Flossie Wong-Staal - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Molecular Biology, Microbiology Biology, Pathology

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang CY, Wong WW, Tsai HC, Chen YH, Kuo BS, Lynn S, Blazkova J, Clarridge KE, Su HW, Lin CY, Tseng FC, Lai A, Yang FH, Lin CH, Tseng W, ... ... Wong-Staal F, et al. Effect of Anti-CD4 Antibody UB-421 on HIV-1 Rebound after Treatment Interruption. The New England Journal of Medicine. 380: 1535-1545. PMID 30995373 DOI: 10.1056/Nejmoa1802264  0.478
2015 Rowe IA, Tully DC, Armstrong MJ, Parker R, Guo K, Barton D, Morse GD, Venuto CS, Ogilvie CB, Hedegaard DL, McKelvy JF, Wong-Staal F, Allen TM, Balfe P, McKeating JA, et al. Effect of scavenger receptor BI antagonist ITX5061 in patients with hepatitis C virus infection undergoing liver transplantation. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 26437376 DOI: 10.1002/Lt.24349  0.3
2012 Zhu H, Wong-Staal F, Lee H, Syder A, McKelvy J, Schooley RT, Wyles DL. Evaluation of ITX 5061, a scavenger receptor B1 antagonist: resistance selection and activity in combination with other hepatitis C virus antivirals. The Journal of Infectious Diseases. 205: 656-62. PMID 22279172 DOI: 10.1093/Infdis/Jir802  0.302
2011 Brimacombe CL, Grove J, Meredith LW, Hu K, Syder AJ, Flores MV, Timpe JM, Krieger SE, Baumert TF, Tellinghuisen TL, Wong-Staal F, Balfe P, McKeating JA. Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission. Journal of Virology. 85: 596-605. PMID 20962076 DOI: 10.1128/Jvi.01592-10  0.355
2010 Wong-Staal F, Syder AJ, McKelvy JF. Targeting HCV entry for development of therapeutics. Viruses. 2: 1718-33. PMID 21994703 DOI: 10.3390/V2081718  0.357
2009 Zhou D, Zhang J, Wang C, Bliesath JR, He Q, Yu D, Li-He Z, Wong-Staal F. A method for detecting and preventing negative RNA interference in preparation of lentiviral vectors for siRNA delivery. Rna (New York, N.Y.). 15: 732-40. PMID 19244361 DOI: 10.1261/Rna.985209  0.407
2009 Yang JP, Zhou D, Wong-Staal F. Screening of small-molecule compounds as inhibitors of HCV entry. Methods in Molecular Biology (Clifton, N.J.). 510: 295-304. PMID 19009270 DOI: 10.1007/978-1-59745-394-3_22  0.306
2008 He QS, Tang H, Zhang J, Truong K, Wong-Staal F, Zhou D. Comparisons of RNAi approaches for validation of human RNA helicase A as an essential factor in hepatitis C virus replication. Journal of Virological Methods. 154: 216-9. PMID 18782589 DOI: 10.1016/J.Jviromet.2008.08.005  0.382
2008 Ke N, Ma H, Diedrich G, Chionis J, Liu G, Yu DH, Wong-Staal F, Li QX. Biochemical characterization of genetic mutations of GPR56 in patients with bilateral frontoparietal polymicrogyria (BFPP). Biochemical and Biophysical Research Communications. 366: 314-20. PMID 18042463 DOI: 10.1016/J.Bbrc.2007.11.071  0.315
2007 Zhang J, Wang C, Ke N, Bliesath J, Chionis J, He QS, Li QX, Chatterton JE, Wong-Staal F, Zhou D. A more efficient RNAi inducible system for tight regulation of gene expression in mammalian cells and xenograft animals. Rna (New York, N.Y.). 13: 1375-83. PMID 17616554 DOI: 10.1261/Rna.520707  0.383
2007 Ke N, Sundaram R, Liu G, Chionis J, Fan W, Rogers C, Awad T, Grifman M, Yu D, Wong-Staal F, Li QX. Orphan G protein-coupled receptor GPR56 plays a role in cell transformation and tumorigenesis involving the cell adhesion pathway. Molecular Cancer Therapeutics. 6: 1840-50. PMID 17575113 DOI: 10.1158/1535-7163.Mct-07-0066  0.364
2006 Zhou D, He QS, Wang C, Zhang J, Wong-Staal F. RNA interference and potential applications. Current Topics in Medicinal Chemistry. 6: 901-11. PMID 16787283 DOI: 10.2174/156802606777303630  0.395
2006 Yu DH, Fan W, Liu G, Nguy V, Chatterton JE, Long S, Ke N, Meyhack B, Bruengger A, Brachat A, Wong-Staal F, Li QX. PHTS, a novel putative tumor suppressor, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway. Experimental Cell Research. 312: 865-76. PMID 16413018 DOI: 10.1016/J.Yexcr.2005.12.006  0.328
2005 Yu DH, Chatterton JE, Bliesath JR, Sundaram R, Ke N, Nguy V, Meyhack B, Wong-Staal F, Li QX. A 96-well surrogate survival assay coupled with a special short interfering RNA vector for assessing cancer gene targets with enhanced signal/noise ratio and its utility in HTS for cancer therapeutic targets. Assay and Drug Development Technologies. 3: 401-11. PMID 16180995 DOI: 10.1089/Adt.2005.3.401  0.345
2004 Ma H, Thibault J, Lu Y, Whiting C, Long S, Lindwall G, Bennett K, Truong L, Aimes RT, Wong-Staal F. The development and applications of nonradioactive plate-formatted DNA-binding assay for Ku70/80, a multifunctional DNA-binding protein complex. Assay and Drug Development Technologies. 2: 483-95. PMID 15671646 DOI: 10.1089/Adt.2004.2.483  0.329
2004 Ke N, Claassen G, Yu DH, Albers A, Fan W, Tan P, Grifman M, Hu X, Defife K, Nguy V, Meyhack B, Brachat A, Wong-Staal F, Li QX. Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis. Cancer Research. 64: 8208-12. PMID 15548686 DOI: 10.1158/0008-5472.Can-04-2134  0.331
2004 Waninger S, Kuhen K, Hu X, Chatterton JE, Wong-Staal F, Tang H. Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approach. Journal of Virology. 78: 12829-37. PMID 15542635 DOI: 10.1128/Jvi.78.23.12829-12837.2004  0.603
2004 Tetsuka T, Uranishi H, Sanda T, Asamitsu K, Yang JP, Wong-Staal F, Okamoto T. RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator. European Journal of Biochemistry / Febs. 271: 3741-51. PMID 15355351 DOI: 10.1111/J.1432-1033.2004.04314.X  0.406
2004 Hu X, Hipolito S, Lynn R, Abraham V, Ramos S, Wong-Staal F. Relative gene-silencing efficiencies of small interfering RNAs targeting sense and antisense transcripts from the same genetic locus. Nucleic Acids Research. 32: 4609-17. PMID 15333693 DOI: 10.1093/Nar/Gkh790  0.399
2004 Morris KV, Gilbert J, Wong-Staal F, Gasmi M, Looney DJ. Transduction of cell lines and primary cells by FIV-packaged HIV vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 181-90. PMID 15272479 DOI: 10.1016/J.Ymthe.2004.03.019  0.736
2004 Kan-Mitchell J, Bisikirska B, Wong-Staal F, Schaubert KL, Bajcz M, Bereta M. The HIV-1 HLA-A2-SLYNTVATL is a help-independent CTL epitope. Journal of Immunology (Baltimore, Md. : 1950). 172: 5249-61. PMID 15100263 DOI: 10.4049/Jimmunol.172.9.5249  0.416
2004 Smith WA, Schurter BT, Wong-Staal F, David M. Arginine methylation of RNA helicase a determines its subcellular localization. The Journal of Biological Chemistry. 279: 22795-8. PMID 15084609 DOI: 10.1074/Jbc.C300512200  0.32
2004 Chatterton JE, Hu X, Wong-Staal F. Ribozymes in gene identification, target validation and drug discovery Drug Discovery Today: Targets. 3: 10-17. DOI: 10.1016/S1741-8372(04)02382-5  0.324
2003 Gruber A, Chen I, Kuhen KL, Wheat JC, Law P, Wong-Staal F. Generation of dendritic cells from lentiviral vector-transduced CD34+ cells from HIV+ donors Journal of Medical Virology. 70: 183-186. PMID 12696103 DOI: 10.1002/Jmv.10376  0.458
2003 Rhoades K, Wong-Staal F. Inverse Genomics as a powerful tool to identify novel targets for the treatment of neurodegenerative diseases. Mechanisms of Ageing and Development. 124: 125-32. PMID 12618015 DOI: 10.1016/S0047-6374(02)00175-6  0.357
2003 Gasmi M, Wong-Staal F. Virus-based vectors for gene expression in mammalian cells: Lentiviruses New Comprehensive Biochemistry. 38: 251-264. DOI: 10.1016/S0167-7306(03)38015-9  0.52
2002 Yang JP, Reddy TR, Truong KT, Suhasini M, Wong-Staal F. Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K. Oncogene. 21: 7187-94. PMID 12370808 DOI: 10.1038/Sj.Onc.1205759  0.382
2002 Tang H, Peng T, Wong-Staal F. Novel technologies for studying virus-host interaction and discovering new drug targets for HCV and HIV. Current Opinion in Pharmacology. 2: 541-7. PMID 12324256 DOI: 10.1016/S1471-4892(02)00201-1  0.446
2002 Cheng L, Chaidhawangul S, Wong-Staal F, Gilbert J, Poeschla E, Toyoguchi M, El-Bradey M, Bergeron-Lynn G, Soules KA, Freeman WR. Human immunodeficiency virus type 2 (HIV-2) vector-mediated in vivo gene transfer into adult rabbit retina. Current Eye Research. 24: 196-201. PMID 12221527 DOI: 10.1076/Ceyr.24.3.196.8302  0.495
2002 Xu W, Zhang Y, Yeh LY, Ruprecht CR, Wong-Staal F, McFadden BA, Reddy TR, Ruprecht RM. One-step, highly efficient site-directed mutagenesis by toxic protein selection Biotechniques. 32: 1266-1270. PMID 12074156 DOI: 10.2144/02326St01  0.34
2002 Reddy TR, Suhasini M, Xu W, Yeh LY, Yang JP, Wu J, Artzt K, Wong-Staal F. A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication. The Journal of Biological Chemistry. 277: 5778-84. PMID 11741900 DOI: 10.1074/Jbc.M106836200  0.565
2002 Cortés MJ, Wong-Staal F, Lama J. Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells. The Journal of Biological Chemistry. 277: 1770-9. PMID 11704677 DOI: 10.1074/Jbc.M109807200  0.478
2001 Gilbert JR, Wong-Staal F. HIV-2 and SIV vector systems. Somatic Cell and Molecular Genetics. 26: 83-98. PMID 12465463 DOI: 10.1023/A:1021026730034  0.498
2001 Kuwabara T, Warashina M, Sano M, Tang H, Wong-Staal F, Munekata E, Taira K. Recognition of engineered tRNAs with an extended 3′ end byexportin-t (Xpo-t) and transport of tRNA-attached ribozymes to the cytoplasm in somatic cells Biomacromolecules. 2: 1229-1242. PMID 11777397 DOI: 10.1021/Bm0101062  0.339
2001 Krüger M, Beger C, Welch PJ, Barber JR, Manns MP, Wong-Staal F. Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation. Molecular and Cellular Biology. 21: 8357-64. PMID 11713272 DOI: 10.1128/Mcb.21.24.8357-8364.2001  0.375
2001 Gruber A, Wheat JC, Kuhen KL, Looney DJ, Wong-Staal F. Differential effects of HIV-1 protease inhibitors on dendritic cell immunophenotype and function. The Journal of Biological Chemistry. 276: 47840-3. PMID 11602580 DOI: 10.1074/Jbc.M105582200  0.457
2001 Gruber A, Looney DJ, Ibanez M, Wong-Staal F. Altered immunophenotype of dendritic cells generated from HIV infected subjects. Immunology Letters. 78: 209-11. PMID 11578697 DOI: 10.1016/S0165-2478(01)00246-2  0.427
2001 Krüger M, Beger C, Welch PJ, Barber JR, Wong-Staal F. C-SPACE (cleavage-specific amplification of cDNA ends): a novel method of ribozyme-mediated gene identification. Nucleic Acids Research. 29: E94. PMID 11574696 DOI: 10.1093/Nar/29.19.E94  0.359
2001 Yang JP, Tang H, Reddy TR, Wong-Staal F. Mapping the Functional Domains of HAP95, a Protein that Binds RNA Helicase A and Activates the Constitutive Transport Element of Type D Retroviruses Journal of Biological Chemistry. 276: 30694-30700. PMID 11402034 DOI: 10.1074/Jbc.M102809200  0.478
2001 Buchschacher GL, Wong-Staal F. Approaches to gene therapy for human immunodeficiency virus infection Human Gene Therapy. 12: 1013-1019. PMID 11399224 DOI: 10.1089/104303401750214249  0.49
2001 Beger C, Pierce LN, Kruger M, Marcusson EG, Robbins JM, Welcsh P, Welch PJ, Welte K, King MC, Barber JR, Wong-Staal F. Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach. Proceedings of the National Academy of Sciences of the United States of America. 98: 130-5. PMID 11136250 DOI: 10.1073/Pnas.98.1.130  0.354
2001 Krueger M, Beger C, Welch PJ, Barber JR, Manns MP, Wong-Staal F. C-space (cleavage-specific amplification of CDNA Ends): a novel method of ribozyme-mediated gene identification developed on hepatitis C virus RNA Journal of Hepatology. 34: 129. DOI: 10.1016/S0168-8278(01)81344-1  0.377
2000 Feng Y, Leavitt M, Tritz R, Duarte E, Kang D, Mamounas M, Gilles P, Wong-Staal F, Kennedy S, Merson J, Yu M, Barber JR. Inhibition of CCR5-dependent HIV-1 infection by hairpin ribozyme gene therapy against CC-chemokine receptor 5. Virology. 276: 271-8. PMID 11040119 DOI: 10.1006/Viro.2000.0536  0.519
2000 Wong-Staal F, Buchschacher GL. Gene therapy and the two faces of HIV Gene Therapy. 7: 1351-1352. PMID 10981660 DOI: 10.1038/Sj.Gt.3301267  0.434
2000 Reddy TR, Xu WD, Wong-Staal F. General effect of Sam68 on Rev/Rex regulated expression of complex retroviruses Oncogene. 19: 4071-4074. PMID 10962565 DOI: 10.1038/Sj.Onc.1203749  0.479
2000 Reddy TR, Tang H, Xu W, Wong-Staal F. Sam68, RNA helicase A and Tap cooperate in the post-transcriptional regulation of human immunodeficiency virus and type D retroviral mRNA Oncogene. 19: 3570-3575. PMID 10951562 DOI: 10.1038/Sj.Onc.1203676  0.561
2000 Gruber A, Kan-Mitchell J, Kuhen KL, Mukai T, Wong-Staal F. Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro Blood. 96: 1327-1333. PMID 10942374 DOI: 10.1182/Blood.V96.4.1327.H8001327_1327_1333  0.46
2000 Tang H, Wong-Staal F. Specific interaction between RNA helicase A and Tap, two cellular proteins that bind to the constitutive transport element of type D retrovirus Journal of Biological Chemistry. 275: 32694-32700. PMID 10924507 DOI: 10.1074/Jbc.M003933200  0.459
2000 Kruger M, Beger C, Li QX, Welch PJ, Tritz R, Leavitt M, Barber JR, Wong-Staal F. Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach. Proceedings of the National Academy of Sciences of the United States of America. 97: 8566-71. PMID 10900014 DOI: 10.1073/Pnas.97.15.8566  0.365
2000 Welch PJ, Marcusson EG, Li QX, Beger C, Krüger M, Zhou C, Leavitt M, Wong-Staal F, Barber JR. Identification and validation of a gene involved in anchorage-independent cell growth control using a library of randomized hairpin ribozymes. Genomics. 66: 274-83. PMID 10873382 DOI: 10.1006/Geno.2000.6230  0.385
2000 Buchschacher GL, Wong-Staal F. Development of lentiviral vectors for gene therapy for human diseases Blood. 95: 2499-2504. PMID 10753827 DOI: 10.1182/Blood.V95.8.2499.008K35_2499_2504  0.418
2000 Westberg C, Yang JP, Tang H, Reddy TR, Wong-Staal F. A novel shuttle protein binds to RNA helicase A and activates the retroviral constitutive transport element Journal of Biological Chemistry. 275: 21396-21401. PMID 10748171 DOI: 10.1074/Jbc.M909887199  0.704
1999 Tang H, Kuhen KL, Wong-Staal F. Lentivirus replication and regulation Annual Review of Genetics. 33: 133-170. PMID 10690406 DOI: 10.1146/Annurev.Genet.33.1.133  0.527
1999 Andäng M, Hinkula J, Hotchkiss G, Larsson S, Britton S, Wong-Staal F, Wahren B, Ährlund-Richter L. Dose-response resistance to HIV-1/MulV pseudotype virus ex vivo in a hairpin ribozyme transgenic mouse model Proceedings of the National Academy of Sciences of the United States of America. 96: 12749-12753. PMID 10535994 DOI: 10.1073/pnas.96.22.12749  0.444
1999 Krüger M, Beger C, Wong-Staal F. Use of ribozymes to inhibit gene expression Methods in Enzymology. 306: 207-225. PMID 10432456 DOI: 10.1016/S0076-6879(99)06014-0  0.522
1999 Reddy TR, Xu W, Mau JK, Goodwin CD, Suhasini M, Tang H, Frimpong K, Rose DW, Wong-Staal F. Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev. Nature Medicine. 5: 635-42. PMID 10371501 DOI: 10.1038/9479  0.567
1999 Zhang A, Geisler SC, Smith AD, Resnick DA, Li ML, Wang CY, Looney DJ, Wong-Staal F, Arnold E, Arnold GF. A disulfide-bound HIV-1 V3 loop sequence on the surface of human rhinovirus 14 induces neutralizing responses against HIV-1. Biological Chemistry. 380: 365-74. PMID 10223339 DOI: 10.1515/Bc.1999.048  0.368
1999 Tang H, McDonald D, Middlesworth T, Hope TJ, Wong-Staal F. The carboxyl terminus of RNA helicase a contains a bidirectional nuclear transport domain Molecular and Cellular Biology. 19: 3540-3550. PMID 10207077 DOI: 10.1128/Mcb.19.5.3540  0.382
1999 Law P, Lane TA, Gervaix A, Looney D, Schwarz L, Young D, Ramos S, Wong-Staal F, Recktenwald D, Ho AD. Mobilization of peripheral blood progenitor cells for human immunodeficiency virus-infected individuals. Experimental Hematology. 27: 147-54. PMID 9923453 DOI: 10.1016/S0301-472X(98)00023-X  0.336
1999 Li J, Tang H, Mullen TM, Westberg C, Reddy TR, Rose DW, Wong-Staal F. A role for RNA helicase A in post-transcriptional regulation of HIV type 1 Proceedings of the National Academy of Sciences of the United States of America. 96: 709-714. PMID 9892698 DOI: 10.1073/Pnas.96.2.709  0.738
1999 Poeschla EM, Wong-Staal F. 21 Advances in Gene Therapy for HIV and Other Viral Infections Cold Spring Harbor Monograph Archive. 36: 573-606. DOI: 10.1101/087969528.36.573  0.432
1998 Li X, Mukai T, Young D, Frankel S, Law P, Wong-Staal F. Transduction of CD34+ cells by a vesicular stomach virus protein G (VSV-G) pseudotyped HIV-1 vector: Stable gene expression in progeny cells, including dendritic cells Journal of Human Virology. 1: 346-352. PMID 10195262  0.373
1998 Wong-Staal F, Poeschla EM, Looney DJ. A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA. Human Gene Therapy. 9: 2407-25. PMID 9829540 DOI: 10.1089/Hum.1998.9.16-2407  0.503
1998 Welch PJ, Barber JR, Wong-Staal F. Expression of ribozymes in gene transfer systems to modulate target RNA levels. Current Opinion in Biotechnology. 9: 486-96. PMID 9821277 DOI: 10.1016/S0958-1669(98)80034-7  0.435
1998 Yang Q, Mamounas M, Yu G, Kennedy S, Leaker B, Merson J, Wong-Staal F, Yu M, Barber JR. Development of novel cell surface CD34-targeted recombinant adenoassociated virus vectors for gene therapy. Human Gene Therapy. 9: 1929-37. PMID 9741431 DOI: 10.1089/Hum.1998.9.13-1929  0.37
1998 Radaelli A, Kraus G, Schmidt A, Badel P, Mcclure J, Hu SL, Morton W, De Giuli Morghen C, Wong-Staal F, Looney D. Genetic variation in a human immunodeficiency virus type 2 live-virus Macaca nemestrina vaccine model Journal of Virology. 72: 7871-7884. PMID 9733824 DOI: 10.1128/Jvi.72.10.7871-7884.1998  0.486
1998 Poeschla E, Gilbert J, Li X, Huang S, Ho A, Wong-Staal F. Identification of a human immunodeficiency virus type 2 (HIV-2) encapsidation determinant and transduction of nondividing human cells by HIV- 2-based lentivirus vectors Journal of Virology. 72: 6527-6536. PMID 9658096 DOI: 10.1128/Jvi.72.8.6527-6536.1998  0.554
1998 Li X, Gervaix A, Kang D, Law P, Spector SA, Ho AD, Wong-Staal F. Gene therapy targeting cord blood-derived CD34+ cells from HIV-exposed infants: Preclinical studies Gene Therapy. 5: 233-239. PMID 9578843  0.359
1998 Corbeau P, Wong-Staal F. Anti-HIV effects of HIV vectors Virology. 243: 268-274. PMID 9568026 DOI: 10.1006/Viro.1998.9089  0.508
1998 Corbeau P, Kraus G, Wong-Staal F. Transduction of human macrophages using a stable HIV-1/HIV-2-derived gene delivery system Gene Therapy. 5: 99-104. PMID 9536270 DOI: 10.1038/Sj.Gt.3300563  0.516
1998 Looney DJ, McClure J, Kent SJ, Radaelli A, Kraus G, Schmidt A, Steffy K, Greenberg P, Hu SL, Morton WR, Wong-Staal F. A minimally replicative HIV-2 live-virus vaccine protects M. nemestrina from disease after HIV-2(287) challenge. Virology. 242: 150-60. PMID 9501043 DOI: 10.1006/Viro.1997.8992  0.509
1998 Poeschla EM, Wong-Staal F, Looney DJ. Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors. Nature Medicine. 4: 354-7. PMID 9500613 DOI: 10.1038/Nm0398-354  0.44
1998 Kraus G, Radaelli A, Talbott R, Leavitt M, Schmidt A, Badel P, Bartz C, Morton W, Wong-Staal F, Looney DJ. Characterization of a molecular clone of HIV type 2 infectious for Macaca nemestrina. Aids Research and Human Retroviruses. 14: 65-77. PMID 9453253 DOI: 10.1089/Aid.1998.14.65  0.519
1998 Reddy TR, Li X, Jones Y, Ellisman MH, Ching GY, Liem RK, Wong-Staal F. Specific interaction of HTLV tax protein and a human type IV neuronal intermediate filament protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 702-7. PMID 9435256 DOI: 10.1073/Pnas.95.2.702  0.366
1997 Gervaix A, Schwarz L, Law P, Ho AD, Looney D, Lane T, Wong-Staal F. Gene therapy targeting peripheral blood CD34+ hematopoietic stem cells of HIV-infected individuals. Human Gene Therapy. 8: 2229-38. PMID 9449376 DOI: 10.1089/Hum.1997.8.18-2229  0.491
1997 Reddy TR, Tang H, Li X, Wong-Staal F. Functional interaction of the HTLV-1 transactivator Tax with activating transcription factor-4 (ATF4) Oncogene. 14: 2785-2792. PMID 9190894 DOI: 10.1038/Sj.Onc.1201119  0.413
1997 Tang H, Gaietta GM, Fischer WH, Ellisman MH, Wong-Staal F. A cellular cofactor for the constitutive transport element of type D retrovirus. Science (New York, N.Y.). 276: 1412-5. PMID 9162007 DOI: 10.1126/Science.276.5317.1412  0.458
1997 Tang H, Xu Y, Wong-Staal F. Identification and purification of cellular proteins that specifically interact with the RNA constitutive transport elements from retrovirus D Virology. 228: 333-339. PMID 9123840 DOI: 10.1006/Viro.1996.8407  0.546
1997 Gervaix A, West D, Leoni LM, Richman DD, Wong-Staal F, Corbeil J. A new reporter cell line to monitor HIV infection and drug susceptibility in vitro Proceedings of the National Academy of Sciences of the United States of America. 94: 4653-4658. PMID 9114046 DOI: 10.1073/Pnas.94.9.4653  0.448
1997 Gervaix A, Li X, Kraus G, Wong-Staal F. Multigene antiviral vectors inhibit diverse human immunodeficiency virus type 1 clades Journal of Virology. 71: 3048-3053. PMID 9060665 DOI: 10.1128/Jvi.71.4.3048-3053.1997  0.596
1997 Wong-Staal F. Strategies for genetic intervention of HIV replication Faseb Journal. 11.  0.44
1996 Corbeau P, Kraus G, Wong-Staal F. Efficient gene transfer by a human immunodeficiency virus type 1 (HIV-1)-derived vector utilizing a stable HIV packaging cell line Proceedings of the National Academy of Sciences of the United States of America. 93: 14070-14075. PMID 8943062 DOI: 10.1073/Pnas.93.24.14070  0.531
1996 Poeschla E, Corbeau P, Wong-Staal F. Development of HIV vectors for anti-HIV gene therapy Proceedings of the National Academy of Sciences of the United States of America. 93: 11395-11399. PMID 8876146 DOI: 10.1073/Pnas.93.21.11395  0.525
1996 Leavitt MC, Yu M, Wong-Staal F, Looney DJ. Ex vivo transduction and expansion of CD4+ lymphocytes from HIV + donors: prelude to a ribozyme gene therapy trial. Gene Therapy. 3: 599-606. PMID 8818647  0.386
1996 Wong-Staal F. Development of ribozyme gene therapy for HIV infection Antibiotics and Chemotherapy. 48: 226-232. PMID 8726529 DOI: 10.1159/000425181  0.451
1996 Reddy RT, Achim CL, Sirko DA, Tehranchi S, Kraus FG, Wong-Staal F, Wiley CA. Sequence analysis of the V3 loop in brain and spleen of patients with HIV encephalitis. Aids Research and Human Retroviruses. 12: 477-82. PMID 8679302 DOI: 10.1089/Aid.1996.12.477  0.311
1996 Yamada O, Kraus G, Sargueil B, Yu Q, Burke JM, Wong-Staal F. Conservation of a hairpin ribozyme sequence in HIV-1 is required for efficient viral replication Virology. 220: 361-366. PMID 8661387 DOI: 10.1006/Viro.1996.0324  0.469
1996 Yamada O, Kraus G, Luznik L, Yu M, Wong-Staal F. A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1 Journal of Virology. 70: 1596-1601. PMID 8627679 DOI: 10.1128/Jvi.70.3.1596-1601.1996  0.572
1996 Xu J, Luznik L, Wong-Staal F, Gill GN. Hormone receptor regulation of the human immunodeficiency virus type 1 and type 2 long terminal repeats Journal of Biomedical Science. 3: 323-331. DOI: 10.1007/Bf02257962  0.52
1996 Heusch M, Kraus G, Johnson P, Wong-Staal F. Intracellular immunization against SIV(mac) utilizing a hairpin ribozyme Virology. 216: 241-244. DOI: 10.1006/Viro.1996.0055  0.508
1995 Luznik L, Kraus G, Guatelli J, Richman D, Wong-Staal F. Tat-independent replication of human immunodeficiency viruses Journal of Clinical Investigation. 95: 328-332. PMID 7814633 DOI: 10.1172/Jci117660  0.538
1995 Reddy TR, Kraus G, Yamada O, Looney DJ, Suhasini M, Wong-Staal F. Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants. Journal of Virology. 69: 3549-53. PMID 7745702 DOI: 10.1128/Jvi.69.6.3549-3553.1995  0.534
1995 Mamounas M, Looney DJ, Talbott R, Wong-Staal F. An infectious chimeric human immunodeficiency virus type 2 (HIV-2) expressing the HIV-1 principal neutralizing determinant. Journal of Virology. 69: 6424-9. PMID 7666543 DOI: 10.1128/Jvi.69.10.6424-6429.1995  0.511
1995 Reddy TR, Kraus G, Suhasini M, Leavitt MC, Wong-Staal F. Identification and mapping of inhibitory sequences in the human immunodeficiency virus type 2 vif gene Journal of Virology. 69: 5167-5170. PMID 7609089 DOI: 10.1128/Jvi.69.8.5167-5170.1995  0.561
1995 Reddy TR, Suhasini M, Rappaport J, Looney DJ, Kraus G, Wong-Staal F. Molecular cloning and characterization of a TAR-binding nuclear factor from T cells. Aids Research and Human Retroviruses. 11: 663-9. PMID 7576925 DOI: 10.1089/Aid.1995.11.663  0.705
1995 Luznik L, Martone ME, Kraus G, Zhang Y, Xu Y, Ellisman MH, Wong-Staal F. Localization of human immunodeficiency virus Rev in transfected and virus-infected cells. Aids Research and Human Retroviruses. 11: 795-804. PMID 7546906 DOI: 10.1089/Aid.1995.11.795  0.573
1995 Yu M, Leavitt MC, Maruyama M, Yamada O, Young D, Ho AD, Wong-Staal F. Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 92: 699-703. PMID 7531339 DOI: 10.1073/Pnas.92.3.699  0.399
1995 Poeschla EM, Wong-Staal F. Gene therapy and HIV disease Aids Clinical Review. 1-45. PMID 7488553  0.328
1995 Wong-Staal F. Ribozyme gene therapy for HIV infection Intracellular immunization of lymphocytes and CD34+ cells with an anti-HIV-1 ribozyme gene Advanced Drug Delivery Reviews. 17: 363-368. DOI: 10.1016/0169-409X(95)00072-F  0.533
1994 Poeschla E, Wong-Staal F. Molecular biology of HIV: challenges for the second decade Aids Research and Human Retroviruses. 10: 111-112. PMID 8198866 DOI: 10.1089/Aid.1994.10.111  0.433
1994 Yamada O, Kraus G, Leavitt MC, Yu M, Wong-Staal F. Activity and cleavage site specificity of an Anti-HIV-1 hairpin ribozyme in human T cells Virology. 205: 121-126. PMID 7975207 DOI: 10.1006/Viro.1994.1626  0.552
1994 Morgan RA, Baler-Bitterlich G, Ragheb JA, Wong-Staal F, Gallo RC, Anderson WF. Further evaluation of soluble CD4 as an anti-HIV type 1 gene therapy: demonstration of protection of primary human peripheral blood lymphocytes from infection by HIV type 1. Aids Research and Human Retroviruses. 10: 1507-15. PMID 7888205 DOI: 10.1089/Aid.1994.10.1507  0.525
1994 Leavitt MC, Yu M, Yamada O, Kraus G, Looney D, Poeschla E, Wong-Staal F. Transfer of an anti-HIV-1 ribozyme gene into primary human lymphocytes Human Gene Therapy. 5: 1115-1120. PMID 7833371 DOI: 10.1089/Hum.1994.5.9-1115  0.537
1994 Poeschla E, Wong-Staal F. Antiviral and anticancer ribozymes Current Opinion in Oncology. 6: 601-606. PMID 7827172 DOI: 10.1097/00001622-199411000-00012  0.503
1994 Yamada O, Yu M, Yee JK, Kraus G, Looney D, Wong-Staal F. Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1. Gene Therapy. 1: 38-45. PMID 7584058  0.478
1994 Yu M, Poeschla E, Wong-Staal F. Progress towards gene therapy for HIV-infection Gene Therapy. 1: 13-26. PMID 7584055  0.422
1993 Talbott R, Kraus G, Looney D, Wong-Staal F. Mapping the determinants of human immunodeficiency virus 2 for infectivity, replication efficiency, and cytopathicity Proceedings of the National Academy of Sciences of the United States of America. 90: 4226-4230. PMID 8483938 DOI: 10.1073/Pnas.90.9.4226  0.495
1993 Steffy KR, Wong-Staal F. Transdominant inhibition of wild-type human immunodeficiency virus type 2 replication by an envelope deletion mutant Journal of Virology. 67: 1854-1859. PMID 8445714 DOI: 10.1128/Jvi.67.4.1854-1859.1993  0.457
1993 Li G, Lisziewicz J, Sun D, Zon G, Daefler S, Wong-Staal F, Gallo RC, Klotman ME. Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element. Journal of Virology. 67: 6882-8. PMID 8411393 DOI: 10.1128/Jvi.67.11.6882-6888.1993  0.49
1993 Yu M, Ojwang J, Yamada O, Hampel A, Rapapport J, Looney D, Wong-Staal F. A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 90: 6340-6344. PMID 8327516 DOI: 10.1073/Pnas.90.13.6340  0.542
1993 Hofman FM, Wright AD, Dohadwala MM, Wong-Staal F, Walker SM. Exogenous tat protein activates human endothelial cells Blood. 82: 2774-2780. PMID 7693046  0.385
1992 Steffy KR, Kraus G, Looney DJ, Wong-Staal F. Role of the fusogenic peptide sequence in syncytium induction and infectivity of human immunodeficiency virus type 2. Journal of Virology. 66: 4532-5. PMID 1602558 DOI: 10.1128/Jvi.66.7.4532-4535.1992  0.445
1992 Sadaie MR, Kalyanaraman VS, Mukopadhayaya R, Tschachler E, Gallo RC, Wong-Staal F. Biological characterization of noninfectious HIV-1 particles lacking the envelope protein. Virology. 187: 604-11. PMID 1546456 DOI: 10.1016/0042-6822(92)90462-X  0.607
1992 Looney DJ, Li M, Walfield A, Hosein B, Badel P, Wang CY, Wong-Staal F. Type-specific and cross-reactive neutralizing antisera against HIV elicited by V3-peptide heptalysine octomers. Aids Research and Human Retroviruses. 8: 1381. PMID 1466961 DOI: 10.1089/Aid.1992.8.1381  0.382
1992 Wong-Staal F, Haseltine WA. Regulatory genes of human immunodeficiency viruses Molecular Genetic Medicine. 2: 189-219. PMID 1458225 DOI: 10.1016/B978-0-12-462002-5.50012-1  0.386
1992 Ojwang JO, Hampel A, Looney DJ, Wong-Staal F, Rappaport J. Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme. Proceedings of the National Academy of Sciences of the United States of America. 89: 10802-6. PMID 1438280 DOI: 10.1073/Pnas.89.22.10802  0.703
1991 Vaishnav YN, Vaishnav M, Wong-Staal F. Identification and characterization of a nuclear factor that specifically binds to the Rev response element (RRE) of human immunodeficiency virus type 1 (HIV-1) New Biologist. 3: 142-150. PMID 2065010  0.403
1991 Steffy K, Wong-Staal F. Genetic regulation of human immunodeficiency virus Microbiological Reviews. 55: 193-205. PMID 1886517 DOI: 10.1128/Mmbr.55.2.193-205.1991  0.529
1991 Vaishnav YN, Wong-Staal F. The biochemistry of AIDS Annual Review of Biochemistry. 60: 577-630. PMID 1883204 DOI: 10.1146/Annurev.Bi.60.070191.003045  0.497
1991 Ivanoff LA, Looney DJ, McDanal C, Morris JF, Wong-Staal F, Langlois AJ, Petteway SR, Matthews TJ. Alteration of HIV-1 infectivity and neutralization by a single amino acid replacement in the V3 loop domain Aids Research and Human Retroviruses. 7: 595-603. PMID 1768461 DOI: 10.1089/aid.1991.7.595  0.358
1991 Klotman ME, Kim S, Buchbinder A, DeRossi A, Baltimore D, Wong-Staal F. Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes Proceedings of the National Academy of Sciences of the United States of America. 88: 5011-5015. PMID 1711215 DOI: 10.1073/Pnas.88.11.5011  0.533
1991 Josephs SF, Ablashi DV, Salahuddin SZ, Jagodzinski LL, Wong-Staal F, Gallo RC. Identification of the human herpesvirus 6 glycoprotein H and putative large tegument protein genes. Journal of Virology. 65: 5597-604. PMID 1654455 DOI: 10.1128/Jvi.65.10.5597-5604.1991  0.421
1990 Okamoto T, Benter T, Josephs SF, Reza Sadaie M, Wong-Staal F. Transcriptional activation from the long-terminal repeat of human immunodeficiency virus in Vitro Virology. 177: 606-614. PMID 2371770 DOI: 10.1016/0042-6822(90)90526-W  0.467
1990 Morgan RA, Looney DJ, Muenchau DD, Wong-Staal F, Gallo RC, Anderson WF. Retroviral vectors expressing soluble CD4: a potential gene therapy for AIDS. Aids Research and Human Retroviruses. 6: 183-91. PMID 2328156 DOI: 10.1089/Aid.1990.6.183  0.546
1990 Zagury JF, Josephs SF, Agius G, Nicol I, Willer A, Kalyanaraman VS, Zagury D, Wong-Staal F, Gallo RC. In vitro characterization of a biologically active molecular clone of HIV-2NIH-Z containing a nef deletion and expressing a full-length transmembrane protein. Aids Research and Human Retroviruses. 6: 1079-85. PMID 2265026 DOI: 10.1089/Aid.1990.6.1079  0.525
1990 Daefler S, Klotman ME, Wong-Staal F. Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA Proceedings of the National Academy of Sciences of the United States of America. 87: 4571-4575. PMID 2191294  0.405
1990 Ensoli B, Barillari G, Salahuddin SZ, Gallo RC, Wong-Staal F. Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature. 345: 84-6. PMID 2184372 DOI: 10.1038/345084A0  0.606
1990 Chowdhury M, Taylor JP, Tada H, Rappaport J, Wong-Staal F, Amini S, Khalili K. Regulation of the human neurotropic virus promoter by JCV-T antigen and HIV-1 tat protein. Oncogene. 5: 1737-42. PMID 2178236  0.319
1990 Tada H, Rappaport J, Lashgari M, Amini S, Wong-Staal F, Khalili K. Trans-activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 3479-83. PMID 2159152 DOI: 10.1073/Pnas.87.9.3479  0.697
1990 Franchini G, Markham P, Ghard E, Fargnoli K, Keubaruwa S, Jagodzinski L, Robert-Guroff M, Lusso P, Ford G, Wong-Staal F, Gallo RC. Persistent infection of rhesus macaques with a molecular clone of human immunodeficiency virus type 2: Evidence of minimal genetic drift and low pathogenetic effects Journal of Virology. 64: 4462-4467. PMID 2117071  0.357
1990 Sadaie MR, Tschachler E, Valerie K, Rosenberg Felber MBK, Pavlakis GN, Klotman ME, Wong-Staal F. Activation of tat-defective human immunodeficiency virus by ultraviolet light New Biologist. 2: 479-486. PMID 1981148  0.397
1990 Looney DJ, Hayashi S, Nicklas M, Redfield RR, Broder S, Wong-Staal F, Mitsuya H. Differences in the interaction of HIV-1 and HIV-2 with CD4. Journal of Acquired Immune Deficiency Syndromes. 3: 649-57. PMID 1693676  0.407
1990 Wong-Staal F. Reply to the letter to the editor in Methods in Molecular and Cellular Biology, volume 2, number 1, 1990, pages 1-4: Suppression of the chloramphenicol acetyltransferase (CAT) expression-silencer by human immunodeficiency virus type 1 (HIV-1)-derived TAT product Methods in Molecular and Cellular Biology. 2: 43.  0.403
1989 Lee SJ, Hu W, Fisher AG, Looney DJ, Kao VF, Mitsuya H, Ratner L, Wong-Staal F. Role of the carboxy-terminal portion of the HIV-1 transmembrane protein in viral transmission and cytopathogenicity. Aids Research and Human Retroviruses. 5: 441-9. PMID 2788444 DOI: 10.1089/Aid.1989.5.441  0.405
1989 Okamoto T, Matsuyama T, Mori S, Hamamoto Y, Kobayashi N, Yamamoto N, Josephs SF, Wong-Staal F, Shimotohno K. Augmentation of human immunodeficiency virus type 1 gene expression by tumor necrosis factor α Aids Research and Human Retroviruses. 5: 131-138. PMID 2713164  0.412
1989 Sadaie MR, Benaissa ZN, Cullen BR, Wong-Staal F. Human immunodeficiency virus type 1 rev protein as a negative trans-regulator Dna. 8: 669-674. PMID 2693023 DOI: 10.1089/dna.1.1989.8.669  0.429
1989 Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, Wong-Staal F, Gallo RC. AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects. Science (New York, N.Y.). 243: 223-6. PMID 2643161 DOI: 10.1126/Science.2643161  0.438
1989 Yourno J, Fisher AG, Looney DJ, Gallo RC, Wong-Staal F. A recombinant clone of HIV-1 preferentially transmitted in normal peripheral blood mononuclear cells. Aids Research and Human Retroviruses. 5: 565-75. PMID 2575398 DOI: 10.1089/Aid.1989.5.565  0.497
1989 Ensoli B, Lusso P, Schachter F, Josephs SF, Rappaport J, Negro F, Gallo RC, Wong-Staal F. Human herpes virus-6 increases HIV-1 expression in co-infected T cells via nuclear factors binding to the HIV-1 enhancer. The Embo Journal. 8: 3019-27. PMID 2573513 DOI: 10.1002/J.1460-2075.1989.Tb08452.X  0.569
1989 Wong-Staal F. HIV gene regulation and pathogenesis Cancer Detection and Prevention. 14: 295-298. PMID 2559802  0.463
1989 Colombini S, Arya SK, Reitz MS, Jagodzinski L, Beaver B, Wong-Staal F. Structure of simian immunodeficiency virus regulatory genes Proceedings of the National Academy of Sciences of the United States of America. 86: 4813-4817. PMID 2544874 DOI: 10.1073/pnas.86.13.4813  0.351
1989 McDonald JF, Josephs SF, Wong-Staal F, Strand DJ. HIV-1 expression is posttranscriptionally repressed in Drosophila cells Aids Research and Human Retroviruses. 5: 79-85. PMID 2541751 DOI: 10.1089/Aid.1989.5.79  0.459
1989 Bosch ML, Earl PL, Fargnoli K, Picciafuoco S, Giombini F, Wong-Staal F, Franchini G. Identification of the fusion peptide of primate immunodeficiency viruses Science. 244: 694-697. PMID 2541505  0.353
1989 Matsukura M, Zon G, Shinozuka K, Robert-Guroff M, Shimada T, Stein CA, Mitsuya H, Wong-Staal F, Cohen JS, Broder S. Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 4244-8. PMID 2471199 DOI: 10.1073/Pnas.86.11.4244  0.484
1989 Lusso P, Ensoli B, Markham PD, Ablashi DV, Salahuddin SZ, Tschachler E, Wong-Staal F, Gallo RC. Productive dual infection of human CD4+ T lymphocytes by HIV-1 and HHV-6. Nature. 337: 370-3. PMID 2463490 DOI: 10.1038/337370A0  0.53
1988 Looney DJ, Fisher AG, Putney SD, Rusche JR, Redfield RR, Burke DS, Gallo RC, Wong-Staal F. Type-restricted neutralization of molecular clones of human immunodeficiency virus. Science (New York, N.Y.). 241: 357-9. PMID 3388046 DOI: 10.1126/Science.3388046  0.523
1988 Nakamura S, Salahuddin SZ, Biberfeld P, Ensoli B, Markham PD, Wong-Staal F, Gallo RC. Kaposi's sarcoma cells: Long-term culture with growth factor from retrovirus-infected CD4+ T cells Science. 242: 426-430. PMID 3262925 DOI: 10.1126/Science.3262925  0.404
1988 Sadaie MR, Rappaport J, Benter T, Josephs SF, Willis R, Wong-Staal F. Missense mutations in an infectious human immunodeficiency viral genome: Functional mapping of tat and identification of the rev splice acceptor Proceedings of the National Academy of Sciences of the United States of America. 85: 9224-9228. PMID 3194421 DOI: 10.1073/pnas.85.23.9224  0.604
1988 Fisher AG, Ensoli B, Looney D, Rose A, Gallo RC, Saag MS, Shaw GM, Hahn BH, Wong-Staal F. Biologically diverse molecular variants within a single HIV-1 isolate Nature. 334: 444-447. PMID 2841608 DOI: 10.1038/334444A0  0.55
1988 Gallo R, Wong-Staal F, Montagnier L, Haseltine WA, Yoshida M. HIV/HTLV gene nomenclature [4] Nature. 333: 504. PMID 2836736 DOI: 10.1038/333504A0  0.466
1988 Mitsuya H, Looney DJ, Kuno S, Ueno R, Wong-Staal F, Broder S. Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells. Science (New York, N.Y.). 240: 646-9. PMID 2452480  0.417
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