| Year |
Citation |
Score |
| 2024 |
Jung W, Abdelnour A, Kaplonek P, Herrero R, Shih-Lu Lee J, Barbati DR, Chicz TM, Levine KS, Fantin RC, Loria V, Porras C, Lauffenburger DA, Gail MH, Aparicio A, Hildesheim A, ... Alter G, et al. SARS-CoV-2 infection prior to vaccination amplifies Fc-mediated humoral profiles in an age-dependent manner. Cell Reports. 43: 114684. PMID 39213155 DOI: 10.1016/j.celrep.2024.114684 |
0.349 |
|
| 2024 |
Ilinykh PA, Huang K, Gunn BM, Kuzmina NA, Kedarinath K, Jurado-Cobena E, Zhou F, Subramani C, Hyde MA, Velazquez JV, Williamson LE, Gilchuk P, Carnahan RH, Alter G, Crowe JE, et al. Antibodies targeting the glycan cap of Ebola virus glycoprotein are potent inducers of the complement. Communications Biology. 7: 871. PMID 39020082 DOI: 10.1038/s42003-024-06556-0 |
0.349 |
|
| 2024 |
Dias AG, Duarte E, Zambrana JV, Cardona-Ospina JA, Bos S, Roy V, Kuan G, Balmaseda A, Alter G, Harris E. Complement-dependent virion lysis mediated by dengue-Zika virus cross-reactive antibodies correlates with protection from severe dengue disease. Medrxiv : the Preprint Server For Health Sciences. PMID 38883768 DOI: 10.1101/2024.06.03.24308395 |
0.352 |
|
| 2024 |
Bebell LM, Ngonzi J, Butler A, Kumbakumba E, Adong J, Loos C, Boatin AA, Bassett IV, Siedner MJ, Williams PL, Mattie H, Hedt-Gauthier B, Correia KFB, Lake E, Alter G. Distinct cytokine profiles in late pregnancy in Ugandan people with HIV. Scientific Reports. 14: 10980. PMID 38744864 DOI: 10.1038/s41598-024-61764-2 |
0.336 |
|
| 2024 |
Bukreyev A, Meyer M, Gunn B, Pietzsch C, Subramani C, Saphire E, Crowe J, Alter G, Himansu S, Carfi A. Divergent antibody recognition profiles are generated by protective mRNA vaccines against Marburg and Ravn viruses. Research Square. PMID 38585993 DOI: 10.21203/rs.3.rs-4087897/v1 |
0.317 |
|
| 2024 |
Spatola M, Nziza N, Irvine EB, Cizmeci D, Jung W, Van LH, Nhat LTH, Ha VTN, Phu NH, Nghia HDT, Thwaites G, Lauffenburger DA, Fortune S, Thuong NTT, Alter G. Distinctive antibody responses to Mycobacterium tuberculosis in pulmonary and brain infection. Brain : a Journal of Neurology. PMID 38442687 DOI: 10.1093/brain/awae066 |
0.333 |
|
| 2024 |
Lenart K, Arcoverde Cerveira R, Hellgren F, Ols S, Sheward DJ, Kim C, Cagigi A, Gagne M, Davis B, Germosen D, Roy V, Alter G, Letscher H, Van Wassenhove J, Gros W, et al. Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2. Npj Vaccines. 9: 17. PMID 38245545 DOI: 10.1038/s41541-024-00806-2 |
0.371 |
|
| 2024 |
Jongo S, Church LWP, Milando F, Qassim M, Schindler T, Rashid M, Tumbo A, Nyaulingo G, Bakari BM, Athuman Mbaga T, Mohamed L, Kassimu K, Simon BS, Mpina M, Zaidi I, ... ... Alter G, et al. Safety and protective efficacy of PfSPZ vaccine administered to HIV negative and positive Tanzanian adults. The Journal of Clinical Investigation. PMID 38194272 DOI: 10.1172/JCI169060 |
0.359 |
|
| 2023 |
Bartsch YC, Cizmeci D, Yuan D, Mehta N, Tolboom J, De Paepe E, van Heesbeen R, Sadoff J, Comeaux CA, Heijnen E, Callendret B, Alter G, Bastian AR. Vaccine-induced antibody Fc-effector functions in humans immunized with a combination Ad26.RSV.preF/RSV preF protein vaccine. Journal of Virology. e0077123. PMID 37902399 DOI: 10.1128/jvi.00771-23 |
0.326 |
|
| 2023 |
Ronk AJ, Lloyd NM, Zhang M, Atyeo C, Perrett HR, Mire CE, Hastie KM, Sanders RW, Brouwer PJM, Saphire EO, Ward AB, Ksiazek TG, Alvarez Moreno JC, Thaker HM, Alter G, et al. A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection. Nature Communications. 14: 5603. PMID 37699929 DOI: 10.1038/s41467-023-41376-6 |
0.332 |
|
| 2023 |
Herman JD, Atyeo C, Zur Y, Cook CE, Patel NJ, Vanni KM, Kowalski EN, Qian G, Srivatsan S, Shadick NA, Rao DA, Kellman B, Mann CJ, Lauffenburger D, Wallace ZS, ... ... Alter G, et al. Humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases. Science Translational Medicine. 15: eadf6598. PMID 37672567 DOI: 10.1126/scitranslmed.adf6598 |
0.364 |
|
| 2023 |
Jelinski J, Kowatsch MM, Lafrance MA, Berger A, Pedersen J, Azizi H, Li Y, Scholte F, Gomez A, Hollett N, Le T, Wade M, Fausther-Bovendo H, de La Vega MA, Babuadze G, ... ... Alter G, et al. Rhesus Macaques Show Increased Resistance To Repeated SHIV Intrarectal Exposure Following A Heterologous Regimen Of rVSV Vector Vaccine Expressing HIV Antigen. Emerging Microbes & Infections. 2251595. PMID 37649434 DOI: 10.1080/22221751.2023.2251595 |
0.448 |
|
| 2023 |
Boudreau CM, Burke JS, Yousif AS, Sangesland M, Jastrzebski S, Verschoor C, Kuchel G, Lingwood D, Kleanthous H, De Bruijn I, Landolfi V, Sridhar S, Alter G. Antibody-mediated NK cell activation as a correlate of immunity against influenza infection. Nature Communications. 14: 5170. PMID 37620306 DOI: 10.1038/s41467-023-40699-8 |
0.382 |
|
| 2023 |
Keitany GJ, Rubin BER, Garrett ME, Musa A, Tracy J, Liang Y, Ebert P, Moore AJ, Guan J, Eggers E, Lescano N, Brown R, Carbo A, Al-Asadi H, Ching T, ... ... Alter G, et al. Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells. Cell Chemical Biology. PMID 37586370 DOI: 10.1016/j.chembiol.2023.07.011 |
0.303 |
|
| 2023 |
Irvine EB, Darrah PA, Wang S, Wang C, McNamara RP, Roederer M, Seder RA, Lauffenburger DA, Flynn JL, Fortune SM, Alter G. Humoral correlates of protection against following intravenous Bacille Calmette-Guérin vaccination in rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 37577655 DOI: 10.1101/2023.07.31.551245 |
0.333 |
|
| 2023 |
McNamara RP, Maron JS, Boucau J, Roy V, Webb NE, Bertera HL, Barczak AK, Positives Study Staff T, Franko N, Logue JK, Kemp M, Li JZ, Zhou L, Hsieh CL, McLellan JS, ... ... Alter G, et al. Anamnestic humoral correlates of immunity across SARS-CoV-2 variants of concern. Mbio. e0090223. PMID 37535402 DOI: 10.1128/mbio.00902-23 |
0.396 |
|
| 2023 |
Muir R, Metcalf T, Fourati S, Bartsch Y, Kyosiimire-Lugemwa J, Canderan G, Alter G, Muyanja E, Okech B, Namatovu T, Namara I, Namuniina A, Ssetaala A, Mpendo J, Nanvubya A, et al. Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses. Plos Neglected Tropical Diseases. 17: e0011089. PMID 37406029 DOI: 10.1371/journal.pntd.0011089 |
0.307 |
|
| 2023 |
Kaplonek P, Cizmeci D, Kwatra G, Izu A, Lee JS, Bertera HL, Fischinger S, Mann C, Amanat F, Wang W, Koen AL, Fairlie L, Cutland CL, Ahmed K, Dheda K, ... ... Alter G, et al. ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19. Nature Immunology. PMID 37322179 DOI: 10.1038/s41590-023-01513-1 |
0.35 |
|
| 2023 |
Darrah PA, Zeppa JJ, Wang C, Irvine EB, Bucsan AN, Rodgers MA, Pokkali S, Hackney JA, Kamath M, White AG, Borish HJ, Frye LJ, Tomko J, Kracinovsky K, Lin PL, ... ... Alter G, et al. Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques. Cell Host & Microbe. PMID 37267955 DOI: 10.1016/j.chom.2023.05.006 |
0.316 |
|
| 2023 |
Wuo MG, Dugan AE, Halim M, Hauser BM, Feldman J, Caradonna TM, Zhang S, Pepi LE, Atyeo C, Fischinger S, Alter G, Garcia-Beltran WF, Azadi P, Hung D, Schmidt AG, et al. Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV-2. Acs Central Science. 9: 947-956. PMID 37252360 DOI: 10.1021/acscentsci.2c01471 |
0.328 |
|
| 2023 |
Fox JM, Roy V, Gunn BM, Bolton GR, Fremont DH, Alter G, Diamond MS, Boesch AW. Enhancing the therapeutic activity of hyperimmune IgG against chikungunya virus using FcγRIIIa affinity chromatography. Frontiers in Immunology. 14: 1153108. PMID 37251375 DOI: 10.3389/fimmu.2023.1153108 |
0.345 |
|
| 2023 |
Nziza N, Jung W, Mendu M, Chen T, McNamara RP, Fortune SM, Franken KLMC, Ottenhoff THM, Bryson B, Ngonzi J, Bebell LM, Alter G. Maternal HIV infection drives altered placental -specific antibody transfer. Frontiers in Microbiology. 14: 1171990. PMID 37228375 DOI: 10.3389/fmicb.2023.1171990 |
0.411 |
|
| 2023 |
Bernshtein B, Kelly M, Cizmeci D, Zhiteneva JA, Macvicar R, Kamruzzaman M, Bhuiyan TR, Chowdhury F, Khan AI, Qadri F, Charles RC, Xu P, Kováč P, Kaminski RW, Alter G, et al. Shigella O-specific polysaccharide functional IgA responses mediate protection against shigella infection in an endemic high-burden setting. Biorxiv : the Preprint Server For Biology. PMID 37205407 DOI: 10.1101/2023.05.04.539451 |
0.368 |
|
| 2023 |
Routhu NK, Stampfer SD, Lai L, Akhtar A, Tong X, Yuan D, Chicz TM, McNamara RP, Jakkala K, Davis-Gardner ME, St Pierre EL, Smith B, Green KM, Golden N, Picou B, ... ... Alter G, et al. Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in non-human primates. Science Immunology. eadg7015. PMID 37191508 DOI: 10.1126/sciimmunol.adg7015 |
0.328 |
|
| 2023 |
Spatola M, Nziza N, Jung W, Deng Y, Yuan D, Dinoto A, Bozzetti S, Chiodega V, Ferrari S, Lauffenburger DA, Mariotto S, Alter G. Neurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses. Brain : a Journal of Neurology. PMID 37161609 DOI: 10.1093/brain/awad155 |
0.324 |
|
| 2023 |
Bukreyev A, Ilinykh P, Huang K, Gunn B, Kuzmina N, Gilchuk P, Alter G, Crowe J. Antiviral protection by antibodies targeting the glycan cap of Ebola virus glycoprotein requires activation of the complement system. Research Square. PMID 37131834 DOI: 10.21203/rs.3.rs-2765936/v1 |
0.347 |
|
| 2023 |
Bartsch YC, Cizmeci D, Kang J, Gao H, Shi W, Chandrashekar A, Collier AY, Chen B, Barouch DH, Alter G. Selective SARS-CoV2 BA.2 escape of antibody Fc/Fc-receptor interactions. Iscience. 26: 106582. PMID 37082529 DOI: 10.1016/j.isci.2023.106582 |
0.362 |
|
| 2023 |
Gunn BM, McNamara RP, Wood L, Taylor S, Devadhasan A, Guo W, Das J, Nilsson A, Shurtleff A, Dubey S, Eichberg M, Suscovich TJ, Saphire EO, Lauffenburger D, Coller BA, ... ... Alter G, et al. Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates. Cell Reports. 42: 112402. PMID 37061918 DOI: 10.1016/j.celrep.2023.112402 |
0.34 |
|
| 2023 |
Mackin SR, Desai P, Whitener BM, Karl CE, Liu M, Baric RS, Edwards DK, Chicz TM, McNamara RP, Alter G, Diamond MS. Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2. Nature Microbiology. 8: 569-580. PMID 37012355 DOI: 10.1038/s41564-023-01359-1 |
0.382 |
|
| 2023 |
Adams LE, Leist SR, Dinnon KH, West A, Gully KL, Anderson EJ, Loome JF, Madden EA, Powers JM, Schäfer A, Sarkar S, Castillo IN, Maron JS, McNamara RP, Bertera HL, ... ... Alter G, et al. Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination. Cell Reports. 42: 112326. PMID 37000623 DOI: 10.1016/j.celrep.2023.112326 |
0.316 |
|
| 2023 |
Boudreau CM, Burke JS, Roederer AL, Gorman MJ, Mundle S, Lingwood D, Delagrave S, Sridhar S, Ross TM, Kleanthous H, Alter G. Pre-existing Fc profiles shape the evolution of neutralizing antibody breadth following influenza vaccination. Cell Reports. Medicine. 100975. PMID 36921600 DOI: 10.1016/j.xcrm.2023.100975 |
0.316 |
|
| 2023 |
Wiens KE, Iyer AS, Bhuiyan TR, Lu LL, Cizmeci D, Gorman MJ, Yuan D, Becker RL, Ryan ET, Calderwood SB, LaRocque RC, Chowdhury F, Khan AI, Levine MM, Chen WH, ... ... Alter G, et al. Predicting Vibrio cholerae infection and symptomatic disease: a systems serology study. The Lancet. Microbe. PMID 36907197 DOI: 10.1016/S2666-5247(22)00391-3 |
0.346 |
|
| 2023 |
Loos C, Coccia M, Didierlaurent AM, Essaghir A, Fallon JK, Lauffenburger D, Luedemann C, Michell A, van der Most R, Zhu AL, Alter G, Burny W. Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design. Npj Vaccines. 8: 34. PMID 36890168 DOI: 10.1038/s41541-023-00613-1 |
0.345 |
|
| 2023 |
Mthembu M, Bowman KA, Davies LRL, Khuzwayo S, Mazibuko L, Bassett T, Ramjit D, Mhlane Z, Karim F, Alter G, Ndung'u T, Wong EB. Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts. Ebiomedicine. 90: 104504. PMID 36870197 DOI: 10.1016/j.ebiom.2023.104504 |
0.35 |
|
| 2023 |
Muir R, Metcalf T, Fourati S, Bartsch Y, Lugemwa JK, Canderan G, Alter G, Muyanja E, Okech B, Namatovu T, Namara I, Namuniina A, Ssetaala A, Mpendo J, Nanvubya A, et al. infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses. Medrxiv : the Preprint Server For Health Sciences. PMID 36865336 DOI: 10.1101/2023.02.24.23284435 |
0.307 |
|
| 2023 |
Schnittman SR, Jung W, Fitch KV, Zanni MV, McCallum S, Lee JS, Shin S, Davis BJ, Fulda ES, Diggs MR, Giguel F, Chinchay R, Sheth AN, Fichtenbaum CJ, Malvestutto CD, ... ... Alter G, et al. Impact of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV. Jci Insight. PMID 36805331 DOI: 10.1172/jci.insight.166848 |
0.35 |
|
| 2023 |
Pušnik J, Monzon-Posadas WO, Zorn J, Peters K, Baum M, Proksch H, Schlüter CB, Alter G, Menting T, Streeck H. SARS-CoV-2 humoral and cellular immunity following different combinations of vaccination and breakthrough infection. Nature Communications. 14: 572. PMID 36732523 DOI: 10.1038/s41467-023-36250-4 |
0.316 |
|
| 2023 |
Nielsen CM, Barrett JR, Davis C, Fallon JK, Goh C, Michell AR, Griffin C, Kwok A, Loos C, Darko S, Laboune F, Tekman M, Diouf A, Miura K, Francica JR, ... ... Alter G, et al. Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine. Jci Insight. 8. PMID 36692019 DOI: 10.1172/jci.insight.163859 |
0.302 |
|
| 2022 |
Bartsch YC, Cizmeci D, Kang J, Zohar T, Periasamy S, Mehta N, Tolboom J, Van der Fits L, Sadoff J, Comeaux C, Callendret B, Bukreyev A, Lauffenburger DA, Bastian AR, Alter G. Antibody effector functions are associated with protection from respiratory syncytial virus. Cell. 185: 4873-4886.e10. PMID 36513064 DOI: 10.1016/j.cell.2022.11.012 |
0.388 |
|
| 2022 |
Mackin SR, Desai P, Whitener BM, Karl CE, Liu M, Baric RS, Edwards DK, Chicz TM, McNamara RP, Alter G, Diamond MS. Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 36482975 DOI: 10.1101/2022.11.27.518117 |
0.384 |
|
| 2022 |
Adams LE, Leist SR, Dinnon KH, West A, Gully KL, Anderson EJ, Loome JF, Madden EA, Powers JM, Schäfer A, Sarkar S, Castillo IN, Maron JS, McNamara RP, Bertera HL, ... ... Alter G, et al. Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination. Biorxiv : the Preprint Server For Biology. PMID 36482964 DOI: 10.1101/2022.11.28.518175 |
0.324 |
|
| 2022 |
Stieh DJ, Barouch DH, Comeaux C, Sarnecki M, Stephenson KE, Walsh SR, Sawant S, Heptinstall J, Tomaras GD, Kublin JG, McElrath MJ, Cohen KW, De Rosa SC, Alter G, Ferrari G, et al. Safety and Immunogenicity of Ad26-vectored HIV Vaccine with Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-uninfected Adults: A Phase 1/2a Study. The Journal of Infectious Diseases. PMID 36348617 DOI: 10.1093/infdis/jiac445 |
0.371 |
|
| 2022 |
Hadjichrysanthou C, Beukenhorst AL, Koch CM, Alter G, Goudsmit J, Anderson RM, de Wolf F. Exploring the Role of Antiviral Nasal Sprays in the Control of Emerging Respiratory Infections in the Community. Infectious Diseases and Therapy. PMID 36309921 DOI: 10.1007/s40121-022-00710-z |
0.315 |
|
| 2022 |
Herman JD, Atyeo C, Zur Y, Cook CE, Patel NJ, Vanni KM, Kowalski EN, Qian G, Shadick NA, Laffenburger D, Wallace ZS, Sparks JA, Alter G. Impact of cross-coronavirus immunity in post-acute sequelae of COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 36203557 DOI: 10.1101/2022.09.25.22280335 |
0.363 |
|
| 2022 |
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schäfer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, ... ... Alter G, et al. IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern. Nature Communications. 13: 5814. PMID 36192374 DOI: 10.1038/s41467-022-33030-4 |
0.308 |
|
| 2022 |
Karsten CB, Bartsch YC, Shin SA, Slein MD, Heller HM, Kolandaivelu K, Middeldorp JM, Alter G, Julg B. Evolution of functional antibodies following acute Epstein-Barr virus infection. Plos Pathogens. 18: e1010738. PMID 36067220 DOI: 10.1371/journal.ppat.1010738 |
0.358 |
|
| 2022 |
Bowman KA, Stein D, Shin S, Ferbas KG, Tobin NH, Mann C, Fischinger S, Ollmann Saphire E, Lauffenburger D, Rimoin AW, Aldrovandi G, Alter G. Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity. Mbio. e0164722. PMID 36000735 DOI: 10.1128/mbio.01647-22 |
0.37 |
|
| 2022 |
Bernshtein B, Ndungo E, Cizmeci D, Xu P, Kováč P, Kelly M, Islam D, Ryan ET, Kotloff KL, Pasetti MF, Alter G. Systems approach to define humoral correlates of immunity to Shigella. Cell Reports. 40: 111216. PMID 35977496 DOI: 10.1016/j.celrep.2022.111216 |
0.377 |
|
| 2022 |
Zohar T, Atyeo C, Wolf CR, Logue JK, Shuey K, Franko N, Choi RY, Wald A, Koelle DM, Chu HY, Lauffenburger DA, Alter G. A multifaceted high-throughput assay for probing antigen-specific antibody-mediated primary monocyte phagocytosis and downstream functions. Journal of Immunological Methods. 113328. PMID 35934070 DOI: 10.1016/j.jim.2022.113328 |
0.336 |
|
| 2022 |
Davies LRL, Cizmeci D, Guo W, Luedemann C, Alexander-Parrish R, Grant L, Isturiz R, Theilacker C, Jodar L, Gessner BD, Alter G. Polysaccharide and conjugate vaccines to generate distinct humoral responses. Science Translational Medicine. 14: eabm4065. PMID 35921476 DOI: 10.1126/scitranslmed.abm4065 |
0.31 |
|
| 2022 |
Sahoo A, Jones AT, Cheedarla N, Gangadhara S, Roy V, Styles TM, Shiferaw A, Walter KL, Williams LD, Shen X, Ozorowski G, Lee WH, Burton S, Yi L, Song X, ... ... Alter G, et al. A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques. Science Immunology. 7: eabl4102. PMID 35867800 DOI: 10.1126/sciimmunol.abl4102 |
0.408 |
|
| 2022 |
Pušnik J, König J, Mai K, Richter E, Zorn J, Proksch H, Schulte B, Alter G, Streeck H. Persistent Maintenance of Intermediate Memory B Cells Following SARS-CoV-2 Infection and Vaccination Recall Response. Journal of Virology. e0076022. PMID 35862718 DOI: 10.1128/jvi.00760-22 |
0.386 |
|
| 2022 |
Dias AG, Atyeo C, Loos C, Montoya M, Roy V, Bos S, Narvekar P, Singh T, Katzelnick LC, Kuan G, Lauffenburger DA, Balmaseda A, Alter G, Harris E. Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection. Science Translational Medicine. 14: eabm3151. PMID 35767652 DOI: 10.1126/scitranslmed.abm3151 |
0.371 |
|
| 2022 |
Wang C, Li Y, Kaplonek P, Gentili M, Fischinger S, Bowman KA, Sade-Feldman M, Kays KR, Regan J, Flynn JP, Goldberg MB, Hacohen N, Filbin MR, Lauffenburger DA, Alter G, et al. The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia. Mbio. e0157722. PMID 35762593 DOI: 10.1128/mbio.01577-22 |
0.318 |
|
| 2022 |
Zimmerman O, Altman Doss AM, Kaplonek P, Liang CY, VanBlargan LA, Chen RE, Monroy JM, Wedner HJ, Kulczycki A, Mantia TL, O'Shaughnessy CC, Davis-Adams HG, Bertera HL, Adams LJ, Raju S, ... ... Alter G, et al. mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes. Cell Reports. Medicine. 100653. PMID 35688161 DOI: 10.1016/j.xcrm.2022.100653 |
0.356 |
|
| 2022 |
Goldblatt D, Alter G, Crotty S, Plotkin SA. Correlates of protection against SARS-CoV-2 infection and COVID-19 disease. Immunological Reviews. PMID 35661178 DOI: 10.1111/imr.13091 |
0.363 |
|
| 2022 |
Nziza N, Cizmeci D, Davies L, Irvine EB, Jung W, Fenderson BA, de Kock M, Hanekom WA, Franken KLMC, Day CL, Ottenhoff THM, Alter G. Defining Discriminatory Antibody Fingerprints in Active and Latent Tuberculosis. Frontiers in Immunology. 13: 856906. PMID 35514994 DOI: 10.3389/fimmu.2022.856906 |
0.411 |
|
| 2022 |
Zhu DY, Gorman MJ, Yuan D, Yu J, Mercado NB, McMahan K, Borducchi EN, Lifton M, Liu J, Nampanya F, Patel S, Peter L, Tostanoski LH, Pessaint L, Van Ry A, ... ... Alter G, et al. Defining the determinants of protection against SARS-CoV-2 infection and viral control in a dose-down Ad26.CoV2.S vaccine study in nonhuman primates. Plos Biology. 20: e3001609. PMID 35512013 DOI: 10.1371/journal.pbio.3001609 |
0.373 |
|
| 2022 |
Spatola M, Loos C, Cizmeci D, Webb N, Gorman MJ, Rossignol E, Shin S, Yuan D, Fontana L, Mukerji SS, Lauffenburger DA, Gabuzda D, Alter G. Functional compartmentalization of antibodies in the central nervous system during chronic HIV infection. The Journal of Infectious Diseases. PMID 35417540 DOI: 10.1093/infdis/jiac138 |
0.42 |
|
| 2022 |
Overton ET, Weir IR, Zanni MV, Fischinger S, MacArthur RD, Aberg JA, Fitch KV, Frank M, Albrecht H, Goodenough E, Rhame FS, Fichtenbaum CJ, Bloomfield GS, Malvestutto C, Supparatpinyo K, ... ... Alter G, et al. Asymptomatic SARS-CoV-2 Infection is Common among ART-treated People with HIV. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 35413022 DOI: 10.1097/QAI.0000000000003000 |
0.333 |
|
| 2022 |
Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, ... ... Alter G, et al. mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions. Science Translational Medicine. eabm2311. PMID 35348368 DOI: 10.1126/scitranslmed.abm2311 |
0.313 |
|
| 2022 |
Bartsch YC, Tong X, Kang J, Avendaño MJ, Serrano EF, García-Salum T, Pardo-Roa C, Riquelme A, Cai Y, Renzi I, Stewart-Jones G, Chen B, Medina RA, Alter G. Omicron variant Spike-specific antibody binding and Fc activity is preserved in recipients of mRNA or inactivated COVID-19 vaccines. Science Translational Medicine. eabn9243. PMID 35289637 DOI: 10.1126/scitranslmed.abn9243 |
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| 2022 |
Lakhashe SK, Amacker M, Hariraju D, Vyas HK, Morrison KS, Weiner JA, Ackerman ME, Roy V, Alter G, Ferrari G, Montefiori DC, Tomaras GD, Sawant S, Yates NL, Gast C, et al. Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges. Frontiers in Immunology. 13: 788619. PMID 35273592 DOI: 10.3389/fimmu.2022.788619 |
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| 2022 |
Dolatshahi S, Butler AL, Siedner MJ, Ngonzi J, Edlow AG, Adong J, Jennewein MF, Atyeo C, Bassett IV, Roberts DJ, Lauffenburger DA, Alter G, Bebell LM. Altered maternal antibody profiles in women with HIV drive changes in transplacental antibody transfer. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 35245365 DOI: 10.1093/cid/ciac156 |
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| 2022 |
Kaplonek P, Fischinger S, Cizmeci D, Bartsch YC, Kang J, Burke JS, Shin SA, Dayal D, Martin P, Mann C, Amanat F, Julg B, Nilles EJ, Musk ER, Menon AS, ... ... Alter G, et al. mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern. Immunity. PMID 35090580 DOI: 10.1016/j.immuni.2022.01.001 |
0.34 |
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| 2022 |
Siddiqui SM, Bowman KA, Zhu AL, Fischinger S, Beger S, Maron JS, Bartsch YC, Atyeo C, Gorman MJ, Yanis A, Hultquist JF, Lorenzo-Redondo R, Ozer EA, Simons LM, Talj R, ... ... Alter G, et al. Serological Markers of SARS-CoV-2 Reinfection. Mbio. e0214121. PMID 35073738 DOI: 10.1128/mbio.02141-21 |
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| 2022 |
Haydu JE, Maron JS, Redd RA, Gallagher KME, Fischinger S, Barnes JA, Hochberg EP, Johnson PC, Takvorian RW, Katsis K, Portman D, Ruiters J, Sechio S, Devlin MC, Regan C, ... ... Alter G, et al. Humoral and cellular immunogenicity of SARS-CoV-2 vaccines in chronic lymphocytic leukemia: a prospective cohort study. Blood Advances. PMID 35073571 DOI: 10.1182/bloodadvances.2021006627 |
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| 2022 |
Richter E, Bornemann L, Korencak M, Alter G, Schuster M, Esser S, Boesecke C, Rockstroh J, Gunzer M, Streeck H. Reduction of CD8 T Cell Functionality but Not Inhibitory Capacity by Integrase Inhibitors. Journal of Virology. 96: e0173021. PMID 35019724 DOI: 10.1128/JVI.01730-21 |
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| 2022 |
Zohar T, Hsiao JC, Mehta N, Das J, Devadhasan A, Karpinski W, Callahan C, Citron MP, DiStefano DJ, Touch S, Wen Z, Sachs JR, Cejas PJ, Espeseth AS, Lauffenburger DA, ... ... Alter G, et al. Upper and lower respiratory tract correlates of protection against respiratory syncytial virus following vaccination of nonhuman primates. Cell Host & Microbe. 30: 41-52.e5. PMID 34879230 DOI: 10.1016/j.chom.2021.11.006 |
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| 2021 |
Bartsch Y, Tong X, Kang J, Avendaño MJ, Serrano EF, García-Salum T, Pardo-Roa C, Riquelme A, Medina RA, Alter G. Preserved Omicron Spike specific antibody binding and Fc-recognition across COVID-19 vaccine platforms. Medrxiv : the Preprint Server For Health Sciences. PMID 34981072 DOI: 10.1101/2021.12.24.21268378 |
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| 2021 |
Fischinger S, Cizmeci D, Deng D, Grant SP, Frahm N, McElrath J, Fuchs J, Bart PA, Pantaleo G, Keefer M, O Hahn W, Rouphael N, Churchyard G, Moodie Z, Donastorg Y, ... ... Alter G, et al. Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials. Plos Pathogens. 17: e1010016. PMID 34843602 DOI: 10.1371/journal.ppat.1010016 |
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| 2021 |
Herman JD, Wang C, Loos C, Yoon H, Rivera J, Eugenia Dieterle M, Haslwanter D, Jangra RK, Bortz RH, Bar KJ, Julg B, Chandran K, Lauffenburger D, Pirofski LA, Alter G. Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response. Nature Communications. 12: 6853. PMID 34824251 DOI: 10.1038/s41467-021-27201-y |
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| 2021 |
Irvine EB, O'Neil A, Darrah PA, Shin S, Choudhary A, Li W, Honnen W, Mehra S, Kaushal D, Gideon HP, Flynn JL, Roederer M, Seder RA, Pinter A, Fortune S, ... Alter G, et al. Robust IgM responses following intravenous vaccination with Bacille Calmette-Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques. Nature Immunology. 22: 1515-1523. PMID 34811542 DOI: 10.1038/s41590-021-01066-1 |
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| 2021 |
Pullen KM, Atyeo C, Collier AY, Gray KJ, Belfort MB, Lauffenburger DA, Edlow AG, Alter G. Selective functional antibody transfer into the breastmilk after SARS-CoV-2 infection. Cell Reports. 37: 109959. PMID 34739850 DOI: 10.1016/j.celrep.2021.109959 |
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| 2021 |
Cheng HD, Dowell KG, Bailey-Kellogg C, Goods BA, Love JC, Ferrari G, Alter G, Gach J, Forthal DN, Lewis GK, Greene K, Gao H, Montefiori DC, Ackerman ME. Diverse antiviral IgG effector activities are predicted by unique biophysical antibody features. Retrovirology. 18: 35. PMID 34717659 DOI: 10.1186/s12977-021-00579-9 |
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| 2021 |
Fischinger S, Cizmeci D, Shin S, Davies L, Grace PS, Sivro A, Yende-Zuma N, Streeck H, Fortune SM, Lauffenburger DA, Naidoo K, Alter G. A Specific IgG3 Signature of Recurrent Tuberculosis. Frontiers in Immunology. 12: 729186. PMID 34630406 DOI: 10.3389/fimmu.2021.729186 |
0.342 |
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| 2021 |
Kammers K, Chen A, Monaco DR, Hudelson SE, Grant-McAuley W, Moore RD, Alter G, Deeks SG, Morrison CS, Eller LA, Blankson JN, Laeyendecker O, Ruczinski I, Eshleman SH, Larman HB. HIV Antibody Profiles in HIV Controllers and Persons With Treatment-Induced Viral Suppression. Frontiers in Immunology. 12: 740395. PMID 34512672 DOI: 10.3389/fimmu.2021.740395 |
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| 2021 |
Gorman MJ, Patel N, Guebre-Xabier M, Zhu AL, Atyeo C, Pullen KM, Loos C, Goez-Gazi Y, Carrion R, Tian JH, Yuan D, Bowman KA, Zhou B, Maciejewski S, McGrath ME, ... ... Alter G, et al. Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination. Cell Reports. Medicine. 100405. PMID 34485950 DOI: 10.1016/j.xcrm.2021.100405 |
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| 2021 |
Williamson LE, Reeder KM, Bailey K, Tran MH, Roy V, Fouch ME, Kose N, Trivette A, Nargi RS, Winkler ES, Kim AS, Gainza C, Rodriguez J, Armstrong E, Sutton RE, ... ... Alter G, et al. Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress. Cell. 184: 4430-4446.e22. PMID 34416147 DOI: 10.1016/j.cell.2021.07.033 |
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| 2021 |
Kim AS, Kafai NM, Winkler ES, Gilliland TC, Cottle EL, Earnest JT, Jethva PN, Kaplonek P, Shah AP, Fong RH, Davidson E, Malonis RJ, Quiroz JA, Williamson LE, Vang L, ... ... Alter G, et al. Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope. Cell. 184: 4414-4429.e19. PMID 34416146 DOI: 10.1016/j.cell.2021.07.006 |
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| 2021 |
Gilchuk P, Guthals A, Bonissone SR, Shaw JB, Ilinykh PA, Huang K, Bombardi RG, Liang J, Grinyo A, Davidson E, Chen EC, Gunn BM, Alter G, Saphire EO, Doranz BJ, et al. Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma. Frontiers in Immunology. 12: 706757. PMID 34335620 DOI: 10.3389/fimmu.2021.706757 |
0.323 |
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| 2021 |
Francica JR, Flynn BJ, Foulds KE, Noe AT, Werner AP, Moore IN, Gagne M, Johnston TS, Tucker C, Davis RL, Flach B, O'Connell S, Andrew SF, Lamb E, Flebbe DR, ... ... Alter G, et al. Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates. Science Translational Medicine. PMID 34315825 DOI: 10.1126/scitranslmed.abi4547 |
0.337 |
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| 2021 |
Meyer M, Gunn BM, Malherbe DC, Gangavarapu K, Yoshida A, Pietzsch C, Kuzmina NA, Saphire EO, Collins PL, Crowe JE, Zhu JJ, Suchard MA, Brining DL, Mire CE, Cross RW, ... ... Alter G, et al. Ebola vaccine-induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects. Science Translational Medicine. 13. PMID 34261800 DOI: 10.1126/scitranslmed.abg6128 |
0.31 |
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| 2021 |
Young WC, Carpp LN, Chaudhury S, Regules JA, Bergmann-Leitner ES, Ockenhouse C, Wille-Reece U, deCamp AC, Hughes E, Mahoney C, Pallikkuth S, Pahwa S, Dennison SM, Mudrak SV, Alam SM, ... ... Alter G, et al. Comprehensive Data Integration Approach to Assess Immune Responses and Correlates of RTS,S/AS01-Mediated Protection From Malaria Infection in Controlled Human Malaria Infection Trials. Frontiers in Big Data. 4: 672460. PMID 34212134 DOI: 10.3389/fdata.2021.672460 |
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| 2021 |
Routhu NK, Cheedarla N, Bollimpelli VS, Gangadhara S, Edara VV, Lai L, Sahoo A, Shiferaw A, Styles TM, Floyd K, Fischinger S, Atyeo C, Shin SA, Gumber S, Kirejczyk S, ... ... Alter G, et al. SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung. Nature Communications. 12: 3587. PMID 34117252 DOI: 10.1038/s41467-021-23942-y |
0.375 |
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| 2021 |
Nduati EW, Gorman MJ, Sein Y, Hermanus T, Oyaro I, Muema DM, Ndung'u T, Alter G, Moore PL. Coordinated Fc-effector and neutralization functions in HIV-infected children define a window of opportunity for HIV vaccination. Aids (London, England). PMID 34115644 DOI: 10.1097/QAD.0000000000002976 |
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| 2021 |
Alter G, Yu J, Liu J, Chandrashekar A, Borducchi EN, Tostanoski LH, McMahan K, Jacob-Dolan C, Martinez DR, Chang A, Anioke T, Lifton M, Nkolola J, Stephenson KE, Atyeo C, et al. Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans. Nature. PMID 34107529 DOI: 10.1038/s41586-021-03681-2 |
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Paquin-Proulx D, Gunn BM, Alrubayyi A, Clark DV, Creegan M, Kim D, Kibuuka H, Millard M, Wakabi S, Eller LA, Michael NL, Schoepp RJ, Hepburn MJ, Hensley LE, Robb ML, ... Alter G, et al. Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors. Frontiers in Immunology. 12: 682120. PMID 34093585 DOI: 10.3389/fimmu.2021.682120 |
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Rossignol ED, Dugast AS, Compere H, Cottrell CA, Copps J, Lin S, Cizmeci D, Seaman MS, Ackerman ME, Ward AB, Alter G, Julg B. Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells. Cell Reports. 35: 109167. PMID 34038720 DOI: 10.1016/j.celrep.2021.109167 |
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Kaplonek P, Wang C, Bartsch Y, Fischinger S, Gorman MJ, Bowman K, Kang J, Dayal D, Martin P, Nowak R, Hsieh CL, Feldman J, Julg B, Nilles EJ, Musk ER, ... ... Alter G, et al. Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19. Biorxiv : the Preprint Server For Biology. PMID 34013263 DOI: 10.1101/2021.05.11.443609 |
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Gunn BM, Lu R, Slein MD, Ilinykh PA, Huang K, Atyeo C, Schendel SL, Kim J, Cain C, Roy V, Suscovich TJ, Takada A, Halfmann PJ, Kawaoka Y, Pauthner MG, ... ... Alter G, et al. A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus. Immunity. 54: 815-828.e5. PMID 33852832 DOI: 10.1016/j.immuni.2021.03.009 |
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Cizmeci D, Lofano G, Rossignol E, Dugast AS, Kim D, Cavet G, Nguyen N, Tan YC, Seaman MS, Alter G, Julg B. Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth. Elife. 10. PMID 33843586 DOI: 10.7554/eLife.62648 |
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Pedreño-Lopez N, Rosen BC, Flores WJ, Gorman MJ, Voigt TB, Ricciardi MJ, Crosno K, Weisgrau KL, Parks CL, Lifson JD, Alter G, Rakasz EG, Magnani DM, Martins MA, Watkins DI. Non-neutralizing Antibodies May Contribute to Suppression of SIVmac239 Viremia in Indian Rhesus Macaques. Frontiers in Immunology. 12: 657424. PMID 33796119 DOI: 10.3389/fimmu.2021.657424 |
0.45 |
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| 2021 |
Herman JD, Wang C, Loos C, Yoon H, Rivera J, Dieterle ME, Haslwanter D, Jangra RK, Bortz RH, Bar KJ, Julg B, Chandran K, Lauffenburger D, Pirofski LA, Alter G. Functional Antibodies in COVID-19 Convalescent Plasma. Medrxiv : the Preprint Server For Health Sciences. PMID 33758875 DOI: 10.1101/2021.03.08.21253157 |
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| 2021 |
Francica JR, Flynn BJ, Foulds KE, Noe AT, Werner AP, Moore IN, Gagne M, Johnston TS, Tucker C, Davis RL, Flach B, O'Connell S, Andrew SF, Lamb E, Flebbe DR, ... ... Alter G, et al. Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates. Biorxiv : the Preprint Server For Biology. PMID 33688652 DOI: 10.1101/2021.03.02.433390 |
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Bartsch YC, Loos C, Rossignol E, Fajnzylber JM, Yuan D, Avihingsanon A, Ubolyam S, Jupimai T, Hirschel B, Ananworanich J, Lauffenburger DA, Li JZ, Alter G, Julg B. Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features. Mbio. 12. PMID 33688003 DOI: 10.1128/mBio.00170-21 |
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| 2021 |
Mdluli T, Jian N, Slike B, Paquin-Proulx D, Donofrio G, Alrubayyi A, Gift S, Grande R, Bryson M, Lee A, Dussupt V, Mendez-Rivera L, Sanders-Buell E, Chenine AL, Tran U, ... ... Alter G, et al. Correction: RV144 HIV-1 vaccination impacts post-infection antibody responses. Plos Pathogens. 17: e1009386. PMID 33651828 DOI: 10.1371/journal.ppat.1009386 |
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Routhu NK, Cheedarla N, Gangadhara S, Bollimpelli VS, Boddapati AK, Shiferaw A, Rahman SA, Sahoo A, Edara VV, Lai L, Floyd K, Wang S, Fischinger S, Atyeo C, Shin SA, ... ... Alter G, et al. A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs. Immunity. PMID 33631118 DOI: 10.1016/j.immuni.2021.02.001 |
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Alter G, Gorman M, Patel N, Guebre-Xabier M, Zhu A, Atyeo C, Pullen K, Loos C, Goez-Gazi Y, Carrion R, Tian JH, Yuan D, Bowman K, Zhou B, Maciejewski S, et al. Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination. Research Square. PMID 33619473 DOI: 10.21203/rs.3.rs-200342/v1 |
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Bartsch YC, Fischinger S, Siddiqui SM, Chen Z, Yu J, Gebre M, Atyeo C, Gorman MJ, Zhu AL, Kang J, Burke JS, Slein M, Gluck MJ, Beger S, Hu Y, ... ... Alter G, et al. Discrete SARS-CoV-2 antibody titers track with functional humoral stability. Nature Communications. 12: 1018. PMID 33589636 DOI: 10.1038/s41467-021-21336-8 |
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Rossignol E, Alter G, Julg B. Antibodies for Human Immunodeficiency Virus-1 Cure Strategies. The Journal of Infectious Diseases. 223: 22-31. PMID 33586772 DOI: 10.1093/infdis/jiaa165 |
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Webb NE, Bernshtein B, Alter G. Tissues: the unexplored frontier of antibody mediated immunity. Current Opinion in Virology. 47: 52-67. PMID 33581646 DOI: 10.1016/j.coviro.2021.01.001 |
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Gorman MJ, Patel N, Guebre-Xabier M, Zhu A, Atyeo C, Pullen KM, Loos C, Goez-Gazi Y, Carrion R, Tian JH, Yaun D, Bowman K, Zhou B, Maciejewski S, McGrath ME, ... ... Alter G, et al. Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination. Biorxiv : the Preprint Server For Biology. PMID 33564763 DOI: 10.1101/2021.02.05.429759 |
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Pušnik J, Fischinger S, Dittmer U, Esser S, van Gils MJ, Sanders RW, Alter G, Streeck H. Production of HIV-1 Env-specific antibodies mediating innate immune functions depends on cognate IL-21- secreting CD4+ T cells. Journal of Virology. PMID 33504598 DOI: 10.1128/JVI.02097-20 |
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Pušnik J, Fischinger S, Dittmer U, Esser S, van Gils MJ, Sanders RW, Alter G, Streeck H. Production of HIV-1 Env-specific antibodies mediating innate immune functions depends on cognate IL-21- secreting CD4+ T cells. Journal of Virology. PMID 33504598 DOI: 10.1128/JVI.02097-20 |
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Atyeo C, Slein MD, Fischinger S, Burke J, Schäfer A, Leist SR, Kuzmina NA, Mire C, Honko A, Johnson R, Storm N, Bernett M, Tong P, Zuo T, Lin J, ... ... Alter G, et al. Dissecting strategies to tune the therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022. Jci Insight. 6. PMID 33427208 DOI: 10.1172/jci.insight.143129 |
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Malherbe DC, Domi A, Hauser MJ, Meyer M, Gunn BM, Alter G, Bukreyev A, Guirakhoo F. Modified vaccinia Ankara vaccine expressing Marburg virus-like particles protects guinea pigs from lethal Marburg virus infection. Npj Vaccines. 5: 78. PMID 34471139 DOI: 10.1038/s41541-020-00226-y |
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| 2020 |
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, ... ... Alter G, et al. Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. Npj Vaccines. 5: 72. PMID 33574310 DOI: 10.1038/s41541-020-00223-1 |
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| 2020 |
Atyeo C, Pullen KM, Bordt EA, Fischinger S, Burke J, Michell A, Slein MD, Loos C, Shook LL, Boatin AA, Yockey LJ, Pepin D, Meinsohn MC, Nguyen NMP, Chauvin M, ... ... Alter G, et al. Compromised SARS-CoV-2-specific placental antibody transfer. Cell. PMID 33476549 DOI: 10.1016/j.cell.2020.12.027 |
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| 2020 |
Muenchhoff M, Chung AW, Roider J, Dugast AS, Richardson S, Kløverpris H, Leslie A, Ndung'u T, Moore P, Alter G, Goulder PJR. Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection. Msphere. 5. PMID 33361123 DOI: 10.1128/mSphere.00880-20 |
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| 2020 |
Offersen R, Yu WH, Scully EP, Julg B, Euler Z, Sadanand S, Garcia-Dominguez D, Zheng L, Rasmussen TA, Jennewein MF, Linde C, Sassic J, Lofano G, Vigano S, Stephenson KE, ... ... Alter G, et al. HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound. Cell Reports. 33: 108502. PMID 33326789 DOI: 10.1016/j.celrep.2020.108502 |
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| 2020 |
Mdluli T, Jian N, Slike B, Paquin-Proulx D, Donofrio G, Alrubayyi A, Gift S, Grande R, Bryson M, Lee A, Dussupt V, Mendez-Riveria L, Sanders-Buell E, Chenine AL, Tran U, ... ... Alter G, et al. RV144 HIV-1 vaccination impacts post-infection antibody responses. Plos Pathogens. 16: e1009101. PMID 33290394 DOI: 10.1371/journal.ppat.1009101 |
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| 2020 |
McMahan K, Yu J, Mercado NB, Loos C, Tostanoski LH, Chandrashekar A, Liu J, Peter L, Atyeo C, Zhu A, Bondzie EA, Dagotto G, Gebre MS, Jacob-Dolan C, Li Z, ... ... Alter G, et al. Correlates of protection against SARS-CoV-2 in rhesus macaques. Nature. PMID 33276369 DOI: 10.1038/s41586-020-03041-6 |
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| 2020 |
Zohar T, Loos C, Fischinger S, Atyeo C, Wang C, Slein MD, Burke J, Yu J, Feldman J, Hauser BM, Caradonna T, Schmidt AG, Cai Y, Streeck H, Ryan ET, ... ... Alter G, et al. Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality. Cell. PMID 33207184 DOI: 10.1016/j.cell.2020.10.052 |
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| 2020 |
Tran AC, Diogo GR, Paul MJ, Copland A, Hart P, Mehta N, Irvine EB, Mussá T, Drake PMW, Ivanyi J, Alter G, Reljic R. Mucosal Therapy of Multi-Drug Resistant Tuberculosis With IgA and Interferon-γ. Frontiers in Immunology. 11: 582833. PMID 33193394 DOI: 10.3389/fimmu.2020.582833 |
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| 2020 |
Chen Y, Zuiani A, Fischinger S, Mullur J, Atyeo C, Travers M, Lelis FJN, Pullen KM, Martin H, Tong P, Gautam A, Habibi S, Bensko J, Gakpo D, Feldman J, ... ... Alter G, et al. Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production. Cell. PMID 33171099 DOI: 10.1016/j.cell.2020.10.051 |
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| 2020 |
Wessel AW, Kose N, Bombardi RG, Roy V, Chantima W, Mongkolsapaya J, Edeling MA, Nelson CA, Bosch I, Alter G, Screaton GR, Fremont DH, Crowe JE, Diamond MS. Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy. Nature Communications. 11: 5278. PMID 33077712 DOI: 10.1038/s41467-020-19096-y |
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Das J, Devadhasan A, Linde C, Broge T, Sassic J, Mangano M, O'Keefe S, Suscovich T, Streeck H, Irrinki A, Pohlmeyer C, Min-Oo G, Lin S, Weiner JA, Cihlar T, ... ... Alter G, et al. Mining for humoral correlates of HIV control and latent reservoir size. Plos Pathogens. 16: e1008868. PMID 33048992 DOI: 10.1371/journal.ppat.1008868 |
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| 2020 |
Kroon EE, Kinnear CJ, Orlova M, Fischinger S, Shin S, Boolay S, Walzl G, Jacobs A, Wilkinson RJ, Alter G, Schurr E, Hoal EG, Möller M. An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa. Ebiomedicine. 61: 103053. PMID 33038764 DOI: 10.1016/j.ebiom.2020.103053 |
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| 2020 |
Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, ... ... Alter G, et al. Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients. Science Immunology. 5. PMID 33033172 DOI: 10.1126/sciimmunol.abe0367 |
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Fischinger S, Dolatshahi S, Jennewein MF, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Michael NL, Vasan S, Ackerman ME, Streeck H, Alter G. IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees. Jci Insight. PMID 33031099 DOI: 10.1172/jci.insight.140925 |
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| 2020 |
Baden LR, Stieh DJ, Sarnecki M, Walsh SR, Tomaras GD, Kublin JG, McElrath MJ, Alter G, Ferrari G, Montefiori D, Mann P, Nijs S, Callewaert K, Goepfert P, Edupuganti S, et al. Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study. The Lancet. Hiv. 7: e688-e698. PMID 33010242 DOI: 10.1016/S2352-3018(20)30229-0 |
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| 2020 |
Alter G, Yu WH, Chandrashekar A, Borducchi EN, Ghneim K, Sharma A, Nedellec R, McKenney KR, Linde C, Broge T, Suscovich TJ, Linnekin T, Abbink P, Mercado NB, Nkolola JP, et al. Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques. Cell. 183: 185-196.e14. PMID 33007262 DOI: 10.1016/j.cell.2020.08.033 |
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| 2020 |
Luetscher RND, McKitrick TR, Gao C, Mehta AY, McQuillan AM, Kardish R, Boligan KF, Song X, Lu L, Heimburg-Molinaro J, von Gunten S, Alter G, Cummings RD. Unique repertoire of anti-carbohydrate antibodies in individual human serum. Scientific Reports. 10: 15436. PMID 32963315 DOI: 10.1038/s41598-020-71967-y |
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| 2020 |
Norman M, Gilboa T, Ogata AF, Maley AM, Cohen L, Busch EL, Lazarovits R, Mao CP, Cai Y, Zhang J, Feldman JE, Hauser BM, Caradonna TM, Chen B, Schmidt AG, ... Alter G, et al. Ultrasensitive high-resolution profiling of early seroconversion in patients with COVID-19. Nature Biomedical Engineering. PMID 32948854 DOI: 10.1038/S41551-020-00611-X |
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| 2020 |
Malherbe DC, Domi A, Hauser MJ, Meyer M, Gunn BM, Alter G, Bukreyev A, Guirakhoo F. Modified vaccinia Ankara vaccine expressing Marburg virus-like particles protects guinea pigs from lethal Marburg virus infection. Npj Vaccines. 5: 78. PMID 32922962 DOI: 10.1038/s41541-020-00226-y |
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| 2020 |
Naranbhai V, Chang CC, Beltran WFG, Miller TE, Astudillo MG, Villalba JA, Yang D, Gelfand J, Bernstein BE, Feldman J, Hauser BM, Caradonna TM, Alter G, Murali MR, Jasrasaria R, et al. High seroprevalence of anti-SARS-CoV-2 antibodies in Chelsea, Massachusetts. The Journal of Infectious Diseases. PMID 32906151 DOI: 10.1093/Infdis/Jiaa579 |
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Tostanoski LH, Wegmann F, Martinot AJ, Loos C, McMahan K, Mercado NB, Yu J, Chan CN, Bondoc S, Starke CE, Nekorchuk M, Busman-Sahay K, Piedra-Mora C, Wrijil LM, Ducat S, ... ... Alter G, et al. Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters. Nature Medicine. PMID 32884153 DOI: 10.1038/S41591-020-1070-6 |
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| 2020 |
Loos C, Atyeo C, Fischinger S, Burke J, Slein MD, Streeck H, Lauffenburger D, Ryan ET, Charles RC, Alter G. Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity. Msphere. 5. PMID 32878931 DOI: 10.1128/mSphere.00622-20 |
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| 2020 |
Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, ... ... Alter G, et al. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. PMID 32877699 DOI: 10.1016/J.Cell.2020.08.025 |
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| 2020 |
Alter G, Seder R. The Power of Antibody-Based Surveillance. The New England Journal of Medicine. PMID 32871061 DOI: 10.1056/Nejme2028079 |
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| 2020 |
Jennewein MF, Mabuka J, Papia CL, Boudreau CM, Dong KL, Ackerman ME, Ndung'u T, Alter G. Tracking the Trajectory of Functional Humoral Immune Responses Following Acute HIV Infection. Frontiers in Immunology. 11: 1744. PMID 32849622 DOI: 10.3389/Fimmu.2020.01744 |
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Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, ... ... Alter G, et al. Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses. The Journal of Pediatrics. PMID 32827525 DOI: 10.1016/J.Jpeds.2020.08.037 |
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Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, ... ... Alter G, et al. Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. Npj Vaccines. 5: 72. PMID 32802411 DOI: 10.1038/s41541-020-00223-1 |
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Atyeo C, Fischinger S, Zohar T, Slein MD, Burke J, Loos C, McCulloch DJ, Newman KL, Wolf C, Yu J, Shuey K, Feldman J, Hauser BM, Caradonna T, Schmidt AG, ... ... Alter G, et al. Distinct Early Serological Signatures Track with SARS-CoV-2 Survival. Immunity. PMID 32783920 DOI: 10.1016/J.Immuni.2020.07.020 |
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| 2020 |
Roy V, Fischinger S, Atyeo C, Slein M, Loos C, Balazs A, Luedemann C, Astudillo MG, Yang D, Wesemann D, Charles R, Lafrate AJ, Feldman J, Hauser B, Caradonna T, ... ... Alter G, ... ... Alter G, et al. SARS-CoV-2-specific ELISA development. Journal of Immunological Methods. 112832. PMID 32780998 DOI: 10.1016/J.Jim.2020.112832 |
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| 2020 |
Loos C, Lauffenburger DA, Alter G. Dissecting the antibody-OME: past, present, and future. Current Opinion in Immunology. 65: 89-96. PMID 32755751 DOI: 10.1016/J.Coi.2020.06.003 |
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| 2020 |
Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, ... ... Alter G, et al. Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics. Nature Biomedical Engineering. PMID 32747832 DOI: 10.1038/S41551-020-0594-X |
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| 2020 |
Mercado NB, Zahn R, Wegmann F, Loos C, Chandrashekar A, Yu J, Liu J, Peter L, McMahan K, Tostanoski LH, He X, Martinez DR, Rutten L, Bos R, van Manen D, ... ... Alter G, et al. Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques. Nature. PMID 32731257 DOI: 10.1038/S41586-020-2607-Z |
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| 2020 |
Suscovich TJ, Fallon JK, Das J, Demas AR, Crain J, Linde CH, Michell A, Natarajan H, Arevalo C, Broge T, Linnekin T, Kulkarni V, Lu R, Slein MD, Luedemann C, ... ... Alter G, et al. Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination. Science Translational Medicine. 12. PMID 32718991 DOI: 10.1126/Scitranslmed.Abb4757 |
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| 2020 |
Fischinger S, Shin S, Boudreau CM, Ackerman M, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kim JH, Robb ML, Michael NL, O'Connell RJ, Vasan S, Streeck H, Alter G. Protein-based, but not viral vector alone, HIV vaccine boosting drives an IgG1-biased polyfunctional humoral immune response. Jci Insight. 5. PMID 32554928 DOI: 10.1172/Jci.Insight.135057 |
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| 2020 |
Maciejewski S, Ruckwardt TJ, Morabito KM, Foreman BM, Burgomaster KE, Gordon DN, Pelc RS, DeMaso CR, Ko SY, Fisher BE, Yang ES, Nair D, Foulds KE, Todd JP, Kong WP, ... ... Alter G, et al. Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality. Science Translational Medicine. 12. PMID 32522807 DOI: 10.1126/Scitranslmed.Aaw9066 |
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| 2020 |
Zohar T, Alter G. Dissecting antibody-mediated protection against SARS-CoV-2. Nature Reviews. Immunology. PMID 32514035 DOI: 10.1038/S41577-020-0359-5 |
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| 2020 |
Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado NB, Peter L, Tostanoski LH, Yu J, Maliga Z, Nekorchuk M, Busman-Sahay K, Terry M, Wrijil LM, Ducat S, Martinez DR, ... ... Alter G, et al. SARS-CoV-2 infection protects against rechallenge in rhesus macaques. Science (New York, N.Y.). PMID 32434946 DOI: 10.1126/Science.Abc4776 |
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| 2020 |
Yu J, Tostanoski LH, Peter L, Mercado NB, McMahan K, Mahrokhian SH, Nkolola JP, Liu J, Li Z, Chandrashekar A, Martinez DR, Loos C, Atyeo C, Fischinger S, Burke JS, ... ... Alter G, et al. DNA vaccine protection against SARS-CoV-2 in rhesus macaques. Science (New York, N.Y.). PMID 32434945 DOI: 10.1126/Science.Abc6284 |
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| 2020 |
van Woudenbergh E, Irvine EB, Davies L, de Kock M, Hanekom WA, Day CL, Fortune S, Alter G. HIV Is Associated with Modified Humoral Immune Responses in the Setting of HIV/TB Coinfection. Msphere. 5. PMID 32434838 DOI: 10.1128/mSphere.00104-20 |
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| 2020 |
Felber BK, Lu Z, Hu X, Valentin A, Rosati M, Remmel CAL, Weiner JA, Carpenter MC, Faircloth K, Stanfield-Oakley S, Williams WB, Shen X, Tomaras GD, LaBranche CC, Montefiori D, ... ... Alter G, et al. Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge. Cell Reports. 31: 107624. PMID 32402293 DOI: 10.1016/J.Celrep.2020.107624 |
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| 2020 |
Schifanella L, Barnett SW, Bissa M, Galli V, Doster MN, Vaccari M, Tomaras GD, Shen X, Phogat S, Pal R, Montefiori DC, LaBranche CC, Rao M, Trinh HV, Washington-Parks R, ... ... Alter G, et al. Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type. Plos Pathogens. 16: e1008531. PMID 32343743 DOI: 10.1371/Journal.Ppat.1008531 |
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| 2020 |
Ilinykh PA, Huang K, Santos RI, Gilchuk P, Gunn BM, Karim MM, Liang J, Fouch ME, Davidson E, Parekh DV, Kimble JB, Pietzsch CA, Meyer M, Kuzmina NA, Zeitlin L, ... ... Alter G, et al. Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies. Cell Host & Microbe. PMID 32320678 DOI: 10.1016/J.Chom.2020.03.025 |
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| 2020 |
Harris LD, Khayumbi J, Ongalo J, Sasser LE, Tonui J, Campbell A, Odhiambo FH, Ouma SG, Alter G, Gandhi NR, Day CL. Distinct Human NK Cell Phenotypes and Functional Responses to in Adults From TB Endemic and Non-endemic Regions. Frontiers in Cellular and Infection Microbiology. 10: 120. PMID 32266170 DOI: 10.3389/Fcimb.2020.00120 |
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| 2020 |
Irvine EB, Alter G. Understanding the role of antibody glycosylation through the lens of severe viral and bacterial diseases. Glycobiology. PMID 32103252 DOI: 10.1093/Glycob/Cwaa018 |
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| 2020 |
Chu TH, Crowley AR, Backes I, Chang C, Tay M, Broge T, Tuyishime M, Ferrari G, Seaman MS, Richardson SI, Tomaras GD, Alter G, Leib D, Ackerman ME. Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies. Plos Pathogens. 16: e1008083. PMID 32092122 DOI: 10.1371/Journal.Ppat.1008083 |
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| 2020 |
Stephenson KE, Wegmann F, Tomaka F, Walsh SR, Tan CS, Lavreys L, Ansel JL, Kanjilal DG, Jaegle K, Nkolola JP, Peter L, Fogel R, Bradshaw C, Tyler A, Makoni T, ... ... Alter G, et al. Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17-22). The Lancet. Hiv. PMID 32078815 DOI: 10.1016/S2352-3018(20)30001-1 |
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| 2020 |
Lu LL, Das J, Grace PS, Fortune SM, Restrepo BI, Alter G. Antibody Fc Glycosylation Discriminates Between Latent and Active Tuberculosis. The Journal of Infectious Diseases. PMID 32060529 DOI: 10.1093/Infdis/Jiz643 |
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| 2020 |
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, ... ... Alter G, et al. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity. PMID 32023489 DOI: 10.1016/J.Immuni.2020.01.001 |
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| 2019 |
Boudreau CM, Yu WH, Suscovich TJ, Talbot HK, Edwards KM, Alter G. Selective induction of antibody effector functional responses using MF59-adjuvanted vaccination. The Journal of Clinical Investigation. PMID 31845904 DOI: 10.1172/Jci129520 |
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| 2019 |
Schifanella L, Barnett SW, Bissa M, Galli V, Doster MN, Vaccari M, Tomaras GD, Shen X, Phogat S, Pal R, Montefiori DC, LaBranche CC, Rao M, Trinh HV, Washington-Parks R, ... ... Alter G, et al. ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type. Plos Pathogens. 15: e1008121. PMID 31794588 DOI: 10.1371/journal.ppat.1008121 |
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Tran TM, Guha R, Portugal S, Skinner J, Ongoiba A, Bhardwaj J, Jones M, Moebius J, Venepally P, Doumbo S, DeRiso EA, Li S, Vijayan K, Anzick SL, Hart GT, ... ... Alter G, et al. A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation. Immunity. PMID 31492649 DOI: 10.1016/J.Immuni.2019.08.009 |
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| 2019 |
Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur MS, Das J, Wang H, Guthmiller J, Zheng NY, Huang M, Uphadhyay AA, Gardinassi L, Petitdemange C, McCullough MP, ... ... Alter G, et al. Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell. 178: 1313-1328.e13. PMID 31491384 DOI: 10.1016/J.Cell.2019.08.010 |
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Yu WH, Su D, Torabi J, Fennessey CM, Shiakolas A, Lynch R, Chun TW, Doria-Rose N, Alter G, Seaman MS, Keele BF, Lauffenburger DA, Julg B. Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir. Jci Insight. 4. PMID 31484826 DOI: 10.1172/Jci.Insight.130153 |
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| 2019 |
Ehrenberg PK, Shangguan S, Issac B, Alter G, Geretz A, Izumi T, Bryant C, Eller MA, Wegmann F, Apps R, Creegan M, Bolton DL, Sekaly RP, Robb ML, Gramzinski RA, et al. A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials. Science Translational Medicine. 11. PMID 31462510 DOI: 10.1126/Scitranslmed.Aaw4236 |
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| 2019 |
Butler AL, Fallon JK, Alter G. A Sample-Sparing Multiplexed ADCP Assay. Frontiers in Immunology. 10: 1851. PMID 31456799 DOI: 10.3389/Fimmu.2019.01851 |
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| 2019 |
Earnest JT, Basore K, Roy V, Bailey AL, Wang D, Alter G, Fremont DH, Diamond MS. Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity. The Journal of Experimental Medicine. PMID 31337735 DOI: 10.1084/Jem.20190736 |
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| 2019 |
Fischinger S, Fallon JK, Michell AR, Broge T, Suscovich TJ, Streeck H, Alter G. A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation. Journal of Immunological Methods. PMID 31301278 DOI: 10.1016/J.Jim.2019.07.002 |
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Gunn BM, Roy V, Karim MM, Hartnett JN, Suscovich TJ, Goba A, Momoh M, Sandi JD, Kanneh L, Andersen KG, Shaffer JG, Schieffelin JS, Garry RF, Grant DS, Alter G. Survivors of Ebola virus disease develop polyfunctional antibody responses. The Journal of Infectious Diseases. PMID 31301137 DOI: 10.1093/Infdis/Jiz364 |
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| 2019 |
Angeletti D, Kosik I, Santos JJS, Yewdell WT, Boudreau CM, Mallajosyula VVA, Mankowski MC, Chambers M, Prabhakaran M, Hickman HD, McDermott AB, Alter G, Chaudhuri J, Yewdell JW. Outflanking immunodominance to target subdominant broadly neutralizing epitopes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31213541 DOI: 10.1073/Pnas.1816300116 |
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Jennewein MF, Goldfarb I, Dolatshahi S, Cosgrove C, Noelette FJ, Krykbaeva M, Das J, Sarkar A, Gorman MJ, Fischinger S, Boudreau CM, Brown J, Cooperrider JH, Aneja J, Suscovich TJ, ... ... Alter G, et al. Fc Glycan-Mediated Regulation of Placental Antibody Transfer. Cell. PMID 31204102 DOI: 10.1016/J.Cell.2019.05.044 |
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| 2019 |
Martinez DR, Fong Y, Li SH, Yang F, Jennewein MF, Weiner JA, Harrell EA, Mangold JF, Goswami R, Seage GR, Alter G, Ackerman ME, Peng X, Fouda GG, Permar SR. Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women. Cell. PMID 31204101 DOI: 10.1016/J.Cell.2019.05.046 |
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| 2019 |
Kawahara JY, Irvine EB, Alter G. A Case for Antibodies as Mechanistic Correlates of Immunity in Tuberculosis. Frontiers in Immunology. 10: 996. PMID 31143177 DOI: 10.3389/Fimmu.2019.00996 |
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| 2019 |
Karsten CB, Mehta N, Shin SA, Diefenbach TJ, Slein MD, Karpinski W, Irvine EB, Broge T, Suscovich TJ, Alter G. A versatile high throughput assay to characterize antibody-mediated neutrophil phagocytosis. Journal of Immunological Methods. PMID 31132351 DOI: 10.1016/J.Jim.2019.05.006 |
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| 2019 |
Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, ... ... Alter G, et al. IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure. Nature Medicine. PMID 31110348 DOI: 10.1038/S41591-019-0441-3 |
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| 2019 |
Pittala S, Bagley K, Schwartz JA, Brown EP, Weiner JA, Prado IJ, Zhang W, Xu R, Ota-Setlik A, Pal R, Shen X, Beck C, Ferrari G, Lewis GK, LaBranche CC, ... ... Alter G, et al. Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection. Molecular Systems Biology. 15: e8747. PMID 31048360 DOI: 10.15252/Msb.20188747 |
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| 2019 |
Pušnik J, Eller MA, Tassaneetrithep B, Schultz BT, Eller LA, Nitayaphan S, Kosgei J, Maganga L, Kibuuka H, Alter G, Michael NL, Robb ML, Streeck H. Expansion of stem-cell-like CD4 memory T cells during acute HIV-1 infection is linked to rapid disease progression. Journal of Virology. PMID 31043532 DOI: 10.1128/Jvi.00377-19 |
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Boudreau CM, Alter G. Extra-Neutralizing FcR-Mediated Antibody Functions for a Universal Influenza Vaccine. Frontiers in Immunology. 10: 440. PMID 30949165 DOI: 10.3389/Fimmu.2019.00440 |
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| 2019 |
Magaret CA, Benkeser DC, Williamson BD, Borate BR, Carpp LN, Georgiev IS, Setliff I, Dingens AS, Simon N, Carone M, Simpkins C, Montefiori D, Alter G, Yu WH, Juraska M, et al. Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features. Plos Computational Biology. 15: e1006952. PMID 30933973 DOI: 10.1371/Journal.Pcbi.1006952 |
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Butler AL, Fischinger S, Alter G. The Antibodiome-Mapping the Humoral Immune Response to HIV. Current Hiv/Aids Reports. PMID 30903381 DOI: 10.1007/S11904-019-00432-X |
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| 2019 |
Fox JM, Roy V, Gunn BM, Huang L, Edeling MA, Mack M, Fremont DH, Doranz BJ, Johnson S, Alter G, Diamond MS. Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes. Science Immunology. 4. PMID 30796092 DOI: 10.1126/Sciimmunol.Aav5062 |
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| 2019 |
Chandler KB, Mehta N, Leon DR, Suscovich T, Alter G, Costello CE. Multi-Isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific -Glycosylation Profiles. Molecular & Cellular Proteomics : McP. PMID 30659065 DOI: 10.1074/Mcp.Ra118.001185 |
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Bornholdt ZA, Herbert AS, Mire CE, He S, Cross RW, Wec AZ, Abelson DM, Geisbert JB, James RM, Rahim MN, Zhu W, Borisevich V, Banadyga L, Gunn BM, Agans KN, ... ... Alter G, et al. A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates. Cell Host & Microbe. 25: 49-58.e5. PMID 30629918 DOI: 10.1016/J.Chom.2018.12.005 |
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Wec AZ, Bornholdt ZA, He S, Herbert AS, Goodwin E, Wirchnianski AS, Gunn BM, Zhang Z, Zhu W, Liu G, Abelson DM, Moyer CL, Jangra RK, James RM, Bakken RR, ... ... Alter G, et al. Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection. Cell Host & Microbe. 25: 39-48.e5. PMID 30629917 DOI: 10.1016/J.Chom.2018.12.004 |
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Fischinger S, Boudreau CM, Butler AL, Streeck H, Alter G. Sex differences in vaccine-induced humoral immunity. Seminars in Immunopathology. PMID 30547182 DOI: 10.1007/S00281-018-0726-5 |
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| 2018 |
Kimble JB, Malherbe DC, Meyer M, Gunn BM, Karim MM, Ilinykh PA, Iampietro M, Mohamed KS, Negi S, Gilchuk P, Huang K, Wolf YI, Braun W, Crowe JE, Alter G, et al. ANTIBODY-MEDIATED PROTECTIVE MECHANISMS INDUCED BY A TRIVALENT PARAINFLUENZA-VECTORED EBOLAVIRUS VACCINE. Journal of Virology. PMID 30518655 DOI: 10.1128/Jvi.01845-18 |
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| 2018 |
Welles HC, Jennewein MF, Mason RD, Narpala S, Wang L, Cheng C, Zhang Y, Todd JP, Lifson JD, Balazs AB, Alter G, McDermott AB, Mascola JR, Roederer M. Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge. Plos Pathogens. 14: e1007395. PMID 30517201 DOI: 10.1371/Journal.Ppat.1007395 |
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| 2018 |
Borducchi EN, Liu J, Nkolola JP, Cadena AM, Yu WH, Fischinger S, Broge T, Abbink P, Mercado NB, Chandrashekar A, Jetton D, Peter L, McMahan K, Moseley ET, Bekerman E, ... ... Alter G, et al. Publisher Correction: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys. Nature. PMID 30397346 DOI: 10.1038/S41586-018-0721-Y |
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| 2018 |
Scully EP, Gandhi M, Johnston R, Hoh R, Lockhart A, Dobrowolski C, Pagliuzza A, Milush JM, Baker CA, Girling V, Ellefson A, Gorelick R, Lifson J, Altfeld M, Alter G, et al. Sex-Based Differences in HIV-1 Reservoir Activity and Residual Immune Activation. The Journal of Infectious Diseases. PMID 30371873 DOI: 10.1093/Infdis/Jiy617 |
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| 2018 |
Saphire EO, Schendel SL, Gunn BM, Milligan JC, Alter G. Antibody-mediated protection against Ebola virus. Nature Immunology. 19: 1169-1178. PMID 30333617 DOI: 10.1038/S41590-018-0233-9 |
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| 2018 |
Borducchi EN, Liu J, Nkolola JP, Cadena AM, Yu WH, Fischinger S, Broge T, Abbink P, Mercado NB, Chandrashekar A, Jetton D, Peter L, McMahan K, Moseley ET, Bekerman E, ... ... Alter G, et al. Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys. Nature. PMID 30283138 DOI: 10.1038/S41586-018-0600-6 |
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| 2018 |
Goetghebuer T, Smolen KK, Adler C, Das J, McBride T, Smits G, Lecomte S, Haelterman E, Barlow P, Piedra PA, van der Klis F, Kollmann TR, Lauffenburger DA, Alter G, Levy J, et al. Initiation of anti-retroviral therapy before pregnancy reduces the risk of infection-related hospitalization in HIV-exposed uninfected infants born in a high-income country. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30215689 DOI: 10.1093/Cid/Ciy673 |
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| 2018 |
Pissani F, Schulte B, Eller MA, Schultz BT, Ratto-Kim S, Marovich M, Thongcharoen P, Sriplienchan S, Rerks-Ngarm S, Pitisuttithum P, Esser S, Alter G, Robb ML, Kim JH, Michael NL, et al. Modulation of Vaccine-induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in Humans. Journal of Virology. PMID 30209165 DOI: 10.1128/Jvi.01143-18 |
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| 2018 |
Ackerman ME, Das J, Pittala S, Broge T, Linde C, Suscovich TJ, Brown EP, Bradley T, Natarajan H, Lin S, Sassic JK, O'Keefe S, Mehta N, Goodman D, Sips M, ... ... Alter G, et al. Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV. Nature Medicine. PMID 30177821 DOI: 10.1038/S41591-018-0161-0 |
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| 2018 |
Jennewein MF, Butler AL, Alter G. Neonate-omics: Charting the Unknown Immune Response in Early Life. Cell. 174: 1051-1053. PMID 30142343 DOI: 10.1016/J.Cell.2018.08.001 |
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| 2018 |
Ilinykh PA, Santos RI, Gunn BM, Kuzmina NA, Shen X, Huang K, Gilchuk P, Flyak AI, Younan P, Alter G, Crowe JE, Bukreyev A. Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap. Plos Pathogens. 14: e1007204. PMID 30138408 DOI: 10.1371/Journal.Ppat.1007204 |
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| 2018 |
Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, ... ... Alter G, et al. Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement. Science Immunology. 3. PMID 30120121 DOI: 10.1126/Sciimmunol.Aat7796 |
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| 2018 |
Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, ... ... Alter G, et al. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 174: 938-952.e13. PMID 30096313 DOI: 10.1016/J.Cell.2018.07.033 |
0.456 |
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| 2018 |
Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, ... ... Alter G, et al. A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. Cell Host & Microbe. 24: 221-233.e5. PMID 30092199 DOI: 10.1016/J.Chom.2018.07.009 |
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| 2018 |
Barouch DH, Tomaka FL, Wegmann F, Stieh DJ, Alter G, Robb ML, Michael NL, Peter L, Nkolola JP, Borducchi EN, Chandrashekar A, Jetton D, Stephenson KE, Li W, Korber B, et al. Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19). Lancet (London, England). 392: 232-243. PMID 30047376 DOI: 10.1016/S0140-6736(18)31364-3 |
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| 2018 |
Scully EP, Rutishauser RL, Simoneau CR, Delagrèverie H, Euler Z, Thanh C, Li JZ, Hartig H, Bakkour S, Busch M, Alter G, Marty FM, Wang CC, Deeks SG, Lorch J, et al. Inconsistent HIV reservoir dynamics and immune responses following anti-PD-1 therapy in cancer patients with HIV infection. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 30032204 DOI: 10.1093/Annonc/Mdy259 |
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| 2018 |
Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, ... ... Alter G, et al. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. PMID 30029854 DOI: 10.1016/J.Immuni.2018.06.018 |
0.421 |
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| 2018 |
Miller-Novak LK, Das J, Musich TA, Demberg T, Weiner JA, Venzon DJ, Mohanram V, Vargas-Inchaustegui DA, Tuero I, Ackerman ME, Alter G, Robert-Guroff M. Analysis of complement-mediated lysis of SIV and SIV-infected cells reveals sex differences in vaccine-induced immune responses in Rhesus macaques. Journal of Virology. PMID 30021899 DOI: 10.1128/Jvi.00721-18 |
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| 2018 |
Luke T, Bennett RS, Gerhardt DM, Burdette T, Postnikova E, Mazur S, Honko AN, Oberlander N, Byrum R, Ragland D, St Claire M, Janosko KB, Smith G, Glenn G, Hooper J, ... ... Alter G, et al. Fully Human Immunoglobulin G From Transchromosomic Bovines Treats Nonhuman Primates Infected With Ebola Virus Makona Isolate. The Journal of Infectious Diseases. PMID 30010950 DOI: 10.1093/Infdis/Jiy377 |
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| 2018 |
Alter G, Barouch D. Immune Correlate-Guided HIV Vaccine Design. Cell Host & Microbe. 24: 25-33. PMID 30001521 DOI: 10.1016/J.Chom.2018.06.012 |
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| 2018 |
Alter G, Ottenhoff THM, Joosten SA. Antibody glycosylation in inflammation, disease and vaccination. Seminars in Immunology. PMID 29903548 DOI: 10.1016/J.Smim.2018.05.003 |
0.435 |
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| 2018 |
Simmons JD, Stein CM, Seshadri C, Campo M, Alter G, Fortune S, Schurr E, Wallis RS, Churchyard G, Mayanja-Kizza H, Boom WH, Hawn TR. Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection. Nature Reviews. Immunology. PMID 29895826 DOI: 10.1038/S41577-018-0025-3 |
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| 2018 |
Singh S, Ramírez-Salazar EG, Doueiri R, Valentin A, Rosati M, Hu X, Keele BF, Shen X, Tomaras GD, Ferrari G, LaBranche C, Montefiori DC, Das J, Alter G, Trinh HV, et al. Control of Heterologous SIV infection by DNA and Protein Co-immunization Regimens Combined with Different Toll-like Receptor-4 (TLR-4) Based Adjuvants in Macaques. Journal of Virology. PMID 29793957 DOI: 10.1128/Jvi.00281-18 |
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| 2018 |
Julg B, Alter G. Lymph node fibrosis: a structural barrier to unleashing effective vaccine immunity. The Journal of Clinical Investigation. PMID 29781815 DOI: 10.1172/Jci121053 |
0.376 |
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| 2018 |
Forconi CS, Cosgrove CP, Saikumar-Lakshmi P, Nixon CE, Foley J, Ong'echa JM, Otieno JA, Alter G, Münz C, Moormann AM. Poorly cytotoxic terminally differentiated CD56CD16 NK cells accumulate in Kenyan children with Burkitt lymphomas. Blood Advances. 2: 1101-1114. PMID 29764843 DOI: 10.1182/Bloodadvances.2017015404 |
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| 2018 |
Yu WH, Zhao P, Draghi M, Arevalo C, Karsten CB, Suscovich TJ, Gunn B, Streeck H, Brass AL, Tiemeyer M, Seaman M, Mascola JR, Wells L, Lauffenburger DA, Alter G. Exploiting glycan topography for computational design of Env glycoprotein antigenicity. Plos Computational Biology. 14: e1006093. PMID 29677181 DOI: 10.1371/Journal.Pcbi.1006093 |
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| 2018 |
Baden LR, Walsh SR, Seaman MS, Cohen YZ, Johnson JA, Licona JH, Filter RD, Kleinjan JA, Gothing JA, Jennings J, Peter L, Nkolola J, Abbink P, Borducchi EN, Kirilova M, ... ... Alter G, et al. First-in-Human Randomized Controlled Trial of Mosaic HIV-1 Immunogens Delivered via a Modified Vaccinia Ankara Vector. The Journal of Infectious Diseases. PMID 29669026 DOI: 10.1093/Infdis/Jiy212 |
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| 2018 |
Bricault CA, Kovacs JM, Badamchi-Zadeh A, McKee K, Shields JL, Gunn BM, Neubauer GH, Ghantous F, Jennings J, Gillis L, Perry J, Nkolola JP, Alter G, Chen B, Stephenson KE, et al. Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs. Journal of Virology. PMID 29643249 DOI: 10.1128/Jvi.00369-18 |
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| 2018 |
Richardson SI, Chung AW, Natarajan H, Mabvakure B, Mkhize NN, Garrett N, Abdool Karim S, Moore PL, Ackerman ME, Alter G, Morris L. HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies. Plos Pathogens. 14: e1006987. PMID 29630668 DOI: 10.1371/Journal.Ppat.1006987 |
0.574 |
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| 2018 |
Chung A, Makuba JM, Ndlovu B, Licht A, Robinson H, Ramlakhan Y, Ghebremichael M, Reddy T, Goulder P, Walker B, Ndung'u T, Alter G. Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity. Aids (London, England). PMID 29620716 DOI: 10.1097/Qad.0000000000001812 |
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| 2018 |
Alter G, Dowell KG, Brown EP, Suscovich TJ, Mikhailova A, Mahan AE, Walker BD, Nimmerjahn F, Bailey-Kellogg C, Ackerman ME. High-resolution definition of humoral immune response correlates of effective immunity against HIV. Molecular Systems Biology. 14: e7881. PMID 29581149 DOI: 10.15252/Msb.20177881 |
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| 2018 |
Cheng HD, Grimm SK, Gilman MS, Gwom LC, Sok D, Sundling C, Donofrio G, Hedestam GBK, Bonsignori M, Haynes BF, Lahey TP, Maro I, von Reyn CF, Gorny MK, Zolla-Pazner S, ... ... Alter G, et al. Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site. Jci Insight. 3. PMID 29515029 DOI: 10.1172/Jci.Insight.97018 |
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| 2018 |
Brown EP, Weiner JA, Lin S, Natarajan H, Normandin E, Barouch DH, Alter G, Sarzotti-Kelsoe M, Ackerman ME. Optimization and qualification of an Fc Array assay for assessments of antibodies against HIV-1/SIV. Journal of Immunological Methods. PMID 29395167 DOI: 10.1016/J.Jim.2018.01.013 |
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| 2018 |
Hansen SG, Zak DE, Xu G, Ford JC, Marshall EE, Malouli D, Gilbride RM, Hughes CM, Ventura AB, Ainslie E, Randall KT, Selseth AN, Rundstrom P, Herlache L, Lewis MS, ... ... Alter G, et al. Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine. Nature Medicine. PMID 29334373 DOI: 10.1038/Nm.4473 |
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| 2018 |
King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE, Saphire EO. The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding. Cell Host & Microbe. 23: 101-109.e4. PMID 29324225 DOI: 10.1016/J.Chom.2017.12.003 |
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| 2017 |
Francica JR, Zak DE, Linde C, Siena E, Johnson C, Juraska M, Yates NL, Gunn B, De Gregorio E, Flynn BJ, Valiante NM, Malyala P, Barnett SW, Sarkar P, Singh M, ... ... Alter G, et al. Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs. Blood Advances. 1: 2329-2342. PMID 29296883 DOI: 10.1182/Bloodadvances.2017011411 |
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| 2017 |
Chung AW, Alter G. Systems serology: profiling vaccine induced humoral immunity against HIV. Retrovirology. 14: 57. PMID 29268769 DOI: 10.1186/S12977-017-0380-3 |
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| 2017 |
Sadanand S, Das J, Chung AW, Schoen MK, Lane S, Suscovich TJ, Streeck H, Smith D, Little S, Lauffenburger DA, Richman D, Alter G. Temporal variation in HIV-specific IgG subclass Abs during acute infection differentiates spontaneous controllers from chronic progressors. Aids (London, England). PMID 29239894 DOI: 10.1097/Qad.0000000000001716 |
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| 2017 |
Lu LL, Suscovich TJ, Fortune SM, Alter G. Beyond binding: antibody effector functions in infectious diseases. Nature Reviews. Immunology. PMID 29063907 DOI: 10.1038/Nri.2017.106 |
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| 2017 |
Jennewein MF, Abu-Raya B, Jiang Y, Alter G, Marchant A. Transfer of maternal immunity and programming of the newborn immune system. Seminars in Immunopathology. PMID 28971246 DOI: 10.1007/S00281-017-0653-X |
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| 2017 |
Mabuka JM, Dugast AS, Muema DM, Reddy T, Ramlakhan Y, Euler Z, Ismail N, Moodley A, Dong KL, Morris L, Walker BD, Alter G, Ndung'u T. Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies. Frontiers in Immunology. 8: 1104. PMID 28943879 DOI: 10.3389/Fimmu.2017.01104 |
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| 2017 |
Teigler JE, Zelinskyy G, Eller MA, Bolton DL, Marovich M, Gordon AD, Alrubayyi A, Alter G, Robb ML, Martin JN, Deeks SG, Michael NL, Dittmer U, Streeck H. Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection. Journal of Virology. PMID 28904197 DOI: 10.1128/Jvi.01263-17 |
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| 2017 |
Bradley T, Pollara J, Santra S, Vandergrift N, Pittala S, Bailey-Kellogg C, Shen X, Parks R, Goodman D, Eaton A, Balachandran H, Mach LV, Saunders KO, Weiner JA, Scearce R, ... ... Alter G, et al. Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge. Nature Communications. 8: 15711. PMID 28593989 DOI: 10.1038/Ncomms15711 |
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| 2017 |
Buranapraditkun S, Pissani F, Teigler JE, Schultz BT, Alter G, Marovich M, Robb ML, Eller MA, Martin J, Deeks S, Michael NL, Streeck H. Preservation of peripheral T follicular helper cell function in HIV controllers. Journal of Virology. PMID 28468877 DOI: 10.1128/Jvi.00497-17 |
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| 2017 |
Karsten CB, Alter G. The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design. Cell Reports. 19: 669-670. PMID 28445718 DOI: 10.1016/J.Celrep.2017.04.033 |
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| 2017 |
Jennewein MF, Alter G. The Immunoregulatory Roles of Antibody Glycosylation. Trends in Immunology. PMID 28385520 DOI: 10.1016/J.It.2017.02.004 |
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| 2017 |
Brown EP, Dowell KG, Boesch AW, Normandin E, Mahan AE, Chu T, Barouch DH, Bailey-Kellogg C, Alter G, Ackerman ME. Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles. Journal of Immunological Methods. PMID 28163018 DOI: 10.1016/J.Jim.2017.01.010 |
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| 2017 |
Dugast AS, Arnold K, Lofano G, Moore S, Hoffner M, Simek M, Poignard P, Seaman M, Suscovich T, Pereyra F, Walker BD, Lauffenburger D, Kwon D, Keele BF, Alter G. Virus-driven inflammation is associated with the development of bNAbs in spontaneous controllers of HIV. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 28158448 DOI: 10.1093/Cid/Cix057 |
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| 2017 |
Ackerman ME, Barouch DH, Alter G. Systems serology for evaluation of HIV vaccine trials. Immunological Reviews. 275: 262-270. PMID 28133810 DOI: 10.1111/Imr.12503 |
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| 2017 |
Mehta N, Alter G. Opportunities to exploit antibody glycosylation in vaccination Future Virology. 12: 325-328. DOI: 10.2217/Fvl-2017-0050 |
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| 2017 |
Scully E, Simoneau C, Delagrèverie H, Euler Z, Li JZ, Alter G, Marty FM, Deeks SG, Lorch J, Henrich TJ. OA3-1 HIV reservoir dynamics and immune responses after anti-PD-1 therapy Journal of Virus Eradication. 3: 3. DOI: 10.1016/S2055-6640(20)30838-4 |
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| 2017 |
Goldfarb IT, Jennewein M, Cosgrove C, Brown J, Krykbaeva M, Cooperrider JH, Aneja J, Lauer GM, Kim AY, Alter G, Riley LE. 338: Maternal Tdap: how do antibodies protect newborns against pertussis? American Journal of Obstetrics and Gynecology. 216. DOI: 10.1016/J.Ajog.2016.11.596 |
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| 2016 |
Huang Y, Ferrari G, Alter G, Forthal DN, Kappes JC, Lewis GK, Love JC, Borate B, Harris L, Greene K, Gao H, Phan TB, Landucci G, Goods BA, Dowell KG, et al. Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects. Journal of Immunology (Baltimore, Md. : 1950). 197: 4603-4612. PMID 27913647 DOI: 10.4049/Jimmunol.1601197 |
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| 2016 |
Borducchi EN, Cabral C, Stephenson KE, Liu J, Abbink P, Ng'ang'a D, Nkolola JP, Brinkman AL, Peter L, Lee BC, Jimenez J, Jetton D, Mondesir J, Mojta S, Chandrashekar A, ... ... Alter G, et al. Ad26/MVA Therapeutic Vaccination with TLR7 Stimulation in SIV-Infected Rhesus Monkeys. Nature. PMID 27841870 DOI: 10.1038/Nature20583 |
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| 2016 |
Gunn BM, Alter G. Modulating Antibody Functionality in Infectious Disease and Vaccination. Trends in Molecular Medicine. PMID 27756530 DOI: 10.1016/J.Molmed.2016.09.002 |
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| 2016 |
Weiss ER, Alter G, Ogembo JG, Henderson JL, Tabak B, Bakiş Y, Somasundaran M, Garber M, Selin L, Luzuriaga K. High EBV load and genomic diversity are associated with generation of gp350 specific neutralizing antibodies following Acute Infectious Mononucleosis. Journal of Virology. PMID 27733645 DOI: 10.1128/Jvi.01562-16 |
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| 2016 |
Lu LL, Chung AW, Rosebrock TR, Ghebremichael M, Yu WH, Grace PS, Schoen MK, Tafesse F, Martin C, Leung V, Mahan AE, Sips M, Kumar MP, Tedesco J, Robinson H, ... ... Alter G, et al. A Functional Role for Antibodies in Tuberculosis. Cell. PMID 27667685 DOI: 10.1016/J.Cell.2016.08.072 |
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| 2016 |
Chan YN, Boesch AW, Osei-Owusu NY, Emileh A, Crowley AR, Cocklin SL, Finstad SL, Linde CH, Howell RA, Zentner I, Cocklin S, Miles AR, Eckman JW, Alter G, Schmitz JE, et al. IgG Binding Characteristics of Rhesus Macaque FcγR. Journal of Immunology (Baltimore, Md. : 1950). PMID 27559046 DOI: 10.4049/Jimmunol.1502252 |
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| 2016 |
Sips M, Liu Q, Draghi M, Ghebremichael M, Berger CT, Suscovich TJ, Sun Y, Walker BD, Carrington M, Altfeld M, Brouckaert P, De Jager PL, Alter G. HLA-C levels impact natural killer cell subset distribution and function. Human Immunology. PMID 27521484 DOI: 10.1016/J.Humimm.2016.08.004 |
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| 2016 |
Abbink P, Larocca RA, De La Barrera RA, Bricault CA, Moseley ET, Boyd M, Kirilova M, Li Z, Ng'ang'a D, Nanayakkara O, Nityanandam R, Mercado NB, Borducchi EN, Agarwal A, Brinkman AL, ... ... Alter G, et al. Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys. Science (New York, N.Y.). PMID 27492477 DOI: 10.1126/Science.Aah6157 |
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| 2016 |
Garcia-Beltran WF, Hölzemer A, Martrus G, Chung AW, Pacheco Y, Simoneau CR, Rucevic M, Lamothe-Molina PA, Pertel T, Kim TE, Dugan H, Alter G, Dechanet-Merville J, Jost S, Carrington M, et al. Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1. Nature Immunology. PMID 27455421 DOI: 10.1038/Ni.3513 |
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| 2016 |
Barnett BE, Staupe RP, Odorizzi PM, Palko O, Tomov VT, Mahan AE, Gunn B, Chen D, Paley MA, Alter G, Reiner SL, Lauer GM, Teijaro JR, Wherry EJ. Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 27430722 DOI: 10.4049/Jimmunol.1500368 |
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| 2016 |
Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, ... ... Alter G, et al. International AIDS Society global scientific strategy: towards an HIV cure 2016. Nature Medicine. PMID 27400264 DOI: 10.1038/Nm.4108 |
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| 2016 |
Julg B, Alter G. Broadly Neutralizing Antibodies: Magic Bullets against HIV? Immunity. 44: 1253-4. PMID 27332729 DOI: 10.1016/J.Immuni.2016.06.012 |
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| 2016 |
Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, ... Alter G, et al. Correction: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. Plos Pathogens. 12: e1005694. PMID 27253391 DOI: 10.1371/Journal.Ppat.1005694 |
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| 2016 |
Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, ... ... Alter G, et al. Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition. Nature Medicine. 22: 762-70. PMID 27239761 DOI: 10.1038/Nm.4105 |
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| 2016 |
Sarkar A, Hou HW, Mahan AE, Han J, Alter G. Multiplexed Affinity-Based Separation of Proteins and Cells Using Inertial Microfluidics. Scientific Reports. 6: 23589. PMID 27026280 DOI: 10.1038/Srep23589 |
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| 2016 |
Scully E, Alter G. NK Cells in HIV Disease. Current Hiv/Aids Reports. 13: 85-94. PMID 27002078 DOI: 10.1007/S11904-016-0310-3 |
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| 2016 |
Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, ... Alter G, et al. Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. Plos Pathogens. 12: e1005456. PMID 26982805 DOI: 10.1371/Journal.Ppat.1005456 |
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| 2016 |
Licht A, Alter G. A Drug-Free Zone-Lymph Nodes as a Safe Haven for HIV. Cell Host & Microbe. 19: 275-6. PMID 26962938 DOI: 10.1016/J.Chom.2016.02.018 |
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| 2016 |
Gunn BM, Schneider JR, Shansab M, Bastian AR, Fahrbach KM, Smith AD, Mahan AE, Karim MM, Licht AF, Zvonar I, Tedesco J, Anderson MR, Chapel A, Suscovich TJ, Malaspina DC, ... ... Alter G, et al. Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16. Mucosal Immunology. PMID 26960182 DOI: 10.1038/Mi.2016.8 |
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| 2016 |
Sips M, Krykbaeva M, Diefenbach TJ, Ghebremichael M, Bowman BA, Dugast AS, Boesch AW, Streeck H, Kwon DS, Ackerman ME, Suscovich TJ, Brouckaert P, Schacker TW, Alter G. Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies. Mucosal Immunology. PMID 26883728 DOI: 10.1038/Mi.2016.12 |
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| 2016 |
Veazey RS, Pilch-Cooper HA, Hope TJ, Alter G, Carias AM, Sips M, Wang X, Rodriguez B, Sieg SF, Reich A, Wilkinson P, Cameron MJ, Lederman MM. Prevention of SHIV transmission by topical IFN-β treatment. Mucosal Immunology. PMID 26838048 DOI: 10.1038/Mi.2015.146 |
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| 2016 |
Schultz BT, Teigler JE, Pissani F, Oster AF, Kranias G, Alter G, Marovich M, Eller MA, Dittmer U, Robb ML, Kim JH, Michael NL, Bolton D, Streeck H. Circulating HIV-Specific Interleukin-21(+)CD4(+) T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions. Immunity. 44: 167-178. PMID 26795249 DOI: 10.1016/J.Immuni.2015.12.011 |
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| 2016 |
Ackerman ME, Mikhailova A, Brown EP, Dowell KG, Walker BD, Bailey-Kellogg C, Suscovich TJ, Alter G. Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control. Plos Pathogens. 12: e1005315. PMID 26745376 DOI: 10.1371/Journal.Ppat.1005315 |
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| 2016 |
Sadanand S, Suscovich TJ, Alter G. Broadly Neutralizing Antibodies Against HIV: New Insights to Inform Vaccine Design. Annual Review of Medicine. 67: 185-200. PMID 26565674 DOI: 10.1146/Annurev-Med-091014-090749 |
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| 2016 |
Alter G. G-105 Defining protective antibody profiles against HIV utilizing systems serology Journal of Acquired Immune Deficiency Syndromes. 71: 66. DOI: 10.1097/01.Qai.0000479685.23881.B1 |
0.472 |
|
| 2015 |
Hölzemer A, Thobakgale CF, Jimenez Cruz CA, Garcia-Beltran WF, Carlson JM, van Teijlingen NH, Mann JK, Jaggernath M, Kang SG, Körner C, Chung AW, Schafer JL, Evans DT, Alter G, Walker BD, et al. Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa. Plos Medicine. 12: e1001900. PMID 26575988 DOI: 10.1371/Journal.Pmed.1001900 |
0.508 |
|
| 2015 |
Chung AW, Kumar MP, Arnold KB, Yu WH, Schoen MK, Dunphy LJ, Suscovich TJ, Frahm N, Linde C, Mahan AE, Hoffner M, Streeck H, Ackerman ME, McElrath MJ, Schuitemaker H, ... ... Alter G, et al. Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology. Cell. 163: 988-98. PMID 26544943 DOI: 10.1016/J.Cell.2015.10.027 |
0.501 |
|
| 2015 |
Arnold KB, Szeto GL, Alter G, Irvine DJ, Lauffenburger DA. CD4+ T cell-dependent and CD4+ T cell-independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals. Science Signaling. 8: ra104. PMID 26486173 DOI: 10.1126/Scisignal.Aab0808 |
0.483 |
|
| 2015 |
Gupta PK, Godec J, Wolski D, Adland E, Yates K, Pauken KE, Cosgrove C, Ledderose C, Junger WG, Robson SC, Wherry EJ, Alter G, Goulder PJ, Klenerman P, Sharpe AH, et al. CD39 Expression Identifies Terminally Exhausted CD8+ T Cells. Plos Pathogens. 11: e1005177. PMID 26485519 DOI: 10.1371/Journal.Ppat.1005177 |
0.38 |
|
| 2015 |
Holtsberg FW, Shulenin S, Vu H, Howell KA, Patel SJ, Gunn B, Karim M, Lai JR, Frei JC, Nyakatura EK, Zeitlin L, Douglas R, Fusco ML, Froude JW, Saphire EO, ... ... Alter G, et al. Pan-ebolavirus and pan-filovirus mouse monoclonal antibodies: protection against Ebola and Sudan viruses. Journal of Virology. PMID 26468533 DOI: 10.1128/Jvi.02171-15 |
0.447 |
|
| 2015 |
Townsley E, O'Connor G, Cosgrove C, Woda M, Co M, Thomas SJ, Kalayanarooj S, Yoon IK, Nisalak A, Srikiatkhachorn A, Green S, Stephens HA, Gostick E, Price DA, Carrington M, ... Alter G, et al. Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells. Clinical and Experimental Immunology. PMID 26439909 DOI: 10.1111/Cei.12722 |
0.392 |
|
| 2015 |
Barouch DH, Alter G, Broge T, Linde C, Ackerman ME, Brown EP, Borducchi EN, Smith KM, Nkolola JP, Liu J, Shields J, Parenteau L, Whitney JB, Abbink P, Ng'ang'a DM, et al. Protective efficacy of adenovirus-protein vaccines against SIV challenges in rhesus monkeys. Science (New York, N.Y.). PMID 26138104 DOI: 10.1126/Science.Aab3886 |
0.427 |
|
| 2015 |
Brown EP, Normandin E, Osei-Owusu NY, Mahan AE, Chan YN, Lai JI, Vaccari M, Rao M, Franchini G, Alter G, Ackerman ME. Microscale purification of antigen-specific antibodies. Journal of Immunological Methods. PMID 26078040 DOI: 10.1016/J.Jim.2015.06.005 |
0.402 |
|
| 2015 |
Alter G, Sekaly RP. Beyond adjuvants: Antagonizing inflammation to enhance vaccine immunity. Vaccine. 33: B55-9. PMID 26022570 DOI: 10.1016/J.Vaccine.2015.03.058 |
0.378 |
|
| 2015 |
Johnson S, Eller M, Teigler JE, Maloveste SM, Schultz BT, Soghoian DZ, Lu R, Oster AF, Chenine AL, Alter G, Dittmer U, Marovich M, Robb ML, Michael NL, Bolton D, et al. Cooperativity of HIV-specific cytolytic CD4+ T cells and CD8+ T cells in control of HIV viremia. Journal of Virology. PMID 25972560 DOI: 10.1128/Jvi.00438-15 |
0.451 |
|
| 2015 |
Alter G, Barouch DH. Natural evolution of broadly neutralizing antibodies. Cell. 161: 427-8. PMID 25910199 DOI: 10.1016/J.Cell.2015.04.007 |
0.504 |
|
| 2015 |
Sciaranghella G, Wang C, Hu H, Anastos K, Merhi Z, Nowicki M, Stanczyk FZ, Greenblatt RM, Cohen M, Golub ET, Watts DH, Alter G, Young MA, Tsibris AM. CCR5 Expression Levels in HIV-Uninfected Women Receiving Hormonal Contraception. The Journal of Infectious Diseases. PMID 25895986 DOI: 10.1093/Infdis/Jiv233 |
0.404 |
|
| 2015 |
Li JZ, Arnold KB, Lo J, Dugast AS, Plants J, Ribaudo HJ, Cesa K, Heisey A, Kuritzkes DR, Lauffenburger DA, Alter G, Landay A, Grinspoon S, Pereyra F. Differential levels of soluble inflammatory markers by human immunodeficiency virus controller status and demographics. Open Forum Infectious Diseases. 2: ofu117. PMID 25884005 DOI: 10.1093/Ofid/Ofu117 |
0.451 |
|
| 2015 |
Choi I, Chung AW, Suscovich TJ, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kaewkungwal J, O'Connell RJ, Francis D, Robb ML, Michael NL, Kim JH, Alter G, Ackerman ME, Bailey-Kellogg C. Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees. Plos Computational Biology. 11: e1004185. PMID 25874406 DOI: 10.1371/Journal.Pcbi.1004185 |
0.518 |
|
| 2015 |
Chen J, Tibroni N, Sauter D, Galaski J, Miura T, Alter G, Mueller B, Haller C, Walker BD, Kirchhoff F, Brumme ZL, Ueno T, Fackler OT. Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma. Plos One. 10: e0120434. PMID 25793728 DOI: 10.1371/Journal.Pone.0120434 |
0.519 |
|
| 2015 |
Kaczmarek Michaels K, Natarajan M, Euler Z, Alter G, Viglianti G, Henderson AJ. Blimp-1, an intrinsic factor that represses HIV-1 proviral transcription in memory CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 3267-74. PMID 25710909 DOI: 10.4049/Jimmunol.1402581 |
0.452 |
|
| 2015 |
Boesch AW, Alter G, Ackerman ME. Prospects for engineering HIV-specific antibodies for enhanced effector function and half-life. Current Opinion in Hiv and Aids. 10: 160-9. PMID 25700208 DOI: 10.1097/Coh.0000000000000149 |
0.503 |
|
| 2015 |
Cohen KW, Dugast AS, Alter G, McElrath MJ, Stamatatos L. HIV-1 single-stranded RNA induces CXCL13 secretion in human monocytes via TLR7 activation and plasmacytoid dendritic cell-derived type I IFN. Journal of Immunology (Baltimore, Md. : 1950). 194: 2769-75. PMID 25667414 DOI: 10.4049/Jimmunol.1400952 |
0.491 |
|
| 2015 |
Suscovich TJ, Alter G. In situ production of therapeutic monoclonal antibodies. Expert Review of Vaccines. 14: 205-19. PMID 25578347 DOI: 10.1586/14760584.2015.1001375 |
0.338 |
|
| 2015 |
Mahan AE, Tedesco J, Dionne K, Baruah K, Cheng HD, De Jager PL, Barouch DH, Suscovich T, Ackerman M, Crispin M, Alter G. A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis. Journal of Immunological Methods. 417: 34-44. PMID 25523925 DOI: 10.1016/J.Jim.2014.12.004 |
0.403 |
|
| 2015 |
Euler Z, Alter G. Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication. Aids Research and Human Retroviruses. 31: 13-24. PMID 25385703 DOI: 10.1089/Aid.2014.0235 |
0.499 |
|
| 2015 |
Gupta PK, Godec J, Wolski D, Adland E, Yates K, Pauken KE, Cosgrove C, Ledderose C, Junger WG, Robson SC, Wherry EJ, Alter G, Goulder PJR, Klenerman P, Sharpe AH, et al. CD39 is highly up-regulated by exhausted CD8 + T cells in a mouse model of chronic infection. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1005177.G005 |
0.31 |
|
| 2014 |
Cohen K, Altfeld M, Alter G, Stamatatos L. Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection. Journal of Virology. 88: 13310-21. PMID 25210168 DOI: 10.1128/Jvi.02186-14 |
0.523 |
|
| 2014 |
Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, et al. Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome. Journal of Virology. 88: 12793-801. PMID 25165102 DOI: 10.1128/Jvi.02016-14 |
0.505 |
|
| 2014 |
Chung AW, Crispin M, Pritchard L, Robinson H, Gorny MK, Yu X, Bailey-Kellogg C, Ackerman ME, Scanlan C, Zolla-Pazner S, Alter G. Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function. Aids (London, England). 28: 2523-30. PMID 25160934 DOI: 10.1097/Qad.0000000000000444 |
0.447 |
|
| 2014 |
Cosgrove C, Berger CT, Kroy DC, Cheney PC, Ghebremichael M, Aneja J, Tomlinson M, Kim AY, Lauer GM, Alter G. Chronic HCV infection affects the NK cell phenotype in the blood more than in the liver. Plos One. 9: e105950. PMID 25148254 DOI: 10.1371/Journal.Pone.0105950 |
0.332 |
|
| 2014 |
Alter G, Ackerman ME. An antibody tag-team: driving neutralization through escape. Trends in Immunology. 35: 403-5. PMID 25131302 DOI: 10.1016/J.It.2014.07.009 |
0.503 |
|
| 2014 |
Trebicka E, Shanmugam NK, Mikhailova A, Alter G, Cherayil BJ. Effect of human immunodeficiency virus infection on plasma bactericidal activity against Salmonella enterica serovar Typhimurium. Clinical and Vaccine Immunology : Cvi. 21: 1437-42. PMID 25121777 DOI: 10.1128/Cvi.00501-14 |
0.488 |
|
| 2014 |
Dugast AS, Stamatatos L, Tonelli A, Suscovich TJ, Licht AF, Mikell I, Ackerman ME, Streeck H, Klasse PJ, Moore JP, Alter G. Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection. European Journal of Immunology. 44: 2925-37. PMID 25043633 DOI: 10.1002/Eji.201344305 |
0.561 |
|
| 2014 |
Boesch AW, Brown EP, Cheng HD, Ofori MO, Normandin E, Nigrovic PA, Alter G, Ackerman ME. Highly parallel characterization of IgG Fc binding interactions. Mabs. 6: 915-27. PMID 24927273 DOI: 10.4161/Mabs.28808 |
0.413 |
|
| 2014 |
Merino AM, Dugast AS, Wilson CM, Goepfert PA, Alter G, Kaslow RA, Tang J. KIR2DS4 promotes HIV-1 pathogenesis: new evidence from analyses of immunogenetic data and natural killer cell function. Plos One. 9: e99353. PMID 24901871 DOI: 10.1371/Journal.Pone.0099353 |
0.502 |
|
| 2014 |
Dugast AS, Chan Y, Hoffner M, Licht A, Nkolola J, Li H, Streeck H, Suscovich TJ, Ghebremichael M, Ackerman ME, Barouch DH, Alter G. Lack of protection following passive transfer of polyclonal highly functional low-dose non-neutralizing antibodies. Plos One. 9: e97229. PMID 24820481 DOI: 10.1371/Journal.Pone.0097229 |
0.474 |
|
| 2014 |
Thoens C, Berger C, Trippler M, Siemann H, Lutterbeck M, Broering R, Schlaak J, Heinemann FM, Heinold A, Nattermann J, Scherbaum N, Alter G, Timm J. KIR2DL3⁺NKG2A⁻ natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugs. Journal of Hepatology. 61: 475-81. PMID 24780303 DOI: 10.1016/J.Jhep.2014.04.020 |
0.316 |
|
| 2014 |
Schieffer M, Jessen HK, Oster AF, Pissani F, Soghoian DZ, Lu R, Jessen AB, Zedlack C, Schultz BT, Davis I, Ranasinghe S, Rosenberg ES, Alter G, Schumann RR, Streeck H. Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control. Journal of Virology. 88: 7357-66. PMID 24741089 DOI: 10.1128/Jvi.00728-14 |
0.51 |
|
| 2014 |
Chung AW, Ghebremichael M, Robinson H, Brown E, Choi I, Lane S, Dugast AS, Schoen MK, Rolland M, Suscovich TJ, Mahan AE, Liao L, Streeck H, Andrews C, Rerks-Ngarm S, ... ... Alter G, et al. Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines. Science Translational Medicine. 6: 228ra38. PMID 24648341 DOI: 10.1126/Scitranslmed.3007736 |
0.527 |
|
| 2014 |
Lai JI, Licht AF, Dugast AS, Suscovich T, Choi I, Bailey-Kellogg C, Alter G, Ackerman ME. Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers. Journal of Virology. 88: 2799-809. PMID 24352471 DOI: 10.1128/Jvi.03130-13 |
0.56 |
|
| 2014 |
Chung AW, Alter G. Dissecting the antibody constant region protective immune parameters in HIV infection Future Virology. 9: 397-414. DOI: 10.2217/Fvl.14.19 |
0.53 |
|
| 2014 |
Dugast A, Chan Y, Hoffner M, Licht A, Nkolola J, Li H, Streeck H, Suscovich TJ, Ghebremichael M, Ackerman ME, Barouch DH, Alter G. Kinetics of gp41-specific antibody titers and contribution of Fc mediated gp41 specific antibody responses following SHIV-SF162P3 challenge. Plos One. DOI: 10.1371/Journal.Pone.0097229.G005 |
0.387 |
|
| 2014 |
Chung AW, Schoen MK, Robinson H, Licht A, Tkachenko E, Smith DM, Little SJ, Richman DD, Alter G. Polyfunctional Non-neutralizing Fc-antibody Responses in Acute HIV Infection Predict Spontaneous Viral Control Aids Research and Human Retroviruses. 30. DOI: 10.1089/Aid.2014.5162.Abstract |
0.513 |
|
| 2013 |
Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, ... ... Alter G, et al. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies. Plos Pathogens. 9: e1003754. PMID 24278016 DOI: 10.1371/Journal.Ppat.1003754 |
0.492 |
|
| 2013 |
Barouch DH, Stephenson KE, Borducchi EN, Smith K, Stanley K, McNally AG, Liu J, Abbink P, Maxfield LF, Seaman MS, Dugast AS, Alter G, Ferguson M, Li W, Earl PL, et al. Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys. Cell. 155: 531-9. PMID 24243013 DOI: 10.1016/J.Cell.2013.09.061 |
0.548 |
|
| 2013 |
Ackerman ME, Alter G. Opportunities to exploit non-neutralizing HIV-specific antibody activity. Current Hiv Research. 11: 365-77. PMID 24191934 DOI: 10.2174/1570162X113116660058 |
0.556 |
|
| 2013 |
Forthal D, Hope TJ, Alter G. New paradigms for functional HIV-specific nonneutralizing antibodies. Current Opinion in Hiv and Aids. 8: 393-401. PMID 23924999 DOI: 10.1097/Coh.0B013E328363D486 |
0.532 |
|
| 2013 |
Koehler RN, Alter G, Tovanabutra S, Saathoff E, Arroyo MA, Walsh AM, Sanders-Buell EE, Maboko L, Hoelscher M, Robb ML, Michael NL, McCutchan FE, Kim JH, Kijak GH. Natural killer cell-mediated innate sieve effect on HIV-1: the impact of KIR/HLA polymorphism on HIV-1 subtype-specific acquisition in east Africa. The Journal of Infectious Diseases. 208: 1250-4. PMID 23922366 DOI: 10.1093/Infdis/Jit349 |
0.471 |
|
| 2013 |
Ackerman M, Alter G. Mapping the journey to an HIV vaccine. The New England Journal of Medicine. 369: 389-91. PMID 23883384 DOI: 10.1056/Nejmcibr1304437 |
0.531 |
|
| 2013 |
Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, et al. Association of HLA-DRB1-restricted CD4⺠T cell responses with HIV immune control. Nature Medicine. 19: 930-3. PMID 23793098 DOI: 10.1038/Nm.3229 |
0.477 |
|
| 2013 |
Malaspina A, Collins BS, Dell A, Alter G, Onami TM. Conference report: "Functional Glycomics in HIV Type 1 Vaccine Design" workshop report, Bethesda, Maryland, April 30-May 1, 2012. Aids Research and Human Retroviruses. 29: 1407-17. PMID 23767872 DOI: 10.1089/Aid.2013.0102 |
0.538 |
|
| 2013 |
Ackerman ME, Crispin M, Yu X, Baruah K, Boesch AW, Harvey DJ, Dugast AS, Heizen EL, Ercan A, Choi I, Streeck H, Nigrovic PA, Bailey-Kellogg C, Scanlan C, Alter G. Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. The Journal of Clinical Investigation. 123: 2183-92. PMID 23563315 DOI: 10.1172/Jci65708 |
0.589 |
|
| 2013 |
Ackerman ME, Dugast AS, McAndrew EG, Tsoukas S, Licht AF, Irvine DJ, Alter G. Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b. Journal of Virology. 87: 5468-76. PMID 23468489 DOI: 10.1128/Jvi.03403-12 |
0.555 |
|
| 2013 |
Alter G, Ackerman ME. What mAbs tell us about shapes: multiple roads lead to Rome. Immunity. 38: 8-9. PMID 23352219 DOI: 10.1016/J.Immuni.2013.01.003 |
0.462 |
|
| 2013 |
Hayes P, Gilmour J, von Lieven A, Gill D, Clark L, Kopycinski J, Cheeseman H, Chung A, Alter G, Dally L, Zachariah D, Lombardo A, Ackland J, Sayeed E, Jackson A, et al. Safety and immunogenicity of DNA prime and modified vaccinia ankara virus-HIV subtype C vaccine boost in healthy adults. Clinical and Vaccine Immunology : Cvi. 20: 397-408. PMID 23345581 DOI: 10.1128/Cvi.00637-12 |
0.45 |
|
| 2013 |
Sciaranghella G, Tong N, Mahan AE, Suscovich TJ, Alter G. Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infection. Aids (London, England). 27: 175-80. PMID 23135171 DOI: 10.1097/Qad.0B013E32835Bd1F0 |
0.498 |
|
| 2013 |
Barouch DH, Liu J, Peter L, Abbink P, Iampietro MJ, Cheung A, Alter G, Chung A, Dugast AS, Frahm N, McElrath MJ, Wenschuh H, Reimer U, Seaman MS, Pau MG, et al. Characterization of humoral and cellular immune responses elicited by a recombinant adenovirus serotype 26 HIV-1 Env vaccine in healthy adults (IPCAVD 001). The Journal of Infectious Diseases. 207: 248-56. PMID 23125443 DOI: 10.1093/Infdis/Jis671 |
0.472 |
|
| 2013 |
Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien J, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, ... ... Alter G, et al. Correction: The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies Plos Pathogens. 9. DOI: 10.1371/annotation/f1f8c791-61e9-45c6-a455-92c6dadf9f06 |
0.358 |
|
| 2012 |
Brown EP, Licht AF, Dugast AS, Choi I, Bailey-Kellogg C, Alter G, Ackerman ME. High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples. Journal of Immunological Methods. 386: 117-23. PMID 23023091 DOI: 10.1016/J.Jim.2012.09.007 |
0.409 |
|
| 2012 |
Archary D, Rong R, Gordon ML, Boliar S, Madiga M, Gray ES, Dugast AS, Hermanus T, Goulder PJ, Coovadia HM, Werner L, Morris L, Alter G, Derdeyn CA, Ndung'u T. Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection. Virology. 433: 410-20. PMID 22995189 DOI: 10.1016/J.Virol.2012.08.033 |
0.491 |
|
| 2012 |
Yamanaka YJ, Berger CT, Sips M, Cheney PC, Alter G, Love JC. Single-cell analysis of the dynamics and functional outcomes of interactions between human natural killer cells and target cells. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1175-84. PMID 22945136 DOI: 10.1039/C2Ib20167D |
0.336 |
|
| 2012 |
Lindqvist M, van Lunzen J, Soghoian DZ, Kuhl BD, Ranasinghe S, Kranias G, Flanders MD, Cutler S, Yudanin N, Muller MI, Davis I, Farber D, Hartjen P, Haag F, Alter G, et al. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. The Journal of Clinical Investigation. 122: 3271-80. PMID 22922259 DOI: 10.1172/Jci64314 |
0.536 |
|
| 2012 |
Carrington M, Alter G. Innate immune control of HIV. Cold Spring Harbor Perspectives in Medicine. 2: a007070. PMID 22762020 DOI: 10.1101/Cshperspect.A007070 |
0.505 |
|
| 2012 |
Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, et al. Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunology. 5: 646-57. PMID 22643849 DOI: 10.1038/Mi.2012.38 |
0.401 |
|
| 2012 |
Thobakgale CF, Fadda L, Lane K, Toth I, Pereyra F, Bazner S, Ndung'u T, Walker BD, Rosenberg ES, Alter G, Carrington M, Allen TM, Altfeld M. Frequent and strong antibody-mediated natural killer cell activation in response to HIV-1 Env in individuals with chronic HIV-1 infection. Journal of Virology. 86: 6986-93. PMID 22496218 DOI: 10.1128/Jvi.00569-12 |
0.549 |
|
| 2012 |
Moldt B, Shibata-Koyama M, Rakasz EG, Schultz N, Kanda Y, Dunlop DC, Finstad SL, Jin C, Landucci G, Alpert MD, Dugast AS, Parren PW, Nimmerjahn F, Evans DT, Alter G, et al. A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques. Journal of Virology. 86: 6189-96. PMID 22457527 DOI: 10.1128/Jvi.00491-12 |
0.541 |
|
| 2012 |
Xia Z, Liu Q, Berger CT, Keenan BT, Kaliszewska A, Cheney PC, Srivastava GP, Castillo IW, De Jager PL, Alter G. A 17q12 allele is associated with altered NK cell subsets and function. Journal of Immunology (Baltimore, Md. : 1950). 188: 3315-22. PMID 22345646 DOI: 10.4049/Jimmunol.1102775 |
0.346 |
|
| 2012 |
Ackerman ME, Dugast AS, Alter G. Emerging concepts on the role of innate immunity in the prevention and control of HIV infection. Annual Review of Medicine. 63: 113-30. PMID 22077718 DOI: 10.1146/Annurev-Med-050310-085221 |
0.565 |
|
| 2012 |
Sips M, Sciaranghella G, Diefenbach T, Dugast AS, Berger CT, Liu Q, Kwon D, Ghebremichael M, Estes JD, Carrington M, Martin JN, Deeks SG, Hunt PW, Alter G. Altered distribution of mucosal NK cells during HIV infection. Mucosal Immunology. 5: 30-40. PMID 21993602 DOI: 10.1038/Mi.2011.40 |
0.497 |
|
| 2012 |
Dugast A, Chung A, Chang Y, Licht A, Ackerman M, Alter G. Antibody subclass skewing predicts enhanced ADCC activity in both natural infection and vaccination Retrovirology. 9: 82. DOI: 10.1186/1742-4690-9-S2-P82 |
0.55 |
|
| 2012 |
Archary D, Rong R, Gordon ML, Boliar S, Gray ES, Dugast A, Hermanus T, Goulder PJ, Coovadia HM, Morris L, Alter G, Derdeyn C, Ndung'u T. Neutralizing and non-neutralizing antibody responses in HIV-1 subtype C chronically infected patients with divergent rates of disease progression Retrovirology. 9: 75. DOI: 10.1186/1742-4690-9-S2-P75 |
0.551 |
|
| 2012 |
Chung A, Dugast A, Robinson H, Chan Y, Ackerman M, Cox J, Koff W, Barouch D, Rerks-Ngarm S, Michael N, Kim J, Alter G. Vector induced skewing of antibody Fc-effector functions Retrovirology. 9: 361. DOI: 10.1186/1742-4690-9-S2-P361 |
0.538 |
|
| 2012 |
Sips M, Sciaranghella G, Tong N, Kwon D, Brouckaert P, Alter G. Natural Killer cells present in gut mucosa as potential ADCC effector cells Retrovirology. 9: 188. DOI: 10.1186/1742-4690-9-S2-P188 |
0.583 |
|
| 2012 |
Thobakgale C, Fadda L, Lane K, Toth I, Pereyra F, Bazner S, Ndung'u T, Walker B, Rosenberg E, Alter G, Carrington M, Allen T, Altfeld M. Frequent and strong antibody-mediated NK cell activation to HIV-1 Env in individuals with chronic HIV-1 infection Retrovirology. 9: 171. DOI: 10.1186/1742-4690-9-S2-P171 |
0.519 |
|
| 2012 |
Mahan A, Dionne K, Eusebio J, Alter G. Antibody effector function is regulated by a combination of adaptive and innate signals. Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O37 |
0.418 |
|
| 2012 |
Ackerman ME, Moldt B, Wyatt RT, Dugast A, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G. Corrigendum to “A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples” Journal of Immunological Methods. 376: 156. DOI: 10.1016/J.Jim.2011.12.006 |
0.342 |
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| 2011 |
McAndrew EG, Dugast AS, Licht AF, Eusebio JR, Alter G, Ackerman ME. Determining the phagocytic activity of clinical antibody samples. Journal of Visualized Experiments : Jove. e3588. PMID 22143444 DOI: 10.3791/3588 |
0.474 |
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| 2011 |
Pelak K, Need AC, Fellay J, Shianna KV, Feng S, Urban TJ, Ge D, De Luca A, Martinez-Picado J, Wolinsky SM, Martinson JJ, Jamieson BD, Bream JH, Martin MP, Borrow P, ... ... Alter G, et al. Copy number variation of KIR genes influences HIV-1 control. Plos Biology. 9: e1001208. PMID 22140359 DOI: 10.1371/Journal.Pbio.1001208 |
0.469 |
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| 2011 |
Fadda L, Alter G. KIR/HLA: genetic clues for a role of NK cells in the control of HIV. Advances in Experimental Medicine and Biology. 780: 27-36. PMID 21842362 DOI: 10.1007/978-1-4419-5632-3_3 |
0.522 |
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| 2011 |
Alter G, Heckerman D, Schneidewind A, Fadda L, Kadie CM, Carlson JM, Oniangue-Ndza C, Martin M, Li B, Khakoo SI, Carrington M, Allen TM, Altfeld M. HIV-1 adaptation to NK-cell-mediated immune pressure. Nature. 476: 96-100. PMID 21814282 DOI: 10.1038/Nature10237 |
0.524 |
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| 2011 |
Luteijn R, Sciaranghella G, van Lunzen J, Nolting A, Dugast AS, Ghebremichael MS, Altfeld M, Alter G. Early viral replication in lymph nodes provides HIV with a means by which to escape NK-cell-mediated control. European Journal of Immunology. 41: 2729-40. PMID 21630248 DOI: 10.1002/Eji.201040886 |
0.495 |
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| 2011 |
Dugast AS, Tonelli A, Berger CT, Ackerman ME, Sciaranghella G, Liu Q, Sips M, Toth I, Piechocka-Trocha A, Ghebremichael M, Alter G. Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals. Virology. 415: 160-7. PMID 21565376 DOI: 10.1016/J.Virol.2011.03.012 |
0.553 |
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| 2011 |
Alter G, Altfeld M. Mutiny or scrutiny: NK cell modulation of DC function in HIV-1 infection. Trends in Immunology. 32: 219-24. PMID 21411368 DOI: 10.1016/J.It.2011.02.003 |
0.474 |
|
| 2011 |
Berger CT, Alter G. Natural killer cells in spontaneous control of HIV infection. Current Opinion in Hiv and Aids. 6: 208-13. PMID 21399495 DOI: 10.1097/Coh.0B013E3283457798 |
0.488 |
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| 2011 |
Mikell I, Sather DN, Kalams SA, Altfeld M, Alter G, Stamatatos L. Characteristics of the earliest cross-neutralizing antibody response to HIV-1. Plos Pathogens. 7: e1001251. PMID 21249232 DOI: 10.1371/Journal.Ppat.1001251 |
0.537 |
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| 2011 |
Jost S, Reardon J, Peterson E, Poole D, Bosch R, Alter G, Altfeld M. Expansion of 2B4+ natural killer (NK) cells and decrease in NKp46+ NK cells in response to influenza. Immunology. 132: 516-26. PMID 21214542 DOI: 10.1111/J.1365-2567.2010.03394.X |
0.377 |
|
| 2011 |
Ackerman ME, Moldt B, Wyatt RT, Dugast AS, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G. A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. Journal of Immunological Methods. 366: 8-19. PMID 21192942 DOI: 10.1016/J.Jim.2010.12.016 |
0.472 |
|
| 2011 |
Alter G, Jost S, Rihn S, Reyor LL, Nolan BE, Ghebremichael M, Bosch R, Altfeld M, Lauer GM. Reduced frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance. Journal of Hepatology. 55: 278-88. PMID 21168454 DOI: 10.1016/J.Jhep.2010.11.030 |
0.36 |
|
| 2011 |
Papagno L, Alter G, Assoumou L, Murphy RL, Garcia F, Clotet B, Larsen M, Braibant M, Marcelin AG, Costagliola D, Altfeld M, Katlama C, Autran B. Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine. Aids (London, England). 25: 27-36. PMID 21076273 DOI: 10.1097/Qad.0B013E328340Fe55 |
0.49 |
|
| 2011 |
Mikell I, Sather DN, Kalams SA, Altfeld M, Alter G, Stamatatos L. Correction: Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1 Plos Pathogens. 7. DOI: 10.1371/Annotation/8B3B24B5-D4Ed-483A-B233-0A88513Ad499 |
0.496 |
|
| 2011 |
Pelak K, Need AC, Fellay J, Shianna KV, Feng S, Urban TJ, Ge D, Luca AD, Martinez-Picado J, Wolinsky SM, Martinson JJ, Jamieson BD, Bream JH, Martin MP, Borrow P, ... ... Alter G, et al. Correction: Copy Number Variation of KIR Genes Influences HIV-1 Control Plos Biology. 9. DOI: 10.1371/Annotation/7E17B146-A69C-4E83-9230-7340486D9Dc8 |
0.343 |
|
| 2011 |
Mikell I, Sather DN, Kalams S, Altfeld M, Alter G, Stamatatos L. 141 Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1 Journal of Acquired Immune Deficiency Syndromes. 56: 57. DOI: 10.1097/01.Qai.0000397327.26622.5C |
0.498 |
|
| 2010 |
Lederman MM, Alter G, Daskalakis DC, Rodriguez B, Sieg SF, Hardy G, Cho M, Anthony D, Harding C, Weinberg A, Silverman RH, Douek DC, Margolis L, Goldstein DB, Carrington M, et al. Determinants of protection among HIVâ€exposed seronegative persons: an overview. The Journal of Infectious Diseases. 202: S333-8. PMID 20887220 DOI: 10.1086/655967 |
0.468 |
|
| 2010 |
Alter G, Moody MA. The humoral response to HIV-1: new insights, renewed focus. The Journal of Infectious Diseases. 202: S315-22. PMID 20846039 DOI: 10.1086/655654 |
0.547 |
|
| 2010 |
Nolting A, Dugast AS, Rihn S, Luteijn R, Carrington MF, Kane K, Jost S, Toth I, Nagami E, Faetkenheuer G, Hartmann P, Altfeld M, Alter G. MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction. Virology. 406: 12-20. PMID 20667578 DOI: 10.1016/j.virol.2010.05.014 |
0.389 |
|
| 2010 |
Alter G, Kavanagh D, Rihn S, Luteijn R, Brooks D, Oldstone M, Van Lunzen J, Altfeld M. IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection Journal of Clinical Investigation. 120: 1905-1913. PMID 20440075 DOI: 10.1172/Jci40913 |
0.429 |
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| 2010 |
Wong AH, Williams K, Reddy S, Wilson D, Giddy J, Alter G, Ghebremichael M, Carrington MN, Ndung'u T, Walker BD, Altfeld M, Carr WH. Alterations in natural killer cell receptor profiles during HIV type 1 disease progression among chronically infected South African adults. Aids Research and Human Retroviruses. 26: 459-69. PMID 20380481 DOI: 10.1089/Aid.2009.0176 |
0.496 |
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| 2010 |
Frahm N, Rabadan R, Fuchs J, Leslie A, Liu Y, Barouch D, Ndung’u T, Alter G, Cardozo T, Chohan B, Moore P, Fellay J. Young and Early Career Investigators: Report from a Global HIV Vaccine Enterprise Working Group Nature Precedings. 5: 1-1. DOI: 10.1038/Npre.2010.4800.2 |
0.403 |
|
| 2010 |
Alter G. Role of innate immunity in the control of HIV infection International Journal of Infectious Diseases. 14: e19. DOI: 10.1016/j.ijid.2010.02.1527 |
0.404 |
|
| 2009 |
Meier A, Chang JJ, Chan ES, Pollard RB, Sidhu HK, Kulkarni S, Wen TF, Lindsay RJ, Orellana L, Mildvan D, Bazner S, Streeck H, Alter G, Lifson JD, Carrington M, et al. Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1. Nature Medicine. 15: 955-9. PMID 19597505 DOI: 10.1038/Nm.2004 |
0.471 |
|
| 2009 |
Liu Q, Sun Y, Rihn S, Nolting A, Tsoukas PN, Jost S, Cohen K, Walker B, Alter G. Matrix metalloprotease inhibitors restore impaired NK cell-mediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection. Journal of Virology. 83: 8705-12. PMID 19553339 DOI: 10.1128/Jvi.02666-08 |
0.527 |
|
| 2009 |
Alter G, Rihn S, Walter K, Nolting A, Martin M, Rosenberg ES, Miller JS, Carrington M, Altfeld M. HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection. Journal of Virology. 83: 6798-805. PMID 19386717 DOI: 10.1128/Jvi.00256-09 |
0.465 |
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| 2009 |
Alter G, Ananworanich J, Pantophlet R, Rybicki EP, Buonaguro L. Report on the AIDS Vaccine 2008 Conference. Human Vaccines. 5: 119-25. PMID 19202348 DOI: 10.4161/Hv.5.3.7557 |
0.441 |
|
| 2009 |
Alter G, Altfeld M. NK cells in HIV‐1 infection: evidence for their role in the control of HIV‐1 infection Journal of Internal Medicine. 265: 29-42. PMID 19093958 DOI: 10.1111/J.1365-2796.2008.02045.X |
0.457 |
|
| 2009 |
Wang YE, Li B, Carlson JM, Streeck H, Gladden AD, Goodman R, Schneidewind A, Power KA, Toth I, Frahm N, Alter G, Brander C, Carrington M, Walker BD, Altfeld M, et al. Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. Journal of Virology. 83: 1845-55. PMID 19036810 DOI: 10.1128/Jvi.01061-08 |
0.398 |
|
| 2009 |
Angin M, Streeck H, Wen F, Pyo A, Trocha A, Toth I, Kwon D, Pereyra F, Alter G, Altfeld M, Walker B, Addo M. P16-18. Regulatory T cell frequencies correlate with T cell activation in chronic HIV-1 infection Retrovirology. 6: 247. DOI: 10.1186/1742-4690-6-S3-P247 |
0.511 |
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| 2009 |
Luteijn R, Nolting A, Lunzen Jv, Altfeld M, Alter G. P10-11. NK Cells do not Accumulate at Sites of HIV-Replication but Show Increased Activation Retrovirology. 6: 142. DOI: 10.1186/1742-4690-6-S3-P142 |
0.43 |
|
| 2009 |
Dugast A, Tonelli A, Toth I, Piechocka-Trocha A, Alter G. P10-03. Dramatic changes in Fc-receptor expression during HIV-1 infection associated with reduced phagocytic activity during progressive HIV-1 infection Retrovirology. 6: 134. DOI: 10.1186/1742-4690-6-S3-P134 |
0.471 |
|
| 2009 |
Nolting A, Dugast A, Rihn S, Luteijn R, Carrington MF, Kane K, Jost S, Toth I, Nagami E, Faetkenheuer G, Hartmann P, Altfeld M, Alter G. P10-01. MHC Class I Chain-related Protein A Shedding in Chronic HIV-1 Infection is Associated with Profound NK Cell Dysfunction Retrovirology. 406: 12-20. DOI: 10.1186/1742-4690-6-S3-P132 |
0.488 |
|
| 2009 |
Oniangue-Ndza C, Schneidewind A, Brockman MA, Brumme ZL, Boutwell CL, Wang YE, Brumme CJ, Power KA, Gladden AD, Kemper M, Le Gall S, Streeck H, Alter G, Altfeld M, Heckerman D, et al. P09-10. Impact of CTL escape mutations in HIV-1 Nef on viral replication Retrovirology. 6: P123. DOI: 10.1186/1742-4690-6-S3-P123 |
0.485 |
|
| 2008 |
Alter G, Rihn S, Streeck H, Teigen N, Piechocka-Trocha A, Moss K, Cohen K, Meier A, Pereyra F, Walker B, Altfeld M. Ligand-independent exhaustion of killer immunoglobulin-like receptor-positive CD8+ T cells in human immunodeficiency virus type 1 infection. Journal of Virology. 82: 9668-77. PMID 18579582 DOI: 10.1128/Jvi.00341-08 |
0.457 |
|
| 2008 |
Streeck H, Brumme ZL, Anastario M, Cohen KW, Jolin JS, Meier A, Brumme CJ, Rosenberg ES, Alter G, Allen TM, Walker BD, Altfeld M. Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells. Plos Medicine. 5: e100. PMID 18462013 DOI: 10.1371/Journal.Pmed.0050100 |
0.532 |
|
| 2008 |
Meier A, Bagchi A, Sidhu HK, Alter G, Suscovich TJ, Kavanagh DG, Streeck H, Brockman MA, LeGall S, Hellman J, Altfeld M. Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands Aids. 22: 655-658. PMID 18317010 DOI: 10.1097/Qad.0B013E3282F4De23 |
0.368 |
|
| 2007 |
Lakshmanan V, Alter G, Altfeld M, Bhardwaj N. Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection. Current Opinion in Hiv and Aids. 2: 189-200. PMID 19372886 DOI: 10.1097/Coh.0B013E32810996Db |
0.499 |
|
| 2007 |
Alter G, Martin MP, Teigen N, Carr WH, Suscovich TJ, Schneidewind A, Streeck H, Waring M, Meier A, Brander C, Lifson JD, Allen TM, Carrington M, Altfeld M. Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. The Journal of Experimental Medicine. 204: 3027-36. PMID 18025129 DOI: 10.1084/Jem.20070695 |
0.514 |
|
| 2007 |
Pascal V, Yamada E, Martin MP, Alter G, Altfeld M, Metcalf JA, Baseler MW, Adelsberger JW, Carrington M, Anderson SK, McVicar DW. Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 1625-33. PMID 17641029 DOI: 10.4049/Jimmunol.179.3.1625 |
0.462 |
|
| 2007 |
Alter G, Suscovich TJ, Teigen N, Meier A, Streeck H, Brander C, Altfeld M. Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 7658-66. PMID 17548602 DOI: 10.4049/Jimmunol.178.12.7658 |
0.491 |
|
| 2007 |
Meier A, Alter G, Frahm N, Sidhu H, Li B, Bagchi A, Teigen N, Streeck H, Stellbrink HJ, Hellman J, Van Lunzen J, Altfeld M. MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded toll-like receptor ligands Journal of Virology. 81: 8180-8191. PMID 17507480 DOI: 10.1128/Jvi.00421-07 |
0.521 |
|
| 2007 |
Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M. Recognition of a defined region within p24 GAG by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles Journal of Virology. 81: 7725-7731. PMID 17494064 DOI: 10.1128/Jvi.00708-07 |
0.483 |
|
| 2007 |
Alter G, Teigen N, Ahern R, Streeck H, Meier A, Rosenberg ES, Altfeld M. Evolution of Innate and Adaptive Effector Cell Functions during Acute HIV-1 Infection The Journal of Infectious Diseases. 195: 1452-1460. PMID 17436225 DOI: 10.1086/513878 |
0.529 |
|
| 2006 |
Altfeld M, Kalife ET, Qi Y, Streeck H, Lichterfeld M, Johnston MN, Burgett N, Swartz ME, Yang A, Alter G, Yu XG, Meier A, Rockstroh JK, Allen TM, Jessen H, et al. HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8+ T cell response against HIV-1 Plos Medicine. 3: 1851-1864. PMID 17076553 DOI: 10.1371/Journal.Pmed.0030403 |
0.512 |
|
| 2006 |
Alter G, Altfeld M. NK cell function in HIV-1 infection. Current Molecular Medicine. 6: 621-629. PMID 17022732 DOI: 10.2174/156652406778195035 |
0.517 |
|
| 2006 |
Streeck H, Jessen H, Alter G, Teigen N, Waring MT, Jessen A, Stahmer I, Lunzen Jv, Lichterfeld M, Gao X, Allen TM, Carrington M, Walker BD, Rockstroh JK, Altfeld M. Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection. The Journal of Infectious Diseases. 194: 734-739. PMID 16941338 DOI: 10.1086/503811 |
0.464 |
|
| 2006 |
Alter G, Suscovich TJ, Kleyman M, Teigen N, Streeck H, Zaman MT, Meier A, Altfeld M. Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection. Aids (London, England). 20: 1549-51. PMID 16847410 DOI: 10.1097/01.Aids.0000237371.31315.48 |
0.398 |
|
| 2006 |
Bashirova AA, Bleiber G, Qi Y, Hutcheson H, Yamashita T, Johnson RC, Cheng J, Alter G, Goedert JJ, Buchbinder S, Hoots K, Vlahov D, May M, Maldarelli F, Jacobson L, et al. Consistent effects of TSG101 genetic variability on multiple outcomes of exposure to human immunodeficiency virus type 1 Journal of Virology. 80: 6757-6763. PMID 16809281 DOI: 10.1128/Jvi.00094-06 |
0.408 |
|
| 2005 |
Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, et al. De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection. Journal of Virology. 79: 12952-60. PMID 16188997 DOI: 10.1128/Jvi.79.20.12952-12960.2005 |
0.454 |
|
| 2005 |
Yu XG, Lichterfeld M, Perkins B, Kalife E, Mui S, Chen J, Cheng M, Kang W, Alter G, Brander C, Walker BD, Altfeld M. High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level. Aids (London, England). 19: 1449-56. PMID 16135897 DOI: 10.1097/01.Aids.0000183126.32077.C8 |
0.442 |
|
| 2005 |
Alter G, Teigen N, Davis BT, Addo MM, Suscovich TJ, Waring MT, Streeck H, Johnston MN, Staller KD, Zaman MT, Yu XG, Lichterfeld M, Basgoz N, Rosenberg ES, Altfeld M. Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. Blood. 106: 3366-9. PMID 16002429 DOI: 10.1182/Blood-2005-03-1100 |
0.405 |
|
| 2005 |
Altfeld M, Allen TM, Kalife ET, Frahm N, Addo MM, Mothe BR, Rathod A, Reyor LL, Harlow J, Yu XG, Perkins B, Robinson LK, Sidney J, Alter G, Lichterfeld M, et al. The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design. Journal of Virology. 79: 5000-5. PMID 15795285 DOI: 10.1128/Jvi.79.8.5000-5005.2005 |
0.421 |
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| 2005 |
Peretz Y, Alter G, Boisvert MP, Hatzakis G, Tsoukas CM, Bernard NF. Human immunodeficiency virus (HIV)-specific gamma interferon secretion directed against all expressed HIV genes: relationship to rate of CD4 decline. Journal of Virology. 79: 4908-17. PMID 15795276 DOI: 10.1128/Jvi.79.8.4908-4917.2005 |
0.687 |
|
| 2004 |
Alter G, Malenfant JM, Altfeld M. CD107a as a functional marker for the identification of natural killer cell activity Journal of Immunological Methods. 294: 15-22. PMID 15604012 DOI: 10.1016/J.Jim.2004.08.008 |
0.351 |
|
| 2004 |
Alter G, Tsoukas CM, Rouleau D, Côté P, Routy JP, Sékaly RP, Bernard NF. Assessment of longitudinal changes in HIV-specific effector activity in subjects undergoing untreated primary HIV infection. Aids (London, England). 18: 1979-89. PMID 15577619 DOI: 10.1097/00002030-200410210-00002 |
0.704 |
|
| 2004 |
Alter G, Malenfant JM, Delabre RM, Burgett NC, Yu XG, Lichterfeld M, Zaunders J, Altfeld M. Increased natural killer cell activity in viremic HIV-1 infection. Journal of Immunology. 173: 5305-5311. PMID 15470077 DOI: 10.4049/Jimmunol.173.8.5305 |
0.474 |
|
| 2004 |
Lichterfeld M, Kaufmann DE, Yu XG, Mui SK, Addo MM, Johnston MN, Cohen D, Robbins GK, Pae E, Alter G, Wurcel A, Stone D, Rosenberg ES, Walker BD, Altfeld M. Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4 + T cells Journal of Experimental Medicine. 200: 701-712. PMID 15381726 DOI: 10.1084/Jem.20041270 |
0.527 |
|
| 2004 |
Lichterfeld M, Yu XG, Waring MT, Mui SK, Johnston MN, Cohen D, Addo MM, Zaunders J, Alter G, Pae E, Strick D, Allen TM, Rosenberg ES, Walker BD, Altfeld M. HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha. Blood. 104: 487-94. PMID 15059848 DOI: 10.1182/Blood-2003-12-4341 |
0.419 |
|
| 2003 |
Alter G, Hatzakis G, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, Baril JG, Dion H, Lefebvre E, Thomas R, Côté P, Lapointe N, Routy JP, Sékaly RP, Conway B, et al. Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection. Journal of Immunology (Baltimore, Md. : 1950). 171: 477-88. PMID 12817033 DOI: 10.4049/Jimmunol.171.1.477 |
0.666 |
|
| 2002 |
Alter G, Merchant A, Tsoukas CM, Rouleau D, LeBlanc RP, Côté P, Baril JG, Thomas R, Nguyen VK, Sékaly RP, Routy JP, Bernard NF. Human immunodeficiency virus (HIV)-specific effector CD8 T cell activity in patients with primary HIV infection. The Journal of Infectious Diseases. 185: 755-65. PMID 11920293 DOI: 10.1086/339338 |
0.689 |
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