Simon W. Hayward - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Oncology, Cell Biology

172 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lanman NA, Meco E, Fitchev P, Kolliegbo AK, Broman MM, Filipovich Y, Kothandaraman H, Cresswell GM, Talaty P, Antoniak M, Brumer S, Glaser AP, Higgins AM, Helfand BT, Franco OE, ... ... Hayward SW, et al. Infiltrating lipid-rich macrophage subpopulations identified as a regulator of increasing prostate size in human benign prostatic hyperplasia. Biorxiv : the Preprint Server For Biology. PMID 38915654 DOI: 10.1101/2024.06.07.597992  0.424
2023 Singh P, Lanman NA, Kendall HLR, Wilson L, Long R, Franco OE, Buskin A, Miles CG, Hayward SW, Heer R, Robson CN. Human prostate organoid generation and the identification of prostate development drivers using inductive rodent tissues. Development (Cambridge, England). PMID 37376888 DOI: 10.1242/dev.201328  0.503
2023 Morales A, Greenberg M, Nardi F, Gil V, Hayward SW, Crawford SE, Franco OE. Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 921-934. PMID 36775561 DOI: 10.1038/s41374-021-00583-9  0.427
2022 Glaser A, Shi Z, Wei J, Lanman NA, Ladson-Gary S, Vickman RE, Franco OE, Crawford SE, Lilly Zheng S, Hayward SW, Isaacs WB, Helfand BT, Xu J. Shared Inherited Genetics of Benign Prostatic Hyperplasia and Prostate Cancer. European Urology Open Science. 43: 54-61. PMID 36353071 DOI: 10.1016/j.euros.2022.07.004  0.493
2022 Vickman RE, Franco OE, Hayward SW. Could TNF-antagonists be a novel treatment strategy for BPH patients? Cell Stress. 6: 65-67. PMID 36072128 DOI: 10.15698/cst2022.06.268  0.325
2022 Kakarla M, ChallaSivaKanaka S, Dufficy MF, Gil V, Filipovich Y, Vickman R, Crawford SE, Hayward SW, Franco OE. Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer. Cancers. 14. PMID 35565468 DOI: 10.3390/cancers14092336  0.513
2022 Vickman RE, Aaron-Brooks L, Zhang R, Lanman NA, Lapin B, Gil V, Greenberg M, Sasaki T, Cresswell GM, Broman MM, Paez JS, Petkewicz J, Talaty P, Helfand BT, Glaser AP, ... ... Hayward SW, et al. TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease. Nature Communications. 13: 2133. PMID 35440548 DOI: 10.1038/s41467-022-29719-1  0.433
2022 ChallaSivaKanaka S, Vickman RE, Kakarla M, Hayward SW, Franco OE. Fibroblast heterogeneity in prostate carcinogenesis. Cancer Letters. 525: 76-83. PMID 34715252 DOI: 10.1016/j.canlet.2021.10.028  0.531
2021 Morales A, Greenberg M, Nardi F, Gil V, Hayward SW, Crawford SE, Franco OE. Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 33824421 DOI: 10.1038/s41374-021-00583-9  0.419
2020 Vickman RE, Franco OE, Moline DC, Vander Griend DJ, Thumbikat P, Hayward SW. The role of the androgen receptor in prostate development and benign prostatic hyperplasia: A review. Asian Journal of Urology. 7: 191-202. PMID 32742923 DOI: 10.1016/J.Ajur.2019.10.003  0.553
2020 Frankenstein Z, Basanta D, Franco OE, Gao Y, Javier RA, Strand DW, Lee M, Hayward SW, Ayala G, Anderson ARA. Stromal reactivity differentially drives tumour cell evolution and prostate cancer progression. Nature Ecology & Evolution. PMID 32393869 DOI: 10.1038/S41559-020-1157-Y  0.523
2020 Hayward SW. Immunotherapeutic Response in Tumors Is Affected by Microenvironmental ROS. Cancer Research. 80: 1799-1800. PMID 32366527 DOI: 10.1158/0008-5472.Can-20-0590  0.303
2020 Hepburn AC, Curry EL, Moad M, Steele RE, Franco OE, Wilson L, Singh P, Buskin A, Crawford SE, Gaughan L, Mills IG, Hayward SW, Robson CN, Heer R. Propagation of human prostate tissue from induced pluripotent stem cells. Stem Cells Translational Medicine. PMID 32170918 DOI: 10.1002/Sctm.19-0286  0.571
2020 Morales A, Gil V, Crawford S, Hayward S, Franco O. Mp51-07 Loss Of Ephrin Signaling Alters The Lipid Rheostat Associated With Prostate Cancer Racial Disparities The Journal of Urology. 203. DOI: 10.1097/Ju.0000000000000913.07  0.51
2020 Greenberg M, Gil V, Fitchev P, Nardi, Evanston F, Daroach D, Franco O, Hayward S, Vickman R, Su X, Nicholson T, Theberge A, Crawford* S. MP51-15 PERIPROSTATIC FAT INDUCES CENTROSOMAL AMPLIFICATION IN THE PROSTATE CANCER MICROENVIRONMENT The Journal of Urology. 203: e769-e770. DOI: 10.1097/Ju.0000000000000913.015  0.553
2020 Vickman R, Cresswell G, Lanman N, Broman M, Franco O, Helfand B, Glaser A, Katz L, Petkewicz J, Talaty P, Crawford S, Ratliff T, Hayward* S. MP06-11 CHARACTERIZATION OF INFLAMMATORY CELLS IN HUMAN BENIGN PROSTATIC HYPERPLASIA The Journal of Urology. 203: e55. DOI: 10.1097/Ju.0000000000000820.011  0.556
2020 Vickman RE, Franco OE, Hayward SW. Contributions of carcinoma-associated fibroblasts to the prostate cancer microenvironment Current Opinion in Endocrine and Metabolic Research. 10: 1-6. DOI: 10.1016/J.Coemr.2020.01.004  0.603
2019 Vickman RE, Broman MM, Lanman NA, Franco OE, Sudyanti PAG, Ni Y, Ji Y, Helfand BT, Petkewicz J, Paterakos MC, Crawford SE, Ratliff TL, Hayward SW. Heterogeneity of human prostate carcinoma-associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment. The Prostate. PMID 31763714 DOI: 10.1002/Pros.23929  0.57
2019 Nardi F, Fitchev P, Brooks KM, Franco OE, Cheng K, Hayward SW, Welte MA, Crawford SE. Lipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31409893 DOI: 10.1038/S41374-019-0296-8  0.447
2019 Aaron-Brooks LM, Sasaki T, Vickman RE, Wei L, Franco OE, Ji Y, Crawford SE, Hayward SW. Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse. The Prostate. PMID 30999385 DOI: 10.1002/Pros.23809  0.482
2019 Nardi F, Franco OE, Fitchev P, Morales A, Vickman RE, Hayward SW, Crawford SE. DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130. Scientific Reports. 9: 3035. PMID 30816200 DOI: 10.1038/S41598-019-39537-Z  0.518
2018 Sasaki T, Franco OE, Ohishi K, Filipovich Y, Ishii K, Crawford SE, Takahashi N, Katayama N, Sugimura Y, Hayward SW. Tyrosine kinase inhibitor therapy prescribed for non-urologic diseases can modify PSA titers in urology patients. The Prostate. PMID 30370673 DOI: 10.1002/Pros.23730  0.458
2018 Nardi F, Fitchev P, Franco OE, Ivanisevic J, Scheibler A, Hayward SW, Brendler CB, Welte MA, Crawford SE. PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer associated fibroblasts. Journal of Cell Science. PMID 29792311 DOI: 10.1242/Jcs.213579  0.438
2018 Vickman RE, Broman MM, Atallah NM, Sudyanti A, Franco OE, Ratliff TL, Hayward SW. Abstract 5075: Single-cell RNAseq of human prostate cancer-associated fibroblasts reveals distinct subpopulations that may promote inflammatory cell recruitment to the tumor microenvironment Tumor Biology. DOI: 10.1158/1538-7445.Am2018-5075  0.571
2018 Hepburn A, Moad M, Curry E, Wilson L, Steele R, Franco O, Singh P, Mills I, Hayward S, Robson C, Heer R. Generation of human prostate tissue from induced pluripotent stem cells European Urology Supplements. 17: e2548. DOI: 10.1016/S1569-9056(18)33027-6  0.51
2018 Sasaki T, Franco O, Filipovich Y, Aaron L, Fitchev P, Strand D, Crawford S, Hayward S. MP45-14 LONG-TERM LEPTIN ADMINISTRATION REDUCES PROSTATIC EPITHELIAL HYPERPLASIA IN THE OB/OB MOUSE MODEL Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.1453  0.487
2017 Erdogan B, Ao M, White LM, Means AL, Brewer BM, Yang L, Washington MK, Shi C, Franco OE, Weaver AM, Hayward SW, Li D, Webb DJ. Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin. The Journal of Cell Biology. PMID 29021221 DOI: 10.1083/Jcb.201704053  0.762
2017 Sasaki T, Franco OE, Hayward SW. Interaction of prostate carcinoma-associated fibroblasts with human epithelial cell lines in vivo. Differentiation; Research in Biological Diversity. 96: 40-48. PMID 28779656 DOI: 10.1016/J.Diff.2017.07.002  0.547
2017 Na R, Helfand BT, Chen H, Conran CA, Crawford SE, Hayward SW, Tammela TLJ, Hoffman-Bolton J, Zheng SL, Walsh PC, Schleutker J, Platz EA, Isaacs WB, Xu J. A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). The Prostate. PMID 28656603 DOI: 10.1002/Pros.23380  0.468
2017 Nash C, Boufaied N, Mills IG, Franco OE, Hayward SW, Thomson AA. Genome-wide analysis of AR binding and comparison with transcript expression in primary human fetal prostate fibroblasts and cancer associated fibroblasts. Molecular and Cellular Endocrinology. PMID 28483704 DOI: 10.1016/J.Mce.2017.05.006  0.555
2017 Franco O, Javier R, Brady M, Crawford S, Hayward S. Mp17-18 Peri-Prostatic Fat (Ppf) Secretome In Bph Progression The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.607  0.538
2017 Sasaki T, Franco O, Aaron L, Javier R, Filipovich Y, Crawford S, Hayward S. MP17-15 LONG-TERM LEPTIN TREATMENT RESULTS IN A REDUCTION IN PROSTATIC EPITHELIAL HYPERPLASIA IN THE OBOB MOUSE MODEL Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.604  0.477
2017 Filipovich Y, Franco O, Hayward S. Mp83-16 Exploring 2D And 3D Culture On Responses To Combinatorial Drug Therapy In Human Prostate Cell Lines The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.2584  0.417
2016 Yang S, Jiang M, Grabowska MM, Li J, Connelly ZM, Zhang J, Hayward SW, Cates JM, Han G, Yu X. Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo. Oncotarget. PMID 27611945 DOI: 10.18632/Oncotarget.11879  0.583
2016 Henke A, Franco OE, Stewart GD, Riddick AC, Katz E, Hayward SW, Thomson AA. Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90. Cancers. 8. PMID 27563925 DOI: 10.3390/Cancers8090077  0.506
2016 Aaron L, Franco OE, Hayward SW. Review of Prostate Anatomy and Embryology and the Etiology of Benign Prostatic Hyperplasia. The Urologic Clinics of North America. 43: 279-88. PMID 27476121 DOI: 10.1016/J.Ucl.2016.04.012  0.57
2016 Franco OE, Tyson DR, Konvinse KC, Udyavar AR, Estrada L, Quaranta V, Crawford SE, Hayward SW. Altered TGF-α/β signaling drives cooperation between breast cancer cell populations. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27383183 DOI: 10.1096/Fj.201500187Rr  0.369
2016 Austin DC, Strand DW, Love HL, Franco OE, Grabowska MM, Miller NL, Hameed O, Clark PE, Matusik RJ, Jin RJ, Hayward SW. NF-κB and androgen receptor variant 7 induce expression of SRD5A isoforms and confer 5ARI resistance. The Prostate. PMID 27197599 DOI: 10.1002/Pros.23195  0.505
2016 Bianchi-Frias D, Basom R, Delrow JJ, Coleman IM, Dakhova O, Qu X, Fang M, Franco OE, Ericson NG, Bielas JH, Hayward SW, True L, Morrissey C, Brown L, Bhowmick NA, et al. Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations. Molecular Cancer Research : McR. PMID 26753621 DOI: 10.1158/1541-7786.Mcr-15-0330  0.497
2016 Franco OE, Javier R, Crawford SE, Ayala GE, Hayward SW. Mp62-14 Activation Of Aberrant Androgen Receptor Signaling In Carcinoma Associated Fibroblasts Induces Prostate Cancer Progression The Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.922  0.547
2016 Pruitt J, Petkewicz J, Lapin B, Franco OE, Helfand BT, Brendler CB, Wang C, Hayward SW. MP35-02 BENIGN PROSTATIC HYPERPLASIA AND AUTOIMMUNE INFLAMMATORY DISEASES COINCIDENCE AND CONSEQUENCES Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.1594  0.369
2015 Austin DC, Strand DW, Love HL, Franco OE, Jang A, Grabowska MM, Miller NL, Hameed O, Clark PE, Fowke JH, Matusik RJ, Jin RJ, Hayward SW. NF-κB and androgen receptor variant expression correlate with human BPH progression. The Prostate. PMID 26709083 DOI: 10.1002/Pros.23140  0.537
2015 Grabowska MM, Kelly SM, Reese AL, Cates JM, Case TC, Zhang J, DeGraff DJ, Strand DW, Miller NL, Clark PE, Hayward SW, Gronostajski RM, Anderson PD, Matusik RJ. Nfib regulates transcriptional networks that control the development of prostatic hyperplasia. Endocrinology. en20151312. PMID 26677878 DOI: 10.1210/En.2015-1312  0.584
2015 Strand DW, Aaron L, Henry G, Franco OE, Hayward SW. Isolation and analysis of discreet human prostate cellular populations. Differentiation; Research in Biological Diversity. PMID 26546040 DOI: 10.1016/J.Diff.2015.10.013  0.524
2015 Osuala KO, Sameni M, Shah S, Aggarwal N, Simonait ML, Franco OE, Hong Y, Hayward SW, Behbod F, Mattingly RR, Sloane BF. Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration. Bmc Cancer. 15: 584. PMID 26268945 DOI: 10.1186/S12885-015-1576-3  0.357
2015 Huynh TP, Barwe SP, Lee SJ, McSpadden R, Franco OE, Hayward SW, Damoiseaux R, Grubbs SS, Petrelli NJ, Rajasekaran AK. Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression. Plos One. 10: e0122442. PMID 25836370 DOI: 10.1371/Journal.Pone.0122442  0.403
2015 Nolan KD, Franco OE, Hance MW, Hayward SW, Isaacs JS. Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion. The Journal of Biological Chemistry. 290: 8271-82. PMID 25670862 DOI: 10.1074/Jbc.M115.637496  0.561
2015 Ao M, Brewer BM, Yang L, Franco Coronel OE, Hayward SW, Webb DJ, Li D. Stretching fibroblasts remodels fibronectin and alters cancer cell migration. Scientific Reports. 5: 8334. PMID 25660754 DOI: 10.1038/Srep08334  0.755
2015 Frankenstein Z, Basanta D, Franco O, Hayward S, Ayala G, Anderson A. Abstract B2-53: The significance of stromal reactivity in shaping prostate cancer evolution and the prognosis: An integrated approach Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B2-53  0.537
2015 Frankenstein Z, Basanta D, Franco O, Strand D, Hayward S, Ayala G, Anderson A. Abstract PR15: The prognostic power of stromal reactivity: An integrated approach to prostate cancer evolution Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-Pr15  0.545
2015 Nolan KD, Hance MW, Franco OE, Hayward SW, Isaacs JS. Abstract 1448: Dynamic chromatin modification by tumor secreted Hsp90 modulates EMT and tumor invasion Cancer Research. 75: 1448-1448. DOI: 10.1158/1538-7445.Am2015-1448  0.446
2014 Jin R, Yamashita H, Yu X, Wang J, Franco OE, Wang Y, Hayward SW, Matusik RJ. Inhibition of NF-kappa B signaling restores responsiveness of castrate-resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor-variant expression. Oncogene. PMID 25220414 DOI: 10.1038/Onc.2014.302  0.531
2014 Yu X, Cates JM, Morrissey C, You C, Grabowska MM, Zhang J, DeGraff DJ, Strand DW, Franco OE, Lin-Tsai O, Hayward SW, Matusik RJ. SOX2 expression in the developing, adult, as well as, diseased prostate. Prostate Cancer and Prostatic Diseases. 17: 301-9. PMID 25091041 DOI: 10.1038/Pcan.2014.29  0.577
2014 Singh M, Jha R, Melamed J, Shapiro E, Hayward SW, Lee P. Stromal androgen receptor in prostate development and cancer. The American Journal of Pathology. 184: 2598-607. PMID 25088980 DOI: 10.1016/J.Ajpath.2014.06.022  0.615
2014 DeGraff DJ, Grabowska MM, Case TC, Yu X, Herrick MK, Hayward WJ, Strand DW, Cates JM, Hayward SW, Gao N, Walter MA, Buttyan R, Yi Y, Kaestner KH, Matusik RJ. FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 726-39. PMID 24840332 DOI: 10.1038/Labinvest.2014.64  0.598
2014 San Martin R, Barron DA, Tuxhorn JA, Ressler SJ, Hayward SW, Shen X, Laucirica R, Wheeler TM, Gutierrez C, Ayala GE, Ittmann M, Rowley DR. Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis. The American Journal of Pathology. 184: 1860-70. PMID 24713391 DOI: 10.1016/J.Ajpath.2014.02.021  0.491
2014 Lin-Tsai O, Clark PE, Miller NL, Fowke JH, Hameed O, Hayward SW, Strand DW. Surgical intervention for symptomatic benign prostatic hyperplasia is correlated with expression of the AP-1 transcription factor network. The Prostate. 74: 669-79. PMID 24500928 DOI: 10.1002/Pros.22785  0.517
2014 Hansen AG, Arnold SA, Jiang M, Palmer TD, Ketova T, Merkel A, Pickup M, Samaras S, Shyr Y, Moses HL, Hayward SW, Sterling JA, Zijlstra A. ALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to bone. Cancer Research. 74: 1404-15. PMID 24385212 DOI: 10.1158/0008-5472.Can-13-1296  0.582
2013 Xiang Y, Qiu Q, Jiang M, Jin R, Lehmann BD, Strand DW, Jovanovic B, DeGraff DJ, Zheng Y, Yousif DA, Simmons CQ, Case TC, Yi J, Cates JM, Virostko J, ... ... Hayward SW, et al. SPARCL1 suppresses metastasis in prostate cancer. Molecular Oncology. 7: 1019-30. PMID 23916135 DOI: 10.1016/J.Molonc.2013.07.008  0.489
2013 Moad M, Pal D, Hepburn AC, Williamson SC, Wilson L, Lako M, Armstrong L, Hayward SW, Franco OE, Cates JM, Fordham SE, Przyborski S, Carr-Wilkinson J, Robson CN, Heer R. A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells. European Urology. 64: 753-61. PMID 23582880 DOI: 10.1016/J.Eururo.2013.03.054  0.504
2013 Strand DW, DeGraff DJ, Jiang M, Sameni M, Franco OE, Love HD, Hayward WJ, Lin-Tsai O, Wang AY, Cates JM, Sloane BF, Matusik RJ, Hayward SW. Deficiency in metabolic regulators PPARγ and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration. The American Journal of Pathology. 182: 449-59. PMID 23219716 DOI: 10.1016/J.Ajpath.2012.10.007  0.534
2013 Orr B, Grace OC, Brown P, Riddick AC, Stewart GD, Franco OE, Hayward SW, Thomson AA. Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1. Disease Models & Mechanisms. 6: 530-6. PMID 23136397 DOI: 10.1242/Dmm.010355  0.597
2013 Pruitt FL, He Y, Franco OE, Jiang M, Cates JM, Hayward SW. Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium. The Prostate. 73: 476-88. PMID 22996917 DOI: 10.1002/Pros.22589  0.676
2013 Hance MW, Nolan K, Gopal U, Bohonowych JE, Jezierska-Drutel A, Neumann CA, Liu H, Isla GP, Franco OE, Hayward SW, Isaacs JS. Abstract A74: Tumor secreted Hsp90 initiates tumor growth and the epithelial to mesenchymal transition (EMT) in prostate cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A74  0.553
2012 Franco OE, Hayward SW. Targeting the tumor stroma as a novel therapeutic approach for prostate cancer. Advances in Pharmacology (San Diego, Calif.). 65: 267-313. PMID 22959029 DOI: 10.1016/B978-0-12-397927-8.00009-9  0.482
2012 Strand DW, Jiang M, Murphy TA, Yi Y, Konvinse KC, Franco OE, Wang Y, Young JD, Hayward SW. PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation. Cell Death & Disease. 3: e361. PMID 22874998 DOI: 10.1038/Cddis.2012.99  0.532
2012 Wang H, Jiang M, Cui H, Chen M, Buttyan R, Hayward SW, Hai T, Wang Z, Yan C. The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor. Molecular and Cellular Biology. 32: 3190-202. PMID 22665497 DOI: 10.1128/Mcb.00159-12  0.523
2012 Ricke EA, Williams K, Lee YF, Couto S, Wang Y, Hayward SW, Cunha GR, Ricke WA. Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis. Carcinogenesis. 33: 1391-8. PMID 22535887 DOI: 10.1093/Carcin/Bgs153  0.599
2012 Anderson PD, McKissic SA, Logan M, Roh M, Franco OE, Wang J, Doubinskaia I, van der Meer R, Hayward SW, Eischen CM, Eltoum IE, Abdulkadir SA. Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis. The Journal of Clinical Investigation. 122: 1907-19. PMID 22484818 DOI: 10.1172/Jci58540  0.503
2012 Li X, Sterling JA, Fan KH, Vessella RL, Shyr Y, Hayward SW, Matrisian LM, Bhowmick NA. Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions. Molecular Cancer Research : McR. 10: 494-503. PMID 22290877 DOI: 10.1158/1541-7786.Mcr-11-0506  0.578
2012 Basanta D, Scott JG, Fishman MN, Ayala G, Hayward SW, Anderson AR. Investigating prostate cancer tumour-stroma interactions: clinical and biological insights from an evolutionary game. British Journal of Cancer. 106: 174-81. PMID 22134510 DOI: 10.1038/Bjc.2011.517  0.549
2012 Orr B, Riddick AC, Stewart GD, Anderson RA, Franco OE, Hayward SW, Thomson AA. Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate. Oncogene. 31: 1130-42. PMID 21804603 DOI: 10.1038/Onc.2011.312  0.599
2012 Anderson PD, McKissic SA, Logan M, Roh M, Franco O, Wang J, Doubinskaia I, Meer Rvd, Hayward S, Eischen C, Eltoum IA, Abdulkadir SA. Abstract 2983: Nkx3.1 and c-Myc co-regulate shared target genes involved in prostate cancer Cancer Research. 72: 2983-2983. DOI: 10.1158/1538-7445.Am2012-2983  0.512
2011 Jiang M, Strand DW, Franco OE, Clark PE, Hayward SW. PPARγ: a molecular link between systemic metabolic disease and benign prostate hyperplasia. Differentiation; Research in Biological Diversity. 82: 220-36. PMID 21645960 DOI: 10.1016/J.Diff.2011.05.008  0.458
2011 Kiskowski MA, Jackson RS, Banerjee J, Li X, Kang M, Iturregui JM, Franco OE, Hayward SW, Bhowmick NA. Role for stromal heterogeneity in prostate tumorigenesis. Cancer Research. 71: 3459-70. PMID 21444670 DOI: 10.1158/0008-5472.Can-10-2999  0.522
2011 Franco OE, Jiang M, Strand DW, Peacock J, Fernandez S, Jackson RS, Revelo MP, Bhowmick NA, Hayward SW. Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis. Cancer Research. 71: 1272-81. PMID 21303979 DOI: 10.1158/0008-5472.Can-10-3142  0.536
2011 Sun H, Wang Y, Chinnam M, Zhang X, Hayward SW, Foster BA, Nikitin AY, Wills M, Goodrich DW. E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 704-9. PMID 21187395 DOI: 10.1073/Pnas.1015027108  0.444
2011 Orr B, Vanpoucke G, Grace OC, Smith L, Anderson RA, Riddick AC, Franco OE, Hayward SW, Thomson AA. Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia. The Prostate. 71: 305-17. PMID 20812209 DOI: 10.1002/Pros.21244  0.582
2011 Li X, Sterling JA, Mundy GR, Hayward SW, Matrisian LM, Bhowmick NA. Abstract 527: Loss of TGF-β responsiveness in stromal cells of the prostate facilitates early prostate cancer bone lesion development Cancer Research. 71: 527-527. DOI: 10.1158/1538-7445.Am2011-527  0.568
2011 Basanta D, Hashim AI, Gillies RJ, Gatenby RA, Ayala GE, Hayward SW, Anderson AR. Abstract 34: Microenvironmental independence or co-option: How tumour-stromal interactions influence prostate cancer lethal outcomes Cancer Research. 71: 34-34. DOI: 10.1158/1538-7445.Am2011-34  0.546
2011 Basanta D, Scott JG, Fishman MN, Ayala GE, Hayward SW, Anderson ARA. Investigating prostate cancer tumour-stroma interactions – clinical and biological insights from an evolutionary game Nature Precedings. 6: 1-1. DOI: 10.1038/Npre.2011.6385.1  0.566
2010 Barron DA, Strand DW, Ressler SJ, Dang TD, Hayward SW, Yang F, Ayala GE, Ittmann M, Rowley DR. TGF-β1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse. Plos One. 5: e13751. PMID 21060787 DOI: 10.1371/Journal.Pone.0013751  0.518
2010 Hayward SW. Preclinical assessment of fibroblast activation protein as a target for antitumor therapy. Future Oncology (London, England). 6: 347-9. PMID 20222791 DOI: 10.2217/Fon.10.8  0.329
2010 Strand DW, Franco OE, Basanta D, Anderson AR, Hayward SW. Perspectives on tissue interactions in development and disease. Current Molecular Medicine. 10: 95-112. PMID 20205682 DOI: 10.2174/156652410791065363  0.325
2010 Wang J, Kim J, Roh M, Franco OE, Hayward SW, Wills ML, Abdulkadir SA. Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma. Oncogene. 29: 2477-87. PMID 20140016 DOI: 10.1038/Onc.2010.10  0.512
2010 Jiang M, Strand DW, Fernandez S, He Y, Yi Y, Birbach A, Qiu Q, Schmid J, Tang DG, Hayward SW. Functional remodeling of benign human prostatic tissues in vivo by spontaneously immortalized progenitor and intermediate cells. Stem Cells (Dayton, Ohio). 28: 344-56. PMID 20020426 DOI: 10.1002/Stem.284  0.676
2010 Jiang M, Jerome WG, Hayward SW. Autophagy in nuclear receptor PPARgamma-deficient mouse prostatic carcinogenesis. Autophagy. 6: 175-6. PMID 20009560 DOI: 10.4161/Auto.6.1.10700  0.521
2010 Tanaka ST, Ishii K, Demarco RT, Pope JC, Brock JW, Hayward SW. Endodermal Origin of Bladder Trigone Inferred From Mesenchymal-Epithelial Interaction Journal of Urology. 183: 386-391. PMID 19914648 DOI: 10.1016/J.Juro.2009.08.107  0.52
2010 Franco OE, Shaw AK, Strand DW, Hayward SW. Cancer associated fibroblasts in cancer pathogenesis. Seminars in Cell & Developmental Biology. 21: 33-9. PMID 19896548 DOI: 10.1016/J.Semcdb.2009.10.010  0.422
2010 Jiang M, Fernandez S, Jerome WG, He Y, Yu X, Cai H, Boone B, Yi Y, Magnuson MA, Roy-Burman P, Matusik RJ, Shappell SB, Hayward SW. Disruption of PPARγ signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy Cell Death and Differentiation. 17: 469-481. PMID 19834493 DOI: 10.1038/Cdd.2009.148  0.616
2010 Wang J, Kim J, Roh M, Franco OE, Martinez E, Hayward SW, Wills ML, Abdulkadir SA. Abstract 3239: Synergy of PIM1 kinase with c-MYC in prostate cancer Cancer Research. 70: 3239-3239. DOI: 10.1158/1538-7445.Am10-3239  0.502
2010 Jackson RS, Kiskowski M, Li X, Banerjee J, Hayward SW, Bhowmick NA. Abstract 1428: Necessary contribution of wild-type stroma to prostate tumorigenesis Cancer Research. 70: 1428-1428. DOI: 10.1158/1538-7445.Am10-1428  0.522
2009 Weier HU, Kwan J, Lu CM, Ito Y, Wang M, Baumgartner A, Hayward SW, Weier JF, Zitzelsberger HF. Kinase expression and chromosomal rearrangements in papillary thyroid cancer tissues: investigations at the molecular and microscopic levels. Journal of Physiology and Pharmacology : An Official Journal of the Polish Physiological Society. 60: 47-55. PMID 20083851 DOI: 10.2172/983010  0.322
2009 Love HD, Booton SE, Boone BE, Breyer JP, Koyama T, Revelo MP, Shappell SB, Smith JR, Hayward SW. Androgen regulated genes in human prostate xenografts in mice: relation to BPH and prostate cancer. Plos One. 4: e8384. PMID 20027305 DOI: 10.1371/Journal.Pone.0008384  0.577
2009 Basanta D, Strand DW, Lukner RB, Franco OE, Cliffel DE, Ayala GE, Hayward SW, Anderson AR. The role of transforming growth factor-beta-mediated tumor-stroma interactions in prostate cancer progression: an integrative approach. Cancer Research. 69: 7111-20. PMID 19706777 DOI: 10.1158/0008-5472.Can-08-3957  0.489
2009 Anumanthan G, Tanaka ST, Adams CM, Thomas JC, Wills ML, Adams MC, Hayward SW, Matusik RJ, Bhowmick NA, Brock JW, Pope JC. Bladder stromal loss of transforming growth factor receptor II decreases fibrosis after bladder obstruction. The Journal of Urology. 182: 1775-80. PMID 19692014 DOI: 10.1016/J.Juro.2009.05.126  0.312
2009 Li H, Jiang M, Honorio S, Patrawala L, Jeter CR, Calhoun-Davis T, Hayward SW, Tang DG. Methodologies in assaying prostate cancer stem cells. Methods in Molecular Biology (Clifton, N.J.). 568: 85-138. PMID 19582423 DOI: 10.1007/978-1-59745-280-9_7  0.439
2009 Higgins LH, Withers HG, Garbens A, Love HD, Magnoni L, Hayward SW, Moyes CD. Hypoxia and the metabolic phenotype of prostate cancer cells. Biochimica Et Biophysica Acta. 1787: 1433-1443. PMID 19524545 DOI: 10.1016/J.Bbabio.2009.06.003  0.413
2009 Li X, Wang Y, Sharif-Afshar AR, Uwamariya C, Yi A, Ishii K, Hayward SW, Matusik RJ, Bhowmick NA. Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-beta signaling. Differentiation; Research in Biological Diversity. 77: 95-102. PMID 19281768 DOI: 10.1016/J.Diff.2008.09.012  0.583
2009 Chu JH, Yu S, Hayward SW, Chan FL. Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer. The Prostate. 69: 428-42. PMID 19107869 DOI: 10.1002/Pros.20897  0.581
2008 Li X, Placencio V, Iturregui JM, Uwamariya C, Sharif-Afshar AR, Koyama T, Hayward SW, Bhowmick NA. Prostate tumor progression is mediated by a paracrine TGF-β/Wnt3a signaling axis Oncogene. 27: 7118-7130. PMID 18724388 DOI: 10.1038/Onc.2008.293  0.538
2008 Thomas JC, Oottamasathien S, Makari JH, Honea L, Sharif-Afshar AR, Wang Y, Adams C, Wills ML, Bhowmick NA, Adams MC, Brock JW, Hayward SW, Matusik RJ, Pope JC. Temporal-spatial protein expression in bladder tissue derived from embryonic stem cells. The Journal of Urology. 180: 1784-9. PMID 18721943 DOI: 10.1016/J.Juro.2008.03.098  0.313
2008 Anumanthan G, Makari JH, Honea L, Thomas JC, Wills ML, Bhowmick NA, Adams MC, Hayward SW, Matusik RJ, Brock JW, Pope JC. Directed differentiation of bone marrow derived mesenchymal stem cells into bladder urothelium. The Journal of Urology. 180: 1778-83. PMID 18721942 DOI: 10.1016/J.Juro.2008.04.076  0.3
2008 Bhatia B, Jiang M, Suraneni M, Patrawala L, Badeaux M, Schneider-Broussard R, Multani AS, Jeter CR, Calhoun-Davis T, Hu L, Hu J, Tsavachidis S, Zhang W, Chang S, Hayward SW, et al. Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. The Journal of Biological Chemistry. 283: 27957-72. PMID 18662989 DOI: 10.1074/Jbc.M803467200  0.476
2008 Roh M, Franco OE, Hayward SW, van der Meer R, Abdulkadir SA. A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells. Plos One. 3: e2572. PMID 18596907 DOI: 10.1371/Journal.Pone.0002572  0.483
2008 Placencio VR, Sharif-Afshar AR, Li X, Huang H, Uwamariya C, Neilson EG, Shen MM, Matusik RJ, Hayward SW, Bhowmick NA. Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity. Cancer Research. 68: 4709-18. PMID 18559517 DOI: 10.1158/0008-5472.Can-07-6289  0.595
2008 Jin RJ, Lho Y, Wang Y, Ao M, Revelo MP, Hayward SW, Wills ML, Logan SK, Zhang P, Matusik RJ. Down-regulation of p57Kip2 induces prostate cancer in the mouse. Cancer Research. 68: 3601-8. PMID 18483241 DOI: 10.1158/0008-5472.Can-08-0073  0.804
2008 Mullins C, Lucia MS, Hayward SW, Lee JY, Levitt JM, Lin VK, Liu BC, Chinnaiyan AM, Rubin MA, Slawin K, Star RA, Getzenberg RH. A comprehensive approach toward novel serum biomarkers for benign prostatic hyperplasia: the MPSA Consortium. The Journal of Urology. 179: 1243-56. PMID 18280515 DOI: 10.1016/J.Juro.2007.11.049  0.524
2007 Vanpoucke G, Orr B, Grace OC, Chan R, Ashley GR, Williams K, Franco OE, Hayward SW, Thomson AA. Transcriptional profiling of inductive mesenchyme to identify molecules involved in prostate development and disease. Genome Biology. 8: R213. PMID 17922897 DOI: 10.1186/Gb-2007-8-10-R213  0.546
2007 He Y, Franco OE, Jiang M, Williams K, Love HD, Coleman IM, Nelson PS, Hayward SW. Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression. Cancer Research. 67: 8188-97. PMID 17804732 DOI: 10.1158/0008-5472.Can-07-0418  0.622
2007 Oottamasathien S, Williams K, Franco OE, Wills ML, Thomas JC, Sharif-Afshar AR, DeMarco RT, Brock JW, Bhowmick NA, Hayward SW, Pope JC. Urothelial inhibition of transforming growth factor-beta in a bladder tissue recombination model. The Journal of Urology. 178: 1643-9. PMID 17707033 DOI: 10.1016/J.Juro.2007.03.163  0.317
2007 Ao M, Franco OE, Park D, Raman D, Williams K, Hayward SW. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Research. 67: 4244-53. PMID 17483336 DOI: 10.1158/0008-5472.Can-06-3946  0.764
2007 Oottamasathien S, Wang Y, Williams K, Franco OE, Wills ML, Thomas JC, Saba K, Sharif-Afshar AR, Makari JH, Bhowmick NA, DeMarco RT, Hipkens S, Magnuson M, Brock JW, Hayward SW, et al. Directed differentiation of embryonic stem cells into bladder tissue. Developmental Biology. 304: 556-66. PMID 17289017 DOI: 10.1016/J.Ydbio.2007.01.010  0.364
2007 Cannon GW, Mullins C, Lucia MS, Hayward SW, Lin V, Liu BC, Slawin K, Rubin MA, Getzenberg RH. A preliminary study of JM-27: a serum marker that can specifically identify men with symptomatic benign prostatic hyperplasia. The Journal of Urology. 177: 610-4; discussion 61. PMID 17222644 DOI: 10.1016/J.Juro.2006.09.023  0.51
2006 Ao M, Williams K, Bhowmick NA, Hayward SW. Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells. Cancer Research. 66: 8007-16. PMID 16912176 DOI: 10.1158/0008-5472.Can-05-4451  0.72
2006 Wang Y, Kasper S, Yuan J, Jin RJ, Zhang J, Ishii K, Wills ML, Hayward SW, Matusik RJ. Androgen-dependent prostate epithelial cell selection by targeting ARR(2)PBneo to the LPB-Tag model of prostate cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1074-88. PMID 16894353 DOI: 10.1038/Labinvest.3700463  0.569
2006 Oottamasathien S, Williams K, Franco OE, Thomas JC, Saba K, Bhowmick NA, Staack A, Demarco RT, Brock JW, Hayward SW, Pope JC. Bladder tissue formation from cultured bladder urothelium. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2795-801. PMID 16804891 DOI: 10.1002/Dvdy.20886  0.323
2006 Sun H, Chang Y, Schweers B, Dyer MA, Zhang X, Hayward SW, Goodrich DW. An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity. Molecular and Cellular Biology. 26: 1527-37. PMID 16449662 DOI: 10.1128/Mcb.26.4.1527-1537.2006  0.332
2006 Ricke WA, Ishii K, Ricke EA, Simko J, Wang Y, Hayward SW, Cunha GR. Steroid hormones stimulate human prostate cancer progression and metastasis. International Journal of Cancer. Journal International Du Cancer. 118: 2123-31. PMID 16331600 DOI: 10.1002/Ijc.21614  0.465
2005 Ricke WA, Wang Y, Kurita T, Hayward SW, Cunha GR. Hormonal and stromal regulation of normal and neoplastic prostatic growth. Progress in Molecular and Subcellular Biology. 40: 183-216. PMID 17153485 DOI: 10.1007/3-540-27671-8_8  0.529
2005 Joesting MS, Perrin S, Elenbaas B, Fawell SE, Rubin JS, Franco OE, Hayward SW, Cunha GR, Marker PC. Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer. Cancer Research. 65: 10423-30. PMID 16288033 DOI: 10.1158/0008-5472.Can-05-0824  0.627
2005 Wang Y, Xue H, Cutz JC, Bayani J, Mawji NR, Chen WG, Goetz LJ, Hayward SW, Sadar MD, Gilks CB, Gout PW, Squire JA, Cunha GR, Wang YZ. An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 1392-404. PMID 16155594 DOI: 10.1038/Labinvest.3700335  0.557
2005 Gao N, Ishii K, Mirosevich J, Kuwajima S, Oppenheimer SR, Roberts RL, Jiang M, Yu X, Shappell SB, Caprioli RM, Stoffel M, Hayward SW, Matusik RJ. Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. Development (Cambridge, England). 132: 3431-43. PMID 15987773 DOI: 10.1242/Dev.01917  0.605
2005 Ishii K, Shappell SB, Matusik RJ, Hayward SW. Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 1086-103. PMID 15980886 DOI: 10.1038/Labinvest.3700310  0.403
2005 Williams K, Fernandez S, Stien X, Ishii K, Love HD, Lau YF, Roberts RL, Hayward SW. Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype. The Prostate. 63: 369-84. PMID 15937962 DOI: 10.1002/Pros.20200  0.58
2005 Staack A, Hayward SW, Baskin LS, Cunha GR. Molecular, cellular and developmental biology of urothelium as a basis of bladder regeneration. Differentiation; Research in Biological Diversity. 73: 121-33. PMID 15901280 DOI: 10.1111/J.1432-0436.2005.00014.X  0.324
2005 Davis JN, McCabe MT, Hayward SW, Park JM, Day ML. Disruption of Rb/E2F pathway results in increased cyclooxygenase-2 expression and activity in prostate epithelial cells. Cancer Research. 65: 3633-42. PMID 15867358 DOI: 10.1158/0008-5472.Can-04-3129  0.574
2005 Cheng N, Bhowmick NA, Chytil A, Gorksa AE, Brown KA, Muraoka R, Arteaga CL, Neilson EG, Hayward SW, Moses HL. Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks. Oncogene. 24: 5053-68. PMID 15856015 DOI: 10.1038/Sj.Onc.1208685  0.389
2005 Wang Y, Revelo MP, Sudilovsky D, Cao M, Chen WG, Goetz L, Xue H, Sadar M, Shappell SB, Cunha GR, Hayward SW. Development and characterization of efficient xenograft models for benign and malignant human prostate tissue. The Prostate. 64: 149-59. PMID 15678503 DOI: 10.1002/Pros.20225  0.543
2004 Cunha GR, Ricke W, Thomson A, Marker PC, Risbridger G, Hayward SW, Wang YZ, Donjacour AA, Kurita T. Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development. The Journal of Steroid Biochemistry and Molecular Biology. 92: 221-36. PMID 15663986 DOI: 10.1016/J.Jsbmb.2004.10.017  0.597
2004 Jin RJ, Wang Y, Masumori N, Ishii K, Tsukamoto T, Shappell SB, Hayward SW, Kasper S, Matusik RJ. NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice. Cancer Research. 64: 5489-95. PMID 15289359 DOI: 10.1158/0008-5472.Can-03-3117  0.559
2004 Ishii K, Otsuka T, Iguchi K, Usui S, Yamamoto H, Sugimura Y, Yoshikawa K, Hayward SW, Hirano K. Evidence that the prostate-specific antigen (PSA)/Zn2+ axis may play a role in human prostate cancer cell invasion. Cancer Letters. 207: 79-87. PMID 15050736 DOI: 10.1016/J.Canlet.2003.09.029  0.596
2004 Jiang M, Shappell SB, Hayward SW. Approaches to understanding the importance and clinical implications of peroxisome proliferator-activated receptor gamma (PPARgamma) signaling in prostate cancer. Journal of Cellular Biochemistry. 91: 513-27. PMID 14755682 DOI: 10.1002/Jcb.10770  0.56
2004 Williams K, Ishii K, Hayward SW. 396: C-Myc Overexpression in Human Prostate Initiates Cancer in Vivo The Journal of Urology. 171: 104-104. DOI: 10.1016/S0022-5347(18)37658-4  0.543
2004 Donohoe JM, Pope JC, Bhowmick NA, Adams MC, Brock JW, Hayward SW. 171: Expression of Dominant Active Transforming Growth Factor-Beta Receptor in Fetal Rat Bladder Stromal Cells The Journal of Urology. 171: 45-46. DOI: 10.1016/S0022-5347(18)37433-0  0.341
2003 Cunha GR, Hayward SW, Wang YZ, Ricke WA. Role of the stromal microenvironment in carcinogenesis of the prostate. International Journal of Cancer. Journal International Du Cancer. 107: 1-10. PMID 12925950 DOI: 10.1002/Ijc.11335  0.61
2003 Hayward SW, Wang Y, Day ML. Rescue and isolation of Rb-deficient prostate epithelium by tissue recombination. Methods in Molecular Biology (Clifton, N.J.). 218: 17-33. PMID 12616709 DOI: 10.1385/1-59259-356-9:17  0.566
2003 Staack A, Kassis AP, Olshen A, Wang Y, Wu D, Carroll PR, Grossfeld GD, Cunha GR, Hayward SW. Quantitation of apoptotic activity following castration in human prostatic tissue in vivo. The Prostate. 54: 212-9. PMID 12518326 DOI: 10.1002/Pros.10179  0.557
2003 Wang Y, Sudilovsky D, Cao M, Chen WG, Goetz L, Xue H, Wang Y, Sadar M, Shappell S, Hayward SW, Cunha GR. Establishing efficient xenograft models of models of low-grade human prostate cancer European Urology Supplements. 2: 30. DOI: 10.1016/S1569-9056(03)90409-X  0.512
2003 Williams K, Ishii K, Hayward SW. Characterization of human prostatic epithelial cells from the transitional & peripheral zone infected with a retrovirus carrying the c-MYC proto-oncogene European Urology Supplements. 2: 1. DOI: 10.1016/S1569-9056(03)90380-0  0.494
2002 Cunha GR, Hayward SW, Wang YZ. Role of stroma in carcinogenesis of the prostate. Differentiation; Research in Biological Diversity. 70: 473-85. PMID 12492490 DOI: 10.1046/J.1432-0436.2002.700902.X  0.617
2002 Day KC, McCabe MT, Zhao X, Wang Y, Davis JN, Phillips J, Von Geldern M, Ried T, KuKuruga MA, Cunha GR, Hayward SW, Day ML. Rescue of embryonic epithelium reveals that the homozygous deletion of the retinoblastoma gene confers growth factor independence and immortality but does not influence epithelial differentiation or tissue morphogenesis. The Journal of Biological Chemistry. 277: 44475-84. PMID 12191999 DOI: 10.1074/Jbc.M205361200  0.552
2002 Kim MJ, Bhatia-Gaur R, Banach-Petrosky WA, Desai N, Wang Y, Hayward SW, Cunha GR, Cardiff RD, Shen MM, Abate-Shen C. Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Research. 62: 2999-3004. PMID 12036903  0.487
2002 Shou J, Soriano R, Hayward SW, Cunha GR, Williams PM, Gao WQ. Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 99: 2830-5. PMID 11880635 DOI: 10.1073/Pnas.052705299  0.588
2001 Cunha GR, Wang YZ, Hayward SW, Risbridger GP. Estrogenic effects on prostatic differentiation and carcinogenesis. Reproduction, Fertility and Development. 13: 285-296. PMID 11800167 DOI: 10.1071/Rd01010  0.569
2001 Wang Y, Hayward S, Cao M, Thayer K, Cunha G. Cell differentiation lineage in the prostate. Differentiation; Research in Biological Diversity. 68: 270-9. PMID 11776479 DOI: 10.1046/J.1432-0436.2001.680414.X  0.509
2001 Hsieh H-, Lersch RA, Callahan DE, Hayward S, Wong M, Clark OH, Weier HG. Monitoring signal transduction in cancer: cDNA microarray for semiquantitative analysis. Journal of Histochemistry and Cytochemistry. 49: 1057-1058. PMID 11457934 DOI: 10.1177/002215540104900814  0.329
2000 Li Y, Liu W, Hayward SW, Cunha GR, Baskin LS. Plasticity of the urothelial phenotype: effects of gastro-intestinal mesenchyme/stroma and implications for urinary tract reconstruction. Differentiation. 66: 126-135. PMID 11100903 DOI: 10.1046/J.1432-0436.2000.660207.X  0.353
2000 Liu W, Li Y, Hayward S, Cunha G, Baskin L. Diffusable growth factors induce bladder smooth muscle differentiation. In Vitro Cellular & Developmental Biology – Animal. 36: 476-484. PMID 11039497 DOI: 10.1290/1071-2690(2000)036<0476:Dgfibs>2.0.Co;2  0.382
2000 Hayward SW, Cunha GR. The prostate: development and physiology. Radiologic Clinics of North America. 38: 1-14. PMID 10664663 DOI: 10.1016/S0033-8389(05)70146-9  0.598
2000 Baskin LS, Hayward SW, DiSandro MS, Li YW, Cunha GR. Epithelial-mesenchymal interactions in the bladder. Implications for bladder augmentation. Advances in Experimental Medicine and Biology. 462: 49-61. PMID 10599413 DOI: 10.1007/978-1-4615-4737-2_5  0.315
1999 Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium Cancer Research. 59: 5002-5011. PMID 10519415 DOI: 10.1186/Bcr138  0.592
1999 Hayward SW, Haughney PC, Lopes ES, Danielpour D, Cunha GR. The rat prostatic epithelial cell line NRP-152 can differentiate in vivo in response to its stromal environment Prostate. 39: 205-212. PMID 10334110 DOI: 10.1002/(Sici)1097-0045(19990515)39:3<205::Aid-Pros9>3.0.Co;2-M  0.533
1999 Hayward SW, Zhang B, Wang Y, Cunha GR. Prostatic Epithelial Apoptosis Following Castration Does Not Require Epithelial Androgen Receptors The Journal of Urology. 51. DOI: 10.1097/00005392-199904010-00208  0.529
1998 Licht P, Hayes T, Tsai P, Cunha G, Kim H, Golbus M, Hayward S, Martin MC, Jaffe RB, Glickman SE. Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 1. Urogenital morphology and placental androgen production during fetal life. Journal of Reproduction and Fertility. 113: 105-16. PMID 9713383 DOI: 10.1530/Jrf.0.1130105  0.314
1998 Hayward SW, Haughney PC, Rosen MA, Greulich KM, Weier HU, Dahiya R, Cunha GR. Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model. Differentiation; Research in Biological Diversity. 63: 131-40. PMID 9697307 DOI: 10.1046/J.1432-0436.1998.6330131.X  0.527
1998 Haughney PC, Hayward SW, Dahiya R, Cunha GR. Species-Specific Detection of Growth Factor Gene Expression in Developing Murine Prostatic Tissue Biology of Reproduction. 59: 93-99. PMID 9674998 DOI: 10.1095/Biolreprod59.1.93  0.453
1998 Hayward SW, Grossfeld GD, Tlsty TD, Cunha GR. Genetic and epigenetic influences in prostatic carcinogenesis (review) International Journal of Oncology. 13: 35-47. PMID 9625801 DOI: 10.3892/Ijo.13.1.35  0.569
1998 Kopachik W, Hayward SW, Cunha GR. Expression of hepatocyte nuclear factor-3α in rat prostate, seminal vesicle, and bladder Developmental Dynamics. 211: 131-140. PMID 9489767 DOI: 10.1002/(Sici)1097-0177(199802)211:2<131::Aid-Aja2>3.0.Co;2-I  0.397
1998 Grossfeld GD, Hayward SW, Tlsty TD, Cunha GR. The role of stroma in prostatic carcinogenesis Endocrine-Related Cancer. 5: 253-270. DOI: 10.1677/Erc.0.0050253  0.62
1998 DiSANDRO MJ, Li Y, Baskin LS, Hayward S, Cunha G. Mesenchymal-epithelial interactions in bladder smooth muscle development: epithelial specificity. The Journal of Urology. 160: 1040-1046. DOI: 10.1016/S0022-5347(01)62694-6  0.302
1997 Hayward SW, Rosen MA, Cunha GR. Stromal–epithelial interactions in the normal and neoplastic prostate Bjui. 79: 18-26. PMID 9126066 DOI: 10.1111/J.1464-410X.1997.Tb16917.X  0.532
1997 Baskin LS, Sutherland RS, DiSandro MJ, Hayward SW, Lipschutz J, Cunha GR. The Effect of Testosterone on Androgen Receptors and Human Penile Growth The Journal of Urology. 158: 1113-1118. DOI: 10.1016/S0022-5347(01)64400-8  0.339
1996 Baskin LS, Hayward SW, Sutherland RA, DiSandro MJ, Thomson AA, Goodman J, Cunha GR. Mesenchymal-epithelial interactions in the bladder World Journal of Urology. 14: 301-309. PMID 8912470 DOI: 10.1007/Bf00184602  0.35
1996 Hayward SW, Baskin LS, Haughney PC, Foster BA, Cunha AR, Dahiya R, Prins GS, Cunha GR. Stromal development in the ventral prostate, anterior prostate and seminal vesicle of the rat. Acta Anatomica. 155: 94-103. PMID 8828707 DOI: 10.1159/000147794  0.518
1996 Hayward SW, Baskin LS, Haughney PC, Cunha AR, Foster BA, Dahiya R, Prins GS, Cunha GR. Epithelial development in the rat ventral prostate, anterior prostate and seminal vesicle. Acta Anatomica. 155: 81-93. PMID 8828706 DOI: 10.1159/000147793  0.569
1996 Cunha GR, Hayward SW, Dahiya R, Foster BA. Smooth muscle-epithelial interactions in normal and neoplastic prostatic development. Acta Anatomica. 155: 63-72. PMID 8811117 DOI: 10.1159/000147791  0.543
1996 Hayward SW, Brody JR, Cunha GR. An edgewise look at basal epithelial cells: Three-dimensional views of the rat prostate, mammary gland and salivary gland Differentiation. 60: 219-227. PMID 8765052 DOI: 10.1046/J.1432-0436.1996.6040219.X  0.551
1996 Hayward SW, Cunha GR, Dahiya R. Normal Development and Carcinogenesis of the Prostate Annals of the New York Academy of Sciences. 784: 50-62. PMID 8651606 DOI: 10.1111/J.1749-6632.1996.Tb16227.X  0.552
1996 Baskin LS, Hayward SW, Young P, Cunha GR. Role of Mesenchymal-Epithelial Interactions in Normal Bladder Development The Journal of Urology. 156: 1820-1827. DOI: 10.1016/S0022-5347(01)65545-9  0.312
1995 Hayward SW, Dahiya R, Cunha GR, Bartek J, Deshpande N, Narayan P. Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1 In Vitro Cellular & Developmental Biology – Animal. 31: 14-24. PMID 7535634 DOI: 10.1007/Bf02631333  0.549
1989 Deshpande N, Hallowes RC, Cox S, Mitchell I, Hayward S, Towler JM. Divergent effects of interferons on the growth of human benign prostatic hyperplasia cells in primary culture. The Journal of Urology. 141: 157-160. PMID 2462066 DOI: 10.1016/S0022-5347(17)40631-8  0.436
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