TFC Mackay - Publications

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176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lyman RF, Lyman RA, Yamamoto A, Huang W, Harbison ST, Zhou S, Anholt RRH, Mackay TFC. Natural genetic variation in a dopamine receptor is associated with variation in female fertility in . Proceedings. Biological Sciences. 290: 20230375. PMID 37040806 DOI: 10.1098/rspb.2023.0375  0.443
2023 Anholt RRH, Mackay TFC. The genetic architecture of behavioral canalization. Trends in Genetics : Tig. PMID 36878820 DOI: 10.1016/j.tig.2023.02.007  0.342
2022 Mackay TFC, Anholt RRH. Gregor Mendel's legacy in quantitative genetics. Plos Biology. 20: e3001692. PMID 35852997 DOI: 10.1371/journal.pbio.3001692  0.312
2021 Özsoy ED, Yılmaz M, Patlar B, Emecen G, Durmaz E, Magwire MM, Zhou S, Huang W, Anholt RRH, Mackay TFC. Epistasis for head morphology in Drosophila melanogaster. G3 (Bethesda, Md.). 11. PMID 34568933 DOI: 10.1093/g3journal/jkab285  0.462
2021 Baker BM, Carbone MA, Huang W, Anholt RRH, Mackay TFC. Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074789 DOI: 10.1073/pnas.2104131118  0.408
2020 Huang W, Carbone MA, Lyman RF, Anholt RRH, Mackay TFC. Genotype by environment interaction for gene expression in Drosophila melanogaster. Nature Communications. 11: 5451. PMID 33116142 DOI: 10.1038/s41467-020-19131-y  0.372
2020 Morgante F, Huang W, Sørensen P, Maltecca C, Mackay TFC. Leveraging Multiple Layers of Data To Predict Complex Traits. G3 (Bethesda, Md.). PMID 33106232 DOI: 10.1534/g3.120.401847  0.341
2020 Yanagawa A, Huang W, Yamamoto A, Wada-Katsumata A, Schal C, Mackay TFC. Genetic Basis of Natural Variation in Spontaneous Grooming in . G3 (Bethesda, Md.). PMID 32727922 DOI: 10.1534/G3.120.401360  0.37
2020 Everett LJ, Huang W, Zhou S, Carbone MA, Lyman RF, Arya GH, Geisz MS, Ma J, Morgante F, St Armour G, Turlapati L, Anholt RRH, Mackay T. Gene expression networks in the Genetic Reference Panel. Genome Research. PMID 32144088 DOI: 10.1101/Gr.257592.119  0.432
2020 Huang W, Campbell T, Carbone MA, Jones WE, Unselt D, Anholt RRH, Mackay TFC. Context-dependent genetic architecture of Drosophila life span. Plos Biology. 18: e3000645. PMID 32134916 DOI: 10.1371/journal.pbio.3000645  0.406
2020 Parker GA, Kohn N, Spirina A, McMillen A, Huang W, Mackay TFC. Genetic Basis of Increased Lifespan and Postponed Senescence in . G3 (Bethesda, Md.). PMID 31969430 DOI: 10.1534/g3.120.401041  0.437
2019 Zhou S, Morgante F, Geisz M, Ma J, Anholt R, Mackay T. Systems Genetics of the Metabolome. Genome Research. PMID 31694867 DOI: 10.1101/Gr.243030.118  0.456
2019 Highfill CA, Baker BM, Stevens SD, Anholt RRH, Mackay TFC. Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster. Plos Genetics. 15: e1007834. PMID 31107875 DOI: 10.1371/journal.pgen.1007834  0.313
2018 Harbison ST, Kumar S, Huang W, McCoy LJ, Smith KR, Mackay TFC. Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster. Behavior Genetics. PMID 30341464 DOI: 10.1007/S10519-018-9932-0  0.401
2018 Morozova TV, Hussain Y, McCoy LJ, Zhirnov EV, Davis MR, Pray VA, Lyman RA, Duncan LH, McMillen A, Jones A, Mackay TFC, Anholt RRH. A Centered Genetic Network Contributes to Alcohol-Induced Variation in Development. G3 (Bethesda, Md.). PMID 29871898 DOI: 10.1534/g3.118.200260  0.317
2018 Rohde PD, Østergaard S, Kristensen TN, Sørensen P, Loeschcke V, Mackay TFC, Sarup P. Functional Validation of Candidate Genes Detected by Genomic Feature Models. G3 (Bethesda, Md.). PMID 29519937 DOI: 10.1534/G3.118.200082  0.338
2018 Morgante F, Huang W, Maltecca C, Mackay TFC. Effect of genetic architecture on the prediction accuracy of quantitative traits in samples of unrelated individuals. Heredity. PMID 29426878 DOI: 10.1038/s41437-017-0043-0  0.359
2017 Anholt RRH, Mackay TFC. The road less traveled: from genotype to phenotype in flies and humans. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 29058036 DOI: 10.1007/s00335-017-9722-7  0.462
2017 Mackay TFC, Huang W. Charting the genotype-phenotype map: lessons from the Drosophila melanogaster Genetic Reference Panel. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 28834395 DOI: 10.1002/wdev.289  0.483
2017 Zhou S, Luoma SE, St Armour GE, Thakkar E, Mackay TFC, Anholt RRH. A drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure. Plos Genetics. 13: e1006907. PMID 28732062 DOI: 10.1371/Journal.Pgen.1006907  0.382
2017 Garcia JF, Carbone MA, Mackay TFC, Anholt RRH. Regulation of Drosophila Lifespan by bellwether Promoter Alleles. Scientific Reports. 7: 4109. PMID 28646164 DOI: 10.1038/s41598-017-04530-x  0.329
2017 Fochler S, Morozova TV, Davis MR, Gearhart AW, Huang W, Mackay TFC, Anholt RRH. Genetics of Alcohol Consumption in Drosophila melanogaster. Genes, Brain, and Behavior. PMID 28627812 DOI: 10.1111/gbb.12399  0.408
2017 Rohde PD, Gaertner B, Wards K, Sørensen P, Mackay TFC. Genomic Analysis of Genotype by Social Environment Interaction for Drosophila Aggressive Behavior. Genetics. PMID 28550016 DOI: 10.1534/Genetics.117.200642  0.318
2016 Huang W, Mackay TF. The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis. Plos Genetics. 12: e1006421. PMID 27812106 DOI: 10.1371/journal.pgen.1006421  0.43
2016 Carbone MA, Yamamoto A, Huang W, Lyman RA, Meadors TB, Yamamoto R, Anholt RR, Mackay TF. Genetic architecture of natural variation in visual senescence in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 113: E6620-E6629. PMID 27791033 DOI: 10.1073/pnas.1613833113  0.381
2016 Huang W, Lyman RF, Lyman RA, Carbone MA, Harbison ST, Magwire MM, Mackay TF. Correction: Spontaneous mutations and the origin and maintenance of quantitative genetic variation. Elife. 5. PMID 27759564 DOI: 10.7554/Elife.22300  0.339
2016 Friedenberg SG, Meurs KM, Mackay TF. Evaluation of artificial selection in Standard Poodles using whole-genome sequencing. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 27510710 DOI: 10.1007/s00335-016-9660-9  0.346
2016 Gerken AR, Mackay TF, Morgan TJ. Artificial selection on chill-coma recovery time in Drosophila melanogaster: Direct and correlated responses to selection. Journal of Thermal Biology. 59: 77-85. PMID 27264892 DOI: 10.1016/J.Jtherbio.2016.04.004  0.778
2016 Edwards SM, Sørensen IF, Sarup P, Mackay TF, Sørensen P. Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster. Genetics. PMID 27235308 DOI: 10.1534/genetics.116.187161  0.398
2016 Huang W, Lyman RF, Lyman RA, Carbone MA, Harbison ST, Magwire MM, Mackay TF. Spontaneous mutations and the origin and maintenance of quantitative genetic variation. Elife. 5. PMID 27213517 DOI: 10.7554/Elife.14625  0.404
2016 Hunter CM, Huang W, Mackay TF, Singh ND. The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster. Plos Genetics. 12: e1005951. PMID 27035832 DOI: 10.1371/Journal.Pgen.1005951  0.439
2016 Riedl CA, Oster S, Busto M, Mackay TF, Sokolowski MB. Natural variability in Drosophila larval and pupal NaCl tolerance. Journal of Insect Physiology. 88: 15-23. PMID 26874056 DOI: 10.1016/j.jinsphys.2016.02.007  0.36
2016 Vonesch SC, Lamparter D, Mackay TF, Bergmann S, Hafen E. Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster. Plos Genetics. 12: e1005616. PMID 26751788 DOI: 10.1371/Journal.Pgen.1005616  0.42
2016 Gerken AR, Mackay TFC, Morgan TJ. Artificial selection on chill-coma recovery time in Drosophila melanogaster: Direct and correlated responses to selection Journal of Thermal Biology. 59: 77-85. DOI: 10.1016/j.jtherbio.2016.04.004  0.778
2015 He X, Zhou S, St Armour GE, Mackay TF, Anholt RR. Epistatic Partners of Neurogenic Genes Modulate Drosophila Olfactory Behavior. Genes, Brain, and Behavior. PMID 26678546 DOI: 10.1111/gbb.12279  0.446
2015 Zwarts L, Vanden Broeck L, Cappuyns E, Ayroles JF, Magwire MM, Vulsteke V, Clements J, Mackay TF, Callaerts P. The genetic basis of natural variation in mushroom body size in Drosophila melanogaster. Nature Communications. 6: 10115. PMID 26656654 DOI: 10.1038/Ncomms10115  0.716
2015 Dembeck LM, Böröczky K, Huang W, Schal C, Anholt RR, Mackay TF. Genetic architecture of natural variation in cuticularhydrocarbon composition in Drosophila melanogaster. Elife. 4. PMID 26568309 DOI: 10.7554/Elife.09861  0.375
2015 Dembeck LM, Huang W, Carbone MA, Mackay TF. Genetic Basis of Natural Variation in Body Pigmentation in Drosophila melanogaster. Fly. 0. PMID 26554300 DOI: 10.1080/19336934.2015.1102807  0.429
2015 Huang W, Carbone MA, Magwire MM, Peiffer JA, Lyman RF, Stone EA, Anholt RR, Mackay TF. Genetic basis of transcriptome diversity in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. PMID 26483487 DOI: 10.1073/Pnas.1519159112  0.429
2015 Carnes MU, Campbell T, Huang W, Butler DG, Carbone MA, Duncan LH, Harbajan SV, King EM, Peterson KR, Weitzel A, Zhou S, Mackay TF. The Genomic Basis of Postponed Senescence in Drosophila melanogaster. Plos One. 10: e0138569. PMID 26378456 DOI: 10.1371/Journal.Pone.0138569  0.412
2015 Sørensen P, de Los Campos G, Morgante F, Mackay TF, Sorensen D. Genetic Control of Environmental Variation of Two Quantitative Traits of Drosophila melanogaster Revealed by Whole-Genome Sequencing. Genetics. 201: 487-97. PMID 26269504 DOI: 10.1534/genetics.115.180273  0.415
2015 Anholt RR, Mackay TF. Dissecting the Genetic Architecture of Behavior in Drosophila melanogaster. Current Opinion in Behavioral Sciences. 2: 1-7. PMID 26203460 DOI: 10.1016/j.cobeha.2014.06.001  0.401
2015 Ober U, Huang W, Magwire M, Schlather M, Simianer H, Mackay TF. Correction: Accounting for Genetic Architecture Improves Sequence Based Genomic Prediction for a Drosophila Fitness Trait. Plos One. 10: e0132980. PMID 26167869 DOI: 10.1371/journal.pone.0132980  0.301
2015 Shorter J, Couch C, Huang W, Carbone MA, Peiffer J, Anholt RR, Mackay TF. Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 26100892 DOI: 10.1073/Pnas.1510104112  0.471
2015 Ober U, Huang W, Magwire M, Schlather M, Simianer H, Mackay TF. Accounting for genetic architecture improves sequence based genomic prediction for a Drosophila fitness trait. Plos One. 10: e0126880. PMID 25950439 DOI: 10.1371/Journal.Pone.0126880  0.395
2015 Morgante F, Sørensen P, Sorensen DA, Maltecca C, Mackay TF. Genetic Architecture of Micro-Environmental Plasticity in Drosophila melanogaster. Scientific Reports. 5: 9785. PMID 25943032 DOI: 10.1038/srep09785  0.438
2015 Dembeck LM, Huang W, Magwire MM, Lawrence F, Lyman RF, Mackay TF. Genetic Architecture of Abdominal Pigmentation in Drosophila melanogaster. Plos Genetics. 11: e1005163. PMID 25933381 DOI: 10.1371/Journal.Pgen.1005163  0.468
2015 Ivanov DK, Escott-Price V, Ziehm M, Magwire MM, Mackay TF, Partridge L, Thornton JM. Longevity GWAS Using the Drosophila Genetic Reference Panel. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25922346 DOI: 10.1093/Gerona/Glv047  0.389
2015 Arya GH, Magwire MM, Huang W, Serrano-Negron YL, Mackay TF, Anholt RR. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Chemical Senses. 40: 233-43. PMID 25687947 DOI: 10.1093/Chemse/Bjv001  0.345
2015 Gaertner BE, Ruedi EA, McCoy LJ, Moore JM, Wolfner MF, Mackay TF. Heritable variation in courtship patterns in Drosophila melanogaster. G3 (Bethesda, Md.). 5: 531-9. PMID 25650358 DOI: 10.1534/G3.114.014811  0.416
2015 Mackay TF. Epistasis for quantitative traits in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 1253: 47-70. PMID 25403527 DOI: 10.1007/978-1-4939-2155-3_4  0.494
2015 Dembeck LM, Böröczky K, Huang W, Schal C, Anholt RRH, Mackay TFC. Author response: Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster Elife. DOI: 10.7554/Elife.09861.051  0.346
2015 Dembeck LM, Böröczky K, Huang W, Schal C, Anholt RRH, Mackay TFC. Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster Elife. 4. DOI: 10.7554/eLife.09861.001  0.358
2014 Montgomery SL, Vorojeikina D, Huang W, Mackay TF, Anholt RR, Rand MD. Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myogenic and neuromuscular developmental pathways. Plos One. 9: e110375. PMID 25360876 DOI: 10.1371/Journal.Pone.0110375  0.364
2014 Zhou S, Mackay T, Anholt RR. Transcriptional and epigenetic responses to mating and aging in Drosophila melanogaster. Bmc Genomics. 15: 927. PMID 25344338 DOI: 10.1186/1471-2164-15-927  0.324
2014 Ellis LL, Huang W, Quinn AM, Ahuja A, Alfrejd B, Gomez FE, Hjelmen CE, Moore KL, Mackay TF, Johnston JS, Tarone AM. Intrapopulation genome size variation in D. melanogaster reflects life history variation and plasticity. Plos Genetics. 10: e1004522. PMID 25057905 DOI: 10.1371/Journal.Pgen.1004522  0.686
2014 Huang W, Massouras A, Inoue Y, Peiffer J, Ràmia M, Tarone AM, Turlapati L, Zichner T, Zhu D, Lyman RF, Magwire MM, Blankenburg K, Carbone MA, Chang K, Ellis LL, ... Mackay TF, et al. Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. Genome Research. 24: 1193-208. PMID 24714809 DOI: 10.1101/Gr.171546.113  0.728
2014 Mackay TF. Epistasis and quantitative traits: using model organisms to study gene-gene interactions. Nature Reviews. Genetics. 15: 22-33. PMID 24296533 DOI: 10.1038/nrg3627  0.455
2013 Swarup S, Huang W, Mackay TF, Anholt RR. Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. Proceedings of the National Academy of Sciences of the United States of America. 110: 1017-22. PMID 23277560 DOI: 10.1073/Pnas.1220168110  0.385
2013 Wilson RH, Lai CQ, Lyman RF, Mackay TF. Genomic response to selection for postponed senescence in Drosophila. Mechanisms of Ageing and Development. 134: 79-88. PMID 23262286 DOI: 10.1016/J.Mad.2012.11.003  0.353
2012 Massouras A, Waszak SM, Albarca-Aguilera M, Hens K, Holcombe W, Ayroles JF, Dermitzakis ET, Stone EA, Jensen JD, Mackay TF, Deplancke B. Genomic variation and its impact on gene expression in Drosophila melanogaster. Plos Genetics. 8: e1003055. PMID 23189034 DOI: 10.1371/Journal.Pgen.1003055  0.73
2012 Huang W, Richards S, Carbone MA, Zhu D, Anholt RR, Ayroles JF, Duncan L, Jordan KW, Lawrence F, Magwire MM, Warner CB, Blankenburg K, Han Y, Javaid M, Jayaseelan J, ... Mackay TF, et al. Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proceedings of the National Academy of Sciences of the United States of America. 109: 15553-9. PMID 22949659 DOI: 10.1073/Pnas.1213423109  0.746
2012 Anholt RR, Mackay TF. Genetics of aggression. Annual Review of Genetics. 46: 145-64. PMID 22934647 DOI: 10.1146/annurev-genet-110711-155514  0.435
2012 Ober U, Ayroles JF, Stone EA, Richards S, Zhu D, Gibbs RA, Stricker C, Gianola D, Schlather M, Mackay TF, Simianer H. Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster. Plos Genetics. 8: e1002685. PMID 22570636 DOI: 10.1371/Journal.Pgen.1002685  0.68
2012 Zhou S, Campbell TG, Stone EA, Mackay TF, Anholt RR. Phenotypic plasticity of the Drosophila transcriptome. Plos Genetics. 8: e1002593. PMID 22479193 DOI: 10.1371/Journal.Pgen.1002593  0.361
2012 Swarup S, Harbison ST, Hahn LE, Morozova TV, Yamamoto A, Mackay TF, Anholt RR. Extensive epistasis for olfactory behaviour, sleep and waking activity in Drosophila melanogaster. Genetics Research. 94: 9-20. PMID 22353245 DOI: 10.1017/S001667231200002X  0.358
2012 Mackay TF, Richards S, Stone EA, Barbadilla A, Ayroles JF, Zhu D, Casillas S, Han Y, Magwire MM, Cridland JM, Richardson MF, Anholt RR, Barrón M, Bess C, Blankenburg KP, et al. The Drosophila melanogaster Genetic Reference Panel. Nature. 482: 173-8. PMID 22318601 DOI: 10.1038/Nature10811  0.771
2011 Ayroles JF, Laflamme BA, Stone EA, Wolfner MF, Mackay TF. Functional genome annotation of Drosophila seminal fluid proteins using transcriptional genetic networks. Genetics Research. 93: 387-95. PMID 22189604 DOI: 10.1017/S0016672311000346  0.704
2011 Zwarts L, Magwire MM, Carbone MA, Versteven M, Herteleer L, Anholt RR, Callaerts P, Mackay TF. Complex genetic architecture of Drosophila aggressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 108: 17070-5. PMID 21949384 DOI: 10.1073/Pnas.1113877108  0.403
2010 Arya GH, Weber AL, Wang P, Magwire MM, Negron YL, Mackay TF, Anholt RR. Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. Genetics. 186: 1475-85. PMID 20870963 DOI: 10.1534/Genetics.110.123166  0.354
2010 Magwire MM, Yamamoto A, Carbone MA, Roshina NV, Symonenko AV, Pasyukova EG, Morozova TV, Mackay TF. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Plos Genetics. 6: e1001037. PMID 20686706 DOI: 10.1371/Journal.Pgen.1001037  0.656
2010 Desroches CE, Busto M, Riedl CA, Mackay TF, Sokolowski MB. Quantitative trait locus mapping of gravitaxis behaviour in Drosophila melanogaster. Genetics Research. 92: 167-74. PMID 20667161 DOI: 10.1017/S0016672310000194  0.361
2010 Clowers KJ, Lyman RF, Mackay TF, Morgan TJ. Genetic variation in senescence marker protein-30 is associated with natural variation in cold tolerance in Drosophila. Genetics Research. 92: 103-13. PMID 20515514 DOI: 10.1017/S0016672310000108  0.643
2010 Jumbo-Lucioni P, Ayroles JF, Chambers MM, Jordan KW, Leips J, Mackay TF, De Luca M. Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster. Bmc Genomics. 11: 297. PMID 20459830 DOI: 10.1186/1471-2164-11-297  0.748
2010 Mackay TF. Mutations and quantitative genetic variation: lessons from Drosophila. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 1229-39. PMID 20308098 DOI: 10.1098/rstb.2009.0315  0.494
2010 Mackay TFC. Evolutionary genetics quantified Nature Genetics. 42: 1033-1033. DOI: 10.1038/NG1210-1033  0.368
2009 Yamamoto A, Anholt RR, MacKay TF. Epistatic interactions attenuate mutations affecting startle behaviour in Drosophila melanogaster. Genetics Research. 91: 373-82. PMID 19968911 DOI: 10.1017/S0016672309990279  0.407
2009 Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, ... Mackay TF, et al. Finding the missing heritability of complex diseases. Nature. 461: 747-53. PMID 19812666 DOI: 10.1038/Nature08494  0.305
2009 Mackay TF. Genetics. A-maize-ing diversity. Science (New York, N.Y.). 325: 688-9. PMID 19661410 DOI: 10.1126/science.1178420  0.343
2009 Morozova TV, Ayroles JF, Jordan KW, Duncan LH, Carbone MA, Lyman RF, Stone EA, Govindaraju DR, Ellison RC, Mackay TF, Anholt RR. Alcohol sensitivity in Drosophila: translational potential of systems genetics. Genetics. 183: 733-45, 1SI-12SI. PMID 19652175 DOI: 10.1534/Genetics.109.107490  0.684
2009 Edwards AC, Ayroles JF, Stone EA, Carbone MA, Lyman RF, Mackay TF. A transcriptional network associated with natural variation in Drosophila aggressive behavior. Genome Biology. 10: R76. PMID 19607677 DOI: 10.1186/Gb-2009-10-7-R76  0.726
2009 Mackay TF, Stone EA, Ayroles JF. The genetics of quantitative traits: challenges and prospects. Nature Reviews. Genetics. 10: 565-77. PMID 19584810 DOI: 10.1038/Nrg2612  0.746
2009 Mackay TF. Q&A: Genetic analysis of quantitative traits. Journal of Biology. 8: 23. PMID 19435484 DOI: 10.1186/jbiol133  0.318
2009 Edwards AC, Mackay TF. Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics. 182: 889-97. PMID 19414563 DOI: 10.1534/Genetics.109.101691  0.442
2009 Flint J, Mackay TF. Genetic architecture of quantitative traits in mice, flies, and humans. Genome Research. 19: 723-33. PMID 19411597 DOI: 10.1101/gr.086660.108  0.438
2009 Harbison ST, Carbone MA, Ayroles JF, Stone EA, Lyman RF, Mackay TF. Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. Nature Genetics. 41: 371-5. PMID 19234472 DOI: 10.1038/Ng.330  0.654
2009 Ayroles JF, Carbone MA, Stone EA, Jordan KW, Lyman RF, Magwire MM, Rollmann SM, Duncan LH, Lawrence F, Anholt RR, Mackay TF. Systems genetics of complex traits in Drosophila melanogaster. Nature Genetics. 41: 299-307. PMID 19234471 DOI: 10.1038/Ng.332  0.734
2009 Carbone MA, Ayroles JF, Yamamoto A, Morozova TV, West SA, Magwire MM, Mackay TF, Anholt RR. Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma. Plos One. 4: e4216. PMID 19148291 DOI: 10.1371/Journal.Pone.0004216  0.625
2009 Mackay TF. The genetic architecture of complex behaviors: lessons from Drosophila. Genetica. 136: 295-302. PMID 18758968 DOI: 10.1007/s10709-008-9310-6  0.48
2008 Yamamoto A, Zwarts L, Callaerts P, Norga K, Mackay TF, Anholt RR. Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 105: 12393-8. PMID 18713854 DOI: 10.1073/Pnas.0804889105  0.394
2008 Sambandan D, Carbone MA, Anholt RR, Mackay TF. Phenotypic plasticity and genotype by environment interaction for olfactory behavior in Drosophila melanogaster. Genetics. 179: 1079-88. PMID 18505870 DOI: 10.1534/Genetics.108.086769  0.364
2007 Riedl CA, Riedl M, Mackay TF, Sokolowski MB. Genetic and behavioral analysis of natural variation in Drosophila melanogaster pupation position. Fly. 1: 23-32. PMID 18690058 DOI: 10.4161/Fly.3830  0.337
2007 Morozova TV, Anholt RR, Mackay TF. Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. Genome Biology. 8: R231. PMID 17973985 DOI: 10.1186/gb-2007-8-10-r231  0.301
2007 Lai CQ, Leips J, Zou W, Roberts JF, Wollenberg KR, Parnell LD, Zeng ZB, Ordovas JM, Mackay TF. Speed-mapping quantitative trait loci using microarrays. Nature Methods. 4: 839-41. PMID 17873888 DOI: 10.1038/Nmeth1084  0.32
2007 Jordan KW, Carbone MA, Yamamoto A, Morgan TJ, Mackay TF. Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biology. 8: R172. PMID 17708775 DOI: 10.1186/gb-2007-8-8-r172  0.611
2007 Mackay TF, Anholt RR. Ain't misbehavin' ? Genotype-environment interactions and the genetics of behavior. Trends in Genetics : Tig. 23: 311-4. PMID 17418441 DOI: 10.1016/j.tig.2007.03.013  0.325
2006 Edwards AC, Rollmann SM, Morgan TJ, Mackay TF. Quantitative genomics of aggressive behavior in Drosophila melanogaster. Plos Genetics. 2: e154. PMID 17044737 DOI: 10.1371/Journal.Pgen.0020154  0.582
2006 Sambandan D, Yamamoto A, Fanara JJ, Mackay TF, Anholt RR. Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics. 174: 1349-63. PMID 17028343 DOI: 10.1534/Genetics.106.060574  0.334
2006 Rollmann SM, Magwire MM, Morgan TJ, Ozsoy ED, Yamamoto A, Mackay TF, Anholt RR. Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Nature Genetics. 38: 824-9. PMID 16783380 DOI: 10.1038/Ng1823  0.586
2006 Jordan KW, Morgan TJ, Mackay TF. Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics. 174: 271-84. PMID 16783013 DOI: 10.1534/genetics.106.058099  0.642
2006 Mackay TF, Anholt RR. Of flies and man: Drosophila as a model for human complex traits. Annual Review of Genomics and Human Genetics. 7: 339-67. PMID 16756480 DOI: 10.1146/annurev.genom.7.080505.115758  0.415
2006 Wilson RH, Morgan TJ, Mackay TF. High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. Genetics. 173: 1455-63. PMID 16702433 DOI: 10.1534/Genetics.105.055111  0.645
2006 Carbone MA, Jordan KW, Lyman RF, Harbison ST, Leips J, Morgan TJ, DeLuca M, Awadalla P, Mackay TF. Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila. Current Biology : Cb. 16: 912-9. PMID 16682353 DOI: 10.1016/J.Cub.2006.03.051  0.659
2006 Moehring AJ, Llopart A, Elwyn S, Coyne JA, Mackay TF. The genetic basis of postzygotic reproductive isolation between Drosophila santomea and D. yakuba due to hybrid male sterility. Genetics. 173: 225-33. PMID 16510788 DOI: 10.1534/Genetics.105.052985  0.721
2006 Moehring AJ, Llopart A, Elwyn S, Coyne JA, Mackay TF. The genetic basis of prezygotic reproductive isolation between Drosophila santomea and D. yakuba due to mating preference. Genetics. 173: 215-23. PMID 16510787 DOI: 10.1534/Genetics.105.052993  0.714
2006 Morgan TJ, Mackay TF. Quantitative trait loci for thermotolerance phenotypes in Drosophila melanogaster. Heredity. 96: 232-42. PMID 16404413 DOI: 10.1038/sj.hdy.6800786  0.675
2006 Leips J, Gilligan P, Mackay TF. Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster. Genetics. 172: 1595-605. PMID 16272414 DOI: 10.1534/genetics.105.048520  0.348
2005 Mackay TF, Lyman RF. Drosophila bristles and the nature of quantitative genetic variation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 360: 1513-27. PMID 16108138 DOI: 10.1098/Rstb.2005.1672  0.462
2005 Carbone MA, Llopart A, deAngelis M, Coyne JA, Mackay TF. Quantitative trait loci affecting the difference in pigmentation between Drosophila yakuba and D. santomea. Genetics. 171: 211-25. PMID 15972457 DOI: 10.1534/Genetics.105.044412  0.358
2005 Wayne ML, Korol A, Mackay TF. Microclinal variation for ovariole number and body size in Drosophila melanogaster in 'Evolution Canyon'. Genetica. 123: 263-70. PMID 15954497 DOI: 10.1007/S10709-004-5056-Y  0.646
2005 Mackay TF, Lyman RF, Lawrence F. Polygenic mutation in Drosophila melanogaster: Mapping spontaneous mutations affecting sensory bristle number. Genetics. 170: 1723-35. PMID 15944368 DOI: 10.1534/Genetics.104.032581  0.331
2005 Mackay TF, Heinsohn SL, Lyman RF, Moehring AJ, Morgan TJ, Rollmann SM. Genetics and genomics of Drosophila mating behavior. Proceedings of the National Academy of Sciences of the United States of America. 102: 6622-9. PMID 15851659 DOI: 10.1073/Pnas.0501986102  0.788
2005 Harbison ST, Chang S, Kamdar KP, Mackay TF. Quantitative genomics of starvation stress resistance in Drosophila. Genome Biology. 6: R36. PMID 15833123 DOI: 10.1186/gb-2005-6-4-r36  0.393
2005 Mackay TFC, Roshina NV, Leips JW, Pasyukova EG. Complex Genetic Architecture of Drosophila Longevity Handbook of the Biology of Aging. 181-216. DOI: 10.1016/B978-012088387-5/50010-8  0.661
2004 Anholt RR, Mackay TF. Quantitative genetic analyses of complex behaviours in Drosophila. Nature Reviews. Genetics. 5: 838-49. PMID 15520793 DOI: 10.1038/nrg1472  0.404
2004 Pasyukova EG, Roshina NV, Mackay TF. Shuttle craft: a candidate quantitative trait gene for Drosophila lifespan. Aging Cell. 3: 297-307. PMID 15379853 DOI: 10.1111/J.1474-9728.2004.00114.X  0.715
2004 Hill WG, Mackay TF. D. S. Falconer and Introduction to quantitative genetics. Genetics. 167: 1529-36. PMID 15342495  0.521
2004 Moehring AJ, Li J, Schug MD, Smith SG, deAngelis M, Mackay TF, Coyne JA. Quantitative trait loci for sexual isolation between Drosophila simulans and D. mauritiana. Genetics. 167: 1265-74. PMID 15280240 DOI: 10.1534/genetics.103.024364  0.72
2004 Moehring AJ, Mackay TF. The quantitative genetic basis of male mating behavior in Drosophila melanogaster. Genetics. 167: 1249-63. PMID 15280239 DOI: 10.1534/genetics.103.024372  0.702
2004 Pasyukova EG, Nuzhdin SV, Morozova TV, Mackay TF. Accumulation of transposable elements in the genome of Drosophila melanogaster is associated with a decrease in fitness. The Journal of Heredity. 95: 284-90. PMID 15247307 DOI: 10.1093/Jhered/Esh050  0.735
2004 Mackay TF. The genetic architecture of quantitative traits: lessons from Drosophila. Current Opinion in Genetics & Development. 14: 253-7. PMID 15172667 DOI: 10.1016/j.gde.2004.04.003  0.399
2004 Harbison ST, Yamamoto AH, Fanara JJ, Norga KK, Mackay TF. Quantitative trait loci affecting starvation resistance in Drosophila melanogaster. Genetics. 166: 1807-23. PMID 15126400 DOI: 10.1534/Genetics.166.4.1807  0.44
2004 Mackay TF. Methods for genetic dissection of complex traits. Science of Aging Knowledge Environment : Sage Ke. 2004: pe17. PMID 15115850 DOI: 10.1126/sageke.2004.17.pe17  0.352
2004 Genissel A, Pastinen T, Dowell A, Mackay TF, Long AD. No evidence for an association between common nonsynonymous polymorphisms in delta and bristle number variation in natural and laboratory populations of Drosophila melanogaster. Genetics. 166: 291-306. PMID 15020426 DOI: 10.1534/genetics.166.1.291  0.354
2004 Geiger-Thornsberry GL, Mackay TF. Quantitative trait loci affecting natural variation in Drosophila longevity. Mechanisms of Ageing and Development. 125: 179-89. PMID 15013662 DOI: 10.1016/j.mad.2003.12.008  0.406
2003 Ungerer MC, Halldorsdottir SS, Purugganan MD, Mackay TF. Genotype-environment interactions at quantitative trait loci affecting inflorescence development in Arabidopsis thaliana. Genetics. 165: 353-65. PMID 14504242  0.392
2003 Weinig C, Dorn LA, Kane NC, German ZM, Halldorsdottir SS, Ungerer MC, Toyonaga Y, Mackay TF, Purugganan MD, Schmitt J. Heterogeneous selection at specific loci in natural environments in Arabidopsis thaliana. Genetics. 165: 321-9. PMID 14504239  0.453
2003 Anholt RR, Dilda CL, Chang S, Fanara JJ, Kulkarni NH, Ganguly I, Rollmann SM, Kamdar KP, Mackay TF. The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Nature Genetics. 35: 180-4. PMID 12958599 DOI: 10.1038/Ng1240  0.357
2003 Norga KK, Gurganus MC, Dilda CL, Yamamoto A, Lyman RF, Patel PH, Rubin GM, Hoskins RA, Mackay TF, Bellen HJ. Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Current Biology : Cb. 13: 1388-96. PMID 12932322 DOI: 10.1016/S0960-9822(03)00546-3  0.355
2003 De Luca M, Roshina NV, Geiger-Thornsberry GL, Lyman RF, Pasyukova EG, Mackay TF. Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nature Genetics. 34: 429-33. PMID 12881721 DOI: 10.1038/Ng1218  0.713
2002 Lyman RF, Nevo E, Mackay TF. Variation in Drosophila sensory bristle number at 'Evolution Canyon'. Genetical Research. 80: 215-23. PMID 12688660 DOI: 10.1017/S0016672302005876  0.387
2002 Weinig C, Ungerer MC, Dorn LA, Kane NC, Toyonaga Y, Halldorsdottir SS, Mackay TF, Purugganan MD, Schmitt J. Novel loci control variation in reproductive timing in Arabidopsis thaliana in natural environments. Genetics. 162: 1875-84. PMID 12524356  0.342
2002 Dilda CL, Mackay TF. The genetic architecture of Drosophila sensory bristle number. Genetics. 162: 1655-74. PMID 12524340  0.441
2002 Fanara JJ, Robinson KO, Rollmann SM, Anholt RR, Mackay TF. Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior. Genetics. 162: 1321-8. PMID 12454076  0.399
2002 Gibson G, Mackay TF. Enabling population and quantitative genomics. Genetical Research. 80: 1-6. PMID 12448852 DOI: 10.1017/S0016672302005839  0.37
2002 Robin C, Lyman RF, Long AD, Langley CH, Mackay TF. hairy: A quantitative trait locus for drosophila sensory bristle number. Genetics. 162: 155-64. PMID 12242230  0.44
2002 Leips J, Mackay TF. The complex genetic architecture of Drosophila life span. Experimental Aging Research. 28: 361-90. PMID 12227919 DOI: 10.1080/03610730290080399  0.404
2002 Geiger-Thornsberry GL, Mackay TF. Association of single-nucleotide polymorphisms at the Delta locus with genotype by environment interaction for sensory bristle number in drosophila Melanogaster. Genetical Research. 79: 211-8. PMID 12220128 DOI: 10.1017/S0016672302005621  0.335
2002 Ungerer MC, Halldorsdottir SS, Modliszewski JL, Mackay TF, Purugganan MD. Quantitative trait loci for inflorescence development in Arabidopsis thaliana. Genetics. 160: 1133-51. PMID 11901129  0.46
2002 Mackay TF. The nature of quantitative genetic variation for Drosophila longevity. Mechanisms of Ageing and Development. 123: 95-104. PMID 11718804 DOI: 10.1016/S0047-6374(01)00330-X  0.42
2002 Mackay TF. The genetic architecture of quantitative traits. Annual Review of Genetics. 35: 303-39. PMID 11700286 DOI: 10.1146/ANNUREV.GENET.35.102401.090633  0.473
2001 Anholt RR, Mackay TF. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Behavior Genetics. 31: 17-27. PMID 11529271 DOI: 10.1023/A:1010201723966  0.347
2001 Wayne ML, Hackett JB, Dilda CL, Nuzhdin SV, Pasyukova EG, Mackay TF. Quantitative trait locus mapping of fitness-related traits in Drosophila melanogaster. Genetical Research. 77: 107-16. PMID 11279827 DOI: 10.1017/S0016672300004894  0.804
2001 Mackay TF. Quantitative trait loci in Drosophila. Nature Reviews. Genetics. 2: 11-20. PMID 11253063 DOI: 10.1038/35047544  0.462
1999 Lyman RF, Lai C, MacKay TF. Linkage disequilibrium mapping of molecular polymorphisms at the scabrous locus associated with naturally occurring variation in bristle number in Drosophila melanogaster. Genetical Research. 74: 303-11. PMID 10689806 DOI: 10.1017/S001667239900419X  0.397
1999 Nuzhdin SV, Dilda CL, Mackay TF. The genetic architecture of selection response. Inferences from fine-scale mapping of bristle number quantitative trait loci in Drosophila melanogaster. Genetics. 153: 1317-31. PMID 10545462  0.644
1999 Gurganus MC, Nuzhdin SV, Leips JW, Mackay TF. High-resolution mapping of quantitative trait loci for sternopleural bristle number in Drosophila melanogaster. Genetics. 152: 1585-604. PMID 10430585  0.64
1999 Mackay TFC, Lynch M, Walsh B. Quantitative Genetics Evolution. 53: 307. DOI: 10.2307/2640946  0.348
1998 Fry JD, Nuzhdin SV, Pasyukova EG, Mackay TF. QTL mapping of genotype-environment interaction for fitness in Drosophila melanogaster. Genetical Research. 71: 133-41. PMID 9717436 DOI: 10.1017/S0016672398003176  0.757
1998 Gurganus MC, Fry JD, Nuzhdin SV, Pasyukova EG, Lyman RF, Mackay TF. Genotype-environment interaction at quantitative trait loci affecting sensory bristle number in Drosophila melanogaster. Genetics. 149: 1883-98. PMID 9691044  0.788
1998 Wayne ML, Mackay TF. Quantitative genetics of ovariole number in Drosophila melanogaster. II. Mutational variation and genotype-environment interaction. Genetics. 148: 201-10. PMID 9475732  0.613
1998 Mackay TFC, Roff DA. Quantitative Genetics and Phenotypic Evolution Evolution. 52: 635. DOI: 10.2307/2411100  0.401
1998 Mackay TFC. QUANTITATIVE GENETICS AND PHENOTYPIC EVOLUTION Evolution. 52: 635-640. DOI: 10.1111/J.1558-5646.1998.TB01664.X  0.401
1997 Wayne ML, Hackett JB, Mackay TFC. QUANTITATIVE GENETICS OF OVARIOLE NUMBER IN DROSOPHILA MELANOGASTER. I. SEGREGATING VARIATION AND FITNESS. Evolution; International Journal of Organic Evolution. 51: 1156-1163. PMID 28565484 DOI: 10.1111/J.1558-5646.1997.Tb03963.X  0.682
1997 Nuzhdin SV, Pasyukova EG, Mackay TF. Accumulation of transposable elements in laboratory lines of Drosophila melanogaster. Genetica. 100: 167-75. PMID 9440270 DOI: 10.1023/A:1018381512384  0.725
1997 Nuzhdin SV, Pasyukova EG, Dilda CL, Zeng ZB, Mackay TF. Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 94: 9734-9. PMID 9275193 DOI: 10.1073/Pnas.94.18.9734  0.758
1996 Fry JD, Heinsohn SL, Mackay TFC. THE CONTRIBUTION OF NEW MUTATIONS TO GENOTYPE-ENVIRONMENT INTERACTION FOR FITNESS IN DROSOPHILA MELANOGASTER. Evolution; International Journal of Organic Evolution. 50: 2316-2327. PMID 28565671 DOI: 10.1111/j.1558-5646.1996.tb03619.x  0.362
1996 Mackay TF, Hackett JB, Lyman RF, Wayne ML, Anholt RR. Quantitative genetic variation of odor-guided behavior in a natural population of Drosophila melanogaster. Genetics. 144: 727-35. PMID 8889533  0.653
1996 Mackay TF. The nature of quantitative genetic variation revisited: lessons from Drosophila bristles. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 113-21. PMID 8851044 DOI: 10.1002/BIES.950180207  0.459
1996 Nuzhdin SV, Pasyukova EG, Mackay TF. Positive association between copia transposition rate and copy number in Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 263: 823-31. PMID 8760490 DOI: 10.1098/Rspb.1996.0122  0.717
1996 Lyman RF, Lawrence F, Nuzhdin SV, Mackay TF. Effects of single P-element insertions on bristle number and viability in Drosophila melanogaster. Genetics. 143: 277-92. PMID 8722781  0.548
1996 Mackay TF. The genetic basis of quantitative variation: numbers of sensory bristles of Drosophila melanogaster as a model system. Trends in Genetics : Tig. 11: 464-70. PMID 8533161 DOI: 10.1016/S0168-9525(00)89154-4  0.449
1995 Nuzhdin SV, Mackay TF. The genomic rate of transposable element movement in Drosophila melanogaster. Molecular Biology and Evolution. 12: 180-1. PMID 7877494  0.505
1995 Nuzhdin SV, Fry JD, Mackay TF. Polygenic mutation in Drosophila melanogaster: the causal relationship of bristle number to fitness. Genetics. 139: 861-72. PMID 7713437  0.556
1994 Nuzhdin SV, Mackay TF. Direct determination of retrotransposon transposition rates in Drosophila melanogaster. Genetical Research. 63: 139-44. PMID 8026740  0.528
1994 Mackay TF, Fry JD, Lyman RF, Nuzhdin SV. Polygenic mutation in Drosophila melanogaster: estimates from response to selection of inbred strains. Genetics. 136: 937-51. PMID 8005446  0.582
1994 Lai C, Lyman RF, Long AD, Langley CH, Mackay TF. Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Drosophila melanogaster. Science (New York, N.Y.). 266: 1697-702. PMID 7992053 DOI: 10.1126/Science.7992053  0.415
1993 Lai C, Mackay TF. Mapping and characterization of P-element-induced mutations at quantitative trait loci in Drosophila melanogaster. Genetical Research. 61: 177-93. PMID 8396063 DOI: 10.1017/S0016672300031359  0.308
1992 Mackay TFC, Lyman RF, Jackson MS, Terzian C, Hill WG. POLYGENIC MUTATION IN DROSOPHILA MELANOGASTER: ESTIMATES FROM DIVERGENCE AMONG INBRED STRAINS. Evolution; International Journal of Organic Evolution. 46: 300-316. PMID 28564027 DOI: 10.1111/J.1558-5646.1992.Tb02039.X  0.564
1990 Pignatelli PM, Mackay TF. Hybrid dysgenesis-induced response to selection in Drosophila melanogaster. Genetical Research. 54: 183-95. PMID 2559871 DOI: 10.1017/S0016672300028640  0.325
1990 Mackay TFC, Langley CH. Molecular and phenotypic variation in the achaete-scute region of Drosophila melanogaster Nature. 348: 64-66. PMID 2122256  0.429
1986 Mackay TFC. A quantitative genetic analysis of fitness and its components in Drosophila melanogaster Genetical Research. 47: 59-70. DOI: 10.1017/S0016672300024526  0.383
1985 Mackay TFC. TRANSPOSABLE ELEMENT-INDUCED RESPONSE TO ARTIFICIAL SELECTION IN DROSOPHILA MELANOGASTER Genetics. 111: 351-374. DOI: 10.1093/genetics/111.2.351  0.333
1984 Mackay TFC. Jumping genes meet abdominal bristles: hybrid dysgenesis-induced quantitative variation in Drosophila melanogaster Genetical Research. 44: 231-237. DOI: 10.1017/S0016672300026422  0.372
1981 Mackay TFC. Genetic variation in varying environments Genetical Research. 37: 79-93. DOI: 10.1017/S0016672300020036  0.368
1978 Mackay TFC, Doyle RW. An ecological genetic analysis of the settling behaviour of a marine polychaete: Heredity. 40: 1-12. DOI: 10.1038/hdy.1978.1  0.335
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