Year |
Citation |
Score |
2024 |
McCauley M, Huston M, Condren AR, Pereira F, Cline J, Yaple-Maresh M, Painter MM, Zimmerman GE, Robertson AW, Carney N, Goodall C, Terry V, Müller R, Sherman DH, Collins KL. Structure-Activity Relationships of Natural and Semisynthetic Plecomacrolides Suggest Distinct Pathways for HIV-1 Immune Evasion and Vacuolar ATPase-Dependent Lysosomal Acidification. Journal of Medicinal Chemistry. PMID 38452116 DOI: 10.1021/acs.jmedchem.3c01574 |
0.782 |
|
2023 |
Yancey CE, Yu F, Tripathi A, Sherman DH, Dick GJ. Expression of Biosynthetic Gene Clusters in Natural Populations Suggests Temporally Dynamic Synthesis of Novel and Known Secondary Metabolites in Western Lake Erie. Applied and Environmental Microbiology. e0209222. PMID 37070981 DOI: 10.1128/aem.02092-22 |
0.681 |
|
2022 |
Kelly SP, Shende VV, Flynn AR, Dan Q, Ye Y, Smith JL, Tsukamoto S, Sigman MS, Sherman DH. Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (-)-Eurotiumin A. Journal of the American Chemical Society. PMID 36223664 DOI: 10.1021/jacs.2c06631 |
0.325 |
|
2022 |
Yancey CE, Smith DJ, Den Uyl PA, Mohamed OG, Yu F, Ruberg SA, Chaffin JD, Goodwin KD, Tripathi A, Sherman DH, Dick GJ. Metagenomic and Metatranscriptomic Insights into Population Diversity of Blooms: Spatial and Temporal Dynamics of Genotypes, Including a Partial Operon That Can Be Abundant and Expressed. Applied and Environmental Microbiology. e0246421. PMID 35438519 DOI: 10.1128/aem.02464-21 |
0.653 |
|
2021 |
Mohamed OG, Dorandish S, Lindow R, Steltz M, Shoukat I, Shoukat M, Chehade H, Baghdadi S, McAlister-Raeburn M, Kamal A, Abebe D, Ali K, Ivy C, Antonova M, Schultz P, ... ... Sherman D, et al. Identification of a New Antimicrobial, Desertomycin H, Utilizing a Modified Crowded Plate Technique. Marine Drugs. 19. PMID 34436264 DOI: 10.3390/md19080424 |
0.679 |
|
2021 |
Hohlman RM, Newmister SA, Sanders JN, Khatri Y, Li S, Keramati NR, Lowell AN, Houk KN, Sherman DH. Structural diversification of hapalindole and fischerindole natural products via cascade biocatalysis. Acs Catalysis. 11: 4670-4681. PMID 34354850 DOI: 10.1021/acscatal.0c05656 |
0.36 |
|
2021 |
Hohlman RM, Sherman DH. Recent advances in hapalindole-type cyanobacterial alkaloids: biosynthesis, synthesis, and biological activity. Natural Product Reports. PMID 34032254 DOI: 10.1039/d1np00007a |
0.338 |
|
2020 |
Ye Y, Du L, Zhang X, Newmister SA, McCauley M, Alegre-Requena JV, Zhang W, Mu S, Minami A, Fraley AE, Adrover-Castellano ML, Carney NA, Shende VV, Qi F, Oikawa H, ... ... Sherman DH, et al. Fungal-derived brevianamide assembly by a stereoselective semipinacolase. Nature Catalysis. 3: 497-506. PMID 32923978 DOI: 10.1038/s41929-020-0454-9 |
0.629 |
|
2020 |
Painter MM, Zimmerman GE, Merlino MS, Robertson AW, Terry VH, Ren X, McLeod MR, Gomez-Rodriguez L, Garcia KA, Leonard JA, Leopold KE, Neevel AJ, Lubow J, Olson E, Piechocka-Trocha A, ... ... Sherman DH, et al. Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32900948 DOI: 10.1073/Pnas.2008615117 |
0.648 |
|
2020 |
Gómez-Rodríguez L, Schultz PJ, Tamayo-Castillo G, Dotson GD, Sherman DH, Tripathi A. Adipostatins E-J, New Potent Antimicrobials Identified as Inhibitors of Coenzyme-A Biosynthesis. Tetrahedron Letters. 61. PMID 32863451 DOI: 10.1016/J.Tetlet.2019.151469 |
0.707 |
|
2020 |
Shende VV, Khatri Y, Newmister SA, Sanders J, Lindovska P, Yu F, Doyon T, Kim J, Houk KN, Movassaghi M, Sherman DH. Structure and Function of NzeB, a Versatile C-C and C-N Bond Forming Diketopiperazine Dimerase. Journal of the American Chemical Society. PMID 32786740 DOI: 10.1021/Jacs.0C06312 |
0.387 |
|
2020 |
Sherman DH, Koch AA, Schmidt J, Lowell A, Hansen D, Coburn K, Chemler J. Probing Selectivity and Creating Structural Diversity Through Hybrid Polyketide Synthases. Angewandte Chemie (International Ed. in English). PMID 32357274 DOI: 10.1002/Anie.202004991 |
0.411 |
|
2020 |
Khatri Y, Hohlman RM, Mendoza J, Li S, Lowell AN, Asahara H, Sherman DH. Multi-component microscale biosynthesis of unnatural cyanobacterial indole alkaloids. Acs Synthetic Biology. PMID 32302487 DOI: 10.1021/Acssynbio.0C00038 |
0.467 |
|
2020 |
Fraley AE, Tran HT, Kelly SP, Newmister SA, Tripathi A, Kato H, Tsukamoto S, Du L, Li S, Williams RM, Sherman DH. Flavin-Dependent Monooxygenases NotI and NotI' Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides. Chembiochem : a European Journal of Chemical Biology. PMID 32246875 DOI: 10.1002/Cbic.202000004 |
0.782 |
|
2020 |
Fraley AE, Sherman DH. Enzyme evolution in fungal indole alkaloid biosynthesis. The Febs Journal. PMID 32118354 DOI: 10.1111/Febs.15270 |
0.402 |
|
2020 |
Li S, Newmister SA, Lowell AN, Zi J, Chappell CR, Yu F, Hohlman RM, Orjala J, Williams RM, Sherman DH. Control of stereoselectivity in diverse hapalindole metabolites is mediated by cofactor induced combinatorial pairing of Stig cyclases. Angewandte Chemie (International Ed. in English). PMID 32052896 DOI: 10.1002/Anie.201913686 |
0.333 |
|
2020 |
Thielman JR, Sherman DH, Williams RM. Stereoselective Synthesis of Baulamycin A. The Journal of Organic Chemistry. PMID 31970985 DOI: 10.1021/Acs.Joc.9B03443 |
0.391 |
|
2020 |
Schmidt JJ, Khatri Y, Brody SI, Zhu C, Pietraszkiewicz H, Valeriote FA, Sherman DH. A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs. Acs Chemical Biology. PMID 31961651 DOI: 10.1021/Acschembio.9B00998 |
0.461 |
|
2020 |
Fraley A, Caddell Haatveit K, Ye Y, Kelly SP, Newmister SA, Yu F, Williams RM, Smith JL, Houk KN, Sherman DH. Molecular basis for spirocycle formation in the paraherquamide biosynthetic pathway. Journal of the American Chemical Society. PMID 31904957 DOI: 10.2210/Pdb6Pvi/Pdb |
0.402 |
|
2020 |
Gómez-Rodríguez L, Schultz PJ, Tamayo-Castillo G, Dotson GD, Sherman DH, Tripathi A. Adipostatins E-J, new potent antimicrobials identified as inhibitors of coenzyme-A biosynthesis Tetrahedron Letters. 61: 151469. DOI: 10.1016/j.tetlet.2019.151469 |
0.634 |
|
2020 |
Fraley AE, Tran HT, Kelly SP, Newmister SA, Tripathi A, Kato H, Tsukamoto S, Du L, Li S, Williams RM, Sherman DH. Cover Feature: Flavin‐Dependent Monooxygenases NotI and NotI′ Mediate Spiro‐Oxindole Formation in Biosynthesis of the Notoamides (ChemBioChem 17/2020) Chembiochem. 21: 2382-2382. DOI: 10.1002/Cbic.202000548 |
0.738 |
|
2019 |
Skiba MA, Tran CL, Dan Q, Sikkema AP, Klaver Z, Gerwick WH, Sherman DH, Smith JL. Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis. Structure (London, England : 1993). PMID 31785925 DOI: 10.1016/J.Str.2019.11.004 |
0.433 |
|
2019 |
Dan Q, Newmister SA, Klas KR, Fraley AE, McAfoos TJ, Somoza AD, Sunderhaus JD, Ye Y, Shende VV, Yu F, Sanders JN, Brown WC, Zhao L, Paton RS, Houk KN, ... ... Sherman DH, et al. Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase. Nature Chemistry. PMID 31548667 DOI: 10.1038/S41557-019-0326-6 |
0.434 |
|
2019 |
Li T, Tripathi A, Yu F, Sherman DH, Rao A. DDAP: docking domain affinity and biosynthetic pathway prediction tool for type I polyketide synthases. Bioinformatics (Oxford, England). PMID 31504190 DOI: 10.1093/Bioinformatics/Btz677 |
0.665 |
|
2019 |
DeMars MD, Samora NL, Yang S, Garcia-Borràs M, Sanders JN, Houk KN, Podust LM, Sherman DH. Exploring the molecular basis for substrate specificity in homologous macrolide biosynthetic cytochromes P450. The Journal of Biological Chemistry. PMID 31488542 DOI: 10.1074/Jbc.Ra119.010352 |
0.392 |
|
2019 |
Knoot CJ, Khatri Y, Hohlman RM, Sherman DH, Pakrasi HB. Engineered production of hapalindole alkaloids in the cyanobacterium Synechococcus sp. UTEX 2973. Acs Synthetic Biology. PMID 31284716 DOI: 10.1021/Acssynbio.9B00229 |
0.442 |
|
2019 |
Kalkreuter E, CroweTipton JM, Lowell AN, Sherman DH, Williams GJ. Engineering the Substrate Specificity of a Modular Polyketide Synthase for Installation of Consecutive Non-Natural Extender Units. Journal of the American Chemical Society. PMID 30676722 DOI: 10.1021/Jacs.8B10521 |
0.35 |
|
2019 |
Dan Q, Newmister SA, Klas KR, Fraley AE, Paton RS, Houk KN, Williams RM, Sherman DH, Smith JL. Evolution of a bifunctional reductase/Diels–Alderase for fungal indole alkaloid biosynthesis Acta Crystallographica Section a Foundations and Advances. 75: a244-a245. DOI: 10.1107/S0108767319097599 |
0.38 |
|
2018 |
Kai A, Kato H, Sherman DH, Williams RM, Tsukamoto S. Isolation of a new indoxyl alkaloid, Amoenamide B, from NRRL 35600: biosynthetic implications and correction of the structure of Speramide B. Tetrahedron Letters. 50: 4236-4240. PMID 30765898 DOI: 10.1016/J.Tetlet.2018.10.034 |
0.317 |
|
2018 |
Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Structural Basis of Polyketide Synthase O-Methylation. Acs Chemical Biology. PMID 30489068 DOI: 10.1021/Acschembio.8B00687 |
0.533 |
|
2018 |
Hagan AK, Plotnick YM, Dingle RE, Mendel ZI, Cendrowski SR, Sherman DH, Tripathi A, Hanna PC. Petrobactin Protects against Oxidative Stress and Enhances Sporulation Efficiency in Bacillus anthracis Sterne. Mbio. 9. PMID 30401780 DOI: 10.1128/Mbio.02079-18 |
0.662 |
|
2018 |
Newmister SA, Romminger S, Schmidt JJ, Williams RM, Smith JL, Berlinck RGS, Sherman DH. Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Organic & Biomolecular Chemistry. PMID 30141817 DOI: 10.1039/C8Ob01565A |
0.39 |
|
2018 |
Slocum ST, Lowell AN, Tripathi AN, Shende VV, Smith JL, Sherman DH. Chemoenzymatic Dissection of Polyketide β-Branching in the Bryostatin Pathway. Methods in Enzymology. 604: 207-236. PMID 29779653 DOI: 10.1016/Bs.Mie.2018.01.034 |
0.404 |
|
2018 |
Sherman DH, Tripathi A, Park SR, Sikkema A, Cho HJ, Wu J, Lee B, Xi C, Smith JL. A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity by the Cahuitamycin Starter Unit Activating Enzyme CahJ. Chembiochem : a European Journal of Chemical Biology. PMID 29742306 DOI: 10.1002/Cbic.201800233 |
0.731 |
|
2018 |
Fraley AE, Sherman DH. Halogenase engineering and its utility in medicinal chemistry. Bioorganic & Medicinal Chemistry Letters. PMID 29731363 DOI: 10.1016/J.Bmcl.2018.04.066 |
0.349 |
|
2018 |
Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. Acs Chemical Biology. PMID 29701944 DOI: 10.1021/Acschembio.8B00252 |
0.404 |
|
2018 |
Klas KR, Kato H, Frisvad JC, Yu F, Newmister SA, Fraley AE, Sherman DH, Tsukamoto S, Williams RM. Structural and stereochemical diversity in prenylated indole alkaloids containing the bicyclo[2.2.2]diazaoctane ring system from marine and terrestrial fungi. Natural Product Reports. PMID 29632911 DOI: 10.1039/C7Np00042A |
0.405 |
|
2018 |
Newmister SA, Li S, Garcia-Borràs M, Sanders JN, Yang S, Lowell AN, Yu F, Smith JL, Williams RM, Houk KN, Sherman DH. Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis. Nature Chemical Biology. PMID 29531360 DOI: 10.1038/S41589-018-0003-X |
0.414 |
|
2018 |
Tripathi A, Park SR, Sikkema AP, Cho HJ, Wu J, Lee B, Xi C, Smith JL, Sherman DH. Cover Feature: A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ (ChemBioChem 15/2018) Chembiochem. 19: 1571-1571. DOI: 10.1002/Cbic.201800363 |
0.687 |
|
2017 |
Sugimoto K, Sadahiro Y, Kagiyama I, Kato H, Sherman DH, Williams RM, Tsukamoto S. Isolation of amoenamide A and five antipodal prenylated alkaloids fromNRRL 35600. Tetrahedron Letters. 58: 2797-2800. PMID 29622844 DOI: 10.1016/J.Tetlet.2017.05.057 |
0.308 |
|
2017 |
Gilbert MM, DeMars MD, Yang S, Grandner JM, Wang S, Wang H, Narayan ARH, Sherman DH, Houk KN, Montgomery J. Synthesis of Diverse 11- and 12-Membered Macrolactones from a Common Linear Substrate Using a Single Biocatalyst. Acs Central Science. 3: 1304-1310. PMID 29296671 DOI: 10.1021/Acscentsci.7B00450 |
0.341 |
|
2017 |
Mike LA, Tripathi A, Blankenship CM, Saluk A, Schultz PJ, Tamayo-Castillo G, Sherman DH, Mobley HLT. Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments. Chemical Communications (Cambridge, England). PMID 29139494 DOI: 10.1039/C7Cc07732G |
0.69 |
|
2017 |
Skiba MA, Sikkema AP, Moss NA, Tran CL, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit. Acs Chemical Biology. PMID 29096064 DOI: 10.1021/Acschembio.7B00746 |
0.373 |
|
2017 |
Hagan AK, Tripathi A, Berger D, Sherman DH, Hanna PC. Erratum for Hagan et al., "Petrobactin Is Exported from Bacillus anthracis by the RND-Type Exporter ApeX". Mbio. 8. PMID 29042503 DOI: 10.1128/Mbio.01686-17 |
0.619 |
|
2017 |
Almutairi MM, Svetlov MS, Hansen DA, Khabibullina NF, Klepacki D, Kang HY, Sherman DH, Vázquez-Laslop N, Polikanov YS, Mankin AS. Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. Nucleic Acids Research. 45: 9573-9582. PMID 28934499 DOI: 10.1093/Nar/Gkx673 |
0.382 |
|
2017 |
Hagan AK, Tripathi A, Berger D, Sherman DH, Hanna PC. Petrobactin Is Exported from Bacillus anthracis by the RND-Type Exporter ApeX. Mbio. 8. PMID 28900020 DOI: 10.1128/Mbio.01238-17 |
0.678 |
|
2017 |
Hansen DA, Koch AA, Sherman DH. Identification of a thioesterase bottleneck in the pikromycin pathway through full-module processing of unnatural pentaketides. Journal of the American Chemical Society. PMID 28836772 DOI: 10.1021/Jacs.7B06432 |
0.427 |
|
2017 |
Koch AA, Hansen DA, Shende VV, Furan LR, Houk KN, Jiménez-Osés G, Sherman DH. A single active site mutation in the pikromycin thioesterase generates a more effective macrocyclization catalyst. Journal of the American Chemical Society. PMID 28836768 DOI: 10.1021/Jacs.7B06436 |
0.373 |
|
2017 |
Fraley AE, Garcia-Borràs M, Tripathi A, Khare D, Mercado-Marin EV, Tran H, Dan Q, Webb G, Watts K, Crews P, Sarpong R, Williams RM, Smith JL, Houk KN, Sherman DH. Function and structure of MalA/MalA', iterative halogenases for late-stage C-H functionalization of indole alkaloids. Journal of the American Chemical Society. PMID 28777910 DOI: 10.1021/Jacs.7B06773 |
0.816 |
|
2017 |
Paul S, Ludeña Y, Villena GK, Yu F, Sherman DH, Gutiérrez-Correa M. High-quality draft genome sequence of a biofilm forming lignocellulolytic Aspergillus niger strain ATCC 10864. Standards in Genomic Sciences. 12: 37. PMID 28725336 DOI: 10.1186/S40793-017-0254-2 |
0.341 |
|
2017 |
Tay JH, Argüelles AJ, DeMars MD, Zimmerman PM, Sherman DH, Nagorny P. Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis. Journal of the American Chemical Society. PMID 28627172 DOI: 10.1021/Jacs.7B03198 |
0.303 |
|
2017 |
Lowell AN, DeMars MD, Slocum ST, Yu F, Anand K, Chemler JA, Korakavi N, Priessnitz JK, Park SR, Koch AA, Schultz PJ, Sherman DH. Chemoenzymatic total synthesis and structural diversification of tylactone-based macrolide antibiotics through late-stage polyketide assembly, tailoring, and C-H functionalization. Journal of the American Chemical Society. PMID 28525276 DOI: 10.1021/Jacs.7B02875 |
0.4 |
|
2017 |
Tietz DR, Podust LM, Sherman DH, Pochapsky TC. Solution conformations and dynamics of substrate-bound cytochrome P450 MycG. Biochemistry. PMID 28488849 DOI: 10.1021/Acs.Biochem.7B00291 |
0.304 |
|
2017 |
Kinnel RB, Esquenazi E, Leao T, Moss N, Mevers E, Pereira AR, Monroe EA, Korobeynikov A, Murray TF, Sherman D, Gerwick L, Dorrestein PC, Gerwick WH. A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens. Journal of Natural Products. PMID 28448144 DOI: 10.1021/Acs.Jnatprod.7B00019 |
0.404 |
|
2017 |
Li Z, Du L, Zhang W, Zhang X, Jiang Y, Liu K, Men P, Xu H, Fortman JL, Sherman DH, Yu B, Gao S, Li S. Complete Elucidation of the Late Steps of Bafilomycin Biosynthesis in Streptomyces lohii. The Journal of Biological Chemistry. PMID 28292933 DOI: 10.1074/Jbc.M116.751255 |
0.833 |
|
2017 |
Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH. Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids. Nature Chemical Biology. PMID 28288107 DOI: 10.1038/Nchembio.2327 |
0.363 |
|
2017 |
Koryakina I, Kasey C, McArthur JB, Lowell AN, Chemler JA, Li S, Hansen DA, Sherman DH, Williams GJ. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. Acs Chemical Biology. 12: 114-123. PMID 28103677 DOI: 10.1021/Acschembio.6B00732 |
0.397 |
|
2017 |
Mike L, Tripathi A, Sherman D, Mobley H. PD12-01 A NOVEL FAMILY OF NATURAL PRODUCTS THAT TARGETS UROPATHOGENIC
ESCHERISCHIA COLI
IRON ACQUISITION Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.676 |
0.657 |
|
2016 |
Zhang X, Li Z, Du L, Chlipala GE, Lopez PC, Zhang W, Sherman DH, Li S. Identification of an unexpected shunt pathway product provides new insights into tirandamycin biosynthesis. Tetrahedron Letters. 57: 5919-5923. PMID 28989201 DOI: 10.1016/J.Tetlet.2016.11.080 |
0.66 |
|
2016 |
Fiers WD, Dodge GJ, Sherman DH, Smith JL, Aldrich CC. Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis. Journal of the American Chemical Society. 138: 16024-16036. PMID 27960309 DOI: 10.1021/Jacs.6B09748 |
0.611 |
|
2016 |
Chatterjee P, Davis E, Yu F, James S, Wildschutte JH, Wiegmann DD, Sherman DH, McKay RM, LiPuma JJ, Wildschutte H. Environmental pseudomonads inhibit cystic fibrosis patient-derived Pseudomonas aeruginosa. Applied and Environmental Microbiology. PMID 27881418 DOI: 10.1128/Aem.02701-16 |
0.313 |
|
2016 |
Skiba MA, Sikkema AP, Fiers WD, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase. Acs Chemical Biology. PMID 27723289 DOI: 10.1021/Acschembio.6B00759 |
0.575 |
|
2016 |
Maloney FP, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate. Proceedings of the National Academy of Sciences of the United States of America. PMID 27573844 DOI: 10.1073/Pnas.1607210113 |
0.397 |
|
2016 |
Newmister SA, Gober CM, Romminger S, Yu F, Tripathi A, Parra LL, Williams RM, Berlinck RG, Joullié MM, Sherman DH. OxaD, a versatile indolic nitrone synthase from the marine-derived fungus Penicillium oxalicum F30. Journal of the American Chemical Society. PMID 27505044 DOI: 10.1021/Jacs.6B04915 |
0.713 |
|
2016 |
DeMars MD, Sheng F, Park SR, Lowell AN, Podust LM, Sherman DH. Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway. Acs Chemical Biology. PMID 27420774 DOI: 10.1021/Acschembio.6B00479 |
0.416 |
|
2016 |
Tripathi A, Choi SS, Sherman DH, Kim ES. Thioesterase domain swapping of a linear polyketide tautomycetin with a macrocyclic polyketide pikromycin in Streptomyces sp. CK4412. Journal of Industrial Microbiology & Biotechnology. PMID 27277081 DOI: 10.1007/S10295-016-1790-2 |
0.714 |
|
2016 |
Park SR, Tripathi A, Wu J, Schultz PJ, Yim I, McQuade TJ, Yu F, Arevang CJ, Mensah AY, Tamayo-Castillo G, Xi C, Sherman DH. Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway. Nature Communications. 7: 10710. PMID 26880271 DOI: 10.1038/Ncomms10710 |
0.706 |
|
2016 |
Bertin MJ, Vulpanovici A, Monroe EA, Korobeynikov A, Sherman DH, Gerwick L, Gerwick WH. The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide. Chembiochem : a European Journal of Chemical Biology. 17: 164-73. PMID 26769357 DOI: 10.1002/Cbic.201500467 |
0.389 |
|
2016 |
Kleigrewe K, Gerwick L, Sherman DH, Gerwick WH. Unique marine derived cyanobacterial biosynthetic genes for chemical diversity. Natural Product Reports. PMID 26758451 DOI: 10.1039/C5Np00097A |
0.449 |
|
2015 |
Kagiyama I, Kato H, Nehira T, Frisvad JC, Sherman DH, Williams RM, Tsukamoto S. Taichunamides: Prenylated Indole Alkaloids from Aspergillus taichungensis (IBT 19404). Angewandte Chemie (International Ed. in English). PMID 26644336 DOI: 10.1002/Anie.201509462 |
0.352 |
|
2015 |
Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH. Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade. Journal of the American Chemical Society. PMID 26629885 DOI: 10.1021/Jacs.5B10136 |
0.374 |
|
2015 |
Sidhu A, Miller JR, Tripathi A, Garshott DM, Brownell AL, Chiego DJ, Arevang C, Zeng Q, Jackson LC, Bechler SA, Callaghan MU, Yoo GH, Sethi S, Lin HS, Callaghan JH, ... ... Sherman DH, et al. Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis. Acs Medicinal Chemistry Letters. 6: 1122-1127. PMID 26617965 DOI: 10.1021/Acsmedchemlett.5B00133 |
0.653 |
|
2015 |
Khare D, Hale WA, Tripathi A, Gu L, Sherman DH, Gerwick WH, Håkansson K, Smith JL. Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. Structure (London, England : 1993). PMID 26526850 DOI: 10.1016/J.Str.2015.09.013 |
0.814 |
|
2015 |
Klas K, Tsukamoto S, Sherman DH, Williams RM. Natural Diels-Alderases: Elusive and Irresistable. The Journal of Organic Chemistry. PMID 26495876 DOI: 10.1021/Acs.Joc.5B01951 |
0.343 |
|
2015 |
Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, ... Sherman DH, et al. Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts. Journal of Natural Products. PMID 26465675 DOI: 10.1021/Acs.Jnatprod.5B00489 |
0.352 |
|
2015 |
Almutairi MM, Park SR, Rose S, Hansen DA, Vázquez-Laslop N, Douthwaite S, Sherman DH, Mankin AS. Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438831 DOI: 10.1073/Pnas.1512090112 |
0.32 |
|
2015 |
Cruz PG, Fribley AM, Miller JR, Larsen MJ, Schultz PJ, Jacob RT, Tamayo-Castillo G, Kaufman RJ, Sherman DH. Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts. Acs Medicinal Chemistry Letters. 6: 877-81. PMID 26288688 DOI: 10.1021/Acsmedchemlett.5B00127 |
0.311 |
|
2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Sherman DH, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.45 |
|
2015 |
Chemler JA, Tripathi A, Hansen DA, O'Neil-Johnson M, Williams RB, Starks C, Park SR, Sherman DH. Evolution of Efficient Modular Polyketide Synthases by Homeologous Recombination. Journal of the American Chemical Society. PMID 26230368 DOI: 10.1021/Jacs.5B04842 |
0.746 |
|
2015 |
Boudreau PD, Monroe EA, Mehrotra S, Desfor S, Korobeynikov A, Sherman DH, Murray TF, Gerwick L, Dorrestein PC, Gerwick WH. Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows. Plos One. 10: e0133297. PMID 26222584 DOI: 10.1371/Journal.Pone.0133297 |
0.397 |
|
2015 |
Narayan AR, Jiménez-Osés G, Liu P, Negretti S, Zhao W, Gilbert MM, Ramabhadran RO, Yang YF, Furan LR, Li Z, Podust LM, Montgomery J, Houk KN, Sherman DH. Enzymatic hydroxylation of an unactivated methylene C-H bond guided by molecular dynamics simulations. Nature Chemistry. 7: 653-60. PMID 26201742 DOI: 10.1038/Nchem.2285 |
0.788 |
|
2015 |
Sherman DH, Tsukamoto S, Williams RM. ORGANIC SYNTHESIS. Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence". Science (New York, N.Y.). 349: 149. PMID 26160938 DOI: 10.1126/Science.Aaa9349 |
0.319 |
|
2015 |
Kleigrewe K, Almaliti J, Tian IY, Kinnel RB, Korobeynikov A, Monroe EA, Duggan BM, Di Marzo V, Sherman DH, Dorrestein PC, Gerwick L, Gerwick WH. Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. Journal of Natural Products. PMID 26149623 DOI: 10.1021/Acs.Jnatprod.5B00301 |
0.369 |
|
2015 |
Lowell AN, Santoro N, Swaney SM, McQuade TJ, Schultz PJ, Larsen MJ, Sherman DH. Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries. Chemical Biology & Drug Design. PMID 26147927 DOI: 10.1111/Cbdd.12614 |
0.332 |
|
2015 |
Schofield MM, Jain S, Porat D, Dick GJ, Sherman DH. Identification and analysis of the bacterial endosymbiont specialized for production of the chemotherapeutic natural product ET-743. Environmental Microbiology. PMID 26013440 DOI: 10.1111/1462-2920.12908 |
0.352 |
|
2015 |
Smith JL, Skiniotis G, Sherman DH. Architecture of the polyketide synthase module: surprises from electron cryo-microscopy. Current Opinion in Structural Biology. 31: 9-19. PMID 25791608 DOI: 10.1016/J.Sbi.2015.02.014 |
0.366 |
|
2015 |
Kato H, Nakahara T, Yamaguchi M, Kagiyama I, Finefield JM, Sunderhaus JD, Sherman DH, Williams RM, Tsukamoto S. Bioconversion of 6-epi-Notoamide T Produces Metabolites of Unprecedented Structures in a Marine-derived Aspergillus sp. Tetrahedron Letters. 56: 247-251. PMID 25767298 DOI: 10.1016/J.Tetlet.2014.11.083 |
0.339 |
|
2015 |
Hansen DA, Koch AA, Sherman DH. Substrate controlled divergence in polyketide synthase catalysis. Journal of the American Chemical Society. 137: 3735-8. PMID 25730816 DOI: 10.1021/Ja511743N |
0.406 |
|
2015 |
Bernard SM, Akey DL, Tripathi A, Park SR, Konwerski JR, Anzai Y, Li S, Kato F, Sherman DH, Smith JL. Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases. Acs Chemical Biology. 10: 1340-51. PMID 25692963 DOI: 10.1021/Cb5009348 |
0.792 |
|
2015 |
Delekta PC, Raveh A, Larsen MJ, Schultz PJ, Tamayo-Castillo G, Sherman DH, Miller DJ. The combined use of alphavirus replicons and pseudoinfectious particles for the discovery of antivirals derived from natural products. Journal of Biomolecular Screening. 20: 673-80. PMID 25550354 DOI: 10.1177/1087057114564868 |
0.306 |
|
2015 |
Shinde PB, Oh HS, Choi H, Rathwell K, Ban YH, Kim EJ, Yang I, Lee DG, Sherman DH, Kang HY, Yoon YJ. Chemoenzymatic Synthesis of Glycosylated Macrolactam Analogues of the Macrolide Antibiotic YC-17 Advanced Synthesis and Catalysis. 357: 2697-2711. DOI: 10.1002/Adsc.201500250 |
0.321 |
|
2014 |
Vargas-Asensio G, Pinto-Tomas A, Rivera B, Hernandez M, Hernandez C, Soto-Montero S, Murillo C, Sherman DH, Tamayo-Castillo G. Uncovering the cultivable microbial diversity of costa rican beetles and its ability to break down plant cell wall components. Plos One. 9: e113303. PMID 25411842 DOI: 10.1371/Journal.Pone.0113303 |
0.331 |
|
2014 |
Raveh A, Schultz PJ, Aschermann L, Carpenter C, Tamayo-Castillo G, Cao S, Clardy J, Neubig RR, Sherman DH, Sjögren B. Identification of protein kinase C activation as a novel mechanism for RGS2 protein upregulation through phenotypic screening of natural product extracts. Molecular Pharmacology. 86: 406-16. PMID 25086086 DOI: 10.1124/Mol.114.092403 |
0.321 |
|
2014 |
Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G. Structural rearrangements of a polyketide synthase module during its catalytic cycle. Nature. 510: 560-4. PMID 24965656 DOI: 10.1038/Nature13409 |
0.817 |
|
2014 |
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G. Structure of a modular polyketide synthase. Nature. 510: 512-7. PMID 24965652 DOI: 10.1038/Nature13423 |
0.816 |
|
2014 |
Newmister SA, Sherman DH. Crystal structures of acyl carrier protein in complex with two catalytic partners show a dynamic role in cellular metabolism. Chembiochem : a European Journal of Chemical Biology. 15: 1079-81. PMID 24771327 DOI: 10.1002/Cbic.201402095 |
0.317 |
|
2014 |
Walter GM, Raveh A, Mok SA, McQuade TJ, Arevang CJ, Schultz PJ, Smith MC, Asare S, Cruz PG, Wisen S, Matainaho T, Sherman DH, Gestwicki JE. High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity. Chemical Biology & Drug Design. 83: 440-9. PMID 24636344 DOI: 10.1111/Cbdd.12259 |
0.322 |
|
2014 |
Negretti S, Narayan AR, Chiou KC, Kells PM, Stachowski JL, Hansen DA, Podust LM, Montgomery J, Sherman DH. Directing group-controlled regioselectivity in an enzymatic C-H bond oxygenation. Journal of the American Chemical Society. 136: 4901-4. PMID 24627965 DOI: 10.1021/Ja5016052 |
0.787 |
|
2014 |
Zhang W, Liu Y, Yan J, Cao S, Bai F, Yang Y, Huang S, Yao L, Anzai Y, Kato F, Podust LM, Sherman DH, Li S. New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners. Journal of the American Chemical Society. 136: 3640-6. PMID 24521145 DOI: 10.1021/Ja4130302 |
0.641 |
|
2014 |
Coates RC, Podell S, Korobeynikov A, Lapidus A, Pevzner P, Sherman DH, Allen EE, Gerwick L, Gerwick WH. Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways. Plos One. 9: e85140. PMID 24475038 DOI: 10.1371/Journal.Pone.0085140 |
0.354 |
|
2014 |
Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH. Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis. Journal of the American Chemical Society. 136: 1579-86. PMID 24401083 DOI: 10.1021/Ja4115924 |
0.8 |
|
2014 |
Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH. Correction to “Baulamycins A and B, Broad-Spectrum Antibiotics Identified as Inhibitors of Siderophore Biosynthesis in Staphylococcus aureus and Bacillus anthracis” Journal of the American Chemical Society. 136: 10541-10541. DOI: 10.1021/Ja505297X |
0.773 |
|
2014 |
Li S, Zhang W, Liu Y, Anzai Y, Kato F, Podust L, Sherman D. Uncovering the broader roles of redox partner proteins for cytochrome P450 enzymes New Biotechnology. 31: S75-S76. DOI: 10.1016/J.Nbt.2014.05.1785 |
0.592 |
|
2013 |
Raveh A, Delekta PC, Dobry CJ, Peng W, Schultz PJ, Blakely PK, Tai AW, Matainaho T, Irani DN, Sherman DH, Miller DJ. Discovery of potent broad spectrum antivirals derived from marine actinobacteria. Plos One. 8: e82318. PMID 24349254 DOI: 10.1371/Journal.Pone.0082318 |
0.384 |
|
2013 |
Whicher JR, Smaga SS, Hansen DA, Brown WC, Gerwick WH, Sherman DH, Smith JL. Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis. Chemistry & Biology. 20: 1340-51. PMID 24183970 DOI: 10.1016/J.Chembiol.2013.09.015 |
0.349 |
|
2013 |
Hansen DA, Rath CM, Eisman EB, Narayan AR, Kittendorf JD, Mortison JD, Yoon YJ, Sherman DH. Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. Journal of the American Chemical Society. 135: 11232-8. PMID 23866020 DOI: 10.1021/Ja404134F |
0.792 |
|
2013 |
Schofield MM, Sherman DH. Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis. Current Opinion in Biotechnology. 24: 1151-8. PMID 23731715 DOI: 10.1016/J.Copbio.2013.05.001 |
0.4 |
|
2013 |
Zhang W, Fortman JL, Carlson JC, Yan J, Liu Y, Bai F, Guan W, Jia J, Matainaho T, Sherman DH, Li S. Characterization of the bafilomycin biosynthetic gene cluster from Streptomyces lohii. Chembiochem : a European Journal of Chemical Biology. 14: 301-6. PMID 23362147 DOI: 10.1002/Cbic.201200743 |
0.795 |
|
2013 |
Narayan AR, Sherman DH. Chemistry. Re-engineering nature's catalysts. Science (New York, N.Y.). 339: 283-4. PMID 23329039 DOI: 10.1126/Science.1233324 |
0.794 |
|
2013 |
Sunderhaus JD, McAfoos TJ, Finefield JM, Kato H, Li S, Tsukamoto S, Sherman DH, Williams RM. Synthesis and bioconversions of notoamide T: a biosynthetic precursor to stephacidin A and notoamide B. Organic Letters. 15: 22-5. PMID 23249380 DOI: 10.1021/Ol302901P |
0.578 |
|
2013 |
Sherman D, Skiniotis G, Smith J, Håkansson K, Dutta S, Whicher J, Hansen D, Hale W, Chemler J, Congdon G, Narayan A. The Structure and Rearrangements of a Complete Polyketide Synthase Module During its Catalytic Cycle Planta Medica. 79. DOI: 10.1055/S-0033-1348499 |
0.783 |
|
2012 |
Li S, Anand K, Tran H, Yu F, Finefield JM, Sunderhaus JD, McAfoos TJ, Tsukamoto S, Williams RM, Sherman DH. Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways. Medchemcomm. 3: 987-996. PMID 23213353 DOI: 10.1039/C2Md20029E |
0.667 |
|
2012 |
Kim EJ, Lee JH, Choi H, Pereira AR, Ban YH, Yoo YJ, Kim E, Park JW, Sherman DH, Gerwick WH, Yoon YJ. Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product. Organic Letters. 14: 5824-7. PMID 23148802 DOI: 10.1021/Ol302575H |
0.35 |
|
2012 |
Majmudar CY, Højfeldt JW, Arevang CJ, Pomerantz WC, Gagnon JK, Schultz PJ, Cesa LC, Doss CH, Rowe SP, Vásquez V, Tamayo-Castillo G, Cierpicki T, Brooks CL, Sherman DH, Mapp AK. Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300. Angewandte Chemie (International Ed. in English). 51: 11258-62. PMID 23042634 DOI: 10.1002/Anie.201206815 |
0.308 |
|
2012 |
McCarthy JG, Eisman EB, Kulkarni S, Gerwick L, Gerwick WH, Wipf P, Sherman DH, Smith JL. Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. Acs Chemical Biology. 7: 1994-2003. PMID 22991895 DOI: 10.1021/Cb300385M |
0.416 |
|
2012 |
Li S, Tietz DR, Rutaganira FU, Kells PM, Anzai Y, Kato F, Pochapsky TC, Sherman DH, Podust LM. Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions. The Journal of Biological Chemistry. 287: 37880-90. PMID 22952225 DOI: 10.1074/Jbc.M112.410340 |
0.652 |
|
2012 |
Podust LM, Sherman DH. Diversity of P450 enzymes in the biosynthesis of natural products. Natural Product Reports. 29: 1251-66. PMID 22820933 DOI: 10.1039/C2Np20020A |
0.41 |
|
2012 |
Shareef AR, Sherman DH, Montgomery J. Nickel-Catalyzed Regiodivergent Approach to Macrolide Motifs. Chemical Science (Royal Society of Chemistry : 2010). 3: 892-895. PMID 22737401 DOI: 10.1039/C2Sc00866A |
0.369 |
|
2012 |
Kim D, Nah JH, Choi SS, Shin HS, Sherman DH, Kim ES. Biological activities of an engineered tautomycetin analogue via disruption of tmcR-encoding hydroxylase in Streptomyces sp. CK4412. Journal of Industrial Microbiology & Biotechnology. 39: 1563-8. PMID 22733296 DOI: 10.1007/S10295-012-1157-2 |
0.406 |
|
2012 |
Bolduc KL, Larsen SD, Sherman DH. Efficient, divergent synthesis of cryptophycin unit A analogues. Chemical Communications (Cambridge, England). PMID 22617820 DOI: 10.1039/C2Cc32417B |
0.317 |
|
2012 |
Finefield JM, Sherman DH, Kreitman M, Williams RM. Enantiomeric natural products: occurrence and biogenesis. Angewandte Chemie (International Ed. in English). 51: 4802-36. PMID 22555867 DOI: 10.1002/Anie.201107204 |
0.325 |
|
2012 |
Anzai Y, Tsukada S, Sakai A, Masuda R, Harada C, Domeki A, Li S, Kinoshita K, Sherman DH, Kato F. Function of cytochrome P450 enzymes MycCI and MycG in Micromonospora griseorubida, a producer of the macrolide antibiotic mycinamicin. Antimicrobial Agents and Chemotherapy. 56: 3648-56. PMID 22547618 DOI: 10.1128/Aac.06063-11 |
0.637 |
|
2012 |
Finefield JM, Frisvad JC, Sherman DH, Williams RM. Fungal origins of the bicyclo[2.2.2]diazaoctane ring system of prenylated indole alkaloids. Journal of Natural Products. 75: 812-33. PMID 22502590 DOI: 10.1021/Np200954V |
0.398 |
|
2012 |
Chemler JA, Buchholz TJ, Geders TW, Akey DL, Rath CM, Chlipala GE, Smith JL, Sherman DH. Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor. Journal of the American Chemical Society. 134: 7359-66. PMID 22480290 DOI: 10.1021/Ja2112228 |
0.813 |
|
2012 |
Nusca TD, Kim Y, Maltseva N, Lee JY, Eschenfeldt W, Stols L, Schofield MM, Scaglione JB, Dixon SD, Oves-Costales D, Challis GL, Hanna PC, Pfleger BF, Joachimiak A, Sherman DH. Functional and structural analysis of the siderophore synthetase AsbB through reconstitution of the petrobactin biosynthetic pathway from Bacillus anthracis. The Journal of Biological Chemistry. 287: 16058-72. PMID 22408253 DOI: 10.1074/Jbc.M112.359349 |
0.832 |
|
2012 |
Lee MJ, Kong D, Han K, Sherman DH, Bai L, Deng Z, Lin S, Kim ES. Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica. Applied Microbiology and Biotechnology. 95: 157-68. PMID 22382166 DOI: 10.1007/S00253-012-3955-X |
0.44 |
|
2012 |
Li S, Finefield JM, Sunderhaus JD, McAfoos TJ, Williams RM, Sherman DH. Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloids. Journal of the American Chemical Society. 134: 788-91. PMID 22188465 DOI: 10.1021/Ja2093212 |
0.649 |
|
2012 |
Gehret JJ, Gu L, Geders TW, Brown WC, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Structure and activity of DmmA, a marine haloalkane dehalogenase. Protein Science : a Publication of the Protein Society. 21: 239-48. PMID 22124946 DOI: 10.1002/Pro.2009 |
0.575 |
|
2012 |
Busche A, Gottstein D, Hein C, Ripin N, Pader I, Tufar P, Eisman EB, Gu L, Walsh CT, Sherman DH, Löhr F, Güntert P, Dötsch V. Characterization of molecular interactions between ACP and halogenase domains in the Curacin A polyketide synthase. Acs Chemical Biology. 7: 378-86. PMID 22103656 DOI: 10.1021/Cb200352Q |
0.682 |
|
2012 |
Li S, Finefield JM, Sunderhaus JD, McAfoos TJ, Williams RM, Sherman DH. Correction to “Biochemical Characterization of NotB as an FAD-Dependent Oxidase in the Biosynthesis of Notoamide Indole Alkaloids” Journal of the American Chemical Society. 134: 20565-20565. DOI: 10.1021/Ja3107753 |
0.602 |
|
2012 |
Nah JH, Choi SS, Kim D, Shin HS, Sherman DH, Kim ES. Biosynthesis of an engineered tautomycetin analogue via disruption of tmcK-encoding terminal decarboxylase in Streptomyces CK4412 Process Biochemistry. 47: 1773-1778. DOI: 10.1016/J.Procbio.2012.05.022 |
0.427 |
|
2012 |
Buchholz TJ, Kittendorf JD, Sherman DH. Modular Polyketide Synthases Natural Products in Chemical Biology. 163-187. DOI: 10.1002/9781118391815.ch7 |
0.755 |
|
2011 |
Finefield JM, Greshock TJ, Sherman DH, Tsukamoto S, Williams RM. Notoamide E: Biosynthetic incorporation into notoamides C and D in cultures of Aspergillus versicolor NRRL 35600. Tetrahedron Letters. 52: 1987-1989. PMID 22140279 DOI: 10.1016/J.Tetlet.2011.02.078 |
0.315 |
|
2011 |
Cruz PG, Auld DS, Schultz PJ, Lovell S, Battaile KP, MacArthur R, Shen M, Tamayo-Castillo G, Inglese J, Sherman DH. Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors. Chemistry & Biology. 18: 1442-52. PMID 22118678 DOI: 10.1016/J.Chembiol.2011.08.011 |
0.327 |
|
2011 |
Bonnett SA, Rath CM, Shareef AR, Joels JR, Chemler JA, Håkansson K, Reynolds K, Sherman DH. Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS. Chemistry & Biology. 18: 1075-81. PMID 21944746 DOI: 10.1016/J.Chembiol.2011.07.016 |
0.802 |
|
2011 |
Akey DL, Li S, Konwerski JR, Confer LA, Bernard SM, Anzai Y, Kato F, Sherman DH, Smith JL. A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway. Journal of Molecular Biology. 413: 438-50. PMID 21884704 DOI: 10.1016/J.Jmb.2011.08.040 |
0.649 |
|
2011 |
Rath CM, Janto B, Earl J, Ahmed A, Hu FZ, Hiller L, Dahlgren M, Kreft R, Yu F, Wolff JJ, Kweon HK, Christiansen MA, Håkansson K, Williams RM, Ehrlich GD, ... Sherman DH, et al. Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743. Acs Chemical Biology. 6: 1244-56. PMID 21875091 DOI: 10.1021/Cb200244T |
0.818 |
|
2011 |
Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, ... ... Sherman DH, et al. Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response. Journal of Biomolecular Screening. 16: 825-35. PMID 21844328 DOI: 10.1177/1087057111414893 |
0.576 |
|
2011 |
Ding Y, Rath CM, Bolduc KL, Håkansson K, Sherman DH. Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module. Journal of the American Chemical Society. 133: 14492-5. PMID 21823639 DOI: 10.1021/Ja204716F |
0.82 |
|
2011 |
Sunderhaus JD, Sherman DH, Williams RM. Studies on the Biosynthesis of the Stephacidin and Notoamide Natural Products: A Stereochemical and Genetic Conundrum. Israel Journal of Chemistry. 51: 442-452. PMID 21818159 DOI: 10.1002/Ijch.201100016 |
0.434 |
|
2011 |
Carlson JC, Li S, Gunatilleke SS, Anzai Y, Burr DA, Podust LM, Sherman DH. Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes. Nature Chemistry. 3: 628-33. PMID 21778983 DOI: 10.1038/Nchem.1087 |
0.748 |
|
2011 |
Finefield JM, Kato H, Greshock TJ, Sherman DH, Tsukamoto S, Williams RM. Biosynthetic studies of the notoamides: isotopic synthesis of stephacidin A and incorporation into notoamide B and sclerotiamide. Organic Letters. 13: 3802-5. PMID 21714564 DOI: 10.1021/Ol201284Y |
0.327 |
|
2011 |
Singh S, Chang A, Goff RD, Bingman CA, Grüschow S, Sherman DH, Phillips GN, Thorson JS. Structural characterization of the mitomycin 7-O-methyltransferase. Proteins. 79: 2181-8. PMID 21538548 DOI: 10.1002/Prot.23040 |
0.345 |
|
2011 |
Finefield JM, Sherman DH, Tsukamoto S, Williams RM. Studies on the biosynthesis of the notoamides: synthesis of an isotopomer of 6-hydroxydeoxybrevianamide E and biosynthetic incorporation into notoamide J. The Journal of Organic Chemistry. 76: 5954-8. PMID 21504234 DOI: 10.1021/Jo200218A |
0.37 |
|
2011 |
Gu L, Eisman EB, Dutta S, Franzmann TM, Walter S, Gerwick WH, Skiniotis G, Sherman DH. Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect. Angewandte Chemie (International Ed. in English). 50: 2795-8. PMID 21387490 DOI: 10.1002/Anie.201005280 |
0.547 |
|
2011 |
Gehret JJ, Gu L, Gerwick WH, Wipf P, Sherman DH, Smith JL. Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase. The Journal of Biological Chemistry. 286: 14445-54. PMID 21357626 DOI: 10.1074/Jbc.M110.214635 |
0.621 |
|
2010 |
McAfoos TJ, Li S, Tsukamoto S, Sherman DH, Williams RM. STUDIES ON THE BIOSYNTHESIS OF THE STEPHACIDINS AND NOTOAMIDES. TOTAL SYNTHESIS OF NOTOAMIDE S. Heterocycles. 82: 461-472. PMID 21796227 DOI: 10.3987/Com-10-S(E)19 |
0.618 |
|
2010 |
Buchholz TJ, Rath CM, Lopanik NB, Gardner NP, Håkansson K, Sherman DH. Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase. Chemistry & Biology. 17: 1092-100. PMID 21035732 DOI: 10.1016/J.Chembiol.2010.08.008 |
0.813 |
|
2010 |
Himpsl SD, Pearson MM, Arewång CJ, Nusca TD, Sherman DH, Mobley HL. Proteobactin and a yersiniabactin-related siderophore mediate iron acquisition in Proteus mirabilis. Molecular Microbiology. 78: 138-57. PMID 20923418 DOI: 10.1111/J.1365-2958.2010.07317.X |
0.786 |
|
2010 |
Mortison JD, Sherman DH. Frontiers and opportunities in chemoenzymatic synthesis. The Journal of Organic Chemistry. 75: 7041-51. PMID 20882949 DOI: 10.1021/Jo101124N |
0.813 |
|
2010 |
Ding Y, de Wet JR, Cavalcoli J, Li S, Greshock TJ, Miller KA, Finefield JM, Sunderhaus JD, McAfoos TJ, Tsukamoto S, Williams RM, Sherman DH. Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp. Journal of the American Chemical Society. 132: 12733-40. PMID 20722388 DOI: 10.1021/Ja1049302 |
0.736 |
|
2010 |
Khare D, Wang B, Gu L, Razelun J, Sherman DH, Gerwick WH, HÃ¥kansson K, Smith JL. Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 14099-104. PMID 20660778 DOI: 10.1073/Pnas.1006738107 |
0.753 |
|
2010 |
Scaglione JB, Akey DL, Sullivan R, Kittendorf JD, Rath CM, Kim ES, Smith JL, Sherman DH. Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase. Angewandte Chemie (International Ed. in English). 49: 5726-30. PMID 20623733 DOI: 10.1002/Anie.201000032 |
0.736 |
|
2010 |
Carlson PE, Dixon SD, Janes BK, Carr KA, Nusca TD, Anderson EC, Keene SE, Sherman DH, Hanna PC. Genetic analysis of petrobactin transport in Bacillus anthracis. Molecular Microbiology. 75: 900-9. PMID 20487286 DOI: 10.1111/J.1365-2958.2009.07025.X |
0.78 |
|
2010 |
Jones AC, Monroe EA, Eisman EB, Gerwick L, Sherman DH, Gerwick WH. The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria. Natural Product Reports. 27: 1048-65. PMID 20442916 DOI: 10.1039/C000535E |
0.4 |
|
2010 |
Tsukada S, Anzai Y, Li S, Kinoshita K, Sherman DH, Kato F. Gene targeting for O-methyltransferase genes, mycE and mycF, on the chromosome of Micromonospora griseorubida producing mycinamicin with a disruption cassette containing the bacteriophage phi C31 attB attachment site. Fems Microbiology Letters. 304: 148-56. PMID 20158522 DOI: 10.1111/J.1574-6968.2010.01899.X |
0.622 |
|
2010 |
Akey DL, Razelun JR, Tehranisa J, Sherman DH, Gerwick WH, Smith JL. Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway. Structure (London, England : 1993). 18: 94-105. PMID 20152156 DOI: 10.1016/J.Str.2009.10.018 |
0.418 |
|
2010 |
Carlson JC, Fortman JL, Anzai Y, Li S, Burr DA, Sherman DH. Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9. Chembiochem : a European Journal of Chemical Biology. 11: 564-72. PMID 20127927 DOI: 10.1002/Cbic.200900658 |
0.811 |
|
2010 |
Ding Y, Sherman DH. The role of synthesis and biosynthetic logic Comprehensive Natural Products Ii: Chemistry and Biology. 2: 559-579. |
0.437 |
|
2010 |
Rath CM, Scaglione JB, Kittendorf JD, Sherman DH. NRPS/PKS hybrid enzymes and their natural products Comprehensive Natural Products Ii: Chemistry and Biology. 1: 453-492. |
0.728 |
|
2009 |
Carlson JC, Li S, Burr DA, Sherman DH. Isolation and characterization of tirandamycins from a marine-derived Streptomyces sp. Journal of Natural Products. 72: 2076-9. PMID 19883065 DOI: 10.1021/Np9005597 |
0.709 |
|
2009 |
Sherman DH. Biochemistry: Enzyme's black box cracked open. Nature. 461: 1068-9. PMID 19847256 DOI: 10.1038/4611068A |
0.325 |
|
2009 |
Gu L, Wang B, Kulkarni A, Gehret JJ, Lloyd KR, Gerwick L, Gerwick WH, Wipf P, HÃ¥kansson K, Smith JL, Sherman DH. Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. Journal of the American Chemical Society. 131: 16033-5. PMID 19835378 DOI: 10.1021/Ja9071578 |
0.744 |
|
2009 |
Li S, Chaulagain MR, Knauff AR, Podust LM, Montgomery J, Sherman DH. Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase. Proceedings of the National Academy of Sciences of the United States of America. 106: 18463-8. PMID 19833867 DOI: 10.1073/Pnas.0907203106 |
0.65 |
|
2009 |
Mortison JD, Kittendorf JD, Sherman DH. Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases. Journal of the American Chemical Society. 131: 15784-93. PMID 19810731 DOI: 10.1021/Ja9060596 |
0.827 |
|
2009 |
Kim BG, Lee MJ, Seo J, Hwang YB, Lee MY, Han K, Sherman DH, Kim ES. Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica. Journal of Industrial Microbiology & Biotechnology. 36: 1425-34. PMID 19697072 DOI: 10.1007/S10295-009-0629-5 |
0.388 |
|
2009 |
Li MH, Ung PM, Zajkowski J, Garneau-Tsodikova S, Sherman DH. Automated genome mining for natural products. Bmc Bioinformatics. 10: 185. PMID 19531248 DOI: 10.1186/1471-2105-10-185 |
0.38 |
|
2009 |
Gu L, Wang B, Kulkarni A, Geders TW, Grindberg RV, Gerwick L, HÃ¥kansson K, Wipf P, Smith JL, Gerwick WH, Sherman DH. Metamorphic enzyme assembly in polyketide diversification. Nature. 459: 731-5. PMID 19494914 DOI: 10.1038/Nature07870 |
0.734 |
|
2009 |
Yan J, Gupta S, Sherman DH, Reynolds KA. Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules by using a matched pair of heterologous docking domains. Chembiochem : a European Journal of Chemical Biology. 10: 1537-43. PMID 19437523 DOI: 10.1002/Cbic.200900098 |
0.372 |
|
2009 |
Hu PJ, Sherman DH. DANSing with Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 106: 7685-6. PMID 19416852 DOI: 10.1073/Pnas.0903021106 |
0.323 |
|
2009 |
Li S, Anzai Y, Kinoshita K, Kato F, Sherman DH. Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics. Chembiochem : a European Journal of Chemical Biology. 10: 1297-301. PMID 19415708 DOI: 10.1002/Cbic.200900088 |
0.6 |
|
2009 |
Park SH, Choi SS, Kim YJ, Chang YK, Sherman DH, Kim ES. Functional expression of SCO7832 stimulates tautomycetin production via pathway-specific regulatory gene overexpression in Streptomyces sp. CK4412. Journal of Industrial Microbiology & Biotechnology. 36: 993-8. PMID 19408025 DOI: 10.1007/S10295-009-0580-5 |
0.357 |
|
2009 |
Jones AC, Gu L, Sorrels CM, Sherman DH, Gerwick WH. New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria. Current Opinion in Chemical Biology. 13: 216-23. PMID 19307147 DOI: 10.1016/J.Cbpa.2009.02.019 |
0.626 |
|
2009 |
Sharp K, Arthur KE, Gu L, Ross C, Harrison G, Gunasekera SP, Meickle T, Matthew S, Luesch H, Thacker RW, Sherman DH, Paul VJ. Phylogenetic and chemical diversity of three chemotypes of bloom-forming lyngbya species (Cyanobacteria: Oscillatoriales) from reefs of southeastern Florida. Applied and Environmental Microbiology. 75: 2879-88. PMID 19270119 DOI: 10.1128/Aem.02656-08 |
0.563 |
|
2009 |
Chamberland S, Grüschow S, Sherman DH, Williams RM. Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C. Organic Letters. 11: 791-4. PMID 19161340 DOI: 10.1021/Ol802631C |
0.337 |
|
2009 |
Buchholz TJ, Geders TW, Bartley FE, Reynolds KA, Smith JL, Sherman DH. Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. Acs Chemical Biology. 4: 41-52. PMID 19146481 DOI: 10.1021/Cb8002607 |
0.777 |
|
2009 |
Li S, Ouellet H, Sherman DH, Podust LM. Analysis of transient and catalytic desosamine-binding pockets in cytochrome P-450 PikC from Streptomyces venezuelae. The Journal of Biological Chemistry. 284: 5723-30. PMID 19124459 DOI: 10.1074/Jbc.M807592200 |
0.624 |
|
2009 |
Kittendorf JD, Sherman DH. The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis. Bioorganic & Medicinal Chemistry. 17: 2137-46. PMID 19027305 DOI: 10.1016/J.Bmc.2008.10.082 |
0.44 |
|
2009 |
Gu L, Wang B, Sherman D, Håkansson K. IRMPD-based quantification of ER-catalyzed saturation and cyclopropanation reactions Nature Protocols. DOI: 10.1038/Nprot.2009.131 |
0.684 |
|
2009 |
Park SH, Choi SS, Sherman DH, Kim ES. A global positive regulator afsR2 stimulates tautomycetin production via pathway-specific regulatory gene over-expression in Streptomyces sp. CK4412 Process Biochemistry. 44: 1298-1301. DOI: 10.1016/J.Procbio.2009.08.005 |
0.34 |
|
2008 |
Lopanik NB, Shields JA, Buchholz TJ, Rath CM, Hothersall J, Haygood MG, Håkansson K, Thomas CM, Sherman DH. In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. Chemistry & Biology. 15: 1175-86. PMID 19022178 DOI: 10.1016/J.Chembiol.2008.09.013 |
0.814 |
|
2008 |
Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH. Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 17133-8. PMID 18955706 DOI: 10.1073/Pnas.0808118105 |
0.806 |
|
2008 |
Ding Y, Greshock TJ, Miller KA, Sherman DH, Williams RM. Premalbrancheamide: synthesis, isotopic labeling, biosynthetic incorporation, and detection in cultures of Malbranchea aurantiaca. Organic Letters. 10: 4863-6. PMID 18844365 DOI: 10.1021/Ol8019633 |
0.511 |
|
2008 |
Hur YA, Choi SS, Sherman DH, Kim ES. Identification of TmcN as a pathway-specific positive regulator of tautomycetin biosynthesis in Streptomyces sp. CK4412. Microbiology (Reading, England). 154: 2912-9. PMID 18832298 DOI: 10.1099/Mic.0.2008/018903-0 |
0.4 |
|
2008 |
Anzai Y, Li S, Chaulagain MR, Kinoshita K, Kato F, Montgomery J, Sherman DH. Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics. Chemistry & Biology. 15: 950-9. PMID 18804032 DOI: 10.1016/J.Chembiol.2008.07.014 |
0.66 |
|
2008 |
Smith JL, Sherman DH. Biochemistry. An enzyme assembly line. Science (New York, N.Y.). 321: 1304-5. PMID 18772425 DOI: 10.1126/Science.1163785 |
0.315 |
|
2008 |
Ding Y, Gruschow S, Greshock TJ, Finefield JM, Sherman DH, Williams RM. Detection of VM55599 and preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: biosynthetic implications. Journal of Natural Products. 71: 1574-8. PMID 18754595 DOI: 10.1021/Np800292N |
0.495 |
|
2008 |
Jayapal KP, Philp RJ, Kok YJ, Yap MG, Sherman DH, Griffin TJ, Hu WS. Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor. Plos One. 3: e2097. PMID 18461186 DOI: 10.1371/Journal.Pone.0002097 |
0.332 |
|
2008 |
Ding Y, Williams RM, Sherman DH. Molecular analysis of a 4-dimethylallyltryptophan synthase from Malbranchea aurantiaca. The Journal of Biological Chemistry. 283: 16068-76. PMID 18390548 DOI: 10.1074/Jbc.M801991200 |
0.621 |
|
2008 |
Ding Y, Seufert WH, Beck ZQ, Sherman DH. Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity. Journal of the American Chemical Society. 130: 5492-8. PMID 18366166 DOI: 10.1021/Ja710520Q |
0.587 |
|
2008 |
Miller KA, Welch TR, Greshock TJ, Ding Y, Sherman DH, Williams RM. Biomimetic total synthesis of malbrancheamide and malbrancheamide B. The Journal of Organic Chemistry. 73: 3116-9. PMID 18345688 DOI: 10.1021/Jo800116Y |
0.524 |
|
2008 |
Lian W, Jayapal KP, Charaniya S, Mehra S, Glod F, Kyung YS, Sherman DH, Hu WS. Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2). Bmc Genomics. 9: 56. PMID 18230178 DOI: 10.1186/1471-2164-9-56 |
0.789 |
|
2008 |
Miller KA, Welch TR, Greshock TJ, Ding Y, Sherman DH, Williams RM. ChemInform Abstract: Biomimetic Total Synthesis of Malbrancheamide (IVa) and Malbrancheamide B (IVb). Cheminform. 39. DOI: 10.1002/chin.200835187 |
0.418 |
|
2007 |
Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. GNAT-like strategy for polyketide chain initiation. Science (New York, N.Y.). 318: 970-4. PMID 17991863 DOI: 10.1126/Science.1148790 |
0.717 |
|
2007 |
Seufert W, Beck ZQ, Sherman DH. Enzymatic release and macrolactonization of cryptophycins from a safety-catch solid support. Angewandte Chemie (International Ed. in English). 46: 9298-300. PMID 17979172 DOI: 10.1002/Anie.200703665 |
0.375 |
|
2007 |
Geders TW, Gu L, Mowers JC, Liu H, Gerwick WH, Håkansson K, Sherman DH, Smith JL. Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching. The Journal of Biological Chemistry. 282: 35954-63. PMID 17928301 DOI: 10.1074/Jbc.M703921200 |
0.755 |
|
2007 |
Li S, Podust LM, Sherman DH. Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain. Journal of the American Chemical Society. 129: 12940-1. PMID 17915876 DOI: 10.1021/Ja075842D |
0.607 |
|
2007 |
Kittendorf JD, Beck BJ, Buchholz TJ, Seufert W, Sherman DH. Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase. Chemistry & Biology. 14: 944-54. PMID 17719493 DOI: 10.1016/J.Chembiol.2007.07.013 |
0.776 |
|
2007 |
Jayapal KP, Lian W, Glod F, Sherman DH, Hu WS. Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans. Bmc Genomics. 8: 229. PMID 17623098 DOI: 10.1186/1471-2164-8-229 |
0.544 |
|
2007 |
Beck ZQ, Burr DA, Sherman DH. Characterization of the beta-methylaspartate-alpha-decarboxylase (CrpG) from the cryptophycin biosynthetic pathway. Chembiochem : a European Journal of Chemical Biology. 8: 1373-5. PMID 17600793 DOI: 10.1002/Cbic.200700162 |
0.513 |
|
2007 |
Kwon SJ, Lee MY, Ku B, Sherman DH, Dordick JS. High-throughput, microarray-based synthesis of natural product analogues via in vitro metabolic pathway construction. Acs Chemical Biology. 2: 419-25. PMID 17530734 DOI: 10.1021/Cb700033S |
0.451 |
|
2007 |
Sitachitta N, Lopanik NB, Mao Y, Sherman DH. Analysis of a parallel branch in the mitomycin biosynthetic pathway involving the mitN-encoded aziridine N-methyltransferase. The Journal of Biological Chemistry. 282: 20941-7. PMID 17507379 DOI: 10.1074/Jbc.M702456200 |
0.582 |
|
2007 |
Grüschow S, Chang LC, Mao Y, Sherman DH. Hydroxyquinone O-methylation in mitomycin biosynthesis. Journal of the American Chemical Society. 129: 6470-6. PMID 17461583 DOI: 10.1021/Ja0700193 |
0.537 |
|
2007 |
Grüschow S, Buchholz TJ, Seufert W, Dordick JS, Sherman DH. Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor Type III polyketide synthases. Chembiochem : a European Journal of Chemical Biology. 8: 863-8. PMID 17440908 DOI: 10.1002/Cbic.200700026 |
0.793 |
|
2007 |
Passalacqua KD, Bergman NH, Lee JY, Sherman DH, Hanna PC. The global transcriptional responses of Bacillus anthracis Sterne (34F2) and a Delta sodA1 mutant to paraquat reveal metal ion homeostasis imbalances during endogenous superoxide stress. Journal of Bacteriology. 189: 3996-4013. PMID 17384197 DOI: 10.1128/Jb.00185-07 |
0.309 |
|
2007 |
Choi SS, Hur YA, Sherman DH, Kim ES. Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412. Microbiology (Reading, England). 153: 1095-102. PMID 17379718 DOI: 10.1099/Mic.0.2006/003194-0 |
0.417 |
|
2007 |
Pfleger BF, Lee JY, Somu RV, Aldrich CC, Hanna PC, Sherman DH. Characterization and analysis of early enzymes for petrobactin biosynthesis in Bacillus anthracis. Biochemistry. 46: 4147-57. PMID 17346033 DOI: 10.1021/Bi6023995 |
0.619 |
|
2007 |
Li S, Grüschow S, Dordick JS, Sherman DH. Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase. The Journal of Biological Chemistry. 282: 12765-72. PMID 17331946 DOI: 10.1074/Jbc.M700393200 |
0.658 |
|
2007 |
Liu H, Håkansson K, Lee JY, Sherman DH. Collision-activated dissociation, infrared multiphoton dissociation, and electron capture dissociation of the Bacillus anthracis siderophore petrobactin and its metal ion complexes. Journal of the American Society For Mass Spectrometry. 18: 842-9. PMID 17331739 DOI: 10.1016/J.Jasms.2007.01.005 |
0.595 |
|
2007 |
Sudek S, Lopanik NB, Waggoner LE, Hildebrand M, Anderson C, Liu H, Patel A, Sherman DH, Haygood MG. Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina. Journal of Natural Products. 70: 67-74. PMID 17253852 DOI: 10.1021/Np060361D |
0.364 |
|
2007 |
Lee JY, Janes BK, Passalacqua KD, Pfleger BF, Bergman NH, Liu H, Håkansson K, Somu RV, Aldrich CC, Cendrowski S, Hanna PC, Sherman DH. Biosynthetic analysis of the petrobactin siderophore pathway from Bacillus anthracis. Journal of Bacteriology. 189: 1698-710. PMID 17189355 DOI: 10.1128/Jb.01526-06 |
0.713 |
|
2007 |
Oh HS, Yun JS, Nah KH, Kang HY, Sherman DH. Synthesis of the tetraketide lactones from the pikromycin biosynthetic pathway European Journal of Organic Chemistry. 3369-3379. DOI: 10.1002/Ejoc.200700254 |
0.313 |
|
2006 |
Magarvey NA, Beck ZQ, Golakoti T, Ding Y, Huber U, Hemscheidt TK, Abelson D, Moore RE, Sherman DH. Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts. Acs Chemical Biology. 1: 766-79. PMID 17240975 DOI: 10.1021/Cb6004307 |
0.771 |
|
2006 |
Venkatraman L, Salomon CE, Sherman DH, Fecik RA. Total synthesis of narbonolide and biotransformation to pikromycin. The Journal of Organic Chemistry. 71: 9853-6. PMID 17168607 DOI: 10.1021/Jo062047U |
0.347 |
|
2006 |
Sherman DH, Smith JL. Clearing the skies over modular polyketide synthases. Acs Chemical Biology. 1: 505-9. PMID 17168537 DOI: 10.1021/Cb600376R |
0.401 |
|
2006 |
Kittendorf JD, Sherman DH. Developing tools for engineering hybrid polyketide synthetic pathways. Current Opinion in Biotechnology. 17: 597-605. PMID 17046237 DOI: 10.1016/J.Copbio.2006.09.005 |
0.405 |
|
2006 |
Giraldes JW, Akey DL, Kittendorf JD, Sherman DH, Smith JL, Fecik RA. Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels. Nature Chemical Biology. 2: 531-6. PMID 16969373 DOI: 10.1038/Nchembio822 |
0.442 |
|
2006 |
Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Structural basis for macrolactonization by the pikromycin thioesterase. Nature Chemical Biology. 2: 537-42. PMID 16969372 DOI: 10.1038/Nchembio824 |
0.416 |
|
2006 |
Ku B, Cha J, Srinivasan A, Kwon SJ, Jeong JC, Sherman DH, Dordick JS. Chip-based polyketide biosynthesis and functionalization. Biotechnology Progress. 22: 1102-7. PMID 16889386 DOI: 10.1021/Bp050413+ |
0.422 |
|
2006 |
Gu L, Jia J, Liu H, Håkansson K, Gerwick WH, Sherman DH. Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair. Journal of the American Chemical Society. 128: 9014-5. PMID 16834357 DOI: 10.1021/Ja0626382 |
0.754 |
|
2006 |
Sherman DH, Li S, Yermalitskaya LV, Kim Y, Smith JA, Waterman MR, Podust LM. The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae. The Journal of Biological Chemistry. 281: 26289-97. PMID 16825192 DOI: 10.1074/Jbc.M605478200 |
0.666 |
|
2006 |
Flatt PM, O'Connell SJ, McPhail KL, Zeller G, Willis CL, Sherman DH, Gerwick WH. Characterization of the initial enzymatic steps of barbamide biosynthesis. Journal of Natural Products. 69: 938-44. PMID 16792414 DOI: 10.1021/Np050523Q |
0.41 |
|
2006 |
Lee SK, Park JW, Kim JW, Jung WS, Park SR, Choi CY, Kim ES, Kim BS, Ahn JS, Sherman DH, Yoon YJ. Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae. Journal of Natural Products. 69: 847-9. PMID 16724858 DOI: 10.1021/Np060026P |
0.399 |
|
2006 |
Jung WS, Lee SK, Hong JS, Park SR, Jeong SJ, Han AR, Sohng JK, Kim BG, Choi CY, Sherman DH, Yoon YJ. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. Applied Microbiology and Biotechnology. 72: 763-9. PMID 16493552 DOI: 10.1007/S00253-006-0318-5 |
0.377 |
|
2006 |
Nishizawa T, Grüschow S, Jayamaha DH, Nishizawa-Harada C, Sherman DH. Enzymatic assembly of the bis-indole core of rebeccamycin. Journal of the American Chemical Society. 128: 724-5. PMID 16417354 DOI: 10.1021/Ja056749X |
0.383 |
|
2006 |
Mehra S, Lian W, Jayapal KP, Charaniya SP, Sherman DH, Hu WS. A framework to analyze multiple time series data: a case study with Streptomyces coelicolor. Journal of Industrial Microbiology & Biotechnology. 33: 159-72. PMID 16217633 DOI: 10.1007/S10295-005-0034-7 |
0.547 |
|
2005 |
Beck ZQ, Aldrich CC, Magarvey NA, Georg GI, Sherman DH. Chemoenzymatic synthesis of cryptophycin/arenastatin natural products. Biochemistry. 44: 13457-66. PMID 16216069 DOI: 10.1021/Bi051140U |
0.785 |
|
2005 |
Venkatraman L, Aldrich CC, Sherman DH, Fecik RA. Formal total synthesis of the polyketide macrolactone narbonolide. The Journal of Organic Chemistry. 70: 7267-72. PMID 16122247 DOI: 10.1021/Jo050924A |
0.564 |
|
2005 |
Aldrich CC, Venkatraman L, Sherman DH, Fecik RA. Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide. Journal of the American Chemical Society. 127: 8910-1. PMID 15969542 DOI: 10.1021/Ja0504340 |
0.588 |
|
2005 |
Aldrich CC, Beck BJ, Fecik RA, Sherman DH. Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates. Journal of the American Chemical Society. 127: 8441-52. PMID 15941278 DOI: 10.1021/Ja042592H |
0.573 |
|
2005 |
Fortman JL, Sherman DH. Utilizing the power of microbial genetics to bridge the gap between the promise and the application of marine natural products. Chembiochem : a European Journal of Chemical Biology. 6: 960-78. PMID 15880675 DOI: 10.1002/Cbic.200400428 |
0.789 |
|
2005 |
Nishizawa T, Aldrich CC, Sherman DH. Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243. Journal of Bacteriology. 187: 2084-92. PMID 15743957 DOI: 10.1128/Jb.187.6.2084-2092.2005 |
0.593 |
|
2005 |
Jeong JC, Srinivasan A, Grüschow S, Bach H, Sherman DH, Dordick JS. Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation. Journal of the American Chemical Society. 127: 64-5. PMID 15631450 DOI: 10.1021/Ja0441559 |
0.309 |
|
2005 |
Lee S, Basnet D, Hong J, Jung W, Choi C, Lee H, Sohng J, Ryu K, Kim D, Ahn J, Kim B, Oh H, Sherman D, Joon Yoon Y. Structural Diversification of Macrolactones by Substrate-Flexible Cytochrome P450 Monooxygenases Advanced Synthesis & Catalysis. 347: 1369-1378. DOI: 10.1002/Adsc.200404354 |
0.395 |
|
2004 |
Magarvey NA, Keller JM, Bernan V, Dworkin M, Sherman DH. Isolation and characterization of novel marine-derived actinomycete taxa rich in bioactive metabolites. Applied and Environmental Microbiology. 70: 7520-9. PMID 15574955 DOI: 10.1128/Aem.70.12.7520-7529.2004 |
0.682 |
|
2004 |
Hildebrand M, Waggoner LE, Liu H, Sudek S, Allen S, Anderson C, Sherman DH, Haygood M. bryA: an unusual modular polyketide synthase gene from the uncultivated bacterial symbiont of the marine bryozoan Bugula neritina. Chemistry & Biology. 11: 1543-52. PMID 15556005 DOI: 10.1016/J.Chembiol.2004.08.018 |
0.369 |
|
2004 |
Srinivasan A, Bach H, Sherman DH, Dordick JS. Bacterial P450-catalyzed polyketide hydroxylation on a microfluidic platform. Biotechnology and Bioengineering. 88: 528-35. PMID 15459906 DOI: 10.1002/Bit.20285 |
0.321 |
|
2004 |
Chang Z, Sitachitta N, Rossi JV, Roberts MA, Flatt PM, Jia J, Sherman DH, Gerwick WH. Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula. Journal of Natural Products. 67: 1356-67. PMID 15332855 DOI: 10.1021/Np0499261 |
0.421 |
|
2004 |
Kim BS, Sherman DH, Reynolds KA. An efficient method for creation and functional analysis of libraries of hybrid type I polyketide synthases. Protein Engineering, Design & Selection : Peds. 17: 277-84. PMID 15067106 DOI: 10.1093/Protein/Gzh032 |
0.358 |
|
2004 |
Salomon CE, Magarvey NA, Sherman DH. Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery. Natural Product Reports. 21: 105-21. PMID 15039838 DOI: 10.1039/B301384G |
0.677 |
|
2004 |
Podust LM, Bach H, Kim Y, Lamb DC, Arase M, Sherman DH, Kelly SL, Waterman MR. Comparison of the 1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2) with the closely related CYP154C1 and CYPs from antibiotic biosynthetic pathways. Protein Science : a Publication of the Protein Society. 13: 255-68. PMID 14691240 DOI: 10.1110/Ps.03384804 |
0.421 |
|
2003 |
Beck BJ, Aldrich CC, Fecik RA, Reynolds KA, Sherman DH. Substrate recognition and channeling of monomodules from the pikromycin polyketide synthase. Journal of the American Chemical Society. 125: 12551-7. PMID 14531700 DOI: 10.1021/Ja034841S |
0.584 |
|
2003 |
Beck BJ, Aldrich CC, Fecik RA, Reynolds KA, Sherman DH. Iterative chain elongation by a pikromycin monomodular polyketide synthase. Journal of the American Chemical Society. 125: 4682-3. PMID 12696866 DOI: 10.1021/Ja029974C |
0.601 |
|
2003 |
Podust LM, Kim Y, Arase M, Neely BA, Beck BJ, Bach H, Sherman DH, Lamb DC, Kelly SL, Waterman MR. The 1.92-A structure of Streptomyces coelicolor A3(2) CYP154C1. A new monooxygenase that functionalizes macrolide ring systems. The Journal of Biological Chemistry. 278: 12214-21. PMID 12519772 DOI: 10.1074/Jbc.M212210200 |
0.305 |
|
2002 |
Cropp TA, Kim BS, Beck BJ, Yoon YJ, Sherman DH, Reynolds KA. Recent developments in the production of novel polyketides by combinatorial biosynthesis. Biotechnology & Genetic Engineering Reviews. 19: 159-72. PMID 12520877 DOI: 10.1080/02648725.2002.10648028 |
0.35 |
|
2002 |
Chang Z, Flatt P, Gerwick WH, Nguyen VA, Willis CL, Sherman DH. The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit. Gene. 296: 235-47. PMID 12383521 DOI: 10.1016/S0378-1119(02)00860-0 |
0.34 |
|
2002 |
Sherman DH. New enzymes for "warheads". Nature Biotechnology. 20: 984-5. PMID 12355111 DOI: 10.1038/Nbt1002-984 |
0.414 |
|
2002 |
Kim BS, Cropp TA, Florova G, Lindsay Y, Sherman DH, Reynolds KA. An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis. Biochemistry. 41: 10827-33. PMID 12196022 DOI: 10.1021/Bi0256779 |
0.398 |
|
2002 |
Martin TW, Dauter Z, Devedjiev Y, Sheffield P, Jelen F, He M, Sherman DH, Otlewski J, Derewenda ZS, Derewenda U. Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein. Structure (London, England : 1993). 10: 933-42. PMID 12121648 DOI: 10.1016/S0969-2126(02)00778-5 |
0.465 |
|
2002 |
Beck BJ, Yoon YJ, Reynolds KA, Sherman DH. The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase. Chemistry & Biology. 9: 575-83. PMID 12031664 DOI: 10.1016/S1074-5521(02)00146-1 |
0.362 |
|
2002 |
Yoon YJ, Beck BJ, Kim BS, Kang HY, Reynolds KA, Sherman DH. Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae. Chemistry & Biology. 9: 203-14. PMID 11880035 DOI: 10.1016/S1074-5521(02)00095-9 |
0.444 |
|
2001 |
Kyung YS, Sherman DH, Hu WS. Simultaneous analysis of spatio-temporal gene expression for cephamycin biosynthesis in Streptomyces clavuligerus. Biotechnology Progress. 17: 1000-7. PMID 11735432 DOI: 10.1021/Bp0101076 |
0.722 |
|
2001 |
Zhang Q, Sherman DH. Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae. Journal of Natural Products. 64: 1447-50. PMID 11720530 DOI: 10.1021/Np010146R |
0.423 |
|
2001 |
Penketh PG, Hodnick WF, Belcourt MF, Shyam K, Sherman DH, Sartorelli AC. Inhibition of DNA cross-linking by mitomycin C by peroxidase-mediated oxidation of mitomycin C hydroquinone. The Journal of Biological Chemistry. 276: 34445-52. PMID 11457837 DOI: 10.1074/Jbc.M104263200 |
0.301 |
|
2001 |
Varoglu M, Mao Y, Sherman DH. Mapping the mitomycin biosynthetic pathway by functional analysis of the MitM aziridine N-methyltransferase. Journal of the American Chemical Society. 123: 6712-3. PMID 11439066 DOI: 10.1021/Ja015646L |
0.451 |
|
2001 |
Kyung YS, Hu WS, Sherman DH. Analysis of temporal and spatial expression of the CcaR regulatory element in the cephamycin C biosynthetic pathway using green fluorescent protein. Molecular Microbiology. 40: 530-41. PMID 11359561 DOI: 10.1046/J.1365-2958.2001.02386.X |
0.73 |
|
2001 |
Wilson DJ, Xue Y, Reynolds KA, Sherman DH. Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae. Journal of Bacteriology. 183: 3468-75. PMID 11344155 DOI: 10.1128/Jb.183.11.3468-3475.2001 |
0.571 |
|
2001 |
Chen S, Roberts JB, Xue Y, Sherman DH, Reynolds KA. The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide. Gene. 263: 255-64. PMID 11223265 DOI: 10.1016/S0378-1119(00)00560-6 |
0.567 |
|
2001 |
Xue Y, Sherman DH. Biosynthesis and combinatorial biosynthesis of pikromycin-related macrolides in Streptomyces venezuelae. Metabolic Engineering. 3: 15-26. PMID 11162229 DOI: 10.1006/Mben.2000.0167 |
0.557 |
|
2001 |
He M, Sheldon PJ, Sherman DH. Characterization of a quinone reductase activity for the mitomycin C binding protein (MRD): Functional switching from a drug-activating enzyme to a drug-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 926-31. PMID 11158572 DOI: 10.1073/Pnas.98.3.926 |
0.493 |
|
2000 |
Chen S, Xue Y, Sherman DH, Reynolds KA. Mechanisms of molecular recognition in the pikromycin polyketide synthase. Chemistry & Biology. 7: 907-18. PMID 11137814 DOI: 10.1016/S1074-5521(00)00039-9 |
0.555 |
|
2000 |
Khetan A, Hu WS, Sherman DH. Heterogeneous distribution of lysine 6-aminotransferase during cephamycin C biosynthesis in Streptomyces clavuligerus demonstrated using green fluorescent protein as a reporter. Microbiology (Reading, England). 146: 1869-80. PMID 10931891 DOI: 10.1099/00221287-146-8-1869 |
0.302 |
|
2000 |
He M, Varoglu M, Sherman DH. Structural modeling and site-directed mutagenesis of the actinorhodin beta-ketoacyl-acyl carrier protein synthase. Journal of Bacteriology. 182: 2619-23. PMID 10762267 DOI: 10.1128/Jb.182.9.2619-2623.2000 |
0.474 |
|
2000 |
Xue Y, Wilson D, Sherman DH. Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides. Gene. 245: 203-11. PMID 10713461 DOI: 10.1016/S0378-1119(00)00003-2 |
0.568 |
|
2000 |
Xue Y, Sherman DH. Alternative modular polyketide synthase expression controls macrolactone structure. Nature. 403: 571-5. PMID 10676969 DOI: 10.1038/35000624 |
0.598 |
|
1999 |
Borisova SA, Zhao L, Sherman DH, Liu HW. Biosynthesis of desosamine: construction of a new macrolide carrying a genetically designed sugar moiety. Organic Letters. 1: 133-6. PMID 10822548 DOI: 10.1021/Ol9906007 |
0.371 |
|
1999 |
Han L, Khetan A, Hu WS, Sherman DH. Time-lapsed confocal microscopy reveals temporal and spatial expression of the lysine epsilon-aminotransferase gene in Streptomyces clavuligerus. Molecular Microbiology. 34: 878-86. PMID 10594815 DOI: 10.1046/J.1365-2958.1999.01638.X |
0.336 |
|
1999 |
Khetan A, Malmberg LH, Kyung YS, Sherman DH, Hu WS. Precursor and cofactor as a check valve for cephamycin biosynthesis in Streptomyces clavuligerus. Biotechnology Progress. 15: 1020-7. PMID 10585184 DOI: 10.1021/Bp990090F |
0.739 |
|
1999 |
Belcourt MF, Penketh PG, Hodnick WF, Johnson DA, Sherman DH, Rockwell S, Sartorelli AC. Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA. Proceedings of the National Academy of Sciences of the United States of America. 96: 10489-94. PMID 10468636 DOI: 10.1073/Pnas.96.18.10489 |
0.333 |
|
1999 |
Sheldon PJ, Mao Y, He M, Sherman DH. Mitomycin resistance in Streptomyces lavendulae includes a novel drug-binding-protein-dependent export system. Journal of Bacteriology. 181: 2507-12. PMID 10198016 DOI: 10.1128/Jb.181.8.2507-2512.1999 |
0.581 |
|
1999 |
Mao Y, Varoglu M, Sherman DH. Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564. Chemistry & Biology. 6: 251-63. PMID 10099135 DOI: 10.1016/S1074-5521(99)80040-4 |
0.568 |
|
1999 |
Mao Y, Varoglu M, Sherman DH. Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C. Journal of Bacteriology. 181: 2199-208. PMID 10094699 DOI: 10.1128/Jb.181.7.2199-2208.1999 |
0.57 |
|
1999 |
Zhao L, Ahlert J, Xue Y, Thorson JS, Sherman DH, Liu HW. Engineering a methymycin/pikromycin-calicheamicin hybrid: Construction of two new macrolides carrying a designed sugar moiety [6] Journal of the American Chemical Society. 121: 9881-9882. DOI: 10.1021/Ja992810K |
0.469 |
|
1998 |
Williams MD, Rahn JA, Smith S, Joshi AK, Sherman DH. Production of a polyhydroxyalkanoate biopolymer in insect cells with a modified eucaryotic Fatty Acid synthase. Applied and Environmental Microbiology. 64: 383. PMID 16349493 DOI: 10.1128/Aem.64.1.383-383.1998 |
0.389 |
|
1998 |
Xue Y, Wilson D, Zhao L, Liu Hw, Sherman DH. Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae. Chemistry & Biology. 5: 661-7. PMID 9831532 DOI: 10.1016/S1074-5521(98)90293-9 |
0.597 |
|
1998 |
Bedekar A, Zink RM, Sherman DH, Line TV, Van Pilsum JF. The comparative amino acid sequences, substrate specificities and gene or cDNA nucleotide sequences of some prokaryote and eukaryote amidinotransferases: implications for evolution. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 119: 677-90. PMID 9787760 DOI: 10.1016/S0305-0491(98)00043-1 |
0.306 |
|
1998 |
Xue Y, Zhao L, Liu HW, Sherman DH. A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity. Proceedings of the National Academy of Sciences of the United States of America. 95: 12111-6. PMID 9770448 DOI: 10.1073/Pnas.95.21.12111 |
0.585 |
|
1998 |
Zhao L, Que NLS, Xue Y, Sherman DH, Liu H. Mechanistic Studies of Desosamine Biosynthesis: C-4 Deoxygenation Precedes C-3 Transamination Journal of the American Chemical Society. 120: 12159-12160. DOI: 10.1021/Ja982942Y |
0.47 |
|
1998 |
Zhao L, Sherman DH, Liu H. Biosynthesis of Desosamine: Construction of a New Methymycin/Neomethymycin Analogue by Deletion of a Desosamine Biosynthetic Gene Journal of the American Chemical Society. 120: 10256-10257. DOI: 10.1021/Ja981782N |
0.315 |
|
1997 |
Sheldon PJ, Johnson DA, August PR, Liu HW, Sherman DH. Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae. Journal of Bacteriology. 179: 1796-804. PMID 9045843 DOI: 10.1128/Jb.179.5.1796-1804.1997 |
0.346 |
|
1997 |
Williams MD, Fieno AM, Grant RA, Sherman DH. Expression and analysis of a bacterial poly(hydroxyalkanoate) synthase in insect cells using a baculovirus system. Protein Expression and Purification. 7: 203-11. PMID 8812862 DOI: 10.1006/Prep.1996.0028 |
0.385 |
|
1996 |
August PR, Rahn JA, Flickinger MC, Sherman DH. Inducible synthesis of the mitomycin C resistance gene product (MCRA) from Streptomyces lavendulae. Gene. 175: 261-7. PMID 8917108 DOI: 10.1016/0378-1119(96)00172-2 |
0.394 |
|
1996 |
Khetan A, Malmberg LH, Sherman DH, Hu WS. Metabolic engineering of cephalosporin biosynthesis in Streptomyces clavuligerus. Annals of the New York Academy of Sciences. 782: 17-24. PMID 8659893 DOI: 10.1111/J.1749-6632.1996.Tb40543.X |
0.398 |
|
1996 |
Malmberg LH, Hu WS, Sherman DH. Effects of enhanced lysine epsilon-aminotransferase activity on cephamycin biosynthesis in Streptomyces clavuligerus. Applied Microbiology and Biotechnology. 44: 198-205. PMID 8579831 DOI: 10.1007/Bf00164502 |
0.397 |
|
1995 |
Kim ES, Cramer KD, Shreve AL, Sherman DH. Heterologous expression of an engineered biosynthetic pathway: functional dissection of type II polyketide synthase components in Streptomyces species. Journal of Bacteriology. 177: 1202-7. PMID 7868592 DOI: 10.1128/Jb.177.5.1202-1207.1995 |
0.387 |
|
1995 |
Crosby J, Sherman DH, Bibb MJ, Revill WP, Hopwood DA, Simpson TJ. Polyketide synthase acyl carrier proteins from Streptomyces: expression in Escherichia coli, purification and partial characterisation. Biochimica Et Biophysica Acta. 1251: 32-42. PMID 7647090 DOI: 10.1016/0167-4838(95)00053-W |
0.343 |
|
1994 |
Bibb MJ, Sherman DH, Omura S, Hopwood DA. Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin. Gene. 142: 31-9. PMID 8181754 DOI: 10.1016/0378-1119(94)90351-4 |
0.36 |
|
1994 |
Kim ES, Bibb MJ, Butler MJ, Hopwood DA, Sherman DH. Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus. Gene. 141: 141-2. PMID 8163168 DOI: 10.1016/0378-1119(94)90144-9 |
0.321 |
|
1994 |
Kim ES, Hopwood DA, Sherman DH. Analysis of type II polyketide beta-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants. Journal of Bacteriology. 176: 1801-4. PMID 8132481 DOI: 10.1128/Jb.176.6.1801-1804.1994 |
0.312 |
|
1993 |
Khosla C, McDaniel R, Ebert-Khosla S, Torres R, Sherman DH, Bibb MJ, Hopwood DA. Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins. Journal of Bacteriology. 175: 2197-204. PMID 8468280 DOI: 10.1128/Jb.175.8.2197-2204.1993 |
0.438 |
|
1993 |
Malmberg LH, Hu WS, Sherman DH. Precursor flux control through targeted chromosomal insertion of the lysine epsilon-aminotransferase (lat) gene in cephamycin C biosynthesis. Journal of Bacteriology. 175: 6916-24. PMID 8226634 DOI: 10.1128/Jb.175.21.6916-6924.1993 |
0.37 |
|
1992 |
Arrowsmith TJ, Malpartida F, Sherman DH, Birch A, Hopwood DA, Robinson JA. Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis. Molecular & General Genetics : Mgg. 234: 254-64. PMID 1508151 DOI: 10.1007/Bf00283846 |
0.325 |
|
1992 |
Sherman DH, Kim ES, Bibb MJ, Hopwood DA. Functional replacement of genes for individual polyketide synthase components in Streptomyces coelicolor A3(2) by heterologous genes from a different polyketide pathway. Journal of Bacteriology. 174: 6184-90. PMID 1400167 DOI: 10.1128/Jb.174.19.6184-6190.1992 |
0.387 |
|
1991 |
Hopwood DA, Sherman DH. Molecular genetics of polyketides and its comparison to fatty acid biosynthesis. Annual Review of Genetics. 24: 37-66. PMID 2088174 DOI: 10.1146/Annurev.Ge.24.120190.000345 |
0.307 |
|
1991 |
Sherman DH, Bibb MJ, Simpson TJ, Johnson D, Malpartida F, Fernandez-Moreno M, Martinez E, Hutchinson C, Hopwood DA. Molecular genetic analysis reveals a putative bifunctional polyketide cyclase/dehydrase gene from Streptomycea coelicolor and Streptomyces violoceoruber, and a cyclase/O-methyltransferase from Streptomyces glaucescens. Tetrahedron. 47: 6029-6043. DOI: 10.1016/S0040-4020(01)86494-2 |
0.383 |
|
1989 |
Sherman DH, Malpartida F, Bibb MJ, Kieser HM, Hopwood DA. Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22. The Embo Journal. 8: 2717-2725. DOI: 10.1002/J.1460-2075.1989.Tb08413.X |
0.435 |
|
1984 |
Kranz DM, Sherman DH, Sitkovsky MV, Pasternack MS, Eisen HN. Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. Proceedings of the National Academy of Sciences of the United States of America. 81: 573-7. PMID 6607474 DOI: 10.1073/Pnas.81.2.573 |
0.527 |
|
1984 |
Sherman DH, Kranz DM, Eisen HN. Expression of structurally diverse Qa-2-encoded molecules on the surface of cloned cytotoxic T lymphocytes. The Journal of Experimental Medicine. 160: 1421-30. PMID 6333483 DOI: 10.1084/Jem.160.5.1421 |
0.551 |
|
1982 |
Stork G, Sherman DH. Efficient de novo construction of the indanpropionic acid precursor of 11-keto steroids. An improved internal Diels-Alder sequence Journal of the American Chemical Society. 104: 3758-3759. DOI: 10.1021/Ja00377A052 |
0.418 |
|
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