| Year |
Citation |
Score |
| 2018 |
Brunk E, Chang RL, Xia J, Hefzi H, Yurkovich JT, Kim D, Buckmiller E, Wang HH, Cho BK, Yang C, Palsson BO, Church GM, Lewis NE. Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301795 DOI: 10.1073/Pnas.1811971115 |
0.807 |
|
| 2018 |
McCloskey D, Xu S, Sandberg TE, Brunk E, Hefner Y, Szubin R, Feist AM, Palsson BO. Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism. Nature Communications. 9: 3796. PMID 30228271 DOI: 10.1038/S41467-018-06219-9 |
0.8 |
|
| 2018 |
McCloskey D, Xu S, Sandberg TE, Brunk E, Hefner Y, Szubin R, Feist AM, Palsson BO. Growth Adaptation of and Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome. Frontiers in Microbiology. 9: 1793. PMID 30131786 DOI: 10.3389/Fmicb.2018.01793 |
0.795 |
|
| 2018 |
McCloskey D, Xu S, Sandberg TE, Brunk E, Hefner Y, Szubin R, Feist AM, Palsson BO. Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in knockout evolutions. Applied and Environmental Microbiology. PMID 30054360 DOI: 10.1128/Aem.00823-18 |
0.795 |
|
| 2018 |
McCloskey D, Xu S, Sandberg TE, Brunk E, Hefner Y, Szubin R, Feist AM, Palsson BO. Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System. Metabolic Engineering. PMID 29906504 DOI: 10.1016/J.Ymben.2018.06.005 |
0.777 |
|
| 2018 |
McCloskey D, Xu S, Sandberg TE, Brunk E, Hefner Y, Szubin R, Feist AM, Palsson BO. Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes. Metabolic Engineering. PMID 29842925 DOI: 10.1016/J.Ymben.2018.05.012 |
0.8 |
|
| 2018 |
Brunk E, Sahoo S, Zielinski DC, Altunkaya A, Dräger A, Mih N, Gatto F, Nilsson A, Preciat Gonzalez GA, Aurich MK, Prlić A, Sastry A, Danielsdottir AD, Heinken A, Noronha A, et al. Recon3D enables a three-dimensional view of gene variation in human metabolism. Nature Biotechnology. PMID 29457794 DOI: 10.1038/Nbt.4072 |
0.78 |
|
| 2018 |
Mih N, Brunk E, Chen K, Catoiu E, Sastry A, Kavvas E, Monk JM, Zhang Z, Palsson BO, Valencia A. ssbio: A Python Framework for Structural Systems Biology. Bioinformatics (Oxford, England). PMID 29444205 DOI: 10.1093/Bioinformatics/Bty077 |
0.772 |
|
| 2017 |
Glusman G, Rose PW, Prlić A, Dougherty J, Duarte JM, Hoffman AS, Barton GJ, Bendixen E, Bergquist T, Bock C, Brunk E, Buljan M, Burley SK, Cai B, Carter H, et al. Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework. Genome Medicine. 9: 113. PMID 29254494 DOI: 10.1186/S13073-017-0509-Y |
0.315 |
|
| 2017 |
Monk JM, Lloyd CJ, Brunk E, Mih N, Sastry A, King Z, Takeuchi R, Nomura W, Zhang Z, Mori H, Feist AM, Palsson BO. iML1515, a knowledgebase that computes Escherichia coli traits. Nature Biotechnology. 35: 904-908. PMID 29020004 DOI: 10.1038/Nbt.3956 |
0.703 |
|
| 2017 |
Sastry A, Monk J, Tegel H, Uhlén M, Palsson BO, Rockberg J, Brunk E. Machine Learning in Computational Biology to Accelerate High-Throughput Protein Expression. Bioinformatics (Oxford, England). PMID 28398465 DOI: 10.1093/Bioinformatics/Btx207 |
0.762 |
|
| 2016 |
Ebrahim A, Brunk E, Tan J, O'Brien EJ, Kim D, Szubin R, Lerman JA, Lechner A, Sastry A, Bordbar A, Feist AM, Palsson BO. Multi-omic data integration enables discovery of hidden biological regularities. Nature Communications. 7: 13091. PMID 27782110 DOI: 10.1038/Ncomms13091 |
0.717 |
|
| 2016 |
Lechner A, Brunk E, Keasling JD. The Need for Integrated Approaches in Metabolic Engineering. Cold Spring Harbor Perspectives in Biology. PMID 27527588 DOI: 10.1101/Cshperspect.A023903 |
0.529 |
|
| 2016 |
Mih N, Brunk E, Bordbar A, Palsson BO. A Multi-scale Computational Platform to Mechanistically Assess the Effect of Genetic Variation on Drug Responses in Human Erythrocyte Metabolism. Plos Computational Biology. 12: e1005039. PMID 27467583 DOI: 10.1371/Journal.Pcbi.1005039 |
0.81 |
|
| 2016 |
Brunk E, George KW, Alonso-Gutierrez J, Thompson M, Baidoo E, Wang G, Petzold CJ, McCloskey D, Monk J, Yang L, O'Brien EJ, Batth TS, Martin HG, Feist A, Adams PD, et al. Characterizing Strain Variation in Engineered E. coli Using a Multi-Omics-Based Workflow. Cell Systems. PMID 27211860 DOI: 10.1016/J.Cels.2016.04.004 |
0.773 |
|
| 2016 |
Brunk E, Mih N, Monk J, Zhang Z, O'Brien EJ, Bliven SE, Chen K, Chang RL, Bourne PE, Palsson BO. Systems biology of the structural proteome. Bmc Systems Biology. 10: 26. PMID 26969117 DOI: 10.1186/S12918-016-0271-6 |
0.774 |
|
| 2015 |
Aziz RK, Khaw VL, Monk JM, Brunk E, Lewis R, Loh SI, Mishra A, Nagle AA, Satyanarayana C, Dhakshinamoorthy S, Luche M, Kitchen DB, Andrews KA, Palsson BØ, Charusanti P. Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC. Frontiers in Microbiology. 6: 958. PMID 26441892 DOI: 10.3389/Fmicb.2015.00958 |
0.702 |
|
| 2015 |
Guzmán GI, Utrilla J, Nurk S, Brunk E, Monk JM, Ebrahim A, Palsson BO, Feist AM. Model-driven discovery of underground metabolic functions in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 112: 929-34. PMID 25564669 DOI: 10.1073/Pnas.1414218112 |
0.807 |
|
| 2014 |
Latif H, Szubin R, Tan J, Brunk E, Lechner A, Zengler K, Palsson BO. A streamlined ribosome profiling protocol for the characterization of microorganisms. Biotechniques. 58: 329-32. PMID 26054770 DOI: 10.2144/000114302 |
0.77 |
|
| 2012 |
Brunk E, Neri M, Tavernelli I, Hatzimanikatis V, Rothlisberger U. Integrating computational methods to retrofit enzymes to synthetic pathways. Biotechnology and Bioengineering. 109: 572-82. PMID 21928337 DOI: 10.1002/Bit.23334 |
0.34 |
|
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