Chris Williamson

Affiliations: 
Institute of Cancer Research, London, UK 
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Yap TA, O'Carrigan B, Penney MS, et al. (2020) Phase I Trial of First-in-Class ATR Inhibitor M6620 (VX-970) as Monotherapy or in Combination With Carboplatin in Patients With Advanced Solid Tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1902404
Holme H, Gulati A, Brough R, et al. (2018) Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness. Scientific Reports. 8: 10614
Fleuren ED, Jones S, Frankum J, et al. (2018) Abstract 2975: Synthetic lethality in synovial sarcoma: SS18-SSX fusions and DNA damage response (DDR) inhibitors Cancer Research. 78: 2975-2975
Brandsma I, Williamson C, Lord C. (2016) Exploiting synthetic lethal interactions in DNA repair deficient tumour cells using ATR inhibition European Journal of Cancer. 69: S120
Mateo J, Carreira S, Sandhu S, et al. (2015) DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer. The New England Journal of Medicine. 373: 1697-1708
Williamson CT, Kubota E, Hamill JD, et al. (2012) Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53. Embo Molecular Medicine. 4: 515-27
Williamson CT, Muzik H, Turhan AG, et al. (2010) ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors. Molecular Cancer Therapeutics. 9: 347-57
Williamson LM, Williamson CT, Lees-Miller SP. (2009) DNA Double strand break repair: Mechanisms and therapeutic potential The Dna Damage Response: Implications On Cancer Formation and Treatment. 157-177
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