Shu S. Chng, Ph.D.
Affiliations: | 2010 | Harvard University, Cambridge, MA, United States |
Area:
molecular mechanisms of various antibioticsGoogle:
"Shu Chng"Mean distance: 8.43 | S | N | B | C | P |
Parents
Sign in to add mentor| Daniel E. Kahne | grad student | 2010 | Harvard | |
| (Lipopolysaccharide assembly in Escherichia coli. Part A: Characterization of the function and biogenesis of the two-protein complex involved in LPS assembly at the outer membrane. Part B: Reconstitution of LPS transport across the periplasm via a trans-en) | ||||
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Publications
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| Rashid R, Nair ZJ, Chia DMH, et al. (2023) Depleting Cationic Lipids Involved in Antimicrobial Resistance Drives Adaptive Lipid Remodeling in Enterococcus faecalis. Mbio. e0307322 |
| Jiang X, Tan WB, Shrivastava R, et al. (2020) Mutations in enterobacterial common antigen biosynthesis restore outer membrane barrier function in Escherichia coli tol-pal mutants. Molecular Microbiology |
| Li M, Phua ZY, Xi Y, et al. (2020) Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition. Acs Infectious Diseases |
| Dupont C, Chen Y, Xu Z, et al. (2019) A piperidinol-containing molecule is active against by inhibiting the mycolic acid flippase activity of MmpL3. The Journal of Biological Chemistry |
| Shrivastava R, Chng S. (2019) Lipid trafficking across the Gram-negative cell envelope. Journal of Biological Chemistry. 294: 14175-14184 |
| Ercan B, Low WY, Liu X, et al. (2018) Characterization of interactions and phospholipid transfer between substrate binding proteins of the OmpC-Mla system. Biochemistry |
| Yeow J, Tan KW, Holdbrook DA, et al. (2018) The architecture of the OmpC-MlaA complex sheds light on the maintenance of outer membrane lipid asymmetry in . The Journal of Biological Chemistry |
| Isom GL, Davies NJ, Chong ZS, et al. (2017) MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis. Scientific Reports. 7: 8608 |
| Shrivastava R, Jiang X, Chng SS. (2017) Outer membrane lipid homeostasis via retrograde phospholipid transport in Escherichia coli. Molecular Microbiology |
| Xu Z, Meshcheryakov VA, Poce G, et al. (2017) MmpL3 is the flippase for mycolic acids in mycobacteria. Proceedings of the National Academy of Sciences of the United States of America |