawa K, Gordon RE, Lamas S, Laborda J, Hajjar RJ, Lebeche D. Deletion of delta-like 1 homologue accelerates fibroblast-myofibroblast differentiation and induces myocardial fibrosis. European Heart Journal. PMID 29668883 DOI: 10.1093/eurheartj/ehy188  0.681
2018 Chamberlain K, Riyad JM, Garnett T, Kohlbrenner E, Mookerjee A, Elmastour F, Benard L, Chen J, VandenDriessche T, Chuah MKL, Marian AJ, Hajjar R, Gurha P, Weber T. A calsequestrin cis-regulatory motif coupled to a cardiac troponin T promoter improves cardiac AAV9 transduction specificity. Human Gene Therapy. PMID 29641321 DOI: 10.1089/hum.2017.188  0.333
2018 Watanabe S, Fish K, Kovacic JC, Bikou O, Leonardson L, Nomoto K, Aguero J, Kapur NK, Hajjar RJ, Ishikawa K. Left Ventricular Unloading Using an Impella CP Improves Coronary Flow and Infarct Zone Perfusion in Ischemic Heart Failure. Journal of the American Heart Association. 7. PMID 29514806 DOI: 10.1161/JAHA.117.006462  0.315
2018 Kawai H, Chaudhry F, Shekhar A, Petrov A, Nakahara T, Tanimoto T, Kim D, Chen J, Lebeche D, Blankenberg FG, Pak KY, Kolodgie FD, Virmani R, Sengupta P, Narula N, ... Hajjar RJ, et al. Molecular Imaging of Apoptosis in Ischemia Reperfusion Injury With Radiolabeled Duramycin Targeting Phosphatidylethanolamine: Effective Target Uptake and Reduced Nontarget Organ Radiation Burden. Jacc. Cardiovascular Imaging. PMID 29454770 DOI: 10.1016/j.jcmg.2017.11.037  0.577
2018 Mayourian J, Ceholski DK, Gonzalez DM, Cashman TJ, Sahoo S, Hajjar RJ, Costa KD. Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling. Circulation Research. 122: 167-183. PMID 29301848 DOI: 10.1161/Circresaha.117.311589  0.347
2018 Jarrah AA, Schwarskopf M, Wang ER, LaRocca T, Dhume A, Zhang S, Hadri L, Hajjar RJ, Schecter AD, Tarzami ST. SDF-1 induces TNF-mediated apoptosis in cardiac myocytes. Apoptosis : An International Journal On Programmed Cell Death. 23: 79-91. PMID 29236198 DOI: 10.1007/S10495-017-1438-3  0.301
2018 Hajjar RJ, Ishikawa K. Introducing Genes to the Heart: All About Delivery. Circulation Research. 120: 33-35. PMID 28057788 DOI: 10.1161/CIRCRESAHA.116.310039  0.304
2017 Katz MG, Fargnoli AS, Hajjar RJ, Bridges CR. Heart Isolation Featuring Closed Loop Recirculation: The Gold Standard for Optimum Cardiac Gene Transfer? Advanced Techniques in Biology & Medicine. 5. PMID 29682631 DOI: 10.4172/2379-1764.1000241  0.347
2017 Bidwell PA, Liu GS, Nagarajan N, Lam CK, Haghighi K, Gardner G, Cai WF, Zhao W, Mugge L, Vafiadaki E, Sanoudou D, Rubinstein J, Lebeche D, Hajjar R, Sadoshima J, et al. HAX-1 regulates SERCA2a oxidation and degradation. Journal of Molecular and Cellular Cardiology. PMID 29169992 DOI: 10.1016/J.Yjmcc.2017.11.014  0.666
2017 Watanabe S, Ishikawa K, Fish K, Oh JG, Motloch LJ, Kohlbrenner E, Lee P, Xie C, Lee A, Liang L, Kho C, Leonardson L, McIntyre M, Wilson S, Samulski RJ, ... ... Hajjar RJ, et al. Protein Phosphatase Inhibitor-1 Gene Therapy in a Swine Model of Nonischemic Heart Failure. Journal of the American College of Cardiology. 70: 1744-1756. PMID 28958332 DOI: 10.1016/J.Jacc.2017.08.013  0.369
2017 Motloch LJ, Ishikawa K, Xie C, Hu J, Aguero J, Fish KM, Hajjar RJ, Akar FG. Increased afterload following myocardial infarction promotes conduction-dependent arrhythmias that are unmasked by hypokalemia. Jacc. Basic to Translational Science. 2: 258-269. PMID 28798965 DOI: 10.1016/j.jacbts.2017.02.002  0.32
2017 Katz MG, Fargnoli AS, Weber T, Hajjar R, Bridges C. Use of Adeno-Associated Virus Vector for Cardiac Gene Delivery in Large Animal Surgical Models of Heart Failure. Human Gene Therapy. Clinical Development. PMID 28726495 DOI: 10.1089/Humc.2017.070  0.334
2017 Hammoudi N, Jeong D, Singh R, Farhat A, Komajda M, Mayoux E, Hajjar R, Lebeche D. Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes. Cardiovascular Drugs and Therapy. PMID 28643218 DOI: 10.1007/s10557-017-6734-1  0.665
2017 Mayourian J, Cashman TJ, Ceholski DK, Johnson BV, Sachs D, Kaji DA, Sahoo S, Hare JM, Hajjar RJ, Sobie EA, Costa KD. Experimental and Computational Insight into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity. Circulation Research. PMID 28642329 DOI: 10.1161/Circresaha.117.310796  0.313
2017 Hulot JS, Salem JE, Redheuil A, Collet JP, Varnous S, Jourdain P, Logeart D, Gandjbakhch E, Bernard C, Hatem SN, Isnard R, Cluzel P, Le Feuvre C, Leprince P, Hammoudi N, ... ... Hajjar RJ, et al. Effect of intracoronary administration of AAV1/SERCA2a on ventricular remodelling in patients with advanced systolic heart failure: results from the AGENT-HF randomized phase 2 trial. European Journal of Heart Failure. PMID 28393439 DOI: 10.1002/ejhf.826  0.378
2017 Sultana N, Magadum A, Hadas Y, Kondrat J, Singh N, Youssef E, Calderon D, Chepurko E, Dubois N, Hajjar RJ, Zangi L. Optimizing Cardiac Delivery of Modified mRNA. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28389322 DOI: 10.1016/j.ymthe.2017.03.016  0.358
2017 Lebeche D, Hajjar R. Candesartan abrogates G protein-coupled receptors agonist-induced MAPK activation and cardiac myocyte hypertrophy. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 2: S154-S161. PMID 28095237 DOI: 10.1177/14703203010020012701  0.628
2016 Chen J, Hammoudi N, Benard L, Ceholski DK, Zhang S, Lebeche D, Hajjar RJ. The Probability of Inconstancy in Assessment of Cardiac Function Post-Myocardial Infarction in Mice. Cardiovascular Pharmacology: Open Access. 5. PMID 27917392  0.658
2016 Chaanine AH, Kohlbrenner E, Gamb SI, Guenzel AJ, Klaus KA, Fayyaz AU, Nair KS, Hajjar RJ, Redfield MM. FOXO3a Regulates BNIP3 and Modulates Mitochondrial Calcium, Dynamics and Function in Cardiac Stress. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00549.2016. PMID 27694219 DOI: 10.1152/Ajpheart.00549.2016  0.313
2016 Yan J, Zhang L, Sultana N, Oh JG, Wu B, Hajjar RJ, Zhou B, Cai CL. A series of robust genetic indicators for definitive identification of cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 27266388 DOI: 10.1016/j.yjmcc.2016.06.003  0.372
2016 Jeong D, Lee MA, Li Y, Yang DK, Kho C, Oh JG, Hong G, Lee A, Song MH, LaRocca TJ, Chen J, Liang L, Mitsuyama S, D'Escamard V, Kovacic JC, ... ... Hajjar RJ, et al. Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis. Journal of the American College of Cardiology. 67: 1556-68. PMID 27150688 DOI: 10.1016/J.Jacc.2016.01.030  0.368
2016 Bénard L, Oh JG, Cacheux M, Lee A, Nonnenmacher M, Matasic DS, Kohlbrenner E, Kho C, Pavoine C, Hajjar RJ, Hulot JS. Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling. Circulation. PMID 26936863 DOI: 10.1161/CIRCULATIONAHA.115.020678  0.344
2015 Lee A, Oh JG, Gorski PA, Hajjar RJ, Kho C. Post-translational Modifications in Heart Failure: Small Changes, Big Impact. Heart, Lung & Circulation. PMID 26795636 DOI: 10.1016/j.hlc.2015.11.008  0.335
2015 Katz MG, Brandon-Warner E, Fargnoli AS, Williams RD, Kendle AP, Hajjar RJ, Schrum LW, Bridges CR. Mitigation of myocardial fibrosis by molecular cardiac surgery-mediated gene overexpression. The Journal of Thoracic and Cardiovascular Surgery. PMID 26769537 DOI: 10.1016/J.Jtcvs.2015.11.031  0.38
2015 Katz MG, Fargnoli AS, Kendle AP, Hajjar RJ, Bridges CR. The Role of microRNAs in Cardiac Development and Regenerative Capacity. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00181.2015. PMID 26702142 DOI: 10.1152/Ajpheart.00181.2015  0.33
2015 Kang S, Dahl R, Hsieh W, Shin AC, Zsebo KM, Buettner C, Hajjar RJ, Lebeche D. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders. The Journal of Biological Chemistry. PMID 26702054 DOI: 10.1074/Jbc.M115.705012  0.618
2015 Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S, Jeong D, Sheng W, Bu L, Xu M, Huang GY, Hajjar RJ, Zhou B, Moon A, Cai CL. Resident c-kit(+) cells in the heart are not cardiac stem cells. Nature Communications. 6: 8701. PMID 26515110 DOI: 10.1038/ncomms9701  0.334
2015 Turnbull IC, Eltoukhy AA, Fish KM, Nonnenmacher M, Ishikawa K, Chen J, Hajjar RJ, Anderson DG, Costa KD. Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26471463 DOI: 10.1038/Mt.2015.193  0.318
2015 Haghighi K, Pritchard TJ, Liu GS, Singh VP, Bidwell P, Lam CK, Vafiadaki E, Das P, Ma J, Kunduri S, Sanoudou D, Florea S, Vanderbilt E, Wang HS, Rubinstein J, ... Hajjar RJ, et al. Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. Journal of Molecular and Cellular Cardiology. PMID 26455482 DOI: 10.1016/J.Yjmcc.2015.10.004  0.354
2015 Ramos-Kuri M, Rapti K, Mehel H, Zhang S, Dhandapany PS, Liang L, García-Carrancá A, Bobe R, Fischmeister R, Adnot S, Lebeche D, Hajjar RJ, Lipskaia L, Chemaly ER. Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy. Biochimica Et Biophysica Acta. PMID 26260012 DOI: 10.1016/j.bbamcr.2015.08.006  0.605
2015 Cai WF, Liu GS, Lam CK, Florea S, Qian J, Zhao W, Pritchard T, Haghighi K, Lebeche D, Lu LJ, Deng J, Fan GC, Hajjar RJ, Kranias EG. Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility. European Journal of Heart Failure. 17: 782-93. PMID 26177627 DOI: 10.1002/Ejhf.323  0.657
2015 Chaanine AH, Gordon RE, Nonnenmacher M, Kohlbrenner E, Benard L, Hajjar RJ. High-dose chloroquine is metabolically cardiotoxic by inducing lysosomes and mitochondria dysfunction in a rat model of pressure overload hypertrophy. Physiological Reports. 3. PMID 26152691 DOI: 10.14814/phy2.12413  0.301
2015 Kho C, Lee A, Jeong D, Oh JG, Gorski PA, Fish K, Sanchez R, DeVita RJ, Christensen G, Dahl R, Hajjar RJ. Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nature Communications. 6: 7229. PMID 26068603 DOI: 10.1038/Ncomms8229  0.382
2015 Ishikawa K, Aguero J, Tilemann L, Ladage D, Hammoudi N, Kawase Y, Santos-Gallego CG, Fish K, Levine RA, Hajjar RJ. Reply to "Letter to the editor: Characterizing preclinical model of ischemic heart failure: difference between LAD and LCx infarctions". American Journal of Physiology. Heart and Circulatory Physiology. 308: H365-6. PMID 25684739 DOI: 10.1152/Ajpheart.00855.2014  0.32
2015 Ishikawa K, Fish K, Aguero J, Yaniz-Galende E, Jeong D, Kho C, Tilemann L, Fish L, Liang L, Eltoukhy AA, Anderson DG, Zsebo K, Costa KD, Hajjar RJ. Stem cell factor gene transfer improves cardiac function after myocardial infarction in swine. Circulation. Heart Failure. 8: 167-74. PMID 25342737 DOI: 10.1161/Circheartfailure.114.001711  0.331
2014 Lipskaia L, Keuylian Z, Blirando K, Mougenot N, Jacquet A, Rouxel C, Sghairi H, Elaib Z, Blaise R, Adnot S, Hajjar RJ, Chemaly ER, Limon I, Bobe R. Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis. Biochimica Et Biophysica Acta. 1843: 2705-18. PMID 25110346 DOI: 10.1016/j.bbamcr.2014.08.002  0.305
2014 Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, ... ... Hajjar RJ, et al. Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2038-45. PMID 25023328 DOI: 10.1038/Mt.2014.127  0.377
2014 Lee A, Jeong D, Mitsuyama S, Oh JG, Liang L, Ikeda Y, Sadoshima J, Hajjar RJ, Kho C. The role of SUMO-1 in cardiac oxidative stress and hypertrophy. Antioxidants & Redox Signaling. 21: 1986-2001. PMID 24893265 DOI: 10.1089/ars.2014.5983  0.369
2014 Dhandapany PS, Razzaque MA, Muthusami U, Kunnoth S, Edwards JJ, Mulero-Navarro S, Riess I, Pardo S, Sheng J, Rani DS, Rani B, Govindaraj P, Flex E, Yokota T, Furutani M, ... ... Hajjar RJ, et al. RAF1 mutations in childhood-onset dilated cardiomyopathy. Nature Genetics. 46: 635-9. PMID 24777450 DOI: 10.1038/Ng.2963  0.623
2014 Wahlquist C, Jeong D, Rojas-Muñoz A, Kho C, Lee A, Mitsuyama S, van Mil A, Park WJ, Sluijter JP, Doevendans PA, Hajjar RJ, Mercola M. Inhibition of miR-25 improves cardiac contractility in the failing heart. Nature. 508: 531-5. PMID 24670661 DOI: 10.1038/Nature13073  0.334
2014 Greenberg B, Yaroshinsky A, Zsebo KM, Butler J, Felker GM, Voors AA, Rudy JJ, Wagner K, Hajjar RJ. Design of a phase 2b trial of intracoronary administration of AAV1/SERCA2a in patients with advanced heart failure: the CUPID 2 trial (calcium up-regulation by percutaneous administration of gene therapy in cardiac disease phase 2b). Jacc. Heart Failure. 2: 84-92. PMID 24622121 DOI: 10.1016/j.jchf.2013.09.008  0.319
2014 Chaanine AH, Nonnenmacher M, Kohlbrenner E, Jin D, Kovacic JC, Akar FG, Hajjar RJ, Weber T. Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure. Gene Therapy. 21: 379-86. PMID 24572786 DOI: 10.1038/gt.2014.7  0.348
2014 Akar FG, Hajjar RJ. Gene therapies for arrhythmias in heart failure. PflüGers Archiv : European Journal of Physiology. 466: 1211-7. PMID 24566976 DOI: 10.1007/s00424-014-1485-3  0.317
2014 Turnbull IC, Karakikes I, Serrao GW, Backeris P, Lee JJ, Xie C, Senyei G, Gordon RE, Li RA, Akar FG, Hajjar RJ, Hulot JS, Costa KD. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 644-54. PMID 24174427 DOI: 10.1096/Fj.13-228007  0.32
2014 Yerevanian A, Yerevanian A, Hajjar RJ. Progress in gene therapy for heart failure. Journal of Cardiovascular Pharmacology. 63: 95-106. PMID 23921315 DOI: 10.1097/FJC.0b013e3182a2e8b8  0.342
2013 Pritchard TJ, Kawase Y, Haghighi K, Anjak A, Cai W, Jiang M, Nicolaou P, Pylar G, Karakikes I, Rapti K, Rubinstein J, Hajjar RJ, Kranias EG. Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts. Plos One. 8: e80717. PMID 24312496 DOI: 10.1371/Journal.Pone.0080717  0.407
2013 Tilemann L, Lee A, Ishikawa K, Aguero J, Rapti K, Santos-Gallego C, Kohlbrenner E, Fish KM, Kho C, Hajjar RJ. SUMO-1 gene transfer improves cardiac function in a large-animal model of heart failure. Science Translational Medicine. 5: 211ra159. PMID 24225946 DOI: 10.1126/scitranslmed.3006487  0.405
2013 Chemaly ER, Kang S, Zhang S, McCollum L, Chen J, Bénard L, Purushothaman KR, Hajjar RJ, Lebeche D. Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin. The Journal of Physiology. 591: 5337-55. PMID 24018949 DOI: 10.1113/jphysiol.2013.258731  0.645
2013 Fargnoli AS, Katz MG, Yarnall C, Isidro A, Petrov M, Steuerwald N, Ghosh S, Richardville KC, Hillesheim R, Williams RD, Kohlbrenner E, Stedman HH, Hajjar RJ, Bridges CR. Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure. The Annals of Thoracic Surgery. 96: 586-95. PMID 23773730 DOI: 10.1016/J.Athoracsur.2013.04.021  0.385
2013 Karakikes I, Chaanine AH, Kang S, Mukete BN, Jeong D, Zhang S, Hajjar RJ, Lebeche D. Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling. Journal of the American Heart Association. 2: e000078. PMID 23612897 DOI: 10.1161/JAHA.113.000078  0.662
2013 Chaanine AH, Gordon RE, Kohlbrenner E, Benard L, Jeong D, Hajjar RJ. Potential role of BNIP3 in cardiac remodeling, myocardial stiffness, and endoplasmic reticulum: mitochondrial calcium homeostasis in diastolic and systolic heart failure. Circulation. Heart Failure. 6: 572-83. PMID 23508759 DOI: 10.1161/CIRCHEARTFAILURE.112.000200  0.372
2013 Chemaly ER, Hajjar RJ, Lipskaia L. Molecular targets of current and prospective heart failure therapies. Heart (British Cardiac Society). 99: 992-1003. PMID 23349349 DOI: 10.1136/heartjnl-2012-302970  0.3
2013 Naim C, Yerevanian A, Hajjar RJ. Gene therapy for heart failure: where do we stand? Current Cardiology Reports. 15: 333. PMID 23307169 DOI: 10.1007/s11886-012-0333-3  0.314
2013 Hajjar RJ. Potential of gene therapy as a treatment for heart failure. The Journal of Clinical Investigation. 123: 53-61. PMID 23281410 DOI: 10.1172/JCI62837  0.314
2013 Fish KM, Ladage D, Kawase Y, Karakikes I, Jeong D, Ly H, Ishikawa K, Hadri L, Tilemann L, Muller-Ehmsen J, Samulski RJ, Kranias EG, Hajjar RJ. AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling. Circulation. Heart Failure. 6: 310-7. PMID 23271792 DOI: 10.1161/Circheartfailure.112.971325  0.418
2013 Kratlian RG, Hajjar RJ. Cardiac gene therapy: from concept to reality. Current Heart Failure Reports. 9: 33-9. PMID 22143928 DOI: 10.1007/s11897-011-0077-1  0.324
2012 Balderman JA, Lee HY, Mahoney CE, Handy DE, White K, Annis S, Lebeche D, Hajjar RJ, Loscalzo J, Leopold JA. Bone morphogenetic protein-2 decreases microRNA-30b and microRNA-30c to promote vascular smooth muscle cell calcification. Journal of the American Heart Association. 1: e003905. PMID 23316327 DOI: 10.1161/Jaha.112.003905  0.578
2012 Kho C, Lee A, Hajjar RJ. Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy. Nature Reviews. Cardiology. 9: 717-33. PMID 23090087 DOI: 10.1038/nrcardio.2012.145  0.303
2012 Cutler MJ, Wan X, Plummer BN, Liu H, Deschenes I, Laurita KR, Hajjar RJ, Rosenbaum DS. Targeted sarcoplasmic reticulum Ca2+ ATPase 2a gene delivery to restore electrical stability in the failing heart. Circulation. 126: 2095-104. PMID 23019291 DOI: 10.1161/Circulationaha.111.071480  0.399
2012 Park CS, Cha H, Kwon EJ, Jeong D, Hajjar RJ, Kranias EG, Cho C, Park WJ, Kim DH. AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure Plos One. 7. PMID 22952658 DOI: 10.1371/Journal.Pone.0043282  0.393
2012 Kranias EG, Hajjar RJ. Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circulation Research. 110: 1646-60. PMID 22679139 DOI: 10.1161/Circresaha.111.259754  0.364
2012 Larocca TJ, Jeong D, Kohlbrenner E, Lee A, Chen J, Hajjar RJ, Tarzami ST. CXCR4 gene transfer prevents pressure overload induced heart failure. Journal of Molecular and Cellular Cardiology. 53: 223-32. PMID 22668785 DOI: 10.1016/J.Yjmcc.2012.05.016  0.438
2012 LaRocca TJ, Fabris F, Chen J, Benhayon D, Zhang S, McCollum L, Schecter AD, Cheung JY, Sobie EA, Hajjar RJ, Lebeche D. Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway. American Journal of Physiology. Heart and Circulatory Physiology. 303: H353-67. PMID 22610174 DOI: 10.1152/Ajpheart.01198.2011  0.716
2012 Kairouz V, Lipskaia L, Hajjar RJ, Chemaly ER. Molecular targets in heart failure gene therapy: current controversies and translational perspectives. Annals of the New York Academy of Sciences. 1254: 42-50. PMID 22548568 DOI: 10.1111/j.1749-6632.2012.06520.x  0.302
2012 Sun N, Yazawa M, Liu J, Han L, Sanchez-Freire V, Abilez OJ, Navarrete EG, Hu S, Wang L, Lee A, Pavlovic A, Lin S, Chen R, Hajjar RJ, Snyder MP, et al. Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Science Translational Medicine. 4: 130ra47. PMID 22517884 DOI: 10.1126/Scitranslmed.3003552  0.326
2012 Tilemann L, Ishikawa K, Weber T, Hajjar RJ. Gene therapy for heart failure. Circulation Research. 110: 777-93. PMID 22383712 DOI: 10.1161/CIRCRESAHA.111.252981  0.311
2012 Kumarswamy R, Lyon AR, Volkmann I, Mills AM, Bretthauer J, Pahuja A, Geers-Knörr C, Kraft T, Hajjar RJ, Macleod KT, Harding SE, Thum T. SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway. European Heart Journal. 33: 1067-75. PMID 22362515 DOI: 10.1093/Eurheartj/Ehs043  0.397
2012 Karakikes I, Hadri L, Rapti K, Ladage D, Ishikawa K, Tilemann L, Yi GH, Morel C, Gwathmey JK, Zsebo K, Weber T, Kawase Y, Hajjar RJ. Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts Molecular Therapy. 20: 565-571. PMID 22215018 DOI: 10.1038/mt.2011.268  0.346
2012 Lee SH, Kim J, Ryu JY, Lee S, Yang DK, Jeong D, Kim J, Lee SH, Kim JM, Hajjar RJ, Park WJ. Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy. Journal of Molecular and Cellular Cardiology. 52: 718-26. PMID 22197309 DOI: 10.1016/j.yjmcc.2011.12.002  0.305
2011 Ladage D, Tilemann L, Ishikawa K, Correll RN, Kawase Y, Houser SR, Molkentin JD, Hajjar RJ. Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury. Circulation Research. 109: 1396-400. PMID 21998327 DOI: 10.1161/Circresaha.111.255687  0.411
2011 Kho C, Lee A, Jeong D, Oh JG, Chaanine AH, Kizana E, Park WJ, Hajjar RJ. SUMO1-dependent modulation of SERCA2a in heart failure. Nature. 477: 601-5. PMID 21900893 DOI: 10.1038/nature10407  0.443
2011 Shin JH, Bostick B, Yue Y, Hajjar R, Duan D. SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice. Journal of Translational Medicine. 9: 132. PMID 21834967 DOI: 10.1186/1479-5876-9-132  0.322
2011 Chaanine AH, Hajjar RJ. AKT signalling in the failing heart. European Journal of Heart Failure. 13: 825-9. PMID 21724622 DOI: 10.1093/eurjhf/hfr080  0.321
2011 Jessup M, Greenberg B, Mancini D, Cappola T, Pauly DF, Jaski B, Yaroshinsky A, Zsebo KM, Dittrich H, Hajjar RJ. Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure. Circulation. 124: 304-13. PMID 21709064 DOI: 10.1161/CIRCULATIONAHA.111.022889  0.306
2011 Chen J, Chemaly ER, Liang LF, LaRocca TJ, Yaniz-Galende E, Hajjar RJ. A new model of congestive heart failure in rats. American Journal of Physiology. Heart and Circulatory Physiology. 301: H994-1003. PMID 21685270 DOI: 10.1152/Ajpheart.00245.2011  0.363
2011 Ishikawa K, Ladage D, Tilemann L, Fish K, Kawase Y, Hajjar RJ. Gene transfer for ischemic heart failure in a preclinical model Journal of Visualized Experiments : Jove. PMID 21633324 DOI: 10.3791/2778  0.359
2011 Rapti K, Chaanine AH, Hajjar RJ. Targeted gene therapy for the treatment of heart failure. The Canadian Journal of Cardiology. 27: 265-83. PMID 21601767 DOI: 10.1016/j.cjca.2011.02.005  0.341
2011 Chemaly ER, Hadri L, Zhang S, Kim M, Kohlbrenner E, Sheng J, Liang L, Chen J, K-Raman P, Hajjar RJ, Lebeche D. Long-term in vivo resistin overexpression induces myocardial dysfunction and remodeling in rats. Journal of Molecular and Cellular Cardiology. 51: 144-55. PMID 21549710 DOI: 10.1016/j.yjmcc.2011.04.006  0.628
2011 Kang S, Chemaly ER, Hajjar RJ, Lebeche D. Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways. The Journal of Biological Chemistry. 286: 18465-73. PMID 21478152 DOI: 10.1074/jbc.M110.200022  0.66
2011 Dhandapany PS, Fabris F, Tonk R, Illaste A, Karakikes I, Sorourian M, Sheng J, Hajjar RJ, Tartaglia M, Sobie EA, Lebeche D, Gelb BD. Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes. Journal of Molecular and Cellular Cardiology. 51: 4-15. PMID 21440552 DOI: 10.1016/J.Yjmcc.2011.03.001  0.663
2011 Lyon AR, Bannister ML, Collins T, Pearce E, Sepehripour AH, Dubb SS, Garcia E, O'Gara P, Liang L, Kohlbrenner E, Hajjar RJ, Peters NS, Poole-Wilson PA, Macleod KT, Harding SE. SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure. Circulation. Arrhythmia and Electrophysiology. 4: 362-72. PMID 21406682 DOI: 10.1161/Circep.110.961615  0.349
2011 Kawase Y, Ladage D, Hajjar RJ. Rescuing the failing heart by targeted gene transfer. Journal of the American College of Cardiology. 57: 1169-80. PMID 21371634 DOI: 10.1016/j.jacc.2010.11.023  0.316
2010 Gwathmey JK, Yerevanian AI, Hajjar RJ. Cardiac gene therapy with SERCA2a: from bench to bedside. Journal of Molecular and Cellular Cardiology. 50: 803-12. PMID 21093451 DOI: 10.1016/j.yjmcc.2010.11.011  0.345
2010 Njeim MT, Hajjar RJ. Gene therapy for heart failure. Archives of Cardiovascular Diseases. 103: 477-85. PMID 21074127 DOI: 10.1016/j.acvd.2010.04.004  0.326
2010 Peña JR, Szkudlarek AC, Warren CM, Heinrich LS, Gaffin RD, Jagatheesan G, del Monte F, Hajjar RJ, Goldspink PH, Solaro RJ, Wieczorek DF, Wolska BM. Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 49: 993-1002. PMID 20854827 DOI: 10.1016/J.Yjmcc.2010.09.010  0.35
2010 Chen G, Zhou X, Florea S, Qian J, Cai W, Zhang Z, Fan GC, Lorenz J, Hajjar RJ, Kranias EG. Expression of active protein phosphatase 1 inhibitor-1 attenuates chronic beta-agonist-induced cardiac apoptosis. Basic Research in Cardiology. 105: 573-81. PMID 20512582 DOI: 10.1007/S00395-010-0106-3  0.305
2010 Hadri L, Bobe R, Kawase Y, Ladage D, Ishikawa K, Atassi F, Lebeche D, Kranias EG, Leopold JA, Lompré AM, Lipskaia L, Hajjar RJ. SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells Molecular Therapy. 18: 1284-1292. PMID 20461063 DOI: 10.1038/Mt.2010.77  0.656
2010 Yoon PO, Lee MA, Cha H, Jeong MH, Kim J, Jang SP, Choi BY, Jeong D, Yang DK, Hajjar RJ, Park WJ. The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosis. Journal of Molecular and Cellular Cardiology. 49: 294-303. PMID 20430035 DOI: 10.1016/j.yjmcc.2010.04.010  0.321
2010 Chen J, Chemaly E, Liang L, Kho C, Lee A, Park J, Altman P, Schecter AD, Hajjar RJ, Tarzami ST. Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury. The American Journal of Pathology. 176: 1705-15. PMID 20133817 DOI: 10.2353/Ajpath.2010.090451  0.35
2010 Lipskaia L, Chemaly ER, Hadri L, Lompre AM, Hajjar RJ. Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure. Expert Opinion On Biological Therapy. 10: 29-41. PMID 20078230 DOI: 10.1517/14712590903321462  0.364
2010 Jin H, Hadri L, Palomeque J, Morel C, Karakikes I, Kaprielian R, Hajjar R, Lebeche D. KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling. Journal of Molecular and Cellular Cardiology. 48: 1169-79. PMID 20051248 DOI: 10.1016/J.Yjmcc.2009.12.019  0.717
2010 Jin H, Chemaly ER, Lee A, Kho C, Hadri L, Hajjar RJ, Akar FG. Mechanoelectrical remodeling and arrhythmias during progression of hypertrophy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 451-63. PMID 19825979 DOI: 10.1096/fj.09-136622  0.32
2009 Cutler MJ, Wan X, Laurita KR, Hajjar RJ, Rosenbaum DS. Targeted SERCA2a gene expression identifies molecular mechanism and therapeutic target for arrhythmogenic cardiac alternans. Circulation. Arrhythmia and Electrophysiology. 2: 686-94. PMID 19948504 DOI: 10.1161/CIRCEP.109.863118  0.328
2009 Karakikes I, Kim M, Hadri L, Sakata S, Sun Y, Zhang W, Chemaly ER, Hajjar RJ, Lebeche D. Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. Plos One. 4: e6474. PMID 19649297 DOI: 10.1371/Journal.Pone.0006474  0.673
2009 Nicolaou P, Hajjar RJ, Kranias EG. Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. Journal of Molecular and Cellular Cardiology. 47: 365-71. PMID 19481088 DOI: 10.1016/J.Yjmcc.2009.05.010  0.374
2009 Nicolaou P, Rodriguez P, Ren X, Zhou X, Qian J, Sadayappan S, Mitton B, Pathak A, Robbins J, Hajjar RJ, Jones K, Kranias EG. Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury. Circulation Research. 104: 1012-20. PMID 19299645 DOI: 10.1161/Circresaha.108.189811  0.378
2009 Lee SH, Yang DK, Choi BY, Lee YH, Kim SY, Jeong D, Hajjar RJ, Park WJ. The transcription factor Eya2 prevents pressure overload-induced adverse cardiac remodeling. Journal of Molecular and Cellular Cardiology. 46: 596-605. PMID 19272299 DOI: 10.1016/j.yjmcc.2008.12.021  0.402
2009 Suckau L, Fechner H, Chemaly E, Krohn S, Hadri L, Kockskämper J, Westermann D, Bisping E, Ly H, Wang X, Kawase Y, Chen J, Liang L, Sipo I, Vetter R, ... ... Hajjar RJ, et al. Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation. 119: 1241-52. PMID 19237664 DOI: 10.1161/CIRCULATIONAHA.108.783852  0.683
2009 Haider N, Arbustini E, Gupta S, Liu H, Narula N, Hajjar R, Moorjani N, Westaby S, Semigran MJ, Dec GW, Chandrashekhar Y, Narula J. Concurrent upregulation of endogenous proapoptotic and antiapoptotic factors in failing human hearts. Nature Clinical Practice. Cardiovascular Medicine. 6: 250-61. PMID 19234503 DOI: 10.1038/Ncpcardio1452  0.349
2009 Takewa Y, Chemaly ER, Takaki M, Liang LF, Jin H, Karakikes I, Morel C, Taenaka Y, Tatsumi E, Hajjar RJ. Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1117-24. PMID 19201995 DOI: 10.1152/ajpheart.01120.2008  0.372
2008 Cha H, Kim JM, Oh JG, Jeong MH, Park CS, Park J, Jeong HJ, Park BK, Lee YH, Jeong D, Yang DK, Bernecker OY, Kim DH, Hajjar RJ, Park WJ. PICOT is a critical regulator of cardiac hypertrophy and cardiomyocyte contractility. Journal of Molecular and Cellular Cardiology. 45: 796-803. PMID 18929570 DOI: 10.1016/j.yjmcc.2008.09.124  0.365
2008 Lebeche D, Davidoff AJ, Hajjar RJ. Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy. Nature Clinical Practice. Cardiovascular Medicine. 5: 715-24. PMID 18813212 DOI: 10.1038/ncpcardio1347  0.655
2008 Refaat M, Chemaly E, Lebeche D, Gwathmey JK, Hajjar RJ. Ventricular arrhythmias after left ventricular assist device implantation. Pacing and Clinical Electrophysiology : Pace. 31: 1246-52. PMID 18811803 DOI: 10.1111/j.1540-8159.2008.01173.x  0.662
2008 Kawase Y, Hajjar RJ. The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases. Nature Clinical Practice. Cardiovascular Medicine. 5: 554-65. PMID 18665137 DOI: 10.1038/ncpcardio1301  0.357
2008 Kim M, Oh JK, Sakata S, Liang I, Park W, Hajjar RJ, Lebeche D. Role of resistin in cardiac contractility and hypertrophy. Journal of Molecular and Cellular Cardiology. 45: 270-80. PMID 18597775 DOI: 10.1016/j.yjmcc.2008.05.006  0.717
2008 Misra P, Lebeche D, Ly H, Schwarzkopf M, Diaz G, Hajjar RJ, Schecter AD, Frangioni JV. Quantitation of CXCR4 expression in myocardial infarction using 99mTc-labeled SDF-1alpha. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 963-9. PMID 18483105 DOI: 10.2967/Jnumed.107.050054  0.601
2008 Kawase Y, Ly HQ, Prunier F, Lebeche D, Shi Y, Jin H, Hadri L, Yoneyama R, Hoshino K, Takewa Y, Sakata S, Peluso R, Zsebo K, Gwathmey JK, Tardif JC, ... ... Hajjar RJ, et al. Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure. Journal of the American College of Cardiology. 51: 1112-9. PMID 18342232 DOI: 10.1016/J.Jacc.2007.12.014  0.693
2008 Jeong D, Kim JM, Cha H, Oh JG, Park J, Yun SH, Ju ES, Jeon ES, Hajjar RJ, Park WJ. PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling. Circulation Research. 102: 711-9. PMID 18258855 DOI: 10.1161/CIRCRESAHA.107.165985  0.345
2008 Beeri R, Yosefy C, Guerrero JL, Nesta F, Abedat S, Chaput M, del Monte F, Handschumacher MD, Stroud R, Sullivan S, Pugatsch T, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, et al. Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation. Journal of the American College of Cardiology. 51: 476-86. PMID 18222360 DOI: 10.1016/J.Jacc.2007.07.093  0.324
2007 Sakata S, Liang L, Sakata N, Sakata Y, Chemaly ER, Lebeche D, Takewa Y, Chen J, Park WJ, Kawase Y, Hajjar RJ. Preservation of mechanical and energetic function after adenoviral gene transfer in normal rat hearts. Clinical and Experimental Pharmacology & Physiology. 34: 1300-6. PMID 17973872 DOI: 10.1111/j.1440-1681.2007.04742.x  0.694
2007 Kühn B, del Monte F, Hajjar RJ, Chang YS, Lebeche D, Arab S, Keating MT. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nature Medicine. 13: 962-9. PMID 17632525 DOI: 10.1038/nm1619  0.679
2007 Kaye DM, Preovolos A, Marshall T, Byrne M, Hoshijima M, Hajjar R, Mariani JA, Pepe S, Chien KR, Power JM. Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals. Journal of the American College of Cardiology. 50: 253-60. PMID 17631218 DOI: 10.1016/J.Jacc.2007.03.047  0.383
2007 Yang DK, Choi BY, Lee YH, Kim YG, Cho MC, Hong SE, Kim DH, Hajjar RJ, Park WJ. Gene profiling during regression of pressure overload-induced cardiac hypertrophy. Physiological Genomics. 30: 1-7. PMID 17327491 DOI: 10.1152/physiolgenomics.00246.2006  0.386
2007 Sakata S, Lebeche D, Sakata N, Sakata Y, Chemaly ER, Liang LF, Tsuji T, Takewa Y, del Monte F, Peluso R, Zsebo K, Jeong D, Park WJ, Kawase Y, Hajjar RJ. Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins. Journal of Molecular and Cellular Cardiology. 42: 852-61. PMID 17300800 DOI: 10.1016/j.yjmcc.2007.01.003  0.63
2007 Sakata S, Lebeche D, Sakata N, Sakata Y, Chemaly ER, Liang LF, Takewa Y, Jeong D, Park WJ, Kawase Y, Hajjar RJ. Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2356-63. PMID 17220178 DOI: 10.1152/ajpheart.01310.2006  0.672
2007 Sakata S, Lebeche D, Sakata Y, Sakata N, Chemaly ER, Liang L, Nakajima-Takenaka C, Tsuji T, Konishi N, del Monte F, Hajjar RJ, Takaki M. Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1204-7. PMID 17012346 DOI: 10.1152/ajpheart.00892.2006  0.655
2006 Pyo RT, Sui J, Dhume A, Palomeque J, Blaxall BC, Diaz G, Tunstead J, Logothetis DE, Hajjar RJ, Schecter AD. CXCR4 modulates contractility in adult cardiac myocytes. Journal of Molecular and Cellular Cardiology. 41: 834-44. PMID 17010372 DOI: 10.1016/J.Yjmcc.2006.08.008  0.387
2006 Prunier F, Pfister O, Hadri L, Liang L, Del Monte F, Liao R, Hajjar RJ. Delayed erythropoietin therapy reduces post-MI cardiac remodeling only at a dose that mobilizes endothelial progenitor cells. American Journal of Physiology. Heart and Circulatory Physiology. 292: H522-9. PMID 16997893 DOI: 10.1152/ajpheart.00357.2006  0.301
2006 Jeong D, Cha H, Kim E, Kang M, Yang DK, Kim JM, Yoon PO, Oh JG, Bernecker OY, Sakata S, Le TT, Cui L, Lee YH, Kim do H, Woo SH, ... ... Hajjar RJ, et al. PICOT inhibits cardiac hypertrophy and enhances ventricular function and cardiomyocyte contractility. Circulation Research. 99: 307-14. PMID 16809552 DOI: 10.1161/01.Res.0000234780.06115.2C  0.446
2006 Gianni D, Chan J, Gwathmey JK, del Monte F, Hajjar RJ. SERCA2a in heart failure: role and therapeutic prospects. Journal of Bioenergetics and Biomembranes. 37: 375-80. PMID 16691468 DOI: 10.1007/s10863-005-9474-z  0.308
2006 Lebeche D, Kaprielian R, Hajjar R. Modulation of action potential duration on myocyte hypertrophic pathways. Journal of Molecular and Cellular Cardiology. 40: 725-35. PMID 16600293 DOI: 10.1016/J.Yjmcc.2006.01.018  0.671
2006 Sakata S, Lebeche D, Sakata Y, Sakata N, Chemaly ER, Liang LF, Padmanabhan P, Konishi N, Takaki M, del Monte F, Hajjar RJ. Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 987-96. PMID 16503203 DOI: 10.1016/j.ymthe.2006.01.002  0.676
2006 Hajjar RJ, Leopold JA. Xanthine oxidase inhibition and heart failure: novel therapeutic strategy for ventricular dysfunction? Circulation Research. 98: 169-71. PMID 16456108 DOI: 10.1161/01.RES.0000204557.09610.01  0.332
2006 Dally S, Bredoux R, Corvazier E, Andersen JP, Clausen JD, Dode L, Fanchaouy M, Gelebart P, Monceau V, Del Monte F, Gwathmey JK, Hajjar R, Chaabane C, Bobe R, Raies A, et al. Ca2+-ATPases in non-failing and failing heart: Evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c) Biochemical Journal. 395: 249-258. PMID 16402920 DOI: 10.1042/BJ20051427  0.331
2005 Lebeche D, Dalal R, Jang M, del Monte F, Hajjar RJ. Transgenic models of heart failure: elucidation of the molecular mechanisms of heart disease. Heart Failure Clinics. 1: 219-36. PMID 17386848 DOI: 10.1016/j.hfc.2005.03.005  0.659
2005 Schmidt U, Zhu X, Lebeche D, Huq F, Guerrero JL, Hajjar RJ. In vivo gene transfer of parvalbumin improves diastolic function in aged rat hearts. Cardiovascular Research. 66: 318-23. PMID 15820200 DOI: 10.1016/j.cardiores.2004.06.028  0.698
2005 Zhu X, Bernecker OY, Manohar NS, Hajjar RJ, Hellman J, Ichinose F, Valdivia HH, Schmidt U. Increased leakage of sarcoplasmic reticulum Ca2+ contributes to abnormal myocyte Ca2+ handling and shortening in sepsis Critical Care Medicine. 33: 598-604. PMID 15753753 DOI: 10.1097/01.CCM.0000152223.27176.A6  0.33
2005 Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, Mavila N, Jha L, Qian J, Marreez Y, Chen G, ... ... Hajjar RJ, et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circulation Research. 96: 756-66. PMID 15746443 DOI: 10.1161/01.Res.0000161256.85833.Fa  0.42
2005 Jain M, Pfister O, Hajjar RJ, Liao R. Mesenchymal stem cells in the infarcted heart. Coronary Artery Disease. 16: 93-7. PMID 15735401 DOI: 10.1097/00019501-200503000-00003  0.335
2005 del Monte F, Kizana E, Tabchy A, Hajjar RJ. Targeted gene transfer in heart failure: implications for novel gene identification. Current Opinion in Molecular Therapeutics. 6: 381-94. PMID 15468597  0.319
2004 Lebeche D, Kaprielian R, del Monte F, Tomaselli G, Gwathmey JK, Schwartz A, Hajjar RJ. In vivo cardiac gene transfer of Kv4.3 abrogates the hypertrophic response in rats after aortic stenosis. Circulation. 110: 3435-43. PMID 15557376 DOI: 10.1161/01.Cir.0000148176.33730.3F  0.682
2004 Boecker W, Bernecker OY, Wu JC, Zhu X, Sawa T, Grazette L, Rosenzweig A, del Monte F, Schmidt U, Hajjar RJ. Cardiac-specific gene expression facilitated by an enhanced myosin light chain promoter. Molecular Imaging. 3: 69-75. PMID 15296671 DOI: 10.1162/1535350041464847  0.334
2004 Del Monte F, Dalal R, Tabchy A, Couget J, Bloch KD, Peterson R, Hajjar RJ. Transcriptional changes following restoration of SERCA2a levels in failing rat hearts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1474-6. PMID 15247151 DOI: 10.1096/Fj.04-1714Fje  0.357
2004 Huq F, Lebeche D, Iyer V, Liao R, Hajjar RJ. Gene transfer of parvalbumin improves diastolic dysfunction in senescent myocytes. Circulation. 109: 2780-5. PMID 15173024 DOI: 10.1161/01.CIR.0000131764.62242.96  0.653
2004 Chaudhri BB, Del Monte F, Harding SE, Hajjar RJ. Gene transfer in cardiac myocytes Surgical Clinics of North America. 84: 141-159. PMID 15053187 DOI: 10.1016/S0039-6109(03)00209-3  0.303
2004 del Monte F, Lebeche D, Guerrero JL, Tsuji T, Doye AA, Gwathmey JK, Hajjar RJ. Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. Proceedings of the National Academy of Sciences of the United States of America. 101: 5622-7. PMID 15044708 DOI: 10.1073/pnas.0305778101  0.693
2004 Bernecker OY, del Monte F, Hajjar RJ. Gene therapy for the treatment of heart failure--calcium signaling. Seminars in Thoracic and Cardiovascular Surgery. 15: 268-76. PMID 12973704 DOI: 10.1016/s1043-0679(03)70006-9  0.349
2003 Bernecker OY, Huq F, Heist EK, Podesser BK, Hajjar RJ. Apoptosis in heart failure and the senescent heart. Cardiovascular Toxicology. 3: 183-90. PMID 14555785 DOI: 10.1385/CT:3:3:183  0.313
2003 Okafor CC, Perreault-Micale C, Hajjar RJ, Lebeche D, Skiroman K, Jabbour G, Doye AA, Lee MX, Laste N, Gwathmey JK. Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure Bmc Physiology [Electronic Resource]. 3: 6. PMID 12873352 DOI: 10.1186/1472-6793-3-1  0.667
2003 MacNeill BD, Hayase M, Hajjar RJ. Targeting signaling pathways in heart failure by gene transfer. Current Atherosclerosis Reports. 5: 178-85. PMID 12667429 DOI: 10.1007/s11883-003-0021-2  0.305
2003 Communal C, Huq F, Lebeche D, Mestel C, Gwathmey JK, Hajjar RJ. Decreased efficiency of adenovirus-mediated gene transfer in aging cardiomyocytes. Circulation. 107: 1170-5. PMID 12615797  0.607
2003 del Monte F, Hajjar RJ. Targeting calcium cycling proteins in heart failure through gene transfer. The Journal of Physiology. 546: 49-61. PMID 12509478 DOI: 10.1113/jphysiol.2002.026732  0.39
2003 Okafor CC, Saunders L, Li X, Ito T, Dixon M, Stepenek A, Hajjar RJ, Wood JR, Doye AA, Gwathmey JK. Myofibrillar responsiveness to cAMP, PKA, and caffeine in an animal model of heart failure. Biochemical and Biophysical Research Communications. 300: 592-9. PMID 12504124 DOI: 10.1016/S0006-291X(02)02885-1  0.309
2002 Huq F, Del Monte F, Hajjar RJ. Modulating signaling pathways in hypertrophy and heart failure by gene transfer. Journal of Cardiac Failure. 8: S389-400. PMID 12555151 DOI: 10.1054/jcaf.2002.129249  0.357
2002 Kaprielian R, del Monte F, Hajjar RJ. Targeting Ca2+ cycling proteins and the action potential in heart failure by gene transfer. Basic Research in Cardiology. 97: I136-45. PMID 12479247 DOI: 10.1007/S003950200042  0.338
2002 Neagoe C, Kulke M, del Monte F, Gwathmey JK, de Tombe PP, Hajjar RJ, Linke WA. Titin isoform switch in ischemic human heart disease. Circulation. 106: 1333-41. PMID 12221049 DOI: 10.1161/01.CIR.0000029803.93022.93  0.395
2002 Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, Breeden K, Jing SL, Allen PB, Greengard P, Yatani A, Hoit BD, Grupp IL, Hajjar RJ, DePaoli-Roach AA, et al. Type 1 phosphatase, a negative regulator of cardiac function. Molecular and Cellular Biology. 22: 4124-35. PMID 12024026 DOI: 10.1128/Mcb.22.12.4124-4135.2002  0.39
2002 Communal C, Sumandea M, de Tombe P, Narula J, Solaro RJ, Hajjar RJ. Functional consequences of caspase activation in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 99: 6252-6. PMID 11972044 DOI: 10.1073/Pnas.092022999  0.302
2002 Del Monte F, Butler K, Boecker W, Gwathmey JK, Hajjar RJ. Novel technique of aortic banding followed by gene transfer during hypertrophy and heart failure. Physiological Genomics. 9: 49-56. PMID 11948290 DOI: 10.1152/physiolgenomics.00035.2001  0.379
2002 del Monte F, Harding SE, Dec GW, Gwathmey JK, Hajjar RJ. Targeting phospholamban by gene transfer in human heart failure. Circulation. 105: 904-7. PMID 11864915 DOI: 10.1161/hc0802.105564  0.357
Low-probability matches (unlikely to be authored by this person)
2010 LaRocca TJ, Schwarzkopf M, Altman P, Zhang S, Gupta A, Gomes I, Alvin Z, Champion HC, Haddad G, Hajjar RJ, Devi LA, Schecter AD, Tarzami ST. β2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4. Journal of Cardiovascular Pharmacology. 56: 548-59. PMID 20729750 DOI: 10.1097/Fjc.0B013E3181F713Fe  0.3
2010 Beeri R, Chaput M, Guerrero JL, Kawase Y, Yosefy C, Abedat S, Karakikes I, Morel C, Tisosky A, Sullivan S, Handschumacher MD, Gilon D, Vlahakes GJ, Hajjar RJ, Levine RA. Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation. Circulation. Heart Failure. 3: 627-34. PMID 20634484 DOI: 10.1161/Circheartfailure.109.891184  0.299
2014 Cook JR, Carta L, Bénard L, Chemaly ER, Chiu E, Rao SK, Hampton TG, Yurchenco P, Costa KD, Hajjar RJ, Ramirez F. Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome. The Journal of Clinical Investigation. 124: 1329-39. PMID 24531548 DOI: 10.1172/Jci71059  0.298
2022 Fertig B, Ling J, Nollet EE, Dobi S, Busiau T, Ishikawa K, Yamada K, Lee A, Kho C, Wills L, Tibbo AJ, Scott M, Grant K, Campbell KS, Birks EJ, ... ... Hajjar R, et al. SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca. The Febs Journal. PMID 35633070 DOI: 10.1111/febs.16537  0.298
2014 Zsebo K, Yaroshinsky A, Rudy JJ, Wagner K, Greenberg B, Jessup M, Hajjar RJ. Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality. Circulation Research. 114: 101-8. PMID 24065463 DOI: 10.1161/CIRCRESAHA.113.302421  0.296
2003 del Monte F, Hajjar RJ. Efficient viral gene transfer to rodent hearts in vivo. Methods in Molecular Biology (Clifton, N.J.). 219: 179-93. PMID 12597008 DOI: 10.1385/1-59259-350-x:179  0.295
2015 Ishikawa K, Aguero J, Oh JG, Hammoudi N, A Fish L, Leonardson L, Picatoste B, Santos-Gallego CG, M Fish K, Hajjar RJ. Increased stiffness is the major early abnormality in a pig model of severe aortic stenosis and predisposes to congestive heart failure in the absence of systolic dysfunction. Journal of the American Heart Association. 4. PMID 25994443 DOI: 10.1161/JAHA.115.001925  0.295
2017 Chen J, Ceholski DK, Liang L, Fish K, Hajjar RJ. Variability in coronary artery anatomy affects consistency of cardiac damage following myocardial infarction in mice. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00127.2017. PMID 28550174 DOI: 10.1152/ajpheart.00127.2017  0.294
2013 Lipskaia L, Hadri L, Lopez JJ, Hajjar RJ, Bobe R. Benefit of SERCA2a gene transfer to vascular endothelial and smooth muscle cells: A new aspect in therapy of cardiovascular diseases Current Vascular Pharmacology. 11: 465-479. PMID 23905641 DOI: 10.2174/1570161111311040010  0.293
2003 Nakayama A, del Monte F, Hajjar RJ, Frangioni JV. Functional near-infrared fluorescence imaging for cardiac surgery and targeted gene therapy. Molecular Imaging. 1: 365-77. PMID 12940233 DOI: 10.1162/153535002321093972  0.293
2024 Magadum A, Sun J, Singh N, Kurian AA, Chepurko E, Fargnoli A, Hajjar R, Zhang J, Zangi L. Lin28a cardiomyocyte-specific modified mRNA translation system induces cardiomyocyte cell division and cardiac repair. Journal of Molecular and Cellular Cardiology. PMID 38301803 DOI: 10.1016/j.yjmcc.2024.01.007  0.293
2021 Haghighi K, Gardner G, Vafiadaki E, Kumar M, Green LC, Ma J, Crocker JS, Koch S, Arvanitis DA, Bidwell P, Rubinstein J, van de Leur R, Doevendans PA, Akar FG, Tranter M, ... ... Hajjar RJ, et al. Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias. Journal of Personalized Medicine. 11. PMID 34204946 DOI: 10.3390/jpm11060502  0.293
2022 Phillips KG, Turnbull IC, Hajjar RJ, Costa KD, Mayourian J. Cell Therapy Model Restores Failing Human Myocyte Electrophysiology and Calcium Cycling in Fibrotic Myocardium. Frontiers in Physiology. 12: 755881. PMID 35046835 DOI: 10.3389/fphys.2021.755881  0.293
2005 Sato M, Fuller SJ, Hajjar RJ, Harding SE. Targeting Genes and Cells in the Progression to Heart Failure Heart Failure Clinics. 1: 287-301. PMID 17386853 DOI: 10.1016/j.hfc.2005.04.001  0.292
2017 Kagan HJ, Belekdanian VD, Chen J, Backeris P, Hammoudi N, Turnbull IC, Costa KD, Hajjar RJ. Coronary Capillary Blood Flow in a Rat Model of Congestive Heart Failure. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00741.2017. PMID 29051335 DOI: 10.1152/Japplphysiol.00741.2017  0.291
2021 Raad N, Bittihn P, Cacheux M, Jeong D, Ilkan Z, Ceholski D, Kohlbrenner E, Zhang L, Cai CL, Kranias EG, Hajjar RJ, Stillitano F, Akar FG. Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Due to Phospholamban R14del Mutation. Circulation. PMID 34024116 DOI: 10.1161/CIRCULATIONAHA.119.043502  0.29
2010 Chaanine AH, Kalman J, Hajjar RJ. Cardiac Gene Therapy Seminars in Thoracic and Cardiovascular Surgery. 22: 127-139. PMID 21092890 DOI: 10.1053/j.semtcvs.2010.09.009  0.289
2021 Ramos-Kuri M, Meka SH, Salamanca-Buentello F, Hajjar RJ, Lipskaia L, Chemaly ER. Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies. Biological Research. 54: 23. PMID 34344467 DOI: 10.1186/s40659-021-00342-6  0.289
2008 Haddad GE, Saunders LJ, Crosby SD, Carles M, del Monte F, King K, Bristow MR, Spinale FG, Macgillivray TE, Semigran MJ, Dec GW, Williams SA, Hajjar RJ, Gwathmey JK. Human cardiac-specific cDNA array for idiopathic dilated cardiomyopathy: sex-related differences. Physiological Genomics. 33: 267-77. PMID 18303083 DOI: 10.1152/Physiolgenomics.00265.2007  0.287
2010 Lompré AM, Hajjar RJ, Harding SE, Kranias EG, Lohse MJ, Marks AR. Ca2+ cycling and new therapeutic approaches for heart failure. Circulation. 121: 822-30. PMID 20124124 DOI: 10.1161/Circulationaha.109.890954  0.286
2013 Gwathmey JK, Yerevanian A, Hajjar RJ. Targeting sarcoplasmic reticulum calcium ATPase by gene therapy. Human Gene Therapy. 24: 937-47. PMID 24164241 DOI: 10.1089/hum.2013.2512  0.286
2010 Lipskaia L, Ly H, Kawase Y, Hajjar RJ, Lompre AM. Treatment of heart failure by calcium cycling gene therapy. Future Cardiology. 3: 413-23. PMID 19804232 DOI: 10.2217/14796678.3.4.413  0.286
2015 Chen J, Yaniz-Galende E, Kagan HJ, Liang L, Hekmaty S, Giannarelli C, Hajjar R. Abnormalities of capillary microarchitecture in a rat model of coronary ischemic congestive heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 308: H830-40. PMID 25659485 DOI: 10.1152/ajpheart.00583.2014  0.285
2019 Katz MG, Fargnoli AS, Gubara SM, Chepurko E, Bridges CR, Hajjar RJ. Surgical and physiological challenges in the development of left and right heart failure in rat models. Heart Failure Reviews. PMID 30903356 DOI: 10.1007/S10741-019-09783-4  0.285
2008 Del Monte F, Hajjar RJ. Intracellular devastation in heart failure. Heart Failure Reviews. 13: 151-62. PMID 18347978 DOI: 10.1007/s10741-007-9071-9  0.284
2011 Ishikawa K, Tilemann L, Fish K, Hajjar RJ. Gene delivery methods in cardiac gene therapy Journal of Gene Medicine. 13: 566-572. PMID 21954037 DOI: 10.1002/jgm.1609  0.283
2003 Hajjar RJ, Huq F, Matsui T, Rosenzweig A. Genetic editing of dysfunctional myocardium. The Medical Clinics of North America. 87: 553-67. PMID 12693739 DOI: 10.1016/S0025-7125(02)00175-X  0.282
2011 Ishikawa K, Ladage D, Tilemann L, Kawase Y, Hajjar RJ. Sterile abscess in the myocardium after direct intramyocardial injection related to gene therapy in a Swine model. Isrn Cardiology. 2011: 319453. PMID 22347637 DOI: 10.5402/2011/319453  0.281
2019 Murphy JF, Mayourian J, Stillitano F, Munawar S, Broughton KM, Agullo-Pascual E, Sussman MA, Hajjar RJ, Costa KD, Turnbull IC. Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. Stem Cell Research & Therapy. 10: 373. PMID 31801634 DOI: 10.1186/S13287-019-1486-4  0.281
2005 Bukhari F, MacGillivray T, del Monte F, Hajjar RJ. Genetic maneuvers to ameliorate ventricular function in heart failure: therapeutic potential and future implications. Expert Review of Cardiovascular Therapy. 3: 85-97. PMID 15723577 DOI: 10.1586/14779072.3.1.85  0.281
2012 Lyon AR, Nikolaev VO, Miragoli M, Sikkel MB, Paur H, Benard L, Hulot JS, Kohlbrenner E, Hajjar RJ, Peters NS, Korchev YE, Macleod KT, Harding SE, Gorelik J. Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure. Circulation. Heart Failure. 5: 357-65. PMID 22456061 DOI: 10.1161/Circheartfailure.111.964692  0.281
2007 Albert CM, Nam EG, Rimm EB, Jin HW, Hajjar RJ, Hunter DJ, MacRae CA, Ellinor PT. Cardiac sodium channel gene variants and sudden cardiac death in women. Circulation. 117: 16-23. PMID 18071069 DOI: 10.1161/CIRCULATIONAHA.107.736330  0.28
2002 Chaudhri B, Del Monte F, Hajjar RJ, Harding SE. Interaction between increased SERCA2a activity and beta -adrenoceptor stimulation in adult rabbit myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 283: H2450-7. PMID 12388307 DOI: 10.1152/ajpheart.00391.2002  0.28
2007 Zhu X, Bagchi A, Zhao H, Kirschning CJ, Hajjar RJ, Chao W, Hellman J, Schmidt U. Toll-like receptor 2 activation by bacterial peptidoglycan-associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction Critical Care Medicine. 35: 886-892. PMID 17255871 DOI: 10.1097/01.CCM.0000256723.37586.A2  0.279
2009 Jaski BE, Jessup ML, Mancini DM, Cappola TP, Pauly DF, Greenberg B, Borow K, Dittrich H, Zsebo KM, Hajjar RJ. Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial. Journal of Cardiac Failure. 15: 171-81. PMID 19327618 DOI: 10.1016/j.cardfail.2009.01.013  0.279
2006 Antoun JG, Hajjar RJ. Gene and cell therapy in heart failure. Le Journal Medical Libanais. the Lebanese Medical Journal. 53: 28-38. PMID 16398210  0.279
2007 Ly H, Kawase Y, Yoneyama R, Hajjar RJ. Gene therapy in the treatment of heart failure. Physiology (Bethesda, Md.). 22: 81-96. PMID 17420300 DOI: 10.1152/physiol.00037.2006  0.278
2015 Gorski PA, Ceholski DK, Hajjar RJ. Altered myocardial calcium cycling and energetics in heart failure--a rational approach for disease treatment. Cell Metabolism. 21: 183-94. PMID 25651173 DOI: 10.1016/j.cmet.2015.01.005  0.278
2023 Li X, La Salvia S, Liang Y, Adamiak M, Kohlbrenner E, Jeong D, Chepurko E, Ceholski D, Lopez-Gordo E, Yoon S, Mathiyalagan P, Agarwal N, Jha D, Lodha S, Daaboul G, ... ... Hajjar RJ, et al. Extracellular Vesicle-Encapsulated AAVs for Therapeutic Gene Delivery to the Heart. Circulation. PMID 37409482 DOI: 10.1161/CIRCULATIONAHA.122.063759  0.277
2018 Chen J, Ceholski DK, Turnbull IC, Liang L, Hajjar RJ. Ischemic Model of Heart Failure in Rats and Mice. Methods in Molecular Biology (Clifton, N.J.). 1816: 175-182. PMID 29987819 DOI: 10.1007/978-1-4939-8597-5_13  0.277
2012 Ishikawa K, Chemaly ER, Tilemann L, Fish K, Ladage D, Aguero J, Vahl T, Santos-Gallego C, Kawase Y, Hajjar RJ. Assessing left ventricular systolic dysfunction after myocardial infarction: Are ejection fraction and dP/dt max complementary or redundant? American Journal of Physiology - Heart and Circulatory Physiology. 302. PMID 22307667 DOI: 10.1152/ajpheart.01211.2011  0.276
2019 Strauss B, Sassi Y, Bueno-Beti C, Ilkan Z, Raad N, Cacheux M, Bisserier M, Turnbull IC, Kohlbrenner E, Hajjar RJ, Hadri L, Akar FG. Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmonary arterial hypertension. Journal of Molecular and Cellular Cardiology. 127: 20-30. PMID 30502350 DOI: 10.1016/j.yjmcc.2018.11.017  0.273
2015 Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, ... ... Hajjar RJ, et al. Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. Nature Communications. 6: 6955. PMID 25923014 DOI: 10.1038/Ncomms7955  0.273
2019 Ishikawa K, Weber T, Hajjar RJ. Human Cardiac Gene Therapy. Circulation Research. 123: 601-613. PMID 30355138 DOI: 10.1161/CIRCRESAHA.118.311587  0.272
2014 Ishikawa K, Aguero J, Tilemann L, Ladage D, Hammoudi N, Kawase Y, Santos-Gallego CG, Fish K, Levine RA, Hajjar RJ. Characterizing preclinical models of ischemic heart failure: differences between LAD and LCx infarctions. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1478-86. PMID 25217654 DOI: 10.1152/Ajpheart.00797.2013  0.272
2016 Hulot JS, Ishikawa K, Hajjar RJ. Gene therapy for the treatment of heart failure: promise postponed. European Heart Journal. 37: 1651-8. PMID 26922809 DOI: 10.1093/eurheartj/ehw019  0.272
2021 Hajjar RJ, Leopold JA. Inflammation and Heart Failure: Friend or Foe? Circulation. 144: 1241-1243. PMID 34633863 DOI: 10.1161/CIRCULATIONAHA.121.056628  0.271
2017 Stillitano F, Hansen J, Kong CW, Karakikes I, Funck-Brentano C, Geng L, Scott S, Reynier S, Wu M, Valogne Y, Desseaux C, Salem JE, Jeziorowska D, Zahr N, Li R, ... ... Hajjar RJ, et al. Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells. Elife. 6. PMID 28134617 DOI: 10.7554/Elife.19406  0.271
2008 Ly HQ, Kawase Y, Hajjar RJ. Advances in gene-based therapy for heart failure. Journal of Cardiovascular Translational Research. 1: 127-36. PMID 20559907 DOI: 10.1007/s12265-008-9022-4  0.271
2009 Hajjar R, Fuster V. Cardiac cell and gene therapies: two trajectories, one goal. Nature Clinical Practice. Cardiovascular Medicine. 5: 749. PMID 19023329 DOI: 10.1038/ncpcardio1411  0.268
2017 Ceholski DK, Turnbull IC, Pothula V, Lecce L, Jarrah AA, Kho C, Lee A, Hadri L, Costa KD, Hajjar RJ, Tarzami ST. CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response. Stem Cell Research. 23: 77-86. PMID 28711757 DOI: 10.1016/J.Scr.2017.06.015  0.268
2012 Serrao GW, Turnbull IC, Ancukiewicz D, Kim do E, Kao E, Cashman TJ, Hadri L, Hajjar RJ, Costa KD. Myocyte-depleted engineered cardiac tissues support therapeutic potential of mesenchymal stem cells. Tissue Engineering. Part A. 18: 1322-33. PMID 22500611 DOI: 10.1089/Ten.Tea.2011.0278  0.268
2012 Oh JG, Jeong D, Cha H, Kim JM, Lifirsu E, Kim J, Yang DK, Park CS, Kho C, Park S, Yoo YJ, Kim DH, Kim J, Hajjar RJ, Park WJ. PICOT increases cardiac contractility by inhibiting PKCζ activity. Journal of Molecular and Cellular Cardiology. 53: 53-63. PMID 22449794 DOI: 10.1016/j.yjmcc.2012.03.005  0.268
2013 Hajjar RJ, Hulot JS. Myocardial delivery of stromal cell-derived factor 1 in patients with ischemic heart disease: safe and promising. Circulation Research. 112: 746-7. PMID 23429606 DOI: 10.1161/CIRCRESAHA.113.300902  0.267
2013 Ishikawa K, Aguero J, Naim C, Fish K, Hajjar RJ. Percutaneous approaches for efficient cardiac gene delivery. Journal of Cardiovascular Translational Research. 6: 649-59. PMID 23749638 DOI: 10.1007/s12265-013-9479-7  0.266
2018 Del Monte F, Ishikawa K, Hajjar RJ. Gene Transfer to Rodent Hearts In Vivo. Methods in Molecular Biology (Clifton, N.J.). 1521: 195-204. PMID 27910050 DOI: 10.1007/978-1-4939-6588-5_13  0.266
2010 Kho C, Lee A, Jeong D, Hajjar RJ. Refilling Intracellular Calcium Stores. Drug Discovery Today. Disease Mechanisms. 7: e145-e150. PMID 21170146 DOI: 10.1016/j.ddmec.2010.08.004  0.265
2016 Kim J, Kim J, Lee SH, Kepreotis SV, Yoo J, Chun JS, Hajjar RJ, Jeong D, Park WJ. Cytokine-Like 1 Regulates Cardiac Fibrosis via Modulation of TGF-β Signaling. Plos One. 11: e0166480. PMID 27835665 DOI: 10.1371/journal.pone.0166480  0.265
2016 Stillitano F, Turnbull IC, Karakikes I, Nonnenmacher M, Backeris P, Hulot JS, Kranias EG, Hajjar RJ, Costa KD. Genomic correction of familial cardiomyopathy in human engineered cardiac tissues. European Heart Journal. PMID 27450564 DOI: 10.1093/Eurheartj/Ehw307  0.263
2002 Huq F, Heist EK, Hajjar RJ. Titin--springing back to youth? Science of Aging Knowledge Environment : Sage Ke. 2002: pe20. PMID 14603021 DOI: 10.1126/sageke.2002.49.pe20  0.262
2016 Santos-Gallego CG, Vahl TP, Goliasch G, Picatoste B, Arias T, Ishikawa K, Njerve IU, Sanz J, Narula J, Sengupta PP, Hajjar RJ, Fuster V, Badimon JJ. Sphingosine-1-Phosphate Receptor Agonist Fingolimod Increases Myocardial Salvage and Decreases Adverse Postinfarction Left Ventricular Remodeling in a Porcine Model of Ischemia/Reperfusion. Circulation. 133: 954-66. PMID 26826180 DOI: 10.1161/CIRCULATIONAHA.115.012427  0.26
2005 Harding SE, del Monte F, Hajjar RJ. Antisense strategies for treatment of heart failure Methods in Molecular Medicine. 106: 69-82. PMID 15375313  0.26
2013 Oh JG, Kim J, Jang SP, Nguen M, Yang DK, Jeong D, Park ZY, Park SG, Hajjar RJ, Park WJ. Decoy peptides targeted to protein phosphatase 1 inhibit dephosphorylation of phospholamban in cardiomyocytes. Journal of Molecular and Cellular Cardiology. 56: 63-71. PMID 23262438 DOI: 10.1016/j.yjmcc.2012.12.005  0.26
2010 Hajjar RJ, Akar FG. Regression of cardiac hypertrophy by cyclic guanosine monophosphate-dependent protein kinase signaling are myocytes active sources or mere beneficiaries? Journal of the American College of Cardiology. 56: 2031-2. PMID 20970281 DOI: 10.1016/j.jacc.2010.09.005  0.259
2008 Haddad GE, Saunders L, Carles M, Crosby SD, del Monte F, Macgillivray TE, Semigran MJ, Dec GW, Hajjar RJ, Doye AA, Glass R, El M, Gwathmey JK. Fingerprint profile of alcohol-associated heart failure in human hearts. Alcoholism, Clinical and Experimental Research. 32: 814-21. PMID 18336640 DOI: 10.1111/j.1530-0277.2008.00628.x  0.259
2012 Yaniz-Galende E, Chen J, Chemaly E, Liang L, Hulot JS, McCollum L, Arias T, Fuster V, Zsebo KM, Hajjar RJ. Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells. Circulation Research. 111: 1434-45. PMID 22931954 DOI: 10.1161/CIRCRESAHA.111.263830  0.258
2018 Yoo J, Kohlbrenner E, Kim O, Hajjar RJ, Jeong D. Enhancing atrial specific gene expression using a calsequestrin cis-regulatory module 4 with a sarcolipin promoter. The Journal of Gene Medicine. e3060. PMID 30393908 DOI: 10.1002/jgm.3060  0.257
2013 Beaudoin J, Levine RA, Guerrero JL, Yosefy C, Sullivan S, Abedat S, Handschumacher MD, Szymanski C, Gilon D, Palmeri NO, Vlahakes GJ, Hajjar RJ, Beeri R. Late repair of ischemic mitral regurgitation does not prevent left ventricular remodeling: importance of timing for beneficial repair. Circulation. 128: S248-52. PMID 24030415 DOI: 10.1161/Circulationaha.112.000124  0.254
2018 Ceholski DK, Turnbull IC, Kong CW, Koplev S, Mayourian J, Gorski PA, Stillitano F, Skodras AA, Nonnenmacher M, Cohen N, Björkegren JLM, Stroik DR, Cornea RL, Thomas DD, Li RA, ... ... Hajjar RJ, et al. Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 29752948 DOI: 10.1016/J.Yjmcc.2018.05.007  0.253
2002 Beeri R, Guerrero JL, Supple G, Sullivan S, Levine RA, Hajjar RJ. New Efficient Catheter-Based System for Myocardial Gene Delivery Circulation. 106: 1756-1759. PMID 12356625 DOI: 10.1161/01.Cir.0000035240.92015.E4  0.252
2017 Chaanine AH, Sreekumaran Nair K, Bergen RH, Klaus K, Guenzel AJ, Hajjar RJ, Redfield MM. Mitochondrial Integrity and Function in the Progression of Early Pressure Overload-Induced Left Ventricular Remodeling. Journal of the American Heart Association. 6. PMID 28619984 DOI: 10.1161/Jaha.117.005869  0.252
2007 Iyer V, Hajjar RJ, Armoundas AA. Mechanisms of abnormal calcium homeostasis in mutations responsible for catecholaminergic polymorphic ventricular tachycardia. Circulation Research. 100: e22-31. PMID 17234962 DOI: 10.1161/01.RES.0000258468.31815.42  0.25
2008 Prunier F, Kawase Y, Gianni D, Scapin C, Danik SB, Ellinor PT, Hajjar RJ, Del Monte F. Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion. Circulation. 118: 614-24. PMID 18645052 DOI: 10.1161/CIRCULATIONAHA.108.770883  0.25
2003 Chaudhri B, del Monte F, Hajjar RJ, Harding SE. Contractile effects of adenovirally-mediated increases in SERCA2a activity: A comparison between adult rat and rabbit ventricular myocytes Molecular and Cellular Biochemistry. 251: 103-109. PMID 14575311 DOI: 10.1023/A:1025442201851  0.25
2012 Chemaly ER, Chaanine AH, Sakata S, Hajjar RJ. Stroke volume-to-wall stress ratio as a load-adjusted and stiffness-adjusted indicator of ventricular systolic performance in chronic loading. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 1267-84. PMID 22923502 DOI: 10.1152/japplphysiol.00785.2012  0.25
2005 Zhu X, Altschafl BA, Hajjar RJ, Valdivia HH, Schmidt U. Altered Ca2+ sparks and gating properties of ryanodine receptors in aging cardiomyocytes. Cell Calcium. 37: 583-91. PMID 15862349 DOI: 10.1016/j.ceca.2005.03.002  0.25
2013 Arias T, Chen J, Fayad ZA, Fuster V, Hajjar RJ, Chemaly ER. Comparison of echocardiographic measurements of left ventricular volumes to full volume magnetic resonance imaging in normal and diseased rats. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 26: 910-8. PMID 23706342 DOI: 10.1016/J.Echo.2013.04.016  0.249
2017 Stillitano F, Karakikes I, Hajjar RJ. Gene Transfer in Cardiomyocytes Derived from ES and iPS Cells. Methods in Molecular Biology (Clifton, N.J.). 1521: 183-193. PMID 27910049 DOI: 10.1007/978-1-4939-6588-5_12  0.248
2020 Wasala NB, Yue Y, Lostal W, Wasala LP, Niranjan N, Hajjar RJ, Babu GJ, Duan D. Single SERCA2a Therapy Ameliorated Dilated Cardiomyopathy for 18 Months in a Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31981493 DOI: 10.1016/J.Ymthe.2019.12.011  0.247
2017 Zangi L, Hajjar RJ. Synthetic MicroRNAs Stimulate Cardiac Repair. Circulation Research. 120: 1222-1223. PMID 28408445 DOI: 10.1161/CIRCRESAHA.117.310863  0.247
2007 Vila-Petroff M, Salas MA, Said M, Valverde CA, Sapia L, Portiansky E, Hajjar RJ, Kranias EG, Mundiña-Weilenmann C, Mattiazzi A. CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury. Cardiovascular Research. 73: 689-98. PMID 17217936 DOI: 10.1016/J.Cardiores.2006.12.003  0.246
2009 Tsuji T, Del Monte F, Yoshikawa Y, Abe T, Shimizu J, Nakajima-Takenaka C, Taniguchi S, Hajjar RJ, Takaki M. Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban. American Journal of Physiology. Heart and Circulatory Physiology. 296: H310-7. PMID 19074672 DOI: 10.1152/ajpheart.00975.2008  0.245
2014 Guzmán-Martínez G, Fernández-Friera L, Moral S, Shapiro S, Bates D, Hajjar R, García MJ, Fuster V, Sanz J. Intra-scar perfusion heterogeneity by cardiac magnetic resonance in a porcine model of non-reperfused myocardial infarction. International Journal of Cardiology. 176: 1288-9. PMID 25129306 DOI: 10.1016/j.ijcard.2014.07.179  0.244
2016 Bartunek J, Terzic A, Davison BA, Filippatos GS, Radovanovic S, Beleslin B, Merkely B, Musialek P, Wojakowski W, Andreka P, Horvath IG, Katz A, Dolatabadi D, El Nakadi B, Arandjelovic A, ... ... Hajjar RJ, et al. Cardiopoietic cell therapy for advanced ischemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial. European Heart Journal. PMID 28025189 DOI: 10.1093/Eurheartj/Ehw543  0.244
2017 Aguero J, Galan-Arriola C, Fernandez-Jimenez R, Sanchez-Gonzalez J, Ajmone N, Delgado V, Solis J, Lopez GJ, de Molina-Iracheta A, Hajjar RJ, Bax JJ, Fuster V, Ibáñez B. Atrial Infarction and Ischemic Mitral Regurgitation Contribute to Post-MI Remodeling of the Left Atrium. Journal of the American College of Cardiology. 70: 2878-2889. PMID 29216983 DOI: 10.1016/j.jacc.2017.10.013  0.243
2019 Chaanine AH, Hajjar RJ. Characterization of the Differential Progression of Left Ventricular Remodeling in a Rat Model of Pressure Overload Induced Heart Failure. Does Clip Size Matter? Methods in Molecular Biology (Clifton, N.J.). 1816: 195-206. PMID 29987821 DOI: 10.1007/978-1-4939-8597-5_15  0.242
2018 Ishikawa K, Watanabe S, Lee P, Akar FG, Lee A, Bikou O, Fish K, Kho C, Hajjar RJ. Acute Left Ventricular Unloading Reduces Atrial Stretch and Inhibits Atrial Arrhythmias. Journal of the American College of Cardiology. 72: 738-750. PMID 30092950 DOI: 10.1016/j.jacc.2018.05.059  0.242
2005 Palomeque J, Sapia L, Hajjar RJ, Mattiazzi A, Vila Petroff M. Angiotensin II-induced negative inotropy in rat ventricular myocytes: role of reactive oxygen species and p38 MAPK. American Journal of Physiology. Heart and Circulatory Physiology. 290: H96-106. PMID 16055523 DOI: 10.1152/ajpheart.00324.2005  0.24
2017 Kranias EG, Hajjar RJ. The Phospholamban Journey 4 Decades After Setting Out for Ithaka. Circulation Research. 120: 781-783. PMID 28254803 DOI: 10.1161/Circresaha.116.310007  0.24
2019 Bikou O, Ishikawa K, Fish KM, Zarragoikoetxea I, Hajjar RJ, Aguero J. Modeling Pulmonary Hypertension: A Pig Model of Postcapillary Pulmonary Hypertension. Methods in Molecular Biology (Clifton, N.J.). 1816: 367-383. PMID 29987835 DOI: 10.1007/978-1-4939-8597-5_29  0.238
2017 Voit A, Patel V, Pachon R, Shah V, Bakhutma M, Kohlbrenner E, McArdle JJ, Dell'Italia LJ, Mendell JR, Xie LH, Hajjar RJ, Duan D, Fraidenraich D, Babu GJ. Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice. Nature Communications. 8: 1068. PMID 29051551 DOI: 10.1038/S41467-017-01146-7  0.237
2009 Gwathmey JK, Tsaioun K, Hajjar RJ. Cardionomics: a new integrative approach for screening cardiotoxicity of drug candidates. Expert Opinion On Drug Metabolism & Toxicology. 5: 647-60. PMID 19442031 DOI: 10.1517/17425250902932915  0.236
2009 Ly HQ, Hoshino K, Pomerantseva I, Kawase Y, Yoneyama R, Takewa Y, Fortier A, Gibbs-Strauss SL, Vooght C, Frangioni JV, Hajjar RJ. In vivo myocardial distribution of multipotent progenitor cells following intracoronary delivery in a swine model of myocardial infarction. European Heart Journal. 30: 2861-8. PMID 19687154 DOI: 10.1093/Eurheartj/Ehp322  0.236
2002 Hajjar RJ, MacRae CA. Adrenergic-receptor polymorphisms and heart failure. The New England Journal of Medicine. 347: 1196-9. PMID 12374881 DOI: 10.1056/NEJME020105  0.235
2017 Ishikawa K, Watanabe S, Hammoudi N, Aguero J, Bikou O, Fish K, Hajjar RJ. Reduced Longitudinal Contraction is Associated with Ischemic Mitral Regurgitation after Posterior MI. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00546.2017. PMID 29101180 DOI: 10.1152/ajpheart.00546.2017  0.232
2016 Fargnoli AS, Katz MG, Bridges CR, Hajjar RJ. Gene Therapy in Heart Failure. Handbook of Experimental Pharmacology. PMID 27796512 DOI: 10.1007/164_2016_81  0.23
2019 Oh JG, Kho C, Hajjar RJ, Ishikawa K. Experimental models of cardiac physiology and pathology. Heart Failure Reviews. PMID 30666533 DOI: 10.1007/s10741-019-09769-2  0.23
2017 Watanabe S, Leonardson L, Hajjar RJ, Ishikawa K. Cardiac Gene Delivery in Large Animal Models: Antegrade Techniques. Methods in Molecular Biology (Clifton, N.J.). 1521: 227-235. PMID 27910053 DOI: 10.1007/978-1-4939-6588-5_16  0.23
2018 Ishikawa K, Hajjar RJ. Current Methods in Cardiac Gene Therapy: Overview. Methods in Molecular Biology (Clifton, N.J.). 1521: 3-14. PMID 27910038 DOI: 10.1007/978-1-4939-6588-5_1  0.23
2008 Lim CC, Yang H, Yang M, Wang CK, Shi J, Berg EA, Pimentel DR, Gwathmey JK, Hajjar RJ, Helmes M, Costello CE, Huo S, Liao R. A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility. Biophysical Journal. 94: 3577-89. PMID 18212018 DOI: 10.1529/Biophysj.107.112896  0.229
2020 Bartunek J, Terzic A, Davison BA, Behfar A, Sanz-Ruiz R, Wojakowski W, Sherman W, Heyndrickx GR, Metra M, Filippatos GS, Waldman SA, Teerlink JR, Henry TD, Gersh BJ, Hajjar R, et al. Cardiopoietic stem cell therapy in ischaemic heart failure: long-term clinical outcomes. Esc Heart Failure. PMID 33094909 DOI: 10.1002/ehf2.13031  0.228
2005 Lipskaia L, del Monte F, Capiod T, Yacoubi S, Hadri L, Hours M, Hajjar RJ, Lompré AM. Sarco/endoplasmic reticulum Ca2+-ATPase gene transfer reduces vascular smooth muscle cell proliferation and neointima formation in the rat. Circulation Research. 97: 488-95. PMID 16081870 DOI: 10.1161/01.RES.0000180663.42594.aa  0.226
2011 Kawase Y, Ladage D, Hajjar RJ. Method of gene delivery in large animal models of cardiovascular diseases. Methods in Molecular Biology (Clifton, N.J.). 709: 355-67. PMID 21194040 DOI: 10.1007/978-1-61737-982-6_23  0.226
2007 Beeri R, Yosefy C, Guerrero JL, Abedat S, Handschumacher MD, Stroud RE, Sullivan S, Chaput M, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA. Early repair of moderate ischemic mitral regurgitation reverses left ventricular remodeling: a functional and molecular study. Circulation. 116: I288-93. PMID 17846319 DOI: 10.1161/Circulationaha.106.681114  0.226
2019 Bisserier M, Milara J, Abdeldjebbar Y, Gubara S, Jones C, Bueno-Beti C, Chepurko E, Kohlbrenner E, Katz MG, Tarzami S, Cortijo J, Leopold J, Hajjar RJ, Sassi Y, Hadri L. AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31879190 DOI: 10.1016/J.Ymthe.2019.11.027  0.225
2003 Heist EK, Huq F, Hajjar R. Telomerase and the aging heart. Science of Aging Knowledge Environment : Sage Ke. 2003: PE11. PMID 12844532 DOI: 10.1126/Sageke.2003.19.Pe11  0.224
2018 Motloch LJ, Cacheux M, Ishikawa K, Xie C, Hu J, Aguero J, Fish KM, Hajjar RJ, Akar FG. Primary Effect of SERCA 2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction. Journal of the American Heart Association. 7: e009598. PMID 30371209 DOI: 10.1161/JAHA.118.009598  0.221
2011 Hulot JS, Fauconnier J, Ramanujam D, Chaanine A, Aubart F, Sassi Y, Merkle S, Cazorla O, Ouillé A, Dupuis M, Hadri L, Jeong D, Mühlstedt S, Schmitt J, Braun A, ... ... Hajjar RJ, et al. Critical role for stromal interaction molecule 1 in cardiac hypertrophy. Circulation. 124: 796-805. PMID 21810664 DOI: 10.1161/Circulationaha.111.031229  0.22
2003 Opitz CA, Kulke M, Leake MC, Neagoe C, Hinssen H, Hajjar RJ, Linke WA. Damped elastic recoil of the titin spring in myofibrils of human myocardium. Proceedings of the National Academy of Sciences of the United States of America. 100: 12688-93. PMID 14563922 DOI: 10.1073/pnas.2133733100  0.22
2019 Miyashita S, Hammoudi N, Watanabe S, Bikou O, Yamada K, Aguero J, Nomoto K, Kariya T, Fish K, Hajjar RJ, Ishikawa K. Echocardiographic Left Ventricular Mass Estimation: Two-Dimensional Area-Length Method is Superior to M-Mode Linear Method in Swine Models of Cardiac Diseases. Journal of Cardiovascular Translational Research. PMID 31828537 DOI: 10.1007/s12265-019-09937-7  0.219
2014 Pereda D, García-Alvarez A, Sánchez-Quintana D, Nuño M, Fernández-Friera L, Fernández-Jiménez R, García-Ruíz JM, Sandoval E, Aguero J, Castellá M, Hajjar RJ, Fuster V, Ibáñez B. Swine model of chronic postcapillary pulmonary hypertension with right ventricular remodeling: long-term characterization by cardiac catheterization, magnetic resonance, and pathology. Journal of Cardiovascular Translational Research. 7: 494-506. PMID 24771313 DOI: 10.1007/s12265-014-9564-6  0.219
2018 Stroik DR, Yuen SL, Janicek KA, Schaaf TM, Li J, Ceholski DK, Hajjar RJ, Cornea RL, Thomas DD. Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells. Scientific Reports. 8: 12560. PMID 30135432 DOI: 10.1038/S41598-018-29685-Z  0.217
2011 Ishikawa K, Ladage D, Takewa Y, Yaniz E, Chen J, Tilemann L, Sakata S, Badimon JJ, Hajjar RJ, Kawase Y. Development of a preclinical model of ischemic cardiomyopathy in swine. American Journal of Physiology. Heart and Circulatory Physiology. 301: H530-7. PMID 21551276 DOI: 10.1152/ajpheart.01103.2010  0.216
2017 Bonnet G, Ishikawa K, Hajjar RJ, Kawase Y. Direct Myocardial Injection of Vectors. Methods in Molecular Biology (Clifton, N.J.). 1521: 237-248. PMID 27910054 DOI: 10.1007/978-1-4939-6588-5_17  0.212
2018 Katz MG, Fargnoli AS, Hajjar RJ, Hadri L. Pulmonary hypertension arising from left heart disease causes intrapulmonary venous arterialization in rats. The Journal of Thoracic and Cardiovascular Surgery. 155: 281-282. PMID 29245197 DOI: 10.1016/J.Jtcvs.2017.08.028  0.21
2013 Ladage D, Yaniz-Galende E, Rapti K, Ishikawa K, Tilemann L, Shapiro S, Takewa Y, Muller-Ehmsen J, Schwarz M, Garcia MJ, Sanz J, Hajjar RJ, Kawase Y. Stimulating myocardial regeneration with periostin Peptide in large mammals improves function post-myocardial infarction but increases myocardial fibrosis. Plos One. 8: e59656. PMID 23700403 DOI: 10.1371/journal.pone.0059656  0.21
2017 Jeong D, Yoo J, Lee P, Kepreotis SV, Lee A, Wahlquist C, Brown BD, Kho C, Mercola M, Hajjar RJ. miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29273502 DOI: 10.1016/J.Ymthe.2017.11.014  0.209
2014 Karakikes I, Senyei GD, Hansen J, Kong CW, Azeloglu EU, Stillitano F, Lieu DK, Wang J, Ren L, Hulot JS, Iyengar R, Li RA, Hajjar RJ. Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes. Stem Cells Translational Medicine. 3: 18-31. PMID 24324277 DOI: 10.5966/Sctm.2013-0110  0.208
2019 Zaleta-Rivera K, Dainis A, Ribeiro AJS, Sanchez Cordero P, Rubio G, Shang C, Liu J, Finsterbach T, Parikh VN, Sutton S, Seo K, Sinha N, Jain N, Huang Y, Hajjar RJ, et al. Allele-Specific Silencing Ameliorates Restrictive Cardiomyopathy Due to a Human Myosin Regulatory Light Chain Mutation. Circulation. PMID 31315475 DOI: 10.1161/Circulationaha.118.036965  0.207
2008 Hajjar RJ, Zsebo K, Deckelbaum L, Thompson C, Rudy J, Yaroshinsky A, Ly H, Kawase Y, Wagner K, Borow K, Jaski B, London B, Greenberg B, Pauly DF, Patten R, et al. Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure. Journal of Cardiac Failure. 14: 355-67. PMID 18514926 DOI: 10.1016/j.cardfail.2008.02.005  0.206
2017 Poller W, Dimmeler S, Heymans S, Zeller T, Haas J, Karakas M, Leistner DM, Jakob P, Nakagawa S, Blankenberg S, Engelhardt S, Thum T, Weber C, Meder B, Hajjar R, et al. Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. European Heart Journal. PMID 28430919 DOI: 10.1093/Eurheartj/Ehx165  0.205
2014 Aguero J, Ishikawa K, Hadri L, Santos-Gallego C, Fish K, Hammoudi N, Chaanine A, Torquato S, Naim C, Ibanez B, Pereda D, García-Alvarez A, Fuster V, Sengupta PP, Leopold JA, ... Hajjar RJ, et al. Characterization of right ventricular remodeling and failure in a chronic pulmonary hypertension model. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1204-15. PMID 25158063 DOI: 10.1152/ajpheart.00246.2014  0.205
2008 Neilan TG, Ton-Nu TT, Kawase Y, Yoneyama R, Hoshino K, Del Monte F, Hajjar RJ, Picard MH, Levine RA, Hung J. Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes. American Journal of Physiology. Heart and Circulatory Physiology. 294: H2106-11. PMID 18326805 DOI: 10.1152/Ajpheart.01128.2007  0.203
2015 Lara-Pezzi E, Menasché P, Trouvin JH, Badimón L, Ioannidis JP, Wu JC, Hill JA, Koch WJ, De Felice AF, de Waele P, Steenwinckel V, Hajjar RJ, Zeiher AM. Guidelines for translational research in heart failure. Journal of Cardiovascular Translational Research. 8: 3-22. PMID 25604959 DOI: 10.1007/S12265-015-9606-8  0.203
2015 Das SK, Wang W, Zhabyeyev P, Basu R, McLean B, Fan D, Parajuli N, DesAulniers J, Patel VB, Hajjar RJ, Dyck JR, Kassiri Z, Oudit GY. Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy. Scientific Reports. 5: 18132. PMID 26638758 DOI: 10.1038/srep18132  0.203
2008 Ly HQ, Frangioni JV, Hajjar RJ. Imaging in cardiac cell-based therapy: in vivo tracking of the biological fate of therapeutic cells. Nature Clinical Practice. Cardiovascular Medicine. 5: S96-102. PMID 18641613 DOI: 10.1038/ncpcardio1159  0.203
2015 Chen G, Li S, Karakikes I, Ren L, Chow MZ, Chopra A, Keung W, Yan B, Chan CW, Costa KD, Kong CW, Hajjar RJ, Chen CS, Li RA. Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Circulation. Arrhythmia and Electrophysiology. 8: 193-202. PMID 25504561 DOI: 10.1161/Circep.114.002049  0.202
2014 Arias T, Petrov A, Chen J, de Haas H, Pérez-Medina C, Strijkers GJ, Hajjar RJ, Fayad ZA, Fuster V, Narula J. Labeling galectin-3 for the assessment of myocardial infarction in rats. Ejnmmi Research. 4: 75. PMID 26116131 DOI: 10.1186/S13550-014-0075-X  0.202
2007 Jneid H, Moukarbel GV, Dawson B, Hajjar RJ, Francis GS. Combining neuroendocrine inhibitors in heart failure: reflections on safety and efficacy. The American Journal of Medicine. 120: 1090.e1-8. PMID 18060931 DOI: 10.1016/j.amjmed.2007.02.029  0.2
2011 Bobe R, Hadri L, Lopez JJ, Sassi Y, Atassi F, Karakikes I, Liang L, Limon I, Lompré AM, Hatem SN, Hajjar RJ, Lipskaia L. SERCA2a controls the mode of agonist-induced intracellular Ca2+ signal, transcription factor NFAT and proliferation in human vascular smooth muscle cells Journal of Molecular and Cellular Cardiology. 50: 621-633. PMID 21195084 DOI: 10.1016/j.yjmcc.2010.12.016  0.199
2018 Mayourian J, Ceholski DK, Gorski P, Mathiyalagan P, Murphy JF, Salazar SI, Stillitano F, Hare JM, Sahoo S, Hajjar RJ, Costa KD. Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility. Circulation Research. PMID 29449318 DOI: 10.1161/Circresaha.118.312420  0.199
2002 Ranu HK, Terracciano CM, Davia K, Bernobich E, Chaudhri B, Robinson SE, Bin Kang Z, Hajjar RJ, MacLeod KT, Harding SE. Effects of Na(+)/Ca(2+)-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes. Journal of Molecular and Cellular Cardiology. 34: 389-400. PMID 11991729 DOI: 10.1006/Jmcc.2001.1521  0.196
2020 Bikou O, Hajjar RJ, Hadri L, Sassi Y. Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model. Journal of Visualized Experiments : Jove. PMID 32568218 DOI: 10.3791/59252  0.196
2014 Weng Z, Kong CW, Ren L, Karakikes I, Geng L, He J, Chow MZ, Mok CF, Keung W, Chow H, Leung AY, Hajjar RJ, Li RA, Chan CW. A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells. Stem Cells and Development. 23: 1704-16. PMID 24564569 DOI: 10.1089/scd.2013.0509  0.193
2016 Bartunek J, Davison B, Sherman W, Povsic T, Henry TD, Gersh B, Metra M, Filippatos G, Hajjar R, Behfar A, Homsy C, Cotter G, Wijns W, Tendera M, Terzic A. Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial design. European Journal of Heart Failure. 18: 160-8. PMID 26662998 DOI: 10.1002/Ejhf.434  0.192
2016 Jang SP, Oh JG, Kang DH, Kang JY, Kang SW, Hajjar RJ, Park WJ. A Decoy Peptide Targeted to Protein Phosphatase 1 Attenuates Degradation of SERCA2a in Vascular Smooth Muscle Cells. Plos One. 11: e0165569. PMID 27792751 DOI: 10.1371/journal.pone.0165569  0.189
2018 Hammoudi N, Watanabe S, Bikou O, Ceccaldi A, Fish K, Yamada KP, Miyashita S, Lebreton G, Hajjar RJ, Ishikawa K. Speckle-Tracking Echocardiographic Strain Analysis Reliably Estimates Degree of Acute LV Unloading During Mechanical LV Support by Impella. Journal of Cardiovascular Translational Research. PMID 29845440 DOI: 10.1007/s12265-018-9812-2  0.188
2013 Wang J, Chen A, Lieu DK, Karakikes I, Chen G, Keung W, Chan CW, Hajjar RJ, Costa KD, Khine M, Li RA. Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias. Biomaterials. 34: 8878-86. PMID 23942210 DOI: 10.1016/J.Biomaterials.2013.07.039  0.187
2013 Chen J, Petrov A, Yaniz-Galende E, Liang L, de Haas HJ, Narula J, Hajjar RJ. The impact of pressure overload on coronary vascular changes following myocardial infarction in rats. American Journal of Physiology. Heart and Circulatory Physiology. 304: H719-28. PMID 23275620 DOI: 10.1152/ajpheart.00793.2012  0.187
2017 Guénantin AC, Briand N, Capel E, Dumont F, Morichon R, Provost C, Stillitano F, Jeziorowska D, Siffroi JP, Hajjar RJ, Fève B, Hulot JS, Collas P, Capeau J, Vigouroux C. Functional Human Beige Adipocytes from Induced Pluripotent Stem Cells. Diabetes. PMID 28270520 DOI: 10.2337/Db16-1107  0.187
2011 Borah JC, Mujtaba S, Karakikes I, Zeng L, Muller M, Patel J, Moshkina N, Morohashi K, Zhang W, Gerona-Navarro G, Hajjar RJ, Zhou MM. A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chemistry & Biology. 18: 531-41. PMID 21513889 DOI: 10.1016/J.Chembiol.2010.12.021  0.186
2017 Watanabe S, Fish K, Bonnet G, Santos-Gallego CG, Leonardson L, Hajjar RJ, Ishikawa K. Echocardiographic and hemodynamic assessment for predicting early clinical events in severe acute mitral regurgitation. The International Journal of Cardiovascular Imaging. PMID 28735413 DOI: 10.1007/s10554-017-1215-y  0.185
2010 Poller W, Hajjar R, Schultheiss HP, Fechner H. Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure. Cardiovascular Research. 86: 353-64. PMID 20176815 DOI: 10.1093/cvr/cvq056  0.185
2012 Shimada YJ, Ishikawa K, Kawase Y, Ladage D, Tilemann L, Shiota T, Hajjar RJ. Comparison of left ventricular stroke volume assessment by two- and three-dimensional echocardiography in a swine model of acute myocardial infarction validated by thermodilution method. Echocardiography (Mount Kisco, N.Y.). 29: 1091-5. PMID 22672366 DOI: 10.1111/j.1540-8175.2012.01753.x  0.184
2013 Vandeput F, Szabo-Fresnais N, Ahmad F, Kho C, Lee A, Krall J, Dunlop A, Hazel MW, Wohlschlegel JA, Hajjar RJ, Houslay MD, Manganiello VC, Movsesian MA. Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms. Proceedings of the National Academy of Sciences of the United States of America. 110: 19778-83. PMID 24248367 DOI: 10.1073/Pnas.1305427110  0.183
2016 Oh JG, Hajjar RJ, Park WJ. Cardiac fibrosis and miR-433. Annals of Translational Medicine. 4: 511. PMID 28149873 DOI: 10.21037/atm.2016.11.28  0.181
2011 Fu JD, Rushing SN, Lieu DK, Chan CW, Kong CW, Geng L, Wilson KD, Chiamvimonvat N, Boheler KR, Wu JC, Keller G, Hajjar RJ, Li RA. Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes. Plos One. 6: e27417. PMID 22110643 DOI: 10.1371/Journal.Pone.0027417  0.178
2014 Hajjar RJ, Lyon AR. Gene therapy for the treatment of catecholaminergic polymorphic ventricular tachycardia. Circulation. 129: 2633-5. PMID 24958749 DOI: 10.1161/CIRCULATIONAHA.114.010586  0.177
2011 Chen J, Lee SK, Abd-Elgaliel WR, Liang L, Galende EY, Hajjar RJ, Tung CH. Assessment of cardiovascular fibrosis using novel fluorescent probes. Plos One. 6: e19097. PMID 21533060 DOI: 10.1371/journal.pone.0019097  0.176
2019 Li S, Chopra A, Keung W, Chan C, Costa KD, Kong CW, Hajjar RJ, Chen C, Li R. Sarco/Endoplasmic Reticulum Ca-ATPase is a more effective calcium remover than Sodium-Calcium Exchanger in human embryonic stem cell-derived cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31347915 DOI: 10.1152/Ajpheart.00540.2018  0.172
2016 Katz MG, Fargnoli AS, Kendle AP, Hajjar RJ, Bridges CR. Gene Therapy in Cardiac Surgery: Clinical Trials, Challenges, and Perspectives. The Annals of Thoracic Surgery. PMID 26801060 DOI: 10.1016/J.Athoracsur.2015.12.004  0.169
2014 Giannarelli C, Alique M, Rodriguez DT, Yang DK, Jeong D, Calcagno C, Hutter R, Millon A, Kovacic JC, Weber T, Faries PL, Soff GA, Fayad ZA, Hajjar RJ, Fuster V, et al. Alternatively spliced tissue factor promotes plaque angiogenesis through the activation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling. Circulation. 130: 1274-86. PMID 25116956 DOI: 10.1161/Circulationaha.114.006614  0.169
2018 Aguero J, Hadri L, Hammoudi N, Leonardson L, Hajjar RJ, Ishikawa K. Inhaled Gene Transfer for Pulmonary Circulation. Methods in Molecular Biology (Clifton, N.J.). 1521: 339-349. PMID 27910061 DOI: 10.1007/978-1-4939-6588-5_24  0.166
2006 Yoneyama R, Kawase Y, Hoshino K, McGregor J, Mac Neill BD, Lowe HC, Burkhoff D, Boekstegers P, Hajjar RJ, Hayase M. Magnetic resonance assessment of myocardial perfusion via catheter-based ventricle-coronary vein bypass in porcine myocardial infarction model. Catheterization and Cardiovascular Interventions : Official Journal of the Society For Cardiac Angiography & Interventions. 67: 58-67. PMID 16345049 DOI: 10.1002/ccd.20548  0.165
2011 Goonasekera SA, Lam CK, Millay DP, Sargent MA, Hajjar RJ, Kranias EG, Molkentin JD. Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. The Journal of Clinical Investigation. 121: 1044-52. PMID 21285509 DOI: 10.1172/Jci43844  0.162
2015 Rapti K, Stillitano F, Karakikes I, Nonnenmacher M, Weber T, Hulot JS, Hajjar RJ. Effectiveness of gene delivery systems for pluripotent and differentiated cells. Molecular Therapy. Methods & Clinical Development. 2: 14067. PMID 26052535 DOI: 10.1038/mtm.2014.67  0.161
2016 Aguero J, Ishikawa K, Hadri L, Santos-Gallego CG, Fish KM, Kohlbrenner E, Hammoudi N, Kho C, Lee A, Ibáñez B, García-Alvarez A, Zsebo K, Maron BA, Plataki M, Fuster V, ... ... Hajjar RJ, et al. Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension: A Large Animal Model. Journal of the American College of Cardiology. 67: 2032-46. PMID 27126531 DOI: 10.1016/j.jacc.2016.02.049  0.161
2005 Hayase M, Kawase Y, Yoneyama R, Hoshino K, McGregor J, MacNeill BD, Lowe HC, Burkhoff D, Boekstegers P, Hajjar RJ. Catheter-based ventricle-coronary vein bypass. Catheterization and Cardiovascular Interventions : Official Journal of the Society For Cardiac Angiography & Interventions. 65: 394-404. PMID 15822113 DOI: 10.1002/ccd.20312  0.159
2018 Bueno-Beti C, Sassi Y, Hajjar RJ, Hadri L. Pulmonary Artery Hypertension Model in Rats by Monocrotaline Administration. Methods in Molecular Biology (Clifton, N.J.). 1816: 233-241. PMID 29987824 DOI: 10.1007/978-1-4939-8597-5_18  0.158
2017 Mathiyalagan P, Liang Y, Kim D, Misener S, Thorne T, Kamide C, Klyachko E, Losordo DW, Hajjar RJ, Sahoo S. Angiogenic Mechanisms of Human CD34(+) Stem Cell Exosomes in the Repair of Ischemic Hindlimb. Circulation Research. PMID 28298297 DOI: 10.1161/CIRCRESAHA.116.310557  0.158
2019 Katz MG, Fargnoli AS, Gubara SM, Fish K, Weber T, Bridges CR, Hajjar RJ, Ishikawa K. Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer. Journal of Cardiovascular Development and Disease. 6. PMID 30781363 DOI: 10.3390/Jcdd6010008  0.152
2007 Hoshino K, Ly HQ, Frangioni JV, Hajjar RJ. In vivo tracking in cardiac stem cell-based therapy. Progress in Cardiovascular Diseases. 49: 414-20. PMID 17498521 DOI: 10.1016/j.pcad.2007.02.005  0.15
2014 Lipskaia L, Bobe R, Chen J, Turnbull IC, Lopez JJ, Merlet E, Jeong D, Karakikes I, Ross AS, Liang L, Mougenot N, Atassi F, Lompré AM, Tarzami ST, Kovacic JC, ... ... Hajjar RJ, et al. Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca2+ -ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells. Circulation. 129: 773-85. PMID 24249716 DOI: 10.1161/Circulationaha.113.002565  0.145
2011 Cimmino G, Giannarelli C, Chen W, Alique M, Santos-Gallego CG, Fuster V, Hajjar RJ, Walsh CE, Badimon JJ. Adeno-associated virus serotype 8 ApoA-I gene transfer reduces progression of atherosclerosis in ApoE-KO mice: comparison of intramuscular and intravenous administration. Journal of Cardiovascular Pharmacology. 57: 325-33. PMID 21164355 DOI: 10.1097/FJC.0b013e3182092841  0.145
2019 Katz MG, Fargnoli AS, Gubara SM, Bisserier M, Sassi Y, Bridges CR, Hajjar RJ, Hadri L. The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats. Journal of Visualized Experiments : Jove. PMID 30907889 DOI: 10.3791/59050  0.143
2004 Grazette LP, Boecker W, Matsui T, Semigran M, Force TL, Hajjar RJ, Rosenzweig A. Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy. Journal of the American College of Cardiology. 44: 2231-8. PMID 15582322 DOI: 10.1016/j.jacc.2004.08.066  0.142
2009 Cimmino G, Chen W, Speidl WS, Giannarelli C, Ibanez B, Fuster V, Hajjar R, Walsh CE, Badimon JJ. Safe and sustained overexpression of functional apolipoprotein A-I/high-density lipoprotein in apolipoprotein A-I-null mice by muscular adeno-associated viral serotype 8 vector gene transfer. Journal of Cardiovascular Pharmacology. 54: 405-11. PMID 19701094 DOI: 10.1097/FJC.0b013e3181bad264  0.141
2023 Ladak A, Hajjar RJ, Murali S, Michalek JJ, Riviere CN. Cable Tension Optimization for an Epicardial Parallel Wire Robot. Journal of Medical Devices. 17: 021006. PMID 37152412 DOI: 10.1115/1.4056866  0.141
2016 Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, ... ... Hajjar R, et al. Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability. Nature Communications. 7: 11853. PMID 27340017 DOI: 10.1038/ncomms11853  0.14
2019 Fish KM, Ishikawa K, Hajjar RJ. Stem cell therapy for acute myocardial infarction: on the horizon or still a dream? Coronary Artery Disease. 29: 89-91. PMID 29140809 DOI: 10.1097/MCA.0000000000000589  0.139
2018 Watanabe S, Ishikawa K, Plataki M, Bikou O, Kohlbrenner E, Aguero J, Hadri L, Zarragoikoetxea I, Fish K, Leopold JA, Hajjar RJ. Safety and long-term efficacy of AAV1.SERCA2a using nebulizer delivery in a pig model of pulmonary hypertension. Pulmonary Circulation. 8: 2045894018799738. PMID 30129881 DOI: 10.1177/2045894018799738  0.139
2014 Hulot JS, Stillitano F, Salem JE, Kovacic JC, Fuster V, Hajjar RJ. Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes. Stem Cell Research & Therapy. 5: 1. PMID 24405778 DOI: 10.1186/scrt390  0.133
2019 Katz MG, Fargnoli AS, Hajjar RJ, Jeong D. MicroRNA-25 upregulation protects spinal cords, yet is bad for the heart: The dark side of noncoding RNAS. The Journal of Thoracic and Cardiovascular Surgery. PMID 31003740 DOI: 10.1016/J.Jtcvs.2019.03.054  0.132
2010 Ishikawa K, Ladage D, Rapti K, Fernandez-Friera L, Maria Garcia-Lopez A, Sanz J, Hajjar RJ, Kawase Y, Garcia MJ. Multimodality imaging of chronic ischemia. Cardiology Research and Practice. 2011: 739702. PMID 20981290 DOI: 10.4061/2011/739702  0.131
2011 Chen A, Lieu DK, Freschauf L, Lew V, Sharma H, Wang J, Nguyen D, Karakikes I, Hajjar RJ, Gopinathan A, Botvinick E, Fowlkes CC, Li RA, Khine M. Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives. Advanced Materials (Deerfield Beach, Fla.). 23: 5785-91. PMID 22065428 DOI: 10.1002/Adma.201103463  0.13
2005 Hayase M, Del Monte F, Kawase Y, Macneill BD, McGregor J, Yoneyama R, Hoshino K, Tsuji T, De Grand AM, Gwathmey JK, Frangioni JV, Hajjar RJ. Catheter-based antegrade intracoronary viral gene delivery with coronary venous blockade. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2995-3000. PMID 15897329 DOI: 10.1152/ajpheart.00703.2004  0.13
2015 Hammoudi N, Ishikawa K, Hajjar RJ. Adeno-associated virus-mediated gene therapy in cardiovascular disease. Current Opinion in Cardiology. 30: 228-34. PMID 25783685 DOI: 10.1097/HCO.0000000000000159  0.13
2023 Poller W, Sahoo S, Hajjar R, Landmesser U, Krichevsky AM. Exploration of the Noncoding Genome for Human-Specific Therapeutic Targets-Recent Insights at Molecular and Cellular Level. Cells. 12. PMID 37998395 DOI: 10.3390/cells12222660  0.125
2018 Levine RA, Jerosch-Herold M, Hajjar RJ. Mitral Valve Prolapse: A Disease of Valve and Ventricle. Journal of the American College of Cardiology. 72: 835-837. PMID 30115221 DOI: 10.1016/J.Jacc.2018.07.006  0.125
2022 Bikou O, Tharakan S, Yamada K, Kariya T, Aguero J, Gordon A, Mazurek R, Aikawa T, Kohlbrenner E, Fish K, Hajjar RJ, Ishikawa K. Endo-bronchial aerosolized AAV1.SERCA2a gene therapy in a pulmonary hypertension pig model: addressing the lung delivery bottleneck. Human Gene Therapy. PMID 35293228 DOI: 10.1089/hum.2021.274  0.125
2019 Jones C, Bisserier M, Bueno-Beti C, Bonnet G, Neves-Zaph S, Lee SY, Milara J, Dorfmüller P, Humbert M, Leopold JA, Hadri L, Hajjar RJ, Sassi Y. A novel secreted-cAMP pathway inhibits pulmonary hypertension via a feed-forward mechanism. Cardiovascular Research. PMID 31529026 DOI: 10.1093/cvr/cvz244  0.125
2024 Kepreotis SV, Oh JG, Park M, Yoo J, Lee C, Mercola M, Hajjar RJ, Jeong D. Inhibition of miR-25 ameliorates cardiac and skeletal muscle dysfunction in aged haploinsufficient (+/-) mice. Molecular Therapy. Nucleic Acids. 35: 102174. PMID 38584818 DOI: 10.1016/j.omtn.2024.102174  0.12
2013 Louis Jeune V, Joergensen JA, Hajjar RJ, Weber T. Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy. Human Gene Therapy Methods. 24: 59-67. PMID 23442094 DOI: 10.1089/hgtb.2012.243  0.119
2011 Rapti K, Louis-Jeune V, Kohlbrenner E, Ishikawa K, Ladage D, Zolotukhin S, Hajjar RJ, Weber T. Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 73-83. PMID 21915102 DOI: 10.1038/mt.2011.177  0.119
2018 Katz MG, Fargnoli AS, Sassi Y, Hajjar RJ, Hadri L. Direct measurement of left atrial and pulmonary artery pressure in rats with pulmonary hypertension. The Journal of Thoracic and Cardiovascular Surgery. 156: 1161-1163. PMID 30119283 DOI: 10.1016/J.Jtcvs.2018.05.026  0.118
2015 Ishikawa K, Hajjar RJ. Revisiting Old Players in the Revitalized Field of Cardiovascular Gene Therapy. Journal of the American College of Cardiology. 66: 166-8. PMID 26160632 DOI: 10.1016/j.jacc.2015.04.065  0.118
2012 Ishikawa K, Kawase Y, Ladage D, Chemaly ER, Tilemann L, Fish K, Sanz J, Garcia MJ, Hajjar RJ. Temporal changes of strain parameters in the progress of chronic ischemia: With comparison to transmural infarction International Journal of Cardiovascular Imaging. 28: 1671-1681. PMID 22231467 DOI: 10.1007/s10554-012-0010-z  0.118
2018 Bueno-Beti C, Hadri L, Hajjar RJ, Sassi Y. The Sugen 5416/Hypoxia Mouse Model of Pulmonary Arterial Hypertension. Methods in Molecular Biology (Clifton, N.J.). 1816: 243-252. PMID 29987825 DOI: 10.1007/978-1-4939-8597-5_19  0.112
2010 Galende E, Karakikes I, Edelmann L, Desnick RJ, Kerenyi T, Khoueiry G, Lafferty J, McGinn JT, Brodman M, Fuster V, Hajjar RJ, Polgar K. Amniotic fluid cells are more efficiently reprogrammed to pluripotency than adult cells Cellular Reprogramming. 12: 117-125. PMID 20677926 DOI: 10.1089/Cell.2009.0077  0.106
2019 Aguero J, Hammoudi N, Bikou O, Fish KM, Zarragoikoetxea I, Hajjar RJ, Ishikawa K. Chronic Pulmonary Artery Embolization Models in Large Animals. Methods in Molecular Biology (Clifton, N.J.). 1816: 353-366. PMID 29987834 DOI: 10.1007/978-1-4939-8597-5_28  0.103
2017 Bansilal S, Vedanthan R, Kovacic JC, Soto AV, Latina J, Björkegren JLM, Jaslow R, Santana M, Sartori S, Giannarelli C, Mani V, Hajjar R, Schadt E, Kasarskis A, Fayad ZA, et al. Rationale and Design of Family-Based Approach in a Minority Community Integrating Systems-Biology for Promotion of Health (FAMILIA). American Heart Journal. 187: 170-181. PMID 28454800 DOI: 10.1016/J.Ahj.2017.02.020  0.103
2019 Fish KM, Hajjar RJ. Myocardial Cannabinoid Receptor Imaging in Obesity. Jacc. Cardiovascular Imaging. 11: 333-335. PMID 29413442 DOI: 10.1016/j.jcmg.2017.12.001  0.092
2013 Zhao S, Nishimura T, Chen Y, Azeloglu EU, Gottesman O, Giannarelli C, Zafar MU, Benard L, Badimon JJ, Hajjar RJ, Goldfarb J, Iyengar R. Systems pharmacology of adverse event mitigation by drug combinations. Science Translational Medicine. 5: 206ra140. PMID 24107779 DOI: 10.1126/Scitranslmed.3006548  0.091
2018 Michelis KC, Nomura-Kitabayashi A, Lecce L, Franzén O, Koplev S, Xu Y, Santini MP, D'Escamard V, Lee JTL, Fuster V, Hajjar R, Reddy RC, Chikwe J, Stelzer P, Filsoufi F, et al. CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries. Stem Cell Reports. 11: 242-257. PMID 30008326 DOI: 10.1016/j.stemcr.2018.06.001  0.087
2002 Kassiri Z, Hajjar R, Backx PH. Molecular components of transient outward potassium current in cultured neonatal rat ventricular myocytes. Journal of Molecular Medicine (Berlin, Germany). 80: 351-8. PMID 12072910 DOI: 10.1007/S00109-002-0325-7  0.087
2011 Turnbull IC, Hadri L, Rapti K, Sadek M, Liang L, Shin HJ, Costa KD, Marin ML, Hajjar RJ, Faries PL. Aortic implantation of mesenchymal stem cells after aneurysm injury in a porcine model. The Journal of Surgical Research. 170: e179-88. PMID 21764076 DOI: 10.1016/J.Jss.2011.05.042  0.085
2019 Katz MG, Fargnoli AS, Bridges CR, Hajjar RJ. Lentiviral-Mediated Interleukin-10 Gene Therapy for Lung Transplantation. The Journal of Thoracic and Cardiovascular Surgery. 157: 817-818. PMID 30669242 DOI: 10.1016/J.Jtcvs.2018.07.052  0.082
2012 Kohlbrenner E, Henckaerts E, Rapti K, Gordon RE, Linden RM, Hajjar RJ, Weber T. Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels. Human Gene Therapy Methods. 23: 198-203. PMID 22816378 DOI: 10.1089/Hgtb.2012.049  0.081
2013 Hadri L, Kratlian RG, Benard L, Maron BA, Dorfmüller P, Ladage D, Guignabert C, Ishikawa K, Aguero J, Ibanez B, Turnbull IC, Kohlbrenner E, Liang L, Zsebo K, Humbert M, ... ... Hajjar RJ, et al. Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension. Circulation. 128: 512-23. PMID 23804254 DOI: 10.1161/CIRCULATIONAHA.113.001585  0.079
2006 Chemaly ER, Yoneyama R, Frangioni JV, Hajjar RJ. Tracking stem cells in the cardiovascular system. Trends in Cardiovascular Medicine. 15: 297-302. PMID 16297767 DOI: 10.1016/j.tcm.2005.09.004  0.075
2017 Yoo J, Hajjar RJ, Jeong D. Generation of Efficient miRNA Inhibitors Using Tough Decoy Constructs. Methods in Molecular Biology (Clifton, N.J.). 1521: 41-53. PMID 27910040 DOI: 10.1007/978-1-4939-6588-5_3  0.072
2005 Frangioni JV, Hajjar RJ. In vivo tracking of stem cells for clinical trials in cardiovascular disease. Circulation. 110: 3378-83. PMID 15557385 DOI: 10.1161/01.CIR.0000149840.46523.FC  0.069
2015 Fish KM, Hajjar RJ. Mesenchymal Stem Cells & Endothelial Function. Ebiomedicine. 2: 376-7. PMID 26137582 DOI: 10.1016/j.ebiom.2015.04.015  0.069
2017 Sahoo S, Mathiyalagan P, Hajjar RJ. Pericardial Fluid Exosomes: A New Material to Treat Cardiovascular Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 568-569. PMID 28215995 DOI: 10.1016/j.ymthe.2017.02.002  0.067
2016 Vedanthan R, Bansilal S, Soto AV, Kovacic JC, Latina J, Jaslow R, Santana M, Gorga E, Kasarskis A, Hajjar R, Schadt EE, Björkegren JL, Fayad ZA, Fuster V. Family-Based Approaches to Cardiovascular Health Promotion. Journal of the American College of Cardiology. 67: 1725-37. PMID 27056780 DOI: 10.1016/J.Jacc.2016.01.036  0.06
2015 Aguero J, Ishikawa K, Fish KM, Hammoudi N, Hadri L, Garcia-Alvarez A, Ibanez B, Fuster V, Hajjar RJ, Leopold JA. Combination proximal pulmonary artery coiling and distal embolization induces chronic elevations in pulmonary artery pressure in Swine. Plos One. 10: e0124526. PMID 25923775 DOI: 10.1371/journal.pone.0124526  0.06
2018 Zimmermann WH, Yla-Herttuala S, Hajjar RJ. Highlighting the Field of Cardiovascular Regenerative Medicine. Molecular Therapy : the Journal of the American Society of Gene Therapy. 26: 1595. PMID 29934254 DOI: 10.1016/j.ymthe.2018.06.009  0.058
2007 Flaumenhaft R, Tanaka E, Graham GJ, De Grand AM, Laurence RG, Hoshino K, Hajjar RJ, Frangioni JV. Localization and quantification of platelet-rich thrombi in large blood vessels with near-infrared fluorescence imaging. Circulation. 115: 84-93. PMID 17179017 DOI: 10.1161/Circulationaha.106.643908  0.053
2014 Hajjar RJ, Hulot JS. Modeling CVD in human pluripotent cells by genome editing. Journal of the American College of Cardiology. 64: 460-2. PMID 25082578 DOI: 10.1016/j.jacc.2014.06.005  0.053
2007 Kawase Y, Suzuki Y, Ikeno F, Yoneyama R, Hoshino K, Ly HQ, Lau GT, Hayase M, Yeung AC, Hajjar RJ, Jang IK. Comparison of nonuniform rotational distortion between mechanical IVUS and OCT using a phantom model Ultrasound in Medicine and Biology. 33: 67-73. PMID 17189048 DOI: 10.1016/j.ultrasmedbio.2006.07.020  0.05
2021 Arze CA, Springer S, Dudas G, Patel S, Bhattacharyya A, Swaminathan H, Brugnara C, Delagrave S, Ong T, Kahvejian A, Echelard Y, Weinstein EG, Hajjar RJ, Andersen KG, Yozwiak NL. Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome. Cell Host & Microbe. PMID 34320399 DOI: 10.1016/j.chom.2021.07.001  0.049
2019 Fish KM, Mleczko J, Hajjar RJ. Of Mice and Men. Circulation Research. 123: 1109-1111. PMID 30359187 DOI: 10.1161/CIRCRESAHA.118.313990  0.046
2006 Kawase Y, Hoshino K, Yoneyama R, McGregor J, Hajjar RJ, Jang IK, Hayase M. In vivo volumetric analysis of coronary stent using optical coherence tomography with a novel balloon occlusion-flushing catheter: a comparison with intravascular ultrasound. Ultrasound in Medicine & Biology. 31: 1343-9. PMID 16223637 DOI: 10.1016/j.ultrasmedbio.2005.05.010  0.041
2017 Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, ... ... Hajjar R, et al. Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability. Nature Communications. 8: 14710. PMID 28205517 DOI: 10.1038/ncomms14710  0.041
2012 Hajjar RJ, Cormode DP. Tracking cell therapy: bioluminescence lighting the way. Jacc. Cardiovascular Imaging. 5: 56-8. PMID 22239893 DOI: 10.1016/j.jcmg.2011.09.017  0.04
2019 Hajjar RJ, Ishikawa K, Kovacic JC, Fuster V. Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai Translational Mission. Circulation Research. 121: 1316-1319. PMID 29217711 DOI: 10.1161/CIRCRESAHA.117.311372  0.04
2019 Fernandez-Jimenez R, Jaslow R, Bansilal S, Santana M, Diaz-Munoz R, Latina J, Soto AV, Vedanthan R, Al-Kazaz M, Giannarelli C, Kovacic JC, Bagiella E, Kasarskis A, Fayad ZA, Hajjar RJ, et al. Child Health Promotion in Underserved Communities: The FAMILIA Trial. Journal of the American College of Cardiology. 73: 2011-2021. PMID 31023422 DOI: 10.1016/J.Jacc.2019.01.057  0.038
2002 Hajjar RJ, Kradin RL. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-2002. A 55-year-old man with second-degree atrioventricular block and chest pain. The New England Journal of Medicine. 346: 1732-8. PMID 12037154 DOI: 10.1056/NEJMcpc020017  0.032
2018 Kranias EG, Doevendans PA, Glijnis PC, Hajjar RJ. PLN Foundation. Circulation Research. 123: 1276-1278. PMID 30566043 DOI: 10.1161/Circresaha.118.314014  0.026
2020 Magadum A, Kurian AA, Chepurko E, Sassi Y, Hajjar RJ, Zangi L. Specific Modified mRNA Translation System. Circulation. 142: 2485-2488. PMID 33347328 DOI: 10.1161/CIRCULATIONAHA.120.047211  0.025
2015 Nonnenmacher M, van Bakel H, Hajjar RJ, Weber T. High capsid-genome correlation facilitates creation of AAV libraries for directed evolution. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 675-82. PMID 25586687 DOI: 10.1038/mt.2015.3  0.024
2012 Hajjar RJ, Leri A, Wang Y. BCVS scientific conference 2012 meeting report. Circulation Research. 111: 1121-4. PMID 23065342 DOI: 10.1161/CIRCRESAHA.112.280966  0.022
2011 Hulot JS, Hajjar R, Montalescot G. Clopidogrel and CYP2C19 testing: ready for clinical prime time? Clinical Chemistry. 58: 154-7. PMID 21940658 DOI: 10.1373/clinchem.2011.165829  0.01
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