William B. Isaacs - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Pharmacology, Biochemistry, Molecular Biology, Oncology, Radiology

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Grindedal EM, Zucknick M, Stormorken A, Rønne E, Tandstad NM, Isaacs WB, Axcrona K, Mæhle L. Outcomes of 10 years of PSA screening for prostate cancer in Norwegian men with Lynch syndrome. The Prostate. PMID 38629217 DOI: 10.1002/pros.24711  0.475
2023 Dairo OO, DePaula Oliveira L, Schaffer E, Vidotto T, Mendes AAA, Lu J, Huynh SV, Hicks JL, Sowalsky AG, De Marzo AM, Joshu CE, Hanratty B, Sfanos KS, Isaacs WB, Haffner MC, et al. FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-Genomic Features of Prostate Cancer. Cancer Research Communications. PMID 38112617 DOI: 10.1158/2767-9764.CRC-23-0248  0.759
2023 Wang A, Shen J, Rodriguez AA, Saunders EJ, Chen F, Janivara R, Darst BF, Sheng X, Xu Y, Chou AJ, Benlloch S, Dadaev T, Brook MN, Plym A, Sahimi A, ... ... Isaacs WB, et al. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. Nature Genetics. PMID 37945903 DOI: 10.1038/s41588-023-01534-4  0.493
2023 Patel RA, Sayar E, Coleman I, Roudier MP, Hanratty B, Low JY, Jaiswal N, Ajkunic A, Dumpit R, Ercan C, Salama N, O'Brien VP, Isaacs WB, Epstein JI, De Marzo AM, et al. Characterization of HOXB13 expression patterns in localized and metastatic castration-resistant prostate cancer. The Journal of Pathology. PMID 37850574 DOI: 10.1002/path.6216  0.597
2023 Kanayama M, Chen Y, Rabizadeh D, Vera L, Lu C, Nielsen SM, Russell EM, Esplin ED, Wang H, Isaacs WB, Antonarakis ES, Luo J. Clinical and Functional Analyses of an African-ancestry Gain-of-function HOXB13 Variant Implicated in Aggressive Prostate Cancer. European Urology Oncology. PMID 37806842 DOI: 10.1016/j.euo.2023.09.012  0.518
2023 Lupold SE, Isaacs WB, Luo J. Aggravated Androgen Receptor Activity in Otherwise Indolent Prostate Cancer. European Urology. PMID 37635043 DOI: 10.1016/j.eururo.2023.08.006  0.772
2023 Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T, Brook MN, Hoffmann TJ, Muir K, Wan P, Le Marchand L, Wilkens L, Wang Y, ... ... Isaacs WB, et al. Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry. American Journal of Human Genetics. PMID 37311464 DOI: 10.1016/j.ajhg.2023.05.010  0.458
2023 Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T, Brook MN, Hoffmann TJ, Muir K, Wan P, Marchand LL, Wilkens L, Wang Y, ... ... Isaacs WB, et al. Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry. Medrxiv : the Preprint Server For Health Sciences. PMID 37292833 DOI: 10.1101/2023.05.12.23289860  0.457
2023 Sattari M, Kohvakka A, Moradi E, Rauhala H, Urhonen H, Isaacs WB, Nykter M, Murtola TJ, Tammela TLJ, Latonen L, Bova GS, Kesseli J, Visakorpi T. Identification of long noncoding RNAs with aberrant expression in prostate cancer metastases. Endocrine-Related Cancer. PMID 37140987 DOI: 10.1530/ERC-22-0247  0.458
2023 Chen F, Madduri RK, Rodriguez AA, Darst BF, Chou A, Sheng X, Wang A, Shen J, Saunders EJ, Rhie SK, Bensen JT, Ingles SA, Kittles RA, Strom SS, Rybicki BA, ... ... Isaacs WB, et al. Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry. European Urology. PMID 36872133 DOI: 10.1016/j.eururo.2023.01.022  0.563
2023 Vidotto T, Imada EL, Faisal F, Murali S, Mendes AA, Kaur H, Zheng S, Xu J, Schaeffer EM, Isaacs WB, Sfanos KS, Marchionni L, Lotan TL. Association of self-identified race and genetic ancestry with the immunogenomic landscape of primary prostate cancer. Jci Insight. 8. PMID 36752203 DOI: 10.1172/jci.insight.162409  0.723
2022 Wei J, Beebe-Dimmer J, Shi Z, Sample C, Yan G, Rifkin AS, Sadeghpour A, Gielzak M, Choi S, Moon D, Zheng SL, Helfand BT, Walsh PC, Xu J, Cooney KA, ... Isaacs WB, et al. Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestry. The Prostate. PMID 36567534 DOI: 10.1002/pros.24477  0.52
2022 Shi Z, Zhan J, Wei J, Ladson-Gary S, Wang CH, Hulick PJ, Zheng SL, Cooney KA, Isaacs WB, Helfand BT, Koelsch BL, Xu J. Reliability of Ancestry-specific Prostate Cancer Genetic Risk Score in Four Racial and Ethnic Populations. European Urology Open Science. 45: 23-30. PMID 36353656 DOI: 10.1016/j.euros.2022.09.001  0.393
2022 Glaser A, Shi Z, Wei J, Lanman NA, Ladson-Gary S, Vickman RE, Franco OE, Crawford SE, Lilly Zheng S, Hayward SW, Isaacs WB, Helfand BT, Xu J. Shared Inherited Genetics of Benign Prostatic Hyperplasia and Prostate Cancer. European Urology Open Science. 43: 54-61. PMID 36353071 DOI: 10.1016/j.euros.2022.07.004  0.585
2022 Pham MT, Gupta A, Gupta H, Vaghasia A, Skaist A, Garrison MA, Coulter JB, Haffner MC, Zheng SL, Xu J, DeStefano Shields C, Isaacs WB, Wheelan SJ, Nelson WG, Yegnasubramanian S. Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole Genome Sequencing. Molecular Cancer Research : McR. PMID 35452513 DOI: 10.1158/1541-7786.MCR-21-0683  0.367
2022 Xu J, Resurreccion WK, Shi Z, Wei J, Wang CH, Zheng SL, Hulick PJ, Ross AE, Pavlovich CP, Helfand BT, Isaacs WB. Inherited risk assessment and its clinical utility for predicting prostate cancer from diagnostic prostate biopsies. Prostate Cancer and Prostatic Diseases. PMID 35347252 DOI: 10.1038/s41391-021-00458-6  0.548
2022 de la Calle CM, Bhanji Y, Pavlovich CP, Isaacs WB. The role of genetic testing in prostate cancer screening, diagnosis, and treatment. Current Opinion in Oncology. PMID 35238838 DOI: 10.1097/CCO.0000000000000823  0.439
2022 Xu J, Shi Z, Wei J, Na R, Resurreccion WK, Wang CH, Sample C, Han M, Zheng SL, Cooney KA, Helfand BT, Isaacs WB. KLK3 germline mutation I179T complements DNA repair genes for predicting prostate cancer progression. Prostate Cancer and Prostatic Diseases. PMID 35149774 DOI: 10.1038/s41391-021-00466-6  0.422
2022 Nelson WG, Brawley OW, Isaacs WB, Platz EA, Yegnasubramanian S, Sfanos KS, Lotan TL, De Marzo AM. Health inequity drives disease biology to create disparities in prostate cancer outcomes. The Journal of Clinical Investigation. 132. PMID 35104804 DOI: 10.1172/JCI155031  0.769
2022 Darst BF, Hughley R, Pfennig A, Hazra U, Fan C, Wan P, Sheng X, Xia L, Andrews C, Chen F, Berndt SI, Kote-Jarai Z, Govindasami K, Bensen JT, Ingles SA, ... ... Isaacs WB, et al. A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry. European Urology. PMID 35031163 DOI: 10.1016/j.eururo.2021.12.023  0.553
2021 Na R, Wei J, Sample CJ, Gielzak M, Choi S, Cooney KA, Rabizadeh D, Walsh PC, Zheng LS, Xu J, Isaacs WB. The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients. British Journal of Cancer. PMID 34799695 DOI: 10.1038/s41416-021-01622-4  0.525
2021 Shi Z, Lu L, Resurreccion WK, Yang W, Wei J, Wang Q, Engelmann V, Zheng SL, Cooney KA, Isaacs WB, Helfand BT, Lu J, Xu J. Association of germline rare pathogenic mutations in guideline-recommended genes with prostate cancer progression: A meta-analysis. The Prostate. PMID 34674288 DOI: 10.1002/pros.24252  0.445
2021 Kaur HB, Vidotto T, Mendes AA, Salles DC, Isaacs WB, Antonarakis ES, Lotan TL. Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancer. Cancer Immunology, Immunotherapy : Cii. PMID 34533610 DOI: 10.1007/s00262-021-03050-y  0.379
2021 Jasu J, Tolonen T, Antonarakis ES, Beltran H, Halabi S, Eisenberger MA, Carducci MA, Loriot Y, Van der Eecken K, Lolkema M, Ryan CJ, Taavitsainen S, Gillessen S, Högnäs G, Talvitie T, ... ... Isaacs WB, et al. Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine. European Urology Open Science. 30: 47-62. PMID 34337548 DOI: 10.1016/j.euros.2021.05.011  0.53
2021 Wei J, Yang W, Shi Z, Lu L, Wang Q, Resurreccion WK, Engelmann V, Zheng SL, Hulick PJ, Cooney KA, Isaacs WB, Helfand BT, Lu J, Xu J. Observed evidence for guideline-recommended genes in predicting prostate cancer risk from a large population-based cohort. The Prostate. PMID 34254341 DOI: 10.1002/pros.24195  0.506
2021 Bhanji Y, Isaacs WB, Xu J, Cooney KA. Prostate Cancer Predisposition. The Urologic Clinics of North America. 48: 283-296. PMID 34210485 DOI: 10.1016/j.ucl.2021.03.001  0.496
2021 Xu J, Isaacs WB. Incorporation of Polygenic Risk Score into Guidelines for Inherited Risk Assessment for Prostate Cancer. European Urology. PMID 34024654 DOI: 10.1016/j.eururo.2021.04.043  0.432
2021 Zhu Y, Dalrymple SL, Coleman I, Zheng SL, Xu J, Hooper JE, Antonarakis ES, De Marzo AM, Meeker AK, Nelson PS, Isaacs WB, Denmeade SR, Luo J, Brennen WN, Isaacs JT. Correction: Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors. Oncogene. PMID 33958727 DOI: 10.1038/s41388-021-01805-6  0.66
2021 Xu J, Isaacs WB, Mamawala M, Shi Z, Landis P, Petkewicz J, Wei J, Wang CH, Resurreccion WK, Na R, Bhanji Y, Novakovic K, Walsh PC, Zheng SL, Helfand BT, et al. Association of prostate cancer polygenic risk score with number and laterality of tumor cores in active surveillance patients. The Prostate. PMID 33956350 DOI: 10.1002/pros.24140  0.505
2021 Brennen WN, Zhu Y, Coleman IM, Dalrymple SL, Antony L, Patel RA, Hanratty B, Chikarmane R, Meeker AK, Zheng SL, Hooper JE, Luo J, De Marzo AM, Corey E, Xu J, ... ... Isaacs WB, et al. Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer. Jci Insight. PMID 33724955 DOI: 10.1172/jci.insight.146827  0.696
2021 Eskra JN, Rabizadeh D, Zhang J, Isaacs WB, Luo J, Pavlovich CP. Specific Detection of Prostate Cancer Cells in Urine by RNA in Situ Hybridization. The Journal of Urology. 101097JU000000000000. PMID 33617332 DOI: 10.1097/JU.0000000000001691  0.57
2021 Zhu Y, Dalrymple SL, Coleman I, Zheng SL, Xu J, Hooper JE, Antonarakis ES, De Marzo AM, Meeker AK, Nelson PS, Isaacs WB, Denmeade SR, Luo J, Brennen WN, Isaacs JT. Correction to: Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors. Oncogene. PMID 33564077 DOI: 10.1038/s41388-021-01640-9  0.66
2021 Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA, Benlloch S, Dadaev T, Brook MN, Sahimi A, Hoffmann TJ, Takahashi A, Matsuda K, ... ... Isaacs WB, et al. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nature Genetics. PMID 33473200 DOI: 10.1038/s41588-021-00786-2  0.433
2021 Lotan TL, Kaur HB, Salles DC, Murali S, Schaeffer EM, Lanchbury JS, Isaacs WB, Brown R, Richardson AL, Cussenot O, Cancel-Tassin G, Timms KM, Antonarakis ES. Homologous recombination deficiency (HRD) score in germline BRCA2- versus ATM-altered prostate cancer. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 33462368 DOI: 10.1038/s41379-020-00731-4  0.445
2021 Karlsson Q, Brook MN, Dadaev T, Wakerell S, Saunders EJ, Muir K, Neal DE, Giles GG, MacInnis RJ, Thibodeau SN, McDonnell SK, Cannon-Albright L, Teixeira MR, Paulo P, Cardoso M, ... ... Isaacs WB, et al. Rare Germline Variants in ATM Predispose to Prostate Cancer: A PRACTICAL Consortium Study. European Urology Oncology. PMID 33436325 DOI: 10.1016/j.euo.2020.12.001  0.527
2021 Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA, Benlloch S, Dadaev T, Brook MN, Sahimi A, Hoffmann TJ, Takahashi A, Matsuda K, ... ... Isaacs WB, et al. Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nature Genetics. PMID 33398198 DOI: 10.1038/s41588-020-00748-0  0.476
2020 Black MH, Li S, LaDuca H, Lo MT, Chen J, Hoiness R, Gutierrez S, Tippin-Davis B, Lu HM, Gielzak M, Wiley K, Shi Z, Wei J, Zheng SL, Helfand BT, ... Isaacs W, et al. Validation of a prostate cancer polygenic risk score. The Prostate. 80: 1314-1321. PMID 33258481 DOI: 10.1002/Pros.24058  0.526
2020 Shi Z, Platz EA, Wei J, Na R, Fantus RJ, Wang CH, Eggener SE, Hulick PJ, Duggan D, Zheng SL, Cooney KA, Isaacs WB, Helfand BT, Xu J. Performance of Three Inherited Risk Measures for Predicting Prostate Cancer Incidence and Mortality: A Population-based Prospective Analysis. European Urology. PMID 33257031 DOI: 10.1016/j.eururo.2020.11.014  0.405
2020 Liu W, Zheng SL, Na R, Wei L, Sun J, Gallagher J, Wei J, Resurreccion WK, Ernst S, Sfanos KS, Isaacs WB, Xu J. Distinct Genomic Alterations in Prostate Tumors Derived from African American Men. Molecular Cancer Research : McR. PMID 33115829 DOI: 10.1158/1541-7786.MCR-20-0648  0.722
2020 Zhu Y, Dalrymple SL, Coleman I, Zheng SL, Xu J, Hooper JE, Antonarakis ES, De Marzo AM, Meeker AK, Nelson PS, Isaacs WB, Denmeade SR, Luo J, Brennen WN, Isaacs JT. Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors. Oncogene. PMID 32989253 DOI: 10.1038/s41388-020-01479-6  0.591
2020 Wei J, Shi Z, Na R, Wang CH, Resurreccion WK, Zheng SL, Hulick PJ, Cooney KA, Helfand BT, Isaacs WB, Xu J. Germline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank. British Journal of Cancer. PMID 32830201 DOI: 10.1038/S41416-020-01036-8  0.473
2020 Eskra JN, Rabizadeh D, Mangold L, Fabian E, Brennen WN, Yeater DB, Pienta KJ, Partin AW, Isaacs WB, Pavlovich CP, Luo J. A novel method for detection of exfoliated prostate cancer cells in urine by RNA in situ hybridization. Prostate Cancer and Prostatic Diseases. PMID 32820256 DOI: 10.1038/S41391-020-00272-6  0.588
2020 Liu W, Hou J, Petkewicz J, Na R, Wang CH, Sun J, Gallagher J, Bogachkov YY, Swenson L, Regner M, Resurreccion WK, Isaacs WB, Brendler CB, Crawford S, Zheng SL, et al. Feasibility and performance of a novel probe panel to detect somatic DNA copy number alterations in clinical specimens for predicting prostate cancer progression. The Prostate. PMID 32803894 DOI: 10.1002/Pros.24057  0.489
2020 Schaid DJ, McDonnell SK, FitzGerald LM, DeRycke L, Fogarty Z, Giles GG, MacInnis RJ, Southey MC, Nguyen-Dumont T, Cancel-Tassin G, Cussenot O, Whittemore AS, Sieh W, Ioannidis NM, Hsieh CL, ... ... Isaacs W, et al. Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer. European Urology. PMID 32800727 DOI: 10.1016/J.Eururo.2020.07.038  0.626
2020 Gundem G, Van Loo P, Kremeyer B, Alexandrov LB, Tubio JMC, Papaemmanuil E, Brewer DS, Kallio HML, Hägnäs G, Annala M, Kivinummi K, Goody V, Latimer C, O'Meara S, Dawson KJ, ... Isaacs W, et al. Author Correction: The evolutionary history of lethal metastatic prostate cancer. Nature. PMID 32728210 DOI: 10.1038/S41586-020-2581-5  0.587
2020 Kaur H, Salles DC, Murali S, Hicks JL, Nguyen M, Pritchard CC, De Marzo AM, Lanchbury JS, Trock BJ, Isaacs WB, Timms KM, Antonarakis ES, Lotan TL. Genomic and Clinical-Pathologic Characterization of -deficient Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32694154 DOI: 10.1158/1078-0432.Ccr-20-0764  0.63
2020 Hurwitz LM, Kulac I, Gumuskaya B, Baena Del Valle JA, Benedetti I, Pan F, Liu JO, Marrone MT, Arnold KB, Goodman PJ, Tangen CM, Lucia MS, Thompson IM, Drake CG, Isaacs WB, et al. Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 32581009 DOI: 10.1158/1940-6207.Capr-19-0450  0.568
2020 Giri VN, Knudsen KE, Kelly WK, Cheng HH, Cooney KA, Cookson MS, Dahut W, Weissman S, Soule HR, Petrylak DP, Dicker AP, AlDubayan SH, Toland AE, Pritchard CC, Pettaway CA, ... ... Isaacs WB, et al. Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2000046. PMID 32516092 DOI: 10.1200/Jco.20.00046  0.581
2020 Darst BF, Wan P, Sheng X, Bensen JT, Ingles SA, Rybicki BA, Nemesure B, John EM, Fowke JH, Stevens VL, Berndt SI, Huff CD, Strom SS, Park JY, Zheng W, ... ... Isaacs WB, et al. A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry. European Urology. PMID 32409115 DOI: 10.1016/J.Eururo.2020.04.060  0.507
2020 Lu C, Terbuch A, Dolling D, Yu J, Wang H, Chen Y, Fountain J, Bertan C, Sharp A, Carreira S, Isaacs WB, Antonarakis ES, De Bono JS, Luo J. Treatment with abiraterone and enzalutamide does not overcome poor outcome from metastatic castration-resistant prostate cancer in men with the germline homozygous HSD3B1 c.1245C genotype. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 32387417 DOI: 10.1016/J.Annonc.2020.04.473  0.532
2020 Wu Y, Yu H, Li S, Wiley K, Zheng SL, LaDuca H, Gielzak M, Na R, Sarver BAJ, Helfand BT, Walsh PC, Lotan TL, Cooney KA, Black MH, Xu J, ... Isaacs WB, et al. Rare Germline Pathogenic Mutations of DNA Repair Genes Are Most Strongly Associated with Grade Group 5 Prostate Cancer. European Urology Oncology. PMID 31948886 DOI: 10.1016/J.Euo.2019.12.003  0.538
2020 Darst BF, Bensen JT, Ingles SA, Rybicki BA, Nemesure B, John EM, Fowke JH, Stevens VL, Berndt SI, Huff CD, Park JY, Zheng W, Ostrander EA, Srivastava S, Carpten J, ... ... Isaacs WB, et al. Abstract 3517: A germline variant at 8q24 contributes to familial clustering of prostate cancer in men of African ancestry Epidemiology. DOI: 10.1158/1538-7445.Am2020-3517  0.554
2020 Wu Y, Yu H, Li S, Wiley K, Zheng S, LaDuca H, Gielzak M, Na R, Sarver B, Helfand* B, Walsh P, Lotan T, Cooney K, Black M, Xu J, ... Isaacs W, et al. PD52-04 RARE GERMLINE PATHOGENIC MUTATIONS OF DNA REPAIR GENES ARE MOST STRONGLY ASSOCIATED WITH GRADE GROUP 5 PROSTATE CANCER The Journal of Urology. 203: e1090-e1091. DOI: 10.1097/Ju.0000000000000954.04  0.492
2020 Wu Y, Wei J, Shi Z, Fantus R, Zheng S, Cooney K, Isaacs W, Helfand* B, Xu J. PD38-06 WHICH GERMLINE GENES SHOULD BE TESTED FOR ASSESSING PROSTATE CANCER RISK? RESULTS FROM A LARGE POPULATION OF UNSELECTED CASES AND CONTROLS FROM UK BIOBANK The Journal of Urology. 203: e803. DOI: 10.1097/Ju.0000000000000917.06  0.499
2019 Na R, Labbate C, Yu H, Shi Z, Fantus RJ, Wang CH, Andriole GL, Isaacs WB, Zheng SL, Helfand BT, Xu J. Single-Nucleotide Polymorphism-Based Genetic Risk Score and Patient Age at Prostate Cancer Diagnosis. Jama Network Open. 2: e1918145. PMID 31880795 DOI: 10.1001/jamanetworkopen.2019.18145  0.459
2019 Ledet EM, Antonarakis ES, Isaacs WB, Lotan TL, Pritchard C, Sartor AO. Germline BLM mutations and metastatic prostate cancer. The Prostate. PMID 31816118 DOI: 10.1002/Pros.23924  0.498
2019 Velho PI, Lim D, Wang H, Park JC, Kaur HB, Almutairi F, Carducci MA, Denmeade SR, Markowski MC, Isaacs WB, Antonarakis ES, Pritchard CC, Eisenberger MA, Lotan TL. Molecular Characterization and Clinical Outcomes of Primary Gleason Pattern 5 Prostate Cancer After Radical Prostatectomy. Jco Precision Oncology. 3. PMID 31650100 DOI: 10.1200/PO.19.00081  0.435
2019 Isaacs WB, Cooney KA, Xu J. Updated insights into genetic contribution to prostate cancer predisposition: focus on HOXB13. The Canadian Journal of Urology. 26: 12-13. PMID 31629417  0.584
2019 Porter CM, Haffner MC, Kulac I, Maynard JP, Baena-Del Valle JA, Isaacs WB, Yegnasubramanian S, De Marzo AM, Sfanos KS. Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis. The American Journal of Pathology. PMID 31499027 DOI: 10.1016/J.Ajpath.2019.07.016  0.771
2019 Xu J, Labbate CV, Isaacs WB, Helfand BT. Inherited risk assessment of prostate cancer: it takes three to do it right. Prostate Cancer and Prostatic Diseases. PMID 31417171 DOI: 10.1038/S41391-019-0165-Y  0.589
2019 Langston ME, Bhalla A, Alderete JF, Nevin RL, Pakpahan R, Hansen J, Elliott D, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Platz EA, Sutcliffe S. Trichomonas vaginalis infection and prostate-specific antigen concentration: Insights into prostate involvement and prostate disease risk. The Prostate. PMID 31376187 DOI: 10.1002/Pros.23886  0.613
2019 Zarif JC, Baena-Del Valle JA, Hicks JL, Heaphy CM, Vidal I, Luo J, Lotan TL, Hooper JE, Isaacs WB, Pienta KJ, De Marzo AM. Mannose Receptor-positive Macrophage Infiltration Correlates with Prostate Cancer Onset and Metastatic Castration-resistant Disease. European Urology Oncology. 2: 429-436. PMID 31277779 DOI: 10.1016/J.Euo.2018.09.014  0.532
2019 Isaacs WB, Xu J. Current progress and questions in germline genetics of prostate cancer. Asian Journal of Urology. 6: 3-9. PMID 30775244 DOI: 10.1016/J.Ajur.2018.10.001  0.514
2019 Ledet E, Antonarakis ES, Pritchard C, Isaacs WB, Sartor AO. Germline heterozygous BLM mutations and prostate cancer risk. Journal of Clinical Oncology. 37: 321-321. DOI: 10.1200/Jco.2019.37.7_Suppl.321  0.577
2019 Antonarakis ES, Kaur HB, Hicks J, Pritchard CC, De Marzo AM, Isaacs WB, Lotan TL. ATM loss in primary prostate cancer: Analysis of >1000 cases using a validated clinical-grade immunohistochemistry (IHC) assay. Journal of Clinical Oncology. 37: 5069-5069. DOI: 10.1200/Jco.2019.37.15_Suppl.5069  0.534
2019 Chia L, Zhu G, Gorbounov M, Xian L, Chisholm B, Heydarian M, Johng D, Isaacs WB, Reddy K, Resar LS. Abstract 2595: HMGA1 induces theHOXB13developmental gene to drive tumor progression in androgen receptor negative, castrate-resistant prostate cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2595  0.574
2019 Zarif JC, Valle JAB, Hicks JL, Heaphy CM, Vidal I, Luo J, Lotan TL, Hooper JE, Isaacs WB, Pienta KJ, Marzo AMD. Abstract 4582: Mannose receptor positive macrophage infiltrate correlates with prostate cancer onset and metastatic castration-resistant disease Cancer Research. 79: 4582-4582. DOI: 10.1158/1538-7445.Am2019-4582  0.609
2019 Labbate* C, Shi Z, Black MH, Li S, Laduca H, Wang C, Yu H, Helfand B, Isaacs W, Xu J. PD64-12 GENETIC RISK SCORE PREDICTS EARLY AGE-OF-ONSET OF PROSTATE CANCER Journal of Urology. 201. DOI: 10.1097/01.Ju.0000557451.76634.B7  0.489
2019 Pavlovich* C, Eskra J, Rabizadeh D, Zhang J, Isaacs W, Luo J. PD64-07 A NOVEL URINE TEST HIGHLY SPECIFIC FOR PROSTATE CANCER DETECTION Journal of Urology. 201. DOI: 10.1097/01.Ju.0000557446.23269.1B  0.614
2019 Faisal* F, Alshalalfa M, Davicioni E, Karnes RJ, Isaacs W, Lotan T, Schaeffer E. MP68-10 HOXB13 EXPRESSION AND ITS ROLE IN PROSTATE CANCER PROGRESSION AND NEUROENDOCRINE DIFFERENTIATION Journal of Urology. 201. DOI: 10.1097/01.Ju.0000557025.09954.39  0.623
2019 Black MH, Li S, LaDuca H, Gutierrez S, Lu H, Helfand* BT, Isaacs WB, Xu J. PD30-02 GERMLINE GENETIC ASSOCIATIONS WITH HIGH-RISK PROSTATE CANCER AND AGE AT DIAGNOSIS Journal of Urology. 201. DOI: 10.1097/01.Ju.0000556134.36362.7E  0.592
2018 Johng D, Torga G, Ewing CM, Jin K, Norris JD, McDonnell DP, Isaacs WB. HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancer. The Prostate. PMID 30560549 DOI: 10.1002/Pros.23747  0.598
2018 Carter HB, Helfand B, Mamawala M, Wu Y, Landis P, Yu H, Wiley K, Na R, Shi Z, Petkewicz J, Shah S, Fantus RJ, Novakovic K, Brendler CB, Zheng SL, ... Isaacs WB, et al. Germline Mutations in ATM and BRCA1/2 Are Associated with Grade Reclassification in Men on Active Surveillance for Prostate Cancer. European Urology. PMID 30309687 DOI: 10.1016/J.Eururo.2018.09.021  0.6
2018 Mottahedeh J, Haffner MC, Grogan TR, Hashimoto T, Crowell PD, Beltran H, Sboner A, Bareja R, Esopi D, Isaacs WB, Yegnasubramanian S, Rettig MB, Elashoff DA, Platz EA, De Marzo AM, et al. CD38 is methylated in prostate cancer and regulates extracellular NAD. Cancer & Metabolism. 6: 13. PMID 30258629 DOI: 10.1186/S40170-018-0186-3  0.569
2018 Langston ME, Pakpahan R, Nevin RL, De Marzo AM, Elliott DJ, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Platz EA, Sutcliffe S. Sustained influence of infections on prostate-specific antigen concentration: An analysis of changes over 10 years of follow-up. The Prostate. 78: 1024-1034. PMID 30133756 DOI: 10.1002/Pros.23660  0.512
2018 Wu Y, Yu H, Zheng SL, Feng B, Kapron AL, Na R, Boyle JL, Shah S, Shi Z, Ewing CM, Wiley KE, Luo J, Walsh PC, Carter HB, Helfand BT, ... ... Isaacs WB, et al. Germline mutations in PPFIBP2 are associated with lethal prostate cancer. The Prostate. PMID 30043417 DOI: 10.1002/Pros.23697  0.613
2018 Kallio HML, Hieta R, Latonen L, Brofeldt A, Annala M, Kivinummi K, Tammela TL, Nykter M, Isaacs WB, Lilja HG, Bova GS, Visakorpi T. Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases. British Journal of Cancer. PMID 29988112 DOI: 10.1038/S41416-018-0172-0  0.529
2018 Helfand BT, Chen H, Fantus RJ, Conran CA, Brendler CB, Zheng SL, Walsh PC, Isaacs WB, Xu J. Differences in inherited risk among relatives of hereditary prostate cancer patients using genetic risk score. The Prostate. PMID 29923209 DOI: 10.1002/Pros.23664  0.465
2018 Na R, Wu Y, Jiang G, Yu H, Lin X, Wang M, Conran CA, Fantus RJ, Zhang N, Liu S, Helfand BT, Zheng SL, Isaacs WB, Ding Q, Shen Z, et al. Germline Mutations in DNA Repair Genes are Associated with Bladder Cancer Risk and Unfavorable Prognosis. Bju International. PMID 29727914 DOI: 10.1111/Bju.14370  0.344
2018 Wedge DC, Gundem G, Mitchell T, Woodcock DJ, Martincorena I, Ghori M, Zamora J, Butler A, Whitaker H, Kote-Jarai Z, Alexandrov LB, Van Loo P, Massie CE, Dentro S, Warren AY, ... ... Isaacs W, et al. Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. Nature Genetics. PMID 29662167 DOI: 10.1038/S41588-018-0086-Z  0.595
2018 Wu Y, Yu H, Zheng SL, Na R, Mamawala M, Landis T, Wiley K, Petkewicz J, Shah S, Shi Z, Novakovic K, McGuire M, Brendler CB, Ding Q, Helfand BT, ... ... Isaacs WB, et al. A comprehensive evaluation of CHEK2 germline mutations in men with prostate cancer. The Prostate. PMID 29520813 DOI: 10.1002/Pros.23505  0.558
2018 Antonarakis ES, Lu C, Luber B, Liang C, Wang H, Chen Y, Silberstein JL, Piana D, Lai Z, Chen Y, Isaacs WB, Luo J. Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide. European Urology. PMID 29439820 DOI: 10.1016/J.Eururo.2018.01.035  0.546
2018 Isaacsson Velho P, Silberstein JL, Markowski MC, Luo J, Lotan TL, Isaacs WB, Antonarakis ES. Intraductal/ductal histology and lymphovascular invasion are associated with germline DNA-repair gene mutations in prostate cancer. The Prostate. PMID 29368341 DOI: 10.1002/Pros.23484  0.488
2018 Antonarakis ES, Lu C, Luber B, Wang H, Chen Y, Silberstein J, Piana D, Lai Z, Chen Y, Isaacs WB, Luo J. Effect of germline DNA repair gene mutations on outcomes in men with metastatic castration-resistant prostate cancer receiving first-line abiraterone and enzalutamide. Journal of Clinical Oncology. 36: 221-221. DOI: 10.1200/Jco.2018.36.6_Suppl.221  0.405
2018 Wang L, Xu M, Li Z, Shi M, Zhou X, Jiang X, Bryant J, Balk S, Ma J, Isaacs W, Xu X. Calcium and CaSR/IP3R in prostate cancer development Cell & Bioscience. 8. DOI: 10.1186/S13578-018-0217-3  0.34
2018 Isaacs W. Abstract IA02: Prostate cancer: DNA-based risk assessment Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-Ia02  0.626
2018 Eskra JN, Rabizadeh D, Pavlovich CP, Mangold L, Fabian E, Isaacs WB, Luo J. Abstract 651: Development of an RNA in situ hybridization assay for the detection of prostate cancer cells in urine Cancer Research. 78: 651-651. DOI: 10.1158/1538-7445.Am2018-651  0.621
2018 Kallio HM, Hieta R, Brofeldt A, Annala M, Kivinummi K, Tammela TL, Nykter M, Isaacs WB, Lilja HG, Bova GS, Visakorpi T. Abstract 1802: Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases Cancer Research. 78: 1802-1802. DOI: 10.1158/1538-7445.Am2018-1802  0.496
2018 Lam H, Zhu W, Wang H, Luo J, Zheng Q, Valkenburg K, Hurley P, Pluznick JL, Tran PT, Marzo AMD, Isaacs WB, Pienta KJ, An SS. Abstract 1094: A role for olfactory-like chemosensory signaling in prostate cancer metastasis Tumor Biology. DOI: 10.1158/1538-7445.Am2018-1094  0.573
2017 Kivinummi K, Urbanucci A, Leinonen K, Tammela TLJ, Annala M, Isaacs WB, Bova GS, Nykter M, Visakorpi T. The expression of AURKA is androgen regulated in castration-resistant prostate cancer. Scientific Reports. 7: 17978. PMID 29269934 DOI: 10.1038/S41598-017-18210-3  0.592
2017 Giri VN, Knudsen KE, Kelly WK, Abida W, Andriole GL, Bangma CH, Bekelman JE, Benson MC, Blanco A, Burnett A, Catalona WJ, Cooney KA, Cooperberg M, Crawford DE, Den RB, ... ... Isaacs WB, et al. Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017741173. PMID 29236593 DOI: 10.1200/Jco.2017.74.1173  0.436
2017 Chen H, Ewing CM, Zheng S, Grindedaal EM, Cooney KA, Wiley K, Djurovic S, Andreassen OA, Axcrona K, Mills IG, Xu J, Maehle L, Fosså SD, Isaacs WB. Genetic factors influencing prostate cancer risk in Norwegian men. The Prostate. PMID 29181843 DOI: 10.1002/Pros.23453  0.55
2017 Conti DV, Wang K, Sheng X, Bensen JT, Hazelett DJ, Cook MB, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Sanderson M, et al. Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry. Journal of the National Cancer Institute. 109. PMID 29117387 DOI: 10.1093/Jnci/Djx084  0.541
2017 Camacho N, Van Loo P, Edwards S, Kay JD, Matthews L, Haase K, Clark J, Dennis N, Thomas S, Kremeyer B, Zamora J, Butler AP, Gundem G, Merson S, Luxton H, ... ... Isaacs W, et al. Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data. Plos Genetics. 13: e1007001. PMID 28945760 DOI: 10.1371/Journal.Pgen.1007001  0.452
2017 Guedes L, Antonarakis ES, Schweizer MT, Mirkheshti N, Almutairi F, Park JC, Glavaris SA, Hicks JL, Eisenberger MA, De Marzo AM, Epstein JI, Isaacs WB, Eshleman JR, Pritchard CC, Lotan TL. MSH2 Loss in Primary Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28790115 DOI: 10.1158/1078-0432.Ccr-17-0955  0.638
2017 Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, ... ... Isaacs WB, et al. AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination. Nature Communications. 8: 142. PMID 28747635 DOI: 10.1038/S41467-017-00084-8  0.578
2017 Milbrandt M, Winter AC, Nevin RL, Pakpahan R, Bradwin G, De Marzo AM, Elliott DJ, Gaydos CA, Isaacs WB, Nelson WG, Rifai N, Sokoll LJ, Zenilman JM, Platz EA, Sutcliffe S. Insight into infection-mediated prostate damage: Contrasting patterns of C-reactive protein and prostate-specific antigen levels during infection. The Prostate. PMID 28703328 DOI: 10.1002/Pros.23392  0.531
2017 Na R, Helfand BT, Chen H, Conran CA, Crawford SE, Hayward SW, Tammela TLJ, Hoffman-Bolton J, Zheng SL, Walsh PC, Schleutker J, Platz EA, Isaacs WB, Xu J. A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). The Prostate. PMID 28656603 DOI: 10.1002/Pros.23380  0.525
2017 Guedes L, Almutairi F, Haffner MC, Rajoria G, Liu Z, Klimek S, Zoino R, Yousefi K, Sharma R, De Marzo AM, Netto G, Isaacs WB, Ross AE, Schaeffer EM, Lotan TL. Analytic, Pre-analytic and Clinical Validation of p53 Immunohistochemistry for Detection of TP53 Missense Mutation in Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28446506 DOI: 10.1158/1078-0432.Ccr-17-0257  0.434
2017 Winchester DA, Till C, Goodman PJ, Tangen CM, Santella RM, Johnson-Pais TL, Leach RJ, Xu J, Zheng SL, Thompson IM, Lucia MS, Lippman SM, Parnes HL, Isaacs WB, De Marzo AM, et al. Association between variants in genes involved in the immune response and prostate cancer risk in men randomized to the finasteride arm in the Prostate Cancer Prevention Trial. The Prostate. PMID 28317149 DOI: 10.1002/Pros.23346  0.552
2017 Larson NB, McDonnell S, Cannon Albright L, Teerlink C, Stanford J, Ostrander EA, Isaacs WB, Xu J, Cooney KA, Lange E, Schleutker J, Carpten JD, Powell I, Bailey-Wilson JE, Cussenot O, et al. gsSKAT: Rapid gene set analysis and multiple testing correction for rare-variant association studies using weighted linear kernels. Genetic Epidemiology. PMID 28211093 DOI: 10.1002/Gepi.22036  0.327
2017 Lotan TL, Torres A, Zhang M, Tosoian JJ, Guedes LB, Fedor H, Hicks J, Ewing CM, Isaacs SD, Johng D, De Marzo AM, Isaacs WB. Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers. Oncotarget. PMID 28186998 DOI: 10.18632/Oncotarget.15196  0.558
2017 Johng D, Ewing CM, Isaacs WB. Abstract 3524: HOXB13 collaborates with AR to alter the cellular phenotype of prostate epithelial cells through cytokeratin 14 upregulation Cancer Research. 77: 3524-3524. DOI: 10.1158/1538-7445.Am2017-3524  0.585
2017 Na R, Zheng S, Han M, Yu H, Jiang D, Shah S, Ewing C, Zhang L, Novakovic K, Petkewicz J, Gulukota K, Helseth D, Quinn M, Humphries E, Wiley K, ... ... Isaacs W, et al. Germline mutations in ATM and BRCA1/2 distinguish risk for lethal and indolent prostate cancer and are associated with early age at death European Urology Supplements. 16: e832-e833. DOI: 10.1016/S1569-9056(17)30541-9  0.445
2017 Na R, S. Lilly SL, Han M, Yu H, Jiang D, Shah S, Ewing C, Zhang L, Novakovic K, Petkewicz J, Gulukota K, Helseth Jr D, Quinn M, Humphries E, Wiley K, ... ... Isaacs W, et al. MP57-01 GERMLINE MUTATIONS IN DNA REPAIR GENES ARE SIGNIFICANTLY ENRICHED IN LETHAL PROSTATE CANCER AND ARE ASSOCIATED WITH DISEASE SURVIVAL Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1775  0.53
2017 Zheng SL, Na R, Han M, Novakovic K, Wiley K, Isaacs S, Partin A, McGuire M, Walsh P, Brendler C, Helfand B, Isaacs W, Xu J. CHEK2 MUTATIONS INCREASE RISK FOR PROSTATE CANCER BUT DO NOT DIFFERENTIATE RISK OF LETHAL FROM INDOLENT DISEASE Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1573  0.519
2016 Puhr M, De Marzo A, Isaacs W, Lucia MS, Sfanos K, Yegnasubramanian S, Culig Z. Inflammation, Microbiota, and Prostate Cancer. European Urology Focus. 2: 374-382. PMID 28723469 DOI: 10.1016/J.Euf.2016.08.010  0.781
2016 Na R, Zheng SL, Han M, Yu H, Jiang D, Shah S, Ewing CM, Zhang L, Novakovic K, Petkewicz J, Gulukota K, Helseth DL, Quinn M, Humphries E, Wiley KE, ... ... Isaacs WB, et al. Germline Mutations in ATM and BRCA1/2 Distinguish Risk for Lethal and Indolent Prostate Cancer and are Associated with Early Age at Death. European Urology. PMID 27989354 DOI: 10.1016/S1569-9056(17)30541-9  0.572
2016 Nickerson ML, Das S, Im KM, Turan S, Berndt SI, Li H, Lou H, Brodie SA, Billaud JN, Zhang T, Bouk AJ, Butcher D, Wang Z, Sun L, Misner K, ... ... Isaacs WB, et al. TET2 binds the androgen receptor and loss is associated with prostate cancer. Oncogene. PMID 27819678 DOI: 10.1038/Onc.2016.376  0.62
2016 Na R, Xu J, Isaacs WB. DNA-Repair Gene Mutations in Metastatic Prostate Cancer. The New England Journal of Medicine. 375: 1802-1803. PMID 27806230 DOI: 10.1056/Nejmc1611137  0.551
2016 Kumar B, Khaleghzadegan S, Mears B, Hatano K, Kudrolli TA, Chowdhury WH, Yeater DB, Ewing CM, Luo J, Isaacs WB, Marchionni L, Lupold SE. Identification of miR-30b-3p and miR-30d-5p as direct regulators of Androgen Receptor Signaling in Prostate Cancer by complementary functional microRNA library screening. Oncotarget. PMID 27683042 DOI: 10.18632/Oncotarget.12241  0.682
2016 Isaacs WB. What Do Myeloma, Breast Cancer, and Prostate Cancer Have in Common? European Urology. PMID 27600588 DOI: 10.1016/J.Eururo.2016.08.058  0.55
2016 Koboldt DC, Kanchi KL, Gui B, Larson DE, Fulton R, Isaacs WB, Kraja A, Borecki IB, Jia L, Wilson RK, Mardis ER, Kibel AS. Rare Variation in TET2 Is Associated with Clinically Relevant Prostate Carcinoma in African-Americans. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 27486019 DOI: 10.1158/1055-9965.Epi-16-0373  0.541
2016 Kulac I, Gumuskaya B, Drake CG, Gonzalez B, Arnold KB, Goodman PJ, Kristal AR, Lucia MS, Thompson IM, Isaacs WB, De Marzo AM, Platz EA. Peripheral zone inflammation is not strongly associated with lower urinary tract symptom incidence and progression in the placebo arm of the prostate cancer prevention trial . The Prostate. PMID 27325488 DOI: 10.1002/Pros.23224  0.526
2016 Larson NB, McDonnell S, Albright LC, Teerlink C, Stanford J, Ostrander EA, Isaacs WB, Xu J, Cooney KA, Lange E, Schleutker J, Carpten JD, Powell I, Bailey-Wilson J, Cussenot O, et al. Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies. Genetic Epidemiology. PMID 27312771 DOI: 10.1002/Gepi.21983  0.362
2016 Teerlink CC, Leongamornlert D, Dadaev T, Thomas A, Farnham J, Stephenson RA, Riska S, McDonnell SK, Schaid DJ, Catalona WJ, Zheng SL, Cooney KA, Ray AM, Zuhlke KA, Lange EM, ... ... Isaacs WB, et al. Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21. Human Genetics. PMID 27262462 DOI: 10.1007/S00439-016-1690-6  0.491
2016 Chen H, Liu X, Brendler CB, Ankerst DP, Leach RJ, Goodman PJ, Lucia MS, Tangen CM, Wang L, Hsu FC, Sun J, Kader AK, Isaacs WB, Helfand BT, Zheng SL, et al. Adding genetic risk score to family history identifies twice as many high-risk men for prostate cancer: Results from the prostate cancer prevention trial. The Prostate. PMID 27197965 DOI: 10.1002/Pros.23200  0.54
2016 Bova GS, Kallio HM, Annala M, Kivinummi K, Högnäs G, Häyrynen S, Rantapero T, Kivinen V, Isaacs WB, Tolonen T, Nykter M, Visakorpi T. Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer. Cold Spring Harbor Molecular Case Studies. 2: a000752. PMID 27148588 DOI: 10.1101/mcs.a000752  0.43
2016 Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, et al. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nature Communications. 7: 10979. PMID 27052111 DOI: 10.1038/Ncomms10979  0.564
2016 Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, et al. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. Journal of the National Cancer Institute. 108. PMID 26823525 DOI: 10.1093/Jnci/Djv431  0.563
2016 Winchester DA, Gurel B, Till C, Goodman PJ, Tangen CM, Santella RM, Johnson-Pais TL, Leach RJ, Thompson IM, Xu J, Zheng SL, Lucia MS, Lippman SM, Parnes HL, Isaacs WB, et al. Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial. The Prostate. PMID 26771888 DOI: 10.1002/Pros.23147  0.633
2016 Cropp CD, McDonnell SK, Middha S, DeRycke M, Karyadi DM, Schaid D, Thibodeau SN, Isaacs WB, Ostrander EA, Stanford J, Cooney KA, Bailey-Wilson JE, Carpten JD. Abstract B40: Rare variant discovery in known cancer genes from whole-exome sequencingof African American hereditary prostate cancer families Cancer Epidemiology, Biomarkers & Prevention. 25. DOI: 10.1158/1538-7755.Disp15-B40  0.523
2016 Johng D, Haffner MC, Mooney SM, Esopi DM, Ewing CM, Chen S, Isaacs WB. Abstract 2027: Global analyses of HOXB13-regulated transcription reveal a potential link between HOXB13 G84E and prostate cancer risk Cancer Research. 76: 2027-2027. DOI: 10.1158/1538-7445.Am2016-2027  0.628
2016 Chen H, Packiam VT, Helfand BT, Conran CA, Zheng SL, Isaacs WB, Brendler CB, Xu J. MP07-08 THE PLATEAU EFFECT OF NUMBER OF PROSTATE CANCER RISK-ASSOCIATED SINGLE NUCLEOTIDE POLYMORPHISMS USED TO ASSESS GENETIC RISK Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.2211  0.523
2016 Helfand BT, Packiam VT, Chen H, Zheng SL, Conran CA, Brendler CB, Isaacs WB, Xu J. PD15-06 GENETIC RISK SCORE DIFFERENTIATES INHERITED RISK AMONG RELATIVES OF PATIENTS WITH HEREDITARY PROSTATE CANCER Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.1132  0.405
2015 Kibel AS, Ahn J, Isikbay M, Klim A, Wu WS, Hayes RB, Isaacs WB, Daw EW. Genetic variants in cell cycle control pathway confer susceptibility to aggressive prostate carcinoma. The Prostate. PMID 26708993 DOI: 10.1002/Pros.23139  0.576
2015 Sutcliffe S, Nevin RL, Pakpahan R, Elliott DJ, Langston ME, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Walsh PC, Zenilman JM, Cersovsky SB, Platz EA. Infectious Mononucleosis, Other Infections, and Prostate-Specific Antigen Concentration as a Marker of Prostate Involvement During Infection. International Journal of Cancer. Journal International Du Cancer. PMID 26678984 DOI: 10.1002/Ijc.29966  0.576
2015 Lynch HT, Kosoko-Lasaki O, Leslie SW, Rendell M, Shaw T, Snyder C, D'Amico AV, Buxbaum S, Isaacs WB, Loeb S, Moul JW, Powell I. Screening for Familial and Hereditary Prostate Cancer. International Journal of Cancer. Journal International Du Cancer. PMID 26638190 DOI: 10.1002/Ijc.29949  0.493
2015 Hurley PJ, Sundi D, Shinder B, Simons B, Hughes RM, Miller RM, Benzon B, Faraj SF, Netto GJ, Vergara IA, Erho N, Davicioni E, Karnes RJ, Yan G, Ewing CM, ... ... Isaacs WB, et al. Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment and are Differentially Associated with Metastatic Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26446945 DOI: 10.1158/1078-0432.Ccr-15-0256  0.588
2015 Wang M, Takahashi A, Liu F, Ye D, Ding Q, Qin C, Yin C, Zhang Z, Matsuda K, Kubo M, Na R, Lin X, Jiang H, Ren S, Sun J, ... ... Isaacs WB, et al. Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer. Nature Communications. 6: 8469. PMID 26443449 DOI: 10.1038/Ncomms9469  0.618
2015 Haffner MC, Weier C, Xu M, Vaghasia A, Gürel B, Gümüşkaya B, Esopi DM, Fedor H, Tan HL, Kulac I, Hicks J, Isaacs WB, Lotan TL, Nelson WG, Yegnasubramanian S, et al. Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization. The Journal of Pathology. PMID 26331372 DOI: 10.1002/Path.4628  0.518
2015 Tsai H, Morais CL, Alshalalfa M, Tan HL, Haddad Z, Hicks JL, Gupta N, Epstein JI, Netto GJ, Isaacs WB, Luo J, Mehra R, Vessella RL, Karnes RJ, Schaeffer E, et al. Cyclin D1 Loss Distinguishes Prostatic Small Cell Carcinoma from Most Prostatic Adenocarcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26246306 DOI: 10.1158/1078-0432.Ccr-15-0744  0.536
2015 Han Y, Hazelett DJ, Wiklund F, Schumacher FR, Stram DO, Berndt SI, Wang Z, Rand KA, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, ... ... Isaacs WB, et al. Integration of Multiethnic Fine-mapping and Genomic Annotation to Prioritize Candidate Functional SNPs at Prostate Cancer Susceptibility Regions. Human Molecular Genetics. PMID 26162851 DOI: 10.1093/Hmg/Ddv269  0.445
2015 Beebe-Dimmer JL, Hathcock M, Yee C, Okoth LA, Ewing CM, Isaacs WB, Cooney KA, Thibodeau SN. The HOXB13 G84E Mutation Is Associated with an Increased Risk for Prostate Cancer and Other Malignancies. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 1366-72. PMID 26108461 DOI: 10.1158/1055-9965.Epi-15-0247  0.576
2015 Winchester DA, Till C, Goodman PJ, Tangen CM, Santella RM, Johnson-Pais TL, Leach RJ, Xu J, Zheng SL, Thompson IM, Lucia MS, Lippmann SM, Parnes HL, Dluzniewski PJ, Isaacs WB, et al. Variation in genes involved in the immune response and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial. The Prostate. PMID 26047319 DOI: 10.1002/Pros.23021  0.648
2015 Gundem G, Van Loo P, Kremeyer B, Alexandrov LB, Tubio JM, Papaemmanuil E, Brewer DS, Kallio HM, Högnäs G, Annala M, Kivinummi K, Goody V, Latimer C, O'Meara S, Dawson KJ, ... Isaacs W, et al. The evolutionary history of lethal metastatic prostate cancer. Nature. 520: 353-7. PMID 25830880 DOI: 10.1038/Nature14347  0.587
2015 Helfand BT, Roehl KA, Cooper PR, McGuire BB, Fitzgerald LM, Cancel-Tassin G, Cornu JN, Bauer S, Van Blarigan EL, Chen X, Duggan D, Ostrander EA, Gwo-Shu M, Zhang ZF, Chang SC, ... ... Isaacs WB, et al. Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. Human Genetics. 134: 439-50. PMID 25715684 DOI: 10.1007/S00439-015-1534-9  0.423
2015 Dluzniewski PJ, Xu J, Ruczinski I, Isaacs WB, Platz EA. Polymorphisms influencing prostate-specific antigen concentration may bias genome-wide association studies on prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 88-93. PMID 25352524 DOI: 10.1158/1055-9965.Epi-14-0863  0.565
2015 Loeb S, Peskoe SB, Joshu CE, Huang WY, Hayes RB, Carter HB, Isaacs WB, Platz EA. Do environmental factors modify the genetic risk of prostate cancer? Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 213-20. PMID 25342390 DOI: 10.1158/1055-9965.Epi-14-0786-T  0.541
2015 Karantanos T, Evans CP, Tombal B, Thompson TC, Montironi R, Isaacs WB. Understanding the mechanisms of androgen deprivation resistance in prostate cancer at the molecular level. European Urology. 67: 470-9. PMID 25306226 DOI: 10.1016/J.Eururo.2014.09.049  0.555
2015 Han Y, Signorello LB, Strom SS, Kittles RA, Rybicki BA, Stanford JL, Goodman PJ, Berndt SI, Carpten J, Casey G, Chu L, Conti DV, Rand KA, Diver WR, Hennis AJ, ... ... Isaacs W, et al. Generalizability of established prostate cancer risk variants in men of African ancestry. International Journal of Cancer. Journal International Du Cancer. 136: 1210-7. PMID 25044450 DOI: 10.1002/Ijc.29066  0.556
2015 Antonarakis ES, Lu C, Chen Y, Luber B, Wang H, Nakazawa M, De Marzo AM, Isaacs WB, Nadal R, Paller CJ, Denmeade SR, Carducci MA, Eisenberger MA, Luo J. AR splice variant 7 (AR-V7) and response to taxanes in men with metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 33: 138-138. DOI: 10.1200/Jco.2015.33.7_Suppl.138  0.408
2015 Liu W, Rodrigues LU, Li T, Zhang Z, Rider L, Romero L, Zheng LS, Isaacs WB, Cramer S, Xu J. Abstract A1-04: The role of chromatin remodeler CHD1 in genomic alterations and prostate cancer progression Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-04  0.548
2015 Johng D, Haffner MC, Esopi DM, Isaacs WB. Abstract 961: Genome– and proteome–wide analyses of HOXB13 and the G84E variant associated with prostate cancer Cancer Research. 75: 961-961. DOI: 10.1158/1538-7445.Am2015-961  0.636
2015 Gundem G, Loo PV, Kremeyer B, Alexandrov LB, Tubio JMC, Papaemmanuil E, Brewer DS, Kallio H, Högnäs G, Annala M, Kivinummi K, Goody V, Latimer C, O'Meara S, Dawson KJ, ... Isaacs W, et al. Abstract 956: The evolutionary history of lethal metastatic prostate cancer Cancer Research. 75: 956-956. DOI: 10.1158/1538-7445.Am2015-956  0.593
2015 Winchester DA, Till C, Goodman PJ, Tangen CM, Santella RM, Johnson-Pais TL, Leach RJ, Xu J, Zheng SL, Thompson IM, Lucia MS, Lippmann SM, Parnes HL, Dluzniewski PJ, Isaacs WB, et al. Abstract 4605: Variation in genes involved in the immune response and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial Cancer Research. 75: 4605-4605. DOI: 10.1158/1538-7445.Am2015-4605  0.595
2015 Kallio HML, Annala M, Kivinummi K, Högnäs G, Gundem G, Wedge DC, Loo PV, Heyn H, Emmert-Buck MR, Isaacs WB, Esteller M, McDermott U, Nykter M, Visakorpi T, Bova GS. Abstract 3883: Clonal evolution of a lethal prostate cancer: Integrated whole genome analysis case study Cancer Research. 75: 3883-3883. DOI: 10.1158/1538-7445.Am2015-3883  0.531
2014 Ju YS, Alexandrov LB, Gerstung M, Martincorena I, Nik-Zainal S, Ramakrishna M, Davies HR, Papaemmanuil E, Gundem G, Shlien A, Bolli N, Behjati S, Tarpey PS, Nangalia J, Massie CE, ... ... Isaacs WB, et al. Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer. Elife. 3. PMID 25271376 DOI: 10.7554/Elife.02935  0.324
2014 Lopez DS, Peskoe SB, Tsilidis KK, Hoffman-Bolton J, Helzlsouer KJ, Isaacs WB, Smith MW, Platz EA. Association of variants in genes related to the immune response and obesity with BPH in CLUE II. Prostate Cancer and Prostatic Diseases. 17: 353-8. PMID 25224558 DOI: 10.1038/Pcan.2014.36  0.364
2014 Al Olama AA, Kote-Jarai Z, Berndt SI, Conti DV, Schumacher F, Han Y, Benlloch S, Hazelett DJ, Wang Z, Saunders E, Leongamornlert D, Lindstrom S, Jugurnauth-Little S, Dadaev T, Tymrakiewicz M, ... ... Isaacs WB, et al. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nature Genetics. 46: 1103-9. PMID 25217961 DOI: 10.1038/Ng.3094  0.627
2014 Antonarakis ES, Lu C, Wang H, Luber B, Nakazawa M, Roeser JC, Chen Y, Mohammad TA, Chen Y, Fedor HL, Lotan TL, Zheng Q, De Marzo AM, Isaacs JT, Isaacs WB, et al. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. The New England Journal of Medicine. 371: 1028-38. PMID 25184630 DOI: 10.1056/Nejmoa1315815  0.525
2014 Bhavsar NA, Bream JH, Meeker AK, Drake CG, Peskoe SB, Dabitao D, De Marzo AM, Isaacs WB, Platz EA. A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 2561-7. PMID 25150281 DOI: 10.1158/1055-9965.Epi-14-0010  0.62
2014 Zuhlke KA, Johnson AM, Tomlins SA, Palanisamy N, Carpten JD, Lange EM, Isaacs WB, Cooney KA. Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer. The Prostate. 74: 983-90. PMID 24796539 DOI: 10.1002/Pros.22818  0.62
2014 Lange EM, Johnson AM, Wang Y, Zuhlke KA, Lu Y, Ribado JV, Keele GR, Li J, Duan Q, Li G, Gao Z, Li Y, Xu J, Isaacs WB, Zheng S, et al. Genome-wide association scan for variants associated with early-onset prostate cancer. Plos One. 9: e93436. PMID 24740154 DOI: 10.1371/Journal.Pone.0093436  0.613
2014 Tan HL, Sood A, Rahimi HA, Wang W, Gupta N, Hicks J, Mosier S, Gocke CD, Epstein JI, Netto GJ, Liu W, Isaacs WB, De Marzo AM, Lotan TL. Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 890-903. PMID 24323898 DOI: 10.1158/1078-0432.Ccr-13-1982  0.6
2014 Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK. Telomere length as a risk factor for hereditary prostate cancer. The Prostate. 74: 359-64. PMID 24285042 DOI: 10.1002/Pros.22755  0.753
2014 Teerlink CC, Thibodeau SN, McDonnell SK, Schaid DJ, Rinckleb A, Maier C, Vogel W, Cancel-Tassin G, Egrot C, Cussenot O, Foulkes WD, Giles GG, Hopper JL, Severi G, Eeles R, ... ... Isaacs WB, et al. Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease. Human Genetics. 133: 347-56. PMID 24162621 DOI: 10.1007/S00439-013-1384-2  0.638
2014 Beebe-Dimmer JL, Isaacs WB, Zuhlke KA, Yee C, Walsh PC, Isaacs SD, Johnson AM, Ewing CE, Humphreys EB, Chowdhury WH, Montie JE, Cooney KA. Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy. Bju International. 113: 830-5. PMID 24148311 DOI: 10.1111/Bju.12522  0.595
2014 Ju YS, Alexandrov LB, Gerstung M, Martincorena I, Nik-Zainal S, Ramakrishna M, Davies HR, Papaemmanuil E, Gundem G, Shlien A, Bolli N, Behjati S, Tarpey PS, Nangalia J, Massie CE, ... ... Isaacs WB, et al. Author response: Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer Elife. DOI: 10.7554/Elife.02935.028  0.303
2014 Antonarakis ES, Lu C, Wang H, Luber B, Nakazawa M, Chen Y, Roeser JC, Fedor HL, Lotan TL, Zheng Q, De Marzo AM, Isaacs JT, Isaacs WB, Nadal R, Paller CJ, et al. Androgen receptor splice variant, AR-V7, and resistance to enzalutamide and abiraterone in men with metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 32: 5001-5001. DOI: 10.1200/Jco.2014.32.15_Suppl.5001  0.481
2014 Beebe-Dimmer J, Isaacs WB, Thibodeau SN, Yee C, Ewing C, Okoth L, Cooney KA. Association of the HOXB13 G84E mutation with increased risk for prostate cancer and other malignancies. Journal of Clinical Oncology. 32: 1558-1558. DOI: 10.1200/Jco.2014.32.15_Suppl.1558  0.575
2014 Han Y, Signorello LB, Strom SS, Kittles RA, Rybicki BA, Stanford JL, Goodman PJ, Berndt SI, Carpten J, Casey G, Chu L, Conti DV, Rand KA, Diver R, Hennis AJ, ... ... Isaacs WB, et al. Abstract 5066: Generalizability of established prostate cancer risk variants in men of African ancestry Cancer Research. 74: 5066-5066. DOI: 10.1158/1538-7445.Am2014-5066  0.578
2014 Johng D, Ewing CM, Mooney SM, Chen S, Isaacs WB. Abstract 2948: HOXB13: Investigating mechanisms of G84E mutation associated with prostate carcinogenesis Cancer Research. 74: 2948-2948. DOI: 10.1158/1538-7445.Am2014-2948  0.585
2014 Antonarakis ES, Lu C, Wang H, Luber B, Nakazawa M, Roeser JC, Chen Y, Fedor HL, Lotan TL, Marzo AMD, Isaacs JT, Isaacs WB, Nadal R, Paller CJ, Denmeade SR, et al. Abstract 2910: Androgen receptor splice variant-7 predicts resistance to enzalutamide in patients with castration-resistant prostate cancer Cancer Research. 74: 2910-2910. DOI: 10.1158/1538-7445.Am2014-2910  0.526
2014 Antonarakis E, Lu C, Wang H, Luber B, Nakazawa M, Roeser J, Chen Y, Fedor H, Lotan T, Zheng Q, De Marzo A, Isaacs J, Isaacs W, Nadal R, Paller C, et al. Ar-V7 Splice Variant and Resistance to Enzalutamide and Abiraterone in Men with Metastatic Castration-Resistant Prostate Cancer (Mcrpc): Overall Survival Results Annals of Oncology. 25: v1. DOI: 10.1093/Annonc/Mdu438.23  0.536
2014 Chen S, Johng D, Ewing C, Isaacs W. MP31-03 ALTERED HOXB13 FUNCTION IN HUMAN PROSTATE CANCER Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.912  0.615
2014 Loeb S, Peskoe S, Joshu C, Huang W, Hayes R, Carter HB, Isaacs W, Platz E. PD31-04 DO ENVIRONMENTAL FACTORS MODIFY THE GENETIC RISK OF PROSTATE CANCER? Journal of Urology. 191. DOI: 10.1016/j.juro.2014.02.2263  0.404
2014 Chen H, Sun J, Ankerst D, Leach R, Goodman P, Lucia S, Tangen C, Isaacs W, Zheng SL, Thompson I, Platz E, Xu J. MP69-12 ADDED VALUE OF GENETIC RISK SCORE TO THE PROSTATE CANCER PREVENTION TRIAL (PCPT) RISK CALCULATOR: FINDINGS FROM THE PCPT STUDY Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.2231  0.536
2013 Sfanos KS, Isaacs WB, De Marzo AM. Infections and inflammation in prostate cancer. American Journal of Clinical and Experimental Urology. 1: 3-11. PMID 25110720  0.773
2013 Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, et al. Tracking the clonal origin of lethal prostate cancer. The Journal of Clinical Investigation. 123: 4918-22. PMID 24135135 DOI: 10.1172/Jci70354  0.745
2013 Leinonen KA, Saramäki OR, Furusato B, Kimura T, Takahashi H, Egawa S, Suzuki H, Keiger K, Ho Hahm S, Isaacs WB, Tolonen TT, Stenman UH, Tammela TL, Nykter M, Bova GS, et al. Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 22: 2333-44. PMID 24083995 DOI: 10.1158/1055-9965.Epi-13-0333-T  0.581
2013 Liu W, Xie CC, Thomas CY, Kim ST, Lindberg J, Egevad L, Wang Z, Zhang Z, Sun J, Sun J, Koty PP, Kader AK, Cramer SD, Bova GS, Zheng SL, ... ... Isaacs WB, et al. Genetic markers associated with early cancer-specific mortality following prostatectomy. Cancer. 119: 2405-12. PMID 23609948 DOI: 10.1002/Cncr.27954  0.541
2013 Chen Z, Sun J, Kim ST, Groskopf J, Feng J, Isaacs WB, Rittmaster RS, Condreay LD, Zheng SL, Xu J. Genome-wide association study identifies genetic determinants of urine PCA3 levels in men. Neoplasia (New York, N.Y.). 15: 448-53. PMID 23555189 DOI: 10.1593/Neo.122144  0.565
2013 Rebbeck TR, Devesa SS, Chang BL, Bunker CH, Cheng I, Cooney K, Eeles R, Fernandez P, Giri VN, Gueye SM, Haiman CA, Henderson BE, Heyns CF, Hu JJ, Ingles SA, ... Isaacs W, et al. Global patterns of prostate cancer incidence, aggressiveness, and mortality in men of african descent. Prostate Cancer. 2013: 560857. PMID 23476788 DOI: 10.1155/2013/560857  0.521
2013 Weier C, Haffner MC, Mosbruger T, Esopi DM, Hicks J, Zheng Q, Fedor H, Isaacs WB, De Marzo AM, Nelson WG, Yegnasubramanian S. Nucleotide resolution analysis of TMPRSS2 and ERG rearrangements in prostate cancer. The Journal of Pathology. 230: 174-83. PMID 23447416 DOI: 10.1002/Path.4186  0.558
2013 Chen Z, Greenwood C, Isaacs WB, Foulkes WD, Sun J, Zheng SL, Condreay LD, Xu J. The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial. Carcinogenesis. 34: 1260-4. PMID 23393222 DOI: 10.1093/Carcin/Bgt055  0.465
2013 Jin G, Zheng SL, Lilja H, Kim ST, Tao S, Gao Z, Young T, Wiklund F, Feng J, Isaacs WB, Rittmaster RS, Gronberg H, Condreay LD, Sun J, Xu J. Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA. Neoplasia (New York, N.Y.). 15: 95-101. PMID 23359319 DOI: 10.1593/Neo.121620  0.531
2013 Aryee MJ, Liu W, Engelmann JC, Nuhn P, Gurel M, Haffner MC, Esopi D, Irizarry RA, Getzenberg RH, Nelson WG, Luo J, Xu J, Isaacs WB, Bova GS, Yegnasubramanian S. DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases. Science Translational Medicine. 5: 169ra10. PMID 23345608 DOI: 10.1126/Scitranslmed.3005211  0.425
2013 Hong MG, Karlsson R, Magnusson PK, Lewis MR, Isaacs W, Zheng LS, Xu J, Grönberg H, Ingelsson E, Pawitan Y, Broeckling C, Prenni JE, Wiklund F, Prince JA. A genome-wide assessment of variability in human serum metabolism. Human Mutation. 34: 515-24. PMID 23281178 DOI: 10.1002/Humu.22267  0.39
2013 Amin Al Olama A, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Hunter DJ, Henderson BE, Thun MJ, Gaziano M, ... ... Isaacs W, et al. A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. Human Molecular Genetics. 22: 408-15. PMID 23065704 DOI: 10.1093/Hmg/Dds425  0.464
2013 Xu J, Lange EM, Lu L, Zheng SL, Wang Z, Thibodeau SN, Cannon-Albright LA, Teerlink CC, Camp NJ, Johnson AM, Zuhlke KA, Stanford JL, Ostrander EA, Wiley KE, Isaacs SD, ... ... Isaacs WB, et al. HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). Human Genetics. 132: 5-14. PMID 23064873 DOI: 10.1007/S00439-012-1229-4  0.629
2013 Chen S, Isaacs WB. Abstract A04: HOXB13 regulates androgen receptor expression in prostate cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A04  0.551
2013 Chen S, Johng D, Isaacs WB. Abstract 753: Reciprocal regulation of HOXB13 and androgen receptor in prostate cancer. Cancer Research. 73: 753-753. DOI: 10.1158/1538-7445.Am2013-753  0.622
2013 Bhavsar NA, Bream JJ, Meeker AK, Drake CG, Peskoe SB, Marzo AMD, Isaacs WB, Platz EA. Abstract 3618: Peripheral cytokine profiles and prostate cancer risk in CLUE II. Cancer Research. 73: 3618-3618. DOI: 10.1158/1538-7445.Am2013-3618  0.682
2013 Weier C, Haffner M, Mosbruger T, Esopi D, Hicks J, Zheng Q, Isaacs WB, Marzo AMD, Nelson WG, Yegnasubramanian S. Abstract 1773: Nucleotide-resolution genomic breakpoint analysis of TMPRSS2-ERG rearrangements in prostate cancer by target-capture next-generation sequencing. Cancer Research. 73: 1773-1773. DOI: 10.1158/1538-7445.Am2013-1773  0.554
2013 Beebe-Dimmer J, Isaacs W, Zuhlke K, Yee C, Walsh P, Isaacs S, Cooney K. 2137 THE PREVALENCE OF THE HOXB13 GLY84GLU PROSTATE CANCER RISK ALLELE IN MEN TREATED WITH RADICAL PROSTATECTOMY Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.2046  0.597
2012 Kim JW, Kim ST, Turner AR, Young T, Smith S, Liu W, Lindberg J, Egevad L, Gronberg H, Isaacs WB, Xu J. Identification of new differentially methylated genes that have potential functional consequences in prostate cancer. Plos One. 7: e48455. PMID 23119026 DOI: 10.1371/Journal.Pone.0048455  0.361
2012 Jin G, Sun J, Kim ST, Feng J, Wang Z, Tao S, Chen Z, Purcell L, Smith S, Isaacs WB, Rittmaster RS, Zheng SL, Condreay LD, Xu J. Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men. Human Molecular Genetics. 21: 5222-8. PMID 22936694 DOI: 10.1093/Hmg/Dds361  0.306
2012 Zuhlke KA, Johnson AM, Okoth LA, Stoffel EM, Robbins CM, Tembe WA, Salinas CA, Zheng SL, Xu J, Carpten JD, Lange EM, Isaacs WB, Cooney KA. Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer. Familial Cancer. 11: 595-600. PMID 22864661 DOI: 10.1007/S10689-012-9555-1  0.61
2012 Dluzniewski PJ, Wang MH, Zheng SL, De Marzo AM, Drake CG, Fedor HL, Partin AW, Han M, Fallin MD, Xu J, Isaacs WB, Platz EA. Variation in IL10 and other genes involved in the immune response and in oxidation and prostate cancer recurrence. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 1774-82. PMID 22859398 DOI: 10.1158/1055-9965.Epi-12-0458  0.394
2012 Bailey-Wilson JE, Childs EJ, Cropp CD, Schaid DJ, Xu J, Camp NJ, Cannon-Albright LA, Farnham JM, George A, Powell I, Carpten JD, Giles GG, Hopper JL, Severi G, English DR, ... ... Isaacs WB, et al. Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families. Bmc Medical Genetics. 13: 46. PMID 22712434 DOI: 10.1186/1471-2350-13-46  0.524
2012 Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, Edwards J, Isaacs WB, Nelson PS, Bluemn E, Plymate SR, Luo J. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Research. 72: 3457-62. PMID 22710436 DOI: 10.1158/0008-5472.Can-11-3892  0.486
2012 Choudhury AD, Eeles R, Freedland SJ, Isaacs WB, Pomerantz MM, Schalken JA, Tammela TL, Visakorpi T. The role of genetic markers in the management of prostate cancer. European Urology. 62: 577-87. PMID 22695242 DOI: 10.1016/J.Eururo.2012.05.054  0.609
2012 Kader AK, Sun J, Reck BH, Newcombe PJ, Kim ST, Hsu FC, D'Agostino RB, Tao S, Zhang Z, Turner AR, Platek GT, Spraggs CF, Whittaker JC, Lane BR, Isaacs WB, et al. Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial. European Urology. 62: 953-61. PMID 22652152 DOI: 10.1016/J.Eururo.2012.05.006  0.51
2012 Hager MH, Morley S, Bielenberg DR, Gao S, Morello M, Holcomb IN, Liu W, Mouneimne G, Demichelis F, Kim J, Solomon KR, Adam RM, Isaacs WB, Higgs HN, Vessella RL, et al. DIAPH3 governs the cellular transition to the amoeboid tumour phenotype. Embo Molecular Medicine. 4: 743-60. PMID 22593025 DOI: 10.1002/Emmm.201200242  0.374
2012 Isaacs WB. Inherited susceptibility for aggressive prostate cancer. Asian Journal of Andrology. 14: 415-8. PMID 22543676 DOI: 10.1038/Aja.2011.146  0.642
2012 Tao S, Feng J, Webster T, Jin G, Hsu FC, Chen SH, Kim ST, Wang Z, Zhang Z, Zheng SL, Isaacs WB, Xu J, Sun J. Genome-wide two-locus epistasis scans in prostate cancer using two European populations. Human Genetics. 131: 1225-34. PMID 22367438 DOI: 10.1007/S00439-012-1148-4  0.398
2012 Ewing CM, Ray AM, Lange EM, Zuhlke KA, Robbins CM, Tembe WD, Wiley KE, Isaacs SD, Johng D, Wang Y, Bizon C, Yan G, Gielzak M, Partin AW, Shanmugam V, ... ... Isaacs WB, et al. Germline mutations in HOXB13 and prostate-cancer risk. The New England Journal of Medicine. 366: 141-9. PMID 22236224 DOI: 10.1056/Nejmoa1110000  0.633
2012 Tao S, Wang Z, Feng J, Hsu FC, Jin G, Kim ST, Zhang Z, Gronberg H, Zheng LS, Isaacs WB, Xu J, Sun J. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. Carcinogenesis. 33: 598-603. PMID 22219177 DOI: 10.1093/Carcin/Bgr316  0.429
2012 Thomas JA, Gerber L, Moreira DM, Hamilton RJ, Bañez LL, Castro-Santamaria R, Andriole GL, Isaacs WB, Xu J, Freedland SJ. Prostate cancer risk in men with prostate and breast cancer family history: results from the REDUCE study (R1). Journal of Internal Medicine. 272: 85-92. PMID 22211699 DOI: 10.1111/J.1365-2796.2011.02504.X  0.615
2012 Jin G, Lu L, Cooney KA, Ray AM, Zuhlke KA, Lange EM, Cannon-Albright LA, Camp NJ, Teerlink CC, Fitzgerald LM, Stanford JL, Wiley KE, Isaacs SD, Walsh PC, Foulkes WD, ... ... Isaacs WB, et al. Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG). Human Genetics. 131: 1095-103. PMID 22198737 DOI: 10.1007/S00439-011-1136-0  0.51
2012 Liu W, Lindberg J, Sui G, Luo J, Egevad L, Li T, Xie C, Wan M, Kim ST, Wang Z, Turner AR, Zhang Z, Feng J, Yan Y, Sun J, ... ... Isaacs WB, et al. Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer. Oncogene. 31: 3939-48. PMID 22139082 DOI: 10.1038/Onc.2011.554  0.568
2012 Lu L, Cancel-Tassin G, Valeri A, Cussenot O, Lange EM, Cooney KA, Farnham JM, Camp NJ, Cannon-Albright LA, Tammela TL, Schleutker J, Hoegel J, Herkommer K, Maier C, Vogel W, ... ... Isaacs WB, et al. Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG. The Prostate. 72: 410-26. PMID 21748754 DOI: 10.1002/Pros.21443  0.444
2012 Lu Y, Sun J, Kader AK, Kim ST, Kim JW, Liu W, Sun J, Lu D, Feng J, Zhu Y, Jin T, Zhang Z, Dimitrov L, Lowey J, Campbell K, ... ... Isaacs WB, et al. Association of prostate cancer risk with SNPs in regions containing androgen receptor binding sites captured by ChIP-On-chip analyses. The Prostate. 72: 376-85. PMID 21671247 DOI: 10.1002/Pros.21439  0.475
2012 Morley S, Hager MH, Bielenberg DR, Gao SG, Morello M, Holcomb IN, Liu W, Mouneimne G, Demichelis F, Kim J, Solomon KR, Adam RM, Isaacs WB, Higgs HN, Vessella RL, et al. Abstract 486: The novel tumor suppressorDIAPH3governs transition to an amoeboid phenotype Cancer Research. 72: 486-486. DOI: 10.1158/1538-7445.Am2012-486  0.527
2012 Chung CC, Hsing AW, Yeager M, Yeboah E, Biritwum R, Tettey Y, Adjei A, Marzo AD, Netto GJ, Isaacs WB, Isaacs SD, Boland J, Chanock SJ. Abstract 3974: A comprehensive resequence-analysis of 250kb region of 8q24 in Africans Cancer Research. 72: 3974-3974. DOI: 10.1158/1538-7445.Am2012-3974  0.511
2012 Ishak MB, Ray AM, Robbins CM, Tembe WD, Carpten JD, Lange EM, Isaacs WB, Cooney KA. Abstract 1642: Rare missense variants inMAP3K14andARHGAP27in men with hereditary prostate cancer Cancer Research. 72: 1642-1642. DOI: 10.1158/1538-7445.Am2012-1642  0.577
2012 Thomas J, Gerber L, Moreira DM, Hamilton RJ, Bañez LL, Castro RS, Andriole GL, Isaacs WB, Xu J, Freedland SJ. 159 PROSTATE CANCER RISK IN MEN WITH PROSTATE AND BREAST CANCER FAMILY HISTORY: RESULTS FROM THE REDUCE STUDY Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.210  0.615
2011 Feng J, Sun J, Kim ST, Lu Y, Wang Z, Zhang Z, Gronberg H, Isaacs WB, Zheng SL, Xu J. A genome-wide survey over the ChIP-on-chip identified androgen receptor-binding genomic regions identifies a novel prostate cancer susceptibility locus at 12q13.13. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 2396-403. PMID 21960693 DOI: 10.1158/1055-9965.Epi-11-0523  0.518
2011 Lotan TL, Gurel B, Sutcliffe S, Esopi D, Liu W, Xu J, Hicks JL, Park BH, Humphreys E, Partin AW, Han M, Netto GJ, Isaacs WB, De Marzo AM. PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6563-73. PMID 21878536 DOI: 10.1158/1078-0432.Ccr-11-1244  0.552
2011 Cheng Y, Liu W, Kim ST, Sun J, Lu L, Sun J, Zheng SL, Isaacs WB, Xu J. Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study. Cancer Genetics. 204: 375-81. PMID 21872824 DOI: 10.1016/J.Cancergen.2011.05.002  0.583
2011 Jin G, Sun J, Isaacs SD, Wiley KE, Kim ST, Chu LW, Zhang Z, Zhao H, Zheng SL, Isaacs WB, Xu J. Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk. Carcinogenesis. 32: 1655-9. PMID 21856995 DOI: 10.1093/Carcin/Bgr187  0.388
2011 Lin DW, FitzGerald LM, Fu R, Kwon EM, Zheng SL, Kolb S, Wiklund F, Stattin P, Isaacs WB, Xu J, Ostrander EA, Feng Z, Grönberg H, Stanford JL. Genetic variants in the LEPR, CRY1, RNASEL, IL4, and ARVCF genes are prognostic markers of prostate cancer-specific mortality. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 1928-36. PMID 21846818 DOI: 10.1158/1055-9965.Epi-11-0236  0.633
2011 Sutcliffe S, Nevin RL, Pakpahan R, Elliott DJ, Cole SR, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Cersovsky SB, Platz EA. Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration. British Journal of Cancer. 105: 602-5. PMID 21792196 DOI: 10.1038/Bjc.2011.271  0.536
2011 Toubaji A, Albadine R, Meeker AK, Isaacs WB, Lotan T, Haffner MC, Chaux A, Epstein JI, Han M, Walsh PC, Partin AW, De Marzo AM, Platz EA, Netto GJ. Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 1511-20. PMID 21743434 DOI: 10.1038/Modpathol.2011.111  0.681
2011 Schumacher FR, Berndt SI, Siddiq A, Jacobs KB, Wang Z, Lindstrom S, Stevens VL, Chen C, Mondul AM, Travis RC, Stram DO, Eeles RA, Easton DF, Giles G, Hopper JL, ... ... Isaacs WB, et al. Genome-wide association study identifies new prostate cancer susceptibility loci. Human Molecular Genetics. 20: 3867-75. PMID 21743057 DOI: 10.1093/Hmg/Ddr295  0.449
2011 Haiman CA, Chen GK, Blot WJ, Strom SS, Berndt SI, Kittles RA, Rybicki BA, Isaacs WB, Ingles SA, Stanford JL, Diver WR, Witte JS, Chanock SJ, Kolb S, Signorello LB, et al. Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans. Plos Genetics. 7: e1001387. PMID 21637779 DOI: 10.1371/Journal.Pgen.1001387  0.618
2011 Xie CC, Lu L, Sun J, Zheng SL, Isaacs WB, Gronberg H, Xu J. Germ-line sequence variants of PTEN do not have an important role in hereditary and non-hereditary prostate cancer susceptibility. Journal of Human Genetics. 56: 496-502. PMID 21633361 DOI: 10.1038/Jhg.2011.48  0.555
2011 Haiman CA, Chen GK, Blot WJ, Strom SS, Berndt SI, Kittles RA, Rybicki BA, Isaacs WB, Ingles SA, Stanford JL, Diver WR, Witte JS, Hsing AW, Nemesure B, Rebbeck TR, et al. Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nature Genetics. 43: 570-3. PMID 21602798 DOI: 10.1038/Ng.839  0.57
2011 Berndt SI, Sampson J, Yeager M, Jacobs KB, Wang Z, Hutchinson A, Chung C, Orr N, Wacholder S, Chatterjee N, Yu K, Kraft P, Feigelson HS, Thun MJ, Diver WR, ... ... Isaacs W, et al. Large-scale fine mapping of the HNF1B locus and prostate cancer risk. Human Molecular Genetics. 20: 3322-9. PMID 21576123 DOI: 10.1093/Hmg/Ddr213  0.486
2011 Catalona WJ, Bailey-Wilson JE, Camp NJ, Chanock SJ, Cooney KA, Easton DF, Eeles RA, FitzGerald LM, Freedman ML, Gudmundsson J, Kittles RA, Margulies EH, McGuire BB, Ostrander EA, Rebbeck TR, ... ... Isaacs WB, et al. National Cancer Institute Prostate Cancer Genetics Workshop. Cancer Research. 71: 3442-6. PMID 21558387 DOI: 10.1158/0008-5472.Can-11-0314  0.596
2011 Jin G, Sun J, Liu W, Zhang Z, Chu LW, Kim ST, Sun J, Feng J, Duggan D, Carpten JD, Wiklund F, Grönberg H, Isaacs WB, Zheng SL, Xu J. Genome-wide copy-number variation analysis identifies common genetic variants at 20p13 associated with aggressiveness of prostate cancer. Carcinogenesis. 32: 1057-62. PMID 21551127 DOI: 10.1093/Carcin/Bgr082  0.502
2011 Lu Y, Zhang Z, Yu H, Zheng SL, Isaacs WB, Xu J, Sun J. Functional annotation of risk loci identified through genome-wide association studies for prostate cancer. The Prostate. 71: 955-63. PMID 21541972 DOI: 10.1002/Pros.21311  0.503
2011 Chung CC, Ciampa J, Yeager M, Jacobs KB, Berndt SI, Hayes RB, Gonzalez-Bosquet J, Kraft P, Wacholder S, Orr N, Yu K, Hutchinson A, Boland J, Chen Q, Feigelson HS, ... ... Isaacs WB, et al. Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer. Human Molecular Genetics. 20: 2869-78. PMID 21531787 DOI: 10.1093/Hmg/Ddr189  0.348
2011 Hu R, Isaacs WB, Luo J. A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities. The Prostate. 71: 1656-67. PMID 21446008 DOI: 10.1002/Pros.21382  0.502
2011 Wilson BA, Wang H, Nacev BA, Mease RC, Liu JO, Pomper MG, Isaacs WB. High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S). Molecular Cancer Therapeutics. 10: 825-38. PMID 21441411 DOI: 10.1158/1535-7163.Mct-10-0902  0.833
2011 Ahn J, Kibel AS, Park JY, Rebbeck TR, Rennert H, Stanford JL, Ostrander EA, Chanock S, Wang MH, Mittal RD, Isaacs WB, Platz EA, Hayes RB. Prostate cancer predisposition loci and risk of metastatic disease and prostate cancer recurrence. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1075-81. PMID 21343373 DOI: 10.1158/1078-0432.Ccr-10-0881  0.641
2011 Aly M, Wiklund F, Xu J, Isaacs WB, Eklund M, D'Amato M, Adolfsson J, Grönberg H. Polygenic risk score improves prostate cancer risk prediction: results from the Stockholm-1 cohort study. European Urology. 60: 21-8. PMID 21295399 DOI: 10.1016/J.Eururo.2011.01.017  0.631
2011 Chang BL, Spangler E, Gallagher S, Haiman CA, Henderson B, Isaacs W, Benford ML, Kidd LR, Cooney K, Strom S, Ingles SA, Stern MC, Corral R, Joshi AD, Xu J, et al. Validation of genome-wide prostate cancer associations in men of African descent. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 23-32. PMID 21071540 DOI: 10.1158/1055-9965.Epi-10-0698  0.584
2011 Fujita K, Ewing CM, Isaacs WB, Pavlovich CP. Immunomodulatory IL-18 binding protein is produced by prostate cancer cells and its levels in urine and serum correlate with tumor status. International Journal of Cancer. 129: 424-32. PMID 20878981 DOI: 10.1002/Ijc.25705  0.502
2011 Sun J, Kader AK, Hsu FC, Kim ST, Zhu Y, Turner AR, Jin T, Zhang Z, Adolfsson J, Wiklund F, Zheng SL, Isaacs WB, Grönberg H, Xu J. Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer. The Prostate. 71: 421-30. PMID 20878950 DOI: 10.1002/Pros.21256  0.437
2011 Sutcliffe S, Sokoll LJ, Walsh PC, Zenilman JM, Cersovsky SB, Nevin RL, Pakpahan R, Elliott DJ, Stephen CR, Marzo AMD, Gaydos CA, Isaacs WB, Nelson WG. Abstract A96: The influence of infectious mononucleosis on prostate-specific antigen concentration as a marker of prostate involvement during infection Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-A96  0.588
2011 Hu R, Isaacs WB, Luo J. Abstract LB-31: A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-31  0.512
2011 Cheng Y, Liu W, Sun J, Kim S, Lu L, Sun J, Zheng S, Isaacs WB, Xu J. Abstract 2769: Evaluation of PPP2R2A as a prostate cancer susceptibility gene: Comprehensive germline and somatic study Cancer Research. 71: 2769-2769. DOI: 10.1158/1538-7445.Am2011-2769  0.596
2011 Loeb S, Isaacs WB. Genetic basis for prostate cancer Recent Advances in Prostate Cancer: Basic Science Discoveries and Clinical Advances. 39-52. DOI: 10.1142/9789814329460_0002  0.54
2011 Hyndman M, Xu J, Zheng S, Isaacs W, Pavlovich C. 1203 THE BCL-2 -938 C GENOTYPE IS MORE PREVALENT IN PATIENTS WITH AGGRESSIVE DISEASE AND A FAMILY HISTORY OF PROSTATE CANCER Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.838  0.542
2010 Aloia AL, Sfanos KS, Isaacs WB, Zheng Q, Maldarelli F, De Marzo AM, Rein A. XMRV: a new virus in prostate cancer? Cancer Research. 70: 10028-33. PMID 20966126 DOI: 10.1158/0008-5472.Can-10-2837  0.7
2010 Chen H, Liu W, Roberts W, Hooker S, Fedor H, DeMarzo A, Isaacs W, Kittles RA. 8q24 allelic imbalance and MYC gene copy number in primary prostate cancer. Prostate Cancer and Prostatic Diseases. 13: 238-43. PMID 20634801 DOI: 10.1038/Pcan.2010.20  0.472
2010 Haffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, Isaacs WB, Bova GS, Liu W, Xu J, Meeker AK, Netto G, De Marzo AM, Nelson WG, Yegnasubramanian S. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nature Genetics. 42: 668-75. PMID 20601956 DOI: 10.1038/Ng.613  0.738
2010 Kim ST, Cheng Y, Hsu FC, Jin T, Kader AK, Zheng SL, Isaacs WB, Xu J, Sun J. Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation. The Prostate. 70: 1729-38. PMID 20564319 DOI: 10.1002/Pros.21208  0.497
2010 Elliott KS, Zeggini E, McCarthy MI, Gudmundsson J, Sulem P, Stacey SN, Thorlacius S, Amundadottir L, Grönberg H, Xu J, Gaborieau V, Eeles RA, Neal DE, Donovan JL, Hamdy FC, ... ... Isaacs WB, et al. Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies. Plos One. 5: e10858. PMID 20526366 DOI: 10.1371/Journal.Pone.0010858  0.555
2010 Prokunina-Olsson L, Fu YP, Tang W, Jacobs KB, Hayes RB, Kraft P, Berndt SI, Wacholder S, Yu K, Hutchinson A, Spencer Feigelson H, Thun MJ, Diver WR, Albanes D, Virtamo J, ... ... Isaacs WB, et al. Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 1349-55. PMID 20406958 DOI: 10.1158/1055-9965.Epi-09-1181  0.556
2010 Christensen GB, Baffoe-Bonnie AB, George A, Powell I, Bailey-Wilson JE, Carpten JD, Giles GG, Hopper JL, Severi G, English DR, Foulkes WD, Maehle L, Moller P, Eeles R, Easton D, ... ... Isaacs WB, et al. Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses. The Prostate. 70: 735-44. PMID 20333727 DOI: 10.1002/Pros.21106  0.479
2010 Hsu FC, Sun J, Zhu Y, Kim ST, Jin T, Zhang Z, Wiklund F, Kader AK, Zheng SL, Isaacs W, Grönberg H, Xu J. Comparison of two methods for estimating absolute risk of prostate cancer based on single nucleotide polymorphisms and family history. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 1083-8. PMID 20332264 DOI: 10.1158/1055-9965.Epi-09-1176  0.392
2010 Xu J, Zheng SL, Isaacs SD, Wiley KE, Wiklund F, Sun J, Kader AK, Li G, Purcell LD, Kim ST, Hsu FC, Stattin P, Hugosson J, Adolfsson J, Walsh PC, ... ... Isaacs WB, et al. Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 107: 2136-40. PMID 20080650 DOI: 10.1073/Pnas.0914061107  0.5
2010 Lubahn J, Berndt SI, Jin CH, Klim A, Luly J, Wu WS, Isaacs S, Wiley K, Isaacs WB, Suarez BK, Hayes RB, Kibel AS. Association of CASP8 D302H polymorphism with reduced risk of aggressive prostate carcinoma. The Prostate. 70: 646-53. PMID 20033885 DOI: 10.1002/Pros.21098  0.518
2010 Fujita K, Ewing CM, Getzenberg RH, Parsons JK, Isaacs WB, Pavlovich CP. Monocyte chemotactic protein-1 (MCP-1/CCL2) is associated with prostatic growth dysregulation and benign prostatic hyperplasia. The Prostate. 70: 473-81. PMID 19902472 DOI: 10.1002/Pros.21081  0.581
2010 Zheng SL, Hsing AW, Sun J, Chu LW, Yu K, Li G, Gao Z, Kim ST, Isaacs WB, Shen MC, Gao YT, Hoover RN, Xu J. Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men. The Prostate. 70: 425-32. PMID 19866473 DOI: 10.1002/Pros.21076  0.632
2010 Nelson WG, Haffner MC, Aryee MJ, Esopi DM, Isaacs WB, Bova GS, Meeker AK, Netto G, Marzo AMD, Yegnasubramanian S. Abstract CN05-04: Early molecular changes in prostate carcinogenesis Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn05-04  0.773
2010 Chung CC, Ciampa J, Yeager M, Jacobs KB, Hayes RB, Deng Z, Gonzalez-Bosquet J, Kraft P, Sonja BI, Sholom W, Orr N, Yu K, Hutchinson A, Feigelson HS, Thun MJ, ... ... Isaacs WB, et al. Abstract 3863: Fine mapping and comprehensive resequencing analysis of a region of chromosome 11q13 reveals multiple independent loci associated with prostate cancer Cancer Research. 70: 3863-3863. DOI: 10.1158/1538-7445.Am10-3863  0.369
2010 Grönberg H, Xu J, Isaacs W. 621 Individualized prediction of prostate cancer using genetic markers European Journal of Cancer Supplements. 8: 158. DOI: 10.1016/s1359-6349(10)71422-1  0.497
2010 Xu J, Sun J, Kim S, Kader AK, Walsh P, Partin A, Gronberg H, Zheng S, Isaacs W. 2151 ASSOCIATION OF PROSTATE CANCER RISK SNPS WITH AGE AT TREATMENT: POTENTIAL FOR PREDICTION OF EARLY ONSET OF DISEASE Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.2253  0.532
2010 Schultz L, Platz E, Toubaji A, Albadine R, Hicks J, Isaacs W, McEvoy C, Meeker A, De Marzo A, Netto G. 2128 LOSS OF PTEN EXPRESSION IS AN INDEPENDENT PREDICTOR OF RECURRENCE IN PROSTATE CARCINOMA Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.2216  0.687
2009 Brown DA, Lindmark F, Stattin P, Bälter K, Adami HO, Zheng SL, Xu J, Isaacs WB, Grönberg H, Breit SN, Wiklund FE. Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6658-64. PMID 19843661 DOI: 10.1158/1078-0432.Ccr-08-3126  0.617
2009 Yeager M, Chatterjee N, Ciampa J, Jacobs KB, Gonzalez-Bosquet J, Hayes RB, Kraft P, Wacholder S, Orr N, Berndt S, Yu K, Hutchinson A, Wang Z, Amundadottir L, Feigelson HS, ... ... Isaacs W, et al. Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nature Genetics. 41: 1055-7. PMID 19767755 DOI: 10.1038/Ng.444  0.563
2009 Albadine R, Latour M, Toubaji A, Haffner M, Isaacs WB, A Platz E, Meeker AK, Demarzo AM, Epstein JI, Netto GJ. TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1415-22. PMID 19734849 DOI: 10.1038/Modpathol.2009.121  0.655
2009 Sfanos KS, Bruno TC, Meeker AK, De Marzo AM, Isaacs WB, Drake CG. Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. The Prostate. 69: 1694-703. PMID 19670224 DOI: 10.1002/Pros.21020  0.767
2009 Loeb S, Helfand BT, Kan D, Isaacs WB, Catalona WJ. Does diabetes mellitus modify the association between 17q12 risk variant and prostate cancer aggressiveness? Bju International. 104: 1200-3. PMID 19627283 DOI: 10.1111/J.1464-410X.2009.08656.X  0.6
2009 Xu J, Sun J, Kader AK, Lindström S, Wiklund F, Hsu FC, Johansson JE, Zheng SL, Thomas G, Hayes RB, Kraft P, Hunter DJ, Chanock SJ, Isaacs WB, Grönberg H. Estimation of absolute risk for prostate cancer using genetic markers and family history. The Prostate. 69: 1565-72. PMID 19562736 DOI: 10.1002/Pros.21002  0.435
2009 Lu L, Sun J, Isaacs SD, Wiley KE, Smith S, Pruett K, Zhu Y, Zhang Z, Wiklund F, Grönberg H, Walsh PC, Chang BL, Zheng SL, Isaacs WB, Xu J. Fine-mapping and family-based association analyses of prostate cancer risk variants at Xp11. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 2132-6. PMID 19549809 DOI: 10.1158/1055-9965.Epi-08-1221  0.475
2009 Xu J, Kibel AS, Hu JJ, Turner AR, Pruett K, Zheng SL, Sun J, Isaacs SD, Wiley KE, Kim ST, Hsu FC, Wu W, Torti FM, Walsh PC, Chang BL, ... Isaacs WB, et al. Prostate cancer risk associated loci in African Americans. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 2145-9. PMID 19549807 DOI: 10.1158/1055-9965.Epi-09-0091  0.502
2009 Zheng SL, Stevens VL, Wiklund F, Isaacs SD, Sun J, Smith S, Pruett K, Wiley KE, Kim ST, Zhu Y, Zhang Z, Hsu FC, Turner AR, Johansson JE, Liu W, ... ... Isaacs W, et al. Two independent prostate cancer risk-associated Loci at 11q13. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1815-20. PMID 19505914 DOI: 10.1158/1055-9965.Epi-08-0983  0.58
2009 Loeb S, Carter HB, Walsh PC, Isaacs WB, Kettermann A, Tanaka T, Ferrucci L, Metter EJ. Single nucleotide polymorphisms and the likelihood of prostate cancer at a given prostate specific antigen level. The Journal of Urology. 182: 101-4; discussion 10. PMID 19450841 DOI: 10.1016/J.Juro.2009.02.126  0.631
2009 Kader AK, Sun J, Isaacs SD, Wiley KE, Yan G, Kim ST, Fedor H, DeMarzo AM, Epstein JI, Walsh PC, Partin AW, Trock B, Zheng SL, Xu J, Isaacs W. Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients. The Prostate. 69: 1195-205. PMID 19434657 DOI: 10.1002/Pros.20970  0.611
2009 Wiklund FE, Adami HO, Zheng SL, Stattin P, Isaacs WB, Grönberg H, Xu J. Established prostate cancer susceptibility variants are not associated with disease outcome. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1659-62. PMID 19423541 DOI: 10.1158/1055-9965.Epi-08-1148  0.659
2009 Fujita K, Pavlovich CP, Netto GJ, Konishi Y, Isaacs WB, Ali S, De Marzo A, Meeker AK. Specific detection of prostate cancer cells in urine by multiplex immunofluorescence cytology. Human Pathology. 40: 924-33. PMID 19368959 DOI: 10.1016/J.Humpath.2009.01.004  0.759
2009 Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, ... Isaacs WB, et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nature Medicine. 15: 559-65. PMID 19363497 DOI: 10.1038/Nm.1944  0.595
2009 Hsu FC, Sun J, Wiklund F, Isaacs SD, Wiley KE, Purcell LD, Gao Z, Stattin P, Zhu Y, Kim ST, Zhang Z, Liu W, Chang BL, Walsh PC, Duggan D, ... ... Isaacs WB, et al. A novel prostate cancer susceptibility locus at 19q13. Cancer Research. 69: 2720-3. PMID 19318570 DOI: 10.1158/0008-5472.Can-08-3347  0.442
2009 Wang MH, Helzlsouer KJ, Smith MW, Hoffman-Bolton JA, Clipp SL, Grinberg V, De Marzo AM, Isaacs WB, Drake CG, Shugart YY, Platz EA. Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II Prostate. 69: 874-885. PMID 19267370 DOI: 10.1002/Pros.20933  0.504
2009 Liu W, Sun J, Li G, Zhu Y, Zhang S, Kim ST, Sun J, Wiklund F, Wiley K, Isaacs SD, Stattin P, Xu J, Duggan D, Carpten JD, Isaacs WB, et al. Association of a germ-line copy number variation at 2p24.3 and risk for aggressive prostate cancer. Cancer Research. 69: 2176-9. PMID 19258504 DOI: 10.1158/0008-5472.Can-08-3151  0.602
2009 Sfanos KS, Wilson BA, De Marzo AM, Isaacs WB. Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 106: 3443-8. PMID 19202053 DOI: 10.1073/Pnas.0810473106  0.845
2009 Zheng SL, Sun J, Wiklund F, Gao Z, Stattin P, Purcell LD, Adami HO, Hsu FC, Zhu Y, Adolfsson J, Johansson JE, Turner AR, Adams TS, Liu W, Duggan D, ... ... Isaacs WB, et al. Genetic variants and family history predict prostate cancer similar to prostate-specific antigen. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1105-11. PMID 19188186 DOI: 10.1158/1078-0432.Ccr-08-1743  0.649
2009 Chang BL, Cramer SD, Wiklund F, Isaacs SD, Stevens VL, Sun J, Smith S, Pruett K, Romero LM, Wiley KE, Kim ST, Zhu Y, Zhang Z, Hsu FC, Turner AR, ... ... Isaacs WB, et al. Fine mapping association study and functional analysis implicate a SNP in MSMB at 10q11 as a causal variant for prostate cancer risk. Human Molecular Genetics. 18: 1368-75. PMID 19153072 DOI: 10.1093/Hmg/Ddp035  0.574
2009 Parsons JK, Saria EA, Nakayama M, Vessella RL, Sawyers CL, Isaacs WB, Faith DA, Bova GS, Samathanam CA, Mitchell R, De Marzo AM. Comprehensive mutational analysis and mRNA isoform quantification of TP63 in normal and neoplastic human prostate cells. The Prostate. 69: 559-69. PMID 19142959 DOI: 10.1002/Pros.20904  0.64
2009 Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, Han M, Partin AW, Vessella RL, Isaacs WB, Bova GS, Luo J. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Research. 69: 16-22. PMID 19117982 DOI: 10.1158/0008-5472.Can-08-2764  0.523
2009 Sun J, Zheng SL, Wiklund F, Isaacs SD, Li G, Wiley KE, Kim ST, Zhu Y, Zhang Z, Hsu FC, Turner AR, Stattin P, Liu W, Kim JW, Duggan D, ... ... Isaacs W, et al. Sequence variants at 22q13 are associated with prostate cancer risk. Cancer Research. 69: 10-5. PMID 19117981 DOI: 10.1158/0008-5472.Can-08-3464  0.565
2009 Wiklund F, Zheng SL, Sun J, Adami HO, Lilja H, Hsu FC, Stattin P, Adolfsson J, Cramer SD, Duggan D, Carpten JD, Chang BL, Isaacs WB, Grönberg H, Xu J. Association of reported prostate cancer risk alleles with PSA levels among men without a diagnosis of prostate cancer. The Prostate. 69: 419-27. PMID 19116992 DOI: 10.1002/Pros.20908  0.641
2009 Cheng Y, Kim JW, Liu W, Dunn TA, Luo J, Loza MJ, Kim ST, Zheng SL, Xu J, Isaacs WB, Chang BL. Genetic and epigenetic inactivation of TNFRSF10C in human prostate cancer. The Prostate. 69: 327-35. PMID 19035483 DOI: 10.1002/Pros.20882  0.629
2009 Fujita K, Ewing CM, Chan DY, Mangold LA, Partin AW, Isaacs WB, Pavlovich CP. Endoglin (CD105) as a urinary and serum marker of prostate cancer. International Journal of Cancer. 124: 664-9. PMID 19004009 DOI: 10.1002/Ijc.24007  0.627
2009 Dunn TA, Fedor H, Isaacs WB, De Marzo AM, Luo J. Genome-wide expression analysis of recently processed formalin-fixed paraffin embedded human prostate tissues. The Prostate. 69: 214-8. PMID 18973134 DOI: 10.1002/Pros.20863  0.449
2009 Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, ... Isaacs WB, et al. Erratum: Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer Nature Medicine. 15: 819-819. DOI: 10.1038/Nm0709-819A  0.637
2009 Xu J, Sun J, Kader AK, Lindström S, Wiklund F, Hsu F, Kim S, Johansson J, Zheng SL, Platz EA, Isaacs WB, Grönberg H. ESTIMATION OF ABSOLUTE RISK FOR PROSTATE CANCER FROM BLOOD DNA The Journal of Urology. 181: 643. DOI: 10.1016/S0022-5347(09)61807-3  0.534
2009 Parsons JK, Fujita K, Ewing CM, Isaacs WB, Pavlovich CP. PROSTATIC MONOCYTE CHEMOTACTIC PROTEIN-1 (MCP-1): A NOVEL BIOMARKER FOR LOWER URINARY TRACT SYMPTOMS ASSOCIATED WITH BENIGN PROSTATIC HYPERPLASIA The Journal of Urology. 181: 595. DOI: 10.1016/S0022-5347(09)61674-8  0.579
2009 Fujita K, Ewing CM, Getzenberg RH, Parsons JK, Isaacs WB, Pavlovich CP. MONOCYTE CHEMOTACTIC PROTEIN-1 (MCP-1:CCL2) IS ASSOCIATED WITH PROSTATIC GROWTH DYSREGULATION Journal of Urology. 181: 505-506. DOI: 10.1016/S0022-5347(09)61427-0  0.533
2009 Wang M, Zheng SL, De Marzo AM, Drake CG, Fedor HL, Partin AW, Han M, Xu J, Isaacs WB, Platz EA. VARIANTS IN GENES INVOLVED IN THE IMMUNE RESPONSE AND OXIDATION AND SUBSEQUENT RISK OF PROSTATE CANCER RECURRENCE Journal of Urology. 181: 167-168. DOI: 10.1016/S0022-5347(09)60481-X  0.543
2009 Loeb S, Helfand BT, Kan D, Isaacs WB, Catalona WJ. ARE DIABETES MELLITUS AND CHROMOSOME 17Q12 GENETIC VARIANTS ASSOCIATED WITH PROSTATE CANCER AGGRESSIVENESS? Journal of Urology. 181: 102-102. DOI: 10.1016/S0022-5347(09)60292-5  0.595
2009 Sutcliffe S, Nevin RL, Pakpahan RM, Bruzek DJ, Cole SR, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Cersovsky SB, Platz EA. PROSTATE INVOLVEMENT DURING SEXUALLY TRANSMITTED INFECTIONS AS MEASURED BY PROSTATE SPECIFIC ANTIGEN CONCENTRATION Journal of Urology. 181: 64-64. DOI: 10.1016/S0022-5347(09)60189-0  0.453
2009 Kader A, Sun J, Fedor H, DeMarzo A, Epstein J, Walsh P, Partin A, Zheng S, Xu J, Isaacs W. POD-02.10: Individual and Cumulative Effect of Prostate Cancer Risk-associated Variants on Clinicopathologic Variables in 5,895 Prostate Cancer Patients Urology. 74: S7-S8. DOI: 10.1016/J.Urology.2009.07.1204  0.636
2009 Xu J, Sun J, Kader A, Lindstrom S, Wiklund F, Hsu F, Johansson J, Zheng S, Isaacs W, Gronberg H. POD-02.09: Estimation of Absolute Risk for Prostate Cancer from Blood DNA Urology. 74: S7. DOI: 10.1016/J.Urology.2009.07.1203  0.533
2008 Kim JW, Cheng Y, Liu W, Li T, Yegnasubramanian S, Zheng SL, Xu J, Isaacs WB, Chang BL. Genetic and epigenetic inactivation of LPL gene in human prostate cancer. International Journal of Cancer. 124: 734-8. PMID 19004026 DOI: 10.1002/Ijc.23972  0.578
2008 Yegnasubramanian S, Haffner MC, Zhang Y, Gurel B, Cornish TC, Wu Z, Irizarry RA, Morgan J, Hicks J, DeWeese TL, Isaacs WB, Bova GS, De Marzo AM, Nelson WG. DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Research. 68: 8954-67. PMID 18974140 DOI: 10.1158/0008-5472.Can-07-6088  0.631
2008 Xu J, Isaacs SD, Sun J, Li G, Wiley KE, Zhu Y, Hsu FC, Wiklund F, Turner AR, Adams TS, Liu W, Trock BJ, Partin AW, Chang B, Walsh PC, ... ... Isaacs W, et al. Association of prostate cancer risk variants with clinicopathologic characteristics of the disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5819-24. PMID 18794092 DOI: 10.1158/1078-0432.Ccr-08-0934  0.629
2008 Lange EM, Sun J, Lange LA, Zheng SL, Duggan D, Carpten JD, Gronberg H, Isaacs WB, Xu J, Chang BL. Family-based samples can play an important role in genetic association studies. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 2208-14. PMID 18768484 DOI: 10.1158/1055-9965.Epi-08-0183  0.342
2008 Sun J, Zheng SL, Wiklund F, Isaacs SD, Purcell LD, Gao Z, Hsu FC, Kim ST, Liu W, Zhu Y, Stattin P, Adami HO, Wiley KE, Dimitrov L, Sun J, ... ... Isaacs WB, et al. Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nature Genetics. 40: 1153-5. PMID 18758462 DOI: 10.1038/Ng.214  0.482
2008 Liu W, Xie CC, Zhu Y, Li T, Sun J, Cheng Y, Ewing CM, Dalrymple S, Turner AR, Sun J, Isaacs JT, Chang BL, Zheng SL, Isaacs WB, Xu J. Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer. Neoplasia (New York, N.Y.). 10: 897-907. PMID 18670647 DOI: 10.1593/Neo.08428  0.646
2008 Sfanos KS, Isaacs WB. An evaluation of PCR primer sets used for detection of Propionibacterium acnes in prostate tissue samples. The Prostate. 68: 1492-5. PMID 18651578 DOI: 10.1002/Pros.20820  0.678
2008 Tischkowitz MD, Yilmaz A, Chen LQ, Karyadi DM, Novak D, Kirchhoff T, Hamel N, Tavtigian SV, Kolb S, Bismar TA, Aloyz R, Nelson PS, Hood L, Narod SA, White KA, ... ... Isaacs WB, et al. Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. Cancer Letters. 270: 173-80. PMID 18571837 DOI: 10.1016/J.Canlet.2008.05.006  0.569
2008 Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, Hicks JL, Morgan J, Cornish TC, Sutcliffe S, Isaacs WB, Luo J, De Marzo AM. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 1156-67. PMID 18567993 DOI: 10.1038/Modpathol.2008.111  0.581
2008 Inge LJ, Rajasekaran SA, Wolle D, Barwe SP, Ryazantsev S, Ewing CM, Isaacs WB, Rajasekaran AK. alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling. Molecular Cancer Therapeutics. 7: 1386-97. PMID 18566211 DOI: 10.1158/1535-7163.Mct-07-2029  0.381
2008 Wei S, Dunn TA, Isaacs WB, De Marzo AM, Luo J. GOLPH2 and MYO6: putative prostate cancer markers localized to the Golgi apparatus. The Prostate. 68: 1387-95. PMID 18543251 DOI: 10.1002/Pros.20806  0.594
2008 Sfanos KS, Bruno TC, Maris CH, Xu L, Thoburn CJ, DeMarzo AM, Meeker AK, Isaacs WB, Drake CG. Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3254-61. PMID 18519750 DOI: 10.1158/1078-0432.Ccr-07-5164  0.824
2008 Hsu FC, Lindström S, Sun J, Wiklund F, Chen SH, Adami HO, Turner AR, Liu W, Bälter K, Kim JW, Stattin P, Chang BL, Isaacs WB, Xu J, Grönberg H, et al. A multigenic approach to evaluating prostate cancer risk in a systematic replication study. Cancer Genetics and Cytogenetics. 183: 94-8. PMID 18503826 DOI: 10.1016/J.Cancergencyto.2008.02.008  0.6
2008 Sun J, Chang BL, Isaacs SD, Wiley KE, Wiklund F, Stattin P, Duggan D, Carpten JD, Trock BJ, Partin AW, Walsh PC, Grönberg H, Xu J, Isaacs WB, Zheng SL. Cumulative effect of five genetic variants on prostate cancer risk in multiple study populations. The Prostate. 68: 1257-62. PMID 18491292 DOI: 10.1002/Pros.20793  0.587
2008 Sun J, Purcell L, Gao Z, Isaacs SD, Wiley KE, Hsu FC, Liu W, Duggan D, Carpten JD, Grönberg H, Xu J, Chang BL, Partin AW, Walsh PC, Isaacs WB, et al. Association between sequence variants at 17q12 and 17q24.3 and prostate cancer risk in European and African Americans. The Prostate. 68: 691-7. PMID 18361410 DOI: 10.1002/Pros.20754  0.519
2008 Fujita K, Ewing CM, Sokoll LJ, Elliott DJ, Cunningham M, De Marzo AM, Isaacs WB, Pavlovich CP. Cytokine profiling of prostatic fluid from cancerous prostate glands identifies cytokines associated with extent of tumor and inflammation. The Prostate. 68: 872-82. PMID 18361406 DOI: 10.1002/Pros.20755  0.643
2008 Gudmundsson J, Sulem P, Rafnar T, Bergthorsson JT, Manolescu A, Gudbjartsson D, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Blondal T, Jakobsdottir M, Stacey SN, Kostic J, Kristinsson KT, Birgisdottir B, ... ... Isaacs WB, et al. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nature Genetics. 40: 281-3. PMID 18264098 DOI: 10.1038/Ng.89  0.558
2008 Sun J, Lange EM, Isaacs SD, Liu W, Wiley KE, Lange L, Gronberg H, Duggan D, Carpten JD, Walsh PC, Xu J, Chang BL, Isaacs WB, Zheng SL. Chromosome 8q24 risk variants in hereditary and non-hereditary prostate cancer patients. The Prostate. 68: 489-97. PMID 18213635 DOI: 10.1002/Pros.20695  0.607
2008 Zheng SL, Sun J, Wiklund F, Smith S, Stattin P, Li G, Adami HO, Hsu FC, Zhu Y, Bälter K, Kader AK, Turner AR, Liu W, Bleecker ER, Meyers DA, ... ... Isaacs WB, et al. Cumulative association of five genetic variants with prostate cancer. The New England Journal of Medicine. 358: 910-9. PMID 18199855 DOI: 10.1056/Nejmoa075819  0.534
2008 Sfanos KS, Sauvageot J, Fedor HL, Dick JD, De Marzo AM, Isaacs WB. A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms. The Prostate. 68: 306-20. PMID 18163428 DOI: 10.1002/Pros.20680  0.78
2008 Freedland SJ, Mavropoulos J, Wang A, Darshan M, Demark-Wahnefried W, Aronson WJ, Cohen P, Hwang D, Peterson B, Fields T, Pizzo SV, Isaacs WB. Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis. The Prostate. 68: 11-9. PMID 17999389 DOI: 10.1002/Pros.20683  0.311
2008 Fujita K, Ewing CM, Chan D, Magnold L, Partin AW, Getzenberg RH, Isaacs WB, Pavlovich CP. ENDOGLIN (CD105) AS A POTENTIAL URINARY MARKER FOR PROSTATE CANCER DETECTION Journal of Urology. 179: 720-720. DOI: 10.1016/S0022-5347(08)62099-6  0.551
2008 Xu J, Zheng SL, Wiklund F, Sun J, Chang B, Adami H, Partin AW, Walsh PC, Gronberg H, Isaacs WB. COMBINATION OF FIVE SNPs PREDICTS INDIVIDUAL RISK FOR PROSTATE CANCER Journal of Urology. 179: 706-707. DOI: 10.1016/S0022-5347(08)62058-3  0.572
2008 Roberts WB, Dunn TA, Ahaghotu CA, Kittles R, Freedland SJ, Isaacs WB, Luo J. DIFFERENTIAL GENE EXPRESSION IN HUMAN PROSTATE CANCER BASED ON ETHNIC OR GEOGRAPHIC ORIGIN Journal of Urology. 179: 226-226. DOI: 10.1016/S0022-5347(08)60652-7  0.588
2007 Duggan D, Zheng SL, Knowlton M, Benitez D, Dimitrov L, Wiklund F, Robbins C, Isaacs SD, Cheng Y, Li G, Sun J, Chang BL, Marovich L, Wiley KE, Bälter K, ... ... Isaacs WB, et al. Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. Journal of the National Cancer Institute. 99: 1836-44. PMID 18073375 DOI: 10.1093/Jnci/Djm250  0.639
2007 Zheng SL, Sun J, Cheng Y, Li G, Hsu FC, Zhu Y, Chang BL, Liu W, Kim JW, Turner AR, Gielzak M, Yan G, Isaacs SD, Wiley KE, Sauvageot J, ... ... Isaacs WB, et al. Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans. Journal of the National Cancer Institute. 99: 1525-33. PMID 17925536 DOI: 10.1093/Jnci/Djm169  0.544
2007 Liu W, Chang BL, Cramer S, Koty PP, Li T, Sun J, Turner AR, Von Kap-Herr C, Bobby P, Rao J, Zheng SL, Isaacs WB, Xu J. Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5028-33. PMID 17785553 DOI: 10.1158/1078-0432.Ccr-07-0300  0.568
2007 Sutcliffe S, Giovannucci E, Isaacs WB, Willett WC, Platz EA. Acne and risk of prostate cancer. International Journal of Cancer. Journal International Du Cancer. 121: 2688-92. PMID 17724724 DOI: 10.1002/Ijc.23032  0.622
2007 Daugherty SE, Platz EA, Shugart YY, Fallin MD, Isaacs WB, Chatterjee N, Welch R, Huang WY, Hayes RB. Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1536-42. PMID 17684125 DOI: 10.1158/1055-9965.Epi-07-0117  0.414
2007 Daugherty SE, Shugart YY, Platz EA, Fallin MD, Isaacs WB, Pfeiffer RM, Welch R, Huang WY, Reding D, Hayes RB. Polymorphic variants in alpha-methylacyl-CoA racemase and prostate cancer. The Prostate. 67: 1487-97. PMID 17680641 DOI: 10.1002/Pros.20635  0.655
2007 Liu W, Ewing CM, Chang BL, Li T, Sun J, Turner AR, Dimitrov L, Zhu Y, Sun J, Kim JW, Zheng SL, Isaacs WB, Xu J. Multiple genomic alterations on 21q22 predict various TMPRSS2/ERG fusion transcripts in human prostate cancers. Genes, Chromosomes & Cancer. 46: 972-80. PMID 17654723 DOI: 10.1002/Gcc.20482  0.466
2007 Langeberg WJ, Isaacs WB, Stanford JL. Genetic etiology of hereditary prostate cancer. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4101-10. PMID 17485361 DOI: 10.2741/2374  0.526
2007 Chang BL, Liu W, Sun J, Dimitrov L, Li T, Turner AR, Zheng SL, Isaacs WB, Xu J. Integration of somatic deletion analysis of prostate cancers and germline linkage analysis of prostate cancer families reveals two small consensus regions for prostate cancer genes at 8p. Cancer Research. 67: 4098-103. PMID 17483320 DOI: 10.1158/0008-5472.Can-06-4570  0.56
2007 Sun J, Turner A, Xu J, Grönberg H, Isaacs W. Genetic variability in inflammation pathways and prostate cancer risk. Urologic Oncology. 25: 250-9. PMID 17483024 DOI: 10.1016/J.Urolonc.2006.10.001  0.581
2007 Camp NJ, Cannon-Albright LA, Farnham JM, Baffoe-Bonnie AB, George A, Powell I, Bailey-Wilson JE, Carpten JD, Giles GG, Hopper JL, Severi G, English DR, Foulkes WD, Maehle L, Moller P, ... ... Isaacs WB, et al. Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics. Human Molecular Genetics. 16: 1271-8. PMID 17478474 DOI: 10.1093/Hmg/Ddm075  0.488
2007 Carnell AJ, Hale I, Denis S, Wanders RJ, Isaacs WB, Wilson BA, Ferdinandusse S. Design, synthesis, and in vitro testing of alpha-methylacyl-CoA racemase inhibitors. Journal of Medicinal Chemistry. 50: 2700-7. PMID 17477519 DOI: 10.1021/Jm0702377  0.784
2007 Daugherty SE, Hayes RB, Yeager M, Andriole GL, Chatterjee N, Huang WY, Isaacs WB, Platz EA. RNASEL Arg462Gln polymorphism and prostate cancer in PLCO. The Prostate. 67: 849-54. PMID 17407163 DOI: 10.1002/Pros.20537  0.643
2007 Gudmundsson J, Sulem P, Manolescu A, Amundadottir LT, Gudbjartsson D, Helgason A, Rafnar T, Bergthorsson JT, Agnarsson BA, Baker A, Sigurdsson A, Benediktsdottir KR, Jakobsdottir M, Xu J, Blondal T, ... ... Isaacs WB, et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nature Genetics. 39: 631-7. PMID 17401366 DOI: 10.1038/Ng1999  0.562
2007 De Marzo AM, Platz EA, Sutcliffe S, Xu J, Grönberg H, Drake CG, Nakai Y, Isaacs WB, Nelson WG. Inflammation in prostate carcinogenesis. Nature Reviews. Cancer. 7: 256-69. PMID 17384581 DOI: 10.1038/Nrc2090  0.555
2007 Kouprina N, Noskov VN, Solomon G, Otstot J, Isaacs W, Xu J, Schleutker J, Larionov V. Mutational analysis of SPANX genes in families with X-linked prostate cancer. The Prostate. 67: 820-8. PMID 17373721 DOI: 10.1002/Pros.20561  0.5
2007 Sun J, Liu W, Adams TS, Sun J, Li X, Turner AR, Chang B, Kim JW, Zheng SL, Isaacs WB, Xu J. DNA copy number alterations in prostate cancers: a combined analysis of published CGH studies. The Prostate. 67: 692-700. PMID 17342750 DOI: 10.1002/Pros.20543  0.493
2007 Lange EM, Robbins CM, Gillanders EM, Zheng SL, Xu J, Wang Y, White KA, Chang BL, Ho LA, Trent JM, Carpten JD, Isaacs WB, Cooney KA. Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis. Human Genetics. 121: 49-55. PMID 17120048 DOI: 10.1007/S00439-006-0274-2  0.628
2007 Powell IJ, Baffoe-Bonnie A, Carpten J, Xu J, Isaacs WB. 453: Disparity and Similarity in Hereditary Prostate Cancer Among African Americans and European Americans: Largest Genome-Wide Linkage Studies Journal of Urology. 177: 152-152. DOI: 10.1016/S0022-5347(18)30706-7  0.54
2007 Freedland SJ, Mavropoulos J, Wang A, Darshan M, Demark-Wahnefried W, Pizzo S, Aronson WJ, Cohen P, Isaacs WB. 145: A No-Carbohydrate Diet Significantly Delays Prostate Cancer Growth in an Animal Model Journal of Urology. 177: 50-50. DOI: 10.1016/S0022-5347(18)30410-5  0.546
2006 Wang X, Wang F, Taniguchi K, Seelan RS, Wang L, Zarfas KE, McDonnell SK, Qian C, Pan K, Lu Y, Shridhar V, Couch FJ, Tindall DJ, Beebe-Dimmer JL, Cooney KA, ... Isaacs WB, et al. Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk. Cancer Research. 66: 10302-7. PMID 17079449 DOI: 10.1158/0008-5472.Can-06-0638  0.625
2006 Dunn TA, Chen S, Faith DA, Hicks JL, Platz EA, Chen Y, Ewing CM, Sauvageot J, Isaacs WB, De Marzo AM, Luo J. A novel role of myosin VI in human prostate cancer. The American Journal of Pathology. 169: 1843-54. PMID 17071605 DOI: 10.2353/Ajpath.2006.060316  0.639
2006 Lindström S, Zheng SL, Wiklund F, Jonsson BA, Adami HO, Bälter KA, Brookes AJ, Sun J, Chang BL, Liu W, Li G, Isaacs WB, Adolfsson J, Grönberg H, Xu J. Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway. The Prostate. 66: 1729-43. PMID 16998812 DOI: 10.1002/Pros.20489  0.634
2006 Schaid DJ, McDonnell SK, Zarfas KE, Cunningham JM, Hebbring S, Thibodeau SN, Eeles RA, Easton DF, Foulkes WD, Simard J, Giles GG, Hopper JL, Mahle L, Moller P, Badzioch M, ... ... Isaacs WB, et al. Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics. Human Genetics. 120: 471-85. PMID 16932970 DOI: 10.1007/s00439-006-0219-9  0.545
2006 Zheng SL, Liu W, Wiklund F, Dimitrov L, Bälter K, Sun J, Adami HO, Johansson JE, Sun J, Chang B, Loza M, Turner AR, Bleecker ER, Meyers DA, Carpten JD, ... ... Isaacs WB, et al. A comprehensive association study for genes in inflammation pathway provides support for their roles in prostate cancer risk in the CAPS study. The Prostate. 66: 1556-64. PMID 16921508 DOI: 10.1002/Pros.20496  0.624
2006 Liu W, Chang B, Sauvageot J, Dimitrov L, Gielzak M, Li T, Yan G, Sun J, Sun J, Adams TS, Turner AR, Kim JW, Meyers DA, Zheng SL, Isaacs WB, et al. Comprehensive assessment of DNA copy number alterations in human prostate cancers using Affymetrix 100K SNP mapping array. Genes, Chromosomes & Cancer. 45: 1018-32. PMID 16897747 DOI: 10.1002/Gcc.20369  0.559
2006 Mavropoulos JC, Isaacs WB, Pizzo SV, Freedland SJ. Is there a role for a low-carbohydrate ketogenic diet in the management of prostate cancer? Urology. 68: 15-8. PMID 16844447 DOI: 10.1016/J.Urology.2006.03.073  0.368
2006 Kidd LR, Coulibaly A, Templeton TM, Chen W, Long LO, Mason T, Bonilla C, Akereyeni F, Freeman V, Isaacs W, Ahaghotu C, Kittles RA. Germline BCL-2 sequence variants and inherited predisposition to prostate cancer. Prostate Cancer and Prostatic Diseases. 9: 284-92. PMID 16733517 DOI: 10.1038/Sj.Pcan.4500884  0.641
2006 Hebbring SJ, Fredriksson H, White KA, Maier C, Ewing C, McDonnell SK, Jacobsen SJ, Cerhan J, Schaid DJ, Ikonen T, Autio V, Tammela TL, Herkommer K, Paiss T, Vogel W, ... ... Isaacs W, et al. Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 935-8. PMID 16702373 DOI: 10.1158/1055-9965.Epi-05-0910  0.611
2006 Xu J, Sauvageot J, Ewing CM, Sun J, Liu W, Isaacs SD, Wiley KE, Diaz L, Zheng SL, Walsh PC, Isaacs WB. Germline ATBF1 mutations and prostate cancer risk. The Prostate. 66: 1082-5. PMID 16637072 DOI: 10.1002/Pros.20430  0.589
2006 Sutcliffe S, Zenilman JM, Ghanem KG, Jadack RA, Sokoll LJ, Elliott DJ, Nelson WG, De Marzo AM, Cole SR, Isaacs WB, Platz EA. Sexually transmitted infections and prostatic inflammation/cell damage as measured by serum prostate specific antigen concentration. The Journal of Urology. 175: 1937-42. PMID 16600802 DOI: 10.1016/S0022-5347(05)00892-X  0.532
2006 Sun J, Wiklund F, Hsu FC, Bälter K, Zheng SL, Johansson JE, Chang B, Liu W, Li T, Turner AR, Li L, Li G, Adami HO, Isaacs WB, Xu J, et al. Interactions of sequence variants in interleukin-1 receptor-associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 480-5. PMID 16537705 DOI: 10.1158/1055-9965.Epi-05-0645  0.608
2006 Sun J, Hsu FC, Turner AR, Zheng SL, Chang BL, Liu W, Isaacs WB, Xu J. Meta-analysis of association of rare mutations and common sequence variants in the MSR1 gene and prostate cancer risk. The Prostate. 66: 728-37. PMID 16425212 DOI: 10.1002/Pros.20396  0.615
2006 Gu Y, Li H, Miki J, Kim KH, Furusato B, Sesterhenn IA, Chu WS, McLeod DG, Srivastava S, Ewing CM, Isaacs WB, Rhim JS. Phenotypic characterization of telomerase-immortalized primary non-malignant and malignant tumor-derived human prostate epithelial cell lines. Experimental Cell Research. 312: 831-43. PMID 16413016 DOI: 10.1016/J.Yexcr.2005.11.029  0.589
2006 Zheng SL, Ju JH, Chang BL, Ortner E, Sun J, Isaacs SD, Sun J, Wiley KE, Liu W, Zemedkun M, Walsh PC, Ferretti J, Gruschus J, Isaacs WB, Gelmann EP, et al. Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function. Cancer Research. 66: 69-77. PMID 16397218 DOI: 10.1158/0008-5472.Can-05-1550  0.659
2006 Chang BL, Lange EM, Dimitrov L, Valis CJ, Gillanders EM, Lange LA, Wiley KE, Isaacs SD, Wiklund F, Baffoe-Bonnie A, Langefeld CD, Zheng SL, Matikainen MP, Ikonen T, Fredriksson H, ... ... Isaacs WB, et al. Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect. Human Genetics. 118: 716-24. PMID 16328469 DOI: 10.1007/S00439-005-0099-4  0.579
2006 Warlick CA, Pomper MG, Isaacs WB, De Marzo AM, Rodriguez R. 1552: Alpha-Methylacyl-COA Racemase (AMACR)-Based Molecular Imaging of Prostate Cancer Journal of Urology. 175: 501-501. DOI: 10.1016/S0022-5347(18)33756-X  0.544
2006 Gu Y, Li H, Miki J, Kim K, Furusato B, Sesterhenn IA, Chu W, McLeod DG, Ewing CM, Srivastava S, Isaacs WB, Rhim JS. 245: Novel Telomerase-Immortalized Primary Prostate Epithelial Cell Lines Retain Biological Features of Benign and Cancerous Prostate Specimens Journal of Urology. 175: 81-82. DOI: 10.1016/S0022-5347(18)32512-6  0.633
2006 Freedland SJ, Darshan M, Wang A, Luo J, Demarzo AM, Dunn T, Fedor H, Mohan I, Mavropoulos J, Demark-Wahnefried W, Aronson WJ, Isaacs WB. 237: Gene Expression Profiling of Prostate Cancers from Obese Men Identified HMGCS2 as a Novel Biomarker of Aggressive Prostate Cancer and as a Potential Therapeutic Target Journal of Urology. 175: 79-79. DOI: 10.1016/S0022-5347(18)32504-7  0.617
2005 Xu J, Lowey J, Wiklund F, Sun J, Lindmark F, Hsu FC, Dimitrov L, Chang B, Turner AR, Liu W, Adami HO, Suh E, Moore JH, Zheng SL, Isaacs WB, et al. The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 2563-8. PMID 16284379 DOI: 10.1158/1055-9965.Epi-05-0356  0.554
2005 Kouprina N, Pavlicek A, Noskov VN, Solomon G, Otstot J, Isaacs W, Carpten JD, Trent JM, Schleutker J, Barrett JC, Jurka J, Larionov V. Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27. Genome Research. 15: 1477-86. PMID 16251457 DOI: 10.1101/Gr.4212705  0.494
2005 Freedland SJ, Isaacs WB, Platz EA, Terris MK, Aronson WJ, Amling CL, Presti JC, Kane CJ. Prostate size and risk of high-grade, advanced prostate cancer and biochemical progression after radical prostatectomy: a search database study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7546-54. PMID 16234520 DOI: 10.1200/Jco.2005.05.525  0.614
2005 Freedland SJ, Grubb KA, Yiu SK, Nielsen ME, Mangold LA, Isaacs WB, Epstein JI, Partin AW. Obesity and capsular incision at the time of open retropubic radical prostatectomy Journal of Urology. 174: 1798-1801. PMID 16217290 DOI: 10.1097/01.Ju.0000177077.53037.72  0.413
2005 Lindström S, Wiklund F, Jonsson BA, Adami HO, Bälter K, Brookes AJ, Xu J, Zheng SL, Isaacs WB, Adolfsson J, Grönberg H. Comprehensive genetic evaluation of common E-cadherin sequence variants and prostate cancer risk: strong confirmation of functional promoter SNP. Human Genetics. 118: 339-47. PMID 16189707 DOI: 10.1007/S00439-005-0060-6  0.391
2005 Lindmark F, Zheng SL, Wiklund F, Bälter KA, Sun J, Chang B, Hedelin M, Clark J, Johansson JE, Meyers DA, Adami HO, Isaacs W, Grönberg H, Xu J. Interleukin-1 receptor antagonist haplotype associated with prostate cancer risk. British Journal of Cancer. 93: 493-7. PMID 16106254 DOI: 10.1038/Sj.Bjc.6602729  0.507
2005 Freedland SJ, Grubb KA, Yiu SK, Humphreys EB, Nielsen ME, Mangold LA, Isaacs WB, Partin AW. Obesity and risk of biochemical progression following radical prostatectomy at a Tertiary Care Referral Center Journal of Urology. 174: 919-922. PMID 16093988 DOI: 10.1097/01.Ju.0000169459.78982.D7  0.393
2005 Schalken JA, Bergh A, Bono A, Foster C, Gospadarowicz M, Isaacs WB, Rubin M, Schröder F, Tribukait B, Tsukamotot T, Wiklund P. Molecular prostate cancer pathology: current issues and achievements. Scandinavian Journal of Urology and Nephrology. Supplementum. 82-93. PMID 16019760 DOI: 10.1080/03008880510030950  0.591
2005 Xu J, Dimitrov L, Chang BL, Adams TS, Turner AR, Meyers DA, Eeles RA, Easton DF, Foulkes WD, Simard J, Giles GG, Hopper JL, Mahle L, Moller P, Bishop T, ... ... Isaacs WB, et al. A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. American Journal of Human Genetics. 77: 219-29. PMID 15988677 DOI: 10.1086/432377  0.457
2005 Baffoe-Bonnie AB, Smith JR, Stephan DA, Schleutker J, Carpten JD, Kainu T, Gillanders EM, Matikainen M, Teslovich TM, Tammela T, Sood R, Balshem AM, Scarborough SD, Xu J, Isaacs WB, et al. A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region. Human Genetics. 117: 307-16. PMID 15906096 DOI: 10.1007/S00439-005-1306-Z  0.51
2005 Freedland SJ, Isaacs WB, Mangold LA, Yiu SK, Grubb KA, Partin AW, Epstein JI, Walsh PC, Platz EA. Stronger association between obesity and biochemical progression after radical prostatectomy among men treated in the last 10 years. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2883-8. PMID 15837737 DOI: 10.1158/1078-0432.Ccr-04-2257  0.452
2005 Sun J, Wiklund F, Zheng SL, Chang B, Bälter K, Li L, Johansson JE, Li G, Adami HO, Liu W, Tolin A, Turner AR, Meyers DA, Isaacs WB, Xu J, et al. Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk. Journal of the National Cancer Institute. 97: 525-32. PMID 15812078 DOI: 10.1093/Jnci/Dji070  0.536
2005 Zha S, Isaacs WB. A nonclassic CCAAT enhancer element binding protein binding site contributes to alpha-methylacyl-CoA racemase expression in prostate cancer. Molecular Cancer Research : McR. 3: 110-8. PMID 15755877 DOI: 10.1158/1541-7786.Mcr-04-0178  0.736
2005 Chang BL, Isaacs SD, Wiley KE, Gillanders EM, Zheng SL, Meyers DA, Walsh PC, Trent JM, Xu J, Isaacs WB. Genome-wide screen for prostate cancer susceptibility genes in men with clinically significant disease. The Prostate. 64: 356-61. PMID 15754351 DOI: 10.1002/Pros.20249  0.634
2005 Narla G, Difeo A, Reeves HL, Schaid DJ, Hirshfeld J, Hod E, Katz A, Isaacs WB, Hebbring S, Komiya A, McDonnell SK, Wiley KE, Jacobsen SJ, Isaacs SD, Walsh PC, et al. A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk. Cancer Research. 65: 1213-22. PMID 15735005 DOI: 10.1158/0008-5472.Can-04-4249  0.655
2005 Chang BL, Gillanders EM, Isaacs SD, Wiley KE, Adams T, Turner AR, Zheng SL, Meyers DA, Carpten JD, Walsh PC, Trent JM, Xu J, Isaacs WB. Evidence for a general cancer susceptibility locus at 3p24 in families with hereditary prostate cancer. Cancer Letters. 219: 177-82. PMID 15723717 DOI: 10.1016/J.Canlet.2004.10.005  0.576
2005 Kidd LC, Paltoo DN, Wang S, Chen W, Akereyeni F, Isaacs W, Ahaghotu C, Kittles R. Sequence variation within the 5' regulatory regions of the vitamin D binding protein and receptor genes and prostate cancer risk. The Prostate. 64: 272-82. PMID 15717311 DOI: 10.1002/Pros.20204  0.466
2005 Schwarze SR, Luo J, Isaacs WB, Jarrard DF. Modulation of CXCL14 (BRAK) expression in prostate cancer. The Prostate. 64: 67-74. PMID 15651028 DOI: 10.1002/Pros.20215  0.602
2005 Zha S, Ferdinandusse S, Hicks JL, Denis S, Dunn TA, Wanders RJ, Luo J, De Marzo AM, Isaacs WB. Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer. The Prostate. 63: 316-23. PMID 15599942 DOI: 10.1002/Pros.20177  0.762
2005 Palapattu GS, Sutcliffe S, Bastian PJ, Platz EA, De Marzo AM, Isaacs WB, Nelson WG. Prostate carcinogenesis and inflammation: emerging insights. Carcinogenesis. 26: 1170-81. PMID 15498784 DOI: 10.1093/Carcin/Bgh317  0.659
2005 Sun J, Hedelin M, Zheng SL, Adami HO, Bensen J, Augustsson-Bälter K, Chang B, Adolfsson J, Adams T, Turner A, Meyers DA, Isaacs WB, Xu J, Grönberg H. Interleukin-6 sequence variants are not associated with prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 13: 1677-9. PMID 15466986  0.514
2005 Freedland SJ, Isaacs WB. Explaining racial differences in prostate cancer in the United States: sociology or biology? The Prostate. 62: 243-52. PMID 15389726 DOI: 10.1002/Pros.20052  0.577
2005 Freedland SJ, Isaacs WB, Platz EA, Terris MK, Aronson WJ, Amling CL, Presti JC, Kane CJ. 697: Prostate Size is Inversely Associated with Risk of High-Grade, Advanced Prostate Cancer, and Biochemical Progression Following Radical Prostatectomy Journal of Urology. 173: 190-190. DOI: 10.1016/S0022-5347(18)35929-9  0.626
2005 Freedland SJ, Luo J, DeMarzo AM, Dunn T, Fedor H, Darshan M, Mohan I, Isaacs WB. 233: Gene Expression Differences Between Prostate Cancers from Obese and Normal Weight Men Journal of Urology. 173: 64-64. DOI: 10.1016/S0022-5347(18)34498-7  0.532
2005 Ewing CM, Walsh PC, Isaacs WB, Meyers DA, Xu J. 224: Msrl Mutants Implicated in Prostate Cancer Risk Encode Non-Functional Proteins Journal of Urology. 173: 62-62. DOI: 10.1016/S0022-5347(18)34489-6  0.575
2005 Baffoe-Bonnie AB, Smith JR, Stephan DA, Schleutker J, Carpten JD, Kainu T, Gillanders EM, Matikainen M, Teslovich TM, Tammela T, Sood R, Balshem AM, Scarborough SD, Xu J, Isaacs WB, et al. A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region Human Genetics. 118: 307-307. DOI: 10.1007/S00439-005-0050-8  0.609
2004 Nelson WG, De Marzo AM, DeWeese TL, Isaacs WB. The role of inflammation in the pathogenesis of prostate cancer. The Journal of Urology. 172: S6-11; discussion S1. PMID 15535435 DOI: 10.1097/01.Ju.0000142058.99614.Ff  0.648
2004 Zha S, Yegnasubramanian V, Nelson WG, Isaacs WB, De Marzo AM. Cyclooxygenases in cancer: progress and perspective. Cancer Letters. 215: 1-20. PMID 15374627 DOI: 10.1016/J.Canlet.2004.06.014  0.694
2004 Rogers CG, Yan G, Zha S, Gonzalgo ML, Isaacs WB, Luo J, De Marzo AM, Nelson WG, Pavlovich CP. Prostate cancer detection on urinalysis for alpha methylacyl coenzyme a racemase protein. The Journal of Urology. 172: 1501-3. PMID 15371879 DOI: 10.1097/01.Ju.0000137659.53129.14  0.785
2004 Faith DA, Isaacs WB, Morgan JD, Fedor HL, Hicks JL, Mangold LA, Walsh PC, Partin AW, Platz EA, Luo J, De Marzo AM. Trefoil factor 3 overexpression in prostatic carcinoma: Prognostic importance using tissue microarrays Prostate. 61: 215-227. PMID 15368473 DOI: 10.1002/Pros.20095  0.593
2004 Lindmark F, Zheng SL, Wiklund F, Bensen J, Bälter KA, Chang B, Hedelin M, Clark J, Stattin P, Meyers DA, Adami HO, Isaacs W, Grönberg H, Xu J. H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer. Journal of the National Cancer Institute. 96: 1248-54. PMID 15316060 DOI: 10.1093/Jnci/Djh227  0.612
2004 Gillanders EM, Xu J, Chang BL, Lange EM, Wiklund F, Bailey-Wilson JE, Baffoe-Bonnie A, Jones M, Gildea D, Riedesel E, Albertus J, Isaacs SD, Wiley KE, Mohai CE, Matikainen MP, ... ... Isaacs WB, et al. Combined genome-wide scan for prostate cancer susceptibility genes. Journal of the National Cancer Institute. 96: 1240-7. PMID 15316059 DOI: 10.1093/Jnci/Djh228  0.64
2004 Hawkins GA, Chang BL, Zheng SL, Isaacs SD, Wiley KE, Bleecker ER, Walsh PC, Meyers DA, Xu J, Isaacs WB. Mutational analysis of PINX1 in hereditary prostate cancer. The Prostate. 60: 298-302. PMID 15264240 DOI: 10.1002/Pros.20075  0.606
2004 Xu J, Langefeld CD, Zheng SL, Gillanders EM, Chang BL, Isaacs SD, Williams AH, Wiley KE, Dimitrov L, Meyers DA, Walsh PC, Trent JM, Isaacs WB. Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage. Human Genetics. 115: 255-62. PMID 15185141 DOI: 10.1007/S00439-004-1144-4  0.547
2004 Carter HB, Isaacs WB. Improved biomarkers for prostate cancer: a definite need. Journal of the National Cancer Institute. 96: 813-5. PMID 15173257 DOI: 10.1093/Jnci/Djh174  0.621
2004 Zheng SL, Augustsson-Bälter K, Chang B, Hedelin M, Li L, Adami HO, Bensen J, Li G, Johnasson JE, Turner AR, Adams TS, Meyers DA, Isaacs WB, Xu J, Grönberg H. Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study. Cancer Research. 64: 2918-22. PMID 15087412 DOI: 10.1158/0008-5472.Can-03-3280  0.625
2004 Chesire DR, Dunn TA, Ewing CM, Luo J, Isaacs WB. Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells. Cancer Research. 64: 2523-33. PMID 15059908 DOI: 10.1158/0008-5472.Can-03-3309  0.802
2004 Chang BL, Zheng SL, Isaacs SD, Wiley KE, Turner A, Li G, Walsh PC, Meyers DA, Isaacs WB, Xu J. A polymorphism in the CDKN1B gene is associated with increased risk of hereditary prostate cancer. Cancer Research. 64: 1997-9. PMID 15026335 DOI: 10.1158/0008-5472.Can-03-2340  0.633
2004 Yegnasubramanian S, Kowalski J, Gonzalgo ML, Zahurak M, Piantadosi S, Walsh PC, Bova GS, De Marzo AM, Isaacs WB, Nelson WG. Hypermethylation of CpG islands in primary and metastatic human prostate cancer. Cancer Research. 64: 1975-86. PMID 15026333 DOI: 10.1158/0008-5472.Can-03-3972  0.653
2004 Kibel AS, Huagen J, Guo C, Isaacs WB, Yan Y, Pienta KJ, Goodfellow PJ. Expression mapping at 12p12-13 in advanced prostate carcinoma. International Journal of Cancer. 109: 668-72. PMID 14999772 DOI: 10.1002/Ijc.20060  0.594
2004 Friedrichsen DM, Stanford JL, Isaacs SD, Janer M, Chang BL, Deutsch K, Gillanders E, Kolb S, Wiley KE, Badzioch MD, Zheng SL, Walsh PC, Jarvik GP, Hood L, Trent JM, ... Isaacs WB, et al. Identification of a prostate cancer susceptibility locus on chromosome 7q11-21 in Jewish families. Proceedings of the National Academy of Sciences of the United States of America. 101: 1939-44. PMID 14769943 DOI: 10.1073/Pnas.0308336100  0.591
2004 De Marzo AM, DeWeese TL, Platz EA, Meeker AK, Nakayama M, Epstein JI, Isaacs WB, Nelson WG. Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment. Journal of Cellular Biochemistry. 91: 459-77. PMID 14755677 DOI: 10.1002/Jcb.10747  0.756
2004 Panguluri RC, Long LO, Chen W, Wang S, Coulibaly A, Ukoli F, Jackson A, Weinrich S, Ahaghotu C, Isaacs W, Kittles RA. COX-2 gene promoter haplotypes and prostate cancer risk. Carcinogenesis. 25: 961-6. PMID 14754878 DOI: 10.1093/Carcin/Bgh100  0.561
2004 Brown WM, Lange EM, Chen H, Zheng SL, Chang B, Wiley KE, Isaacs SD, Walsh PC, Isaacs WB, Xu J, Cooney KA. Hereditary prostate cancer in African American families: linkage analysis using markers that map to five candidate susceptibility loci. British Journal of Cancer. 90: 510-4. PMID 14735201 DOI: 10.1038/Sj.Bjc.6601417  0.63
2004 Isaacs JT, Isaacs WB. Androgen receptor outwits prostate cancer drugs. Nature Medicine. 10: 26-7. PMID 14702629 DOI: 10.1038/Nm0104-26  0.581
2004 Gonzalgo ML, Isaacs WB. Molecular pathways to prostate cancer. The Journal of Urology. 170: 2444-52. PMID 14634448 DOI: 10.1097/01.Ju.0000085381.20139.B6  0.625
2004 Schwarze SR, Isaacs WB, Oberley TO, Jarrard DF. 587: Cxcl14 (BRAK) Expression is Elevated in Prostate Cancer and May Promote Tumor Progression Through Inflammation and Endothelial Cell Recruitment Journal of Urology. 171: 156-156. DOI: 10.1016/S0022-5347(18)37849-2  0.576
2004 Parsons JK, Mitchell RJ, Vessella RL, Sawyers CL, Isaacs WB, Faith DA, Bova GS, De Marzo AM. 415: Mutational Analysis of the P63 Gene in Prostate Cancer Cells Journal of Urology. 171: 110-110. DOI: 10.1016/S0022-5347(18)37677-8  0.581
2004 Long LO, Ahaghotu CA, Jackson AG, Freeman V, Ewing C, Xu J, Isaacs WB, Kittles RA. 411: Macrophage Scavenger Receptor 1 Haplotype Variation and Prostate Cancer Risk in Populations of African Descent Journal of Urology. 171: 109-109. DOI: 10.1016/S0022-5347(18)37673-0  0.557
2003 Luo J, Isaacs WB, Trent JM, Duggan DJ. Looking Beyond Morphology: Cancer Gene Expression Profiling Using DNA Microarrays Cancer Investigation. 21: 937-949. PMID 14735697 DOI: 10.1081/Cnv-120025096  0.503
2003 Chesire DR, Isaacs WB. Beta-catenin signaling in prostate cancer: an early perspective. Endocrine-Related Cancer. 10: 537-60. PMID 14713266 DOI: 10.1677/Erc.0.0100537  0.843
2003 Zha S, Ferdinandusse S, Denis S, Wanders RJ, Ewing CM, Luo J, De Marzo AM, Isaacs WB. Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer. Cancer Research. 63: 7365-76. PMID 14612535  0.72
2003 De Marzo AM, Meeker AK, Zha S, Luo J, Nakayama M, Platz EA, Isaacs WB, Nelson WG. Human prostate cancer precursors and pathobiology. Urology. 62: 55-62. PMID 14607218 DOI: 10.1016/J.Urology.2003.09.053  0.851
2003 Xu J, Gillanders EM, Isaacs SD, Chang BL, Wiley KE, Zheng SL, Jones M, Gildea D, Riedesel E, Albertus J, Freas-Lutz D, Markey C, Meyers DA, Walsh PC, Trent JM, ... Isaacs WB, et al. Genome-wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families. The Prostate. 57: 320-5. PMID 14601028 DOI: 10.1002/Pros.10306  0.618
2003 Xiang Y, Wang Z, Murakami J, Plummer S, Klein EA, Carpten JD, Trent JM, Isaacs WB, Casey G, Silverman RH. Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates. Cancer Research. 63: 6795-801. PMID 14583476  0.452
2003 Chang BL, Zheng SL, Isaacs SD, Turner A, Hawkins GA, Wiley KE, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB, Xu J. Polymorphisms in the CYP1B1 gene are associated with increased risk of prostate cancer. British Journal of Cancer. 89: 1524-9. PMID 14562027 DOI: 10.1038/Sj.Bjc.6601288  0.378
2003 Luo J, Dunn TA, Ewing CM, Walsh PC, Isaacs WB. Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: implications for finasteride therapy of prostate carcinoma. The Prostate. 57: 134-9. PMID 12949937 DOI: 10.1002/Pros.10284  0.623
2003 Magi-Galluzzi C, Luo J, Isaacs WB, Hicks JL, De Marzo AM, Epstein JI. α-methylacyl-CoA racemase: A variably sensitive immunohistochemical marker for the diagnosis of small prostate cancer foci on needle biopsy American Journal of Surgical Pathology. 27: 1128-1133. PMID 12883245 DOI: 10.1097/00000478-200308000-00010  0.595
2003 Nelson WG, De Marzo AM, Isaacs WB. Prostate cancer. The New England Journal of Medicine. 349: 366-81. PMID 12878745 DOI: 10.1056/NEJMra021562  0.58
2003 Zheng SL, Mychaleckyj JC, Hawkins GA, Isaacs SD, Wiley KE, Turner A, Chang BL, von Kap-Herr C, Carpten JD, Pettenati M, Bleecker ER, Walsh PC, Trent JM, Meyers DA, Isaacs WB, et al. Evaluation of DLC1 as a prostate cancer susceptibility gene: mutation screen and association study. Mutation Research. 528: 45-53. PMID 12873722 DOI: 10.1016/S0027-5107(03)00081-2  0.631
2003 Chang BL, Zheng SL, Isaacs SD, Turner A, Hawkins GA, Wiley KE, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB, Xu J. Polymorphisms in the CYP1A1 gene are associated with prostate cancer risk. International Journal of Cancer. 106: 375-8. PMID 12845676 DOI: 10.1002/Ijc.11249  0.309
2003 Kibel AS, Faith DA, Bova GS, Isaacs WB. Xq27-28 deletions in prostate carcinoma. Genes, Chromosomes & Cancer. 37: 381-8. PMID 12800149 DOI: 10.1002/Gcc.10230  0.645
2003 Chang BL, Zheng SL, Isaacs SD, Turner AR, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB, Xu J. Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer. The Prostate. 56: 37-44. PMID 12746845 DOI: 10.1002/Pros.10225  0.63
2003 Pearson JD, Lei HH, Beaty TH, Wiley KE, Isaacs SD, Isaacs WB, Stoner E, Walsh PC. Familial aggregation of bothersome benign prostatic hyperplasia symptoms. Urology. 61: 781-5. PMID 12670565 DOI: 10.1016/S0090-4295(02)02509-8  0.519
2003 DeMarzo AM, Nelson WG, Isaacs WB, Epstein JI. Pathological and molecular aspects of prostate cancer. Lancet (London, England). 361: 955-64. PMID 12648986 DOI: 10.1016/S0140-6736(03)12779-1  0.631
2003 Xu J, Zheng SL, Komiya A, Mychaleckyj JC, Isaacs SD, Chang B, Turner AR, Ewing CM, Wiley KE, Hawkins GA, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB. Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. American Journal of Human Genetics. 72: 208-12. PMID 12471593 DOI: 10.1086/345802  0.653
2003 Isaacs W, De Marzo A, Nelson WG. Focus on prostate cancer. Cancer Cell. 2: 113-6. PMID 12204531 DOI: 10.1016/S1535-6108(02)00103-4  0.619
2002 Chesire DR, Isaacs WB. Ligand-dependent inhibition of beta-catenin/TCF signaling by androgen receptor. Oncogene. 21: 8453-69. PMID 12466965 DOI: 10.1038/Sj.Onc.1206049  0.803
2002 Zheng SL, Chang BL, Faith DA, Johnson JR, Isaacs SD, Hawkins GA, Turner A, Wiley KE, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB, Xu J. Sequence variants of alpha-methylacyl-CoA racemase are associated with prostate cancer risk. Cancer Research. 62: 6485-8. PMID 12438241  0.473
2002 Hawkins GA, Cramer SD, Zheng SL, Isaacs SD, Wiley KE, Chang BL, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB, Xu J. Sequence variants in the human 25-hydroxyvitamin D3 1-α-hydroxylase (CYP27BI) gene are not associated with prostate cancer risk Prostate. 53: 175-178. PMID 12386916 DOI: 10.1002/Pros.10144  0.569
2002 Hawkins GA, Mychaleckyj JC, Zheng SL, Faith DA, Kelly B, Isaacs SD, Wiley KE, Chang BL, Ewing CM, Bujnovszky P, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB, Xu J. Germline sequence variants of the LZTS1 gene are associated with prostate cancer risk Cancer Genetics and Cytogenetics. 137: 1-7. PMID 12377406 DOI: 10.1016/S0165-4608(02)00549-6  0.63
2002 Xu J, Zheng SL, Komiya A, Mychaleckyj JC, Isaacs SD, Hu JJ, Sterling D, Lange EM, Hawkins GA, Turner A, Ewing CM, Faith DA, Johnson JR, Suzuki H, Bujnovszky P, ... ... Isaacs WB, et al. Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nature Genetics. 32: 321-5. PMID 12244320 DOI: 10.1038/Ng994  0.632
2002 Kibel AS, Faith DA, Bova GS, Isaacs WB. Mutational analysis of ETV6 in prostate carcinoma. The Prostate. 52: 305-10. PMID 12210491 DOI: 10.1002/Pros.10112  0.606
2002 Kittles RA, Chen W, Panguluri RK, Ahaghotu C, Jackson A, Adebamowo CA, Griffin R, Williams T, Ukoli F, Adams-Campbell L, Kwagyan J, Isaacs W, Freeman V, Dunston GM. CYP3A4-V and prostate cancer in African Americans: causal or confounding association because of population stratification? Human Genetics. 110: 553-60. PMID 12107441 DOI: 10.1007/S00439-002-0731-5  0.488
2002 Luo J, Dunn T, Ewing C, Sauvageot J, Chen Y, Trent J, Isaacs W. Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis. The Prostate. 51: 189-200. PMID 11967953 DOI: 10.1002/Pros.10087  0.556
2002 Chesire DR, Ewing CM, Gage WR, Isaacs WB. In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis. Oncogene. 21: 2679-94. PMID 11965541 DOI: 10.1038/Sj.Onc.1205352  0.826
2002 Xu J, Zheng SL, Turner A, Isaacs SD, Wiley KE, Hawkins GA, Chang BL, Bleecker ER, Walsh PC, Meyers DA, Isaacs WB. Associations between hOGG1 sequence variants and prostate cancer susceptibility Cancer Research. 62: 2253-2257. PMID 11956079  0.465
2002 Luo J, Zha S, Gage WR, Dunn TA, Hicks JL, Bennett CJ, Ewing CM, Platz EA, Ferdinandusse S, Wanders RJ, Trent JM, Isaacs WB, De Marzo AM. Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer. Cancer Research. 62: 2220-6. PMID 11956072  0.807
2002 Ho GY, Knapp M, Freije D, Nelson WG, Smith JR, Carpten JD, Bailey-Wilson JE, Beaty TH, Petersen G, Xu J, Kamensky V, Walsh PC, Isaacs WB. Transmission/disequilibrium tests of androgen receptor and glutathione S-transferase pi variants in prostate cancer families. International Journal of Cancer. Journal International Du Cancer. 98: 938-42. PMID 11948476 DOI: 10.1002/Ijc.10290  0.543
2002 Chang BL, Zheng SL, Hawkins GA, Isaacs SD, Wiley KE, Turner A, Carpten JD, Bleecker ER, Walsh PC, Trent JM, Meyers DA, Isaacs WB, Xu J. Polymorphic GGC repeats in the androgen receptor gene are associated with hereditary and sporadic prostate cancer risk Human Genetics. 110: 122-129. PMID 11935317 DOI: 10.1007/S00439-001-0662-6  0.635
2002 Chang BL, Zheng SL, Hawkins GA, Isaacs SD, Wiley KE, Turner A, Carpten JD, Bleecker ER, Walsh PC, Trent JM, Meyers DA, Isaacs WB, Xu J. Joint effect of HSD3B1 and HSD3B2 genes is associated with hereditary and sporadic prostate cancer susceptibility Cancer Research. 62: 1784-1789. PMID 11912155  0.591
2002 Takaha N, Hawkins AL, Griffin CA, Isaacs WB, Coffey DS. High mobility group protein I(Y): a candidate architectural protein for chromosomal rearrangements in prostate cancer cells. Cancer Research. 62: 647-51. PMID 11830513  0.578
2002 Stephan DA, Howell GR, Teslovich TM, Coffey AJ, Smith L, Bailey-Wilson JE, Malechek L, Gildea D, Smith JR, Gillanders EM, Schleutker J, Hu P, Steingruber HE, Dhami P, Robbins CM, ... ... Isaacs W, et al. Physical and transcript map of the hereditary prostate cancer region at xq27. Genomics. 79: 41-50. PMID 11827456 DOI: 10.1006/Geno.2001.6681  0.371
2002 Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing C, Gillanders E, Hu P, Bujnovszky P, Makalowska I, Baffoe-Bonnie A, Faith D, ... ... Isaacs W, et al. Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nature Genetics. 30: 181-4. PMID 11799394 DOI: 10.1038/Ng823  0.522
2002 Isaacs W, Kainu T. Oncogenes and tumor suppressor genes in prostate cancer. Epidemiologic Reviews. 23: 36-41. PMID 11588853 DOI: 10.1093/Oxfordjournals.Epirev.A000794  0.54
2001 Zha S, Gage WR, Sauvageot J, Saria EA, Putzi MJ, Ewing CM, Faith DA, Nelson WG, De Marzo AM, Isaacs WB. Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma. Cancer Research. 61: 8617-23. PMID 11751373  0.779
2001 Lin X, Tascilar M, Lee WH, Vles WJ, Lee BH, Veeraswamy R, Asgari K, Freije D, Van Rees B, Gage WR, Bova GS, Isaacs WB, Brooks JD, Deweese TL, De Marzo AM, et al. GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells American Journal of Pathology. 159: 1815-1826. PMID 11696442 DOI: 10.1016/S0002-9440(10)63028-3  0.483
2001 Chang BL, Zheng SL, Isaacs SD, Wiley KE, Carpten JD, Hawkins GA, Bleecker ER, Walsh PC, Trent JM, Meyers DA, Isaacs WB, Xu J. Linkage and association of CYP17 gene in hereditary and sporadic prostate cancer International Journal of Cancer. 95: 354-359. PMID 11668516 DOI: 10.1002/1097-0215(20011120)95:6<354::Aid-Ijc1062>3.0.Co;2-3  0.645
2001 Hsing AW, Chang L, Nomura AM, Isaacs WB, Armenian HK. A glimpse into the future Epidemiologic Reviews. 23: 2. PMID 11588849 DOI: 10.1093/Oxfordjournals.Epirev.A000790  0.58
2001 Kibel AS, Christopher M, Faith DA, Bova GS, Goodfellow PJ, Isaacs WB. Methylation and mutational analysis of p27(kip1) in prostate carcinoma. The Prostate. 48: 248-53. PMID 11536304 DOI: 10.1002/Pros.1104  0.559
2001 Xu J, Zheng SL, Hawkins GA, Faith DA, Kelly B, Isaacs SD, Wiley KE, Chang BL, Ewing CM, Bujnovszky P, Carpten JD, Bleecker ER, Walsh PC, Trent JM, Meyers DA, ... Isaacs WB, et al. Linkage and association studies of prostate cancer susceptibility: Evidence for linkage at 8p22-23 American Journal of Human Genetics. 69: 341-350. PMID 11443539 DOI: 10.1086/321967  0.6
2001 Zheng SL, Xu J, Isaacs SD, Wiley K, Chang BI, Bleecker ER, Walsh PC, Trent JM, Meyers DA, Isaacs WB. Evidence for a prostate cancer linkage to chromosome 20 in 159 hereditary prostate cancer families Human Genetics. 108: 430-435. PMID 11409871 DOI: 10.1007/S004390100513  0.579
2001 Xu J, Zheng SL, Chang BL, Smith JR, Carpten JD, Stine OC, Isaacs SD, Wiley KE, Henning L, Ewing C, Bujnovszky P, Bleeker ER, Walsh PC, Trent JM, Meyers DA, ... Isaacs WB, et al. Linkage of prostate cancer susceptibility loci to chromosome 1 Human Genetics. 108: 335-345. PMID 11379880 DOI: 10.1007/S004390100488  0.439
2001 Xu J, Zheng SL, Carpten JD, Nupponen NN, Robbins CM, Mestre J, Moses TY, Faith DA, Kelly BD, Isaacs SD, Wiley KE, Ewing CM, Bujnovszky P, Chang B, Bailey-Wilson J, ... ... Isaacs WB, et al. Evaluation of linkage and association of HPC2/ELAC2 in patients with familial or sporadic prostate cancer. American Journal of Human Genetics. 68: 901-11. PMID 11254448 DOI: 10.1086/319513  0.637
2001 Duggan DJ, Luo J, Sauvageot J, Bittner M, Chen Y, Trent J, Isaacs WB. Molecular profiling of prostate cancer progression Nature Genetics. 27: 51-52. DOI: 10.1038/87064  0.608
2000 Chesire DR, Ewing CM, Sauvageot J, Bova GS, Isaacs WB. Detection and analysis of beta-catenin mutations in prostate cancer. The Prostate. 45: 323-34. PMID 11102958 DOI: 10.1002/1097-0045(20001201)45:4<323::Aid-Pros7>3.0.Co;2-W  0.826
2000 Kibel AS, Isaacs WB. G(1)/S cell cycle proteins as markers of aggressive prostate carcinoma. Urology. 55: 316-22. PMID 10699600 DOI: 10.1016/S0090-4295(99)00478-1  0.488
2000 KIBEL AS, FAITH DA, BOVA GS, ISAACS WB. LOSS OF HETEROZYGOSITY AT 12P12–13 IN PRIMARY AND METASTATIC PROSTATE ADENOCARCINOMA Journal of Urology. 164: 192-196. DOI: 10.1016/S0022-5347(05)67493-9  0.56
1999 Kibel AS, Freije D, Isaacs WB, Bova GS. Deletion mapping at 12p12-13 in metastatic prostate cancer. Genes, Chromosomes & Cancer. 25: 270-6. PMID 10379873 DOI: 10.1002/(Sici)1098-2264(199907)25:3<270::Aid-Gcc9>3.0.Co;2-Z  0.503
1999 Grönberg H, Smith J, Emanuelsson M, Jonsson BA, Bergh A, Carpten J, Isaacs W, Xu J, Meyers D, Trent J, Damber JE. In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancer. American Journal of Human Genetics. 65: 134-40. PMID 10364525 DOI: 10.1086/302447  0.561
1999 Wilkens EP, Freije D, Xu J, Nusskern DR, Suzuki H, Isaacs SD, Wiley K, Bujnovszky P, Meyers DA, Walsh PC, Isaacs WB. No evidence for a role of BRCA1 or BRCA2 mutations in Ashkenazi Jewish families with hereditary prostate cancer Prostate. 39: 280-284. PMID 10344217 DOI: 10.1002/(Sici)1097-0045(19990601)39:4<280::Aid-Pros8>3.0.Co;2-F  0.517
1999 Lei H, Beaty TH, Wiley KE, Isaacs SD, Isaacs WB, Walsh PC, Pearson JD. Segregation Analysis Of Symptomatic Benign Prostatic Hyperplasia: North American Finasteride Trial The Journal of Urology. 290. DOI: 10.1097/00005392-199904020-00162  0.55
1999 Kibel AS, Faith D, Bova SG, Isaacs W. LOSS OF HETEROZYGOSITY AT THE p27/KIP1 LOCUS IN PRIMARY AND METASTATIC PROSTATE CARCINOMA The Journal of Urology. 235. DOI: 10.1097/00005392-199904010-00943  0.513
1999 Kinoshita H, Shi Y, Sandefur C, Chang C, Jarrard DF, Herman JG, Bova GS, Isaacs WB. METHYLATION OF THE ANDROGEN RECEPTOR PROMOTER CpG ISLAND IS ASSOCIATED WITH LOSS OF ANDROGEN RECEPTOR (AR) EXPRESSION IN PROSTATE CANCER CELLS The Journal of Urology. 63. DOI: 10.1097/00005392-199904010-00253  0.544
1999 Matikainen MP, Schleutker J, Koivisto PA, Tammela T, Xu J, Isaacs WB, Smith JR, Carpten JD, Stephan DA, Bailey-Wilson JE, Trent JM, Kallioniemi O. Genetic Epidemiology Of Hereditary Prostate Cancer In Finland: Discovery Of Novel Susceptibility Loci The Journal of Urology. 54. DOI: 10.1097/00005392-199904010-00220  0.602
1999 Kibel AS, DeMarzo A, Freije D, Isaacs WB, Bova GS. DELETION MAPPING AT 12p12-13 IN METASTATIC PROSTATE CARCINOMA The Journal of Urology. 54. DOI: 10.1097/00005392-199904010-00219  0.499
1999 Bova G, Partin A, Isaacs S, Carter B, Beaty T, Isaacs W, Walsh P. RE: BIOLOGICAL AGGRESSIVENESS OF HEREDITARY PROSTATE CANCER Journal of Urology. 161: 1586-1586. DOI: 10.1016/S0022-5347(05)68985-9  0.578
1999 Xu J, Meyers D, Freije D, Isaacs S, Wiley K, Nusskern D, Ewing C, Wilkens E, Bujnovszky P, Bova G, Walsh P, Isaacs W, Schleutker J, Matikainen M, Tammela T, et al. Evidence for a Prostate Cancer Susceptibility Locus on the X Chromosome Journal of Urology. 161: 1386-1386. DOI: 10.1016/S0022-5347(01)61689-6  0.477
1998 Xu J, Meyers D, Freije D, Isaacs S, Wiley K, Nusskern D, Ewing C, Wilkens E, Bujnovszky P, Bova GS, Walsh P, Isaacs W, Schleutker J, Matikainen M, Tammela T, et al. Evidence for a prostate cancer susceptibility locus on the X chromosome. Nature Genetics. 20: 175-9. PMID 9771711 DOI: 10.1016/S0022-5347(01)61689-6  0.612
1998 Bova GS, Partin AW, Isaacs SD, Carter BS, Beaty TL, Isaacs WB, Walsh PC. Biological aggressiveness of hereditary prostate cancer: Long-term evaluation following radical prostatectomy Journal of Urology. 160: 660-663. PMID 9720516 DOI: 10.1016/S0022-5347(01)62748-4  0.624
1998 Chin RK, Hawkins AL, Isaacs WB, Griffin CA. E1A transformed normal human prostate epithelial cells contain a 16q deletion Cancer Genetics and Cytogenetics. 103: 155-163. PMID 9614916 DOI: 10.1016/S0165-4608(97)00407-X  0.55
1998 Whang YE, Wu X, Suzuki H, Reiter RE, Tran C, Vessella RL, Said JW, Isaacs WB, Sawyers CL. Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. Proceedings of the National Academy of Sciences of the United States of America. 95: 5246-50. PMID 9560261 DOI: 10.1073/Pnas.95.9.5246  0.557
1998 Gronberg H, Isaacs S, Smith J, Carpten J, Bova G, Freije D, Xu J, Meyers D, Collins F, Trent J, Walsh P, Isaacs W. Characteristics of Prostate Cancer in Families Potentially Linked to the Hereditary Prostate Cancer 1 (HPC1) Locus Journal of Urology. 159: 1399-1400. DOI: 10.1016/S0022-5347(01)63631-0  0.604
1998 Gronberg H, Xu J, Smith J, Carpten J, Isaacs S, Freije D, Bova G, Walsh P, Collins F, Trent J, Meyers D, Isaacs W. Early Age at Diagnosis in Families Providing Evidence of Linkage to the Hereditary Prostate Cancer Locus (HPC1) on Chromosome 1 Journal of Urology. 160: 265-266. DOI: 10.1016/S0022-5347(01)63105-7  0.526
1998 KIBEL AS, ISAACS SD, ISAACS WB, BOVA GS. VITAMIN D RECEPTOR POLYMORPHISMS AND LETHAL PROSTATE CANCER Journal of Urology. 160: 1405-1409. DOI: 10.1016/S0022-5347(01)62550-3  0.548
1997 Grönberg H, Isaacs SD, Smith JR, Carpten JD, Bova GS, Freije D, Xu J, Meyers DA, Collins FS, Trent JM, Walsh PC, Isaacs WB. Characteristics of prostate cancer in families potentially linked to the hereditary prostate cancer 1 (HPC1) locus. Jama. 278: 1251-5. PMID 9333266 DOI: 10.1001/Jama.1997.03550150055035  0.653
1997 Umbas R, Isaacs WB, Bringuier PP, Xue Y, Debruyne FM, Schalken JA. Relation between aberrant alpha-catenin expression and loss of E-cadherin function in prostate cancer. International Journal of Cancer. 74: 374-7. PMID 9291424 DOI: 10.1002/(Sici)1097-0215(19970822)74:4<374::Aid-Ijc2>3.0.Co;2-S  0.416
1997 Jarrard DF, Bova GS, Ewing CM, Pin SS, Nguyen SH, Baylin SB, Cairns P, Sidransky D, Herman JG, Isaacs WB. Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer. Genes, Chromosomes & Cancer. 19: 90-6. PMID 9171999 DOI: 10.1002/(Sici)1098-2264(199706)19:2<90::Aid-Gcc4>3.0.Co;2-V  0.556
1997 Dong JT, Isaacs WB, Barrett JC, Isaacs JT. Genomic organization of the human KAI1 metastasis-suppressor gene Genomics. 41: 25-32. PMID 9126478 DOI: 10.1006/Geno.1997.4618  0.365
1997 Dong JT, Isaacs WB, Isaacs JT. Molecular advances in prostate cancer Current Opinion in Oncology. 9: 101-107. PMID 9090501 DOI: 10.1097/00001622-199701000-00016  0.64
1997 Paul R, Ewing CM, Jarrard DF, Isaacs WB. The cadherin cell-cell adhesion pathway in prostate cancer progression. British Journal of Urology. 37-43. PMID 9088271 DOI: 10.1111/J.1464-410X.1997.Tb00799.X  0.509
1997 Bookstein R, Bova GS, MacGrogan D, Levy A, Isaacs WB. Tumour-suppressor genes in prostatic oncogenesis: a positional approach. British Journal of Urology. 28-36. PMID 9088270 DOI: 10.1111/J.1464-410X.1997.Tb00798.X  0.489
1997 Bova GS, Isaacs WB. Review of allelic loss and gain in prostate cancer. World Journal of Urology. 14: 338-46. PMID 8912474 DOI: 10.1007/Bf00184607  0.417
1997 Trent J, Smith J, Freije D, Carpten J, Gronberg H, Xu J, Isaacs S, Brownstein M, Bova G, Guo H, Bujnovszky P, Nusskern D, Damber J, Bergh A, Emanuelsson M, ... ... Isaacs W, et al. Identification of a major susceptibility locus for human prostate cancer Cancer Genetics and Cytogenetics. 98: 146. DOI: 10.1016/S0165-4608(97)90228-4  0.632
1996 Smith JR, Freije D, Carpten JD, Grönberg H, Xu J, Isaacs SD, Brownstein MJ, Bova GS, Guo H, Bujnovszky P, Nusskern DR, Damber JE, Bergh A, Emanuelsson M, Kallioniemi OP, ... ... Isaacs WB, et al. Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science (New York, N.Y.). 274: 1371-4. PMID 8910276 DOI: 10.1126/Science.274.5291.1371  0.583
1996 Bova GS, MacGrogan D, Levy A, Pin SS, Bookstein R, Isaacs WB. Physical mapping of chromosome 8p22 markers and their homozygous deletion in a metastatic prostate cancer. Genomics. 35: 46-54. PMID 8661103 DOI: 10.1006/Geno.1996.0321  0.431
1996 Morton RA, Watkins JJ, Bova SG, Wales MM, Baylin SB, Isaacs WB. Hypermethylation of Chromosome 17P Locust D17S5 in Human Prostate Tissue Journal of Urology. 156: 512-516. DOI: 10.1016/S0022-5347(01)65916-0  0.384
1996 Jarrard DF, Bova GS, Isaacs WB. DNA methylation, molecular genetic, and linkage studies in prostate cancer The Prostate. 29: 36-44. DOI: 10.1002/(Sici)1097-0045(1996)6+<36::Aid-Pros8>3.0.Co;2-I  0.597
1995 Morton RA, Ewing CM, Watkins JJ, Isaacs WB. The E-cadherin cell-cell adhesion pathway in urologic malignancies. World Journal of Urology. 13: 364-8. PMID 9116756 DOI: 10.1007/Bf00191218  0.537
1995 Brooks JD, Bova GS, Isaacs WB. Allelic loss of the retinoblastoma gene in primary human prostatic adenocarcinomas. The Prostate. 26: 35-9. PMID 7845865 DOI: 10.1002/Pros.2990260108  0.551
1995 Isaacs WB, Bova GS, Morton RA, Bussemakers MJ, Brooks JD, Ewing CM. Genetic alterations in prostate cancer. Cold Spring Harbor Symposia On Quantitative Biology. 59: 653-9. PMID 7587126 DOI: 10.1101/Sqb.1994.059.01.075  0.628
1995 Cairns P, Polascik TJ, Eby Y, Tokino K, Califano J, Merlo A, Mao L, Herath J, Jenkins R, Westra W, Rutter JL, Buckler A, Gabrielson E, Tockman M, Cho KR, ... ... Isaacs W, et al. Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. Nature Genetics. 11: 210-212. PMID 7550353 DOI: 10.1038/Ng1095-210  0.36
1995 Bell FW, Klausner JS, Hayden DW, Lund EM, Liebenstein BB, Feeney DA, Johnston SD, Shivers JL, Ewing CM, Isaacs WB. Evaluation of serum and seminal plasma markers in the diagnosis of canine prostatic disorders. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 9: 149-53. PMID 7545754 DOI: 10.1111/J.1939-1676.1995.Tb03288.X  0.597
1995 Isaacs WB. Mini review:Molecular biology of prostate cancer Radiation Oncology Investigations. 3: 353-357. DOI: 10.1002/roi.2970030620  0.528
1995 Isaacs WB, Bova GS, Morton RA, Bussemakers MJG, Brooks JD, Ewing CM. Molecular genetics and chromosomal alterations in prostate cancer Cancer. 75: 2004-2012. DOI: 10.1002/1097-0142(19950401)75:7+<2004::Aid-Cncr2820751642>3.0.Co;2-Q  0.57
1994 Schoenberg MP, Hakimi JM, Wang S, Bova GS, Epstein JI, Fischbeck KH, Isaacs WB, Walsh PC, Barrack ER. Microsatellite mutation (CAG24-->18) in the androgen receptor gene in human prostate cancer. Biochemical and Biophysical Research Communications. 198: 74-80. PMID 8292051 DOI: 10.1006/Bbrc.1994.1011  0.494
1994 Moody DB, Robinson JC, Ewing CM, Lazenby AJ, Isaacs WB. Interleukin-2 transfected prostate cancer cells generate a local antitumor effect in vivo. The Prostate. 24: 244-51. PMID 8170837 DOI: 10.1002/Pros.2990240505  0.41
1994 Lee WH, Morton RA, Epstein JI, Brooks JD, Campbell PA, Bova GS, Hsieh WS, Isaacs WB, Nelson WG. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 91: 11733-7. PMID 7972132 DOI: 10.1073/Pnas.91.24.11733  0.609
1994 Rinker-Schaeffer CW, Partin AW, Isaacs WB, Coffey DS, Isaacs JT. Molecular and cellular changes associated with the acquisition of metastatic ability by prostatic cancer cells Prostate. 25: 249-265. PMID 7971516 DOI: 10.1002/Pros.2990250505  0.763
1993 Rinker-Schaeffer CW, Isaacs WB, Isaacs JT. Molecular and cellular markers for metastatic prostate cancer. Cancer Metastasis Reviews. 12: 3-10. PMID 8448825 DOI: 10.1007/Bf00689785  0.632
1993 Brooks JD, Bova GS, Marshall FF, Isaacs WB. Tumor suppressor gene allelic loss in human renal cancers. The Journal of Urology. 150: 1278-83. PMID 8371415 DOI: 10.1016/S0022-5347(17)35760-9  0.31
1993 Carter BS, Bova GS, Beaty TH, Steinberg GD, Childs B, Isaacs WB, Walsh PC. Hereditary prostate cancer: Epidemiologic and clinical features Journal of Urology. 150: 797-802. PMID 8345587 DOI: 10.1016/S0022-5347(17)35617-3  0.588
1992 Newmark JR, Hardy DO, Tonb DC, Carter BS, Epstein JI, Isaacs WB, Brown TR, Barrack ER. Androgen receptor gene mutations in human prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 89: 6319-23. PMID 1631125 DOI: 10.1073/Pnas.89.14.6319  0.428
1992 Pienta KJ, Murphy BC, Isaacs WB, Isaacs JT, Coffey DS. Effect of pentosan, a novel cancer chemotherapeutic agent, on prostate cancer cell growth and motility Prostate. 20: 233-241. PMID 1374181 DOI: 10.1002/Pros.2990200308  0.605
1991 Morton RA, Isaacs JT, Isaacs WB. Differential effects of growth factor antagonists on neoplastic and normal prostatic cells. The Prostate. 17: 327-36. PMID 2251224 DOI: 10.1002/Pros.2990170408  0.526
1991 Pienta KJ, Isaacs WB, Vindivich D, Coffey DS. The effects of basic fibroblast growth factor and suramin on cell motility and growth of rat prostate cancer cells Journal of Urology. 145: 199-202. PMID 1984091 DOI: 10.1016/S0022-5347(17)38291-5  0.676
1991 Carter BS, Ewing CM, Ward WS, Treiger BF, Aalders TW, Schalken JA, Epstein JI, Isaacs WB. Allelic loss of chromosomes 16q and 10q in human prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 87: 8751-5. PMID 1978938 DOI: 10.1073/Pnas.87.22.8751  0.447
1990 Isaacs WB, Isaacs JT, Kyprianou N, Burgers JK, Alexander RB, Partin AW, Mohler JL, Marshall FF, Coffey DS. New approaches to the evaluation of the metastatic ability of renal cancer and new approaches to chemotherapy European Urology. 18: 33-35. PMID 2226604 DOI: 10.1159/000463958  0.53
Show low-probability matches.