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John R. Murphy, PhD - Publications

Affiliations: 
1984 Microbiology and Molecular Genetics Harvard Medical School, Boston, MA, United States 
 1984- Microbiology Boston University School of Medicine, Boston, MA 
Area:
molecular biology and molecular genetics of bacterial protein toxins
Website:
http://www.bu.edu/neidl/research/researchers/john-r-murphy-ph-d/
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Parveen S, Shen J, Lun S, Zhao L, Alt J, Koleske B, Leone RD, Rais R, Powell JD, Murphy JR, Slusher BS, Bishai WR. Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis. Nature Communications. 14: 7427. PMID 37973991 DOI: 10.1038/s41467-023-43304-0  0.593
2023 Parveen S, Shen J, Lun S, Zhao L, Koleske B, Leone RD, Rais R, Powell JD, Murphy JR, Slusher BS, Bishai WR. Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against . Biorxiv : the Preprint Server For Biology. PMID 36865287 DOI: 10.1101/2023.02.23.529704  0.586
2021 Parveen S, Lun S, Urbanowski ME, Cardin M, Shen J, Murphy JR, Bishai WR. Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells and related cells using a diphtheria toxin-based fusion protein. The Journal of Infectious Diseases. PMID 33955457 DOI: 10.1093/infdis/jiab235  0.611
2021 Parveen S, Siddharth S, Cheung LS, Kumar A, Shen J, Murphy JR, Sharma D, Bishai WR. Therapeutic targeting with DABIL-4 depletes myeloid suppressor cells in 4T1 triple-negative breast cancer model. Molecular Oncology. PMID 33682324 DOI: 10.1002/1878-0261.12938  0.593
2019 Kumar P, Kumar A, Parveen S, Murphy JR, Bishai W. Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy. Immunotherapy. PMID 31361167 DOI: 10.2217/Imt-2019-0060  0.661
2019 Parveen S, Bishai WR, Murphy JR. : Diphtheria Toxin, the Operon, and Its Regulation by Fe2 Activation of apo-DtxR. Microbiology Spectrum. 7. PMID 31267892 DOI: 10.1128/Microbiolspec.Gpp3-0063-2019  0.632
2019 Cheung LS, Fu J, Kumar P, Kumar A, Urbanowski ME, Ihms EA, Parveen S, Bullen CK, Patrick GJ, Harrison R, Murphy JR, Pardoll DM, Bishai WR. Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718426 DOI: 10.1073/Pnas.1815087116  0.661
2017 Gupta S, Cheung L, Pokkali S, Winglee K, Guo H, Murphy JR, Bishai WR. Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis. The Journal of Infectious Diseases. 215: 1883-1887. PMID 28863467 DOI: 10.1093/Infdis/Jix208  0.608
2003 Ando M, Manabe YC, Converse PJ, Miyazaki E, Harrison R, Murphy JR, Bishai WR. Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus. Infection and Immunity. 71: 2584-90. PMID 12704132 DOI: 10.1128/Iai.71.5.2584-2590.2003  0.558
2002 Brennan PJ, Terwilliger T, Barry CE, Manca C, Su H, Reed M, Rutter K, Domenech P, Kaplan G, Li YJ, Wagner D, Bermudez LE, Bodnar K, Flynn J, Campos-Neto A, ... ... Murphy JR, et al. The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135. PMID 12408170 DOI: 10.1054/Tube.2002.0329  0.526
1999 Manabe YC, Saviola BJ, Sun L, Murphy JR, Bishai WR. Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12844-8. PMID 10536010 DOI: 10.1073/Pnas.96.22.12844  0.573
1989 Williams DP, Parker K, Bacha P, Bishai W, Borowski M, Genbauffe F, Strom TB, Murphy JR. Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein. Protein Engineering. 1: 493-8. PMID 3334101 DOI: 10.1093/protein/1.6.493  0.587
1987 Bishai WR, Miyanohara A, Murphy JR. Cloning and expression in Escherichia coli of three fragments of diphtheria toxin truncated within fragment B. Journal of Bacteriology. 169: 1554-63. PMID 3549695  0.592
1987 Bishai WR, Rappuoli R, Murphy JR. High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coli. Journal of Bacteriology. 169: 5140-51. PMID 3312166  0.574
1986 Murphy JR, Bishai W, Borowski M, Miyanohara A, Boyd J, Nagle S. Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 83: 8258-62. PMID 3095831 DOI: 10.1073/pnas.83.21.8258  0.548
1974 Murphy JR, Girard AE, Tilton RC. Ultrastructure of a marine Thiobacillus. Journal of General Microbiology. 85: 130-8. PMID 4373524 DOI: 10.1099/00221287-85-1-130  0.461
1972 Murphy JR, Frankenfeld J, Calvert J, Tilton RC. Demonstration of rhodanese activity in polyacrylamide gels. Applied Microbiology. 24: 283-5. PMID 16349929  0.497
1972 Tilton RC, Murphy JR, Mallett E. Assay for gentamicin. The New England Journal of Medicine. 287: 1100. PMID 4562443  0.487
1971 Tilton RC, Murphy JR, van Soestbergen A. Erwinia species from human sources. American Journal of Clinical Pathology. 56: 187-92. PMID 5567724  0.467
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