H. Frederik Nijhout - Publications

Affiliations: 
Biology Duke University, Durham, NC 
Website:
http://www.biology.duke.edu/nijhout/

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 He LL, Joo Shin SH, Wang Z, Yuan I, Weschler R, Chiou A, Koyama T, Nijhout HF, Suzuki Y. Mechanism of threshold size assessment: Metamorphosis is triggered by the TGF-beta/Activin ligand myoglianin. Insect Biochemistry and Molecular Biology. 103452. PMID 32822817 DOI: 10.1016/J.Ibmb.2020.103452  0.573
2020 Bhardwaj S, Jolander LS, Wenk MR, Oliver JC, Nijhout HF, Monteiro A. Origin of the mechanism of phenotypic plasticity in satyrid butterfly eyespots. Elife. 9. PMID 32041684 DOI: 10.7554/Elife.49544  0.355
2019 Nijhout HF. The multistep morphing of beetle horns. Science (New York, N.Y.). 366: 946-947. PMID 31753981 DOI: 10.1126/Science.Aaz9010  0.352
2019 Nijhout HF, McKenna KZ. Allometry, Scaling and Ontogeny of Form-An Introduction to the Symposium. Integrative and Comparative Biology. PMID 31553435 DOI: 10.1093/Icb/Icz143  0.379
2019 McKenna KZ, Tao D, Nijhout HF. Exploring the role of insulin signaling in relative growth: a case study on wing-body scaling in Lepidoptera. Integrative and Comparative Biology. PMID 31141129 DOI: 10.1093/Icb/Icz080  0.476
2018 Nijhout HF, Best JA, Reed MC. Systems biology of robustness and homeostatic mechanisms. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. e1440. PMID 30371009 DOI: 10.1002/Wsbm.1440  0.342
2018 Nijhout HF, McKenna KZ. Wing morphogenesis in Lepidoptera. Progress in Biophysics and Molecular Biology. PMID 29786506 DOI: 10.1016/J.Pbiomolbio.2018.04.008  0.394
2018 Nijhout HF, McKenna KZ. The distinct roles of insulin signaling in polyphenic development. Current Opinion in Insect Science. 25: 58-64. PMID 29602363 DOI: 10.1016/J.Cois.2017.11.011  0.357
2018 Nijhout HF, Laub E, Grunert LW. Hormonal control of growth in the wing imaginal disks of: the relative contributions of insulin and ecdysone. Development (Cambridge, England). PMID 29467243 DOI: 10.1242/Dev.160101  0.344
2017 Gawne R, McKenna KZ, Nijhout HF. Unmodern Synthesis: Developmental Hierarchies and the Origin of Phenotypes. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 29178269 DOI: 10.1002/Bies.201600265  0.322
2017 Nijhout HF, Sadre-Marandi F, Best J, Reed MC. Systems Biology of Phenotypic Robustness and Plasticity. Integrative and Comparative Biology. 57: 171-184. PMID 28859407 DOI: 10.1093/Icb/Icx076  0.341
2017 Nijhout HF, McKenna KZ. The Origin of Novelty Through the Evolution of Scaling Relationships. Integrative and Comparative Biology. PMID 28633448 DOI: 10.1093/Icb/Icx049  0.442
2016 Davidowitz G, Roff D, Nijhout HF. Synergism and Antagonism of Proximate Mechanisms Enable and Constrain the Response to Simultaneous Selection on Body Size and Development Time: An Empirical Test Using Experimental Evolution. The American Naturalist. 188: 499-520. PMID 27788344 DOI: 10.1086/688653  0.399
2015 Nijhout HF. Big or fast: two strategies in the developmental control of body size. Bmc Biology. 13: 57. PMID 26239356 DOI: 10.1186/S12915-015-0173-X  0.476
2015 Grunert LW, Clarke JW, Ahuja C, Eswaran H, Nijhout HF. A Quantitative Analysis of Growth and Size Regulation in Manduca sexta: The Physiological Basis of Variation in Size and Age at Metamorphosis. Plos One. 10: e0127988. PMID 26011714 DOI: 10.1371/Journal.Pone.0127988  0.495
2015 Xu HJ, Xue J, Lu B, Zhang XC, Zhuo JC, He SF, Ma XF, Jiang YQ, Fan HW, Xu JY, Ye YX, Pan PL, Li Q, Bao YY, Nijhout HF, et al. Two insulin receptors determine alternative wing morphs in planthoppers. Nature. 519: 464-7. PMID 25799997 DOI: 10.1038/Nature14286  0.361
2015 Nijhout HF, Callier V. Developmental mechanisms of body size and wing-body scaling in insects. Annual Review of Entomology. 60: 141-56. PMID 25341104 DOI: 10.1146/Annurev-Ento-010814-020841  0.768
2014 Callier V, Nijhout HF. Plasticity of insect body size in response to oxygen: integrating molecular and physiological mechanisms. Current Opinion in Insect Science. 1: 59-65. PMID 32846731 DOI: 10.1016/J.Cois.2014.05.007  0.73
2014 Nijhout HF, Best J, Reed MC. Escape from homeostasis. Mathematical Biosciences. 257: 104-10. PMID 25242608 DOI: 10.1016/J.Mbs.2014.08.015  0.329
2014 Nijhout HF, Riddiford LM, Mirth C, Shingleton AW, Suzuki Y, Callier V. The developmental control of size in insects. Wiley Interdisciplinary Reviews. Developmental Biology. 3: 113-34. PMID 24902837 DOI: 10.1002/Wdev.124  0.809
2014 Nijhout HF, Reed MC. Homeostasis and dynamic stability of the phenotype link robustness and plasticity. Integrative and Comparative Biology. 54: 264-75. PMID 24729131 DOI: 10.1093/Icb/Icu010  0.31
2014 Nijhout HF, Cinderella M, Grunert LW. The development of wing shape in Lepidoptera: mitotic density, not orientation, is the primary determinant of shape. Evolution & Development. 16: 68-77. PMID 24617986 DOI: 10.1111/Ede.12065  0.375
2013 Nijhout HF, Callier V. A new mathematical approach for qualitative modeling of the insulin-TOR-MAPK network. Frontiers in Physiology. 4: 245. PMID 24062690 DOI: 10.3389/Fphys.2013.00245  0.674
2013 Papa R, Kapan DD, Counterman BA, Maldonado K, Lindstrom DP, Reed RD, Nijhout HF, Hrbek T, McMillan WO. Multi-allelic major effect genes interact with minor effect QTLs to control adaptive color pattern variation in Heliconius erato. Plos One. 8: e57033. PMID 23533571 DOI: 10.1371/Journal.Pone.0057033  0.333
2013 Callier V, Nijhout HF. Body size determination in insects: a review and synthesis of size- and brain-dependent and independent mechanisms. Biological Reviews of the Cambridge Philosophical Society. 88: 944-54. PMID 23521745 DOI: 10.1111/Brv.12033  0.753
2013 Cho EH, Nijhout HF. Development of polyploidy of scale-building cells in the wings of Manduca sexta. Arthropod Structure & Development. 42: 37-46. PMID 23017249 DOI: 10.1016/J.Asd.2012.09.003  0.301
2012 Callier V, Nijhout HF. Supply-side constraints are insufficient to explain the ontogenetic scaling of metabolic rate in the tobacco Hornworm, Manduca sexta. Plos One. 7: e45455. PMID 23029018 DOI: 10.1371/Journal.Pone.0045455  0.689
2012 Davidowitz G, Nijhout HF, Roff DA. Predicting the response to simultaneous selection: genetic architecture and physiological constraints. Evolution; International Journal of Organic Evolution. 66: 2916-28. PMID 22946812 DOI: 10.1111/J.1558-5646.2012.01644.X  0.357
2012 Nijhout HF, German RZ. Developmental causes of allometry: new models and implications for phenotypic plasticity and evolution. Integrative and Comparative Biology. 52: 43-52. PMID 22634387 DOI: 10.1093/Icb/Ics068  0.418
2011 Callier V, Nijhout HF. Control of body size by oxygen supply reveals size-dependent and size-independent mechanisms of molting and metamorphosis. Proceedings of the National Academy of Sciences of the United States of America. 108: 14664-9. PMID 21873228 DOI: 10.1073/Pnas.1106556108  0.755
2011 Nijhout HF. Dependence of morphometric allometries on the growth kinetics of body parts. Journal of Theoretical Biology. 288: 35-43. PMID 21864540 DOI: 10.1016/J.Jtbi.2011.08.008  0.447
2011 Reed RD, Papa R, Martin A, Hines HM, Counterman BA, Pardo-Diaz C, Jiggins CD, Chamberlain NL, Kronforst MR, Chen R, Halder G, Nijhout HF, McMillan WO. optix drives the repeated convergent evolution of butterfly wing pattern mimicry. Science (New York, N.Y.). 333: 1137-41. PMID 21778360 DOI: 10.1126/Science.1208227  0.32
2011 Moczek AP, Sultan S, Foster S, Ledón-Rettig C, Dworkin I, Nijhout HF, Abouheif E, Pfennig DW. The role of developmental plasticity in evolutionary innovation. Proceedings. Biological Sciences / the Royal Society. 278: 2705-13. PMID 21676977 DOI: 10.1098/Rspb.2011.0971  0.573
2010 Nijhout HF, Grunert LW. The cellular and physiological mechanism of wing-body scaling in Manduca sexta. Science (New York, N.Y.). 330: 1693-5. PMID 21109634 DOI: 10.1126/Science.1197292  0.508
2010 Tobler A, Nijhout HF. Developmental constraints on the evolution of wing-body allometry in Manduca sexta. Evolution & Development. 12: 592-600. PMID 21040425 DOI: 10.1111/J.1525-142X.2010.00444.X  0.797
2010 Tobler A, Nijhout HF. A switch in the control of growth of the wing imaginal disks of Manduca sexta. Plos One. 5: e10723. PMID 20502707 DOI: 10.1371/Journal.Pone.0010723  0.775
2010 Nijhout HF, Roff DA, Davidowitz G. Conflicting processes in the evolution of body size and development time. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 567-75. PMID 20083633 DOI: 10.1098/Rstb.2009.0249  0.422
2010 Nijhout HF. Molecular and Physiological Basis of Colour Pattern Formation Advances in Insect Physiology. 38: 219-265. DOI: 10.1016/S0065-2806(10)38002-7  0.335
2009 Bowsher JH, Nijhout HF. Partial co-option of the appendage patterning pathway in the development of abdominal appendages in the sepsid fly Themira biloba. Development Genes and Evolution. 219: 577-87. PMID 20182886 DOI: 10.1007/S00427-010-0319-3  0.679
2008 Suzuki Y, Nijhout HF. Constraint and developmental dissociation of phenotypic integration in a genetically accommodated trait. Evolution & Development. 10: 690-9. PMID 19021739 DOI: 10.1111/J.1525-142X.2008.00282.X  0.574
2008 Nijhout HF. Size matters (but so does time), and it's OK to be different. Developmental Cell. 15: 491-2. PMID 18854132 DOI: 10.1016/J.Devcel.2008.09.014  0.446
2008 Suzuki Y, Nijhout HF. Genetic basis of adaptive evolution of a polyphenism by genetic accommodation. Journal of Evolutionary Biology. 21: 57-66. PMID 18034806 DOI: 10.1111/J.1420-9101.2007.01464.X  0.406
2008 Nijhout HF, Reed MC. A mathematical model for the regulation of juvenile hormone titers. Journal of Insect Physiology. 54: 255-64. PMID 18022634 DOI: 10.1016/J.Jinsphys.2007.09.008  0.305
2008 Nijhout HF, Suzuki Y. Environment and Genetic Accommodation Biological Theory. 3: 204-212. DOI: 10.1162/Biot.2008.3.3.204  0.482
2008 Nijhout HF. Developmental phenotypic landscapes Evolutionary Biology. 35: 100-103. DOI: 10.1007/S11692-008-9024-9  0.337
2007 Leduc D, Escartin F, Nijhout HF, Reed MC, Liebl U, Skouloubris S, Myllykallio H. Flavin-dependent thymidylate synthase ThyX activity: implications for the folate cycle in bacteria. Journal of Bacteriology. 189: 8537-45. PMID 17890305 DOI: 10.1128/Jb.01380-07  0.302
2007 Bowsher JH, Nijhout HF. Evolution of novel abdominal appendages in a sepsid fly from histoblasts, not imaginal discs. Evolution & Development. 9: 347-54. PMID 17651359 DOI: 10.1111/J.1525-142X.2007.00171.X  0.683
2007 Shingleton AW, Frankino WA, Flatt T, Nijhout HF, Emlen DJ. Size and shape: the developmental regulation of static allometry in insects. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 29: 536-48. PMID 17508394 DOI: 10.1002/Bies.20584  0.722
2007 Reed RD, Chen P, Nijhout HF. Cryptic variation in butterfly eyespot development: the importance of sample size in gene expression studies. Evolution & Development. 9: 2-9. PMID 17227362 DOI: 10.1111/J.1525-142X.2006.00133.X  0.366
2007 Nijhout HF, Smith WA, Schachar I, Subramanian S, Tobler A, Grunert LW. The control of growth and differentiation of the wing imaginal disks of Manduca sexta. Developmental Biology. 302: 569-76. PMID 17112498 DOI: 10.1016/J.Ydbio.2006.10.023  0.762
2006 Nijhout HF, Davidowitz G, Roff DA. A quantitative analysis of the mechanism that controls body size in Manduca sexta. Journal of Biology. 5: 16. PMID 16879739 DOI: 10.1186/Jbiol43  0.393
2006 Suzuki Y, Nijhout HF. Evolution of a polyphenism by genetic accommodation. Science (New York, N.Y.). 311: 650-2. PMID 16456077 DOI: 10.1126/Science.1118888  0.5
2004 Davidowitz G, Nijhout HF. The physiological basis of reaction norms: the interaction among growth rate, the duration of growth and body size. Integrative and Comparative Biology. 44: 443-9. PMID 21676730 DOI: 10.1093/Icb/44.6.443  0.46
2004 Yang AS, Martin CH, Nijhout HF. Geographic variation of caste structure among ant populations. Current Biology : Cb. 14: 514-9. PMID 15043818 DOI: 10.1016/J.Cub.2004.03.005  0.599
2004 Moczek AP, Nijhout HF. Trade-offs during the development of primary and secondary sexual traits in a horned beetle. The American Naturalist. 163: 184-91. PMID 14970921 DOI: 10.1086/381741  0.659
2003 Nijhout HF. Polymorphic mimicry in Papilio dardanus: mosaic dominance, big effects, and origins. Evolution & Development. 5: 579-92. PMID 14984040 DOI: 10.1046/J.1525-142X.2003.03063.X  0.307
2003 Nijhout HF. The control of growth. Development (Cambridge, England). 130: 5863-7. PMID 14597569 DOI: 10.1242/Dev.00902  0.41
2003 Nijhout HF. The control of body size in insects. Developmental Biology. 261: 1-9. PMID 12941617 DOI: 10.1016/S0012-1606(03)00276-8  0.357
2003 Moczek AP, Nijhout HF. Rapid evolution of a polyphenic threshold. Evolution & Development. 5: 259-68. PMID 12752765 DOI: 10.1046/J.1525-142X.2003.03033.X  0.635
2003 Davidowitz G, D'Amico LJ, Nijhout HF. Critical weight in the development of insect body size. Evolution & Development. 5: 188-97. PMID 12622736 DOI: 10.1046/J.1525-142X.2003.03026.X  0.793
2003 Nijhout HF. Development and evolution of adaptive polyphenisms. Evolution & Development. 5: 9-18. PMID 12492404 DOI: 10.1046/J.1525-142X.2003.03003.X  0.363
2003 Nijhout HF. The importance of context in genetics American Scientist. 91: 416-423. DOI: 10.1511/2003.32.885  0.323
2002 Nijhout HF, Grunert LW. Bombyxin is a growth factor for wing imaginal disks in Lepidoptera. Proceedings of the National Academy of Sciences of the United States of America. 99: 15446-50. PMID 12429853 DOI: 10.1073/Pnas.242548399  0.378
2002 Moczek AP, Nijhout HF. Developmental mechanisms of threshold evolution in a polyphenic beetle. Evolution & Development. 4: 252-64. PMID 12168618 DOI: 10.1046/J.1525-142X.2002.02014.X  0.675
2002 Moczek AP, Nijhout HF. A method for sexing final instar larvae of the genus Onthophagus Latreille (Coleoptera: Scarabaeidae) Coleopterists Bulletin. 56: 279-284. DOI: 10.1649/0010-065X(2002)056[0279:Amfsfi]2.0.Co;2  0.586
2001 Browder MH, D'Amico LJ, Nijhout HF. The role of low levels of juvenile hormone esterase in the metamorphosis of Manduca sexta. Journal of Insect Science (Online). 1: 11. PMID 15455071 DOI: 10.1673/031.001.1101  0.76
2001 D'Amico LJ, Davidowitz G, Nijhout HF. The developmental and physiological basis of body size evolution in an insect. Proceedings. Biological Sciences / the Royal Society. 268: 1589-93. PMID 11487406 DOI: 10.1098/Rspb.2001.1698  0.799
2001 Emlen DJ, Nijhout HF. Hormonal control of male horn length dimorphism in Onthophagus taurus (Coleoptera: Scarabaeidae): a second critical period of sensitivity to juvenile hormone. Journal of Insect Physiology. 47: 1045-1054. PMID 11472767 DOI: 10.1016/S0022-1910(01)00084-1  0.659
2001 Shafiei M, Moczek AP, Nijhout HF. Food availability controls the onset of metamorphosis in the dung beetle Onthophagus taurus (Coleoptera: Scarabaeidae) Physiological Entomology. 26: 173-180. DOI: 10.1046/J.1365-3032.2001.00231.X  0.589
2000 Miner AL, Rosenberg AJ, Nijhout HF. Control of growth and differentiation of the wing imaginal disk of Precis coenia (Lepidoptera: Nymphalidae). Journal of Insect Physiology. 46: 251-258. PMID 12770229 DOI: 10.1016/S0022-1910(99)00177-8  0.423
2000 Emlen DJ, Nijhout HF. The development and evolution of exaggerated morphologies in insects. Annual Review of Entomology. 45: 661-708. PMID 10761593 DOI: 10.1146/Annurev.Ento.45.1.661  0.632
1999 Klingenberg CP, Nijhout HF. GENETICS OF FLUCTUATING ASYMMETRY: A DEVELOPMENTAL MODEL OF DEVELOPMENTAL INSTABILITY. Evolution; International Journal of Organic Evolution. 53: 358-375. PMID 28565420 DOI: 10.1111/J.1558-5646.1999.Tb03772.X  0.559
1999 Emlen DJ, Nijhout HF. Hormonal control of male horn length dimorphism in the dung beetle Onthophagus taurus (Coleoptera: Scarabaeidae). Journal of Insect Physiology. 45: 45-53. PMID 12770395 DOI: 10.1016/S0022-1910(98)00096-1  0.617
1999 Weatherbee SD, Nijhout HF, Grunert LW, Halder G, Galant R, Selegue J, Carroll S. Ultrabithorax function in butterfly wings and the evolution of insect wing patterns. Current Biology : Cb. 9: 109-15. PMID 10021383 DOI: 10.1016/S0960-9822(99)80064-5  0.307
1999 Klingenberg CP, Nijhout HF. Genetics of fluctuating asymmetry: A developmental model of developmental instability Evolution. 53: 358-375.  0.505
1998 Nijhout HF, Kremen C. Control of pupal commitment in the imaginal disks of Precis coenia (Lepidoptera: Nymphalidae). Journal of Insect Physiology. 44: 287-296. PMID 12769963 DOI: 10.1016/S0022-1910(97)00121-2  0.604
1998 Nijhout HF, Emlen DJ. Competition among body parts in the development and evolution of insect morphology. Proceedings of the National Academy of Sciences of the United States of America. 95: 3685-9. PMID 9520426 DOI: 10.1073/Pnas.95.7.3685  0.706
1998 Klingenberg CP, Nijhout HF. Competition among growing organs and developmental control of morphological asymmetry Proceedings of the Royal Society B: Biological Sciences. 265: 1135-1139. DOI: 10.1098/Rspb.1998.0409  0.613
1997 Nijhout HF, Paulsen SM. Developmental models and polygenic characters American Naturalist. 149: 394-405. DOI: 10.1086/285996  0.355
1993 Paulsen SM, Nijhout HF. PHENOTYPIC CORRELATION STRUCTURE AMONG ELEMENTS OF THE COLOR PATTERN IN PRECIS COENIA (LEPIDOPTERA: NYMPHALIDAE). Evolution; International Journal of Organic Evolution. 47: 593-618. PMID 28568736 DOI: 10.1111/J.1558-5646.1993.Tb02115.X  0.346
1990 Nijhout HF, Wray GA, Gilbert LE. An analysis of the phenotypic effects of certain colour pattern genes in Heliconius (Lepidoptera: Nymphalidae) Biological Journal of the Linnean Society. 40: 357-372. DOI: 10.1111/J.1095-8312.1990.Tb00545.X  0.307
1989 Kremen C, Nijhout HF. Juvenile hormone controls the onset of pupal commitment in the imaginal disks and epidermis of Precis coenia (Lepidoptera: Nymphalidae) Journal of Insect Physiology. 35: 603-612. DOI: 10.1016/0022-1910(89)90122-4  0.563
1986 Nijhout HF. Pattern and Pattern Diversity on Lepidopteran Wings Bioscience. 36: 527-533. DOI: 10.2307/1310154  0.342
1985 Nijhout HF. The Developmental Physiology of Color Patterns in Lepidoptera Advances in Insect Physiology. 18: 181-247. DOI: 10.1016/S0065-2806(08)60041-7  0.309
1982 Nijhout HF, Wheeler DE. Juvenile hormone and the physiological basis of insect polymorphisms Quarterly Review of Biology. 57: 109-133. DOI: 10.1086/412671  0.341
1981 Wheeler DE, Nijhout HF. Soldier determination in ants: new role for juvenile hormone. Science (New York, N.Y.). 213: 361-3. PMID 17819911 DOI: 10.1126/Science.213.4505.361  0.353
1981 Nijhout HF. Physiological control of molting in insects Integrative and Comparative Biology. 21: 631-640. DOI: 10.1093/Icb/21.3.631  0.421
1981 Wheeler DE, Nijhout HF. Imaginal wing discs in larvae of the soldier caste of Pheidole bicarinata vinelandica Forel (Hymenoptera : Formicidae) International Journal of Insect Morphology and Embryology. 10: 131-139. DOI: 10.1016/S0020-7322(81)80018-9  0.35
1981 Smith WA, Nijhout HF. Effects of a juvenile hormone analogue on the duration of the fifth instar in the milkweed bug Oncopeltus fasciatus Journal of Insect Physiology. 27: 169-173. DOI: 10.1016/0022-1910(81)90124-4  0.311
1980 Nijhout HF. Ontogeny of the color pattern on the wings of Precis coenia (Lepidoptera: Nymphalidae). Developmental Biology. 80: 275-88. PMID 7192661 DOI: 10.1016/0012-1606(80)90404-2  0.306
1980 Nijhout HF. Pattern formation on lepidopteran wings: determination of an eyespot. Developmental Biology. 80: 267-74. PMID 7004953 DOI: 10.1016/0012-1606(80)90403-0  0.322
1979 Nijhout HF. Stretch-induced moulting in Oncopeltus fasciatus Journal of Insect Physiology. 25: 277-281. DOI: 10.1016/0022-1910(79)90055-6  0.379
1978 Nijhout HF, Carrow GM. Diuresis after a bloodmeal in female Anopheles freeborni Journal of Insect Physiology. 24: 293-298. DOI: 10.1016/0022-1910(78)90025-2  0.309
1978 Nijhout HF. Wing pattern formation in Lepidoptera: A model Journal of Experimental Zoology. 206: 119-136. DOI: 10.1002/Jez.1402060202  0.305
1975 Nijhout HF. Dynamics of juvenile hormone action in larvae of the tobacco hornworm, Manduca sexta (L.). The Biological Bulletin. 149: 568-79. PMID 1203337 DOI: 10.2307/1540387  0.31
1975 Nijhout HF. A threshold size for metamorphosis in the tobacco hornworm, Manduca sexta (L.). The Biological Bulletin. 149: 214-25. PMID 1138977 DOI: 10.2307/1540491  0.405
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