Amy J. Eshleman, Ph.D. - Publications

Affiliations: 
Psychiatry Oregon Health and Science University, Portland, OR 
Area:
neurotransmitter transporters, dopamine receptors, protein trafficking, therapeutics for drug and alcohol abuse, Parkinsons
Website:
http://www.ohsu.edu/xd/education/schools/school-of-medicine/academic-programs/graduate-studies/faculty/grad-studies-faculty.cfm?facultyid=96

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Torralva R, Eshleman AJ, Swanson TL, Schmachtenberg JL, Schutzer WE, Bloom SH, Wolfrum KM, Reed JF, Janowsky A. Fentanyl but not Morphine Interacts with Non-Opioid Recombinant Human Neurotransmitter Receptors and Transporters. The Journal of Pharmacology and Experimental Therapeutics. PMID 32513839 DOI: 10.1124/Jpet.120.265561  0.398
2019 Shi X, Swanson TL, Miner NB, Eshleman AJ, Janowsky A. Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2. Molecular Pharmacology. 96: 493-504. PMID 31409621 DOI: 10.1124/Mol.119.116798  0.339
2018 Eshleman AJ, Nagarajan S, Wolfrum KM, Reed JF, Swanson TL, Nilsen A, Janowsky A. Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters. Psychopharmacology. PMID 30397775 DOI: 10.1007/S00213-018-5059-5  0.305
2018 Eshleman AJ, Wolfrum KM, Reed JF, Kim SO, Johnson RA, Janowsky A. Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: high potency agonists at 5-HT receptors. Biochemical Pharmacology. PMID 30261175 DOI: 10.1016/J.Bcp.2018.09.024  0.409
2018 Provencher B, Eshleman AJ, Johnson RA, Shi X, Kryatova O, Nelson J, Tian J, Gonzalez M, Meltzer PC, Janowsky A. Synthesis and Discovery of Arylpiperidinylquinazolines: new inhibitors of the vesicular monoamine transporter. Journal of Medicinal Chemistry. PMID 30240563 DOI: 10.1021/Acs.Jmedchem.8B00542  0.455
2017 Tosh DK, Janowsky A, Eshleman AJ, Warnick E, Gao ZG, Chen Z, Gizewski E, Auchampach JA, Salvemini D, Jacobson KA. Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters. Journal of Medicinal Chemistry. PMID 28319392 DOI: 10.1021/Acs.Jmedchem.7B00141  0.476
2016 Eshleman AJ, Wolfrum KM, Reed JF, Kim SO, Swanson T, Johnson RA, Janowsky AJ. Structure-activity relationships of substituted cathinones, with transporter binding, uptake and release. The Journal of Pharmacology and Experimental Therapeutics. PMID 27799294 DOI: 10.1124/Jpet.116.236349  0.394
2016 Shi X, Walter NA, Harkness JH, Neve KA, Williams RW, Lu L, Belknap JK, Eshleman AJ, Phillips TJ, Janowsky A. Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function. Plos One. 11: e0152581. PMID 27031617 DOI: 10.1371/Journal.Pone.0152581  0.338
2016 Janowsky A, Tosh DK, Eshleman AJ, Jacobson KA. Rigid adenine nucleoside derivatives as novel modulators of the human sodium symporters for dopamine and other neurotransmitters. The Journal of Pharmacology and Experimental Therapeutics. PMID 26813929 DOI: 10.1124/Jpet.115.229666  0.459
2015 Carbonaro TM, Eshleman AJ, Forster MJ, Cheng K, Rice KC, Gatch MB. The role of 5-HT2A, 5-HT 2C and mGlu2 receptors in the behavioral effects of tryptamine hallucinogens N,N-dimethyltryptamine and N,N-diisopropyltryptamine in rats and mice. Psychopharmacology. 232: 275-84. PMID 24985890 DOI: 10.1007/S00213-014-3658-3  0.381
2014 Janowsky A, Eshleman AJ, Johnson RA, Wolfrum KM, Hinrichs DJ, Yang J, Zabriskie TM, Smilkstein MJ, Riscoe MK. Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro. Psychopharmacology. 231: 2771-83. PMID 24488404 DOI: 10.1007/S00213-014-3446-0  0.316
2014 Eshleman AJ, Forster MJ, Wolfrum KM, Johnson RA, Janowsky A, Gatch MB. Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function. Psychopharmacology. 231: 875-88. PMID 24142203 DOI: 10.1007/S00213-013-3303-6  0.304
2013 Eshleman AJ, Wolfrum KM, Hatfield MG, Johnson RA, Murphy KV, Janowsky A. Substituted methcathinones differ in transporter and receptor interactions. Biochemical Pharmacology. 85: 1803-15. PMID 23583454 DOI: 10.1016/J.Bcp.2013.04.004  0.541
2013 Holstein SE, Li N, Eshleman AJ, Phillips TJ. GABAB receptor activation attenuates the stimulant but not mesolimbic dopamine response to ethanol in FAST mice. Behavioural Brain Research. 237: 49-58. PMID 22982185 DOI: 10.1016/J.Bbr.2012.09.006  0.341
2012 Keith DJ, Wolfrum K, Eshleman AJ, Janowsky A. Melittin initiates dopamine transporter internalization and recycling in transfected HEK-293 cells. European Journal of Pharmacology. 690: 13-21. PMID 22683840 DOI: 10.1016/J.Ejphar.2012.05.020  0.431
2011 Gatch MB, Forster MJ, Janowsky A, Eshleman AJ. Abuse liability profile of three substituted tryptamines. The Journal of Pharmacology and Experimental Therapeutics. 338: 280-9. PMID 21474568 DOI: 10.1124/Jpet.111.179705  0.412
2011 Keith DJ, Eshleman AJ, Janowsky A. Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins. European Journal of Pharmacology. 650: 501-10. PMID 20969853 DOI: 10.1016/J.Ejphar.2010.10.023  0.454
2008 Wilhelm CJ, Johnson RA, Eshleman AJ, Janowsky A. Lobeline effects on tonic and methamphetamine-induced dopamine release. Biochemical Pharmacology. 75: 1411-5. PMID 18191815 DOI: 10.1016/J.Bcp.2007.11.019  0.454
2006 Bliziotes M, Eshleman A, Burt-Pichat B, Zhang XW, Hashimoto J, Wiren K, Chenu C. Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells Bone. 39: 1313-1321. PMID 16884969 DOI: 10.1016/J.Bone.2006.06.009  0.459
2006 Wilhelm CJ, Johnson RA, Eshleman AJ, Janowsky A. Hydrogen ion concentration differentiates effects of methamphetamine and dopamine on transporter-mediated efflux. Journal of Neurochemistry. 96: 1149-59. PMID 16417578 DOI: 10.1111/J.1471-4159.2005.03611.X  0.378
2005 Warden SJ, Bliziotes MM, Wiren KM, Eshleman AJ, Turner CH. Neural regulation of bone and the skeletal effects of serotonin (5-hydroxytryptamine). Molecular and Cellular Endocrinology. 242: 1-9. PMID 16085354 DOI: 10.1016/J.Mce.2005.06.005  0.305
2004 Wilhelm CJ, Johnson RA, Lysko PG, Eshleman AJ, Janowsky A. Effects of methamphetamine and lobeline on vesicular monoamine and dopamine transporter-mediated dopamine release in a cotransfected model system. The Journal of Pharmacology and Experimental Therapeutics. 310: 1142-51. PMID 15102929 DOI: 10.1124/Jpet.104.067314  0.434
2001 Janowsky A, Neve K, Eshleman AJ. Uptake and release of neurotransmitters. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit7.9. PMID 18428535 DOI: 10.1002/0471142301.Ns0709S02  0.442
2001 Bliziotes MM, Eshleman AJ, Zhang XW, Wiren KM. Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. Bone. 29: 477-86. PMID 11704501 DOI: 10.1016/S8756-3282(01)00593-2  0.424
2001 Eshleman AJ, Wolfrum K, Mash DC, Christensen K, Janowsky A. Drug interactions with the dopamine transporter in cryopreserved human caudate. The Journal of Pharmacology and Experimental Therapeutics. 296: 442-9. PMID 11160629  0.337
1999 Eshleman AJ, Carmolli M, Cumbay M, Martens CR, Neve KA, Janowsky A. Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type. The Journal of Pharmacology and Experimental Therapeutics. 289: 877-85. PMID 10215666  0.377
1998 Johnson RA, Eshleman AJ, Meyers T, Neve KA, Janowsky A. [3H]substrate- and cell-specific effects of uptake inhibitors on human dopamine and serotonin transporter-mediated efflux. Synapse (New York, N.Y.). 30: 97-106. PMID 9704886 DOI: 10.1002/(Sici)1098-2396(199809)30:1<97::Aid-Syn12>3.0.Co;2-M  0.484
1997 Eshleman AJ, Stewart E, Evenson AK, Mason JN, Blakely RD, Janowsky A, Neve KA. Metabolism of catecholamines by catechol-O-methyltransferase in cells expressing recombinant catecholamine transporters. Journal of Neurochemistry. 69: 1459-66. PMID 9326274 DOI: 10.1046/J.1471-4159.1997.69041459.X  0.45
1995 Eshleman AJ, Neve RL, Janowsky A, Neve KA. Characterization of a recombinant human dopamine transporter in multiple cell lines. The Journal of Pharmacology and Experimental Therapeutics. 274: 276-83. PMID 7616409  0.359
1994 Kline RH, Eshleman AJ, Wright J, Eldefrawi ME. Synthesis of substituted 3-carbamoylecgonine methyl ester analogues: irreversible and photoaffinity ligands for the cocaine receptor/dopamine transporter. Journal of Medicinal Chemistry. 37: 2249-52. PMID 8035432  0.319
1994 Eshleman AJ, Henningsen RA, Neve KA, Janowsky A. Release of dopamine via the human transporter. Molecular Pharmacology. 45: 312-6. PMID 7906856  0.399
1991 Kline RH, Wright J, Eshleman AJ, Fox KM, Eldefrawi ME. Synthesis of 3-carbamoylecgonine methyl ester analogues as inhibitors of cocaine binding and dopamine uptake. Journal of Medicinal Chemistry. 34: 702-5. PMID 1995895  0.301
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