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Mavis Agbandje-McKenna - Publications

Affiliations: 
Biochemistry and Molecular Biology University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Medical Biophysics
Website:
http://biochem.med.ufl.edu/research/primary-faculty/mavis-agbandje-mckenna/
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242 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li L, Qin R, Liu Y, Tseng YS, Zhang W, Yu L, Mietzsch M, Zou X, Liu H, Lu G, Hu H, Mckenna R, Yang J, Wei Y, Agbandje-Mckenna M, et al. Dissecting positive selection events and immunological drives during the evolution of adeno-associated virus lineages. Plos Pathogens. 20: e1012260. PMID 38885242 DOI: 10.1371/journal.ppat.1012260  0.483
2024 Lakshmanan RV, Agbandje-McKenna M, McKenna R. Feasibility of Domain Segmentation of B19V VP1u Using Intein Technology for Structural Studies. Protein and Peptide Letters. PMID 38243925 DOI: 10.2174/0109298665277211231214065419  0.47
2024 Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, ... ... Agbandje-McKenna M, et al. Overcoming resolution attenuation during tilted cryo-EM data collection. Nature Communications. 15: 389. PMID 38195598 DOI: 10.1038/s41467-023-44555-7  0.421
2023 Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, ... ... Agbandje-McKenna M, et al. Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection. Biorxiv : the Preprint Server For Biology. PMID 37503021 DOI: 10.1101/2023.07.14.548955  0.412
2023 Bennett A, Gargas J, Kansol A, Lewis J, Hsi J, Hull J, Mietzsch M, Tartaglia L, Muzyczka N, Bhattacharya N, Chipman P, Agbandje-McKenna M, McKenna R. Structural and Biophysical Analysis of Adeno-Associated Virus Serotype 2 Capsid Assembly Variants. Journal of Virology. e0177222. PMID 37310260 DOI: 10.1128/jvi.01772-22  0.552
2022 Lakshmanan RV, Hull JA, Berry L, Burg M, Bothner B, McKenna R, Agbandje-McKenna M. Structural Dynamics and Activity of B19V VP1u during the pHs of Cell Entry and Endosomal Trafficking. Viruses. 14. PMID 36146728 DOI: 10.3390/v14091922  0.439
2022 El Andari J, Renaud-Gabardos E, Tulalamba W, Weinmann J, Mangin L, Pham QH, Hille S, Bennett A, Attebi E, Bourges E, Leborgne C, Guerchet N, Fakhiri J, Krämer C, Wiedtke E, ... ... Agbandje-McKenna M, et al. Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders. Science Advances. 8: eabn4704. PMID 36129972 DOI: 10.1126/sciadv.abn4704  0.417
2022 Mietzsch M, Hull JA, Makal VE, Jimenez Ybargollin A, Yu JC, McKissock K, Bennett A, Penzes J, Lins-Austin B, Yu Q, Chipman P, Bhattacharya N, Sousa D, Strugatsky D, Tijssen P, ... ... Agbandje-McKenna M, et al. Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity. Journal of Virology. e0033522. PMID 35532224 DOI: 10.1128/jvi.00335-22  0.575
2021 Emmanuel SN, Smith JK, Hsi J, Tseng YS, Kaplan M, Mietzsch M, Chipman P, Asokan A, McKenna R, Agbandje-McKenna M. Structurally Mapping Antigenic Epitopes of Adeno-Associated Virus 9: Development of Antibody Escape Variants. Journal of Virology. JVI0125121. PMID 34757842 DOI: 10.1128/JVI.01251-21  0.806
2021 Mietzsch M, Yu JC, Hsi J, Chipman P, Broecker F, Fuming Z, Linhardt RJ, Seeberger PH, Heilbronn R, McKenna R, Agbandje-McKenna M. Structural study of AAVrh.10 Receptor and Antibody Interactions. Journal of Virology. JVI0124921. PMID 34549984 DOI: 10.1128/JVI.01249-21  0.552
2021 Bennett A, Hull J, Jolinon N, Tordo J, Moss K, Binns E, Mietzsch M, Hagemann C, Michael Linden R, Serio A, Chipman P, Sousa D, Broecker F, Seeberger P, Henckaerts E, ... ... Agbandje-McKenna M, et al. Comparative Structural, Biophysical, and Receptor Binding Study of True Type and Wild type AAV2. Journal of Structural Biology. 107795. PMID 34509611 DOI: 10.1016/j.jsb.2021.107795  0.56
2021 Mietzsch M, Eddington C, Jose A, Hsi J, Chipman P, Henley T, Choudhry M, McKenna R, Agbandje-McKenna M. Improved Genome Packaging Efficiency of AAV Vectors Using Rep Hybrids. Journal of Virology. JVI0077321. PMID 34287038 DOI: 10.1128/JVI.00773-21  0.473
2021 Penzes JJ, Chipman P, Bhattacharya N, Zeher A, Huang R, McKenna R, Agbandje-McKenna M. AAV9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment. Journal of Virology. JVI0084321. PMID 34260280 DOI: 10.1128/JVI.00843-21  0.523
2021 Havlik LP, Das A, Mietzsch M, Oh DK, Ark J, McKenna R, Agbandje-McKenna M, Asokan A. Receptor switching in newly evolved adeno-associated viruses. Journal of Virology. JVI0058721. PMID 34232726 DOI: 10.1128/JVI.00587-21  0.532
2021 Yu JC, Mietzsch M, Singh A, Jimenez Ybargollin A, Kailasan S, Chipman P, Bhattacharya N, Fakhiri J, Grimm D, Kapoor A, Kučinskaitė-Kodzė I, Žvirblienė A, Söderlund-Venermo M, McKenna R, Agbandje-McKenna M. Characterization of the GBoV1 Capsid and Its Antibody Interactions. Viruses. 13. PMID 33672786 DOI: 10.3390/v13020330  0.8
2021 Luo M, Mietzsch M, Chipman P, Song K, Xu C, Spear J, Sousa D, McKenna R, Söderlund-Venermo M, Agbandje-McKenna M. pH-Induced Conformational Changes of Human Bocavirus Capsids. Journal of Virology. PMID 33472934 DOI: 10.1128/JVI.02329-20  0.543
2021 Mietzsch M, Jose A, Chipman P, Bhattacharya N, Daneshparvar N, McKenna R, Agbandje-McKenna M. Completion of the AAV Structural Atlas: Serotype Capsid Structures Reveals Clade-Specific Features. Viruses. 13. PMID 33450892 DOI: 10.3390/v13010101  0.589
2020 Mietzsch M, Smith JK, Yu JC, Banala V, Emmanuel SN, Jose A, Chipman P, Bhattacharya N, McKenna R, Agbandje-McKenna M. Characterization of AAV-Specific Affinity Ligands: Consequences for Vector Purification and Development Strategies. Molecular Therapy. Methods & Clinical Development. 19: 362-373. PMID 33145372 DOI: 10.1016/j.omtm.2020.10.001  0.528
2020 Hildebrandt E, Penzes JJ, Gifford RJ, Agbandje-Mckenna M, Kotin RM. Evolution of dependoparvoviruses across geological timescales-implications for design of AAV-based gene therapy vectors. Virus Evolution. 6: veaa043. PMID 32913662 DOI: 10.1093/Ve/Veaa043  0.406
2020 Cabanes-Creus M, Hallwirth CV, Westhaus A, Ng BH, Liao SHY, Zhu E, Navarro RG, Baltazar G, Drouyer M, Scott S, Logan GJ, Santilli G, Bennett A, Ginn SL, McCaughan G, ... ... Agbandje-McKenna M, et al. Restoring the natural tropism of AAV2 vectors for human liver. Science Translational Medicine. 12. PMID 32908003 DOI: 10.1126/Scitranslmed.Aba3312  0.319
2020 Pénzes JJ, Pham HT, Chipman P, Bhattacharya N, McKenna R, Agbandje-McKenna M, Tijssen P. Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747554 DOI: 10.1073/Pnas.2008191117  0.587
2020 Havlik LP, Simon KE, Smith JK, Klinc KA, Tse LV, Oh DK, Fanous MM, Meganck RM, Mietzsch M, Agbandje-McKenna M, Asokan A. Co-evolution of AAV capsid antigenicity and tropism through a structure-guided approach. Journal of Virology. PMID 32669336 DOI: 10.1128/Jvi.00976-20  0.45
2020 Lins-Austin B, Patel S, Mietzsch M, Brooke D, Bennett A, Venkatakrishnan B, Van Vliet K, Smith AN, Long JR, McKenna R, Potter M, Byrne B, Boye SL, Bothner B, Heilbronn R, ... Agbandje-McKenna M, et al. Adeno-Associated Virus (AAV) Capsid Stability and Liposome Remodeling During Endo/Lysosomal pH Trafficking. Viruses. 12. PMID 32575696 DOI: 10.3390/V12060668  0.516
2020 Mietzsch M, McKenna R, Väisänen E, Yu JC, Ilyas M, Hull JA, Kurian J, Smith JK, Chipman P, Lasanajak Y, Smith D, Söderlund-Venermo M, Agbandje-McKenna M. Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology. Viruses. 12. PMID 32560452 DOI: 10.3390/V12060653  0.646
2020 Mietzsch M, Li Y, Kurian J, Kennon Smith J, Chipman P, McKenna R, Yang L, Agbandje-McKenna M. Structural characterization of a bat Adeno-associated virus capsid. Journal of Structural Biology. 107547. PMID 32522552 DOI: 10.1016/J.Jsb.2020.107547  0.646
2020 Cabanes-Creus M, Westhaus A, Navarro RG, Baltazar G, Zhu E, Amaya AK, Liao SHY, Scott S, Sallard E, Dilworth KL, Rybicki A, Drouyer M, Hallwirth CV, Bennett A, Santilli G, ... ... Agbandje-McKenna M, et al. Attenuation of Heparan Sulfate Proteoglycan Binding Enhances Transduction of Human Primary Hepatocytes with AAV2. Molecular Therapy. Methods & Clinical Development. 17: 1139-1154. PMID 32490035 DOI: 10.1016/J.Omtm.2020.05.004  0.394
2020 Emmanuel SN, Mietzsch M, Tseng YS, Smith JK, Agbandje-McKenna M. Parvovirus Capsid-Antibody Complex Structures Reveal Conservation of Antigenic Epitopes Across the Family. Viral Immunology. PMID 32315582 DOI: 10.1089/Vim.2020.0022  0.435
2020 Yang H, Qing K, Keeler GD, Yin L, Mietzsch M, Ling C, Hoffman BE, Agbandje-McKenna M, Tan M, Wang W, Srivastava A. Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing. Molecular Therapy. Nucleic Acids. 20: 451-458. PMID 32276210 DOI: 10.1016/J.Omtn.2020.03.009  0.355
2020 Ran G, Chen X, Xie Y, Zheng Q, Xie J, Yu C, Pittman N, Qi S, Yu FX, Agbandje-McKenna M, Srivastava A, Ling C. Site-Directed Mutagenesis Improves the Transduction Efficiency of Capsid Library-Derived Recombinant AAV Vectors. Molecular Therapy. Methods & Clinical Development. 17: 545-555. PMID 32258217 DOI: 10.1016/J.Omtm.2020.03.007  0.408
2020 Fakhiri J, Linse KP, Mietzsch M, Xu M, Schneider MA, Meister M, Schildgen O, Schnitzler P, Soderlund-Venermo M, Agbandje-McKenna M, Grimm D. Impact of natural or synthetic singletons in the capsid of human bocavirus 1 on particle infectivity and immunoreactivity. Journal of Virology. PMID 32213611 DOI: 10.1128/Jvi.00170-20  0.4
2020 Börner K, Kienle E, Huang LY, Weinmann J, Sacher A, Bayer P, Stüllein C, Fakhiri J, Zimmermann L, Westhaus A, Beneke J, Beil N, Wiedtke E, Schmelas C, Miltner D, ... ... Agbandje-McKenna M, et al. Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32105604 DOI: 10.1016/J.Ymthe.2020.02.009  0.323
2019 Bennett A, Keravala A, Makal V, Kurian J, Belbellaa B, Aeran R, Tseng YS, Sousa D, Spear J, Gasmi M, Agbandje-McKenna M. Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2. Journal of Structural Biology. 107433. PMID 31859208 DOI: 10.1016/J.Jsb.2019.107433  0.429
2019 Mietzsch M, Barnes C, Hull JA, Chipman P, Xie J, Bhattacharya N, Sousa D, McKenna R, Gao G, Agbandje-McKenna M. Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8. Journal of Virology. PMID 31826994 DOI: 10.1128/Jvi.01769-19  0.624
2019 Rivière G, Peng EQ, Brotgandel A, Andring JT, Lakshmanan RV, Agbandje-McKenna M, McKenna R, Brady LJ, Long JR. Characterization of an intermolecular quaternary interaction between discrete segments of the Streptococcus mutans adhesin P1 by NMR Spectroscopy. The Febs Journal. PMID 31782893 DOI: 10.1111/Febs.15158  0.427
2019 Pénzes JJ, de Souza WM, Agbandje-McKenna M, Gifford RJ. An Ancient Lineage of Highly Divergent Parvoviruses Infects both Vertebrate and Invertebrate Hosts. Viruses. 11. PMID 31174309 DOI: 10.3390/V11060525  0.335
2019 Kurian JJ, Lakshmanan R, Chmely WM, Hull JA, Yu JC, Bennett A, McKenna R, Agbandje-McKenna M. Adeno-Associated Virus VP1u Exhibits Protease Activity. Viruses. 11. PMID 31035643 DOI: 10.3390/V11050399  0.524
2019 Mietzsch M, Pénzes JJ, Agbandje-McKenna M. . Viruses. 11. PMID 31010002 DOI: 10.3390/V11040362  0.471
2019 Guenther CM, Brun MJ, Bennett AD, Ho ML, Chen W, Zhu B, Lam M, Yamagami M, Kwon S, Bhattacharya N, Sousa D, Evans AC, Voss J, Sevick-Muraca EM, Agbandje-McKenna M, et al. Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30772143 DOI: 10.1016/J.Ymthe.2019.01.015  0.394
2019 Cotmore SF, Agbandje-McKenna M, Canuti M, Chiorini JA, Eis-Hubinger AM, Hughes J, Mietzsch M, Modha S, Ogliastro M, Pénzes JJ, Pintel DJ, Qiu J, Soderlund-Venermo M, Tattersall P, Tijssen P, et al. ICTV Virus Taxonomy Profile: Parvoviridae. The Journal of General Virology. PMID 30672729 DOI: 10.1099/Jgv.0.001212  0.377
2018 Jose A, Mietzsch M, Smith K, Kurian J, Chipman P, McKenna R, Chiorini J, Agbandje-McKenna M. High resolution structural characterization of a new AAV5 antibody epitope toward engineering antibody resistant recombinant gene delivery vectors. Journal of Virology. PMID 30333169 DOI: 10.1128/Jvi.01394-18  0.596
2018 Bennett A, Rodriguez D, Lister S, Boulton M, McKenna R, Agbandje-McKenna M. Assembly and disassembly intermediates of maize streak geminivirus. Virology. 525: 224-236. PMID 30300759 DOI: 10.1016/J.Virol.2018.09.011  0.492
2018 Tan YZ, Aiyer S, Mietzsch M, Hull JA, McKenna R, Grieger J, Samulski RJ, Baker TS, Agbandje-McKenna M, Lyumkis D. Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant. Nature Communications. 9: 3628. PMID 30194371 DOI: 10.1038/S41467-018-06076-6  0.569
2018 Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, ... ... Agbandje-McKenna M, et al. A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency. Brain : a Journal of Neurology. PMID 29788236 DOI: 10.1093/Brain/Awy126  0.391
2018 Burg M, Rosebrough C, Drouin LM, Bennett A, Mietzsch M, Chipman P, McKenna R, Sousa D, Potter M, Byrne B, Jude Samulski R, Agbandje-McKenna M. Atomic structure of a rationally engineered gene delivery vector, AAV2.5. Journal of Structural Biology. PMID 29775653 DOI: 10.1016/J.Jsb.2018.05.004  0.631
2018 Wang D, Li S, Gessler DJ, Xie J, Zhong L, Li J, Tran K, Van Vliet K, Ren L, Su Q, He R, Goetzmann JE, Flotte TR, Agbandje-McKenna M, Gao G. A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates. Molecular Therapy. Methods & Clinical Development. 9: 234-246. PMID 29766031 DOI: 10.1016/J.Omtm.2018.03.004  0.36
2018 Smith JK, Agbandje-McKenna M. Creating an arsenal of Adeno-associated virus (AAV) gene delivery stealth vehicles. Plos Pathogens. 14: e1006929. PMID 29723270 DOI: 10.1371/Journal.Ppat.1006929  0.479
2018 Bennett AD, Wong K, Lewis J, Tseng YS, Smith JK, Chipman P, McKenna R, Samulski RJ, Kleinschmidt J, Agbandje-McKenna M. AAV6 K531 serves a dual function in selective receptor and antibody ADK6 recognition. Virology. 518: 369-376. PMID 29604478 DOI: 10.1016/J.Virol.2018.03.007  0.585
2018 Marr M, D'Abramo A, Pittman N, Agbandje-McKenna M, Cotmore SF, Tattersall P. Optimizing the Targeting of Mouse Parvovirus 1 to Murine Melanoma Selects for Recombinant Genomes and Novel Mutations in the Viral Capsid Gene. Viruses. 10. PMID 29385689 DOI: 10.3390/V10020054  0.416
2018 Ilyas M, Mietzsch M, Kailasan S, Väisänen E, Luo M, Chipman P, Smith JK, Kurian J, Sousa D, McKenna R, Söderlund-Venermo M, Agbandje-McKenna M. Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy. Viruses. 10. PMID 29300333 DOI: 10.3390/V10010022  0.81
2018 Mietzsch M, Luo M, Yu JC, Kailasan S, Ilyas M, Chipman P, Sousa D, Soderlund-Venermo M, McKenna R, Agbandje-McKenna M. Structural Characterization of Emerging Pathogenic Human Parvoviruses Microscopy and Microanalysis. 24: 1214-1215. DOI: 10.1017/S1431927618006554  0.768
2017 Pittman N, Misseldine A, Geilen L, Halder S, Smith JK, Kurian J, Chipman P, Janssen M, Mckenna R, Baker TS, D'Abramo A, Cotmore S, Tattersall P, Agbandje-McKenna M. Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction. Viruses. 9. PMID 29084163 DOI: 10.3390/V9110321  0.823
2017 Mietzsch M, Agbandje-McKenna M. The Good That Viruses Do. Annual Review of Virology. 4: iii-v. PMID 28961414 DOI: 10.1146/Annurev-Vi-04-071217-100011  0.326
2017 Kanaan NM, Sellnow RC, Boye SL, Coberly B, Bennett A, Agbandje-McKenna M, Sortwell CE, Hauswirth WW, Boye SE, Manfredsson FP. Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS. Molecular Therapy. Nucleic Acids. 8: 184-197. PMID 28918020 DOI: 10.1016/J.Omtn.2017.06.011  0.368
2017 Kondratov O, Marsic D, Crosson SM, Mendez-Gomez HR, Moskalenko O, Mietzsch M, Heilbronn R, Allison JR, Green KB, Agbandje-McKenna M, Zolotukhin S. Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28890324 DOI: 10.1016/J.Ymthe.2017.08.003  0.407
2017 Bennett A, Patel S, Mietzsch M, Jose A, Lins-Austin B, Yu JC, Bothner B, McKenna R, Agbandje-McKenna M. Thermal Stability as a Determinant of AAV Serotype Identity. Molecular Therapy. Methods & Clinical Development. 6: 171-182. PMID 28828392 DOI: 10.1016/J.Omtm.2017.07.003  0.528
2017 Tse LV, Klinc KA, Madigan VJ, Castellanos Rivera RM, Wells LF, Havlik LP, Smith JK, Agbandje-McKenna M, Asokan A. Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion. Proceedings of the National Academy of Sciences of the United States of America. PMID 28559317 DOI: 10.1073/Pnas.1704766114  0.423
2017 Mietzsch M, Kailasan S, Garrison J, Ilyas M, Chipman P, Kantola K, Janssen ME, Spear J, Sousa D, McKenna R, Brown K, Söderlund-Venermo M, Baker T, Agbandje-McKenna M. Structural insights into emerging pediatric pathogens human bocaparvoviruses. Journal of Virology. PMID 28331084 DOI: 10.1128/Jvi.00261-17  0.806
2017 Mietzsch M, Hering H, Hammer EM, Agbandje-McKenna M, Zolotukhin S, Heilbronn R. OneBac 2.0: Sf9 Cell Lines for Production of AAV1, AAV2 and AAV8 Vectors with Minimal Encapsidation of Foreign DNA. Human Gene Therapy Methods. PMID 28125901 DOI: 10.1089/Hgtb.2016.164  0.361
2017 Bennett A, Mietzsch M, Agbandje-McKenna M. Understanding capsid assembly and genome packaging for adeno-associated viruses Future Virology. 12: 283-297. DOI: 10.2217/Fvl-2017-0011  0.383
2017 Kurian JJ, Bennett A, Hull J, Janssen M, Baker T, McKenna R, Agbandje-McKenna M. Characterization of pH-dependent structural changes in adeno-associated virus by cryo-electron microscopy and three-dimensional image reconstruction Acta Crystallographica Section a Foundations and Advances. 73: a59-a59. DOI: 10.1107/S010876731709941X  0.529
2017 Mietzsch M, Vliet Kv, Lins-Austin B, Yu C, Janssen ME, Bröcker F, Kaplonek P, Cardone G, McKenna R, Crystal R, Wilson J, Baker T, Seeberger PH, Heilbronn R, Agbandje-McKenna M. Analysis of the AAVrh. 10 Capsid Structure and Its Antigenic and Receptor Interactions Molecular Therapy. 25: 335-335. DOI: 10.1016/J.Ymthe.2017.04.025  0.515
2016 Callaway HM, Feng KH, Lee DW, Allison AB, Pinard M, McKenna R, Agbandje-McKenna M, Hafenstein S, Parrish CR. Parvovirus capsid structures required for infection: mutations controlling receptor recognition and protease cleavages. Journal of Virology. PMID 27847360 DOI: 10.1128/Jvi.01871-16  0.741
2016 Drouin LM, Lins B, Janssen M, Bennett A, Chipman P, McKenna R, Chen W, Muzyczka N, Cardone G, Baker TS, Agbandje-McKenna M. Cryo-electron microscopy reconstruction and stability studies of Wild-Type and R432A Variant of AAV2 Reveals Capsid Structural Stability is a Major Factor in Genome Packaging. Journal of Virology. PMID 27440903 DOI: 10.1128/Jvi.00575-16  0.573
2016 Mahon BP, Bhatt A, Socorro L, Driscoll JM, Okoh C, Lomelino CL, Mboge MY, Kurian JJ, Tu C, Agbandje-McKenna M, Frost SC, McKenna R. Structure of carbonic anhydrase IX is adapted for low pH catalysis. Biochemistry. PMID 27439028 DOI: 10.1021/Acs.Biochem.6B00243  0.514
2016 Tseng YS, Vliet KV, Rao L, McKenna R, Byrne BJ, Asokan A, Agbandje-McKenna M. Generation and characterization of anti-AAV8 and anti-AAV9 monoclonal antibodies. Journal of Virological Methods. PMID 27424005 DOI: 10.1016/J.Jviromet.2016.07.009  0.553
2016 Pinard MA, Kurian JJ, Aggarwal M, Agbandje-McKenna M, McKenna R. Cryoannealing-induced space-group transition of crystals of the carbonic anhydrase psCA3. Acta Crystallographica. Section F, Structural Biology Communications. 72: 573-7. PMID 27380376 DOI: 10.1107/S2053230X16009286  0.725
2016 Smith RH, Hallwirth CV, Westerman M, Hetherington NA, Tseng YS, Cecchini S, Virag T, Ziegler ML, Rogozin IB, Koonin EV, Agbandje-McKenna M, Kotin RM, Alexander IE. Germline viral "fossils" guide in silico reconstruction of a mid-Cenozoic era marsupial adeno-associated virus. Scientific Reports. 6: 28965. PMID 27377618 DOI: 10.1038/Srep28965  0.382
2016 Aydemir F, Salganik M, Resztak J, Singh J, Bennett A, Agbandje-McKenna M, Muzyczka N. Mutants at the 2-fold interface of AAV2 structural proteins suggest a role in viral transcription for AAV capsids. Journal of Virology. PMID 27252527 DOI: 10.1128/Jvi.00493-16  0.407
2016 Huang LY, Patel A, Ng R, Miller EB, Halder S, McKenna R, Asokan A, Agbandje-McKenna M. Characterization of the Adeno-associated virus 1 and 6 sialic acid binding site. Journal of Virology. PMID 26962225 DOI: 10.1128/Jvi.00161-16  0.828
2016 Kailasan S, Garrison J, Ilyas M, Chipman P, McKenna R, Kantola K, Söderlund-Venermo M, Kučinskaitė-Kodzė I, Žvirblienė A, Agbandje-McKenna M. Mapping Antigenic Epitopes on the Human Bocavirus Capsid. Journal of Virology. 90: 4670-80. PMID 26912619 DOI: 10.1128/Jvi.02998-15  0.776
2016 Boye SL, Bennett A, Scalabrino ML, McCullough KT, Van Vliet K, Choudhury S, Ruan Q, Peterson J, Agbandje-McKenna M, Boye SE. The Impact of Heparan Sulfate Binding on Transduction of Retina by rAAV Vectors. Journal of Virology. PMID 26865709 DOI: 10.1128/Jvi.00200-16  0.357
2016 Mahon BP, Kurian JJ, Lomelino CL, Smith IR, Socorro L, Bennett A, Hendon AM, Chipman P, Savin DA, Agbandje-McKenna M, McKenna R. Microbatch Mixing: “Shaken not Stirred”, a Method for Macromolecular Microcrystal Production for Serial Crystallography Crystal Growth & Design. 16: 6214-6221. DOI: 10.1021/Acs.Cgd.6B00643  0.522
2016 Drouin LM, Lins B, Janssen M, Bennett A, Chipman PR, McKenna R, Chen W, Muzyczka N, Cardone G, Baker TS, Agbandje-McKenna M. Structural Rearrangements in R432A Variant of AAV2 Affect Genome Packaging Microscopy and Microanalysis. 22: 1134-1135. DOI: 10.1017/S1431927616006516  0.453
2016 Huang L, Patel A, Ng R, Miller EB, Halder S, McKenna R, Asokan A, Agbandje-McKenna M. 727. Characterizing the Adeno-Associated Virus 1 Sialic Receptor Binding Site and Its Overlap with Antigenic Epitopes Molecular Therapy. 24: S287. DOI: 10.1016/S1525-0016(16)33535-3  0.827
2016 Hallwirth CV, Smith RH, Westerman M, Hetherington NA, Tseng Y, Cecchini S, Virag T, Ziegler M, Rogozin IB, Koonin EV, Agbandje-McKenna M, Alexander IE, Kotin RM. 541. Use of Endogenous Viral Elements to Deduce the Sequence of an Ancient Adeno-Associated Virus That Circulated Amongst Australian Marsupials ~30 Million Years Ago Molecular Therapy. 24: S216. DOI: 10.1016/S1525-0016(16)33349-4  0.381
2016 Smith JK, Banala V, Mietzsch M, Chipman P, Agbandje-McKenna M. 294. Characterizing AAV CaptureSelect Affinity Ligand Interactions Molecular Therapy. 24: S118. DOI: 10.1016/S1525-0016(16)33103-3  0.443
2016 Henckaerts E, Tordo J, Palomar N, Rahman J, Aldrin-Kirk P, Basche M, Bennett A, O'Leary C, Ali R, Agbandje-McKenna M, Bigger B, Rahim AA, Björklund T, Waddington S, Linden RM. 256. A Novel Rationally Designed AAV Capsid Yields a Potent Neurotropic Gene Therapy Vector Molecular Therapy. 24: S101. DOI: 10.1016/S1525-0016(16)33065-9  0.381
2015 Kailasan S, Agbandje-McKenna M, Parrish CR. Parvovirus Family Conundrum: What Makes a Killer? Annual Review of Virology. 2: 425-50. PMID 26958923 DOI: 10.1146/Annurev-Virology-100114-055150  0.75
2015 Halder S, Van Vliet K, Smith JK, Duong TT, McKenna R, Wilson JM, Agbandje-McKenna M. Structure of neurotropic adeno-associated virus AAVrh.8. Journal of Structural Biology. PMID 26334681 DOI: 10.1016/J.Jsb.2015.08.017  0.843
2015 Díaz-Torres NA, Mahon BP, Boone CD, Pinard MA, Tu C, Ng R, Agbandje-McKenna M, Silverman D, Scott K, McKenna R. Structural and biophysical characterization of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration. Acta Crystallographica. Section D, Biological Crystallography. 71: 1745-56. PMID 26249355 DOI: 10.1107/S1399004715012183  0.467
2015 Li C, Wu S, Albright B, Hirsch M, Li W, Tseng YS, Agbandje-McKenna M, McPhee S, Asokan A, Samulski RJ. Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26220272 DOI: 10.1038/Mt.2015.134  0.375
2015 Kailasan S, Halder S, Gurda B, Bladek H, Chipman PR, McKenna R, Brown K, Agbandje-McKenna M. Structure of an enteric pathogen, bovine parvovirus. Journal of Virology. 89: 2603-14. PMID 25520501 DOI: 10.1128/Jvi.03157-14  0.813
2015 Tseng YS, Gurda BL, Chipman P, McKenna R, Afione S, Chiorini JA, Muzyczka N, Olson NH, Baker TS, Kleinschmidt J, Agbandje-McKenna M. Adeno-associated virus serotype 1 (AAV1)- and AAV5-antibody complex structures reveal evolutionary commonalities in parvovirus antigenic reactivity. Journal of Virology. 89: 1794-808. PMID 25410874 DOI: 10.1128/Jvi.02710-14  0.801
2015 Afione S, DiMattia MA, Halder S, Di Pasquale G, Agbandje-McKenna M, Chiorini JA. Identification and mutagenesis of the adeno-associated virus 5 sialic acid binding region. Journal of Virology. 89: 1660-72. PMID 25410855 DOI: 10.1128/Jvi.02503-14  0.806
2015 Nolasco D, Van Vliet K, Markusic D, Ling C, Huang L, Agbandje-McKenna M, Srivastava A, Aslanidi G. 315. Optimization of the Capsid of Recombinant Adeno-Associated Virus 6 (AAV6) Vectors for Liver-, and Muscle-Directed Gene Therapy Molecular Therapy. 23: S127. DOI: 10.1016/S1525-0016(16)33924-7  0.372
2015 Boerner K, Kienle E, Sacher A, Huang L, Bechtle M, Wiedtke E, Bayer P, Kräusslich H, Agbandje-McKenna M, Grimm D. 307. Rational Development of 12 Different AAV Serotypes as Scaffolds for Peptide Display Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33916-8  0.322
2015 Albright BH, Madigan V, Rao L, Chiorini JA, Agbandje-McKenna M, Asokan A. 302. Combinatorial Engineering of a Receptor Footprint on AAV Serotype 4 Yields Novel Vectors Molecular Therapy. 23: S122. DOI: 10.1016/S1525-0016(16)33911-9  0.398
2015 Afione S, DiMattia MA, Halder S, Di Pasquale G, Agbandje-McKenna M, Chiorini J. 91. Identification and Mutagenesis of the AAV5 Sialic Acid Binding Region Molecular Therapy. 23: S39. DOI: 10.1016/S1525-0016(16)33696-6  0.796
2014 Potter M, Lins B, Mietzsch M, Heilbronn R, Van Vliet K, Chipman P, Agbandje-McKenna M, Cleaver BD, Clément N, Byrne BJ, Zolotukhin S. A simplified purification protocol for recombinant adeno-associated virus vectors. Molecular Therapy. Methods & Clinical Development. 1: 14034. PMID 26015974 DOI: 10.1038/Mtm.2014.34  0.357
2014 Bird SW, Kirkegaard K, Agbandje-McKenna M, Freed EO. The ins and outs of viral infection: keystone meeting review. Viruses. 6: 3652-62. PMID 25256395 DOI: 10.3390/V6093652  0.379
2014 Marsic D, Govindasamy L, Currlin S, Markusic DM, Tseng YS, Herzog RW, Agbandje-McKenna M, Zolotukhin S. Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1900-9. PMID 25048217 DOI: 10.1038/Mt.2014.139  0.399
2014 Huang LY, Halder S, Agbandje-McKenna M. Parvovirus glycan interactions. Current Opinion in Virology. 7: 108-18. PMID 25047752 DOI: 10.1016/J.Coviro.2014.05.007  0.789
2014 Smith LJ, Ul-Hasan T, Carvaines SK, Van Vliet K, Yang E, Wong KK, Agbandje-McKenna M, Chatterjee S. Gene transfer properties and structural modeling of human stem cell-derived AAV. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1625-34. PMID 24925207 DOI: 10.1038/Mt.2014.107  0.311
2014 Judd J, Ho ML, Tiwari A, Gomez EJ, Dempsey C, Van Vliet K, Igoshin OA, Silberg JJ, Agbandje-McKenna M, Suh J. Tunable protease-activatable virus nanonodes. Acs Nano. 8: 4740-6. PMID 24796495 DOI: 10.1021/Nn500550Q  0.393
2014 Snijder J, van de Waterbeemd M, Damoc E, Denisov E, Grinfeld D, Bennett A, Agbandje-McKenna M, Makarov A, Heck AJ. Defining the stoichiometry and cargo load of viral and bacterial nanoparticles by Orbitrap mass spectrometry. Journal of the American Chemical Society. 136: 7295-9. PMID 24787140 DOI: 10.1021/Ja502616Y  0.305
2014 Mikals K, Nam HJ, Van Vliet K, Vandenberghe LH, Mays LE, McKenna R, Wilson JM, Agbandje-McKenna M. The structure of AAVrh32.33, a novel gene delivery vector. Journal of Structural Biology. 186: 308-17. PMID 24704217 DOI: 10.1016/J.Jsb.2014.03.020  0.61
2014 Hopkins M, Kailasan S, Cohen A, Roux S, Tucker KP, Shevenell A, Agbandje-McKenna M, Breitbart M. Diversity of environmental single-stranded DNA phages revealed by PCR amplification of the partial major capsid protein. The Isme Journal. 8: 2093-103. PMID 24694711 DOI: 10.1038/Ismej.2014.43  0.752
2014 Tseng YS, Agbandje-McKenna M. Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery Vectors. Frontiers in Immunology. 5: 9. PMID 24523720 DOI: 10.3389/Fimmu.2014.00009  0.408
2014 Halder S, Cotmore S, Heimburg-Molinaro J, Smith DF, Cummings RD, Chen X, Trollope AJ, North SJ, Haslam SM, Dell A, Tattersall P, McKenna R, Agbandje-McKenna M. Profiling of glycan receptors for minute virus of mice in permissive cell lines towards understanding the mechanism of cell recognition. Plos One. 9: e86909. PMID 24475195 DOI: 10.1371/Journal.Pone.0086909  0.806
2014 Mietzsch M, Grasse S, Zurawski C, Weger S, Bennett A, Agbandje-McKenna M, Muzyczka N, Zolotukhin S, Heilbronn R. OneBac: platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy. Human Gene Therapy. 25: 212-22. PMID 24299301 DOI: 10.1089/Hum.2013.184  0.352
2014 Cotmore SF, Agbandje-McKenna M, Chiorini JA, Mukha DV, Pintel DJ, Qiu J, Soderlund-Venermo M, Tattersall P, Tijssen P, Gatherer D, Davison AJ. The family Parvoviridae. Archives of Virology. 159: 1239-47. PMID 24212889 DOI: 10.1007/S00705-013-1914-1  0.348
2014 Salganik M, Aydemir F, Nam HJ, McKenna R, Agbandje-McKenna M, Muzyczka N. Adeno-associated virus capsid proteins may play a role in transcription and second-strand synthesis of recombinant genomes. Journal of Virology. 88: 1071-9. PMID 24198419 DOI: 10.1128/Jvi.02093-13  0.531
2014 Lins B, Agbandje-McKenna M. Nonenveloped capsid: mechanisms of viral entry Future Virology. 9: 1105-1121. DOI: 10.2217/Fvl.14.82  0.362
2013 Drouin LM, Agbandje-McKenna M. Adeno-associated virus structural biology as a tool in vector development. Future Virology. 8: 1183-1199. PMID 24533032 DOI: 10.2217/Fvl.13.112  0.448
2013 Tellez J, Van Vliet K, Tseng YS, Finn JD, Tschernia N, Almeida-Porada G, Arruda VR, Agbandje-McKenna M, Porada CD. Characterization of naturally-occurring humoral immunity to AAV in sheep. Plos One. 8: e75142. PMID 24086458 DOI: 10.1371/Journal.Pone.0075142  0.404
2013 Rayaprolu V, Kruse S, Kant R, Venkatakrishnan B, Movahed N, Brooke D, Lins B, Bennett A, Potter T, McKenna R, Agbandje-McKenna M, Bothner B. Comparative analysis of adeno-associated virus capsid stability and dynamics. Journal of Virology. 87: 13150-60. PMID 24067976 DOI: 10.1128/Jvi.01415-13  0.585
2013 Tartaglia LJ, Bennett A, Plattner AS, Muzyczka N, Ling C, Srivastava A, Agbandje-McKenna M. Molecular cloning, overexpression, and an efficient one-step purification of α5β1 integrin. Protein Expression and Purification. 92: 21-8. PMID 23993979 DOI: 10.1016/J.Pep.2013.08.013  0.347
2013 Shen S, Horowitz ED, Troupes AN, Brown SM, Pulicherla N, Samulski RJ, Agbandje-McKenna M, Asokan A. Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency. The Journal of Biological Chemistry. 288: 28814-23. PMID 23940044 DOI: 10.1074/Jbc.M113.482380  0.386
2013 Govindasamy L, DiMattia MA, Gurda BL, Halder S, McKenna R, Chiorini JA, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structural insights into adeno-associated virus serotype 5. Journal of Virology. 87: 11187-99. PMID 23926356 DOI: 10.1128/Jvi.00867-13  0.833
2013 Gurda BL, DiMattia MA, Miller EB, Bennett A, McKenna R, Weichert WS, Nelson CD, Chen WJ, Muzyczka N, Olson NH, Sinkovits RS, Chiorini JA, Zolotutkhin S, Kozyreva OG, Samulski RJ, ... ... Agbandje-McKenna M, et al. Capsid antibodies to different adeno-associated virus serotypes bind common regions. Journal of Virology. 87: 9111-24. PMID 23760240 DOI: 10.1128/Jvi.00622-13  0.787
2013 Mays LE, Wang L, Tenney R, Bell P, Nam HJ, Lin J, Gurda B, Van Vliet K, Mikals K, Agbandje-McKenna M, Wilson JM. Mapping the structural determinants responsible for enhanced T cell activation to the immunogenic adeno-associated virus capsid from isolate rhesus 32.33. Journal of Virology. 87: 9473-85. PMID 23720715 DOI: 10.1128/Jvi.00596-13  0.733
2013 Kay CN, Ryals RC, Aslanidi GV, Min SH, Ruan Q, Sun J, Dyka FM, Kasuga D, Ayala AE, Van Vliet K, Agbandje-McKenna M, Hauswirth WW, Boye SL, Boye SE. Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors. Plos One. 8: e62097. PMID 23637972 DOI: 10.1371/Journal.Pone.0062097  0.326
2013 Tartaglia LJ, Bennett A, Woodhouse AG, Aydemir F, Muzyczka N, Agbandje-McKenna M. Construction, expression, and purification of recombinant αVβ5 integrin. Protein Expression and Purification. 89: 225-31. PMID 23583935 DOI: 10.1016/J.Pep.2013.04.002  0.303
2013 Aslanidi GV, Rivers AE, Ortiz L, Song L, Ling C, Govindasamy L, Van Vliet K, Tan M, Agbandje-McKenna M, Srivastava A. Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold? Plos One. 8: e59142. PMID 23527116 DOI: 10.1371/Journal.Pone.0059142  0.373
2013 Halder S, Nam HJ, Govindasamy L, Vogel M, Dinsart C, Salomé N, McKenna R, Agbandje-McKenna M. Structural characterization of H-1 parvovirus: comparison of infectious virions to empty capsids. Journal of Virology. 87: 5128-40. PMID 23449783 DOI: 10.1128/Jvi.03416-12  0.83
2013 Venkatakrishnan B, Yarbrough J, Domsic J, Bennett A, Bothner B, Kozyreva OG, Samulski RJ, Muzyczka N, McKenna R, Agbandje-McKenna M. Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking. Journal of Virology. 87: 4974-84. PMID 23427155 DOI: 10.1128/Jvi.02524-12  0.572
2012 Judd J, Wei F, Nguyen PQ, Tartaglia LJ, Agbandje-McKenna M, Silberg JJ, Suh J. Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity. Molecular Therapy. Nucleic Acids. 1: e54. PMID 23629029 DOI: 10.1038/Mtna.2012.46  0.379
2012 Halder S, Nam HJ, Govindasamy L, Vogel M, Dinsart C, Salomé N, McKenna R, Agbandje-McKenna M. Production, purification, crystallization and structure determination of H-1 Parvovirus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 1571-6. PMID 23192051 DOI: 10.1107/S1744309112045563  0.792
2012 Yu Y, Mishra S, Song X, Lasanajak Y, Bradley KC, Tappert MM, Air GM, Steinhauer DA, Halder S, Cotmore S, Tattersall P, Agbandje-McKenna M, Cummings RD, Smith DF. Functional glycomic analysis of human milk glycans reveals the presence of virus receptors and embryonic stem cell biomarkers. The Journal of Biological Chemistry. 287: 44784-99. PMID 23115247 DOI: 10.1074/Jbc.M112.425819  0.789
2012 Salganik M, Venkatakrishnan B, Bennett A, Lins B, Yarbrough J, Muzyczka N, Agbandje-McKenna M, McKenna R. Evidence for pH-dependent protease activity in the adeno-associated virus capsid. Journal of Virology. 86: 11877-85. PMID 22915820 DOI: 10.1128/Jvi.01717-12  0.532
2012 Raupp C, Naumer M, Müller OJ, Gurda BL, Agbandje-McKenna M, Kleinschmidt JA. The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing. Journal of Virology. 86: 9396-408. PMID 22718833 DOI: 10.1128/Jvi.00209-12  0.768
2012 Fisher Z, Boone CD, Biswas SM, Venkatakrishnan B, Aggarwal M, Tu C, Agbandje-McKenna M, Silverman D, McKenna R. Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II. Protein Engineering, Design & Selection : Peds. 25: 347-55. PMID 22691706 DOI: 10.1093/Protein/Gzs027  0.722
2012 Li C, Diprimio N, Bowles DE, Hirsch ML, Monahan PE, Asokan A, Rabinowitz J, Agbandje-McKenna M, Samulski RJ. Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles. Journal of Virology. 86: 7752-9. PMID 22593151 DOI: 10.1128/Jvi.00675-12  0.394
2012 Gurda BL, Raupp C, Popa-Wagner R, Naumer M, Olson NH, Ng R, McKenna R, Baker TS, Kleinschmidt JA, Agbandje-McKenna M. Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8. Journal of Virology. 86: 7739-51. PMID 22593150 DOI: 10.1128/Jvi.00218-12  0.811
2012 Venkatakrishnan B, Palii ML, Agbandje-McKenna M, McKenna R. Mining the protein data bank to differentiate error from structural variation in clustered static structures: an examination of HIV protease. Viruses. 4: 348-62. PMID 22590675 DOI: 10.3390/V4030348  0.52
2012 Bell CL, Gurda BL, Van Vliet K, Agbandje-McKenna M, Wilson JM. Identification of the galactose binding domain of the adeno-associated virus serotype 9 capsid. Journal of Virology. 86: 7326-33. PMID 22514350 DOI: 10.1128/Jvi.00448-12  0.743
2012 Aslanidi GV, Rivers AE, Ortiz L, Govindasamy L, Ling C, Jayandharan GR, Zolotukhin S, Agbandje-McKenna M, Srivastava A. High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors. Vaccine. 30: 3908-17. PMID 22497875 DOI: 10.1016/J.Vaccine.2012.03.079  0.371
2012 DiMattia MA, Nam HJ, Van Vliet K, Mitchell M, Bennett A, Gurda BL, McKenna R, Olson NH, Sinkovits RS, Potter M, Byrne BJ, Aslanidi G, Zolotukhin S, Muzyczka N, Baker TS, ... Agbandje-McKenna M, et al. Structural insight into the unique properties of adeno-associated virus serotype 9. Journal of Virology. 86: 6947-58. PMID 22496238 DOI: 10.1128/Jvi.07232-11  0.804
2012 Harbison CE, Weichert WS, Gurda BL, Chiorini JA, Agbandje-McKenna M, Parrish CR. Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5. The Journal of General Virology. 93: 347-55. PMID 22071509 DOI: 10.1099/Vir.0.035113-0  0.726
2012 Bowles DE, McPhee SW, Li C, Gray SJ, Samulski JJ, Camp AS, Li J, Wang B, Monahan PE, Rabinowitz JE, Grieger JC, Govindasamy L, Agbandje-McKenna M, Xiao X, Samulski RJ. Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 443-55. PMID 22068425 DOI: 10.1038/Mt.2011.237  0.363
2012 Halder S, Ng R, Agbandje-Mckenna M. Parvoviruses: Structure and infection Future Virology. 7: 253-278. DOI: 10.2217/Fvl.12.12  0.789
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Agbandje-McKenna M, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  0.734
2011 Agbandje-McKenna M, Kuhn R. Current opinion in virology: structural virology. Current Opinion in Virology. 1: 81-3. PMID 22440620 DOI: 10.1016/J.Coviro.2011.07.001  0.312
2011 Agbandje-McKenna M, Kleinschmidt J. AAV capsid structure and cell interactions. Methods in Molecular Biology (Clifton, N.J.). 807: 47-92. PMID 22034026 DOI: 10.1007/978-1-61779-370-7_3  0.495
2011 Nam HJ, Gurda BL, McKenna R, Potter M, Byrne B, Salganik M, Muzyczka N, Agbandje-McKenna M. Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. Journal of Virology. 85: 11791-9. PMID 21900159 DOI: 10.1128/Jvi.05305-11  0.781
2011 Bell CL, Vandenberghe LH, Bell P, Limberis MP, Gao GP, Van Vliet K, Agbandje-McKenna M, Wilson JM. The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice. The Journal of Clinical Investigation. 121: 2427-35. PMID 21576824 DOI: 10.1172/Jci57367  0.404
2011 Pulicherla N, Shen S, Yadav S, Debbink K, Govindasamy L, Agbandje-McKenna M, Asokan A. Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1070-8. PMID 21364538 DOI: 10.1038/Mt.2011.22  0.351
2011 Sippel KH, Venkatakrishnan B, Boehlein SK, Sankaran B, Quirit JG, Govindasamy L, Agbandje-McKenna M, Goodison S, Rosser CJ, McKenna R. Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein. Proteins. 79: 528-36. PMID 21117240 DOI: 10.1002/Prot.22900  0.532
2011 Petrs-Silva H, Dinculescu A, Li Q, Deng WT, Pang JJ, Min SH, Chiodo V, Neeley AW, Govindasamy L, Bennett A, Agbandje-McKenna M, Zhong L, Li B, Jayandharan GR, Srivastava A, et al. Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 293-301. PMID 21045809 DOI: 10.1038/Mt.2010.234  0.378
2011 H. Sippel K, Stander A, Tu C, Venkatakrishnan B, H. Robbins A, Agbandje-McKenna M, Joubert F, M. Joubert A, McKenna R. Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds Letters in Drug Design & Discovery. 8: 678-684. DOI: 10.2174/157018011796576105  0.421
2011 Aslanidi G, Rivers A, Ortiz L, Govindasamy L, Agbandje-McKenna M, Srivastava A. Abstract C240: Modification on the capsid of recombinant adeno-associated virus vectors (rAAV) leads to high-efficiency transduction of human monocyte-derived dendritic cells (moDCs). Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C240  0.385
2010 Sippel KH, Genis C, Govindasamy L, Agbandje-McKenna M, Kiddle JJ, Tripp BC, McKenna R. Synchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase II. The Journal of Physical Chemistry Letters. 1: 2898-2902. PMID 20976122 DOI: 10.1021/Jz100954H  0.487
2010 Ng R, Govindasamy L, Gurda BL, McKenna R, Kozyreva OG, Samulski RJ, Parent KN, Baker TS, Agbandje-McKenna M. Structural characterization of the dual glycan binding adeno-associated virus serotype 6. Journal of Virology. 84: 12945-57. PMID 20861247 DOI: 10.1128/Jvi.01235-10  0.807
2010 Robbins AH, Domsic JF, Agbandje-McKenna M, McKenna R. Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinic P2(1) with a doubled a axis. Acta Crystallographica. Section D, Biological Crystallography. 66: 950-2. PMID 20693695 DOI: 10.1107/S0907444910023723  0.504
2010 Majumder A, Govindasamy L, Magis A, Kiss R, Polgár T, Baskin R, Allan RW, Agbandje-McKenna M, Reuther GW, Keseru GM, Bisht KS, Sayeski PP. Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core. The Journal of Biological Chemistry. 285: 31399-407. PMID 20667821 DOI: 10.1074/Jbc.M110.168211  0.302
2010 Domsic JF, Williams W, Fisher SZ, Tu C, Agbandje-McKenna M, Silverman DN, McKenna R. Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II. Biochemistry. 49: 6394-9. PMID 20578724 DOI: 10.1021/Bi1007645  0.485
2010 Ling C, Lu Y, Kalsi JK, Jayandharan GR, Li B, Ma W, Cheng B, Gee SW, McGoogan KE, Govindasamy L, Zhong L, Agbandje-McKenna M, Srivastava A. Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3. Human Gene Therapy. 21: 1741-7. PMID 20545554 DOI: 10.1089/Hum.2010.075  0.359
2010 Robbins AH, Domsic JF, Agbandje-McKenna M, McKenna R. Structure of a monoclinic polymorph of human carbonic anhydrase II with a doubled a axis. Acta Crystallographica. Section D, Biological Crystallography. 66: 628-34. PMID 20445238 DOI: 10.1107/S0907444910006797  0.529
2010 Gurda BL, Parent KN, Bladek H, Sinkovits RS, DiMattia MA, Rence C, Castro A, McKenna R, Olson N, Brown K, Baker TS, Agbandje-McKenna M. Human bocavirus capsid structure: insights into the structural repertoire of the parvoviridae. Journal of Virology. 84: 5880-9. PMID 20375175 DOI: 10.1128/Jvi.02719-09  0.799
2010 Di Pasquale G, Kaludov N, Agbandje-McKenna M, Chiorini JA. BAAV transcytosis requires an interaction with beta-1-4 linked- glucosamine and gp96. Plos One. 5: e9336. PMID 20231878 DOI: 10.1371/Journal.Pone.0009336  0.357
2010 Robbins AH, Coman RM, Bracho-Sanchez E, Fernandez MA, Gilliland CT, Li M, Agbandje-McKenna M, Wlodawer A, Dunn BM, McKenna R. Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes. Acta Crystallographica. Section D, Biological Crystallography. 66: 233-42. PMID 20179334 DOI: 10.1107/S0907444909054298  0.523
2010 Hirsch ML, Agbandje-McKenna M, Samulski RJ. Little vector, big gene transduction: fragmented genome reassembly of adeno-associated virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 6-8. PMID 20048740 DOI: 10.1038/Mt.2009.280  0.414
2010 Asokan A, Conway JC, Phillips JL, Li C, Hegge J, Sinnott R, Yadav S, DiPrimio N, Nam HJ, Agbandje-McKenna M, McPhee S, Wolff J, Samulski RJ. Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle. Nature Biotechnology. 28: 79-82. PMID 20037580 DOI: 10.1038/Nbt.1599  0.372
2010 Avvaru BS, Kim CU, Sippel KH, Gruner SM, Agbandje-McKenna M, Silverman DN, McKenna R. A short, strong hydrogen bond in the active site of human carbonic anhydrase II. Biochemistry. 49: 249-51. PMID 20000378 DOI: 10.1021/Bi902007B  0.49
2009 Sippel KH, Robbins AH, Domsic J, Genis C, Agbandje-McKenna M, McKenna R. High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 992-5. PMID 19851004 DOI: 10.1107/S1744309109036665  0.507
2009 Vandenberghe LH, Breous E, Nam HJ, Gao G, Xiao R, Sandhu A, Johnston J, Debyser Z, Agbandje-McKenna M, Wilson JM. Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints. Gene Therapy. 16: 1416-28. PMID 19727141 DOI: 10.1038/Gt.2009.101  0.453
2009 Sippel KH, Boehlein SK, Sakai Y, Quirit JG, Agbandje-McKenna M, Rosser CJ, McKenna R. Cloning, expression, purification, crystallization and preliminary X-ray analysis of Mycoplasma genitalium protein MG289. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 910-2. PMID 19724130 DOI: 10.1107/S1744309109030565  0.508
2009 Li W, Zhang L, Johnson JS, Zhijian W, Grieger JC, Ping-Jie X, Drouin LM, Agbandje-McKenna M, Pickles RJ, Samulski RJ. Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2067-77. PMID 19603002 DOI: 10.1038/Mt.2009.155  0.333
2009 Avvaru BS, Busby SA, Chalmers MJ, Griffin PR, Venkatakrishnan B, Agbandje-McKenna M, Silverman DN, McKenna R. Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network. Biochemistry. 48: 7365-72. PMID 19583303 DOI: 10.1021/Bi9007512  0.488
2009 Mitchell M, Nam HJ, Carter A, McCall A, Rence C, Bennett A, Gurda B, McKenna R, Porter M, Sakai Y, Byrne BJ, Muzyczka N, Aslanidi G, Zolotukhin S, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 715-8. PMID 19574648 DOI: 10.1107/S1744309109021460  0.779
2009 Van Vliet K, Mohiuddin Y, McClung S, Blouin V, Rolling F, Moullier P, Agbandje-McKenna M, Snyder RO. Adeno-associated virus capsid serotype identification: Analytical methods development and application. Journal of Virological Methods. 159: 167-77. PMID 19447508 DOI: 10.1016/J.Jviromet.2009.03.020  0.338
2009 Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M, Wilson JM. Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins. Journal of Immunology (Baltimore, Md. : 1950). 182: 6051-60. PMID 19414756 DOI: 10.4049/Jimmunol.0803965  0.317
2009 Robbins AH, Dunn BM, Agbandje-McKenna M, McKenna R. Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank. Acta Crystallographica. Section D, Biological Crystallography. 65: 294-6. PMID 19237752 DOI: 10.1107/S0907444908041632  0.429
2009 Yang L, Jiang J, Drouin LM, Agbandje-McKenna M, Chen C, Qiao C, Pu D, Hu X, Wang DZ, Li J, Xiao X. A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection. Proceedings of the National Academy of Sciences of the United States of America. 106: 3946-51. PMID 19234115 DOI: 10.1073/Pnas.0813207106  0.324
2009 Sippel KH, Robbins AH, Reutzel R, Boehlein SK, Namiki K, Goodison S, Agbandje-McKenna M, Rosser CJ, McKenna R. Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis. Journal of Bacteriology. 191: 2585-92. PMID 19233924 DOI: 10.1128/Jb.01680-08  0.552
2009 Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R. Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties. Biochemistry. 48: 1322-31. PMID 19170619 DOI: 10.1021/Bi802035F  0.47
2009 Levy HC, Bowman VD, Govindasamy L, McKenna R, Nash K, Warrington K, Chen W, Muzyczka N, Yan X, Baker TS, Agbandje-McKenna M. Heparin binding induces conformational changes in Adeno-associated virus serotype 2. Journal of Structural Biology. 165: 146-56. PMID 19121398 DOI: 10.1016/J.Jsb.2008.12.002  0.821
2008 Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Eugene Redmond D, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-1260. PMID 28178482 DOI: 10.1038/Mt.2008.100  0.445
2008 Sippel KH, Robbins AH, Reutzel R, Domsic J, Boehlein SK, Govindasamy L, Agbandje-McKenna M, Rosser CJ, McKenna R. Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37. Acta Crystallographica. Section D, Biological Crystallography. 64: 1172-8. PMID 19020356 DOI: 10.1107/S0907444908030175  0.48
2008 Zhong L, Li B, Jayandharan G, Mah CS, Govindasamy L, Agbandje-McKenna M, Herzog RW, Weigel-Van Aken KA, Hobbs JA, Zolotukhin S, Muzyczka N, Srivastava A. Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression. Virology. 381: 194-202. PMID 18834608 DOI: 10.1016/J.Virol.2008.08.027  0.356
2008 Domsic JF, Avvaru BS, Kim CU, Gruner SM, Agbandje-McKenna M, Silverman DN, McKenna R. Entrapment of carbon dioxide in the active site of carbonic anhydrase II. The Journal of Biological Chemistry. 283: 30766-71. PMID 18768466 DOI: 10.1074/Jbc.M805353200  0.5
2008 Etingov I, Itah R, Mincberg M, Keren-Naus A, Nam HJ, Agbandje-McKenna M, Davis C. An extension of the Minute Virus of Mice tissue tropism. Virology. 379: 245-55. PMID 18684479 DOI: 10.1016/J.Virol.2008.06.042  0.347
2008 Peterson KE, Pourciau S, Du M, Lacasse R, Pathmajeyan M, Poulsen D, Agbandje-McKenna M, Wehrly K, Chesebro B. Neurovirulence of polytropic murine retrovirus is influenced by two separate regions on opposite sides of the envelope protein receptor binding domain. Journal of Virology. 82: 8906-10. PMID 18579597 DOI: 10.1128/Jvi.02134-07  0.413
2008 Schmidt M, Govindasamy L, Afione S, Kaludov N, Agbandje-McKenna M, Chiorini JA. Molecular characterization of the heparin-dependent transduction domain on the capsid of a novel adeno-associated virus isolate, AAV(VR-942). Journal of Virology. 82: 8911-6. PMID 18524816 DOI: 10.1128/Jvi.00672-08  0.43
2008 Zhong L, Li B, Mah CS, Govindasamy L, Agbandje-McKenna M, Cooper M, Herzog RW, Zolotukhin I, Warrington KH, Weigel-Van Aken KA, Hobbs JA, Zolotukhin S, Muzyczka N, Srivastava A. Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses. Proceedings of the National Academy of Sciences of the United States of America. 105: 7827-32. PMID 18511559 DOI: 10.1073/Pnas.0802866105  0.372
2008 Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-60. PMID 18500254 DOI: 10.1038/mt.2008.100  0.336
2008 Van Vliet KM, Blouin V, Brument N, Agbandje-McKenna M, Snyder RO. The role of the adeno-associated virus capsid in gene transfer. Methods in Molecular Biology (Clifton, N.J.). 437: 51-91. PMID 18369962 DOI: 10.1007/978-1-59745-210-6_2  0.466
2008 DiPrimio N, Asokan A, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Surface loop dynamics in adeno-associated virus capsid assembly. Journal of Virology. 82: 5178-89. PMID 18367523 DOI: 10.1128/Jvi.02721-07  0.419
2008 Barrese AA, Genis C, Fisher SZ, Orwenyo JN, Kumara MT, Dutta SK, Phillips E, Kiddle JJ, Tu C, Silverman DN, Govindasamy L, Agbandje-McKenna M, McKenna R, Tripp BC. Inhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural study. Biochemistry. 47: 3174-84. PMID 18266323 DOI: 10.1021/Bi702385K  0.48
2008 Clemente JC, Robbins A, Graña P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. Journal of Medicinal Chemistry. 51: 852-60. PMID 18215016 DOI: 10.1021/Jm701170F  0.479
2008 Andersen FF, Knudsen B, Oliveira CL, Frøhlich RF, Krüger D, Bungert J, Agbandje-McKenna M, McKenna R, Juul S, Veigaard C, Koch J, Rubinstein JL, Guldbrandtsen B, Hede MS, Karlsson G, et al. Assembly and structural analysis of a covalently closed nano-scale DNA cage. Nucleic Acids Research. 36: 1113-9. PMID 18096620 DOI: 10.1093/Nar/Gkm1124  0.509
2008 Bennett A, McKenna R, Agbandje-McKenna M. A Comparative Analysis of the Structural Architecture of ssDNA Viruses Computational and Mathematical Methods in Medicine. 9: 183-196. DOI: 10.1080/17486700802168247  0.574
2007 Quesada O, Gurda B, Govindasamy L, McKenna R, Kohlbrenner E, Aslanidi G, Zolotukhin S, Muzyczka N, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 1073-6. PMID 18084098 DOI: 10.1107/S1744309107060289  0.767
2007 Moose RE, Clemente JC, Jackson LR, Ngo M, Wooten K, Chang R, Bennett A, Chakraborty S, Yowell CA, Dame JB, Agbandje-McKenna M, Dunn BM. Analysis of binding interactions of pepsin inhibitor-3 to mammalian and malarial aspartic proteases. Biochemistry. 46: 14198-205. PMID 18004881 DOI: 10.1021/Bi7014844  0.354
2007 Nam HJ, Lane MD, Padron E, Gurda B, McKenna R, Kohlbrenner E, Aslanidi G, Byrne B, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structure of adeno-associated virus serotype 8, a gene therapy vector. Journal of Virology. 81: 12260-71. PMID 17728238 DOI: 10.1128/Jvi.01304-07  0.81
2007 Grieger JC, Johnson JS, Gurda-Whitaker B, Agbandje-McKenna M, Samulski RJ. Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions. Journal of Virology. 81: 7833-43. PMID 17507473 DOI: 10.1128/Jvi.00580-07  0.414
2007 Zhong L, Zhao W, Wu J, Li B, Zolotukhin S, Govindasamy L, Agbandje-McKenna M, Srivastava A. A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1323-30. PMID 17440440 DOI: 10.1038/Sj.Mt.6300170  0.333
2007 Fisher SZ, Tu C, Bhatt D, Govindasamy L, Agbandje-McKenna M, McKenna R, Silverman DN. Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II. Biochemistry. 46: 3803-13. PMID 17330962 DOI: 10.1021/Bi602620K  0.448
2007 Fisher SZ, Tu C, Bhatt D, Govindasamy L, Agbandje-McKenna M, McKenna R, Silverman DN. Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II. Biochemistry. 46: 3803-13. PMID 17330962 DOI: 10.1021/Bi602620K  0.448
2007 Fisher SZ, Maupin CM, Budayova-Spano M, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Voth GA, McKenna R. Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism. Biochemistry. 46: 2930-7. PMID 17319692 DOI: 10.1021/Bi062066Y  0.464
2006 Miller EB, Gurda-Whitaker B, Govindasamy L, McKenna R, Zolotukhin S, Muzyczka N, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1271-4. PMID 17142915 DOI: 10.1107/S1744309106048184  0.587
2006 Van Vliet K, Blouin V, Agbandje-McKenna M, Snyder RO. Proteolytic mapping of the adeno-associated virus capsid. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 809-21. PMID 17010669 DOI: 10.1016/J.Ymthe.2006.08.1222  0.492
2006 Van Vliet K, Blouin V, Agbandje-McKenna M, Snyder RO. Proteolytic mapping of the adeno-associated virus capsid. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 809-21. PMID 17010669 DOI: 10.1016/j.ymthe.2006.08.1222  0.392
2006 Govindasamy L, Padron E, McKenna R, Muzyczka N, Kaludov N, Chiorini JA, Agbandje-McKenna M. Structurally mapping the diverse phenotype of adeno-associated virus serotype 4. Journal of Virology. 80: 11556-70. PMID 16971437 DOI: 10.1128/Jvi.01536-06  0.66
2006 Wu Z, Asokan A, Grieger JC, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes. Journal of Virology. 80: 11393-7. PMID 16943302 DOI: 10.1128/Jvi.01288-06  0.433
2006 Wu Z, Miller E, Agbandje-McKenna M, Samulski RJ. Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6. Journal of Virology. 80: 9093-103. PMID 16940521 DOI: 10.1128/Jvi.00895-06  0.359
2006 Asokan A, Hamra JB, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry. Journal of Virology. 80: 8961-9. PMID 16940508 DOI: 10.1128/Jvi.00843-06  0.432
2006 Sitharam M, Agbandje-McKenna M. Modeling virus self-assembly pathways: avoiding dynamics using geometric constraint decomposition. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 13: 1232-65. PMID 16901239 DOI: 10.1089/Cmb.2006.13.1232  0.317
2006 Nam HJ, Gurda-Whitaker B, Wand YG, Ilaria S, McKenna R, Mehta P, Alvarez RA, Agbandje-McKenna M. Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation Journal of Biological Chemistry. 281: 25670-25677. PMID 16822863 DOI: 10.1074/Jbc.M604421200  0.586
2006 Fisher SZ, Govindasamy L, Boyle N, Agbandje-McKenna M, Silverman DN, Blackburn GM, McKenna R. X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 618-22. PMID 16820676 DOI: 10.1107/S1744309106020446  0.501
2006 Clemente JC, Coman RM, Thiaville MM, Janka LK, Jeung JA, Nukoolkarn S, Govindasamy L, Agbandje-McKenna M, McKenna R, Leelamanit W, Goodenow MM, Dunn BM. Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir. Biochemistry. 45: 5468-77. PMID 16634628 DOI: 10.1021/Bi051886S  0.479
2006 Fisher SZ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rajaniemi HJ, McKenna R. Structure of human salivary alpha-amylase crystallized in a C-centered monoclinic space group. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 88-93. PMID 16511271 DOI: 10.1107/S1744309105042491  0.532
2006 Budayova-Spano M, Fisher SZ, Dauvergne MT, Agbandje-McKenna M, Silverman DN, Myles DA, McKenna R. Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 6-9. PMID 16511248 DOI: 10.1107/S1744309105038248  0.52
2006 Clemente JC, Govindasamy L, Madabushi A, Fisher SZ, Moose RE, Yowell CA, Hidaka K, Kimura T, Hayashi Y, Kiso Y, Agbandje-McKenna M, Dame JB, Dunn BM, McKenna R. Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor. Acta Crystallographica. Section D, Biological Crystallography. 62: 246-52. PMID 16510971 DOI: 10.1107/S0907444905041260  0.5
2006 López-Bueno A, Rubio M, Bryant N, McKenna R, Agbandje-McKenna M, Almendral JM. Host-Selected Amino Acid Changes at the Sialic Acid Binding Pocket of the Parvovirus Capsid Modulate Cell Binding Affinity and Determine Virulence Journal of Virology. 80: 1563-1573. PMID 16415031 DOI: 10.1128/Jvi.80.3.1563-1573.2006  0.593
2006 Asokan A, Hamra JB, Agbandje-McKenna M, Samulski RJ. 7. Adeno-Associated Virus Type 2 (AAV2) Contains an Integrin alpha5beta1 Recognition Sequence Essential for Viral Cell Entry Molecular Therapy. 13: S3. DOI: 10.1016/J.Ymthe.2006.08.017  0.432
2005 DiMattia M, Govindasamy L, Levy HC, Gurda-Whitaker B, Kalina A, Kohlbrenner E, Chiorini JA, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 917-21. PMID 16511195 DOI: 10.1107/S1744309105028514  0.805
2005 Lane MD, Nam HJ, Padron E, Gurda-Whitaker B, Kohlbrenner E, Aslanidi G, Byrne B, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 558-61. PMID 16511095 DOI: 10.1107/S1744309105014132  0.59
2005 Madabushi A, Chakraborty S, Fisher SZ, Clemente JC, Yowell C, Agbandje-McKenna M, Dame JB, Dunn BM, McKenna R. Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 228-31. PMID 16511002 DOI: 10.1107/S1744309105001405  0.462
2005 Kontou M, Govindasamy L, Nam HJ, Bryant N, Llamas-Saiz AL, Foces-Foces C, Hernando E, Rubio MP, McKenna R, Almendral JM, Agbandje-McKenna M. Structural Determinants of Tissue Tropism and In Vivo Pathogenicity for the Parvovirus Minute Virus of Mice Journal of Virology. 79: 10931-10943. PMID 16103145 DOI: 10.1128/Jvi.79.17.10931-10943.2005  0.607
2005 Duda DM, Tu C, Fisher SZ, An H, Yoshioka C, Govindasamy L, Laipis PJ, Agbandje-McKenna M, Silverman DN, McKenna R. Human carbonic anhydrase III: structural and kinetic study of catalysis and proton transfer. Biochemistry. 44: 10046-53. PMID 16042381 DOI: 10.1021/Bi050610H  0.53
2005 Ketcham CM, Anai S, Reutzel R, Sheng S, Schuster SM, Brenes RB, Agbandje-McKenna M, McKenna R, Rosser CJ, Boehlein SK. p37 Induces tumor invasiveness. Molecular Cancer Therapeutics. 4: 1031-8. PMID 16020660 DOI: 10.1158/1535-7163.Mct-05-0040  0.505
2005 Padron E, Bowman V, Kaludov N, Govindasamy L, Levy H, Nick P, McKenna R, Muzyczka N, Chiorini JA, Baker TS, Agbandje-McKenna M. Structure of adeno-associated virus type 4. Journal of Virology. 79: 5047-58. PMID 15795290 DOI: 10.1128/Jvi.79.8.5047-5058.2005  0.84
2005 Beyer BB, Johnson JV, Chung AY, Li T, Madabushi A, Agbandje-McKenna M, McKenna R, Dame JB, Dunn BM. Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries. Biochemistry. 44: 1768-79. PMID 15697202 DOI: 10.1021/Bi047886U  0.467
2004 Govindasamy L, Pedersen B, Lian W, Kukar T, Gu Y, Jin S, Agbandje-McKenna M, Wu D, McKenna R. Structural insights and functional implications of choline acetyltransferase. Journal of Structural Biology. 148: 226-35. PMID 15477102 DOI: 10.1016/J.Jsb.2004.06.005  0.526
2004 Clemente JC, Moose RE, Hemrajani R, Whitford LR, Govindasamy L, Reutzel R, McKenna R, Agbandje-McKenna M, Goodenow MM, Dunn BM. Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease. Biochemistry. 43: 12141-51. PMID 15379553 DOI: 10.1021/bi049459m  0.488
2004 Casado CG, Ortiz GJ, Padron E, Bean SJ, McKenna R, Agbandje-McKenna M, Boulton MI. Isolation and characterization of subgenomic DNAs encapsidated in "single" T = 1 isometric particles of Maize streak virus Virology. 323: 164-171. PMID 15165828 DOI: 10.1016/J.Virol.2004.02.014  0.483
2004 Govindasamy L, Reutzel R, Agbandje-McKenna M, McKenna R. Structural determination of a partially hemihedrally twinned actin crystal. Acta Crystallographica Section D-Biological Crystallography. 60: 1040-1047. PMID 15159563 DOI: 10.1107/S0907444904006948  0.505
2004 Govindasamy L, Kukar T, Lian W, Pedersen B, Gu Y, Agbandje-McKenna M, Jin S, McKenna R, Wu D. Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase. Journal of Structural Biology. 146: 416-24. PMID 15099582 DOI: 10.1016/J.Jsb.2004.01.011  0.444
2004 Reutzel R, Yoshioka C, Govindasamy L, Yarmola EG, Agbandje-McKenna M, Bubb MR, McKenna R. Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer. Journal of Structural Biology. 146: 291-301. PMID 15099571 DOI: 10.1016/J.Jsb.2003.12.006  0.481
2004 Walters RW, Agbandje-McKenna M, Bowman VD, Moninger TO, Olson NH, Seiler M, Chiorini JA, Baker TS, Zabner J. Structure of adeno-associated virus serotype 5. Journal of Virology. 78: 3361-71. PMID 15016858 DOI: 10.1128/Jvi.78.7.3361-3371.2004  0.501
2004 Lian W, Gu Y, Pedersen B, Kukar T, Govindasamy L, Agbandje-McKenna M, Jin S, McKenna R, Wu D. Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase. Acta Crystallographica. Section D, Biological Crystallography. 60: 374-5. PMID 14747730 DOI: 10.1107/S090744490302818X  0.457
2003 Govindasamy L, Hueffer K, Parrish CR, Agbandje-McKenna M. Structures of host range-controlling regions of the capsids of canine and feline parvoviruses and mutants. Journal of Virology. 77: 12211-21. PMID 14581558 DOI: 10.1128/Jvi.77.22.12211-12221.2003  0.365
2003 Opie SR, Warrington KH, Agbandje-McKenna M, Zolotukhin S, Muzyczka N. Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding. Journal of Virology. 77: 6995-7006. PMID 12768018 DOI: 10.1128/Jvi.77.12.6995-7006.2003  0.305
2003 Kaludov N, Padron E, Govindasamy L, McKenna R, Chiorini JA, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 4 Virology. 306: 1-6. PMID 12620791 DOI: 10.1016/S0042-6822(02)00037-5  0.548
2003 Wu D, Govindasamy L, Lian W, Gu Y, Kukar T, Agbandje-McKenna M, McKenna R. Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer. The Journal of Biological Chemistry. 278: 13159-65. PMID 12562770 DOI: 10.1074/Jbc.M212356200  0.484
2003 Duda D, Govindasamy L, Agbandje-McKenna M, Tu C, Silverman DN, McKenna R. The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer. Acta Crystallographica. Section D, Biological Crystallography. 59: 93-104. PMID 12499545 DOI: 10.1107/S0907444902019455  0.526
2002 Reutzel R, Boehlein SK, Govindasamy L, Brenes RB, Agbandje-Mckenna M, Schuster SM, Mckenna R. Crystallization and preliminary X-ray analysis of the tumor metastasis factor p37. Acta Crystallographica Section D-Biological Crystallography. 58: 2141-2144. PMID 12454480 DOI: 10.1107/S0907444902015536  0.526
2002 Lian W, Govindasamy L, Gu Y, Kukar T, Agbandje-McKenna M, McKenna R, Wu D. Crystallization and preliminary X-ray crystallographic studies on recombinant human carnitine acetyltransferase. Acta Crystallographica. Section D, Biological Crystallography. 58: 1193-4. PMID 12077440 DOI: 10.1107/S0907444902005498  0.504
2002 Bubb MR, Govindasamy L, Yarmola EG, Vorobiev SM, Almo SC, Somasundaram T, Chapman MS, Agbandje-McKenna M, McKenna R. Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution. The Journal of Biological Chemistry. 277: 20999-1006. PMID 11932258 DOI: 10.1074/Jbc.M201371200  0.503
2002 Brentlinger KL, Hafenstein S, Novak CR, Fane BA, Borgon R, McKenna R, Agbandje-McKenna M. Microviridae, a family divided: isolation, characterization, and genome sequence of phiMH2K, a bacteriophage of the obligate intracellular parasitic bacterium Bdellovibrio bacteriovorus. Journal of Bacteriology. 184: 1089-94. PMID 11807069 DOI: 10.1128/Jb.184.4.1089-1094.2002  0.685
2001 Bloom ME, Best SM, Hayes SF, Wells RD, Wolfinbarger JB, McKenna R, Agbandje-McKenna M. Identification of aleutian mink disease parvovirus capsid sequences mediating antibody-dependent enhancement of infection, virus neutralization, and immune complex formation. Journal of Virology. 75: 11116-27. PMID 11602751 DOI: 10.1128/Jvi.75.22.11116-11127.2001  0.55
2001 Duda D, Tu C, Qian M, Laipis P, Agbandje-McKenna M, Silverman DN, McKenna R. Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II. Biochemistry. 40: 1741-8. PMID 11327835 DOI: 10.1021/Bi002295Z  0.491
2001 Duda D, Tu C, Silverman D, Kalb (Gilboa) A, Agbandje-McKenna M, McKenna R. Ultra-High Resolution X-Ray Diffraction From Crystals Of The Kinetic Mutant Of Human Carbonic Anhydrase Ii, His 64 Ala, And Its Complexes With Proton Acceptor Donors. Protein & Peptide Letters. 8: 63-67. DOI: 10.2174/0929866013409751  0.517
2000 Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, Flotte T, Muzyczka N. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. Journal of Virology. 74: 8635-47. PMID 10954565 DOI: 10.1128/Jvi.74.18.8635-8647.2000  0.416
2000 Lombardo E, Ramírez JC, Agbandje-McKenna M, Almendral JM. A Beta-Stranded Motif Drives Capsid Protein Oligomers of the Parvovirus Minute Virus of Mice into the Nucleus for Viral Assembly Journal of Virology. 74: 3804-3814. PMID 10729155 DOI: 10.1128/Jvi.74.8.3804-3814.2000  0.373
2000 Hernando E, Llamas-Saiz AL, Foces-Foces C, McKenna R, Portman I, Agbandje-McKenna M, Almendral JM. Biochemical and Physical Characterization of Parvovirus Minute Virus of Mice Virus-like Particles Virology. 267: 299-309. PMID 10662625 DOI: 10.1006/Viro.1999.0123  0.571
1999 McKenna R, Olson NH, Chipman PR, Baker TS, Booth TF, Christensen J, Aasted B, Fox JM, Bloom ME, Wolfinbarger JB, Agbandje-McKenna M. Three-dimensional structure of Aleutian mink disease parvovirus: implications for disease pathogenicity. Journal of Virology. 73: 6882-91. PMID 10400786 DOI: 10.1128/Jvi.73.8.6882-6891.1999  0.591
1998 Chipman PR, Agbandje-McKenna M, Renaudin J, Baker TS, McKenna R. Structural analysis of the spiroplasma virus, SpV4: Implications for evolutionary variation to obtain host diversity among the Microviridae Structure. 6: 135-145. PMID 9519405 DOI: 10.1016/S0969-2126(98)00016-1  0.627
1997 Bloom ME, Martin DA, Oie KL, Huhtanen ME, Costello F, Wolfinbarger JB, Hayes SF, Agbandje-McKenna M. Expression of Aleutian mink disease parvovirus capsid proteins in defined segments: localization of immunoreactive sites and neutralizing epitopes to specific regions. Journal of Virology. 71: 705-14. PMID 8985402 DOI: 10.1128/Jvi.71.1.705-714.1997  0.406
1997 Olson NH, Chipman PR, Bloom ME, McKenna R, Agbandje-McKenna M, Booth TF, Baker TS. Automated CCD Data Collection and 3D Reconstruction of Aleutian Mink Disease Parvovirus Microscopy and Microanalysis. 3: 1117-1118. DOI: 10.1017/S1431927600012472  0.423
1996 Chipman PR, Agbandje-Mckenna M, Kajigaya S, Brown KE, Young NS, Baker TS, Rossmann MG. Cryo-electron microscopy studies of empty capsids of human parvovirus B19 complexed with its cellular receptor Proceedings of the National Academy of Sciences of the United States of America. 93: 7502-7506. PMID 8755503 DOI: 10.1073/Pnas.93.15.7502  0.575
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