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Jenny P-Y Ting - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Neuroinflammation
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Year Citation  Score
2023 Wang M, Rousseau B, Qiu K, Huang G, Zhang Y, Su H, Le Bihan-Benjamin C, Khati I, Artz O, Foote MB, Cheng YY, Lee KH, Miao MZ, Sun Y, Bousquet PJ, ... ... Ting JP, et al. Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses. Nature Biotechnology. PMID 37749267 DOI: 10.1038/s41587-023-01957-8  0.568
2023 Chou WC, Jha S, Linhoff MW, Ting JP. Author Correction: The NLR gene family: from discovery to present day. Nature Reviews. Immunology. PMID 37198352 DOI: 10.1038/s41577-023-00891-9  0.738
2023 Chou WC, Jha S, Linhoff MW, Ting JP. The NLR gene family: from discovery to present day. Nature Reviews. Immunology. PMID 36973360 DOI: 10.1038/s41577-023-00849-x  0.795
2022 Barnett KC, Xie Y, Asakura T, Song D, Liang K, Taft-Benz SA, Guo H, Yang S, Okuda K, Gilmore RC, Loome JF, Oguin Iii TH, Sempowski GD, Randell SH, Heise MT, ... ... Ting JP, et al. An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2. Cell Host & Microbe. PMID 36563691 DOI: 10.1016/j.chom.2022.12.005  0.412
2022 Li S, Mirlekar B, Johnson BM, Brickey WJ, Wrobel JA, Yang N, Song D, Entwistle S, Tan X, Deng M, Cui Y, Li W, Vincent BG, Gale M, Pylayeva-Gupta Y, ... Ting JP, et al. STING-induced regulatory B cells compromise NK function in cancer immunity. Nature. PMID 36198789 DOI: 10.1038/s41586-022-05254-3  0.626
2022 Mirlekar B, Wang Y, Li S, Zhou M, Entwistle S, De Buysscher T, Morrison A, Herrera G, Harris C, Vincent BG, Ting JP, Rashid N, Kim WY, Yeh JJ, Pylayeva-Gupta Y. Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity. Cell Reports. Medicine. 3: 100744. PMID 36099917 DOI: 10.1016/j.xcrm.2022.100744  0.604
2020 Deng M, Tam JW, Wang L, Liang K, Li S, Zhang L, Guo H, Luo X, Zhang Y, Petrucelli A, Davis BK, Conti BJ, June Brickey W, Ko CC, Lei YL, ... ... Ting JP, et al. TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination. Nature Communications. 11: 2193. PMID 32366851 DOI: 10.1038/S41467-020-16014-0  0.783
2019 Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, ... ... Ting JP, et al. Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GvHD. Blood. PMID 31533918 DOI: 10.1182/Blood.2019001950  0.529
2019 Gharagozloo M, Mahmoud S, Simard C, Yamamoto K, Bobbala D, Ilangumaran S, Smith MD, Lamontagne A, Jarjoura S, Denault JB, Blais V, Gendron L, Vilariño-Güell C, Sadovnick AD, Ting JP, et al. NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity. Plos Biology. 17: e3000451. PMID 31525189 DOI: 10.1371/Journal.Pbio.3000451  0.381
2019 Chen ST, Chen L, Lin DS, Chen SY, Tsao YP, Guo H, Li FJ, Tseng WT, Tam JW, Chao CW, Brickey WJ, Dzhagalov I, Song MJ, Kang HR, Jung JU, ... Ting JP, et al. NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25. Cell Host & Microbe. PMID 30902577 DOI: 10.1016/J.Chom.2019.02.013  0.302
2019 Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP. Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon. Immunity. 50: 591-599.e6. PMID 30893587 DOI: 10.1016/J.Immuni.2019.02.009  0.327
2018 Huang JH, Liu CY, Wu SY, Chen WY, Chang TH, Kan HW, Hsieh ST, Ting JP, Wu-Hsieh BA. NLRX1 Facilitates -Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages. Frontiers in Immunology. 9: 2761. PMID 30559741 DOI: 10.3389/fimmu.2018.02761  0.306
2018 Collier MA, Junkins RD, Gallovic MD, Johnson BM, Johnson MM, Macintyre AN, Sempowski GD, Bachelder EM, Ting JP, Ainslie KM. Acetalated Dextran microparticles for co-delivery of STING and TLR7/8 agonists. Molecular Pharmaceutics. PMID 30281314 DOI: 10.1021/Acs.Molpharmaceut.8B00579  0.332
2018 Shao W, Earley LF, Chai Z, Chen X, Sun J, He T, Deng M, Hirsch ML, Ting J, Samulski RJ, Li C. Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction. Jci Insight. 3. PMID 29925692 DOI: 10.1172/jci.insight.120474  0.356
2017 Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP. A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29170142 DOI: 10.1016/J.Jconrel.2017.11.030  0.334
2017 Rotty JD, Brighton HE, Craig SL, Asokan SB, Cheng N, Ting JP, Bear JE. Arp2/3 Complex Is Required for Macrophage Integrin Functions but Is Dispensable for FcR Phagocytosis and In Vivo Motility. Developmental Cell. PMID 28867487 DOI: 10.1016/J.Devcel.2017.08.003  0.325
2017 Freeman L, Guo H, David CN, Brickey WJ, Jha S, Ting JP. NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes. The Journal of Experimental Medicine. PMID 28404595 DOI: 10.1084/Jem.20150237  0.583
2017 Bruce DW, Stefanski HE, Vincent BG, Dant TA, Reisdorf S, Bommiasamy H, Serody DA, Wilson JE, McKinnon KP, Shlomchik WD, Armistead PM, Ting JP, Woosley JT, Blazar BR, Zaiss DM, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. The Journal of Clinical Investigation. PMID 28375154 DOI: 10.1172/Jci91816  0.685
2017 Linz BM, Neely CJ, Kartchner LB, Mendoza AE, Khoury AL, Truax A, Sempowski G, Eitas T, Brickey J, Ting JP, Cairns BA, Maile R. Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis. Journal of Immunology (Baltimore, Md. : 1950). PMID 28159904 DOI: 10.4049/Jimmunol.1601048  0.303
2017 Jha S, Brickey WJ, Ting JP. Inflammasomes in Myeloid Cells: Warriors Within. Microbiology Spectrum. 5. PMID 28102121 DOI: 10.1128/Microbiolspec.Mchd-0049-2016  0.635
2016 Ley K, Pramod AB, Croft M, Ravichandran KS, Ting JP. How Mouse Macrophages Sense What Is Going On. Frontiers in Immunology. 7: 204. PMID 27313577 DOI: 10.3389/fimmu.2016.00204  0.366
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Ting JP, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.772
2015 Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, et al. GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 126: 1621-8. PMID 26265697 DOI: 10.1182/Blood-2015-03-634691  0.525
2015 Wilson JE, Petrucelli AS, Chen L, Koblansky AA, Truax AD, Oyama Y, Rogers AB, Brickey WJ, Wang Y, Schneider M, Mühlbauer M, Chou WC, Barker BR, Jobin C, Allbritton NL, ... ... Ting JP, et al. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nature Medicine. PMID 26107252 DOI: 10.1038/Nm.3908  0.789
2015 Cheong WC, Kang HR, Yoon H, Kang SJ, Ting JP, Song MJ. Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome. Plos One. 10: e0126456. PMID 25978411 DOI: 10.1371/journal.pone.0126456  0.317
2015 Kang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, Homer R, Dhamija A, Boffa D, West AP, Shadel GS, Ting JP, Tedrow JR, Kaminski N, Kim WJ, et al. Suppression of NLRX1 in chronic obstructive pulmonary disease. The Journal of Clinical Investigation. 125: 2458-62. PMID 25938787 DOI: 10.1172/Jci71747  0.37
2015 O'Brien M, Moehring D, Muñoz-Planillo R, Núñez G, Callaway J, Ting J, Scurria M, Ugo T, Bernad L, Cali J, Lazar D. Abstract 1319: Monitoring inflammasome activation with a bioluminescent caspase-1 assay Cancer Research. 75: 1319-1319. DOI: 10.1158/1538-7445.Am2015-1319  0.376
2014 Rodgers MA, Bowman JW, Fujita H, Orazio N, Shi M, Liang Q, Amatya R, Kelly TJ, Iwai K, Ting J, Jung JU. The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation. The Journal of Experimental Medicine. 211: 1333-47. PMID 24958845 DOI: 10.1084/Jem.20132486  0.391
2014 Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, ... Ting JP, et al. NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity. 40: 329-41. PMID 24560620 DOI: 10.1016/J.Immuni.2014.01.010  0.606
2013 Allen IC, McElvania-TeKippe E, Wilson JE, Lich JD, Arthur JC, Sullivan JT, Braunstein M, Ting JP. Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. Plos One. 8: e60842. PMID 23577168 DOI: 10.1371/Journal.Pone.0060842  0.644
2013 Xie L, Liu C, Wang L, Gunawardena HP, Yu Y, Du R, Taxman DJ, Dai P, Yan Z, Yu J, Holly SP, Parise LV, Wan YY, Ting JP, Chen X. Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. Cell Reports. 3: 678-88. PMID 23434512 DOI: 10.1016/J.Celrep.2013.01.029  0.407
2013 Lei Y, Wen H, Ting JP. The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy. Autophagy. 9: 432-3. PMID 23321557 DOI: 10.4161/auto.23026  0.472
2013 Roney K, Holl E, Ting J. Immune plexins and semaphorins: old proteins, new immune functions. Protein & Cell. 4: 17-26. PMID 23307780 DOI: 10.1007/S13238-012-2108-4  0.765
2012 Uittenbogaard AM, Chelvarajan RL, Myers-Morales T, Gorman AA, Brickey WJ, Ye Z, Kaplan AM, Cohen DA, Ting JP, Straley SC. Toward a molecular pathogenic pathway for Yersinia pestis YopM. Frontiers in Cellular and Infection Microbiology. 2: 155. PMID 23248776 DOI: 10.3389/Fcimb.2012.00155  0.484
2012 Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH. Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels. Plos One. 7: e51105. PMID 23226472 DOI: 10.1371/Journal.Pone.0051105  0.314
2012 Fry RC, Rager JE, Zhou H, Zou B, Brickey JW, Ting J, Lay JC, Peden DB, Alexis NE. Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways. Respiratory Research. 13: 89. PMID 23033980 DOI: 10.1186/1465-9921-13-89  0.344
2012 Holl EK, Roney KE, Allen IC, Steinbach E, Arthur JC, Buntzman A, Plevy S, Frelinger J, Ting JP. Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production. Plos One. 7: e43333. PMID 22916243 DOI: 10.1371/Journal.Pone.0043333  0.793
2012 Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nature Immunology. 13: 823-31. PMID 22863753 DOI: 10.1038/Ni.2378  0.798
2012 Taxman DJ, Swanson KV, Broglie PM, Wen H, Holley-Guthrie E, Huang MT, Callaway JB, Eitas TK, Duncan JA, Ting JP. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. The Journal of Biological Chemistry. 287: 32791-9. PMID 22843689 DOI: 10.1074/Jbc.M112.401737  0.594
2012 Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 488: 670-4. PMID 22801494 DOI: 10.1038/Nature11290  0.314
2012 Kovarova M, Hesker PR, Jania L, Nguyen M, Snouwaert JN, Xiang Z, Lommatzsch SE, Huang MT, Ting JP, Koller BH. NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 2006-16. PMID 22753929 DOI: 10.4049/Jimmunol.1201065  0.577
2012 Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, ... ... Ting JP, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity. 36: 933-46. PMID 22749352 DOI: 10.1016/J.Immuni.2012.03.025  0.489
2012 Robbins GR, Truax AD, Davis BK, Zhang L, Brickey WJ, Ting JP. Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins. The Journal of Biological Chemistry. 287: 24294-303. PMID 22645137 DOI: 10.1074/jbc.M112.364604  0.407
2012 Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity. 36: 742-54. PMID 22503542 DOI: 10.1016/J.Immuni.2012.03.012  0.719
2012 Allen IC, Jania CM, Wilson JE, Tekeppe EM, Hua X, Brickey WJ, Kwan M, Koller BH, Tilley SL, Ting JP. Analysis of NLRP3 in the development of allergic airway disease in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 2884-93. PMID 22323538 DOI: 10.4049/Jimmunol.1102488  0.323
2012 Allen IC, Lich JD, Arthur JC, Jania CM, Roberts RA, Callaway JB, Tilley SL, Ting JP. Characterization of NLRP12 during the development of allergic airway disease in mice. Plos One. 7: e30612. PMID 22291998 DOI: 10.1371/Journal.Pone.0030612  0.622
2012 Brickey WJ, Neuringer IP, Walton W, Hua X, Wang EY, Jha S, Sempowski GD, Yang X, Kirby SL, Tilley SL, Ting JP. MyD88 provides a protective role in long-term radiation-induced lung injury. International Journal of Radiation Biology. 88: 335-47. PMID 22248128 DOI: 10.3109/09553002.2012.652723  0.56
2012 Fry R, Zhou H, Zou B, Rager J, Brickey J, Ting J, Peden D, Alexis N. Inflammatory Gene Expression Differentiates With Airway Neutrophil Response To Ozone Journal of Allergy and Clinical Immunology. 129: AB139. DOI: 10.1016/J.Jaci.2011.12.467  0.307
2011 Roney KE, O'Connor BP, Wen H, Holl EK, Guthrie EH, Davis BK, Jones SW, Jha S, Sharek L, Garcia-Mata R, Bear JE, Ting JP. Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. Plos One. 6: e24795. PMID 21966369 DOI: 10.1371/Journal.Pone.0024795  0.808
2011 Barker BR, Taxman DJ, Ting JP. Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines. Current Opinion in Immunology. 23: 591-7. PMID 21839623 DOI: 10.1016/J.Coi.2011.07.005  0.807
2011 Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. Immunity. 34: 854-65. PMID 21703540 DOI: 10.1016/J.Immuni.2011.03.026  0.815
2011 Taxman DJ, Holley-Guthrie EA, Huang MT, Moore CB, Bergstralh DT, Allen IC, Lei Y, Gris D, Ting JP. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. The Journal of Biological Chemistry. 286: 19605-16. PMID 21487011 DOI: 10.1074/Jbc.M111.221077  0.797
2011 Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nature Immunology. 12: 408-15. PMID 21478880 DOI: 10.1038/Ni.2022  0.731
2011 Holl EK, O'Connor BP, Holl TM, Roney KE, Zimmermann AG, Jha S, Kelsoe G, Ting JP. Plexin-D1 is a novel regulator of germinal centers and humoral immune responses. Journal of Immunology (Baltimore, Md. : 1950). 186: 5603-11. PMID 21464091 DOI: 10.4049/Jimmunol.1003464  0.783
2011 Gregory SM, Davis BK, West JA, Taxman DJ, Matsuzawa S, Reed JC, Ting JP, Damania B. Discovery of a viral NLR homolog that inhibits the inflammasome. Science (New York, N.Y.). 331: 330-4. PMID 21252346 DOI: 10.1126/Science.1199478  0.3
2011 Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Cutting edge: NLRC5-dependent activation of the inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 186: 1333-7. PMID 21191067 DOI: 10.4049/Jimmunol.1003111  0.791
2011 McNally RS, Davis BK, Clements CM, Accavitti-Loper MA, Mak TW, Ting JP. DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB. The Journal of Biological Chemistry. 286: 4098-106. PMID 21097510 DOI: 10.1074/Jbc.M110.147371  0.807
2010 van Deventer HW, Burgents JE, Wu QP, Woodford RM, Brickey WJ, Allen IC, McElvania-Tekippe E, Serody JS, Ting JP. The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. Cancer Research. 70: 10161-9. PMID 21159638 DOI: 10.1158/0008-5472.Can-10-1921  0.542
2010 Jha S, Srivastava SY, Brickey WJ, Iocca H, Toews A, Morrison JP, Chen VS, Gris D, Matsushima GK, Ting JP. The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15811-20. PMID 21106820 DOI: 10.1523/Jneurosci.4088-10.2010  0.59
2010 Wen H, Lei Y, Eun SY, Ting JP. Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm. The Journal of Experimental Medicine. 207: 2943-57. PMID 21098092 DOI: 10.1084/jem.20101138  0.66
2010 Huang MT, Mortensen BL, Taxman DJ, Craven RR, Taft-Benz S, Kijek TM, Fuller JR, Davis BK, Allen IC, Brickey WJ, Gris D, Wen H, Kawula TH, Ting JP. Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. Journal of Immunology (Baltimore, Md. : 1950). 185: 5476-85. PMID 20921527 DOI: 10.4049/Jimmunol.1002154  0.604
2010 Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, Schneider M, Roney KE, O'Connor BP, Moore CB, Morrison A, Sutterwala FS, Bertin J, Koller BH, Liu Z, ... Ting JP, et al. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 185: 4515-9. PMID 20861349 DOI: 10.4049/Jimmunol.1002227  0.795
2010 McElvania Tekippe E, Allen IC, Hulseberg PD, Sullivan JT, McCann JR, Sandor M, Braunstein M, Ting JP. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. Plos One. 5: e12320. PMID 20808838 DOI: 10.1371/Journal.Pone.0012320  0.746
2010 Taxman DJ, Huang MT, Ting JP. Inflammasome inhibition as a pathogenic stealth mechanism. Cell Host & Microbe. 8: 7-11. PMID 20638636 DOI: 10.1016/j.chom.2010.06.005  0.573
2010 Gris D, Ye Z, Iocca HA, Wen H, Craven RR, Gris P, Huang M, Schneider M, Miller SD, Ting JP. NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 974-81. PMID 20574004 DOI: 10.4049/Jimmunol.0904145  0.752
2010 Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. The Journal of Experimental Medicine. 207: 1045-56. PMID 20385749 DOI: 10.1084/Jem.20100050  0.666
2010 Ting JP, Duncan JA, Lei Y. How the noninflammasome NLRs function in the innate immune system. Science (New York, N.Y.). 327: 286-90. PMID 20075243 DOI: 10.1126/science.1184004  0.467
2010 Wen H, Lei Y, Eun S, Ting J. Plexin-A4/Semaphorin 3A Signaling is Required for TLR- and Sepsis-induced Cytokine Storm Clinical Immunology. 135: S46. DOI: 10.1016/J.Clim.2010.03.141  0.581
2009 Jha S, Ting JP. Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases. Journal of Immunology (Baltimore, Md. : 1950). 183: 7623-9. PMID 20007570 DOI: 10.4049/Jimmunol.0902425  0.579
2009 Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. Plos One. 4: e7446. PMID 19826485 DOI: 10.1371/Journal.Pone.0007446  0.39
2009 Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 183: 2008-15. PMID 19587006 DOI: 10.4049/Jimmunol.0900138  0.806
2009 Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 182: 6460-9. PMID 19414800 DOI: 10.4049/Jimmunol.0802696  0.804
2009 Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. MAVS-mediated apoptosis and its inhibition by viral proteins. Plos One. 4: e5466. PMID 19404494 DOI: 10.1371/Journal.Pone.0005466  0.723
2009 Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30: 556-65. PMID 19362020 DOI: 10.1016/J.Immuni.2009.02.005  0.636
2009 Lord CA, Savitsky D, Sitcheran R, Calame K, Wright JR, Ting JP, Williams KL. Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1. Journal of Immunology (Baltimore, Md. : 1950). 182: 2948-58. PMID 19234190 DOI: 10.4049/Jimmunol.0801692  0.444
2009 Huang MT, Taxman DJ, Holley-Guthrie EA, Moore CB, Willingham SB, Madden V, Parsons RK, Featherstone GL, Arnold RR, O'Connor BP, Ting JP. Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 2395-404. PMID 19201894 DOI: 10.4049/Jimmunol.0800909  0.754
2008 O'Connor BP, Eun SY, Ye Z, Zozulya AL, Lich JD, Moore CB, Iocca HA, Roney KE, Holl EK, Wu QP, van Deventer HW, Fabry Z, Ting JP. Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 13015-20. PMID 18728195 DOI: 10.1073/Pnas.0803386105  0.791
2008 Willingham SB, Ting JP. NLRs and the dangers of pollution and aging. Nature Immunology. 9: 831-3. PMID 18645588 DOI: 10.1038/ni0808-831  0.56
2008 Li H, Willingham SB, Ting JP, Re F. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. Journal of Immunology (Baltimore, Md. : 1950). 181: 17-21. PMID 18566365  0.675
2008 van Deventer HW, Wu QP, Bergstralh DT, Davis BK, O'Connor BP, Ting JP, Serody JS. C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9. The American Journal of Pathology. 173: 253-64. PMID 18535183 DOI: 10.2353/Ajpath.2008.070732  0.732
2008 Ting JP, Willingham SB, Bergstralh DT. NLRs at the intersection of cell death and immunity. Nature Reviews. Immunology. 8: 372-9. PMID 18362948 DOI: 10.1038/Nri2296  0.809
2008 Ye Z, Ting JP. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Current Opinion in Immunology. 20: 3-9. PMID 18280719 DOI: 10.1016/J.Coi.2008.01.003  0.545
2008 Iocca HA, Plant SR, Wang Y, Runkel L, O'Connor BP, Lundsmith ET, Hahm K, van Deventer HW, Burkly LC, Ting JP. TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model. Journal of Neuroimmunology. 194: 97-106. PMID 18207576 DOI: 10.1016/J.Jneuroim.2007.12.003  0.747
2008 Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature. 451: 573-7. PMID 18200010 DOI: 10.1038/Nature06501  0.769
2008 Ye Z, Lich JD, Moore CB, Duncan JA, Williams KL, Ting JP. ATP binding by monarch-1/NLRP12 is critical for its inhibitory function. Molecular and Cellular Biology. 28: 1841-50. PMID 18160710 DOI: 10.1128/Mcb.01468-07  0.523
2007 Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host & Microbe. 2: 147-59. PMID 18005730 DOI: 10.1016/J.Chom.2007.07.009  0.804
2007 Duncan JA, Ting JP. Rebuilding host-pathogen interaction from the ground up: in vitro reconstitution of the inflammasome. Cell Host & Microbe. 1: 7-9. PMID 18005676 DOI: 10.1016/j.chom.2007.02.007  0.358
2007 Arthur JC, Lich JD, Aziz RK, Kotb M, Ting JP. Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase. Journal of Immunology (Baltimore, Md. : 1950). 179: 6291-6. PMID 17947705 DOI: 10.4049/Jimmunol.179.9.6291  0.632
2007 Plant SR, Iocca HA, Wang Y, Thrash JC, O'Connor BP, Arnett HA, Fu YX, Carson MJ, Ting JP. Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7429-37. PMID 17626203 DOI: 10.1523/Jneurosci.1307-07.2007  0.8
2007 Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, Ting JP. Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 8041-6. PMID 17483456 DOI: 10.1073/Pnas.0611496104  0.796
2007 Lich JD, Williams KL, Moore CB, Arthur JC, Davis BK, Taxman DJ, Ting JP. Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. Journal of Immunology (Baltimore, Md. : 1950). 178: 1256-60. PMID 17237370 DOI: 10.4049/Jimmunol.178.3.1256  0.641
2007 Bergstralh DT, Conti BJ, Moore CB, Brickey WJ, Taxman DJ, Ting JP. Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription. Experimental Cell Research. 313: 65-76. PMID 17069796 DOI: 10.1016/J.Yexcr.2006.09.016  0.801
2006 Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proceedings of the National Academy of Sciences of the United States of America. 103: 15091-6. PMID 17015834 DOI: 10.1073/Pnas.0607260103  0.78
2006 Eun SY, O'Connor BP, Wong AW, van Deventer HW, Taxman DJ, Reed W, Li P, Blum JS, McKinnon KP, Ting JP. Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 4271-5. PMID 16982860 DOI: 10.4049/Jimmunol.177.7.4271  0.708
2006 Taxman DJ, Zhang J, Champagne C, Bergstralh DT, Iocca HA, Lich JD, Ting JP. Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 177: 4252-6. PMID 16982856 DOI: 10.4049/Jimmunol.177.7.4252  0.725
2006 Lich JD, Arthur JC, Ting JP. Cryopyrin: in from the cold. Immunity. 24: 241-3. PMID 16546091 DOI: 10.1016/J.Immuni.2006.03.004  0.607
2006 Bergstralh DT, Ting JP. Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination. Cancer Treatment Reviews. 32: 166-79. PMID 16527420 DOI: 10.1016/J.Ctrv.2006.01.004  0.655
2006 Taxman DJ, Livingstone LR, Zhang J, Conti BJ, Iocca HA, Williams KL, Lich JD, Ting JP, Reed W. Criteria for effective design, construction, and gene knockdown by shRNA vectors. Bmc Biotechnology. 6: 7. PMID 16433925 DOI: 10.1186/1472-6750-6-7  0.692
2006 Plant SR, Wang Y, Vasseur S, Thrash JC, McMahon EJ, Bergstralh DT, Arnett HA, Miller SD, Carson MJ, Iovanna JL, Ting JP. Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues. Glia. 53: 529-37. PMID 16374777 DOI: 10.1002/Glia.20297  0.773
2005 Zika E, Fauquier L, Vandel L, Ting JP. Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 16321-6. PMID 16254053 DOI: 10.1073/Pnas.0505045102  0.752
2005 Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA, Su L, Vogel SN, Braunstein M, Ting JP. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. The Journal of Biological Chemistry. 280: 39914-24. PMID 16203735 DOI: 10.1074/Jbc.M502820200  0.307
2005 Wang AH, Grégoire S, Zika E, Xiao L, Li CS, Li H, Wright KL, Ting JP, Yang XJ. Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases. The Journal of Biological Chemistry. 280: 29117-27. PMID 15964851 DOI: 10.1074/Jbc.M500295200  0.765
2005 van Deventer HW, O'Connor W, Brickey WJ, Aris RM, Ting JP, Serody JS. C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis. Cancer Research. 65: 3374-9. PMID 15833871 DOI: 10.1158/0008-5472.Can-04-2616  0.695
2005 Conti BJ, Davis BK, Zhang J, O'connor W, Williams KL, Ting JP. CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function. The Journal of Biological Chemistry. 280: 18375-85. PMID 15705585 DOI: 10.1074/Jbc.M413169200  0.795
2005 Zika E, Ting JP. Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes. Current Opinion in Immunology. 17: 58-64. PMID 15653312 DOI: 10.1016/J.Coi.2004.11.008  0.732
2005 Plant SR, Arnett HA, Ting JP. Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination. Glia. 49: 1-14. PMID 15382206 DOI: 10.1002/Glia.20089  0.785
2005 Ting J. Genomic mining of new genes and pathways in innate and adaptive immunity. Novartis Foundation Symposium. 267: 231-241. DOI: 10.1002/047002139X.Ch15  0.361
2004 Bergstralh DT, Taxman DJ, Chou TC, Danishefsky SJ, Ting JP. A comparison of signaling activities induced by Taxol and desoxyepothilone B. Journal of Chemotherapy (Florence, Italy). 16: 563-76. PMID 15700849 DOI: 10.1179/Joc.2004.16.6.563  0.672
2004 Greer SF, Harton JA, Linhoff MW, Janczak CA, Ting JP, Cressman DE. Serine residues 286, 288, and 293 within the CIITA: a mechanism for down-regulating CIITA activity through phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 173: 376-83. PMID 15210796 DOI: 10.4049/Jimmunol.173.1.376  0.726
2004 Arancibia-Cárcamo CV, Osawa H, Arnett HA, Háskova Z, George AJ, Ono SJ, Ting JP, Streilein JW. A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites. European Journal of Immunology. 34: 471-80. PMID 14768052 DOI: 10.1002/eji.200324195  0.703
2003 O'Connor W, Harton JA, Zhu X, Linhoff MW, Ting JP. Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. Journal of Immunology (Baltimore, Md. : 1950). 171: 6329-33. PMID 14662828 DOI: 10.4049/Jimmunol.171.12.6329  0.805
2003 Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP. Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9824-32. PMID 14586011 DOI: 10.1523/Jneurosci.23-30-09824.2003  0.709
2003 MacKeigan JP, Clements CM, Lich JD, Pope RM, Hod Y, Ting JP. Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. Cancer Research. 63: 6928-34. PMID 14583493  0.789
2003 Greer SF, Zika E, Conti B, Zhu XS, Ting JP. Enhancement of CIITA transcriptional function by ubiquitin. Nature Immunology. 4: 1074-82. PMID 14528304 DOI: 10.1038/Ni985  0.785
2003 Taxman DJ, MacKeigan JP, Clements C, Bergstralh DT, Ting JP. Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor. Cancer Research. 63: 5095-104. PMID 12941840  0.789
2003 Wong AW, Brickey WJ, Taxman DJ, van Deventer HW, Reed W, Gao JX, Zheng P, Liu Y, Li P, Blum JS, McKinnon KP, Ting JP. CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions. Nature Immunology. 4: 891-8. PMID 12910265 DOI: 10.1038/Ni960  0.58
2003 Williams KL, Taxman DJ, Linhoff MW, Reed W, Ting JP. Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes. Journal of Immunology (Baltimore, Md. : 1950). 170: 5354-8. PMID 12759408 DOI: 10.4049/Jimmunol.170.11.5354  0.732
2003 Zika E, Greer SF, Zhu XS, Ting JP. Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation. Molecular and Cellular Biology. 23: 3091-102. PMID 12697811 DOI: 10.1128/Mcb.23.9.3091-3102.2003  0.78
2002 Harton JA, Linhoff MW, Zhang J, Ting JP. Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. Journal of Immunology (Baltimore, Md. : 1950). 169: 4088-93. PMID 12370334 DOI: 10.4049/Jimmunol.169.8.4088  0.717
2002 Wong AW, Ghosh N, McKinnon KP, Reed W, Piskurich JF, Wright KL, Ting JP. Regulation and specificity of MHC2TA promoter usage in human primary T lymphocytes and cell line. Journal of Immunology (Baltimore, Md. : 1950). 169: 3112-9. PMID 12218128 DOI: 10.4049/Jimmunol.169.6.3112  0.609
2002 van Deventer HW, Serody JS, McKinnon KP, Clements C, Brickey WJ, Ting JP. Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors. Journal of Immunology (Baltimore, Md. : 1950). 169: 1634-9. PMID 12133994 DOI: 10.4049/Jimmunol.169.3.1634  0.627
2002 MacKeigan JP, Taxman DJ, Hunter D, Earp HS, Graves LM, Ting JP. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2091-9. PMID 12114408  0.749
2002 Harton JA, O'Connor W, Conti BJ, Linhoff MW, Ting JP. Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation. Human Immunology. 63: 588-601. PMID 12072194 DOI: 10.1016/S0198-8859(02)00400-7  0.789
2002 Arnett HA, Hellendall RP, Matsushima GK, Suzuki K, Laubach VE, Sherman P, Ting JP. The protective role of nitric oxide in a neurotoxicant-induced demyelinating model. Journal of Immunology (Baltimore, Md. : 1950). 168: 427-33. PMID 11751989 DOI: 10.4049/Jimmunol.168.1.427  0.7
2001 Morrison TE, Mauser A, Wong A, Ting JP, Kenney SC. Inhibition of IFN-gamma signaling by an Epstein-Barr virus immediate-early protein. Immunity. 15: 787-99. PMID 11728340 DOI: 10.1016/S1074-7613(01)00226-6  0.603
2001 Arnett HA, Mason J, Marino M, Suzuki K, Matsushima GK, Ting JP. TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. Nature Neuroscience. 4: 1116-22. PMID 11600888 DOI: 10.1038/Nn738  0.671
2001 Zhu XS, Ting JP. A 36-amino-acid region of CIITA is an effective inhibitor of CBP: novel mechanism of gamma interferon-mediated suppression of collagen alpha(2)(I) and other promoters. Molecular and Cellular Biology. 21: 7078-88. PMID 11564890 DOI: 10.1128/Mcb.21.20.7078-7088.2001  0.515
2001 Cressman DE, O'Connor WJ, Greer SF, Zhu XS, Ting JP. Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator. Journal of Immunology (Baltimore, Md. : 1950). 167: 3626-34. PMID 11564775 DOI: 10.4049/Jimmunol.167.7.3626  0.464
2001 Harton JA, Zika E, Ting JP. The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivator. The Journal of Biological Chemistry. 276: 38715-20. PMID 11514574 DOI: 10.1074/Jbc.M106652200  0.761
2001 Deffrennes V, Vedrenne J, Stolzenberg MC, Piskurich J, Barbieri G, Ting JP, Charron D, Alcaïde-Loridan C. Constitutive expression of MHC class II genes in melanoma cell lines results from the transcription of class II transactivator abnormally initiated from its B cell-specific promoter. Journal of Immunology (Baltimore, Md. : 1950). 167: 98-106. PMID 11418637 DOI: 10.4049/Jimmunol.167.1.98  0.371
2001 Li G, Harton JA, Zhu X, Ting JP. Downregulation of CIITA function by protein kinase a (PKA)-mediated phosphorylation: mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines. Molecular and Cellular Biology. 21: 4626-35. PMID 11416140 DOI: 10.1128/Mcb.21.14.4626-4635.2001  0.48
2001 Linhoff MW, Harton JA, Cressman DE, Martin BK, Ting JP. Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains. Molecular and Cellular Biology. 21: 3001-11. PMID 11287606 DOI: 10.1128/Mcb.21.9.3001-3011.2001  0.716
2001 Raval A, Howcroft TK, Weissman JD, Kirshner S, Zhu XS, Yokoyama K, Ting J, Singer DS. Transcriptional coactivator, CIITA, is an acetyltransferase that bypasses a promoter requirement for TAF(II)250. Molecular Cell. 7: 105-15. PMID 11172716 DOI: 10.1016/S1097-2765(01)00159-9  0.538
2000 MacKeigan JP, Collins TS, Ting JP. MEK inhibition enhances paclitaxel-induced tumor apoptosis. The Journal of Biological Chemistry. 275: 38953-6. PMID 11038347 DOI: 10.1074/Jbc.C000684200  0.759
2000 Zhu XS, Linhoff MW, Li G, Chin KC, Maity SN, Ting JP. Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter. Molecular and Cellular Biology. 20: 6051-61. PMID 10913187 DOI: 10.1128/Mcb.20.16.6051-6061.2000  0.768
1999 Ting JP, Zhu XS. Class II MHC genes: a model gene regulatory system with great biologic consequences. Microbes and Infection / Institut Pasteur. 1: 855-61. PMID 10614002 DOI: 10.1016/S1286-4579(99)00233-6  0.492
1999 Brickey WJ, Wright KL, Zhu XS, Ting JP. Analysis of the defect in IFN-gamma induction of MHC class II genes in G1B cells: identification of a novel and functionally critical leucine-rich motif (62-LYLYLQL-68) in the regulatory factor X 5 transcription factor. Journal of Immunology (Baltimore, Md. : 1950). 163: 6622-30. PMID 10586057  0.491
1999 Piskurich JF, Linhoff MW, Wang Y, Ting JP. Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta. Molecular and Cellular Biology. 19: 431-40. PMID 9858567 DOI: 10.1128/MCB.19.1.431  0.729
1998 Hiremath MM, Saito Y, Knapp GW, Ting JP, Suzuki K, Matsushima GK. Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice. Journal of Neuroimmunology. 92: 38-49. PMID 9916878 DOI: 10.1016/S0165-5728(98)00168-4  0.33
1998 Lee LF, Li G, Templeton DJ, Ting JP. Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK). The Journal of Biological Chemistry. 273: 28253-60. PMID 9774447 DOI: 10.1074/jbc.273.43.28253  0.305
1998 Wright KL, Chin KC, Linhoff M, Skinner C, Brown JA, Boss JM, Stark GR, Ting JP. CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 6267-72. PMID 9600954 DOI: 10.1073/Pnas.95.11.6267  0.732
1998 White CM, Martin BK, Lee LF, Haskill JS, Ting JP. Effects of paclitaxel on cytokine synthesis by unprimed human monocytes, T lymphocytes, and breast cancer cells. Cancer Immunology, Immunotherapy : Cii. 46: 104-12. PMID 9558006 DOI: 10.1007/S002620050468  0.564
1998 Piskurich JF, Wang Y, Linhoff MW, White LC, Ting JP. Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene. Journal of Immunology (Baltimore, Md. : 1950). 160: 233-40. PMID 9551976  0.734
1997 Lee LF, Haskill JS, Mukaida N, Matsushima K, Ting JP. Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter. Molecular and Cellular Biology. 17: 5097-105. PMID 9271387 DOI: 10.1128/MCB.17.9.5097  0.303
1997 Linhoff MW, Wright KL, Ting JP. CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: the invariant chain promoter as a model. Molecular and Cellular Biology. 17: 4589-96. PMID 9234716  0.699
1996 Lee LF, Schuerer-Maly CC, Lofquist AK, van Haaften-Day C, Ting JP, White CM, Martin BK, Haskill JS. Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer. Cancer Research. 56: 1303-8. PMID 8640818  0.591
1994 Brown AM, Linhoff MW, Stein B, Wright KL, Baldwin AS, Basta PV, Ting JP. Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits. Molecular and Cellular Biology. 14: 2926-35. PMID 8164652 DOI: 10.1128/Mcb.14.5.2926  0.714
1994 Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 78: 645-56. PMID 8069913 DOI: 10.1016/0092-8674(94)90529-0  0.524
1992 Panek RB, Moses H, Ting JP, Benveniste EN. Tumor necrosis factor alpha response elements in the HLA-DRA promoter: identification of a tumor necrosis factor alpha-induced DNA-protein complex in astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 11518-22. PMID 1454841 DOI: 10.1073/Pnas.89.23.11518  0.341
1992 Matsushima GK, Itoh-Lindstrom Y, Ting JP. Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements. Molecular and Cellular Biology. 12: 5610-9. PMID 1448091 DOI: 10.1128/mcb.12.12.5610-5619.1992  0.356
1987 Ting JP, Takiguchi M, Macchi M, Frelinger JA. The expression and detection of MHC class I antigens on murine neuroblastoma and ependymoblastoma lines. Journal of Neuroimmunology. 14: 87-98. PMID 3492512 DOI: 10.1016/0165-5728(87)90103-2  0.462
1985 Takiguchi M, Ting JP, Buessow SC, Boyer C, Gillespie Y, Frelinger JA. Response of glioma cells to interferon-gamma: increase in class II RNA, protein and mixed lymphocyte reaction-stimulating ability. European Journal of Immunology. 15: 809-14. PMID 2411569 DOI: 10.1002/Eji.1830150813  0.506
1983 Ting JP, Nixon DF, Weiner LP, Frelinger JA. Brain Ia antigens have a bone marrow origin. Immunogenetics. 17: 295-301. PMID 6572615 DOI: 10.1007/BF00364413  0.43
1982 Nixon DF, Ting JP, Frelinger JA. Ia antigens on non-lymphoid tissues their origins and functions. Immunology Today. 3: 339-42. PMID 25290677 DOI: 10.1016/0167-5699(82)90019-6  0.488
1981 Ting JP, Shigekawa BL, Linthicum DS, Weiner LP, Frelinger JA. Expression and synthesis of murine immune response-associated (Ia) antigens by brain cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 3170-4. PMID 6166944 DOI: 10.1073/pnas.78.5.3170  0.489
Low-probability matches (unlikely to be authored by this person)
2014 Eitas TK, Chou WC, Wen H, Gris D, Robbins GR, Brickey J, Oyama Y, Ting JP. The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation. The Journal of Biological Chemistry. 289: 4173-9. PMID 24366868 DOI: 10.1074/Jbc.M113.533034  0.3
1987 Basta P, Sherman P, Ting J. Molecular identification of regulatory DNA sequences for basal and gamma-inteferon induced expression of HLA DRα in human multiforme glioblastoma cell lines Journal of Neuroimmunology. 16: 15. DOI: 10.1016/0165-5728(87)90152-4  0.299
2024 Kang HR, Han JH, Ng YC, Ryu S, Park JY, Chung WC, Song YJ, Chen ST, Brickey WJ, Ting JP, Song MJ. Dynamic bidirectional regulation of NLRC3 and gammaherpesviruses during viral latency in B lymphocytes. Journal of Medical Virology. 96: e29504. PMID 38445794 DOI: 10.1002/jmv.29504  0.298
1990 Evans JL, Moore TL, Kuehl WM, Bender T, Ting JP. Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter. Molecular and Cellular Biology. 10: 5747-52. PMID 2233716 DOI: 10.1128/mcb.10.11.5747-5752.1990  0.298
1987 Ting J, Sherman P, Yokota S, Boyer C, Basta P. Neurotransmitter modulation of the human class II gene DRα on multiforme glioblastoma cell lines: A molecular analysis Journal of Neuroimmunology. 16: 170. DOI: 10.1016/0165-5728(87)90394-8  0.296
2012 Razani B, Feng C, Coleman T, Emanuel R, Wen H, Hwang S, Ting JP, Virgin HW, Kastan MB, Semenkovich CF. Autophagy links inflammasomes to atherosclerotic progression. Cell Metabolism. 15: 534-44. PMID 22440612 DOI: 10.1016/J.Cmet.2012.02.011  0.295
2011 Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annual Review of Immunology. 29: 707-35. PMID 21219188 DOI: 10.1146/annurev-immunol-031210-101405  0.295
2019 Swanson KV, Deng M, Ting JP. The NLRP3 inflammasome: molecular activation and regulation to therapeutics. Nature Reviews. Immunology. PMID 31036962 DOI: 10.1038/s41577-019-0165-0  0.294
2013 Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, et al. Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 190: 5722-30. PMID 23630357 DOI: 10.4049/Jimmunol.1203343  0.293
1989 Ting J, Sherman P, Yokota S, Moore T, Basta P. Neurotransmitter modulation of the human class II gene DR alpha on multiforme glioblastoma cell lines. A molecular analysis. Annals of the New York Academy of Sciences. 540: 477-8. PMID 2849898 DOI: 10.1111/j.1749-6632.1988.tb27141.x  0.292
2011 Smith MA, Wright G, Wu J, Tailor P, Ozato K, Chen X, Wei S, Piskurich JF, Ting JP, Wright KL. Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation. The Journal of Biological Chemistry. 286: 7893-904. PMID 21216962 DOI: 10.1074/Jbc.M110.165431  0.29
2002 Chalermskulrat W, Neuringer IP, Ting JP, Felix NJ, Randell SH, Hathwar VK, Aris RM. Alloantigen recognition in the mouse heterotopic model of OB Journal of Heart and Lung Transplantation. 21: 131. DOI: 10.1016/S1053-2498(01)00645-3  0.289
2009 Ting J. NLR genes and adaptive and innate immunity Cytokine. 48: 36. DOI: 10.1016/J.Cyto.2009.07.337  0.289
2005 Reiman R, Campos Torres A, Martin BK, Ting JP, Campbell IL, Barnum SR. Expression of C5a in the brain does not exacerbate experimental autoimmune encephalomyelitis. Neuroscience Letters. 390: 134-8. PMID 16154690 DOI: 10.1016/J.Neulet.2005.08.022  0.286
2006 McIntosh K, Zvonic S, Garrett S, Mitchell JB, Floyd ZE, Hammill L, Kloster A, Di Halvorsen Y, Ting JP, Storms RW, Goh B, Kilroy G, Wu X, Gimble JM. The immunogenicity of human adipose-derived cells: temporal changes in vitro. Stem Cells (Dayton, Ohio). 24: 1246-53. PMID 16410391 DOI: 10.1634/Stemcells.2005-0235  0.285
2021 Johnson BM, Uchimura T, Gallovic MD, Thamilarasan M, Chou WC, Gibson SA, Deng M, Tam JW, Batty CJ, Williams J, Matsushima GK, Bachelder EM, Ainslie KM, Markovic-Plese S, Ting JP. STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways. Journal of Immunology (Baltimore, Md. : 1950). PMID 33820855 DOI: 10.4049/jimmunol.2001317  0.285
2017 Feng H, Lenarcic EM, Yamane D, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, Lemon SM. NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR. Nature Immunology. PMID 28967880 DOI: 10.1038/Ni.3853  0.285
2003 Chalermskulrat W, Neuringer IP, Brickey WJ, Felix NJ, Randell SH, Ting JP, Aris RM. Hierarchical contributions of allorecognition pathways in chronic lung rejection. American Journal of Respiratory and Critical Care Medicine. 167: 999-1007. PMID 12446274 DOI: 10.1164/rccm.200209-1099OC  0.283
2024 Koller BH, Nguyen M, Snouwaert JN, Gabel CA, Ting JP. Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases. Cell Reports. 43: 113852. PMID 38427558 DOI: 10.1016/j.celrep.2024.113852  0.28
2013 Steinbach EC, Kobayashi T, Mishima Y, Liu B, Sartor RB, Ting JP, Plevy SE. 738 The Phosphoinositide 3-Kinase Subunit P1105 Regulates TH1/TH17 Skewing in Murine and Human IBD Gastroenterology. 144: S-133. DOI: 10.1016/S0016-5085(13)60478-3  0.277
2014 Giguère PM, Gall BJ, Ezekwe EA, Laroche G, Buckley BK, Kebaier C, Wilson JE, Ting JP, Siderovski DP, Duncan JA. G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3. The Journal of Biological Chemistry. 289: 33245-57. PMID 25271165 DOI: 10.1074/Jbc.M114.578393  0.274
1988 Basta P, Sherman P, Ting J. Molecular Identification of Regulatory DNA Sequences for Basal and Gamma‐Interferon‐Induced Expression of HLA DRα in Human Multiforme Glioblastoma Cell Lines Annals of the New York Academy of Sciences. 540: 255-257. PMID 2849892 DOI: 10.1111/J.1749-6632.1988.Tb27068.X  0.273
2016 Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, ... ... Ting JP, et al. NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses. Cell Host & Microbe. 19: 515-528. PMID 27078069 DOI: 10.1016/J.Chom.2016.03.001  0.272
1999 Nikcevich KM, Piskurich JF, Hellendall RP, Wang Y, Ting JP. Differential selectivity of CIITA promoter activation by IFN-gamma and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-alpha. Journal of Neuroimmunology. 99: 195-204. PMID 10505975 DOI: 10.1016/S0165-5728(99)00117-4  0.27
2016 Koblansky AA, Truax AD, Liu R, Montgomery SA, Ding S, Wilson JE, Brickey WJ, Mühlbauer M, McFadden RT, Hu P, Li Z, Jobin C, Lund PK, Ting JP. The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals. Cell Reports. PMID 26971998 DOI: 10.1016/J.Celrep.2016.02.064  0.269
2014 Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE. Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis. Journal of Immunology (Baltimore, Md. : 1950). 192: 3958-68. PMID 24634494 DOI: 10.4049/Jimmunol.1301533  0.269
2017 Swanson KV, Junkins RD, Kurkjian CJ, Holley-Guthrie E, Pendse AA, El Morabiti R, Petrucelli A, Barber GN, Benedict CA, Ting JP. A noncanonical function of cGAMP in inflammasome priming and activation. The Journal of Experimental Medicine. PMID 29030458 DOI: 10.1084/Jem.20171749  0.268
2000 Collins TS, Lee LF, Ting JP. Paclitaxel up-regulates interleukin-8 synthesis in human lung carcinoma through an NF-kappaB- and AP-1-dependent mechanism. Cancer Immunology, Immunotherapy : Cii. 49: 78-84. PMID 10823417 DOI: 10.1007/s002620050605  0.266
1991 Cogswell JP, Zeleznik-Le N, Ting JP. Transcriptional regulation of the HLA-DRA gene. Critical Reviews in Immunology. 11: 87-112. PMID 1930684  0.264
2021 Chou WC, Guo Z, Guo H, Chen L, Zhang G, Liang K, Xie L, Tan X, Gibson SA, Rampanelli E, Wang Y, Montgomery SA, Brickey WJ, Deng M, Freeman L, ... ... Ting JP, et al. AIM2 in regulatory T cells restrains autoimmune diseases. Nature. PMID 33505023 DOI: 10.1038/s41586-021-03231-w  0.263
2012 Taxman DJ, Lei Y, Zhang S, Holley-Guthrie E, Offenbacher S, Ting JP. ASC-dependent RIP2 kinase regulates reduced PGE2 production in chronic periodontitis. Journal of Dental Research. 91: 877-82. PMID 22828789 DOI: 10.1177/0022034512454541  0.262
2012 Kobayashi T, Matsuoka K, Sheikh SZ, Russo SM, Mishima Y, Collins C, deZoeten EF, Karp CL, Ting JP, Sartor RB, Plevy SE. IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 189: 1792-9. PMID 22786766 DOI: 10.4049/Jimmunol.1200042  0.262
1999 Itoh-Lindstrom Y, Piskurich JF, Felix NJ, Wang Y, Brickey WJ, Platt JL, Koller BH, Ting JP. Reduced IL-4-, lipopolysaccharide-, and IFN-gamma-induced MHC class II expression in mice lacking class II transactivator due to targeted deletion of the GTP-binding domain. Journal of Immunology (Baltimore, Md. : 1950). 163: 2425-31. PMID 10452977  0.262
2011 Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N. Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner. Blood. 118: 2366-74. PMID 21700772 DOI: 10.1182/Blood-2011-01-330878  0.262
2024 Wang Y, Li S, Hu M, Yang Y, McCabe E, Zhang L, Withrow AM, Ting JP, Liu R. Universal STING mimic boosts antitumour immunity via preferential activation of tumour control signalling pathways. Nature Nanotechnology. PMID 38480836 DOI: 10.1038/s41565-024-01624-2  0.261
2012 Mendoza A, Brickey W, Neely C, Ting J, Maile R, Cairns B. Radiation Combined With Thermal Injury Results in Specific Alterations in Adaptive and Innate Immune Cell Populations Journal of Surgical Research. 172: 259-260. DOI: 10.1016/J.Jss.2011.11.422  0.261
1999 Ghosh N, Piskurich JF, Wright G, Hassani K, Ting JP, Wright KL. A novel element and a TEF-2-like element activate the major histocompatibility complex class II transactivator in B-lymphocytes. The Journal of Biological Chemistry. 274: 32342-50. PMID 10542275 DOI: 10.1074/jbc.274.45.32342  0.259
2005 Ting JP, Williams KL. The CATERPILLER family: an ancient family of immune/apoptotic proteins. Clinical Immunology (Orlando, Fla.). 115: 33-7. PMID 15870018 DOI: 10.1016/J.Clim.2005.02.007  0.258
2016 Snouwaert JN, Nguyen M, Repenning PW, Dye R, Livingston EW, Kovarova M, Moy SS, Brigman BE, Bateman TA, Ting JP, Koller BH. An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice. Cell Reports. 17: 3077-3088. PMID 27974218 DOI: 10.1016/J.Celrep.2016.11.052  0.258
2013 Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM. Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells. Plos Pathogens. 9: e1003256. PMID 23592984 DOI: 10.1371/journal.ppat.1003256  0.256
2019 Deng M, Guo H, Tam JW, Johnson BM, Brickey WJ, New JS, Lenox A, Shi H, Golenbock DT, Koller BH, McKinnon KP, Beutler B, Ting JP. Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR. The Journal of Experimental Medicine. PMID 31558613 DOI: 10.1084/Jem.20190111  0.255
2015 Knight ER, Patel EY, Flowers CA, Crowther AJ, Ting JP, Miller CR, Gershon TR, Deshmukh M. ASC deficiency suppresses proliferation and prevents medulloblastoma incidence. Oncogene. 34: 394-402. PMID 24469054 DOI: 10.1038/Onc.2013.577  0.254
2008 O'Connor BP, Ting JP. The evolving role of semaphorins and plexins in the immune system: Plexin-A1 regulation of dendritic cell function. Immunologic Research. 41: 217-22. PMID 18649144 DOI: 10.1007/s12026-008-8026-0  0.254
2017 Ma Z, Hopcraft SE, Yang F, Petrucelli A, Guo H, Ting JP, Dittmer DP, Damania B. NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency. Plos Pathogens. 13: e1006350. PMID 28459883 DOI: 10.1371/Journal.Ppat.1006350  0.254
2015 Freeman LC, Ting JP. The pathogenic role of the inflammasome in neurodegenerative diseases. Journal of Neurochemistry. PMID 26119245 DOI: 10.1111/jnc.13217  0.253
2023 Seyedsadr M, Wang Y, Elzoheiry M, Shree Gopal S, Jang S, Duran G, Chervoneva I, Kasimoglou E, Wrobel JA, Hwang D, Garifallou J, Zhang X, Khan TH, Lorenz U, Su M, ... Ting JP, et al. IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221007120. PMID 37339207 DOI: 10.1073/pnas.2221007120  0.253
1997 Hellendall RP, Ting JP. Differential regulation of cytokine-induced major histocompatibility complex class II expression and nitric oxide release in rat microglia and astrocytes by effectors of tyrosine kinase, protein kinase C, and cAMP. Journal of Neuroimmunology. 74: 19-29. PMID 9119973 DOI: 10.1016/S0165-5728(96)00202-0  0.252
2017 Chang TH, Huang JH, Lin HC, Chen WY, Lee YH, Hsu LC, Netea MG, Ting JP, Wu-Hsieh BA. Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum. Plos Pathogens. 13: e1006485. PMID 28671985 DOI: 10.1371/journal.ppat.1006485  0.252
2000 Harton JA, Ting JP. Class II transactivator: mastering the art of major histocompatibility complex expression. Molecular and Cellular Biology. 20: 6185-94. PMID 10938095 DOI: 10.1128/Mcb.20.17.6185-6194.2000  0.252
2008 Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, Baldwin AS. Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes & Development. 22: 1490-500. PMID 18519641 DOI: 10.1101/Gad.1662308  0.25
1996 White LC, Wright KL, Felix NJ, Ruffner H, Reis LF, Pine R, Ting JP. Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice. Immunity. 5: 365-76. PMID 8885869 DOI: 10.1016/S1074-7613(00)80262-9  0.25
2015 Aachoui Y, Kajiwara Y, Leaf IA, Mao D, Ting JP, Coers J, Aderem A, Buxbaum JD, Miao EA. Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium. Cell Host & Microbe. 18: 320-32. PMID 26320999 DOI: 10.1016/J.Chom.2015.07.016  0.25
1997 Zimmermann AG, Wright KL, Ting JP, Mitchell BS. Regulation of inosine-5'-monophosphate dehydrogenase type II gene expression in human T cells. Role for a novel 5' palindromic octamer sequence. The Journal of Biological Chemistry. 272: 22913-23. PMID 9278455 DOI: 10.1074/jbc.272.36.22913  0.248
1992 Zeleznik-Le NJ, Itoh-Lindstrom Y, Clarke JB, Moore TL, Ting JP. The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA. The Journal of Biological Chemistry. 267: 7677-82. PMID 1560002  0.248
1993 Brown AM, Wright KL, Ting JP. Human major histocompatibility complex class II-associated invariant chain gene promoter. Functional analysis and in vivo protein/DNA interactions of constitutive and IFN-gamma-induced expression. The Journal of Biological Chemistry. 268: 26328-33. PMID 8253755  0.248
1995 Wright KL, White LC, Kelly A, Beck S, Trowsdale J, Ting JP. Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. The Journal of Experimental Medicine. 181: 1459-71. PMID 7699330 DOI: 10.1084/jem.181.4.1459  0.248
2021 Cai D, Brickey WJ, Ting JP, Sad S. Isolates of Salmonella typhimurium circumvent NLRP3 inflammasome recognition in macrophages during the chronic phase of infection. The Journal of Biological Chemistry. 298: 101461. PMID 34864057 DOI: 10.1016/j.jbc.2021.101461  0.247
2016 Coutermarsh-Ott S, Simmons A, Capria V, LeRoith T, Wilson JE, Heid B, Philipson CW, Qin Q, Hontecillas-Magarzo R, Bassaganya-Riera J, Ting JP, Dervisis N, Allen IC. NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling. Oncotarget. PMID 27105514 DOI: 10.18632/Oncotarget.8861  0.247
1987 Basta PV, Sherman PA, Ting JP. Identification of an interferon-gamma response region 5' of the human histocompatibility leukocyte antigen DR alpha chain gene which is active in human glioblastoma multiforme lines. Journal of Immunology (Baltimore, Md. : 1950). 138: 1275-80. PMID 3027177  0.247
1998 Montani V, Taniguchi SI, Shong M, Suzuki K, Ohmori M, Giuliani C, Napolitano G, Saji M, Fiorentino B, Reimold AM, Ting JP, Kohn LD, Singer DS. Major histocompatibility class II HLA-DR alpha gene expression in thyrocytes: counter regulation by the class II transactivator and the thyroid Y box protein. Endocrinology. 139: 280-9. PMID 9421426 DOI: 10.1210/Endo.139.1.5673  0.246
2003 Repique CJ, Li A, Brickey WJ, Ting JP, Collins FM, Morris SL. Susceptibility of mice deficient in the MHC class II transactivator to infection with Mycobacterium tuberculosis. Scandinavian Journal of Immunology. 58: 15-22. PMID 12828554 DOI: 10.1046/j.1365-3083.2003.01266.x  0.245
2020 Guo H, Ting JP. Inflammasome Assays In Vitro and in Mouse Models. Current Protocols in Immunology. 131: e107. PMID 33017103 DOI: 10.1002/cpim.107  0.245
2015 Krauss JL, Zeng R, Hickman-Brecks CL, Wilson JE, Ting JP, Novack DV. NLRP12 provides a critical checkpoint for osteoclast differentiation. Proceedings of the National Academy of Sciences of the United States of America. 112: 10455-60. PMID 26240332 DOI: 10.1073/pnas.1500196112  0.244
2008 Hiremath MM, Chen VS, Suzuki K, Ting JP, Matsushima GK. MHC class II exacerbates demyelination in vivo independently of T cells. Journal of Neuroimmunology. 203: 23-32. PMID 18805594 DOI: 10.1016/J.Jneuroim.2008.06.034  0.244
1991 Zeleznik-Le NJ, Azizkhan JC, Ting JP. Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene. Proceedings of the National Academy of Sciences of the United States of America. 88: 1873-7. PMID 1848012  0.242
1989 Sherman PA, Basta PV, Moore TL, Brown AM, Ting JP. Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins. Molecular and Cellular Biology. 9: 50-6. PMID 2538724 DOI: 10.1128/mcb.9.1.50-56.1989  0.241
2000 Piskurich JF, Lin KI, Lin Y, Wang Y, Ting JP, Calame K. BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells. Nature Immunology. 1: 526-32. PMID 11101876 DOI: 10.1038/82788  0.24
1997 Chin KC, Li GG, Ting JP. Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants. Proceedings of the National Academy of Sciences of the United States of America. 94: 2501-6. PMID 9122224 DOI: 10.1073/PNAS.94.6.2501  0.24
2023 Snouwaert JN, Jania LA, Nguyen T, Martinez DR, Schäfer A, Catanzaro NJ, Gully KL, Baric RS, Heise M, Ferris MT, Anderson E, Pressey K, Dillard JA, Taft-Benz S, Baxter VK, ... Ting JP, et al. Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements. Plos Pathogens. 19: e1011168. PMID 36812267 DOI: 10.1371/journal.ppat.1011168  0.238
2012 Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S. TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. Plos One. 7: e29695. PMID 22295065 DOI: 10.1371/Journal.Pone.0029695  0.238
2023 Barnett KC, Li S, Liang K, Ting JP. A 360° view of the inflammasome: Mechanisms of activation, cell death, and diseases. Cell. 186: 2288-2312. PMID 37236155 DOI: 10.1016/j.cell.2023.04.025  0.238
2013 Wen H, Ting JP. Agitation by suffocation: how hypoxia activates innate immunity via the Warburg effect. Cell Metabolism. 17: 814-5. PMID 23747241 DOI: 10.1016/j.cmet.2013.05.016  0.238
1994 Panek RB, Lee YJ, Itoh-Lindstrom Y, Ting JP, Benveniste EN. Characterization of astrocyte nuclear proteins involved in IFN-gamma- and TNF-alpha-mediated class II MHC gene expression. Journal of Immunology (Baltimore, Md. : 1950). 153: 4555-64. PMID 7963527  0.235
1992 Wright KL, Ting JP. In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma. Proceedings of the National Academy of Sciences of the United States of America. 89: 7601-5. PMID 1502171 DOI: 10.1073/PNAS.89.16.7601  0.235
2005 Ting J. Genomic mining of new genes and pathways in innate and adaptive immunity. Novartis Foundation Symposium. 267: 231-9; discussion 23. PMID 15999810  0.234
2005 Ting JP, Davis BK. CATERPILLER: a novel gene family important in immunity, cell death, and diseases. Annual Review of Immunology. 23: 387-414. PMID 15771576 DOI: 10.1146/annurev.immunol.23.021704.115616  0.234
1993 Ting JP, Baldwin AS. Regulation of MHC gene expression. Current Opinion in Immunology. 5: 8-16. PMID 8452678 DOI: 10.1016/0952-7915(93)90074-3  0.234
2017 O'Brien M, Moehring D, Muñoz-Planillo R, Núñez G, Callaway J, Ting J, Scurria M, Ugo T, Bernad L, Cali J, Lazar D. A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells. Journal of Immunological Methods. PMID 28268194 DOI: 10.1016/J.Jim.2017.03.004  0.234
1994 Ting JP, Painter A, Zeleznik-Le NJ, MacDonald G, Moore TM, Brown A, Schwartz BD. YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes. The Journal of Experimental Medicine. 179: 1605-11. PMID 8163940  0.233
2008 Bhat KP, Turner JD, Myers SE, Cape AD, Ting JP, Greer SF. The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription. Molecular Immunology. 45: 2214-24. PMID 18215421 DOI: 10.1016/j.molimm.2007.12.001  0.232
2017 Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nature Immunology. PMID 28288099 DOI: 10.1038/Ni.3690  0.232
2006 Moore CB, Medina MA, Van Deventer HW, O’Connor BP, Cameron S, Ting J, Cairns BA. Increasing Burn Size Dramatically Influences the Immune Response to Burn Injury Journal of Burn Care & Research. 27: S127. DOI: 10.1097/01253092-200603001-00158  0.232
1991 Cogswell JP, Austin J, Ting JP. The W element is a positive regulator of HLA-DRA transcription in various DR+ cell types. Journal of Immunology (Baltimore, Md. : 1950). 146: 1361-7. PMID 1991973  0.231
2015 Callaway JB, Smith SA, McKinnon KP, de Silva AM, Crowe JE, Ting JP. Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. The Journal of Biological Chemistry. 290: 17306-20. PMID 26032420 DOI: 10.1074/jbc.M115.664136  0.229
2000 Chatterjee-Kishore M, Wright KL, Ting JP, Stark GR. How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene. The Embo Journal. 19: 4111-22. PMID 10921891 DOI: 10.1093/emboj/19.15.4111  0.227
1990 Sasaki A, Levison SW, Ting JP. Differential suppression of interferon-gamma-induced Ia antigen expression on cultured rat astroglia and microglia by second messengers. Journal of Neuroimmunology. 29: 213-22. PMID 2170439 DOI: 10.1016/0165-5728(90)90164-I  0.226
1995 Wright KL, Moore TL, Vilen BJ, Brown AM, Ting JP. Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y. The Journal of Biological Chemistry. 270: 20978-86. PMID 7673122 DOI: 10.1074/jbc.270.36.20978  0.226
1994 Chin KC, Mao C, Skinner C, Riley JL, Wright KL, Moreno CS, Stark GR, Boss JM, Ting JP. Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction. Immunity. 1: 687-97. PMID 7600294 DOI: 10.1016/1074-7613(94)90039-6  0.226
1990 Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science (New York, N.Y.). 247: 1581-4. PMID 2321018 DOI: 10.1126/Science.2321018  0.225
2023 Au KM, Wilson JE, Ting JP, Wang AZ. An injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis. Nature Biomedical Engineering. PMID 38049469 DOI: 10.1038/s41551-023-01136-9  0.225
2000 Lee LF, Hellendall RP, Wang Y, Haskill JS, Mukaida N, Matsushima K, Ting JP. IL-8 reduced tumorigenicity of human ovarian cancer in vivo due to neutrophil infiltration. Journal of Immunology (Baltimore, Md. : 1950). 164: 2769-75. PMID 10679119  0.224
1989 Sherman PA, Basta PV, Heguy A, Wloch MK, Roeder RG, Ting JP. The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter. Proceedings of the National Academy of Sciences of the United States of America. 86: 6739-43. PMID 2505259 DOI: 10.1073/PNAS.86.17.6739  0.224
2011 Jorgensen I, Bednar MM, Amin V, Davis BK, Ting JP, McCafferty DG, Valdivia RH. The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. Cell Host & Microbe. 10: 21-32. PMID 21767809 DOI: 10.1016/J.Chom.2011.06.008  0.223
2022 Lee EJ, Napier RJ, Vance EE, Lashley SJ, Truax AD, Ting JP, Rosenzweig HL. The innate immune receptor Nlrp12 suppresses autoimmunity to the retina. Journal of Neuroinflammation. 19: 69. PMID 35313917 DOI: 10.1186/s12974-022-02425-x  0.223
2012 Wen H, Ting JP, O'Neill LA. A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation? Nature Immunology. 13: 352-7. PMID 22430788 DOI: 10.1038/ni.2228  0.223
2006 Chalermskulrat W, McKinnon KP, Brickey WJ, Neuringer IP, Park RC, Sterka DG, Long BR, McNeillie P, Noelle RJ, Ting JP, Aris RM. Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance. Thorax. 61: 61-7. PMID 16254057 DOI: 10.1136/thx.2005.047316  0.223
2022 Watkins-Schulz R, Batty CJ, Stiepel RT, Schmidt ME, Sandor AM, Chou WC, Ainslie KM, Bachelder EM, Ting JP. Microparticle Delivery of a STING Agonist Enables Indirect Activation of NK Cells by Antigen-Presenting Cells. Molecular Pharmaceutics. PMID 35913984 DOI: 10.1021/acs.molpharmaceut.2c00207  0.222
2019 Mauck MC, Linnstaedt SD, Bortsov A, Kurz M, Hendry PL, Lewandowski C, Velilla MA, Datner E, Pearson C, Domeier R, Fillingim RB, Beaudoin FL, Ting JP, McLean SA. Vitamin D insufficiency increases risk of chronic pain among African Americans experiencing motor vehicle collision. Pain. PMID 31651575 DOI: 10.1097/J.Pain.0000000000001728  0.221
1997 Ting JP, Wright KL, Chin KC, Brickey WJ, Li G. The DMB promoter: delineation, in vivo footprint, trans-activation, and trans-dominant suppression. Journal of Immunology (Baltimore, Md. : 1950). 159: 5457-62. PMID 9548486  0.219
2015 Guo H, Callaway JB, Ting JP. Inflammasomes: mechanism of action, role in disease, and therapeutics. Nature Medicine. 21: 677-87. PMID 26121197 DOI: 10.1038/nm.3893  0.219
1997 Chin KC, Li G, Ting JP. Activation and transdominant suppression of MHC class II and HLA-DMB promoters by a series of C-terminal class II transactivator deletion mutants. Journal of Immunology (Baltimore, Md. : 1950). 159: 2789-94. PMID 9300700  0.218
2000 Taxman DJ, Cressman DE, Ting JP. Identification of class II transcriptional activator-induced genes by representational difference analysis: discoordinate regulation of the DN alpha/DO beta heterodimer. Journal of Immunology (Baltimore, Md. : 1950). 165: 1410-6. PMID 10903745 DOI: 10.4049/jimmunol.165.3.1410  0.218
2022 Swanson KV, Girnary M, Alves T, Ting JP, Divaris K, Beck J, Pucinelli CM, da Silva RAB, Uyan D, Wilson J, Seaman WT, Webster-Cyriaque J, Vias N, Jiao Y, Cantley L, et al. Interferon activated gene 204 (Ifi204) protects against bone loss in experimental periodontitis. Journal of Periodontology. PMID 35404474 DOI: 10.1002/JPER.21-0668  0.218
1999 Harton JA, Cressman DE, Chin KC, Der CJ, Ting JP. GTP binding by class II transactivator: role in nuclear import. Science (New York, N.Y.). 285: 1402-5. PMID 10464099 DOI: 10.1126/Science.285.5432.1402  0.217
1987 Yokota S, Yuan D, Katagiri T, Eisenberg RA, Cohen PL, Ting JP. The expression and regulation of c-myb transcription in B6/lpr Lyt-2-, L3T4-T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 139: 2810-7. PMID 3116095  0.216
2006 Kurtz S, McKinnon KP, Runge MS, Ting JP, Braunstein M. The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response. Infection and Immunity. 74: 6855-64. PMID 17030572 DOI: 10.1128/Iai.01022-06  0.215
1992 Moses H, Panek RB, Benveniste EN, Ting JP. Usage of primary cells to delineate IFN-gamma-responsive DNA elements in the HLA-DRA promoter and to identify a novel IFN-gamma-enhanced nuclear factor. Journal of Immunology (Baltimore, Md. : 1950). 148: 3643-51. PMID 1588050  0.215
2002 Ting JP, Trowsdale J. Genetic control of MHC class II expression. Cell. 109: S21-33. PMID 11983150 DOI: 10.1016/S0092-8674(02)00696-7  0.214
2015 Roberts RA, Eitas TK, Byrne JD, Johnson BM, Short PJ, McKinnon KP, Reisdorf S, Luft JC, DeSimone JM, Ting JP. Towards programming immune tolerance through geometric manipulation of phosphatidylserine. Biomaterials. 72: 1-10. PMID 26325217 DOI: 10.1016/J.Biomaterials.2015.08.040  0.214
2015 Liu R, Truax AD, Chen L, Hu P, Li Z, Chen J, Song C, Chen L, Ting JP. Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components. Oncotarget. PMID 26378020 DOI: 10.18632/oncotarget.5587  0.214
2006 Hoffman BG, Williams KL, Tien AH, Lu V, de Algara TR, Ting JP, Helgason CD. Identification of novel genes and transcription factors involved in spleen, thymus and immunological development and function. Genes and Immunity. 7: 101-12. PMID 16355110 DOI: 10.1038/Sj.Gene.6364270  0.213
1988 Katagiri K, Katagiri T, Yokota S, Eisenberg RA, Cohen PL, Ting JP. Two different molecular pathways account for low IL-2 receptor and c-myc mRNA expression by lpr Lyt-2- L3T4- T cells. Journal of Immunology (Baltimore, Md. : 1950). 141: 2145-52. PMID 3139753  0.213
2008 McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, Ting JP, Marriott I. Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 30-40. PMID 17907925 DOI: 10.1359/Jbmr.071002  0.211
1988 Basta PV, Sherman PA, Ting JP. Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line. Proceedings of the National Academy of Sciences of the United States of America. 85: 8618-22. PMID 2847168 DOI: 10.1073/PNAS.85.22.8618  0.211
1987 Sherman PA, Basta PV, Ting JP. Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 4254-8. PMID 3495805 DOI: 10.1073/PNAS.84.12.4254  0.21
2015 Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE, de Silva AM, Ting JP. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model. Plos One. 10: e0136708. PMID 26301593 DOI: 10.1371/journal.pone.0136708  0.209
2021 Chou WC, Rampanelli E, Li X, Ting JP. Impact of intracellular innate immune receptors on immunometabolism. Cellular & Molecular Immunology. PMID 34697412 DOI: 10.1038/s41423-021-00780-y  0.209
2002 Tompkins SM, Padilla J, Dal Canto MC, Ting JP, Van Kaer L, Miller SD. De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 168: 4173-83. PMID 11937578  0.208
1997 Katula KS, Wright KL, Paul H, Surman DR, Nuckolls FJ, Smith JW, Ting JP, Yates J, Cogswell JP. Cyclin-dependent kinase activation and S-phase induction of the cyclin B1 gene are linked through the CCAAT elements. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 8: 811-20. PMID 9218875  0.208
1993 Cogswell JP, Cogswell PC, Kuehl WM, Cuddihy AM, Bender TM, Engelke U, Marcu KB, Ting JP. Mechanism of c-myc regulation by c-Myb in different cell lineages. Molecular and Cellular Biology. 13: 2858-69. PMID 8474446 DOI: 10.1128/mcb.13.5.2858-2869.1993  0.207
1991 Moses H, Sasaki A, Ting JP. Identification of an interferon-gamma-responsive element of a class II major histocompatibility gene in rat type 1 astrocytes. Journal of Neuroimmunology. 31: 273-8. PMID 1899871 DOI: 10.1016/0165-5728(91)90049-D  0.205
2007 Botten J, Whitton JL, Barrowman P, Sidney J, Whitmire JK, Alexander J, Ting JP, Bui HH, Sette A, Buchmeier MJ. HLA-A2-restricted protection against lethal lymphocytic choriomeningitis. Journal of Virology. 81: 2307-17. PMID 17166907 DOI: 10.1128/Jvi.02063-06  0.205
2013 Wen H, Miao EA, Ting JP. Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity. 39: 432-41. PMID 24054327 DOI: 10.1016/j.immuni.2013.08.037  0.204
2005 Johnnidis JB, Venanzi ES, Taxman DJ, Ting JP, Benoist CO, Mathis DJ. Chromosomal clustering of genes controlled by the aire transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 102: 7233-8. PMID 15883360 DOI: 10.1073/Pnas.0502670102  0.202
2013 Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C. Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. Embo Reports. 14: 900-6. PMID 24008845 DOI: 10.1038/Embor.2013.132  0.201
2010 Taylor LC, Puranam K, Gilmore W, Ting JP, Matsushima GK. 17beta-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss. Neurobiology of Disease. 39: 127-37. PMID 20347981 DOI: 10.1016/J.Nbd.2010.03.016  0.2
2008 Attia RR, Gardner LA, Mahrous E, Taxman DJ, Legros L, Rowe S, Ting JP, Geller A, Kotb M. Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis. The Journal of Biological Chemistry. 283: 30788-95. PMID 18753136 DOI: 10.1074/jbc.M804159200  0.2
1997 Martin BK, Chin KC, Olsen JC, Skinner CA, Dey A, Ozato K, Ting JP. Induction of MHC class I expression by the MHC class II transactivator CIITA. Immunity. 6: 591-600. PMID 9175837 DOI: 10.1016/S1074-7613(00)80347-7  0.2
2020 Lin L, Hwang BJ, Li N, Googe P, Diaz LA, Miao E, Vilen B, Thomas NE, Ting J, Liu Z. Non-Cell-Autonomous Activity of the Hemidesmosomal Protein BP180/Collagen XVII in Granulopoiesis in Humanized NC16A Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32998984 DOI: 10.4049/jimmunol.2000784  0.198
2007 Lich JD, Ting JP. Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions. Microbes and Infection / Institut Pasteur. 9: 672-6. PMID 17418609 DOI: 10.1016/J.Micinf.2007.01.018  0.198
2014 Fang L, Gong J, Wang Y, Liu R, Li Z, Wang Z, Zhang Y, Zhang C, Song C, Yang A, Ting JP, Jin B, Chen L. MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 33: 76. PMID 25228093 DOI: 10.1186/S13046-014-0076-7  0.197
1994 Chen X, Wright KL, Berkowitz EA, Azizkhan JC, Ting JP, Lee DC. Protein interactions at Sp1-like sites in the TGF alpha promoter as visualized by in vivo genomic footprinting. Oncogene. 9: 3179-87. PMID 7936640  0.196
2006 Wright KL, Ting JP. Epigenetic regulation of MHC-II and CIITA genes. Trends in Immunology. 27: 405-12. PMID 16870508 DOI: 10.1016/j.it.2006.07.007  0.196
2002 June Brickey W, Felix NJ, Griffiths R, Zhang J, Wang B, Piskurich JF, Itoh-Lindstrom Y, Coffman TM, Ting JP. Prolonged survival of class II transactivator-deficient cardiac allografts. Transplantation. 74: 1341-8. PMID 12451276 DOI: 10.1097/00007890-200211150-00024  0.195
2014 Guo H, Gao J, Taxman DJ, Ting JP, Su L. HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes. The Journal of Biological Chemistry. 289: 21716-26. PMID 24939850 DOI: 10.1074/Jbc.M114.566620  0.195
2016 Shao WH, Shu DH, Zhen Y, Hilliard B, Priest SO, Cesaroni M, Ting JP, Cohen PL. Prion-like MAVS aggregation in lupus patients associates with increased interferon-I. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27110677 DOI: 10.1002/Art.39733  0.194
1991 Brown AM, Barr CL, Ting JP. Sequences homologous to class II MHC W, X, and Y elements mediate constitutive and IFN-gamma-induced expression of human class II-associated invariant chain gene. Journal of Immunology (Baltimore, Md. : 1950). 146: 3183-9. PMID 1901895  0.193
1989 Basta PV, Moore TL, Yokota S, Ting JP. A beta-adrenergic agonist modulates DR alpha gene transcription via enhanced cAMP levels in a glioblastoma multiforme line. Journal of Immunology (Baltimore, Md. : 1950). 142: 2895-901. PMID 2467944  0.193
1995 MacDonald GH, Itoh-Lindstrom Y, Ting JP. The transcriptional regulatory protein, YB-1, promotes single-stranded regions in the DRA promoter. The Journal of Biological Chemistry. 270: 3527-33. PMID 7876087 DOI: 10.1074/JBC.270.8.3527  0.192
2007 Lich JD, Ting JP. CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses. Proceedings of the American Thoracic Society. 4: 263-6. PMID 17607010 DOI: 10.1513/pats.200701-022AW  0.192
1990 Cogswell JP, Basta PV, Ting JP. X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements. Proceedings of the National Academy of Sciences of the United States of America. 87: 7703-7. PMID 2120707 DOI: 10.1073/PNAS.87.19.7703  0.191
2021 Cheng L, Li G, Pellegry CM, Yasui F, Li F, Zurawski SM, Zurawski G, Levy Y, Ting JP, Su L. TLR9- and CD40-Targeting Vaccination Promotes Human B Cell Maturation and IgG Induction pDC-Dependent Mechanisms in Humanized Mice. Frontiers in Immunology. 12: 672143. PMID 34093572 DOI: 10.3389/fimmu.2021.672143  0.19
1999 Martin BK, Frelinger JG, Ting JP. Combination gene therapy with CD86 and the MHC class II transactivator in the control of lung tumor growth. Journal of Immunology (Baltimore, Md. : 1950). 162: 6663-70. PMID 10352284  0.19
2000 Saifuddin M, Roebuck KA, Chang Ch, Ting JP, Spear GT. Cutting edge: activation of HIV-1 transcription by the MHC class II transactivator. Journal of Immunology (Baltimore, Md. : 1950). 164: 3941-5. PMID 10754282 DOI: 10.4049/Jimmunol.164.8.3941  0.189
2007 Shabman RS, Morrison TE, Moore C, White L, Suthar MS, Hueston L, Rulli N, Lidbury B, Ting JP, Mahalingam S, Heise MT. Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses. Journal of Virology. 81: 237-47. PMID 17079324 DOI: 10.1128/Jvi.01590-06  0.189
1987 Evans JL, Boyle WJ, Ting JP. Molecular basis of elevated c-myb expression in the abnormal L3T4-, Lyt-2- T lymphocytes of autoimmune mice. Journal of Immunology (Baltimore, Md. : 1950). 139: 3497-505. PMID 3316384  0.189
1999 Cressman DE, Chin KC, Taxman DJ, Ting JP. A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome. Immunity. 10: 163-71. PMID 10072069 DOI: 10.1016/S1074-7613(00)80017-5  0.186
2008 Moore CB, Ting JP. Regulation of mitochondrial antiviral signaling pathways. Immunity. 28: 735-9. PMID 18549796 DOI: 10.1016/j.immuni.2008.05.005  0.184
1995 Itoh-Lindstrom Y, Peterlin BM, Ting JP. Affinity enrichment and functional characterization of TRAX1, a novel transcription activator and X1-sequence-binding protein of HLA-DRA. Molecular and Cellular Biology. 15: 282-9. PMID 7799935 DOI: 10.1128/MCB.15.1.282  0.183
2013 Mendoza A, Linz B, Kartchner L, Brickey W, Ting J, Cairns B, Maile R. Distinct Immature Myeloid Populations Arise After Radiation Combined With Thermal Injury Journal of Surgical Research. 179: 327-328. DOI: 10.1016/J.Jss.2012.10.663  0.183
2015 Ting JP, Harton JA. NLRP3 moonlights in TH2 polarization. Nature Immunology. 16: 794-6. PMID 26194278 DOI: 10.1038/Ni.3223  0.18
1992 Vilen BJ, Penta JF, Ting JP. Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-gamma-inducible expression of the HLA-DRA gene. The Journal of Biological Chemistry. 267: 23728-34. PMID 1331098  0.179
1991 Vilen BJ, Cogswell JP, Ting JP. Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function. Molecular and Cellular Biology. 11: 2406-15. PMID 1901941 DOI: 10.1128/mcb.11.5.2406-2415.1991  0.176
2018 Cheng N, Watkins-Schulz R, Junkins RD, David CN, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, ... Ting JP, et al. A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer. Jci Insight. 3. PMID 30429378 DOI: 10.1172/Jci.Insight.120638  0.175
1987 Carrington MN, Chedid M, Ting JP, Ward FE. Differential expression of the HLA-DR genes in various melanoma cell lines treated with interferon-gamma: methylation of the HLA-DR alpha gene in these lines is not correlated with its expression. Human Immunology. 18: 151-61. PMID 3104241 DOI: 10.1016/0198-8859(87)90012-7  0.174
2022 Sun L, Feng H, Misumi I, Shirasaki T, Hensley L, González-López O, Shiota I, Chou WC, Ting JP, Cullen JM, Cowley DO, Whitmire JK, Lemon SM. Viral protease cleavage of MAVS in genetically modified mice with hepatitis A virus infection. Journal of Hepatology. PMID 36152761 DOI: 10.1016/j.jhep.2022.09.013  0.174
1997 Armstrong TD, Clements VK, Martin BK, Ting JP, Ostrand-Rosenberg S. Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity. Proceedings of the National Academy of Sciences of the United States of America. 94: 6886-91. PMID 9192661 DOI: 10.1073/Pnas.94.13.6886  0.173
1994 Wright KL, Vilen BJ, Itoh-Lindstrom Y, Moore TL, Li G, Criscitiello M, Cogswell P, Clarke JB, Ting JP. CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors. The Embo Journal. 13: 4042-53. PMID 8076600  0.172
2020 Barnett KC, Ting JP. Mitochondrial GSDMD Pores DAMPen Pyroptosis. Immunity. 52: 424-426. PMID 32187511 DOI: 10.1016/j.immuni.2020.02.012  0.171
2020 Perry JL, Tian S, Sengottuvel N, Harrison EB, Gorentla BK, Kapadia CH, Cheng N, Luft JC, Ting JP, DeSimone JM, Pecot CV. Pulmonary Delivery of Nanoparticle-Bound Toll-Like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer. Acs Nano. PMID 32463690 DOI: 10.1021/Acsnano.0C02207  0.17
2007 Moore CB, Medina MA, van Deventer HW, O'Connor BP, Cameron S, Taxman DJ, Maile R, Ting JP, Cairns BA. Downregulation of immune signaling genes in patients with large surface burn injury. Journal of Burn Care & Research : Official Publication of the American Burn Association. 28: 879-87. PMID 17925653 DOI: 10.1097/Bcr.0B013E318159A41E  0.167
2007 Burrer R, Buchmeier MJ, Wolfe T, Ting JP, Feuer R, Iglesias A, von Herrath MG. Exacerbated pathology of viral encephalitis in mice with central nervous system-specific autoantibodies. The American Journal of Pathology. 170: 557-66. PMID 17255324 DOI: 10.2353/Ajpath.2007.060893  0.167
1989 Sasaki A, Levison SW, Ting JP. Comparison and quantitation of Ia antigen expression on cultured macroglia and ameboid microglia from Lewis rat cerebral cortex: analyses and implications. Journal of Neuroimmunology. 25: 63-74. PMID 2584392 DOI: 10.1016/0165-5728(89)90087-8  0.165
2012 Mendoza AE, Neely CJ, Charles AG, Kartchner LB, Brickey WJ, Khoury AL, Sempowski GD, Ting JP, Cairns BA, Maile R. Radiation combined with thermal injury induces immature myeloid cells. Shock (Augusta, Ga.). 38: 532-42. PMID 23042190 DOI: 10.1097/Shk.0B013E31826C5B19  0.164
2023 Hu X, Wong SW, Liang K, Wu TH, Wang S, Wang L, Liu J, Yamauchi M, Foster BL, Ting JP, Zhao B, Tseng HC, Ko CC. Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget's disease of bone. Science Advances. 9: eade6998. PMID 36706179 DOI: 10.1126/sciadv.ade6998  0.156
1985 Ting JP, Carrington MN, Salter RD, DeMars R, Cresswell P. Evidence for chromatin structure as a regulatory determinant in HLA-DR alpha gene expression. Immunogenetics. 22: 571-83. PMID 3000934 DOI: 10.1007/Bf00430305  0.154
2023 Cox AD, Ting JP, Der CJ. Convergence of Targeted and Immune Therapies for the Treatment of Oncogene-Driven Cancers. Cancer Discovery. 13: 19-22. PMID 36620884 DOI: 10.1158/2159-8290.CD-22-1199  0.154
2011 Brickey WJ, Alexis NE, Hernandez ML, Reed W, Ting JP, Peden DB. Sputum inflammatory cells from patients with allergic rhinitis and asthma have decreased inflammasome gene expression. The Journal of Allergy and Clinical Immunology. 128: 900-3. PMID 21868073 DOI: 10.1016/j.jaci.2011.08.012  0.146
2007 Burrer R, Neuman BW, Ting JP, Stein DA, Moulton HM, Iversen PL, Kuhn P, Buchmeier MJ. Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models. Journal of Virology. 81: 5637-48. PMID 17344287 DOI: 10.1128/Jvi.02360-06  0.146
2022 Diamond MS, Lambris JD, Ting JP, Tsang JS. Considering innate immune responses in SARS-CoV-2 infection and COVID-19. Nature Reviews. Immunology. PMID 35788185 DOI: 10.1038/s41577-022-00744-x  0.146
2017 Kurkjian CJ, Guo H, Montgomery ND, Cheng N, Yuan H, Merrill JR, Sempowski GD, Brickey WJ, Ting JP. The Toll-Like Receptor 2/6 Agonist, FSL-1 Lipopeptide, Therapeutically Mitigates Acute Radiation Syndrome. Scientific Reports. 7: 17355. PMID 29230065 DOI: 10.1038/s41598-017-17729-9  0.145
2007 Saunders AA, Ting JP, Meisner J, Neuman BW, Perez M, de la Torre JC, Buchmeier MJ. Mapping the landscape of the lymphocytic choriomeningitis virus stable signal peptide reveals novel functional domains. Journal of Virology. 81: 5649-57. PMID 17376927 DOI: 10.1128/Jvi.02759-06  0.144
2000 Felix NJ, Brickey WJ, Griffiths R, Zhang J, Van Kaer L, Coffman T, Ting JP. H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection. The Journal of Experimental Medicine. 192: 31-40. PMID 10880524 DOI: 10.1084/jem.192.1.31  0.144
2012 Xiao TS, Ting JP. NLRX1 has a tail to tell. Immunity. 36: 311-2. PMID 22444625 DOI: 10.1016/j.immuni.2012.03.002  0.143
2013 Jones SW, Roberts RA, Robbins GR, Perry JL, Kai MP, Chen K, Bo T, Napier ME, Ting JP, Desimone JM, Bear JE. Nanoparticle clearance is governed by Th1/Th2 immunity and strain background. The Journal of Clinical Investigation. 123: 3061-73. PMID 23778144 DOI: 10.1172/Jci66895  0.143
2014 Robbins GR, Wen H, Ting JP. Inflammasomes and metabolic disorders: old genes in modern diseases. Molecular Cell. 54: 297-308. PMID 24766894 DOI: 10.1016/j.molcel.2014.03.029  0.143
1985 Carrington MN, Salter RD, Cresswell P, Ting JP. Evidence for methylation as a regulatory mechanism in HLA-DR alpha gene expression. Immunogenetics. 22: 219-29. PMID 2995246 DOI: 10.1007/BF00404481  0.143
2015 Robbins GR, Roberts RA, Guo H, Reuter K, Shen T, Sempowski GD, McKinnon KP, Su L, DeSimone JM, Ting JP. Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 589-99. PMID 25596079 DOI: 10.1016/J.Nano.2014.11.010  0.142
2015 Fromen CA, Robbins GR, Shen TW, Kai MP, Ting JP, DeSimone JM. Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization. Proceedings of the National Academy of Sciences of the United States of America. 112: 488-93. PMID 25548169 DOI: 10.1073/Pnas.1422923112  0.141
1993 Matsushima GK, Itoh-Lindstrom Y, Ting JP. Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements. Molecular and Cellular Biology. 13: 5132. PMID 8336739 DOI: 10.1128/mcb.13.8.5132-.1993  0.14
2013 Roberts RA, Shen T, Allen IC, Hasan W, DeSimone JM, Ting JP. Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles. Plos One. 8: e62115. PMID 23593509 DOI: 10.1371/Journal.Pone.0062115  0.139
2008 Kim D, Hoory T, Monie A, Ting JP, Hung CF, Wu TC. Enhancement of DNA vaccine potency through coadministration of CIITA DNA with DNA vaccines via gene gun. Journal of Immunology (Baltimore, Md. : 1950). 180: 7019-27. PMID 18453624 DOI: 10.4049/JIMMUNOL.180.10.7019  0.138
1989 Katagiri T, Ting JP, Dy R, Prokop C, Cohen P, Earp HS. Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr mice. Molecular and Cellular Biology. 9: 4914-22. PMID 2557544 DOI: 10.1128/mcb.9.11.4914-4922.1989  0.138
2016 Hirai-Yuki A, Hensley L, McGivern DR, González-López O, Das A, Feng H, Sun L, Wilson JE, Hu F, Feng Z, Lovell W, Misumi I, Ting JP, Montgomery S, Cullen J, et al. MAVS-dependent host species range and pathogenicity of human hepatitis A virus. Science (New York, N.Y.). PMID 27633528 DOI: 10.1126/Science.Aaf8325  0.138
2008 Alexis NE, Brickey WJ, Lay JC, Wang Y, Roubey RA, Ting JP, Peden DB. Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 100: 206-15. PMID 18426139 DOI: 10.1016/S1081-1206(10)60444-9  0.137
1984 Howell DN, Kostyu DD, Ting JP, Cresswell P. Expression of class I histocompatibility antigens on human T-B lymphoblast hybrids. Somatic Cell and Molecular Genetics. 10: 217-24. PMID 6609440 DOI: 10.1007/BF01535244  0.137
2018 Truax AD, Chen L, Tam JW, Cheng N, Guo H, Koblansky AA, Chou WC, Wilson JE, Brickey WJ, Petrucelli A, Liu R, Cooper DE, Koenigsknecht MJ, Young VB, Netea MG, ... ... Ting JP, et al. The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis. Cell Host & Microbe. 24: 364-378.e6. PMID 30212649 DOI: 10.1016/J.Chom.2018.08.009  0.137
2022 Ting JP. The All-Encompassing Importance of Innate Immunity. Journal of Immunology (Baltimore, Md. : 1950). 208: 2445-2449. PMID 35595304 DOI: 10.4049/jimmunol.2290008  0.136
2010 Taylor LC, Gilmore W, Ting JP, Matsushima GK. Cuprizone induces similar demyelination in male and female C57BL/6 mice and results in disruption of the estrous cycle. Journal of Neuroscience Research. 88: 391-402. PMID 19746424 DOI: 10.1002/Jnr.22215  0.131
2022 Whitson HE, Colton C, El Khoury J, Gate D, Goate A, Heneka MT, Kaddurah-Daouk R, Klein RS, Shinohara ML, Sisodia S, Spudich SS, Stevens B, Tanzi R, Ting JP, Garden G. Infection and inflammation: New perspectives on Alzheimer's disease. Brain, Behavior, & Immunity - Health. 22: 100462. PMID 36118272 DOI: 10.1016/j.bbih.2022.100462  0.126
2021 Guo H, Wang Q, Ghneim K, Wang L, Rampanelli E, Holley-Guthrie E, Cheng L, Garrido C, Margolis DM, Eller LA, Robb ML, Sekaly RP, Chen X, Su L, Ting JP. Multi-omics analyses reveal that HIV-1 alters CD4 T cell immunometabolism to fuel virus replication. Nature Immunology. PMID 33767427 DOI: 10.1038/s41590-021-00898-1  0.125
2020 Moecking J, Laohamonthonkul P, Chalker K, White MJ, Harapas CR, Yu CH, Davidson S, Schaale KH, Hu D, Eng C, Huntsman S, Calleja DJ, Horvat JC, Hansbro PM, O'Donoghue RJJ, ... Ting JP, et al. NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity. The Journal of Allergy and Clinical Immunology. PMID 33378691 DOI: 10.1016/j.jaci.2020.12.636  0.124
1992 Gaur LK, Heise ER, Ting JP. Conservation of the promoter region of DRA-like genes from nonhuman primates. Immunogenetics. 35: 136-9. PMID 1735559 DOI: 10.1007/BF00189524  0.123
2012 Hernandez ML, Herbst M, Lay JC, Alexis NE, Brickey WJ, Ting JP, Zhou H, Peden DB. Atopic asthmatic patients have reduced airway inflammatory cell recruitment after inhaled endotoxin challenge compared with healthy volunteers. The Journal of Allergy and Clinical Immunology. 130: 869-76.e2. PMID 22770265 DOI: 10.1016/J.Jaci.2012.05.026  0.121
2002 Felix NJ, de Serres S, Meyer AA, Ting JP. Comparison of Abeta(b-/-), H2-DM(-), and CIITA(-/-) in second-set skin allograft rejection. The Journal of Surgical Research. 102: 185-92. PMID 11796017 DOI: 10.1006/jsre.2001.6311  0.12
2024 Pena ES, Batty CJ, Hendy DA, Yang S, Ontiveros-Padilla L, Stiepel RT, Ting JP, Ainslie KM, Bachelder EM. Comparative study of acetalated-dextran microparticle fabrication methods for a clinically translatable subunit-based influenza vaccine. International Journal of Pharmaceutics. 652: 123836. PMID 38266940 DOI: 10.1016/j.ijpharm.2024.123836  0.118
2015 Kai MP, Brighton HE, Fromen CA, Shen TW, Luft JC, Luft YE, Keeler AW, Robbins GR, Ting JP, Zamboni WC, Bear JE, DeSimone JM. Tumor Presence Induces Global Immune Changes and Enhances Nanoparticle Clearance. Acs Nano. PMID 26592524 DOI: 10.1021/Acsnano.5B05999  0.117
1993 Ting JP. Current concepts in DRA gene regulation. Immunologic Research. 12: 65-77. PMID 8515184 DOI: 10.1007/BF02918369  0.116
2021 Chou WC, Guo Z, Guo H, Chen L, Zhang G, Liang K, Xie L, Tan X, Gibson SA, Rampanelli E, Wang Y, Montgomery SA, Brickey WJ, Deng M, Freeman L, ... ... Ting JP, et al. Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases. Nature. PMID 33854241 DOI: 10.1038/s41586-021-03490-7  0.114
2017 Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. Erratum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nature Immunology. 18: 951. PMID 28722719 DOI: 10.1038/ni0817-951e  0.11
1980 Ting JP, Ranney DF. Selective suppression of the murine autologous mixed lymphocyte reaction by physiological concentrations of hydrocortisone: effects on cell-surface Ia antigens. Cellular Immunology. 53: 138-50. PMID 6447544 DOI: 10.1016/0008-8749(80)90433-5  0.107
2017 Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. Corrigendum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nature Immunology. 18: 1270. PMID 29044233 DOI: 10.1038/ni1117-1270b  0.103
2012 Hernandez M, Brickey WJ, Alexis NE, Fry RC, Rager JE, Zhou B, Ting JP, Zhou H, Peden DB. Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile. The Journal of Allergy and Clinical Immunology. 129: 259-61.e1-2. PMID 22196529 DOI: 10.1016/J.Jaci.2011.11.007  0.103
2011 Neuman BW, Bederka LH, Stein DA, Ting JP, Moulton HM, Buchmeier MJ. Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. Antimicrobial Agents and Chemotherapy. 55: 4631-8. PMID 21825302 DOI: 10.1128/Aac.00650-11  0.101
2022 Awoniyi M, Wang J, Ngo B, Meadows V, Tam J, Viswanathan A, Lai Y, Montgomery S, Farmer M, Kummen M, Thingholm L, Schramm C, Bang C, Franke A, Lu K, ... ... Ting J, et al. Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC. Gut. PMID 35705368 DOI: 10.1136/gutjnl-2021-326500  0.099
2001 Taxman DJ, Ting JP. Identification of novel Mycoplasma hyorhinis gene fragments by differential display analysis of co-cultures. Journal of Microbiological Methods. 44: 217-23. PMID 11240044 DOI: 10.1016/S0167-7012(01)00215-9  0.097
2008 Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, Mackenzie A, Maltais LJ, et al. The NLR gene family: a standard nomenclature. Immunity. 28: 285-7. PMID 18341998 DOI: 10.1016/J.Immuni.2008.02.005  0.095
2022 Cai D, Brickey WJ, Ting JP, Sad S. Correction: Isolates of Salmonella typhimurium circumvent NLRP3 inflammasome recognition in macrophages during the chronic phase of infection. The Journal of Biological Chemistry. 298: 101877. PMID 35378362 DOI: 10.1016/j.jbc.2022.101877  0.094
1984 Tajima S, Ting JP, Pinnell SR, Kaufman RE. Isolation and characterization of a human pro alpha 2(I) collagen gene segment. The Journal of Investigative Dermatology. 82: 265-9. PMID 6321602 DOI: 10.1111/1523-1747.EP12260213  0.082
2018 Johnson BM, Junkins RD, Ting JP. A spike in inflammation. Nature Nanotechnology. PMID 30374158 DOI: 10.1038/s41565-018-0292-y  0.082
2016 Swanson KV, Ting JP. Reining in uncontrolled inflammasome with PKA. Nature Immunology. 17: 1137-1138. PMID 27648539 DOI: 10.1038/ni.3556  0.081
2018 Chen N, Gallovic MD, Tiet P, Ting JP, Ainslie KM, Bachelder EM. Investigation of tunable acetalated dextran microparticle platform to optimize M2e-based influenza vaccine efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30261204 DOI: 10.1016/J.Jconrel.2018.09.020  0.079
2018 Chung WC, Kang HR, Yoon H, Kang SJ, Ting JP, Song MJ. Correction: Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome. Plos One. 13: e0200624. PMID 29990347 DOI: 10.1371/journal.pone.0200624  0.066
1998 Godbold GD, Ahn K, Yeyeodu S, Lee LF, Ting JP, Erickson AH. Biosynthesis and intracellular targeting of the lysosomal aspartic proteinase cathepsin D. Advances in Experimental Medicine and Biology. 436: 153-62. PMID 9561213 DOI: 10.1007/978-1-4615-5373-1_21  0.061
2021 Barnett KC, Liang K, Ting JP. Move over NAIP, DDX17 diversifies the NLRC4 inflammasome. Science Immunology. 6: eabm1201. PMID 34860580 DOI: 10.1126/sciimmunol.abm1201  0.056
2010 Davis BK, Ting JP. NLRP3 has a sweet tooth. Nature Immunology. 11: 105-6. PMID 20084064 DOI: 10.1038/ni0210-105  0.055
2022 Gallovic MD, Junkins RD, Sandor AM, Pena ES, Sample CJ, Mason AK, Arwood LC, Sahm RA, Bachelder EM, Ainslie KM, Sempowski GD, Ting JP. STING agonist-containing microparticles improve seasonal influenza vaccine efficacy and durability in ferrets over standard adjuvant. Journal of Controlled Release : Official Journal of the Controlled Release Society. 347: 356-368. PMID 35569585 DOI: 10.1016/j.jconrel.2022.05.017  0.053
2021 Ting J. A Conversation with Dr. Jenny Ting. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 41: 363-364. PMID 34672800 DOI: 10.1089/jir.2021.29028.exp  0.05
2015 Kang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, Homer R, Dhamija A, Boffa D, West AP, Shadel GS, Ting JP, Tedrow JR, Kaminski N, Kim WJ, et al. Suppression of NLRX1 in chronic obstructive pulmonary disease Journal of Clinical Investigation. 125: 2458-2462. DOI: 10.1172/JCI71747  0.045
2006 Ting JP, Kastner DL, Hoffman HM. CATERPILLERs, pyrin and hereditary immunological disorders. Nature Reviews. Immunology. 6: 183-95. PMID 16498449 DOI: 10.1038/nri1788  0.026
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