149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Majzoub K, Hafirassou ML, Meignin C, Goto A, Marzi S, Fedorova A, Verdier Y, Vinh J, Hoffmann JA, Martin F, Baumert TF, Schuster C, Imler JL. RACK1 controls IRES-mediated translation of viruses. Cell. 159: 1086-95. PMID 25416947 DOI: 10.1016/j.cell.2014.10.041  0.84
2014 Hoffmann J, Tárnoki A, Tárnoki D. Q&A: Jules Hoffmann. Fighting fit. Nature. 514: S5. PMID 25317593 DOI: 10.1038/514S5a  0.84
2014 Chtarbanova S, Lamiable O, Lee KZ, Galiana D, Troxler L, Meignin C, Hetru C, Hoffmann JA, Daeffler L, Imler JL. Drosophila C virus systemic infection leads to intestinal obstruction. Journal of Virology. 88: 14057-69. PMID 25253354 DOI: 10.1128/JVI.02320-14  0.84
2014 Tartey S, Matsushita K, Vandenbon A, Ori D, Imamura T, Mino T, Standley DM, Hoffmann JA, Reichhart JM, Akira S, Takeuchi O. Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex. The Embo Journal. 33: 2332-48. PMID 25107474 DOI: 10.15252/embj.201488447  0.84
2014 Goto A, Fukuyama H, Imler JL, Hoffmann JA. The chromatin regulator DMAP1 modulates activity of the nuclear factor κB (NF-κB) transcription factor Relish in the Drosophila innate immune response Journal of Biological Chemistry. 289: 20470-20476. PMID 24947515 DOI: 10.1074/jbc.C114.553719  0.84
2013 Fukuyama H, Verdier Y, Guan Y, Makino-Okamura C, Shilova V, Liu X, Maksoud E, Matsubayashi J, Haddad I, Spirohn K, Ono K, Hetru C, Rossier J, Ideker T, Boutros M, ... ... Hoffmann JA, et al. Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge. Proceedings of the National Academy of Sciences of the United States of America. 110: 10717-22. PMID 23749869 DOI: 10.1073/pnas.1304380110  0.84
2013 Bonnay F, Cohen-Berros E, Hoffmann M, Kim SY, Boulianne GL, Hoffmann JA, Matt N, Reichhart JM. big bang gene modulates gut immune tolerance in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 2957-62. PMID 23378635 DOI: 10.1073/pnas.1221910110  0.84
2013 Kemp C, Mueller S, Goto A, Barbier V, Paro S, Bonnay F, Dostert C, Troxler L, Hetru C, Meignin C, Pfeffer S, Hoffmann JA, Imler JL. Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila. Journal of Immunology (Baltimore, Md. : 1950). 190: 650-8. PMID 23255357 DOI: 10.4049/jimmunol.1102486  0.84
2012 Liu X, Sano T, Guan Y, Nagata S, Hoffmann JA, Fukuyama H. Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif Plos One. 7. PMID 22916150 DOI: 10.1371/journal.pone.0042725  0.84
2012 Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983. Journal of Immunology (Baltimore, Md. : 1950). 188: 5210-20. PMID 22611248  0.84
2012 Fukuyama H, Ndiaye S, Hoffmann J, Rossier J, Liuu S, Vinh J, Verdier Y. On-bead tryptic proteolysis: an attractive procedure for LC-MS/MS analysis of the Drosophila caspase 8 protein complex during immune response against bacteria. Journal of Proteomics. 75: 4610-9. PMID 22450469 DOI: 10.1016/j.jprot.2012.03.003  0.84
2011 Eleftherianos I, Won S, Chtarbanova S, Squiban B, Ocorr K, Bodmer R, Beutler B, Hoffmann JA, Imler JL. ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections. Proceedings of the National Academy of Sciences of the United States of America. 108: 12024-9. PMID 21719711 DOI: 10.1073/pnas.1108926108  0.84
2010 Muellera S, Gausson V, Vodovar N, Deddouchea S, Troxler L, Perot J, Pfeffer S, Hoffmann JA, Saleh MC, Imler JL. RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in drosophila Proceedings of the National Academy of Sciences of the United States of America. 107: 19390-19395. PMID 20978209 DOI: 10.1073/pnas.1014378107  0.84
2009 Hetru C, Hoffmann JA. NF-kappaB in the immune response of Drosophila. Cold Spring Harbor Perspectives in Biology. 1: a000232. PMID 20457557 DOI: 10.1101/cshperspect.a000232  0.84
2009 Mishima Y, Quintin J, Aimanianda V, Kellenberger C, Coste F, Clavaud C, Hetru C, Hoffmann JA, Latgé JP, Ferrandon D, Roussel A. The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors. The Journal of Biological Chemistry. 284: 28687-97. PMID 19692333 DOI: 10.1074/jbc.M109.034587  0.84
2009 Fraiture M, Baxter RH, Steinert S, Chelliah Y, Frolet C, Quispe-Tintaya W, Hoffmann JA, Blandin SA, Levashina EA. Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium. Cell Host & Microbe. 5: 273-84. PMID 19286136 DOI: 10.1016/j.chom.2009.01.005  0.84
2008 Beutler B, Hoffmann J. What infections actually are Journal of Innate Immunity. 1: 2-3. PMID 20391631 DOI: 10.1159/000143226  0.84
2008 Deddouche S, Matt N, Budd A, Mueller S, Kemp C, Galiana-Arnoux D, Dostert C, Antoniewski C, Hoffmann JA, Imler JL. The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila. Nature Immunology. 9: 1425-32. PMID 18953338 DOI: 10.1038/ni.1664  0.84
2008 Maillet F, Bischoff V, Vignal C, Hoffmann J, Royet J. The Drosophila peptidoglycan recognition protein PGRP-LF blocks PGRP-LC and IMD/JNK pathway activation. Cell Host & Microbe. 3: 293-303. PMID 18474356 DOI: 10.1016/j.chom.2008.04.002  0.84
2008 Goto A, Matsushita K, Gesellchen V, Chamy LE, Kuttenkeuler D, Takeuchi O, Hoffmann JA, Akira S, Boutros M, Reichhart JM. Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice Nature Immunology. 9: 97-104. PMID 18066067 DOI: 10.1038/ni1543  0.84
2007 Nehme NT, Liégeois S, Kele B, Giammarinaro P, Pradel E, Hoffmann JA, Ewbank JJ, Ferrandon D. A model of bacterial intestinal infections in Drosophila melanogaster. Plos Pathogens. 3: e173. PMID 18039029 DOI: 10.1371/journal.ppat.0030173  0.36
2007 Ferrandon D, Imler JL, Hetru C, Hoffmann JA. The Drosophila systemic immune response: Sensing and signalling during bacterial and fungal infections Nature Reviews Immunology. 7: 862-874. PMID 17948019 DOI: 10.1038/nri2194  0.84
2007 Beutler B, Eidenschenk C, Crozat K, Imler JL, Takeuchi O, Hoffmann JA, Akira S. Genetic analysis of resistance to viral infection Nature Reviews Immunology. 7: 753-766. PMID 17893693 DOI: 10.1038/nri2174  0.84
2007 Hoffmann J. Antifungal defense in drosophila Nature Immunology. 8: 543-545. PMID 17514202 DOI: 10.1038/ni0607-543  0.84
2007 Lemaitre B, Hoffmann J. The host defense of Drosophila melanogaster. Annual Review of Immunology. 25: 697-743. PMID 17201680 DOI: 10.1146/annurev.immunol.25.022106.141615  0.84
2007 Nehme NT, Liégeois S, Kele B, Giammarinaro P, Pradel E, Hoffmann JA, Ewbank JJ, Ferrandon D. A model of bacterial intestinal infections in Drosophila melanogaster Plos Pathogens. 3: 1694-1709. DOI: 10.1371/journal.ppat.0030173  0.84
2006 Shiao SH, Whitten MMA, Zachary D, Hoffmann JA, Levashina EA. Fz2 and cdc42 mediate melanization and actin polymerization but are dispensable for Plasmodium killing in the mosquito midgut. Plos Pathogens. 2: e133. PMID 17196037 DOI: 10.1371/journal.ppat.0020133  0.84
2006 Gottar M, Gobert V, Matskevich AA, Reichhart JM, Wang C, Butt TM, Belvin M, Hoffmann JA, Ferrandon D. Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors Cell. 127: 1425-1437. PMID 17190605 DOI: 10.1016/j.cell.2006.10.046  0.84
2006 Frolet C, Thoma M, Blandin S, Hoffmann JA, Levashina EA. Boosting NF-κB-Dependent Basal Immunity of Anopheles gambiae Aborts Development of Plasmodium berghei Immunity. 25: 677-685. PMID 17045818 DOI: 10.1016/j.immuni.2006.08.019  0.84
2006 Galiana-Arnoux D, Dostert C, Schneemann A, Hoffmann JA, Imler JL. Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila Nature Immunology. 7: 590-597. PMID 16554838 DOI: 10.1038/ni1335  0.84
2006 Bischoff V, Vignal C, Duvic B, Boneca IG, Hoffmann JA, Royet J. Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2. Plos Pathogens. 2: e14. PMID 16518472 DOI: 10.1371/journal.ppat.0020014  0.84
2006 Leclerc V, Pelte N, El Chamy L, Martinelli C, Ligoxygakis P, Hoffmann JA, Reichhart JM. Prophenoloxidase activation is not required for survival to microbial infections in Drosophila. Embo Reports. 7: 231-5. PMID 16322759 DOI: 10.1038/sj.embor.7400592  0.84
2005 Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Rämet M, et al. Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell. 123: 335-46. PMID 16239149 DOI: 10.1016/j.cell.2005.08.034  0.84
2005 Dostert C, Jouanguy E, Irving P, Troxler L, Galiana-Arnoux D, Hetru C, Hoffmann JA, Imler JL. The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila Nature Immunology. 6: 946-953. PMID 16086017 DOI: 10.1038/ni1237  0.84
2005 Irving P, Ubeda JM, Doucet D, Troxler L, Lagueux M, Zachary D, Hoffmann JA, Hetru C, Meister M. New insights into Drosophila larval haemocyte functions through genome-wide analysis. Cellular Microbiology. 7: 335-50. PMID 15679837 DOI: 10.1111/j.1462-5822.2004.00462.x  0.84
2005 Royet J, Reichhart JM, Hoffmann JA. Sensing and signaling during infection in Drosophila Current Opinion in Immunology. 17: 11-17. PMID 15653304 DOI: 10.1016/j.coi.2004.12.002  0.84
2004 Levy F, Rabel D, Charlet M, Bulet P, Hoffmann JA, Ehret-Sabatier L. Peptidomic and proteomic analyses of the systemic immune response of Drosophila. Biochimie. 86: 607-16. PMID 15556270 DOI: 10.1016/j.biochi.2004.07.007  0.84
2004 Bischoff V, Vignal C, Boneca IG, Michel T, Hoffmann JA, Royet J. Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria. Nature Immunology. 5: 1175-80. PMID 15448690 DOI: 10.1038/ni1123  0.84
2004 Imler JL, Ferrandon D, Royet J, Reichhart JM, Hetru C, Hoffmann JA. Toll-dependent and Toll-independent immune responses in Drosophila Journal of Endotoxin Research. 10: 241-246. PMID 15373968 DOI: 10.1179/096805104225005887  0.84
2004 Ferrandon D, Imler JL, Hoffmann JA. Sensing infection in Drosophila: Toll and beyond Seminars in Immunology. 16: 43-53. PMID 14751763 DOI: 10.1016/j.smim.2003.10.008  0.84
2004 Hoffmann JA. Primitive immune systems Immunological Reviews. 198: 5-9. DOI: 10.1111/j.0105-2896.2004.0134.x  0.84
2003 Gobert V, Gottar M, Matskevich AA, Rutschmann S, Royet J, Belvin M, Hoffmann JA, Ferrandon D. Dual Activation of the Drosophila Toll Pathway by Two Pattern Recognition Receptors Science. 302: 2126-2130. PMID 14684822 DOI: 10.1126/science.1085432  0.84
2003 Hoffmann JA. The immune response of Drosophila Nature. 426: 33-38. PMID 14603309 DOI: 10.1038/nature02021  0.84
2003 Thouzeau C, Le Maho Y, Froget G, Sabatier L, Le Bohec C, Hoffmann JA, Bulet P. Spheniscins, Avian β-Defensins in Preserved Stomach Contents of the King Penguin, Aptenodytes patagonicus Journal of Biological Chemistry. 278: 51053-51058. PMID 14525994 DOI: 10.1074/jbc.M306839200  0.84
2003 Weber ANR, Tauszig-Delamasure S, Hoffmann JA, Lelièvre E, Gascan H, Ray KP, Morse MA, Imler JL, Gay NJ. Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling Nature Immunology. 4: 794-800. PMID 12872120 DOI: 10.1038/ni955  0.84
2003 Hetru C, Troxler L, Hoffmann JA. Drosophila melanogaster antimicrobial defense Journal of Infectious Diseases. 187: S327-S334. PMID 12792847 DOI: 10.1086/374758  0.84
2003 Kurz CL, Chauvet S, Andrès E, Aurouze M, Vallet I, Michel GPF, Uh M, Celli J, Filloux A, De Bentzmann S, Steinmetz I, Hoffmann JA, Finlay BB, Gorvel JP, Ferrandon D, et al. Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening Embo Journal. 22: 1451-1460. PMID 12660152 DOI: 10.1093/emboj/cdg159  0.84
2003 Imler JL, Hoffmann JA. Toll signaling: The TIReless quest for specificity Nature Immunology. 4: 105-106. PMID 12555093 DOI: 10.1038/ni0203-105  0.84
2002 Kambris Z, Hoffmann JA, Imler JL, Capovilla M. Tissue and stage-specific expression of the Tolls in Drosophila embryos Gene Expression Patterns. 2: 311-317. PMID 12617819 DOI: 10.1016/S1567-133X(02)00020-0  0.84
2002 Imler JL, Hoffmann JA. Toll receptors in Drosophila: A family of molecules regulating development and immunity Current Topics in Microbiology and Immunology. 270: 63-79. PMID 12467244  0.84
2002 Ligoxygakis P, Pelte N, Ji C, Leclerc V, Duvic B, Belvin M, Jiang H, Hoffmann JA, Reichhart JM. A serpin mutant links Toll activation to melanization in the host defence of Drosophila. The Embo Journal. 21: 6330-7. PMID 12456640 DOI: 10.1093/emboj/cdf661  0.84
2002 Munier AI, Doucet D, Perrodou E, Zachary D, Meister M, Hoffmann JA, Janeway CA, Lagueux M. PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae. Embo Reports. 3: 1195-200. PMID 12446570 DOI: 10.1093/embo-reports/kvf242  0.84
2002 Duvic B, Hoffmann JA, Meister M, Royet J. Notch signaling controls lineage specification during Drosophila larval hematopoiesis. Current Biology : Cb. 12: 1923-7. PMID 12445385 DOI: 10.1016/S0960-9822(02)01297-6  0.84
2002 Naitza S, Rossé C, Kappler C, Georgel P, Belvin M, Gubb D, Camonis J, Hoffmann JA, Reichhart JM. The Drosophila immune defense against gram-negative infection requires the death protein dFADD. Immunity. 17: 575-81. PMID 12433364 DOI: 10.1016/S1074-7613(02)00454-5  0.84
2002 Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass C, Brey PT, Collins FH, Danielli A, Dimopoulos G, Hetru C, Hoa NT, Hoffmann JA, Kanzok SM, Letunic I, et al. Immunity-related genes and gene families in Anopheles gambiae. Science (New York, N.Y.). 298: 159-65. PMID 12364793 DOI: 10.1126/science.1077136  0.84
2002 Ligoxygakis P, Pelte N, Hoffmann JA, Reichhart JM. Activation of Drosophila Toll during fungal infection by a blood serine protease. Science (New York, N.Y.). 297: 114-6. PMID 12098703 DOI: 10.1126/science.1072391  0.84
2002 Gottar M, Gobert V, Michel T, Belvin M, Duyk G, Hoffmann JA, Ferrandon D, Royet J. The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein Nature. 416: 640-644. PMID 11912488 DOI: 10.1038/nature734  0.84
2002 Hoffmann JA, Reichhart JM. Drosophila innate immunity: An evolutionary perspective Nature Immunology. 3: 121-126. PMID 11812988 DOI: 10.1038/ni0202-121  0.84
2002 Tauszig-Delamasure S, Bilak H, Capovilla M, Hoffmann JA, Imler JL. Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Nature Immunology. 3: 91-97. PMID 11743586 DOI: 10.1038/ni747  0.84
2001 Michel T, Relchhart J, Hoffmann JA, Royet J. Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Nature. 414: 756-759. PMID 11742401 DOI: 10.1038/414756a  0.84
2001 Irving P, Troxler L, Heuer TS, Belvin M, Kopczynski C, Reichhart JM, Hoffmann JA, Hetru C. A genome-wide analysis of immune responses in Drosophila Proceedings of the National Academy of Sciences of the United States of America. 98: 15119-15124. PMID 11742098 DOI: 10.1073/pnas.261573998  0.84
2001 Georgel P, Naitza S, Kappler C, Ferrandon D, Zachary D, Swimmer C, Kopczynski C, Duyk G, Reichhart JM, Hoffmann JA. Drosophila Immune Deficiency (IMD) Is a Death Domain Protein that Activates Antibacterial Defense and Can Promote Apoptosis Developmental Cell. 1: 503-514. PMID 11703941 DOI: 10.1016/S1534-5807(01)00059-4  0.84
2001 Vizioli J, Bulet P, Hoffmann JA, Kafatos FC, Müller HM, Dimopoulos G. Gambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae. Proceedings of the National Academy of Sciences of the United States of America. 98: 12630-5. PMID 11606751 DOI: 10.1073/pnas.221466798  0.84
2001 Imler JL, Hoffmann JA. Toll receptors in innate immunity Trends in Cell Biology. 11: 304-311. PMID 11413042 DOI: 10.1016/S0962-8924(01)02004-9  0.84
2001 Jung AC, Criqui MC, Rutschmann S, Hoffmann JA, Ferrandon D. Microfluorometer assay to measure the expression of β-galactosidase and green fluorescent protein reporter genes in single Drosophila flies Biotechniques. 30: 594-601. PMID 11252795  0.84
2001 Lamberty M, Zachary D, Lanot R, Bordereau C, Robert A, Hoffmann JA, Bulet P. Insect immunity. Constitutive expression of a cysteine-rich antifungal and a linear antibacterial peptide in a termite insect Journal of Biological Chemistry. 276: 4085-4092. PMID 11053427 DOI: 10.1074/jbc.M002998200  0.84
2001 Alan R, Ezekowitz B, Hoffmann J. Innate immunity still blossoming Current Opinion in Immunology. 13: 53-54. DOI: 10.1016/S0952-7915(00)00181-3  0.84
2001 Dimarcq JL, Hoffmann JA. Antimicrobial peptides: Antibiotics for the future? | Peptides antimicrobiens: Les antibiotiques du futur? Biofutur. 21.  0.84
2000 Imler JL, Tauszig S, Jouanguy E, Forestier C, Hoffmann JA. LPS-induced immune response in Drosophila Journal of Endotoxin Research. 6: 459-462. PMID 11521071 DOI: 10.1179/096805100101532423  0.84
2000 Imler JL, Hoffmann JA. Toll and Toll-like proteins: An ancient family of receptors signaling infection Reviews in Immunogenetics. 2: 294-304. PMID 11256741  0.84
2000 Tzou P, Ohresser S, Ferrandon D, Capovilla M, Reichhart JM, Lemaitre B, Hoffmann JA, Imler JL. Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia. Immunity. 13: 737-48. PMID 11114385  0.84
2000 Lagueux M, Perrodou E, Levashina EA, Capovilla M, Hoffmann JA. Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila Proceedings of the National Academy of Sciences of the United States of America. 97: 11427-11432. PMID 11027343  0.84
2000 Rutschmann S, Jung AC, Zhou R, Silverman N, Hoffmann JA, Ferrandon D. Role of Drosophila IKKγ in a Toll-independent antibacterial immune response Nature Immunology. 1: 342-347. PMID 11017107  0.84
2000 Tauszig S, Jouanguy E, Hoffmann JA, Imler JL. Toll-related receptors and the control of antimicrobial peptide expression in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 97: 10520-5. PMID 10973475 DOI: 10.1073/pnas.180130797  0.84
2000 Rutschmann S, Jung AC, Hetru C, Reichhart JM, Hoffmann JA, Ferrandon D. The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila Immunity. 12: 569-580. PMID 10843389  0.84
2000 Meister M, Hetru C, Hoffmann JA. The antimicrobial host defense of Drosophila. Current Topics in Microbiology and Immunology. 248: 17-36. PMID 10793472  0.84
2000 Basset A, Khush RS, Braun A, Gardan L, Boccard F, Hoffmann JA, Lemaitre B. The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response. Proceedings of the National Academy of Sciences of the United States of America. 97: 3376-81. PMID 10725405 DOI: 10.1073/pnas.070357597  0.84
2000 Imler JL, Hoffmann JA. Signaling mechanisms in the antimicrobial host defense of Drosophila. Current Opinion in Microbiology. 3: 16-22. PMID 10679426 DOI: 10.1016/S1369-5274(99)00045-4  0.84
2000 Vizioli J, Bulet P, Charlet M, Lowenberger C, Blass C, Müller HM, Dimopoulos G, Hoffmann J, Kafatos FC, Richman A. Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae. Insect Molecular Biology. 9: 75-84. PMID 10672074 DOI: 10.1046/j.1365-2583.2000.00164.x  0.84
2000 Hetru C, Letellier L, Oren Z, Hoffmann JA, Shai Y. Androctonin, a hydrophilic disulphide-bridged non-haemolytic anti-microbial peptide: a plausible mode of action. The Biochemical Journal. 345: 653-64. PMID 10642525 DOI: 10.1042/0264-6021:3450653  0.84
1999 Levashina EA, Langley E, Green C, Gubb D, Ashburner M, Hoffmann JA, Reichhart JM. Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. Science (New York, N.Y.). 285: 1917-9. PMID 10489372 DOI: 10.1126/science.285.5435.1917  0.84
1999 Manfruelli P, Reichhart JM, Steward R, Hoffmann JA, Lemaitre B. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF. The Embo Journal. 18: 3380-91. PMID 10369678 DOI: 10.1093/emboj/18.12.3380  0.84
1999 Hoffmann JA, Kafatos FC, Janeway CA, Ezekowitz RA. Phylogenetic perspectives in innate immunity. Science (New York, N.Y.). 284: 1313-8. PMID 10334979 DOI: 10.1126/science.284.5418.1313  0.84
1999 Lamberty M, Ades S, Uttenweiler-Joseph S, Brookhart G, Bushey D, Hoffmann JA, Bulet P. Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity. The Journal of Biological Chemistry. 274: 9320-6. PMID 10092609 DOI: 10.1074/jbc.274.14.9320  0.84
1999 Lowenberger CA, Smartt CT, Bulet P, Ferdig MT, Severson DW, Hoffmann JA, Christensen BM. Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti. Insect Molecular Biology. 8: 107-18. PMID 9927179  0.84
1999 Lowenberger CA, Kamal S, Chiles J, Paskewitz S, Bulet P, Hoffmann JA, Christensen BM. Mosquito-Plasmodium interactions in response to immune activation of the vector. Experimental Parasitology. 91: 59-69. PMID 9920043 DOI: 10.1006/expr.1999.4350  0.84
1998 Dimarcq JL, Bulet P, Hetru C, Hoffmann J. Cysteine-rich antimicrobial peptides in invertebrates Biopolymers - Peptide Science Section. 47: 465-477. PMID 10333738 DOI: 10.1002/(SICI)1097-0282(1998)47:6<465::AID-BIP5>3.0.CO;2-#  0.84
1998 Braun A, Hoffmann JA, Meister M. Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes. Proceedings of the National Academy of Sciences of the United States of America. 95: 14337-42. PMID 9826701 DOI: 10.1073/pnas.95.24.14337  0.84
1998 Uttenweiler-Joseph S, Moniatte M, Lagueux M, Van Dorsselaer A, Hoffmann JA, Bulet P. Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study. Proceedings of the National Academy of Sciences of the United States of America. 95: 11342-7. PMID 9736738 DOI: 10.1073/pnas.95.19.11342  0.84
1998 Bulet P, Uttenweiler-Joseph S, Moniatte M, Van Dorsselaer A, Hoffmann JA. Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study. Journal of Protein Chemistry. 17: 528-9. PMID 9723735  0.84
1998 Taguchi S, Bulet P, Hoffmann JA. A novel insect defensin from the ant Formica rufa. Biochimie. 80: 343-6. PMID 9672756 DOI: 10.1016/S0300-9084(98)80078-3  0.84
1998 Shahabuddin M, Fields I, Bulet P, Hoffmann JA, Miller LH. Plasmodium gallinaceum: differential killing of some mosquito stages of the parasite by insect defensin. Experimental Parasitology. 89: 103-12. PMID 9603495 DOI: 10.1006/expr.1998.4212  0.84
1998 Nicolas E, Reichhart JM, Hoffmann JA, Lemaitre B. In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila. The Journal of Biological Chemistry. 273: 10463-9. PMID 9553105 DOI: 10.1074/jbc.273.17.10463  0.84
1998 Ferrandon D, Jung AC, Criqui M, Lemaitre B, Uttenweiler-Joseph S, Michaut L, Reichhart J, Hoffmann JA. A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. The Embo Journal. 17: 1217-27. PMID 9482719 DOI: 10.1093/emboj/17.5.1217  0.84
1998 Bulet P, Uttenweiler-Joseph S, Moniatte M, Van Dorsselaer A, Hoffmann JA. Differential Display of Peptides Induced during the Immune Response of Drosophila: A Matrix-Assisted Laser Desorption lonization Time-of-Flight Mass Spectrometry Study Protein Journal. 17: 528-529.  0.84
1997 Dimarcq JL, Imler JL, Lanot R, Ezekowitz RA, Hoffmann JA, Janeway CA, Lagueux M. Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression. Insect Biochemistry and Molecular Biology. 27: 877-86. PMID 9474784 DOI: 10.1016/S0965-1748(97)00072-6  0.84
1997 Lemaitre B, Reichhart JM, Hoffmann JA. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proceedings of the National Academy of Sciences of the United States of America. 94: 14614-9. PMID 9405661 DOI: 10.1073/pnas.94.26.14614  0.84
1997 Meister M, Lemaitre B, Hoffmann JA. Antimicrobial peptide defense in Drosophila. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 1019-26. PMID 9394624 DOI: 10.1002/bies.950191112  0.84
1997 Hoffmann JA. Immune responsiveness in vector insects Proceedings of the National Academy of Sciences of the United States of America. 94: 11152-11153. PMID 9326575 DOI: 10.1073/pnas.94.21.11152  0.84
1996 Ehret-Sabatier L, Loew D, Goyffon M, Fehlbaum P, Hoffmann JA, Van Dorsselaer A, Bulet P. Characterization of novel cysteine-rich antimicrobial peptides from scorpion blood Journal of Biological Chemistry. 271: 29537-29544. PMID 8939880 DOI: 10.1074/jbc.271.47.29537  0.84
1996 Barillas-Mury C, Charlesworth A, Gross I, Richman A, Hoffmann JA, Kafatos FC. Immune factor Gambif1, a new rel family member from the human malaria vector, Anopheles gambiae. The Embo Journal. 15: 4691-701. PMID 8887560  0.84
1996 Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 86: 973-83. PMID 8808632 DOI: 10.1016/S0092-8674(00)80172-5  0.84
1996 Richman AM, Bulet P, Hetru C, Barillas-Mury C, Hoffmann JA, Kafalos FC. Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA. Insect Molecular Biology. 5: 203-10. PMID 8799739  0.84
1996 Hoffmann JA, Reichhart JM, Hetru C. Innate immunity in higher insects Current Opinion in Immunology. 8: 8-13. PMID 8729440 DOI: 10.1016/S0952-7915(96)80098-7  0.84
1996 Charlet M, Chernysh S, Philippe H, Hetru C, Hoffmann JA, Bulet P. Innate immunity: Isolation of several cysteine-rich antimicrobial peptides from the blood of a mollusc, Mytilus edulis Journal of Biological Chemistry. 271: 21808-21813. PMID 8702979 DOI: 10.1074/jbc.271.36.21808  0.84
1996 Lowenberger CA, Ferdig MT, Bulet P, Khalili S, Hoffmann JA, Christensen BM. Aedes aegypti: induced antibacterial proteins reduce the establishment and development of Brugia malayi. Experimental Parasitology. 83: 191-201. PMID 8682188 DOI: 10.1006/expr.1996.0066  0.84
1996 Gross I, Georgel P, Kappler C, Reichhart JM, Hoffmann JA. Drosophila immunity: A comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin Nucleic Acids Research. 24: 1238-1245. PMID 8614625 DOI: 10.1093/nar/24.7.1238  0.84
1996 Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA. Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides Proceedings of the National Academy of Sciences of the United States of America. 93: 1221-1225. PMID 8577744 DOI: 10.1073/pnas.93.3.1221  0.84
1996 Ezekowitz RAB, Hoffmann JA. Innate immunity - Editorial overview Current Opinion in Immunology. 8: 1-2. DOI: 10.1016/S0952-7915(96)80096-3  0.84
1995 Lemaitre B, Meister M, Govind S, Georgel P, Steward R, Reichhart JM, Hoffmann JA. Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. The Embo Journal. 14: 536-45. PMID 7859742  0.84
1995 Bulet P, Hegy G, Lambert J, Van Dorsselaer A, Hoffmann JA, Hetru C. Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity Biochemistry. 34: 7394-7400. PMID 7779781  0.84
1995 Hoffmann JA. Innate immunity of insects Current Opinion in Immunology. 7: 4-10. PMID 7772280 DOI: 10.1016/0952-7915(95)80022-0  0.84
1995 Cornet B, Bonmatin JM, Hetru C, Hoffmann JA, Ptak M, Vovelle F. Refined three-dimensional solution structure of insect defensin A Structure. 3: 435-448. PMID 7663941 DOI: 10.1016/S0969-2126(01)00177-0  0.84
1995 Lowenberger C, Bulet P, Charlet M, Hetru C, Hodgeman B, Christensen BM, Hoffmann JA. Insect immunity: isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti. Insect Biochemistry and Molecular Biology. 25: 867-73. PMID 7633471 DOI: 10.1016/0965-1748(95)00043-U  0.84
1995 Lemaitre B, Kromer-Metzger E, Michaut L, Nicolas E, Meister M, Georgel P, Reichhart JM, Hoffmann JA. A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense. Proceedings of the National Academy of Sciences of the United States of America. 92: 9465-9. PMID 7568155 DOI: 10.1073/pnas.92.21.9465  0.84
1995 Georgel P, Kappler C, Langley E, Gross I, Nicolas E, Reichhart Jm, Hoffmann JA. Drosophila immunity. A sequence homologous to mammalian interferon consensus response element enhances the activity of the diptericin promoter Nucleic Acids Research. 23: 1140-1145. PMID 7537872 DOI: 10.1093/nar/23.7.1140  0.84
1994 Dimarcq JL, Hoffmann D, Meister M, Bulet P, Lanot R, Reichhart JM, Hoffmann JA. Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity. European Journal of Biochemistry / Febs. 221: 201-9. PMID 8168509  0.84
1994 Cociancich S, Dupont A, Hegy G, Lanot R, Holder F, Hetru C, Hoffmann JA, Bulet P. Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus Biochemical Journal. 300: 567-575. PMID 8002963  0.84
1994 Meister M, Braun A, Kappler C, Reichhart JM, Hoffmann JA. Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter. The Embo Journal. 13: 5958-66. PMID 7813433  0.84
1994 Fehlbaum P, Bulet P, Michaut L, Lagueux M, Broekaert WF, Hetru C, Hoffmann JA. Insect immunity: Septic injury of drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Journal of Biological Chemistry. 269: 33159-33163. PMID 7806546  0.84
1994 Cociancich S, Bulet P, Hetru C, Hoffmann JA. The inducible antibacterial peptides of insects Parasitology Today. 10: 132-139. DOI: 10.1016/0169-4758(94)90260-7  0.84
1994 Michaut L, Fehlbaum P, Bulet P, Lagueux M, Hétru C, Hoffmann JA. G2.6 Structural characterization and gene cloning of an immune inducible putative 5 kDa protease inhibitor Developmental and Comparative Immunology. 18: S123. DOI: 10.1016/0145-305X(94)90172-4  0.84
1994 Langley E, Kappler C, Georgel P, Lemaitre B, Meister M, Reichhart JM, Hoffmann JA. G2.5 Characterization of transactivating factors involved in the bacteria-induced expression of the diptericin gene in Drosophila Developmental and Comparative Immunology. 18: S123. DOI: 10.1016/0145-305X(94)90171-6  0.84
1993 Hoffmann JA, Hetru C, Reichhart JM. The humoral antibacterial response of Drosophila Febs Letters. 325: 63-66. PMID 8513894 DOI: 10.1016/0014-5793(93)81414-U  0.84
1993 Kappler C, Meister M, Lagueux M, Gateff E, Hoffmann JA, Reichhart JM. Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila. The Embo Journal. 12: 1561-8. PMID 8467806  0.84
1993 Bulet P, Dimarcq JL, Hetru C, Lagueux M, Charlet M, Hegy G, Van Dorsselaer A, Hoffmann JA. A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution. The Journal of Biological Chemistry. 268: 14893-7. PMID 8325867  0.84
1993 Reichhart JM, Georgel P, Meister M, Lemaitre B, Kappler C, Hoffmann JA. Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 316: 1218-24. PMID 8062131  0.84
1993 Cociancich S, Ghazi A, Hetru C, Hoffmann JA, Letellier L. Insect defensin, an inducible antibacterial peptide, forms voltage-dependent channels in Micrococcus luteus Journal of Biological Chemistry. 268: 19239-19245. PMID 7690029  0.84
1993 Georgel P, Meister M, Kappler C, Lemaitre B, Reichhart JM, Hoffmann JA. Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements. Biochemical and Biophysical Research Communications. 197: 508-17. PMID 7505569 DOI: 10.1006/bbrc.1993.2508  0.84
1992 Bulet P, Cociancich S, Reuland M, Sauber F, Bischoff R, Hegy G, Van Dorsselaer A, Hetru C, Hoffmann JA. A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata) European Journal of Biochemistry. 209: 977-984. PMID 1425705 DOI: 10.1111/j.1432-1033.1992.tb17371.x  0.84
1992 Hoffmann JA, Hetru C. Insect defensins: inducible antibacterial peptides Immunology Today. 13: 411-415. PMID 1418378 DOI: 10.1016/0167-5699(92)90092-L  0.84
1992 Bonmatin JM, Bonnat JL, Gallet X, Vovelle F, Ptak M, Reichhart JM, Hoffmann JA, Keppi E, Legrain M, Achstetter T. Two-dimensional1H NMR study of recombinant insect defensin A in water: Resonance assignments, secondary structure and global folding Journal of Biomolecular Nmr. 2: 235-256. PMID 1392568 DOI: 10.1007/BF01875319  0.84
1992 Reichhart JM, Meister M, Dimarcq JL, Zachary D, Hoffmann D, Ruiz C, Richards G, Hoffmann JA. Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter. The Embo Journal. 11: 1469-77. PMID 1373375  0.84
1992 Hoffmann JA, Dimarcq JL, Bulet P. Inducible antibacterial peptides of insects | LES PEPTIDES ANTIBACTERIENS INDUCTIBLES DES INSECTES Medecine/Sciences. 8: 432-439.  0.84
1991 Hoffmann JA, Joosse J. Chinless wonders New Biologist. 3: 336-340. PMID 2065018  0.84
1991 Lepage P, Bitsch F, Roecklin D, Keppi E, Dimarcq JL, Reichhart JM, Hoffmann JA, Roitsch C, Van Dorsselaer A. Determination of disulfide bridges in natural and recombinant insect defensin A European Journal of Biochemistry. 196: 735-742. PMID 2013293  0.84
1991 Hetru C, Li KW, Bulet P, Lagueux M, Hoffmann JA. Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta migratoria European Journal of Biochemistry. 201: 495-499. PMID 1935945  0.84
1991 Bulet P, Cociancich S, Dimarcq JL, Lambert J, Reichhart JM, Hoffmann D, Hetru C, Hoffmann JA. Insect Immunity: Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family Journal of Biological Chemistry. 266: 24520-24525. PMID 1761552  0.84
1991 Dolle F, Hetru C, Roussel JP, Rousseau B, Sobrio F, Luu B, Hoffmann JA. Synthesis of a tritiated 3-dehydroecdysteroid putative precursor of ecdysteroid biosynthesis in Locusta migratoria Tetrahedron. 47: 7067-7080. DOI: 10.1016/S0040-4020(01)96161-7  0.84
1990 Dimarcq JL, Zachary D, Hoffmann JA, Hoffmann D, Reichhart JM. Insect immunity: Expression of the two major inducible antibacterial peptides, defensin diptericin, in phormia terranovae Embo Journal. 9: 2507-2515. PMID 2369900  0.84
1990 Hoffmann JA, Hoffmann D. The inducible antibacterial peptides of dipteran insects Research in Immunology. 141: 910-918. PMID 2129211 DOI: 10.1016/0923-2494(90)90192-2  0.84
1990 Wicker C, Reichhart JM, Hoffmann D, Hultmark D, Samakovlis C, Hoffmann JA. Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides. The Journal of Biological Chemistry. 265: 22493-8. PMID 2125051  0.84
1990 Hoffmann D, Hoffmann JA. Cellular and molecular aspects of insect immunity Research in Immunology. 141: 895-896. PMID 2100018  0.84
1990 Lagueux M, Lwoff L, Meister M, Goltzené F, Hoffmann JA. cDNAs from neurosecretory cells of brains of Locusta migratoria (Insecta, Orthoptera) encoding a novel member of the superfamily of insulins. European Journal of Biochemistry / Febs. 187: 249-54. PMID 1688797 DOI: 10.1111/j.1432-1033.1990.tb15302.x  0.84
1990 Frédéric D, Christine K, Charles H, Bernard R, Michéle C, Bang L, Hoffmann JA. Synthesis of high specific activity [3H2-1,2]-7-dehydrocholesterol. Conversion to ecdysone in follicle cells of locusta (Insects) Tetrahedron. 46: 5305-5316. DOI: 10.1016/S0040-4020(01)87837-6  0.84
1989 Reichhart JM, Essrich M, Dimarcq JL, Hoffmann D, Hoffmann JA, Lagueux M. Insect immunity. Isolation of cDNA clones corresponding to diptericin, an inducible antibacterial peptide from Phormia terranovae (Diptera). Transcriptional profiles during immunization European Journal of Biochemistry. 182: 423-427. PMID 2544427  0.84
1974 Hoffmann JA, Koolman J, Karlson P, Joly P. Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera) General and Comparative Endocrinology. 22: 90-97. PMID 4814737 DOI: 10.1016/0016-6480(74)90091-4  0.84
1973 Koolman J, Hoffmann JA, Karlson P. Sulphate esters as inactivation products of ecdysone in Locusta migratoria Hoppe Seyler's Z.Physiol.Chem.. 354: 1043-1048. PMID 4609886 DOI: 10.1515/bchm2.1973.354.2.1043  0.84
1970 Hoffmann JA, Porte A, Joly P. [On the localization of phenol-oxidase activity in coagulocytes of Locusta migratoria L. (Orthoptera)]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 270: 629-31. PMID 4985478  0.84
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