Year |
Citation |
Score |
2015 |
Fritz JM, Tennis MA, Orlicky DJ, Yin H, Ju C, Redente EF, Choo KS, Staab TA, Bouchard RJ, Merrick DT, Malkinson AM, Dwyer-Nield LD. Corrigendum: depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas. Frontiers in Immunology. 6: 88. PMID 25784911 DOI: 10.3389/Fimmu.2015.00088 |
0.828 |
|
2014 |
Fritz JM, Tennis MA, Orlicky DJ, Lin H, Ju C, Redente EF, Choo KS, Staab TA, Bouchard RJ, Merrick DT, Malkinson AM, Dwyer-Nield LD. Depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas. Frontiers in Immunology. 5: 587. PMID 25505466 DOI: 10.3389/Fimmu.2014.00587 |
0.859 |
|
2013 |
Fritz J, Tennis MA, Malkinson A, Dwyer-Nield L. Abstract 1530: Alveolar macrophage depletion decreases lung cytokines and decreases mouse lung tumor growth. Cancer Research. 73: 1530-1530. DOI: 10.1158/1538-7445.Am2013-1530 |
0.854 |
|
2012 |
Tyagi A, Agarwal C, Dwyer-Nield LD, Singh RP, Malkinson AM, Agarwal R. Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells. Molecular Carcinogenesis. 51: 832-42. PMID 21882257 DOI: 10.1002/Mc.20851 |
0.509 |
|
2012 |
Zhang YQ, Bianco A, Malkinson AM, Leoni VP, Frau G, De Rosa N, André PA, Versace R, Boulvain M, Laurent GJ, Atzori L, Irminger-Finger I. BARD1: an independent predictor of survival in non-small cell lung cancer. International Journal of Cancer. Journal International Du Cancer. 131: 83-94. PMID 21815143 DOI: 10.1002/Ijc.26346 |
0.527 |
|
2011 |
Fritz JM, Dwyer-Nield LD, Malkinson AM. Stimulation of neoplastic mouse lung cell proliferation by alveolar macrophage-derived, insulin-like growth factor-1 can be blocked by inhibiting MEK and PI3K activation. Molecular Cancer. 10: 76. PMID 21699731 DOI: 10.1186/1476-4598-10-76 |
0.831 |
|
2011 |
Ramasamy K, Dwyer-Nield LD, Serkova NJ, Hasebroock KM, Tyagi A, Raina K, Singh RP, Malkinson AM, Agarwal R. Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 753-61. PMID 21148748 DOI: 10.1158/1078-0432.Ccr-10-2290 |
0.533 |
|
2010 |
Rice PL, Barrett BS, Fritz JM, Srebernak MC, Kisley LR, Malkinson AM, Dwyer-Nield LD. Regulation of cytokine-induced prostanoid and nitric oxide synthesis by extracellular signal–regulated kinase 1/2 in lung epithelial cells. Experimental Lung Research. 36: 558-71. PMID 20815659 DOI: 10.3109/01902148.2010.491891 |
0.82 |
|
2010 |
Redente EF, Dwyer-Nield LD, Merrick DT, Raina K, Agarwal R, Pao W, Rice PL, Shroyer KR, Malkinson AM. Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization. The American Journal of Pathology. 176: 2972-85. PMID 20431028 DOI: 10.2353/Ajpath.2010.090879 |
0.781 |
|
2010 |
Redente EF, Higgins DM, Dwyer-Nield LD, Orme IM, Gonzalez-Juarrero M, Malkinson AM. Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation. Journal of Leukocyte Biology. 88: 159-68. PMID 20360403 DOI: 10.1189/Jlb.0609378 |
0.721 |
|
2010 |
Fritz JM, Dwyer-Nield LD, Russell BM, Malkinson AM. The Kras mutational spectra of chemically induced lung tumors in different inbred mice mimics the spectra of KRAS mutations in adenocarcinomas in smokers versus nonsmokers. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 254-7. PMID 20101149 DOI: 10.1097/Jto.0B013E3181C8Ce04 |
0.818 |
|
2010 |
Reynolds SD, Malkinson AM. Clara cell: progenitor for the bronchiolar epithelium. The International Journal of Biochemistry & Cell Biology. 42: 1-4. PMID 19747565 DOI: 10.1016/J.Biocel.2009.09.002 |
0.381 |
|
2010 |
Dwyer-Nield LD, McQuillan J, Hill-Baskin A, Radcliffe RA, You M, Nadeau JH, Malkinson AM. Epistatic interactions govern chemically-induced lung tumor susceptibility and Kras mutation site in murine C57BL/6J-ChrA/J chromosome substitution strains. International Journal of Cancer. 126: 125-32. PMID 19609923 DOI: 10.1002/Ijc.24743 |
0.529 |
|
2010 |
Ramasamy K, Nield LD, Serkova NJ, Hasebroock KM, Tyagi A, Raina K, Malkinson AM, Agarwal R. Abstract 948: Silibinin selectively inhibits growth and progression of urethane-induced lung tumors in wild-type but not inducible nitric oxide synthase (-/-) mice: potential usefulness of micro-computed tomography scanning in lung cancer chemoprevention studies Cancer Research. 70: 948-948. DOI: 10.1158/1538-7445.Am10-948 |
0.623 |
|
2009 |
Redente EF, Dwyer-Nield LD, Barrett BS, Riches DW, Malkinson AM. Lung tumor growth is stimulated in IFN-gamma-/- mice and inhibited in IL-4Ralpha-/- mice. Anticancer Research. 29: 5095-101. PMID 20044622 |
0.757 |
|
2009 |
Tyagi A, Singh RP, Ramasamy K, Raina K, Redente EF, Dwyer-Nield LD, Radcliffe RA, Malkinson AM, Agarwal R. Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3. Cancer Prevention Research (Philadelphia, Pa.). 2: 74-83. PMID 19139021 DOI: 10.1158/1940-6207.Capr-08-0095 |
0.773 |
|
2008 |
Lin S, Ikegami M, Xu Y, Bosserhoff AK, Malkinson AM, Shannon JM. Misexpression of MIA disrupts lung morphogenesis and causes neonatal death. Developmental Biology. 316: 441-55. PMID 18342301 DOI: 10.1016/J.Ydbio.2008.02.003 |
0.547 |
|
2008 |
Stearman RS, Dwyer-Nield L, Grady MC, Malkinson AM, Geraci MW. A macrophage gene expression signature defines a field effect in the lung tumor microenvironment. Cancer Research. 68: 34-43. PMID 18172294 DOI: 10.1158/0008-5472.Can-07-0988 |
0.553 |
|
2008 |
Zerbe LK, Dwyer-Nield LD, Fritz JM, Redente EF, Shroyer RJ, Conklin E, Kane S, Tucker C, Eckhardt SG, Gustafson DL, Iwata KK, Malkinson AM. Inhibition by erlotinib of primary lung adenocarcinoma at an early stage in male mice. Cancer Chemotherapy and Pharmacology. 62: 605-20. PMID 18030469 DOI: 10.1007/S00280-007-0644-Z |
0.835 |
|
2007 |
Peebles KA, Dwyer-Nield LD, Malkinson AM. Altered expression of splicing factor, heterogeneous nuclear ribonucleoprotein A2/B1, in mouse lung neoplasia. Molecular Carcinogenesis. 46: 887-900. PMID 17477362 DOI: 10.1002/Mc.20321 |
0.818 |
|
2007 |
Redente EF, Orlicky DJ, Bouchard RJ, Malkinson AM. Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice. The American Journal of Pathology. 170: 693-708. PMID 17255336 DOI: 10.2353/Ajpath.2007.060566 |
0.806 |
|
2006 |
Keith RL, Geraci MW, Nana-Sinkam SP, Breyer RM, Hudish TM, Meyer AM, Malkinson AM, Dwyer-Nield LD. Prostaglandin E2 receptor subtype 2 (EP2) null mice are protected against murine lung tumorigenesis. Anticancer Research. 26: 2857-61. PMID 16886605 |
0.802 |
|
2006 |
Singh RP, Deep G, Chittezhath M, Kaur M, Dwyer-Nield LD, Malkinson AM, Agarwal R. Effect of silibinin on the growth and progression of primary lung tumors in mice. Journal of the National Cancer Institute. 98: 846-55. PMID 16788158 DOI: 10.1093/Jnci/Djj231 |
0.568 |
|
2006 |
Meyer AM, Dwyer-Nield LD, Hurteau G, Keith RL, Ouyang Y, Freed BM, Kisley LR, Geraci MW, Bonventre JV, Nemenoff RA, Malkinson AM. Attenuation of the pulmonary inflammatory response following butylated hydroxytoluene treatment of cytosolic phospholipase A2 null mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L1260-6. PMID 16443645 DOI: 10.1152/Ajplung.00182.2005 |
0.783 |
|
2006 |
O'Donnell EP, Zerbe LK, Dwyer-Nield LD, Kisley LR, Malkinson AM. Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis. Cancer Letters. 241: 197-202. PMID 16337739 DOI: 10.1016/J.Canlet.2005.10.012 |
0.43 |
|
2006 |
Christiani DC, Pao W, DeMartini JC, Linnoila RI, Malkinson AM, Onn A, Politi KA, Sharp M, Kim K. BAC Consensus Conference, November 4–6, 2004: Epidemiology, Pathogenesis, and Preclinical Models Journal of Thoracic Oncology. 1: S2-S7. DOI: 10.1016/S1556-0864(15)30002-2 |
0.383 |
|
2005 |
Bauer AK, Dixon D, DeGraff LM, Cho HY, Walker CR, Malkinson AM, Kleeberger SR. Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis. Journal of the National Cancer Institute. 97: 1778-81. PMID 16333033 DOI: 10.1093/Jnci/Dji403 |
0.775 |
|
2005 |
Stearman RS, Dwyer-Nield L, Zerbe L, Blaine SA, Chan Z, Bunn PA, Johnson GL, Hirsch FR, Merrick DT, Franklin WA, Baron AE, Keith RL, Nemenoff RA, Malkinson AM, Geraci MW. Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model. The American Journal of Pathology. 167: 1763-75. PMID 16314486 DOI: 10.1016/S0002-9440(10)61257-6 |
0.519 |
|
2005 |
Malkinson AM. Role of inflammation in mouse lung tumorigenesis: a review. Experimental Lung Research. 31: 57-82. PMID 15765919 DOI: 10.1080/01902140490495020 |
0.523 |
|
2005 |
Dwyer-Nield LD, Srebernak MC, Barrett BS, Ahn J, Cosper P, Meyer AM, Kisley LR, Bauer AK, Thompson DC, Malkinson AM. Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines. Carcinogenesis. 26: 1196-206. PMID 15746162 DOI: 10.1093/Carcin/Bgi061 |
0.856 |
|
2004 |
Zerbe LK, Pino I, Pio R, Cosper PF, Dwyer-Nield LD, Meyer AM, Port JD, Montuenga LM, Malkinson AM. Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing. Molecular Carcinogenesis. 41: 187-96. PMID 15390079 DOI: 10.1002/Mc.20053 |
0.786 |
|
2004 |
Bauer AK, Malkinson AM, Kleeberger SR. Susceptibility to neoplastic and non-neoplastic pulmonary diseases in mice: genetic similarities. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L685-703. PMID 15355860 DOI: 10.1152/Ajplung.00223.2003 |
0.773 |
|
2004 |
Lu Y, Bellgrau D, Dwyer-Nield LD, Malkinson AM, Duke RC, Rodell TC, Franzusoff A. Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapy. Cancer Research. 64: 5084-8. PMID 15289309 DOI: 10.1158/0008-5472.Can-04-1487 |
0.433 |
|
2004 |
Malkinson AM. Evidence that inflammation encourages pulmonary adenocarcinoma formation in mice: clinical implications. Chest. 125: 154S-5S. PMID 15136480 DOI: 10.1378/Chest.125.5_Suppl.154S-A |
0.411 |
|
2004 |
Zhang F, Pao W, Umphress S, Jakowlew S, Meyer AM, Dwyer-Nield LD, Takeda K, Gelfand EW, Fisher J, Malkinson AM, Mason RJ. Serum levels of surfactant protein D are increased in mice with lung tumors. Chest. 125: 109S. PMID 15136449 |
0.798 |
|
2004 |
Meyer AM, Dwyer-Nield LD, Hurteau GJ, Keith RL, O'Leary E, You M, Bonventre JV, Nemenoff RA, Malkinson AM. Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2. Carcinogenesis. 25: 1517-24. PMID 15033900 DOI: 10.1093/Carcin/Bgh150 |
0.835 |
|
2004 |
Zhang F, Pao W, Umphress S, Jakowlew S, Meyer A, Dwyer-Nield L, Takeda K, Gelfand E, Fisher J, Malkinson A, Mason RJ. Serum Levels of Surfactant Protein D Are Increased in Mice With Lung Tumors Chest. 125: 109S. DOI: 10.1378/Chest.125.5_Suppl.109S-A |
0.801 |
|
2003 |
Bernert H, Sekikawa K, Radcliffe RA, Iraqi F, You M, Malkinson AM. Tnfa and Il-10 deficiencies have contrasting effects on lung tumor susceptibility: gender-dependent modulation of IL-10 haploinsufficiency. Molecular Carcinogenesis. 38: 117-23. PMID 14587096 DOI: 10.1002/Mc.10151 |
0.509 |
|
2003 |
Zhang F, Pao W, Umphress SM, Jakowlew SB, Meyer AM, Dwyer-Nield LD, Nielsen LD, Takeda K, Gelfand EW, Fisher JH, Zhang L, Malkinson AM, Mason RJ. Serum levels of surfactant protein D are increased in mice with lung tumors. Cancer Research. 63: 5889-94. PMID 14522914 |
0.79 |
|
2003 |
Miller YE, Dwyer-Nield LD, Keith RL, Le M, Franklin WA, Malkinson AM. Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections. Cancer Letters. 198: 139-44. PMID 12957351 DOI: 10.1016/S0304-3835(03)00309-4 |
0.61 |
|
2003 |
Wang M, Lemon WJ, Liu G, Wang Y, Iraqi FA, Malkinson AM, You M. Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Research. 63: 3317-24. PMID 12810665 |
0.319 |
|
2003 |
Peebles KA, Duncan MW, Ruch RJ, Malkinson AM. Proteomic analysis of a neoplastic mouse lung epithelial cell line whose tumorigenicity has been abrogated by transfection with the gap junction structural gene for connexin 43, Gja1. Carcinogenesis. 24: 651-7. PMID 12727792 DOI: 10.1093/Carcin/Bgg008 |
0.791 |
|
2003 |
Sun Y, Dwyer-Nield LD, Malkinson AM, Zhang YL, Thompson JA. Responses of tumorigenic and non-tumorigenic mouse lung epithelial cell lines to electrophilic metabolites of the tumor promoter butylated hydroxytoluene. Chemico-Biological Interactions. 145: 41-51. PMID 12606153 DOI: 10.1016/S0009-2797(02)00161-8 |
0.467 |
|
2003 |
Vultur A, Tomai E, Peebles K, Malkinson AM, Grammatikakis N, Forkert PG, Raptis L. Gap junctional intercellular communication in cells isolated from urethane-induced tumors in A/J mice. Dna and Cell Biology. 22: 33-40. PMID 12590735 DOI: 10.1089/104454903321112479 |
0.826 |
|
2003 |
Dwyer-Nield LD, Dinsdale D, Cohen JJ, Squier MK, Malkinson AM. Morphological assessment of apoptosis in human lung cells. Methods in Molecular Medicine. 74: 283-97. PMID 12415703 DOI: 10.1385/1-59259-323-2:283 |
0.473 |
|
2003 |
Zhang F, Pao W, Umphress S, Jackowlew S, Meyer AM, Dwyer-Nield L, Malkinson AM, Mason RJ. P-640 Serum levels of surfactant protein D are increased in mice with lung tumors Lung Cancer. 41. DOI: 10.1016/S0169-5002(03)92607-9 |
0.805 |
|
2002 |
Kisley LR, Barrett BS, Bauer AK, Dwyer-Nield LD, Barthel B, Meyer AM, Thompson DC, Malkinson AM. Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis. Cancer Research. 62: 6850-6. PMID 12460898 |
0.869 |
|
2002 |
Kisley LR, Barrett BS, Dwyer-Nield LD, Bauer AK, Thompson DC, Malkinson AM. Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice. Carcinogenesis. 23: 1653-60. PMID 12376474 DOI: 10.1093/Carcin/23.10.1653 |
0.816 |
|
2002 |
Kupfer R, Dwyer-Nield LD, Malkinson AM, Thompson JA. Lung toxicity and tumor promotion by hydroxylated derivatives of 2,6-di-tert-butyl-4-methylphenol (BHT) and 2-tert-butyl-4-methyl-6-iso-propylphenol: correlation with quinone methide reactivity. Chemical Research in Toxicology. 15: 1106-12. PMID 12184795 DOI: 10.1021/Tx0255525 |
0.44 |
|
2002 |
Malkinson AM, Radcliffe RA, Bauer AK. Quantitative trait locus mapping of susceptibilities to butylated hydroxytoluene-induced lung tumor promotion and pulmonary inflammation in CXB mice. Carcinogenesis. 23: 411-7. PMID 11895855 DOI: 10.1093/Carcin/23.3.411 |
0.773 |
|
2002 |
Keith RL, Miller YE, Hoshikawa Y, Moore MD, Gesell TL, Gao B, Malkinson AM, Golpon HA, Nemenoff RA, Geraci MW. Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer. Cancer Research. 62: 734-40. PMID 11830527 |
0.543 |
|
2002 |
Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM. Corrigendum to “Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells” Cancer Letters. 180: 223. DOI: 10.1016/S0304-3835(02)00016-2 |
0.494 |
|
2002 |
Bauer AK, Dwyer-Nield LD, Hankin JA, Murphy RC, Malkinson AM. Erratum to “The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice”: [Toxicology 169 (2001) 1–15] Toxicology. 176: 159-161. DOI: 10.1016/S0300-483X(02)00074-4 |
0.758 |
|
2001 |
Bauer AK, Dwyer-Nield LD, Hankin JA, Murphy RC, Malkinson AM. The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice Toxicology. 169: 1-15. PMID 11696405 DOI: 10.1016/S0300-483X(01)00475-9 |
0.767 |
|
2001 |
Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM. Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells. Cancer Letters. 168: 165-72. PMID 11403921 DOI: 10.1016/S0304-3835(01)00480-3 |
0.531 |
|
2001 |
Malkinson AM. Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung. Lung Cancer (Amsterdam, Netherlands). 32: 265-79. PMID 11390008 DOI: 10.1016/S0169-5002(00)00232-4 |
0.564 |
|
2001 |
Porter SE, Dwyer-Nield LD, Malkinson AM. Regulation of lung epithelial cell morphology by cAMP-dependent protein kinase type I isozyme. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L1282-9. PMID 11350809 DOI: 10.1152/Ajplung.2001.280.6.L1282 |
0.419 |
|
2001 |
McDoniels-Silvers AL, Herzog CR, Tyson FL, Malkinson AM, You M. Inactivation of both Rb and p53 pathways in mouse lung epithelial cell lines. Experimental Lung Research. 27: 297-318. PMID 11293330 DOI: 10.1080/019021401300054064 |
0.442 |
|
2001 |
Ruch RJ, Porter S, Koffler LD, Dwyer-Nield LD, Malkinson AM. Defective gap junctional intercellular communication in lung cancer: loss of an important mediator of tissue homeostasis and phenotypic regulation. Experimental Lung Research. 27: 231-43. PMID 11293326 DOI: 10.1080/019021401300053984 |
0.525 |
|
2001 |
Bauer AK, Dwyer-Nield LD, Keil K, Koski K, Malkinson AM. Butylated hydroxytoluene (BHT) induction of pulmonary inflammation: a role in tumor promotion. Experimental Lung Research. 27: 197-216. PMID 11293324 DOI: 10.1080/019021401300053948 |
0.777 |
|
2001 |
Thompson JA, Carlson TJ, Sun Y, Dwyer-Nield LD, Malkinson AM. Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion. Toxicology. 160: 197-205. PMID 11246140 DOI: 10.1016/S0300-483X(00)00449-2 |
0.594 |
|
2000 |
Miller MS, Gressani KM, Leone-Kabler S, Townsend AJ, Malkinson AM, O'Sullivan MG. Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters. Experimental Lung Research. 26: 709-30. PMID 11195466 DOI: 10.1080/01902140150216774 |
0.575 |
|
2000 |
Koffler L, Roshong S, Kyu Park I, Cesen-Cummings K, Thompson DC, Dwyer-Nield LD, Rice P, Mamay C, Malkinson AM, Ruch RJ. Growth inhibition in G(1) and altered expression of cyclin D1 and p27(kip-1 )after forced connexin expression in lung and liver carcinoma cells. Journal of Cellular Biochemistry. 79: 347-54. PMID 10972973 DOI: 10.1002/1097-4644(20001201)79:3<347::Aid-Jcb10>3.0.Co;2-2 |
0.41 |
|
2000 |
Dwyer-Nield LD, Paigen B, Porter SE, Malkinson AM. Quantitative trait locus mapping of genes regulating pulmonary PKC activity and PKC-alpha content. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L326-32. PMID 10926556 DOI: 10.1152/Ajplung.2000.279.2.L326 |
0.418 |
|
2000 |
Blaxall BC, Dwyer-Nield LD, Bauer AK, Bohlmeyer TJ, Malkinson AM, Port JD. Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissue. Molecular Carcinogenesis. 28: 76-83. PMID 10900464 DOI: 10.1002/1098-2744(200006)28:2<76::Aid-Mc3>3.0.Co;2-0 |
0.687 |
|
2000 |
Malkinson AM, Bauer A, Meyer A, Dwyer-Nield L, Koski K, Keith R, Geraci M, Miller Y-. Experimental Evidence From an Animal Model of Adenocarcinoma That Chronic Inflammation Enhances Lung Cancer Risk Chest. 117: 228. PMID 10843922 DOI: 10.1378/Chest.117.5_Suppl_1.228S |
0.81 |
|
2000 |
Bauer AK, Dwyer-Nield LD, Malkinson AM. High cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) contents in mouse lung tumors. Carcinogenesis. 21: 543-50. PMID 10753183 DOI: 10.1093/Carcin/21.4.543 |
0.787 |
|
2000 |
Mason RJ, Kalina M, Nielsen LD, Malkinson AM, Shannon JM. Surfactant protein C expression in urethane-induced murine pulmonary tumors American Journal of Pathology. 156: 175-182. PMID 10623665 DOI: 10.1016/S0002-9440(10)64717-7 |
0.465 |
|
2000 |
Gressani KM, Leone-Kabler S, O'Sullivan MG, Case LD, Malkinson AM, Miller MS. Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene. Carcinogenesis. 20: 2159-65. PMID 10545420 DOI: 10.1093/Carcin/20.11.2159 |
0.544 |
|
2000 |
Keith R, Miller Y, Gesell T, Moore M, Malkinson A, Geraci M. Selective pulmonary prostacyclin synthase overexpression chemoprevents murine lung cancer and alters global gene expression Lung Cancer. 29: 220. DOI: 10.1016/S0169-5002(00)80752-7 |
0.491 |
|
1999 |
Rice PL, Porter SE, Koski KM, Ramakrishna G, Chen A, Schrump D, Kazlauskas A, Malkinson AM. Reduced receptor expression for platelet-derived growth factor and epidermal growth factor in dividing mouse lung epithelial cells. Molecular Carcinogenesis. 25: 285-94. PMID 10449035 DOI: 10.1002/(Sici)1098-2744(199908)25:4<285::Aid-Mc7>3.0.Co;2-F |
0.442 |
|
1999 |
Dwyer-Nield LD, Thompson JA, Peljak G, Squier MK, Barker TD, Parkinson A, Cohen JJ, Dinsdale D, Malkinson AM. Selective induction of apoptosis in mouse and human lung epithelial cell lines by the tert-butyl hydroxylated metabolite of butylated hydroxytoluene: a proposed role in tumor promotion. Toxicology. 130: 115-27. PMID 9865479 DOI: 10.1016/S0300-483X(98)00102-4 |
0.577 |
|
1998 |
Thompson DC, Porter SE, Bauer AK, Das KC, Ou B, Dwyer-Nield L, White CW, Malkinson AM. Cytokine-induced nitric oxide formation in normal but not in neoplastic murine lung epithelial cell lines. American Journal of Physiology. Lung Cellular and Molecular Physiology. 274: L922-L932. PMID 29591861 DOI: 10.1152/ajplung.1998.274.6.L922 |
0.725 |
|
1998 |
Festing MF, Lin L, Devereux TR, Gao F, Yang A, Anna CH, White CM, Malkinson AM, You M. At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice. Genomics. 53: 129-36. PMID 9790761 DOI: 10.1006/Geno.1998.5450 |
0.462 |
|
1998 |
Malkinson AM, Koski KM, Dwyer-Nield LD, Rice PL, Rioux N, Castonguay A, Ahnen DJ, Thompson H, Pamukcu R, Piazza GA. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumor formation by FGN-1 (sulindac sulfone). Carcinogenesis. 19: 1353-6. PMID 9744528 DOI: 10.1093/Carcin/19.8.1353 |
0.564 |
|
1998 |
Malkinson AM. Molecular comparison of human and mouse pulmonary adenocarcinomas. Experimental Lung Research. 24: 541-555. PMID 9659582 DOI: 10.3109/01902149809087385 |
0.453 |
|
1998 |
Ruch RJ, Cesen-Cummings K, Malkinson AM. Role of gap junctions in lung neoplasia. Experimental Lung Research. 24: 523-39. PMID 9659581 DOI: 10.3109/01902149809087384 |
0.523 |
|
1998 |
Lin L, Festing MF, Devereux TR, Crist KA, Christiansen SC, Wang Y, Yang A, Svenson K, Paigen B, Malkinson AM, You M. Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene. Experimental Lung Research. 24: 481-97. PMID 9659579 DOI: 10.3109/01902149809087382 |
0.422 |
|
1998 |
Thompson DC, Porter SE, Bauer AK, Das KC, Ou B, Dwyer-Nield L, White CW, Malkinson AM. Cytokine-induced nitric oxide formation in normal but not in neoplastic murine lung epithelial cell lines. The American Journal of Physiology. 274: L922-32. PMID 9609731 DOI: 10.1152/Ajplung.1998.274.6.L922 |
0.746 |
|
1998 |
Oreffo VI, Robinson S, You M, Wu MC, Malkinson AM. Decreased expression of the adenomatous polyposis coli (Apc) and mutated in colorectal cancer (Mcc) genes in mouse lung neoplasia. Molecular Carcinogenesis. 21: 37-49. PMID 9473770 DOI: 10.1002/(Sici)1098-2744(199801)21:1<37::Aid-Mc6>3.0.Co;2-M |
0.558 |
|
1998 |
Cesen-Cummings K, Fernstrom MJ, Malkinson AM, Ruch RJ. Frequent reduction of gap junctional intercellular communication and connexin43 expression in human and mouse lung carcinoma cells. Carcinogenesis. 19: 61-7. PMID 9472694 DOI: 10.1093/Carcin/19.1.61 |
0.485 |
|
1997 |
Malkinson AM, Dwyer-Nield LD, Rice PL, Dinsdale D. Mouse lung epithelial cell lines-tools for the study of differentiation and the neoplastic phenotype Toxicology. 123: 53-100. PMID 9347924 DOI: 10.1016/S0300-483X(97)00108-X |
0.533 |
|
1997 |
Horio Y, Chen A, Rice P, Roth JA, Malkinson AM, Schrump DS. Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. Molecular Carcinogenesis. 17: 217-23. PMID 8989915 DOI: 10.1002/(Sici)1098-2744(199612)17:4<217::Aid-Mc5>3.0.Co;2-A |
0.376 |
|
1997 |
Schrump D, Chen A, Consuli U, Malkinson A, Roth J. 554 Cyclin D1 ribozyme inhibits the proliferation of urethane induced lung cancer cells containing activated K-ras Lung Cancer. 18: 142. DOI: 10.1016/S0169-5002(97)89934-5 |
0.433 |
|
1996 |
Dwyer-Nield LD, Miller AC, Neighbors BW, Dinsdale D, Malkinson AM. Cytoskeletal architecture in mouse lung epithelial cells is regulated by protein-kinase C-alpha and calpain II. The American Journal of Physiology. 270: L526-34. PMID 8928811 DOI: 10.1152/Ajplung.1996.270.4.L526 |
0.385 |
|
1995 |
Festing MF, Yang A, Malkinson AM. At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice. Genetical Research. 64: 99-106. PMID 7813906 DOI: 10.1017/S0016672300032705 |
0.407 |
|
1995 |
Miller AC, Dwyer-Nield LD, Malkinson AM. Very early changes in pulmonary protein kinase C-alpha and calpain II contents following injection of butylated hydroxytoluene (BHT) into mice. Toxicology. 97: 141-9. PMID 7716780 DOI: 10.1016/0300-483X(94)02943-O |
0.465 |
|
1995 |
Guan X, Hardenbrook J, Fernstrom MJ, Chaudhuri R, Malkinson AM, Ruch RJ. Down-regulation by butylated hydroxytoluene of the number and function of gap junctions in epithelial cell lines derived from mouse lung and rat liver. Carcinogenesis. 16: 2575-82. PMID 7586169 DOI: 10.1093/Carcin/16.10.2575 |
0.443 |
|
1994 |
Dwyer LD, Miller AC, Parks AL, Jaken S, Malkinson AM. Calpain-induced downregulation of activated protein kinase C-alpha affects lung epithelial cell morphology. The American Journal of Physiology. 266: L569-76. PMID 8203550 DOI: 10.1152/Ajplung.1994.266.5.L569 |
0.426 |
|
1994 |
Miller AC, Dwyer LD, Auerbach CE, Miley FB, Dinsdale D, Malkinson AM. Strain-related differences in the pneumotoxic effects of chronically administered butylated hydroxytoluene on protein kinase C and calpain. Toxicology. 90: 141-59. PMID 8023339 DOI: 10.1016/0300-483X(94)90212-7 |
0.495 |
|
1993 |
Droms KA, Hanson LA, Malkinson AM, Beer DG. Altered dexamethasone responsiveness and loss of growth control in tumorigenic mouse lung cell lines. International Journal of Cancer. 53: 1017-22. PMID 8473042 DOI: 10.1002/ijc.2910530627 |
0.334 |
|
1993 |
Chaudhuri R, Sigler K, Dupont E, Trosko JE, Malkinson AM, Ruch RJ. Gap junctional intercellular communication in mouse lung epithelial cell lines: effects of cell transformation and tumor promoters. Cancer Letters. 71: 11-8. PMID 8395972 DOI: 10.1016/0304-3835(93)90090-V |
0.566 |
|
1993 |
Bolton JL, Thompson JA, Allentoff AJ, Miley FB, Malkinson AM. Metabolic Activation of Butylated Hydroxytoluene by Mouse Bronchiolar Clara Cells Toxicology and Applied Pharmacology. 123: 43-49. PMID 8236260 DOI: 10.1006/Taap.1993.1219 |
0.451 |
|
1993 |
Blumenthal EJ, Miller AC, Stein GH, Malkinson AM. Serine/threonine protein kinases and calcium-dependent protease in senescent IMR-90 fibroblasts. Mechanisms of Ageing and Development. 72: 13-24. PMID 8114516 DOI: 10.1016/0047-6374(93)90127-D |
0.303 |
|
1993 |
Lange-Carter CA, Droms KA, Vuillequez JJ, Malkinson AM. Differential responsiveness to agents which stimulate cAMP production in normal versus neoplastic mouse lung epithelial cells. Cancer Letters. 67: 139-44. PMID 1336430 DOI: 10.1016/0304-3835(92)90137-K |
0.486 |
|
1992 |
Malkinson AM. Genetic studies on lung tumor susceptibility and histogenesis in mice. Environmental Health Perspectives. 93: 149-59. PMID 1773786 DOI: 10.1289/Ehp.9193149 |
0.576 |
|
1992 |
Reiners JJ, Pavone A, Cantu AR, Auerbach C, Malkinson AM. Differential expression of cytochrome P-450 in proliferating and quiescent cultures of murine lung epithelial cells. Biochemical and Biophysical Research Communications. 183: 193-8. PMID 1543490 DOI: 10.1016/0006-291X(92)91627-3 |
0.374 |
|
1991 |
Nuzum EO, Malkinson AM, Beer DG. Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas. Molecular Carcinogenesis. 3: 287-95. PMID 2244961 DOI: 10.1002/Mc.2940030509 |
0.545 |
|
1991 |
Thompson JA, Bolton JL, Malkinson AM. Relationship between the metabolism of butylated hydroxytoluene (BHT) and lung tumor promotion in mice Experimental Lung Research. 17: 439-453. PMID 2050043 DOI: 10.3109/01902149109064431 |
0.577 |
|
1991 |
Malkinson AM. Promoters, co-carcinogens and inhibitors of pulmonary carcinogenesis in mice: an overview. Experimental Lung Research. 17: 435-7. PMID 2050042 DOI: 10.3109/01902149109064430 |
0.518 |
|
1991 |
Hanson LA, Nuzum EO, Jones BC, Malkinson AM, Beer DG. Expression of the glucocorticoid receptor and K-ras genes in urethan-induced mouse lung tumors and transformed cell lines. Experimental Lung Research. 17: 371-87. PMID 2050037 DOI: 10.3109/01902149109064425 |
0.423 |
|
1991 |
Droms KA, Malkinson AM. Mechanisms of glucocorticoid involvement in mouse lung tumorigenesis. Experimental Lung Research. 17: 359-70. PMID 2050036 DOI: 10.3109/01902149109064424 |
0.618 |
|
1991 |
Thaete LG, Malkinson AM. Cells of origin of primary pulmonary neoplasms in mice: morphologic and histochemical studies. Experimental Lung Research. 17: 219-28. PMID 2050027 DOI: 10.3109/01902149109064413 |
0.534 |
|
1991 |
Droms KA, Malkinson AM. Phorbol ester-induced tumor promotion by downregulation of protein kinase C. Molecular Carcinogenesis. 4: 1-2. PMID 2009129 DOI: 10.1002/Mc.2940040102 |
0.361 |
|
1991 |
Thaete LG, Siegel D, Malkinson AM, Forrest GL, Ross D. NAD(P)H:quinone oxidoreductase (DT-diaphorase) activity and mRNA content in normal and neoplastic mouse lung epithelia. International Journal of Cancer. 49: 145-9. PMID 1908440 DOI: 10.1002/Ijc.2910490126 |
0.614 |
|
1991 |
Lange-Carter CA, Malkinson AM. Alterations in the cAMP signal transduction pathway in mouse lung tumorigenesis. Experimental Lung Research. 17: 341-57. PMID 1646708 DOI: 10.3109/01902149109064423 |
0.404 |
|
1990 |
Thaete LG, Malkinson AM. Differential staining of normal and neoplastic mouse lung epithelia by succinate dehydrogenase histochemistry. Cancer Letters. 52: 219-27. PMID 2379144 DOI: 10.1016/0304-3835(90)90190-9 |
0.533 |
|
1990 |
Thaete LG, Nesbitt MN, Malkinson AM. Genetic Analysis of the Distribution of Corticosterone-Containing Cells in Mouse Adrenal Cortex Proceedings of the Society For Experimental Biology and Medicine. 194: 97-102. PMID 2349252 DOI: 10.3181/00379727-194-43062 |
0.339 |
|
1989 |
Witschi H, Malkinson AM, Peraino C, Russell JJ, Staffeld EF. Effects of glycerol on lung and liver tumor development. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 13: 174-80. PMID 2767358 DOI: 10.1016/0272-0590(89)90317-5 |
0.563 |
|
1989 |
Walker SR, Hale S, Malkinson AM, Mason RJ. Properties of isolated nonciliated bronchiolar cells from mouse lung. Experimental Lung Research. 15: 553-73. PMID 2767004 DOI: 10.3109/01902148909069618 |
0.433 |
|
1989 |
Thompson JA, Schullek KM, Fernandez CA, Malkinson AM. A metabolite of butylated hydroxytoluene with potent tumor-promoting activity in mouse lung Carcinogenesis. 10: 773-775. PMID 2702725 DOI: 10.1093/Carcin/10.4.773 |
0.585 |
|
1989 |
Malkinson AM. The genetic basis of susceptibility to lung tumors in mice. Toxicology. 54: 241-71. PMID 2650016 DOI: 10.1016/0300-483X(89)90062-0 |
0.531 |
|
1989 |
Thaete LG, Ahnen DJ, Malkinson AM. Proliferating cell nuclear antigen (PCNA/cyclin) immunocytochemistry as a labeling index in mouse lung tissues. Cell and Tissue Research. 256: 167-73. PMID 2565770 DOI: 10.1007/Bf00224731 |
0.523 |
|
1989 |
Malkinson AM, Thaete LG, Blumenthal EJ, Thompson JA. Evidence for a role of tert-butyl hydroxylation in the induction of pneumotoxicity in mice by butylated hydroxytoluene. Toxicology and Applied Pharmacology. 101: 196-204. PMID 2554532 DOI: 10.1016/0041-008X(89)90269-X |
0.499 |
|
1989 |
Droms KA, Haley BE, Smith GJ, Malkinson AM. Decreased 8N3-[γ-32P]GTP photolabeling of Gsα in tumorigenic lung epithelial cell lines: Association with decreased hormone responsiveness and loss of contact-inhibited growth Experimental Cell Research. 182: 330-339. PMID 2542068 DOI: 10.1016/0014-4827(89)90238-3 |
0.479 |
|
1989 |
WITSCHI H, MALKINSON AM, PERAINO C, RUSSELL JJ, STAFFELDT EF. Effects of Glycerol on Lung and Liver Tumor Development Toxicological Sciences. 13: 174-180. DOI: 10.1093/toxsci/13.1.174 |
0.44 |
|
1988 |
Siegel D, Malkinson AM, Ross D. Butylated hydroxytoluene (BHT)-mediated increases in NAD(P)H-quinone oxidoreductase (QR) in mouse lung: evidence for the alveolar type II cell as a site of QR activity. Toxicology and Applied Pharmacology. 96: 68-74. PMID 3142099 DOI: 10.1016/0041-008X(88)90248-7 |
0.56 |
|
1988 |
Droms KA, Fernandez CA, Thaete LG, Malkinson AM. Effects of adrenalectomy and corticosterone administration on mouse lung tumor susceptibility and histogenesis Journal of the National Cancer Institute. 80: 365-369. PMID 2895816 DOI: 10.1093/jnci/80.5.365 |
0.46 |
|
1988 |
Blumenthal EJ, Malkinson AM. Age-dependent changes in murine protein kinase and protease enzymes. Mechanisms of Ageing and Development. 46: 201-17. PMID 2852280 DOI: 10.1016/0047-6374(88)90125-X |
0.376 |
|
1987 |
Malkinson AM, Girard PR, Kuo JF. Strain-specific postnatal changes in the activity and tissue levels of protein kinase C. Biochemical and Biophysical Research Communications. 145: 733-9. PMID 3593366 DOI: 10.1016/0006-291X(87)91026-6 |
0.396 |
|
1987 |
Droms KA, Haley BE, Malkinson AM. Decreased incorporation of the photoaffinity probe 8N3-[γ-32P]-GTP into a 45KD protein in lung tumors Biochemical and Biophysical Research Communications. 144: 591-597. PMID 3579932 DOI: 10.1016/S0006-291X(87)80007-4 |
0.551 |
|
1987 |
Blumenthal EJ, Malkinson AM. Changes in pulmonary calpain activity following treatment of mice with butylated hydroxytoluene. Archives of Biochemistry and Biophysics. 256: 19-28. PMID 3038020 DOI: 10.1016/0003-9861(87)90421-8 |
0.473 |
|
1987 |
Malkinson AM, Haley BE, Macintyre BE, Butley MS. Changes in pulmonary ATP-binding proteins induced by treating mice with butylated hydroxytoluene Chest. 91. DOI: 10.1378/Chest.91.3_Supplement.8S |
0.369 |
|
1987 |
Thaete LG, Gunning WT, Stoner GD, Malkinson AM. Cellular Derivation of Lung Tumors in Sensitive and Resistant Strains of Mice: Results at 28 and 56 Weeks After Urethan Treatment Journal of the National Cancer Institute. 78: 743-749. DOI: 10.1093/Jnci/78.4.743 |
0.5 |
|
1985 |
Malkinson AM, Nesbitt MN, Skamene E. Susceptibility to urethan-induced pulmonary adenomas between a/j and c57bl/6j mice: Use of axb and bxa recombinant inbred lines indicating a three-locus genetic model Journal of the National Cancer Institute. 75: 971-974. PMID 3863994 DOI: 10.1093/Jnci/75.5.971 |
0.5 |
|
1985 |
Beer DG, Malkinson AM. Genetic influence on type 2 or Clara cell origin of pulmonary adenomas in urethan-treated mice. Journal of the National Cancer Institute. 75: 963-9. PMID 3863993 DOI: 10.1093/Jnci/75.5.963 |
0.552 |
|
1984 |
Beer DG, Butley MS, Cunha GR, Malkinson AM. Autoradiographic localization of specific [3H]dexamethasone binding in fetal lung. Developmental Biology. 105: 351-64. PMID 6479444 DOI: 10.1016/0012-1606(84)90292-6 |
0.466 |
|
1984 |
Beer DG, Butley MS, Malkinson AM. Developmental changes in the endogenous Ca2+-stimulated proteolysis of mouse lung cAMP-dependent protein kinases. Archives of Biochemistry and Biophysics. 228: 207-19. PMID 6320733 DOI: 10.1016/0003-9861(84)90062-6 |
0.392 |
|
1984 |
Malkinson AM, Conway K, Bartlett S, Butley MS, Conroy C. Strain differences among inbred mice in protein kinase C activity. Biochemical and Biophysical Research Communications. 122: 492-8. PMID 6235809 DOI: 10.1016/S0006-291X(84)80060-1 |
0.349 |
|
1984 |
Gunning WT, Stoner GD, Malkinson AM, Goldblatt PJ. Cellular origin of urethane-induced lung tumors in strain a mice Micron and Microscopica Acta. 15: 103-104. DOI: 10.1016/0739-6260(84)90011-X |
0.574 |
|
1983 |
Malkinson AM. Review: putative mutagens and carcinogens in foods. III. Butylated hydroxytoluene (BHT). Environmental Mutagenesis. 5: 353-362. PMID 6343068 DOI: 10.1002/Em.2860050313 |
0.385 |
|
1983 |
Malkinson AM, Beer DS. Major Effect on Susceptibility to Urethan-lnduced Pulmonary Adenoma by a Single Gene in BALB/cBy Mice Journal of the National Cancer Institute. 70: 931-936. DOI: 10.1093/Jnci/70.5.931 |
0.453 |
|
1979 |
Malkinson AM. Prevention of butylated hydroxytoluene-induced lung damage in mice by cedar terpene administration. Toxicology and Applied Pharmacology. 49: 551-60. PMID 473220 DOI: 10.1016/0041-008X(79)90457-5 |
0.48 |
|
1979 |
Malkinson AM. Altered phosphorylation of lung proteins following administration of butylated hydroxytoluene (BHT) to mice. Life Sciences. 24: 465-71. PMID 219311 DOI: 10.1016/0024-3205(79)90219-4 |
0.532 |
|
1978 |
Malkinson AM, Gunderson TJ, McSwigan CE. Protein phosphorylation in normal and neoplastic development. Cyclic AMP-dependent protein kinase activity in urethane-induced pulmonary tumours. The Biochemical Journal. 168: 319-21. PMID 202267 DOI: 10.1042/bj1680319 |
0.36 |
|
1969 |
Malkinson AM, Hardman JK. Structural and functional roles of the cysteine residues in the alpha subunit of the Escherichia coli tryptophan synthetase. I. Structural roles and reactivity of the cysteine residues. Biochemistry. 8: 2769-76. PMID 4980105 DOI: 10.1021/bi00835a012 |
0.553 |
|
1969 |
Malkinson AM, Hardman JK. Structural and functional roles of the cysteine residues in the alpha subunit of the Escherichia coli trypotphan synthetase. II. Functional roles of the cysteine residues. Biochemistry. 8: 2777-81. PMID 4897205 DOI: 10.1021/bi00835a013 |
0.555 |
|
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