Daniel E. Kahne

Affiliations:	1988-2004	Chemistry	Princeton University, Princeton, NJ
	2004-		Harvard University, Cambridge, MA, United States

Area:

molecular mechanisms of various antibiotics

Parents

Gilbert Stork	grad student	1986	Columbia
(Part I. Hydroxyl directed homogeneous hydrogenation using a catalytic iridium complex ; Part II. An approach to the synthesis of tetracycline)
W. Clark Still	post-doc	1988	Columbia

Children

Jeffrey Gildersleeve	grad student
Michael D Mandler	grad student		Harvard
Ran Xie	grad student
Dan Yang	grad student	1991	Princeton
Amy H. Andreotti	grad student	1994	Princeton
Kaustav Biswas	grad student	2000	Princeton
Hayley A. Xuereb	grad student	2000	Princeton
Zhong Chen	grad student	2001	Princeton
Ulrike S. Eggert	grad student	2001	Princeton
Kimberly M. Specht	grad student	2002	Princeton
Brian V. Falcone	grad student	2004	Princeton
John V. LaTour	grad student	2004	Princeton
Joonwoo Nam	grad student	2004	Princeton
Binyuan Sun	grad student	2004	Princeton
Christopher D. Brander	grad student	2005	Princeton
Catherine E. Leimkuhler	grad student	2006	Harvard
Scott A. McMurry	grad student	2006	Princeton
Hak S. Chung	grad student	2007	Harvard
Xuechen Li	grad student	2007	Harvard
Seokhee Kim	grad student	2008	Harvard
Wenjiang Zhu	grad student	2008	Harvard
Shu S. Chng	grad student	2010	Harvard
Michael B. Lazarus	grad student	2010	Harvard
Emma H. Doud	grad student	2011	Harvard
Tania J. Lupoli	grad student	2011	Harvard
Tsung-Shing Wang	grad student	2011	Harvard
Craig Braun	grad student	2012	Harvard
Elizaveta Freinkman	grad student	2012	Harvard
Christine L. Hagan	grad student	2012	Harvard
Yihui Wu	grad student	2012	Harvard
Zhizhong Yao	grad student	2012	Harvard
John Janetzko	grad student	2012-2017	Harvard
Frederick A Rubino	grad student	2012-2019	Harvard
Matthew J. Nava	post-doc
Matthew D. Lebar	post-doc	2011-	Harvard
Alessio Caruso	post-doc	2021-	Harvard (Neurotree)
Amit Basu	post-doc	1996-1999	Princeton

Collaborators

Suzanne Walker

collaborator

BETA: Related publications

Publications

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Park Y, Taguchi A, Baidin V, et al. (2023) A Time-Resolved FRET Assay Identifies a Small Molecule that Inhibits the Essential Bacterial Cell Wall Polymerase FtsW. Angewandte Chemie (International Ed. in English). e202301522
Kumar S, Mollo A, Rubino FA, et al. (2023) Chloride Ions Are Required for Thermosipho africanus MurJ Function. Mbio. e0008923
Kumar S, Mollo A, Kahne D, et al. (2022) The Bacterial Cell Wall: From Lipid II Flipping to Polymerization. Chemical Reviews
Melnyk S, Stepanyshyn A, Yushchuk O, et al. (2022) Genetic approaches to improve clorobiocin production in Streptomyces roseochromogenes NRRL 3504. Applied Microbiology and Biotechnology
Baidin V, Owens TW, Lazarus MB, et al. (2021) Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase. Journal of the American Chemical Society
Schaefer K, Owens TW, Page JE, et al. (2020) Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization. Nature Microbiology
Lundstedt E, Kahne D, Ruiz N. (2020) Assembly and Maintenance of Lipids at the Bacterial Outer Membrane. Chemical Reviews
Tomasek D, Rawson S, Lee J, et al. (2020) Structure of a nascent membrane protein as it folds on the BAM complex. Nature
Sjodt M, Rohs PDA, Gilman MSA, et al. (2020) Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nature Microbiology
Rubino FA, Mollo A, Kumar S, et al. (2020) Detection of transport intermediates in the peptidoglycan flippase MurJ identifies residues essential for conformational cycling. Journal of the American Chemical Society

Daniel E. Kahne

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Mean distance: 7.2

Parents

Children

Collaborators

Publications