Year |
Citation |
Score |
2023 |
Burris TP, de Vera IMS, Cote I, Flaveny CA, Wanninayake US, Chatterjee A, Walker JK, Steinauer N, Zhang J, Coons LA, Korach KS, Cain DW, Hollenberg AN, Webb P, Forrest D, ... ... Edwards DP, et al. . Pharmacological Reviews. PMID 37586884 DOI: 10.1124/pharmrev.121.000436 |
0.678 |
|
2021 |
Strutzenberg TS, Zhu Y, Novick SJ, Garcia-Ordonez RD, Doebelin C, He Y, Ra Chang M, Kamenecka TM, Edwards DP, Griffin PR. Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement. Journal of Molecular Biology. 167258. PMID 34547329 DOI: 10.1016/j.jmb.2021.167258 |
0.393 |
|
2020 |
Asavasupreechar T, Saito R, Miki Y, Edwards DP, Boonyaratanakornkit V, Sasano H. Systemic distribution of progesterone receptor subtypes in human tissues. The Journal of Steroid Biochemistry and Molecular Biology. 105599. PMID 31991170 DOI: 10.1016/J.Jsbmb.2020.105599 |
0.368 |
|
2020 |
Asavasupreechar T, Saito R, Miki Y, Edwards DP, Boonyaratanakornkit V, Sasano H. SUN-742 Roles of Progesterone Receptor Isoform B in Non-Small Cell Lung Cancer Tumor Progression Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1568 |
0.31 |
|
2019 |
Asavasupreechar T, Saito R, Edwards DP, Sasano H, Boonyaratanakornkit V. Progesterone Receptor Isoform B Expression in Pulmonary Neuroendocrine Cells Decreases Cell Proliferation. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30926428 DOI: 10.1016/J.Jsbmb.2019.03.022 |
0.313 |
|
2019 |
Finnerty BM, Moore M, Verma A, Aronova A, Huang S, Edwards DP, Chen Z, Seandel M, Scognamiglio T, Du N, Elemento O, Zarnegar R, Min IM, Fahey TJ. UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors. Endocrine-Related Cancer. PMID 30689542 DOI: 10.1530/Erc-18-0507 |
0.312 |
|
2019 |
Cain D, Cidlowski J, Edwards DP, Fuller P, Grimm SL, Hartig S, Lange CA, Oakley RH, Richer JK, Sartorius CA, Tetel M, Weigel N, Young M. 3C. 3-Ketosteroid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f98/2019.4 |
0.702 |
|
2018 |
Villanueva H, Grimm SL, Dhamne S, Rajapakshe K, Visbal AP, Davis CM, Ehli EA, Hartig SM, Coarfa C, Edwards DP. Correction to: The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast. Journal of Mammary Gland Biology and Neoplasia. PMID 30465315 DOI: 10.1007/S10911-018-9421-3 |
0.368 |
|
2018 |
Villanueva H, Grimm S, Dhamne S, Rajapakshe K, Visbal A, Davis CM, Ehli EA, Hartig SM, Coarfa C, Edwards DP. The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast. Journal of Mammary Gland Biology and Neoplasia. PMID 30338425 DOI: 10.1007/S10911-018-9416-0 |
0.405 |
|
2018 |
Hai L, Szwarc MM, Wetendorf M, Wu SP, Peavey MC, Grimm SL, Edwards DP, DeMayo FJ, Lydon JP. A mouse model engineered to conditionally express the progesterone receptor-B isoform. Genesis (New York, N.Y. : 2000). PMID 30004627 DOI: 10.1002/Dvg.23223 |
0.309 |
|
2018 |
Singh R, Karri D, Shen H, Shao J, Dasgupta S, Huang S, Edwards DP, Ittmann MM, O'Malley BW, Yi P. TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis. The Journal of Clinical Investigation. PMID 29715200 DOI: 10.1172/Jci96060 |
0.347 |
|
2018 |
Haricharan S, Punturi N, Singh P, Holloway K, Anurag M, Schmelz J, Schmidt C, Lei J, Suman V, Hunt K, Olson J, Hoog J, Li S, Huang S, Edwards D, et al. Abstract P4-04-01: Loss of mismatch repair predicts resistance to endocrine therapy and sensitivity to CDK4/6 inhibitors in ER+ breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P4-04-01 |
0.332 |
|
2018 |
Singh R, Karri D, Shao J, Dasgupta S, Huang S, Edwards DP, O'Malley BW, Yi P. Abstract 1084: TRAF4-mediated NGF receptor TrkA ubiquitination regulates prostate cancer metastasis Cancer Research. 78: 1084-1084. DOI: 10.1158/1538-7445.Am2018-1084 |
0.36 |
|
2018 |
Shneider BL, Krishnamoorthy S, Schady D, Cortes-Santiago N, Thevananther S, Huang S, Rajapakshe K, Coarfa C, Edwards D, Shroyer NF, Finegold MJ. Tu1273 - Expression of Constitutively Active Mitogen-Activated Protein Kinase 1 (MEK1) Profoundly Disrupts Ileal Epithelial Homeostasis Gastroenterology. 154: S-921. DOI: 10.1016/S0016-5085(18)33099-3 |
0.313 |
|
2017 |
Acharya KD, Nettles SA, Sellers KJ, Im DD, Harling M, Pattanayak C, Vardar-Ulu D, Lichti CF, Huang S, Edwards DP, Srivastava DP, Denner L, Tetel MJ. The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent. Eneuro. 4. PMID 28955722 DOI: 10.1523/ENEURO.0272-17.2017 |
0.791 |
|
2017 |
Haricharan S, Punturi N, Singh P, Holloway KR, Anurag M, Schmelz J, Schmidt C, Lei JT, Suman V, Hunt K, Olson JA, Hoog J, Li S, Huang S, Edwards DP, et al. Loss of MutL Disrupts Chk2-dependent Cell Cycle Control Through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer Discovery. PMID 28801307 DOI: 10.1158/2159-8290.Cd-16-1179 |
0.327 |
|
2017 |
Valdez KE, Elsarraj HS, Hong Y, Grimm SL, Ricci LR, Fan F, Tawfik O, May L, Cusick T, Inciardi M, Redick M, Gatewood J, Winblad O, Hilsenbeck SG, Edwards DP, et al. NEMO, a transcriptional target of estrogen and progesterone, is linked to tumor suppressor PML in breast cancer. Cancer Research. PMID 28515148 DOI: 10.1158/0008-5472.Can-16-2794 |
0.395 |
|
2017 |
Fu X, Pereira R, Zhao D, Jung S, Jeselsohn R, Creighton C, Shea M, Nardone A, Angelis C, Tsimelzon A, Wang T, Gutierrez C, Huang S, Edwards D, Rimawi M, et al. Abstract PD2-04: FOXA1 induces a pro-metastatic secretome through ER-dependent and independent transcriptional reprogramming in endocrine-resistant breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Pd2-04 |
0.302 |
|
2017 |
Haricharan S, Schmelz J, Schmidt C, Singh P, Holloway KR, Anurag M, Li S, Kavuri SM, Huang S, Edwards DP, Suman V, Hunt K, Olson JA, Hoog J, Ma CX, et al. Abstract 489: Mismatch repair defects and endocrine therapy resistance in estrogen receptor positive breast cancer Cancer Research. 77: 489-489. DOI: 10.1158/1538-7445.Am2017-489 |
0.353 |
|
2016 |
Fu X, Jeselsohn R, Pereira R, Hollingsworth EF, Creighton CJ, Li F, Shea M, Nardone A, De Angelis C, Heiser LM, Anur P, Wang N, Grasso CS, Spellman PT, Griffith OL, ... ... Edwards DP, et al. FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 113: E6600-E6609. PMID 27791031 DOI: 10.1073/Pnas.1612835113 |
0.366 |
|
2016 |
Kim JA, Tan Y, Wang X, Cao X, Veeraraghavan J, Liang Y, Edwards DP, Huang S, Pan X, Li K, Schiff R, Wang XS. Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers. Nature Communications. 7: 12991. PMID 27694828 DOI: 10.1038/Ncomms12991 |
0.337 |
|
2016 |
Grimm SL, Hartig SM, Edwards DP. Progesterone Receptor Signaling Mechanisms. Journal of Molecular Biology. PMID 27380738 DOI: 10.1016/J.Jmb.2016.06.020 |
0.494 |
|
2016 |
Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, ... ... Edwards DP, et al. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nature Communications. 7: 11612. PMID 27194471 DOI: 10.1038/Ncomms11612 |
0.366 |
|
2016 |
Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, ... ... Edwards DP, et al. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nature Cell Biology. PMID 27183469 DOI: 10.1038/Ncb3355 |
0.31 |
|
2016 |
Treviño LS, Bolt MJ, Grimm SL, Edwards DP, Mancini MA, Weigel NL. Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK. Molecular Endocrinology (Baltimore, Md.). 30: 158-72. PMID 26652902 DOI: 10.1210/Me.2015-1144 |
0.54 |
|
2016 |
Elsarraj H, Yan H, Knapp J, Tsimelzon A, Huang S, Godwin A, Hilsenbeck S, Edwards D, Behbod F. Abstract B01: B cell lymphoma 9 mediates a cross talk between the canonical Wnt and EGFR signaling in breast cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B01 |
0.379 |
|
2015 |
Chang CH, Zhang M, Rajapakshe K, Coarfa C, Edwards D, Huang S, Rosen JM. Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports. PMID 26300228 DOI: 10.1016/J.Stemcr.2015.07.009 |
0.34 |
|
2015 |
Qin L, Hahn MB, Fu X, Shea MJ, Giuliano M, Nanda S, Xu X, Hu H, Jung SY, Heiser LM, Wang N, Gray JW, Hilsenbeck SG, Creighton C, Shaw CA, ... ... Edwards DP, et al. Abstract P3-05-13: Overexpression of insulin receptor substrate 4 can mediate acquired resistance to lapatinib-containing regimens in HER2+ breast cancer cells Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-13 |
0.323 |
|
2015 |
Veeraraghavan J, Tan Y, Cao X, Kim J, Wang X, Edwards DP, Contreras A, Hilsenbeck SG, Chang EC, Schiff R, Wang X. Abstract P1-07-07: Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of estrogen-receptor positive breast cancers Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-07-07 |
0.383 |
|
2015 |
Kim J, Tan Y, Wang X, Cao X, Veeraraghavan J, Liang Y, Edwards DP, Pan X, Li K, Schiff R, Wang X. Abstract 3032: Genomic deregulation and therapeutic role of the cell-cycle kinase TLK2 in more aggressive breast cancers Cancer Research. 75: 3032-3032. DOI: 10.1158/1538-7445.Am2015-3032 |
0.303 |
|
2014 |
Karlin KL, Mondal G, Hartman JK, Tyagi S, Kurley SJ, Bland CS, Hsu TY, Renwick A, Fang JE, Migliaccio I, Callaway C, Nair A, Dominguez-Vidana R, Nguyen DX, Osborne CK, ... ... Edwards DP, et al. The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Reports. 9: 1318-32. PMID 25453754 DOI: 10.1016/J.Celrep.2014.10.011 |
0.323 |
|
2014 |
Grimm SL, Ward RD, Obr AE, Franco HL, Fernandez-Valdivia R, Kim JS, Roberts JM, Jeong JW, DeMayo FJ, Lydon JP, Edwards DP, Weigel NL. A role for site-specific phosphorylation of mouse progesterone receptor at serine 191 in vivo. Molecular Endocrinology (Baltimore, Md.). 28: 2025-37. PMID 25333515 DOI: 10.1210/Me.2014-1206 |
0.455 |
|
2014 |
Bharadwaj U, Kasembeli MM, Eckols TK, Kolosov M, Lang P, Christensen K, Edwards DP, Tweardy DJ. Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer. Cancers. 6: 2012-34. PMID 25268166 DOI: 10.3390/Cancers6042012 |
0.378 |
|
2014 |
Moore NL, Edwards DP, Weigel NL. Cyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 144: 471-82. PMID 25220500 DOI: 10.1016/J.Jsbmb.2014.09.009 |
0.369 |
|
2014 |
Veeraraghavan J, Tan Y, Cao XX, Kim JA, Wang X, Chamness GC, Maiti SN, Cooper LJ, Edwards DP, Contreras A, Hilsenbeck SG, Chang EC, Schiff R, Wang XS. Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers. Nature Communications. 5: 4577. PMID 25099679 DOI: 10.1038/Ncomms5577 |
0.353 |
|
2014 |
Goswami D, Callaway C, Pascal BD, Kumar R, Edwards DP, Griffin PR. Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry. Structure (London, England : 1993). 22: 961-73. PMID 24909783 DOI: 10.1016/J.Str.2014.04.013 |
0.479 |
|
2014 |
Pathiraja TN, Nayak SR, Xi Y, Jiang S, Garee JP, Edwards DP, Lee AV, Chen J, Shea MJ, Santen RJ, Gannon F, Kangaspeska S, Jelinek J, Issa JP, Richer JK, et al. Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer. Science Translational Medicine. 6: 229ra41. PMID 24670685 DOI: 10.1126/Scitranslmed.3008326 |
0.381 |
|
2014 |
Simons SS, Edwards DP, Kumar R. Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges. Molecular Endocrinology (Baltimore, Md.). 28: 173-82. PMID 24284822 DOI: 10.1210/Me.2013-1334 |
0.457 |
|
2013 |
Obr AE, Grimm SL, Bishop KA, Pike JW, Lydon JP, Edwards DP. Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells. Molecular Endocrinology (Baltimore, Md.). 27: 1808-24. PMID 24014651 DOI: 10.1210/Me.2013-1077 |
0.502 |
|
2013 |
Kumar R, Moure CM, Khan SH, Callaway C, Grimm SL, Goswami D, Griffin PR, Edwards DP. Regulation of the structurally dynamic N-terminal domain of progesterone receptor by protein-induced folding. The Journal of Biological Chemistry. 288: 30285-99. PMID 23995840 DOI: 10.1074/Jbc.M113.491787 |
0.507 |
|
2013 |
Foulds CE, Feng Q, Ding C, Bailey S, Hunsaker TL, Malovannaya A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway CG, Edwards DP, Lonard DM, et al. Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics. Molecular Cell. 51: 185-99. PMID 23850489 DOI: 10.1016/J.Molcel.2013.06.007 |
0.457 |
|
2013 |
Nickisch K, Nair HB, Kesavaram N, Das B, Garfield R, Shi SQ, Bhaskaran SS, Grimm SL, Edwards DP. Synthesis and antiprogestational properties of novel 17-fluorinated steroids. Steroids. 78: 909-19. PMID 23607964 DOI: 10.1016/J.Steroids.2013.04.003 |
0.413 |
|
2013 |
Treviño LS, Bingman WE, Edwards DP, Nl W. The requirement for p42/p44 MAPK activity in progesterone receptor-mediated gene regulation is target gene-specific. Steroids. 78: 542-7. PMID 23380370 DOI: 10.1016/J.Steroids.2012.12.014 |
0.406 |
|
2012 |
Smith CL, Migliaccio I, Chaubal V, Wu MF, Pace MC, Hartmaier R, Jiang S, Edwards DP, Gutiérrez MC, Hilsenbeck SG, Oesterreich S. Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence. Breast Cancer Research and Treatment. 136: 253-65. PMID 23015261 DOI: 10.1007/S10549-012-2262-7 |
0.423 |
|
2012 |
Obr AE, Edwards DP. The biology of progesterone receptor in the normal mammary gland and in breast cancer. Molecular and Cellular Endocrinology. 357: 4-17. PMID 22193050 DOI: 10.1016/J.Mce.2011.10.030 |
0.418 |
|
2012 |
Gao R, Zhao L, Liu X, Rowan BG, Wabitsch M, Edwards DP, Nishi Y, Yanase T, Yu Q, Dong Y. Methylseleninic acid is a novel suppressor of aromatase expression. The Journal of Endocrinology. 212: 199-205. PMID 22128327 DOI: 10.1530/Joe-11-0363 |
0.345 |
|
2012 |
Hill KK, Roemer SC, Churchill ME, Edwards DP. Structural and functional analysis of domains of the progesterone receptor. Molecular and Cellular Endocrinology. 348: 418-29. PMID 21803119 DOI: 10.1016/J.Mce.2011.07.017 |
0.828 |
|
2012 |
Oesterreich S, Kitchens C, Gavin P, Wu C, Riehle K, Coarfa C, Edwards D, Schiff R, Milosavljevic A, Lee A. Abstract P6-05-12: Lack of Frequent Estrogen Receptor Mutation in Primary Breast Tumors Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P6-05-12 |
0.345 |
|
2011 |
Garza AS, Khan SH, Moure CM, Edwards DP, Kumar R. Binding-folding induced regulation of AF1 transactivation domain of the glucocorticoid receptor by a cofactor that binds to its DNA binding domain. Plos One. 6: e25875. PMID 22003412 DOI: 10.1371/Journal.Pone.0025875 |
0.499 |
|
2011 |
Buser AC, Obr AE, Kabotyanski EB, Grimm SL, Rosen JM, Edwards DP. Progesterone receptor directly inhibits β-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications. Molecular Endocrinology (Baltimore, Md.). 25: 955-68. PMID 21527503 DOI: 10.1210/Me.2011-0064 |
0.8 |
|
2010 |
Kobayashi S, Stice JP, Kazmin D, Wittmann BM, Kimbrel EA, Edwards DP, Chang CY, McDonnell DP. Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer. Molecular Endocrinology (Baltimore, Md.). 24: 2292-302. PMID 20980435 DOI: 10.1210/Me.2010-0289 |
0.452 |
|
2010 |
Greger JG, Fursov N, Cooch N, McLarney S, Freedman LP, Edwards DP, Cheskis BJ. Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase (Molecular and Cellular Biology (2007) 27, 5, (1904-1913)) Molecular and Cellular Biology. 30: 1568. PMID 20194629 DOI: 10.1128/Mcb.00090-10 |
0.301 |
|
2010 |
Wardell SE, Narayanan R, Weigel NL, Edwards DP. Partial agonist activity of the progesterone receptor antagonist RU486 mediated by an amino-terminal domain coactivator and phosphorylation of serine400. Molecular Endocrinology (Baltimore, Md.). 24: 335-45. PMID 20008003 DOI: 10.1210/Me.2008-0081 |
0.739 |
|
2010 |
Kobayashi S, Stice JP, Kazmin D, Wittmann BM, Kimbrel EA, Edwards DP, Chang C, McDonnell DP. Mechanisms of Progesterone Receptor Inhibition of Inflammatory Responses in Cellular Models of Breast Cancer Endocrine Reviews. 31: 5457-5457. DOI: 10.1210/Edrv.31.6.9984 |
0.375 |
|
2009 |
Holley AK, Kiningham KK, Spitz DR, Edwards DP, Jenkins JT, Moore MR. Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 117: 23-30. PMID 19563893 DOI: 10.1016/J.Jsbmb.2009.06.004 |
0.35 |
|
2009 |
Hill KK, Roemer SC, Jones DN, Churchill ME, Edwards DP. A progesterone receptor co-activator (JDP2) mediates activity through interaction with residues in the carboxyl-terminal extension of the DNA binding domain. The Journal of Biological Chemistry. 284: 24415-24. PMID 19553667 DOI: 10.1074/Jbc.M109.003244 |
0.823 |
|
2009 |
Lydon JP, Edwards DP. Finally! A model for progesterone receptor action in normal human breast. Endocrinology. 150: 2988-90. PMID 19549883 DOI: 10.1210/En.2009-0383 |
0.365 |
|
2009 |
Kabotyanski EB, Rijnkels M, Freeman-Zadrowski C, Buser AC, Edwards DP, Rosen JM. Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements. The Journal of Biological Chemistry. 284: 22815-24. PMID 19542223 DOI: 10.1074/Jbc.M109.032490 |
0.797 |
|
2008 |
Fernandez-Valdivia R, Mukherjee A, Creighton CJ, Buser AC, DeMayo FJ, Edwards DP, Lydon JP. Transcriptional response of the murine mammary gland to acute progesterone exposure. Endocrinology. 149: 6236-50. PMID 18687774 DOI: 10.1210/En.2008-0768 |
0.788 |
|
2008 |
Roemer SC, Adelman J, Churchill ME, Edwards DP. Mechanism of high-mobility group protein B enhancement of progesterone receptor sequence-specific DNA binding. Nucleic Acids Research. 36: 3655-66. PMID 18474528 DOI: 10.1093/Nar/Gkn249 |
0.768 |
|
2008 |
Boonyaratanakornkit V, Bi Y, Rudd M, Edwards DP. The role and mechanism of progesterone receptor activation of extra-nuclear signaling pathways in regulating gene transcription and cell cycle progression. Steroids. 73: 922-8. PMID 18321550 DOI: 10.1016/J.Steroids.2008.01.010 |
0.5 |
|
2007 |
McGowan EM, Russell AJ, Boonyaratanakornkit V, Saunders DN, Lehrbach GM, Sergio CM, Musgrove EA, Edwards DP, Sutherland RL. Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor. Cancer Research. 67: 8942-51. PMID 17875737 DOI: 10.1158/0008-5472.Can-07-1255 |
0.459 |
|
2007 |
Boonyaratanakornkit V, Edwards DP. Receptor mechanisms mediating non-genomic actions of sex steroids. Seminars in Reproductive Medicine. 25: 139-53. PMID 17447204 DOI: 10.1055/S-2007-973427 |
0.48 |
|
2007 |
Carnevale RP, Proietti CJ, Salatino M, Urtreger A, Peluffo G, Edwards DP, Boonyaratanakornkit V, Charreau EH, Bal de Kier Joffé E, Schillaci R, Elizalde PV. Progestin effects on breast cancer cell proliferation, proteases activation, and in vivo development of metastatic phenotype all depend on progesterone receptor capacity to activate cytoplasmic signaling pathways. Molecular Endocrinology (Baltimore, Md.). 21: 1335-58. PMID 17440047 DOI: 10.1210/Me.2006-0304 |
0.44 |
|
2007 |
Greger JG, Fursov N, Cooch N, McLarney S, Freedman LP, Edwards DP, Cheskis BJ. Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 27: 1904-13. PMID 17194752 DOI: 10.1128/Mcb.01732-06 |
0.404 |
|
2007 |
Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP. The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Molecular Endocrinology (Baltimore, Md.). 21: 359-75. PMID 17138644 DOI: 10.1210/Me.2006-0337 |
0.505 |
|
2007 |
Buser AC, Gass-Handel EK, Wyszomierski SL, Doppler W, Leonhardt SA, Schaack J, Rosen JM, Watkin H, Anderson SM, Edwards DP. Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Molecular Endocrinology (Baltimore, Md.). 21: 106-25. PMID 16973758 DOI: 10.1210/Me.2006-0297 |
0.804 |
|
2006 |
Roemer SC, Donham DC, Sherman L, Pon VH, Edwards DP, Churchill ME. Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements. Molecular Endocrinology (Baltimore, Md.). 20: 3042-52. PMID 16931575 DOI: 10.1210/Me.2005-0511 |
0.784 |
|
2006 |
Brayman MJ, Julian J, Mulac-Jericevic B, Conneely OM, Edwards DP, Carson DD. Progesterone receptor isoforms A and B differentially regulate MUC1 expression in uterine epithelial cells. Molecular Endocrinology (Baltimore, Md.). 20: 2278-91. PMID 16740655 DOI: 10.1210/Me.2005-0343 |
0.448 |
|
2006 |
Long DL, Doherty DH, Eisenberg SP, Smith DJ, Rosendahl MS, Christensen KR, Edwards DP, Chlipala EA, Cox GN. Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity. Experimental Hematology. 34: 697-704. PMID 16728273 DOI: 10.1016/J.Exphem.2006.02.011 |
0.32 |
|
2005 |
Wardell SE, Kwok SC, Sherman L, Hodges RS, Edwards DP. Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism. Molecular and Cellular Biology. 25: 8792-808. PMID 16199860 DOI: 10.1128/Mcb.25.20.8792-8808.2005 |
0.708 |
|
2005 |
Igarashi TM, Bruner-Tran KL, Yeaman GR, Lessey BA, Edwards DP, Eisenberg E, Osteen KG. Reduced expression of progesterone receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fertility and Sterility. 84: 67-74. PMID 16009159 DOI: 10.1016/J.Fertnstert.2005.01.113 |
0.325 |
|
2005 |
Narayanan R, Edwards DP, Weigel NL. Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity. Molecular and Cellular Biology. 25: 2885-98. PMID 15798179 DOI: 10.1128/Mcb.25.8.2885-2898.2005 |
0.368 |
|
2005 |
Rayasam GV, Elbi C, Walker DA, Wolford R, Fletcher TM, Edwards DP, Hager GL. Ligand-specific dynamics of the progesterone receptor in living cells and during chromatin remodeling in vitro. Molecular and Cellular Biology. 25: 2406-18. PMID 15743833 DOI: 10.1128/Mcb.25.6.2406-2418.2005 |
0.491 |
|
2005 |
Wardell SE, Edwards DP. Mechanisms controlling agonist and antagonist potential of selective progesterone receptor modulators (SPRMs). Seminars in Reproductive Medicine. 23: 9-21. PMID 15714386 DOI: 10.1055/S-2005-864030 |
0.734 |
|
2005 |
Edwards DP. Regulation of signal transduction pathways by estrogen and progesterone. Annual Review of Physiology. 67: 335-76. PMID 15709962 DOI: 10.1146/Annurev.Physiol.67.040403.120151 |
0.48 |
|
2005 |
Narayanan R, Adigun AA, Edwards DP, Weigel NL. Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator. Molecular and Cellular Biology. 25: 264-77. PMID 15601848 DOI: 10.1128/Mcb.25.1.264-277.2005 |
0.43 |
|
2004 |
Agoulnik IU, Tong XW, Fischer DC, Körner K, Atkinson NE, Edwards DP, Headon DR, Weigel NL, Kieback DG. A germline variation in the progesterone receptor gene increases transcriptional activity and may modify ovarian cancer risk. The Journal of Clinical Endocrinology and Metabolism. 89: 6340-7. PMID 15579801 DOI: 10.1210/Jc.2004-0114 |
0.431 |
|
2004 |
Boonyaratanakornkit V, Edwards DP. Receptor mechanisms of rapid extranuclear signalling initiated by steroid hormones. Essays in Biochemistry. 40: 105-20. PMID 15242342 DOI: 10.1042/Bse0400105 |
0.508 |
|
2004 |
Goldsmith LT, Weiss G, Palejwala S, Plant TM, Wojtczuk A, Lambert WC, Ammur N, Heller D, Skurnick JH, Edwards D, Cole DM. Relaxin regulation of endometrial structure and function in the rhesus monkey Proceedings of the National Academy of Sciences of the United States of America. 101: 4685-4689. PMID 15070778 DOI: 10.1073/Pnas.0400776101 |
0.368 |
|
2004 |
Melvin VS, Harrell C, Adelman JS, Kraus WL, Churchill M, Edwards DP. The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB. The Journal of Biological Chemistry. 279: 14763-71. PMID 14739282 DOI: 10.1074/Jbc.M313335200 |
0.561 |
|
2003 |
Edwards DP, Boonyaratanakornkit V. Rapid extranuclear signaling by the estrogen receptor (ER): MNAR couples ER and Src to the MAP kinase signaling pathway. Molecular Interventions. 3: 12-5. PMID 14993433 DOI: 10.1124/Mi.3.1.12 |
0.434 |
|
2003 |
Leonhardt SA, Boonyaratanakornkit V, Edwards DP. Progesterone receptor transcription and non-transcription signaling mechanisms. Steroids. 68: 761-70. PMID 14667966 DOI: 10.1016/S0039-128X(03)00129-6 |
0.532 |
|
2003 |
Sasano H, Edwards DP, Anderson TJ, Silverberg SG, Evans DB, Santen RJ, Ramage P, Simpson ER, Bhatnagar AS, Miller WR. Validation of new aromatase monoclonal antibodies for immunohistochemistry: progress report. The Journal of Steroid Biochemistry and Molecular Biology. 86: 239-44. PMID 14623517 DOI: 10.1016/S0960-0760(03)00363-7 |
0.301 |
|
2002 |
Edwards DP, Wardell SE, Boonyaratanakornkit V. Progesterone receptor interacting coregulatory proteins and cross talk with cell signaling pathways. The Journal of Steroid Biochemistry and Molecular Biology. 83: 173-86. PMID 12650714 DOI: 10.1016/S0960-0760(02)00265-0 |
0.739 |
|
2002 |
Leonhardt SA, Edwards DP. Mechanism of action of progesterone antagonists. Experimental Biology and Medicine (Maywood, N.J.). 227: 969-80. PMID 12486206 DOI: 10.1177/153537020222701104 |
0.502 |
|
2002 |
Press M, Spaulding B, Groshen S, Kaminsky D, Hagerty M, Sherman L, Christensen K, Edwards DP. Comparison of different antibodies for detection of progesterone receptor in breast cancer. Steroids. 67: 799-813. PMID 12123792 DOI: 10.1016/S0039-128X(02)00039-9 |
0.359 |
|
2002 |
Wardell SE, Boonyaratanakornkit V, Adelman JS, Aronheim A, Edwards DP. Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator. Molecular and Cellular Biology. 22: 5451-66. PMID 12101239 DOI: 10.1128/Mcb.22.15.5451-5466.2002 |
0.74 |
|
2002 |
Melvin VS, Roemer SC, Churchill ME, Edwards DP. The C-terminal extension (CTE) of the nuclear hormone receptor DNA binding domain determines interactions and functional response to the HMGB-1/-2 co-regulatory proteins. The Journal of Biological Chemistry. 277: 25115-24. PMID 12006575 DOI: 10.1074/Jbc.M110400200 |
0.792 |
|
2002 |
Schultz JR, Loven MA, Melvin VM, Edwards DP, Nardulli AM. Differential modulation of DNA conformation by estrogen receptors alpha and beta. The Journal of Biological Chemistry. 277: 8702-7. PMID 11773069 DOI: 10.1074/Jbc.M108491200 |
0.776 |
|
2002 |
Igarashi T, Bruner-Tran K, Edwards D, Eisenberg E, Osteen K. Differential regulation of the progesterone receptor (PR) by TCDD in isolated human endometrial stromal cells versus stromal-epithelial co-cultures Fertility and Sterility. 77: S2-S3. DOI: 10.1016/S0015-0282(01)03017-5 |
0.39 |
|
2001 |
Melvin VS, Edwards DP. Expression and purification of recombinant human progesterone receptor in baculovirus and bacterial systems Methods in Molecular Biology (Clifton, N.J.). 176: 39-54. PMID 11554337 DOI: 10.1385/1-59259-115-9:39 |
0.358 |
|
2001 |
Boonyaratanakornkit V, Scott MP, Ribon V, Sherman L, Anderson SM, Maller JL, Miller WT, Edwards DP. Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases. Molecular Cell. 8: 269-80. PMID 11545730 DOI: 10.1016/S1097-2765(01)00304-5 |
0.453 |
|
2001 |
Doppler W, Windegger M, Soratroi C, Tomasi J, Lechner J, Rusconi S, Cato AC, Almlöf T, Liden J, Okret S, Gustafsson JA, Richard-Foy H, Starr DB, Klocker H, Edwards D, et al. Expression level-dependent contribution of glucocorticoid receptor domains for functional interaction with STAT5. Molecular and Cellular Biology. 21: 3266-79. PMID 11287629 DOI: 10.1128/Mcb.21.9.3266-3279.2001 |
0.503 |
|
2001 |
Knotts TA, Orkiszewski RS, Cook RG, Edwards DP, Weigel NL. Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites. The Journal of Biological Chemistry. 276: 8475-83. PMID 11110801 DOI: 10.1074/Jbc.M009805200 |
0.345 |
|
2000 |
Edwards DP. The role of coactivators and corepressors in the biology and mechanism of action of steroid hormone receptors Journal of Mammary Gland Biology and Neoplasia. 5: 307-324. PMID 14973393 DOI: 10.1023/A:1009503029176 |
0.569 |
|
2000 |
Giangrande PH, Kimbrel EA, Edwards DP, McDonnell DP. The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Molecular and Cellular Biology. 20: 3102-15. PMID 10757795 DOI: 10.1128/Mcb.20.9.3102-3115.2000 |
0.551 |
|
2000 |
Edwards DP, Leonhardt SA, Gass-Handel E. Novel mechanisms of progesterone antagonists and progesterone receptor Journal of the Society For Gynecologic Investigation. 7. PMID 10732325 DOI: 10.1016/S1071-5576(99)00061-1 |
0.54 |
|
2000 |
Clemm DL, Sherman L, Boonyaratanakornkit V, Schrader WT, Weigel NL, Edwards DP. Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody. Molecular Endocrinology (Baltimore, Md.). 14: 52-65. PMID 10628747 DOI: 10.1210/Mend.14.1.0413 |
0.391 |
|
2000 |
Nazareth LV, Stenoien DL, Bingman WE, James AJ, Wu CC, Zhang Y, Edwards DP, Mancini M, Marcelli M, Lamb DJ, Weigel NL. Erratum: A c619y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1) (Molecular Endocrinology (1999) 13 (2065-2075)) Molecular Endocrinology. 14. DOI: 10.1210/Me.14.4.544 |
0.41 |
|
2000 |
Attia GR, Zeitoun K, Edwards D, Johns A, Carr BR, Bulun SE. Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis The Journal of Clinical Endocrinology and Metabolism. 85: 2897-2902. DOI: 10.1210/Jc.85.8.2897 |
0.383 |
|
1999 |
Nazareth LV, Stenoien DL, Bingman WE, James AJ, Wu C, Zhang Y, Edwards DP, Mancini M, Marcelli M, Lamb DJ, Weigel NL. A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1) Molecular Endocrinology. 13: 2065-2075. PMID 10598582 DOI: 10.1210/Mend.13.12.0382 |
0.394 |
|
1999 |
O'Conner JL, Wade MF, Edwards DP, Mahesh VB. Progesterone and regulation of the follicle-stimulating hormone (FSH-beta) gene. Steroids. 64: 592-7. PMID 10503714 DOI: 10.1016/S0039-128X(99)00038-0 |
0.44 |
|
1999 |
Melvin VS, Edwards DP. Coregulatory proteins in steroid hormone receptor action: The role of chromatin high mobility group proteins HMG-1 and -2 Steroids. 64: 576-586. PMID 10503712 DOI: 10.1016/S0039-128X(99)00036-7 |
0.565 |
|
1999 |
Tetel MJ, Giangrande PH, Leonhardt SA, McDonnell DP, Edwards DP. Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo. Molecular Endocrinology (Baltimore, Md.). 13: 910-24. PMID 10379890 DOI: 10.1210/Mend.13.6.0300 |
0.724 |
|
1999 |
Vázquez F, Rodríguez-Manzaneque JC, Lydon JP, Edwards DP, O'Malley BW, Iruela-Arispe ML. Progesterone regulates proliferation of endothelial cells. The Journal of Biological Chemistry. 274: 2185-92. PMID 9890981 DOI: 10.1074/Jbc.274.4.2185 |
0.408 |
|
1998 |
Plisov SY, Poirot ME, Modarress KJ, Cavanaugh AH, Edwards DP, Simons SS. Different populations of progesterone receptor-steroid complexes in binding to specific DNA sequences: Effects of salts on kinetics and specificity Journal of Steroid Biochemistry and Molecular Biology. 67: 251-266. PMID 9879984 DOI: 10.1016/S0960-0760(98)00118-6 |
0.475 |
|
1998 |
Leonhardt SA, Altmann M, Edwards DP. Agonist and antagonists induce homodimerization and mixed ligand heterodimerization of human progesterone receptors in vivo by a mammalian two-hybrid assay Molecular Endocrinology. 12: 1914-1930. PMID 9849965 DOI: 10.1210/Mend.12.12.0210 |
0.521 |
|
1998 |
Boonyaratanakornkit V, Melvin V, Prendergast P, Altmann M, Ronfani L, Bianchi ME, Taraseviciene L, Nordeen SK, Allegretto EA, Edwards DP. High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells. Molecular and Cellular Biology. 18: 4471-87. PMID 9671457 DOI: 10.1128/Mcb.18.8.4471 |
0.802 |
|
1998 |
Romine LE, Wood JR, Lamia LA, Prendergast P, Edwards DP, Nardulli AM. The high mobility group protein 1 enhances binding of the estrogen receptor DNA binding domain to the estrogen response element Molecular Endocrinology. 12: 664-674. PMID 9605929 DOI: 10.1210/Mend.12.5.0111 |
0.536 |
|
1998 |
Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. The Journal of Biological Chemistry. 273: 12101-8. PMID 9575154 DOI: 10.1074/Jbc.273.20.12101 |
0.53 |
|
1998 |
Gass EK, Leonhardt SA, Nordeen SK, Edwards DP. The antagonists RU486 and ZK98299 stimulate progesterone receptor binding to deoxyribonucleic acid in vitro and in vivo, but have distinct effects on receptor conformation Endocrinology. 139: 1905-1919. PMID 9528977 DOI: 10.1210/Endo.139.4.5944 |
0.541 |
|
1998 |
Edwards DP. Coregulatory Proteins in Nuclear Hormone Receptor Action Vitamins and Hormones. 55: 165-218. DOI: 10.1016/S0083-6729(08)60936-X |
0.537 |
|
1997 |
O'Conner JL, Wade MF, Prendergast P, Edwards DP, Boonyaratanakornkit V, Mahesh VB. A 361 base pair region of the rat FSH-beta promoter contains multiple progesterone receptor-binding sequences and confers progesterone responsiveness. Molecular and Cellular Endocrinology. 136: 67-78. PMID 9510069 DOI: 10.1016/S0303-7207(97)00216-5 |
0.41 |
|
1997 |
Moore MR, Zhou JL, Blankenship KA, Strobl JS, Edwards DP, Gentry RN. A sequence in the 5' flanking region confers progestin responsiveness on the human c-myc gene. The Journal of Steroid Biochemistry and Molecular Biology. 62: 243-52. PMID 9408078 DOI: 10.1016/S0960-0760(97)00036-8 |
0.406 |
|
1997 |
Tetel MJ, Jung S, Carbajo P, Ladtkow T, Skafar DF, Edwards DP. Hinge and amino-terminal sequences contribute to solution dimerization of human progesterone receptor. Molecular Endocrinology (Baltimore, Md.). 11: 1114-28. PMID 9212059 DOI: 10.1210/Mend.11.8.9963 |
0.746 |
|
1997 |
Zhang Y, Beck CA, Poletti A, Clement JP, Prendergast P, Yip TT, Hutchens TW, Edwards DP, Weigel NL. Phosphorylation of human progesterone receptor by cyclin-dependent kinase 2 on three sites that are authentic basal phosphorylation sites in vivo. Molecular Endocrinology (Baltimore, Md.). 11: 823-32. PMID 9171245 DOI: 10.1210/Mend.11.6.0006 |
0.333 |
|
1996 |
Kepa JK, Jacobsen BM, Boen EA, Prendergast P, Edwards DP, Takimoto G, Wierman ME. Direct binding of progesterone receptor to nonconsensus DNA sequences represses rat GnRH. Molecular and Cellular Endocrinology. 117: 27-39. PMID 8734471 DOI: 10.1016/0303-7207(95)03723-3 |
0.471 |
|
1996 |
Sabeur K, Edwards DP, Meizel S. Human sperm plasma membrane progesterone receptor(s) and the acrosome reaction Biology of Reproduction. 54: 993-1001. PMID 8722618 DOI: 10.1095/Biolreprod54.5.993 |
0.394 |
|
1996 |
Prendergast P, Pan Z, Edwards DP. Progesterone receptor-induced bending of its target DNA: Distinct effects of the A and B receptor forms Molecular Endocrinology. 10: 393-407. PMID 8721984 DOI: 10.1210/Mend.10.4.8721984 |
0.485 |
|
1996 |
Wagner BL, Pollio G, Leonhardt S, Wani MC, Lee DY, Imhof MO, Edwards DP, Cook CE, McDonnell DP. 16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity. Proceedings of the National Academy of Sciences of the United States of America. 93: 8739-44. PMID 8710941 DOI: 10.1073/Pnas.93.16.8739 |
0.481 |
|
1996 |
Beck CA, Zhang Y, Altmann M, Weigel NL, Edwards DP. Stoichiometry and site-specific phosphorylation of human progesterone receptor in native target cells and in the baculovirus expression system. The Journal of Biological Chemistry. 271: 19546-55. PMID 8702648 DOI: 10.1074/Jbc.271.32.19546 |
0.398 |
|
1996 |
Carbajo P, Christensen K, Edwards DP, Skafar DF. Binding of [3H]progesterone to the human progesterone receptor: Differences between individual and mixed isoforms Endocrinology. 137: 2339-2346. PMID 8641184 DOI: 10.1210/Endo.137.6.8641184 |
0.393 |
|
1996 |
Beck CA, Zhang Y, Weigel NL, Edwards DP. Two types of anti-progestins have distinct effects on site-specific phosphorylation of human progesterone receptor. The Journal of Biological Chemistry. 271: 1209-17. PMID 8557652 DOI: 10.1074/Jbc.271.2.1209 |
0.379 |
|
1995 |
Webster JC, Pedersen NR, Edwards DP, Beck CA, Miller WL. The 5'-flanking region of the ovine follicle-stimulating hormone-beta gene contains six progesterone response elements: three proximal elements are sufficient to increase transcription in the presence of progesterone. Endocrinology. 136: 1049-58. PMID 7867558 DOI: 10.1210/Endo.136.3.7867558 |
0.436 |
|
1995 |
Nordeen SK, Bona BJ, Beck CA, Edwards DP, Borror KC, DeFranco DB. The two faces of a steroid antagonist: when an antagonist isn't. Steroids. 60: 97-104. PMID 7792825 DOI: 10.1016/0039-128X(94)00001-S |
0.492 |
|
1995 |
Weigel NL, Bai W, Zhang Y, Beck CA, Edwards DP, Poletti A. Phosphorylation and progesterone receptor function. The Journal of Steroid Biochemistry and Molecular Biology. 53: 509-14. PMID 7626502 DOI: 10.1016/0960-0760(95)00098-K |
0.46 |
|
1995 |
Edwards DP, Altmann M, DeMarzo A, Zhang Y, Weigel NL, Beck CA. Progesterone receptor and the mechanism of action of progesterone antagonists. The Journal of Steroid Biochemistry and Molecular Biology. 53: 449-58. PMID 7626494 DOI: 10.1016/0960-0760(95)00091-D |
0.463 |
|
1995 |
Zhang Y, Beck CA, Poletti A, Edwards DP, Weigel NL. Identification of a group of Ser-Pro motif hormone-inducible phosphorylation sites in the human progesterone receptor. Molecular Endocrinology (Baltimore, Md.). 9: 1029-40. PMID 7476977 DOI: 10.1210/Mend.9.8.7476977 |
0.456 |
|
1995 |
Milad M, Sullivan W, Diehl E, Altmann M, Nordeen S, Edwards DP, Toft DO. Interaction of the progesterone receptor with binding proteins for FK506 and cyclosporin A. Molecular Endocrinology (Baltimore, Md.). 9: 838-47. PMID 7476967 DOI: 10.1210/Mend.9.7.7476967 |
0.448 |
|
1994 |
Oñate SA, Prendergast P, Wagner JP, Nissen M, Reeves R, Pettijohn DE, Edwards DP. The DNA-bending protein HMG-1 enhances progesterone receptor binding to its target DNA sequences. Molecular and Cellular Biology. 14: 3376-91. PMID 8164686 DOI: 10.1128/Mcb.14.5.3376 |
0.5 |
|
1994 |
Prendergast P, Oñate SA, Christense K, Edwards DP. Nuclear accessory factors enhance the binding of progesterone receptor to specific target DNA Journal of Steroid Biochemistry and Molecular Biology. 48: 1-13. PMID 8136295 DOI: 10.1016/0960-0760(94)90245-3 |
0.492 |
|
1993 |
Beck CA, Weigel NL, Moyer ML, Nordeen SK, Edwards DP. The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways Proceedings of the National Academy of Sciences of the United States of America. 90: 4441-4445. PMID 8389450 DOI: 10.1073/Pnas.90.10.4441 |
0.479 |
|
1993 |
Lieberman BA, Bona BJ, Edwards DP, Nordeen SK. The constitution of a progesterone response element Molecular Endocrinology. 7: 515-527. PMID 8388996 DOI: 10.1210/Mend.7.4.8388996 |
0.496 |
|
1993 |
Beck CA, Estes PA, Bona BJ, Muro-Cacho CA, Nordeen SK, Edwards DP. The steroid antagonist RU486 exerts different effects on the glucocorticoid and progesterone receptors. Endocrinology. 133: 728-40. PMID 8344212 DOI: 10.1210/Endo.133.2.8344212 |
0.466 |
|
1993 |
Edwards DP, Weigel NL, Nordeen SK, Beck CA. Modulators of cellular protein phosphorylation alter the trans-activation function of human progesterone receptor and the biological activity of progesterone antagonists Breast Cancer Research and Treatment. 27: 41-56. PMID 8260729 DOI: 10.1007/Bf00683192 |
0.508 |
|
1992 |
Weigel NL, Beck CA, Estes PA, Prendergast P, Altmann M, Christensen K, Edwards DP. Ligands induce conformational changes in the carboxyl-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody. Molecular Endocrinology (Baltimore, Md.). 6: 1585-97. PMID 1448113 DOI: 10.1210/Mend.6.10.1448113 |
0.394 |
|
1992 |
Demarzo AM, Oñate SA, Nordeen SK, Edwards DP. Effects of the steroid antagonist RU486 on dimerization of the human progesterone receptor Biochemistry. 31: 10491-10501. PMID 1420166 DOI: 10.1021/Bi00158A012 |
0.484 |
|
1992 |
Beck CA, Edwards DP. Progesterone receptors in breast cancer Cancer Treatment and Research. 61: 317-352. PMID 1360240 DOI: 10.1007/978-1-4615-3500-3_16 |
0.557 |
|
1992 |
Beck CA, Weigel NL, Edwards DP. Effects of hormone and cellular modulators of protein phosphorylation on transcriptional activity, DNA binding, and phosphorylation of human progesterone receptors Molecular Endocrinology. 6: 607-620. PMID 1316549 DOI: 10.1210/Mend.6.4.1316549 |
0.48 |
|
1992 |
Edwards DP, Estes PA, Fadok VA, Bona BJ, Oñate S, Nordeen SK, Welch WJ. Heat shock alters the composition of heteromeric steroid receptor complexes and enhances receptor activity in vivo. Biochemistry. 31: 2482-91. PMID 1312348 DOI: 10.1021/Bi00124A007 |
0.395 |
|
1991 |
Demarzo AM, Beck CA, Oñate SA, Edwards DP. Dimerization of mammalian progesterone receptors occurs in the absence of DNA and is related to the release of the 90-kDa heat shock protein Proceedings of the National Academy of Sciences of the United States of America. 88: 72-76. PMID 1986383 DOI: 10.1073/Pnas.88.1.72 |
0.504 |
|
1991 |
Oñate SA, Estes PA, Welch WJ, Nordeen SK, Edwards DP. Evidence that heat shock protein-70 associated with progesterone receptors is not involved in receptor-DNA binding. Molecular Endocrinology (Baltimore, Md.). 5: 1993-2004. PMID 1791844 DOI: 10.1210/Mend-5-12-1993 |
0.46 |
|
1991 |
Christensen K, Estes PA, Oñate SA, Beck CA, DeMarzo A, Altmann M, Lieberman BA, St John J, Nordeen SK, Edwards DP. Characterization and functional properties of the A and B forms of human progesterone receptors synthesized in a baculovirus system. Molecular Endocrinology (Baltimore, Md.). 5: 1755-70. PMID 1779977 DOI: 10.1210/Mend-5-11-1755 |
0.481 |
|
1991 |
Edwards DP, DeMarzo AM, Oñate SA, Beck CA, Estes PA, Nordeen SK. Mechanisms controlling steroid receptor binding to specific DNA sequences. Steroids. 56: 271-8. PMID 1652169 DOI: 10.1016/0039-128X(91)90046-X |
0.538 |
|
1989 |
Bagchi MK, Elliston JF, Tsai SY, Edwards DP, Tsai MJ, O'Malley BW. Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element. Molecular Endocrinology (Baltimore, Md.). 2: 1221-9. PMID 3216861 DOI: 10.1210/Mend-2-12-1221 |
0.489 |
|
1989 |
El-Ashry D, Onate SA, Nordeen SK, Edwards DP. Human progesterone receptor complexed with the antagonist RU 486 binds to hormone response elements in a structurally altered form Molecular Endocrinology. 3: 1545-1558. PMID 2608048 DOI: 10.1210/Mend-3-10-1545 |
0.551 |
|
1989 |
Kuhnel B, El-Ashry D, Edwards DP, Nordeen SK. Mapping contacts between unpurified human progesterone receptor and the hormone response element of mouse mammary tumor virus Dna. 8: 703-713. PMID 2558865 |
0.415 |
|
1989 |
Nordeen SK, Kühnel B, Lawler-Heavner J, Barber DA, Edwards DP. A quantitative comparison of dual control of a hormone response element by progestins and glucocorticoids in the same cell line. Molecular Endocrinology (Baltimore, Md.). 3: 1270-8. PMID 2550815 DOI: 10.1210/Mend-3-8-1270 |
0.469 |
|
1989 |
Edwards DP, Kühnel B, Estes PA, Nordeen SK. Human progesterone receptor binding to mouse mammary tumor virus deoxyribonucleic acid: dependence on hormone and nonreceptor nuclear factor(s). Molecular Endocrinology (Baltimore, Md.). 3: 381-91. PMID 2540430 DOI: 10.1210/Mend-3-2-381 |
0.544 |
|
1988 |
Elashry-Stowers D, Zava DT, Speers WC, Edwards DP. Immunocytochemical Localization of Progesterone Receptors in Breast Cancer with Anti-Human Receptor Monoclonal Antibodies Cancer Research. 48: 6462-6474. PMID 3180062 |
0.331 |
|
1988 |
Krett NL, Edwards DP, Horwitz KB. Chapter 14 Progesterone action and receptors New Comprehensive Biochemistry. 18: 241-267. DOI: 10.1016/S0167-7306(08)60649-3 |
0.498 |
|
1987 |
Wei LL, Sheridan PL, Krett NL, Francis MD, Toft DO, Edwards DP, Horwitz KB. Immunologic analysis of human breast cancer progesterone receptors. 2. Structure, phosphorylation, and processing. Biochemistry. 26: 6262-72. PMID 3689774 DOI: 10.1021/Bi00393A046 |
0.456 |
|
1987 |
Estes PA, Suba EJ, Lawler-Heavner J, Elashry-Stowers D, Wei LL, Toft DO, Sullivan WP, Horwitz KB, Edwards DP. Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies. Biochemistry. 26: 6250-62. PMID 3689773 DOI: 10.1021/Bi00393A045 |
0.454 |
|
1985 |
Ciocca DR, Puy LA, Edwards DP, Adams DJ, McGuire WL. The presence of an estrogen-regulated protein detected by monoclonal antibody in abnormal human endometrium Journal of Clinical Endocrinology and Metabolism. 60: 137-143. PMID 3880561 DOI: 10.1210/Jcem-60-1-137 |
0.328 |
|
1984 |
Zarucki-Schulz T, Kulomaa MS, Headon DR, Weigel NL, Baez M, Edwards DP, McGuire WL, Schrader WT, O'Malley BW. Molecular cloning of a cDNA for the chicken progesterone receptor B antigen. Proceedings of the National Academy of Sciences of the United States of America. 81: 6358-62. PMID 6593705 DOI: 10.1073/Pnas.81.20.6358 |
0.373 |
|
1984 |
Ciocca DR, Adams DJ, Edwards DP, Bjercke RJ, McGuire WL. Estrogen-induced 24K protein in MCF-7 breast cancer cells is localized in granules Breast Cancer Research and Treatment. 4: 261-268. PMID 6518292 DOI: 10.1007/Bf01806037 |
0.34 |
|
1984 |
McGuire WL, Adams DJ, Edwards DP. Estrogen-regulated protein in human breast cancer Journal of Steroid Biochemistry. 20: 73-75. PMID 6368988 DOI: 10.1016/0022-4731(84)90191-2 |
0.332 |
|
1984 |
Edwards DP, Weigel NL, Schrader WT, O'Malley BW, McGuire WL. Structural analysis of chicken oviduct progesterone receptor using monoclonal antibodies to the subunit B protein. Biochemistry. 23: 4427-35. PMID 6207857 DOI: 10.1021/Bi00314A029 |
0.391 |
|
1984 |
Edwards D, McGuire W, Weigel N, Schrader W, O'Malley B. A monoclonal antibody produced against the chicken oviduct progesterone receptor shows cross reaction with human antigen Journal of Steroid Biochemistry. 20: 1627. DOI: 10.1016/0022-4731(84)90937-3 |
0.305 |
|
1983 |
Adams DJ, Hajj H, Bitar KG, Edwards DP, McGuire WL. Purification of an estrogen-regulated breast cancer protein by monoclonal antibody affinity chromatography Endocrinology. 113: 415-417. PMID 6861712 DOI: 10.1210/Endo-113-1-415 |
0.335 |
|
1983 |
McGuire W, Edwards D, Adams D. 341 Characterization of a 24K estrogen regulated protein in human breast cancer cells Journal of Steroid Biochemistry. 19: 114. DOI: 10.1016/0022-4731(83)91841-1 |
0.338 |
|
1981 |
Edwards DP, Adams DJ, McGuire WL. Estradiol stimulates synthesis of a major intracellular protein in a human breast cancer cell line (MCF-7) Breast Cancer Research and Treatment. 1: 209-223. PMID 7348573 DOI: 10.1007/Bf01806261 |
0.388 |
|
1981 |
Edwards DP, Adams DJ, McGuire WL. Estrogen regulation of growth and specific protein synthesis in human breast cancer cells in tissue culture Advances in Experimental Medicine and Biology. 138: 133-149. PMID 7342712 DOI: 10.1007/978-1-4615-7192-6_8 |
0.392 |
|
1981 |
Edwards DP, Adams DJ, McGuire WL. Specific protein synthesis regulated by estrogen in human breast cancer Journal of Steroid Biochemistry. 15: 247-259. PMID 7339251 DOI: 10.1016/0022-4731(81)90281-8 |
0.376 |
|
1980 |
Edwards DP, McGuire WL. 17α-Estradiol is a biologically active estrogen in human breast cancer cells in tissue culture Endocrinology. 107: 884-891. PMID 7408775 DOI: 10.1210/Endo-107-4-884 |
0.417 |
|
1980 |
Edwards DP, Adams DJ, Savage N, McGuire WL. Estrogen induced synthesis of specific proteins in human breast cancer cells Biochemical and Biophysical Research Communications. 93: 804-812. PMID 7387677 DOI: 10.1016/0006-291X(80)91148-1 |
0.376 |
|
1980 |
Edwards DP, Martin PM, Horwitz KB, Chamness GC, McGuire WL. Subcellular compartmentalization of estrogen receptors in human breast cancer cells. Experimental Cell Research. 127: 197-213. PMID 7379864 DOI: 10.1016/0014-4827(80)90427-9 |
0.491 |
|
1980 |
Edwards DP, Murthy SR, McGuire WL. Effects of Estrogen and Antiestrogen on DNA Polymerase in Human Breast Cancer Cancer Research. 40: 1722-1726. PMID 7371001 |
0.325 |
|
1980 |
Adams DJ, Edwards DP, McGuire WL. Estrogen regulation of specific messinger RNA's in human breast cancer cells Biochemical and Biophysical Research Communications. 97: 1354-1361. PMID 7213361 DOI: 10.1016/S0006-291X(80)80016-7 |
0.385 |
|
1979 |
Edwards DP, Chamness GC, McGuire WL. Estrogen and progesterone receptor proteins in breast cancer Bba - Reviews On Cancer. 560: 457-486. PMID 391286 DOI: 10.1016/0304-419X(79)90013-1 |
0.446 |
|
1977 |
Edwards DP, Bransome ED, O'Conner JL, Braselton WE. Inhibition of human placental progesterone synthesis by estranes: a novel relationship of structure to activity. Journal of Steroid Biochemistry. 8: 1011-5. PMID 916672 DOI: 10.1016/0022-4731(77)90200-X |
0.307 |
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