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Travis L. Biechele, Ph.D. - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Wnt signaling
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, et al. Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. Cell Chemical Biology. PMID 33503403 DOI: 10.1016/j.chembiol.2021.01.001  0.599
2014 Chien AJ, Haydu LE, Biechele TL, Kulikauskas RM, Rizos H, Kefford RF, Scolyer RA, Moon RT, Long GV. Targeted BRAF inhibition impacts survival in melanoma patients with high levels of Wnt/β-catenin signaling. Plos One. 9: e94748. PMID 24733413 DOI: 10.1371/Journal.Pone.0094748  0.62
2014 Robin NC, Agoston Z, Biechele TL, James RG, Berndt JD, Moon RT. Simvastatin promotes adult hippocampal neurogenesis by enhancing Wnt/β-catenin signaling. Stem Cell Reports. 2: 9-17. PMID 24511465 DOI: 10.1016/J.Stemcr.2013.11.002  0.789
2013 James RG, Bosch KA, Kulikauskas RM, Yang PT, Robin NC, Toroni RA, Biechele TL, Berndt JD, von Haller PD, Eng JK, Wolf-Yadlin A, Chien AJ, Moon RT. Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells. The Journal of Biological Chemistry. 288: 34658-70. PMID 24114839 DOI: 10.1074/Jbc.M113.500314  0.794
2012 James RG, Davidson KC, Bosch KA, Biechele TL, Robin NC, Taylor RJ, Major MB, Camp ND, Fowler K, Martins TJ, Moon RT. WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling. Plos One. 7: e50457. PMID 23227175 DOI: 10.1371/Journal.Pone.0050457  0.795
2012 Conrad WH, Swift RD, Biechele TL, Kulikauskas RM, Moon RT, Chien AJ. Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation. Cell Cycle (Georgetown, Tex.). 11: 3724-30. PMID 22895053 DOI: 10.4161/Cc.21645  0.808
2012 Davidson KC, Adams AM, Goodson JM, McDonald CE, Potter JC, Berndt JD, Biechele TL, Taylor RJ, Moon RT. Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4. Proceedings of the National Academy of Sciences of the United States of America. 109: 4485-90. PMID 22392999 DOI: 10.1073/Pnas.1118777109  0.686
2012 Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ. Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma. Science Signaling. 5: ra3. PMID 22234612 DOI: 10.1126/Scisignal.2002274  0.82
2012 Anastas JN, Biechele TL, Robitaille M, Muster J, Allison KH, Angers S, Moon RT. A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene. 31: 3696-708. PMID 22179838 DOI: 10.1038/Onc.2011.528  0.743
2012 Biechele TL, Chien AJ, Moon RT, VanHook AM. Science Signaling Podcast: 10 January 2012 Science Signaling. 5: pc1-pc1. DOI: 10.1126/Scisignal.2002784  0.543
2011 Zhou W, Dosey TL, Biechele T, Moon RT, Horwitz MS, Ruohola-Baker H. Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct. Plos One. 6: e27460. PMID 22132102 DOI: 10.1371/Journal.Pone.0027460  0.573
2011 Oikonomopoulos A, Sereti KI, Conyers F, Bauer M, Liao A, Guan J, Crapps D, Han JK, Dong H, Bayomy AF, Fine GC, Westerman K, Biechele TL, Moon RT, Force T, et al. Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3. Circulation Research. 109: 1363-74. PMID 22034491 DOI: 10.1161/Circresaha.111.250282  0.61
2011 Cheng Z, Biechele T, Wei Z, Morrone S, Moon RT, Wang L, Xu W. Crystal structures of the extracellular domain of LRP6 and its complex with DKK1. Nature Structural & Molecular Biology. 18: 1204-10. PMID 21984209 DOI: 10.1038/Nsmb.2139  0.556
2011 Lyashenko N, Winter M, Migliorini D, Biechele T, Moon RT, Hartmann C. Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation. Nature Cell Biology. 13: 753-61. PMID 21685890 DOI: 10.1038/Ncb2260  0.648
2011 Pan JQ, Lewis MC, Ketterman JK, Clore EL, Riley M, Richards KR, Berry-Scott E, Liu X, Wagner FF, Holson EB, Neve RL, Biechele TL, Moon RT, Scolnick EM, Petryshen TL, et al. AKT kinase activity is required for lithium to modulate mood-related behaviors in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1397-411. PMID 21389981 DOI: 10.1038/Npp.2011.24  0.553
2011 Biechele TL, Chien AJ. Re: Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol. Carcinogenesis. 32: 120; author reply 12. PMID 20980347 DOI: 10.1093/Carcin/Bgq217  0.584
2010 Biechele TL, Camp ND, Fass DM, Kulikauskas RM, Robin NC, White BD, Taraska CM, Moore EC, Muster J, Karmacharya R, Haggarty SJ, Chien AJ, Moon RT. Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma. Chemistry & Biology. 17: 1177-82. PMID 21095567 DOI: 10.1016/J.Chembiol.2010.08.012  0.774
2010 Cimetta E, Cannizzaro C, James R, Biechele T, Moon RT, Elvassore N, Vunjak-Novakovic G. Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling. Lab On a Chip. 10: 3277-83. PMID 20936235 DOI: 10.1039/C0Lc00033G  0.634
2009 Biechele TL, Adams AM, Moon RT. Transcription-based reporters of Wnt/beta-catenin signaling. Cold Spring Harbor Protocols. 2009: pdb.prot5223. PMID 20147181 DOI: 10.1101/Pdb.Prot5223  0.686
2009 Kategaya LS, Changkakoty B, Biechele T, Conrad WH, Kaykas A, Dasgupta R, Moon RT. Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6. Plos One. 4: e6129. PMID 19572019 DOI: 10.1371/Journal.Pone.0006129  0.781
2009 James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Science Signaling. 2: ra25. PMID 19471023 DOI: 10.1126/Scisignal.2000230  0.822
2009 Berndt JD, Biechele TL, Moon RT, Major MB. Integrative analysis of genome-wide RNA interference screens. Science Signaling. 2: pt4. PMID 19436058 DOI: 10.1126/Scisignal.270Pt4  0.536
2009 Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C, Berry EM, Soda T, Singh KK, Biechele T, Petryshen TL, Moon RT, Haggarty SJ, Tsai LH. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell. 136: 1017-31. PMID 19303846 DOI: 10.1016/J.Cell.2008.12.044  0.646
2008 Biechele TL, Moon RT. Assaying beta-catenin/TCF transcription with beta-catenin/TCF transcription-based reporter constructs. Methods in Molecular Biology (Clifton, N.J.). 468: 99-110. PMID 19099249 DOI: 10.1007/978-1-59745-249-6_8  0.659
2008 Woll PS, Morris JK, Painschab MS, Marcus RK, Kohn AD, Biechele TL, Moon RT, Kaufman DS. Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells. Blood. 111: 122-31. PMID 17875805 DOI: 10.1182/Blood-2007-04-084186  0.573
2007 De Ferrari GV, Papassotiropoulos A, Biechele T, Wavrant De-Vrieze F, Avila ME, Major MB, Myers A, Sáez K, Henríquez JP, Zhao A, Wollmer MA, Nitsch RM, Hock C, Morris CM, Hardy J, et al. Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 9434-9. PMID 17517621 DOI: 10.1073/Pnas.0603523104  0.56
2007 Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science (New York, N.Y.). 316: 1043-6. PMID 17510365 DOI: 10.1126/Science/1141515  0.813
2006 Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT. The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nature Cell Biology. 8: 348-57. PMID 16547521 DOI: 10.1038/Ncb1381  0.77
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