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Zixin Deng - Publications

Affiliations: 
School of Pharmaceutical Sciences Wuhan University, Wuhan Shi, Hubei Sheng, China 
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Year Citation  Score
2020 Lü J, Long Q, Zhao Z, Chen L, He W, Hong J, Liu K, Wang Y, Pang X, Deng Z, Tao M. Engineering the Erythromycin-Producing Strain HOE107 for the Heterologous Production of Polyketide Antibiotics. Frontiers in Microbiology. 11: 593217. PMID 33363524 DOI: 10.3389/fmicb.2020.593217  0.301
2020 Hu X, Li X, Sheng Y, Wang H, Li X, Ou Y, Deng Z, Bai L, Kang Q. -Aminophenylalanine Involved in the Biosynthesis of Antitumor Dnacin B1 for Quinone Moiety Formation. Molecules (Basel, Switzerland). 25. PMID 32932689 DOI: 10.3390/Molecules25184186  0.395
2020 Sun G, Hu C, Mei Q, Luo M, Chen X, Li Z, Liu Y, Deng Z, Zhang Z, Sun Y. Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nature Communications. 11: 4501. PMID 32908132 DOI: 10.1038/S41467-020-18336-5  0.32
2020 Zhai G, Wang W, Xu W, Sun G, Hu C, Wu X, Cong Z, Deng L, Shi Y, Leadlay PF, Song H, Hong K, Deng Z, Sun Y. Cross-module Enoylreduction in the Azalomycin F Polyketide Synthase. Angewandte Chemie (International Ed. in English). PMID 32865309 DOI: 10.1002/Anie.202011357  0.308
2020 Huang Q, Li J, Shi T, Liang J, Wang Z, Bai L, Deng Z, Zhao YL. The defense mechanism of phosphorothioated DNA under peroxynitrite-mediated oxidative stress. Acs Chemical Biology. PMID 32816442 DOI: 10.1021/Acschembio.0C00591  0.309
2020 Ou Y, Sheng Y, Hu X, Leng D, Huang J, Hu Z, Bai L, Deng Z, Kang Q, Wu Y. sp. nov., a new actinobacterium isolated from Moq. rhizosphere. International Journal of Systematic and Evolutionary Microbiology. PMID 32790600 DOI: 10.1099/Ijsem.0.004377  0.344
2020 He H, Bian G, Herbst-Gervasoni CJ, Mori T, Shinsky SA, Hou A, Mu X, Huang M, Cheng S, Deng Z, Christianson DW, Abe I, Liu T. Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases. Nature Communications. 11: 3958. PMID 32769971 DOI: 10.1038/S41467-020-17642-2  0.312
2020 Luo M, Tang L, Dong Y, Huang H, Deng Z, Sun Y. Antibacterial natural products lobophorin L and M from the marine-derived sp. 4506. Natural Product Research. 1-7. PMID 32713197 DOI: 10.1080/14786419.2020.1797730  0.31
2020 Kong L, Wang Q, Deng Z, You D. Characterization of a FAD-dependent halogenase XanH and engineering construction of multifunctional fusion halogenases. Applied and Environmental Microbiology. PMID 32651204 DOI: 10.1128/Aem.01225-20  0.364
2020 Kong L, Wang Q, Yang W, Shen J, Li Y, Zheng X, Wang L, Chu Y, Deng Z, Chooi YH, You D. Three recently diverging duplicated methyltransferases exhibit substrate-dependent regioselectivity essential for xantholipin biosynthesis. Acs Chemical Biology. PMID 32649177 DOI: 10.1021/Acschembio.0C00296  0.389
2020 Tao M, Xu M, Zhang F, Cheng Z, Bashiri G, Wang J, Hong J, Wang Y, Xu L, Chen X, Huang SX, Lin S, Deng Z. Functional genome mining reveals a novel class V lanthipeptide containing a D-amino acid introduced by an F420H2-dependent reductase. Angewandte Chemie (International Ed. in English). PMID 32648341 DOI: 10.1002/Anie.202008035  0.351
2020 Yang W, Kong L, Wang Q, Deng Z, You D. Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in . Synthetic and Systems Biotechnology. 5: 121-130. PMID 32637665 DOI: 10.1016/J.Synbio.2020.06.001  0.357
2020 Tong Y, Deng Z. An aurora of natural products-based drug discovery is coming. Synthetic and Systems Biotechnology. 5: 92-96. PMID 32537523 DOI: 10.1016/J.Synbio.2020.05.003  0.303
2020 Wu X, Cao B, Aquino P, Chiu TP, Chen C, Jiang S, Deng Z, Chen S, Rohs R, Wang L, Galagan JE, Dedon PC. Epigenetic competition reveals density-dependent regulation and target site plasticity of phosphorothioate epigenetics in bacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 32518115 DOI: 10.1073/Pnas.2002933117  0.314
2020 Liu L, Jiang S, Xing M, Chen C, Lai C, Li N, Liu G, Wu D, Gao H, Hong L, Tan P, Chen S, Deng Z, Wu G, Wang L. Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System. Mbio. 11. PMID 32345643 DOI: 10.1128/Mbio.00488-20  0.339
2020 Li S, Liu Q, Zhong Z, Deng Z, Sun Y. Exploration of Hygromycin B Biosynthesis Utilizing CRISPR-Cas9-Associated Base Editing. Acs Chemical Biology. PMID 32275383 DOI: 10.1021/Acschembio.0C00071  0.369
2020 Zhao Q, Luo Y, Zhang X, Kang Q, Zhang D, Zhang L, Bai L, Deng Z. A severe leakage of intermediates to shunt products in acarbose biosynthesis. Nature Communications. 11: 1468. PMID 32193369 DOI: 10.1038/S41467-020-15234-8  0.341
2020 Yang L, Zhu J, Sun C, Deng Z, Qu X. Biosynthesis of plant tetrahydroisoquinoline alkaloids through an imine reductase route. Chemical Science. 11: 364-371. PMID 32190259 DOI: 10.1039/C9Sc03773J  0.317
2020 Siemon T, Wang Z, Bian G, Seitz T, Ye Z, Lu Y, Cheng S, Ding Y, Huang Y, Deng Z, Liu T, Christmann M. Semisynthesis of Plant-Derived Englerin A Enabled by Microbe Engineering of Guaia-6,10(14)-diene as Building Block. Journal of the American Chemical Society. PMID 31999448 DOI: 10.1021/Jacs.9B12940  0.315
2020 Sheng Y, Ou Y, Hu X, Deng Z, Bai L, Kang Q. Generation of tetramycin B derivative with improved pharmacological property based on pathway engineering. Applied Microbiology and Biotechnology. PMID 31989221 DOI: 10.1007/S00253-020-10391-8  0.375
2020 Song H, Rao C, Deng Z, Yi Y, Naismith JH. The biosynthetic pathway of the benzoxazole in nataxazole proceeds via an unstable ester and has synthetic utility. Angewandte Chemie (International Ed. in English). PMID 31903677 DOI: 10.1002/Anie.201915685  0.351
2019 Zhao Y, Tian J, Zheng G, Chen J, Sun C, Yang Z, Zimin AA, Jiang W, Deng Z, Wang Z, Lu Y. Multiplex genome editing using a dCas9-cytidine deaminase fusion in Streptomyces. Science China. Life Sciences. PMID 31872379 DOI: 10.1007/S11427-019-1559-Y  0.364
2019 Liu R, Fang F, An Z, Huang R, Wang Y, Sun X, Fu S, Fu A, Deng Z, Liu T. Genomics-driven discovery of the biosynthetic gene cluster of maduramicin and its overproduction in Actinomadura sp. J1-007. Journal of Industrial Microbiology & Biotechnology. PMID 31853778 DOI: 10.1007/S10295-019-02256-5  0.402
2019 Xiong W, Yin C, Peng W, Deng Z, Lin S, Liang R. Characterization of an 17β-estradiol-degrading bacterium Stenotrophomonas maltophilia SJTL3 tolerant to adverse environmental factors. Applied Microbiology and Biotechnology. PMID 31834439 DOI: 10.1007/S00253-019-10281-8  0.321
2019 Ma L, Sun S, Yuan Z, Deng Z, Tang Y, Yu Y. Three putative DNA replication/repair elements encoding genes confer self-resistance to distamycin in Streptomyces netropsis. Acta Biochimica Et Biophysica Sinica. PMID 31833535 DOI: 10.1093/Abbs/Gmz133  0.381
2019 Liu X, Hua K, Liu D, Wu ZL, Wang Y, Zhang H, Deng Z, Pfeifer BA, Jiang M. Heterologous Biosynthesis of Type II Polyketide Products Using E. coli. Acs Chemical Biology. PMID 31825590 DOI: 10.1021/Acschembio.9B00827  0.356
2019 Kong L, Liu J, Zheng X, Deng Z, You D. CtcS, a MarR family regulator, regulates chlortetracycline biosynthesis. Bmc Microbiology. 19: 279. PMID 31823730 DOI: 10.1186/S12866-019-1670-9  0.323
2019 Kong L, Xu G, Liu X, Wang J, Tang Z, Cai YS, Shen K, Tao W, Zheng Y, Deng Z, Price NPJ, Chen W. Divergent Biosynthesis of C-Nucleoside Minimycin and Indigoidine in Bacteria. Iscience. 22: 430-440. PMID 31816530 DOI: 10.1016/J.Isci.2019.11.037  0.367
2019 Zhang F, Ji H, Ali I, Deng Z, Bai L, Zheng J. Structural and Biochemical insights to the Recruitment of Acyl Carrier Protein-linked Extender Units in Ansamitocin Biosynthesis. Chembiochem : a European Journal of Chemical Biology. PMID 31777147 DOI: 10.1002/Cbic.201900628  0.314
2019 Pu T, Mei Z, Zhang W, Liang WJ, Zhou X, Liang J, Deng Z, Wang Z. An in vitro DNA Phosphorothioate Modification Reaction. Molecular Microbiology. PMID 31749226 DOI: 10.1111/Mmi.14430  0.302
2019 Liu Y, Su L, Fang Q, Tabudravu J, Yang X, Rickaby K, Trembleau L, Kyeremeh K, Deng Z, Deng H, Yu Y. Enzymatic reconstitution and biosynthetic investigation of the bacterial carbazole neocarazostatin A. The Journal of Organic Chemistry. PMID 31729221 DOI: 10.1021/Acs.Joc.9B02688  0.356
2019 Chang Y, Chai B, Ding Y, He M, Zheng L, Teng Y, Deng Z, Yu Y, Liu T. Overproduction of gentamicin B in industrial strain CCTCC M 2018898 by cloning of the missing genes and . Metabolic Engineering Communications. 9: e00096. PMID 31720212 DOI: 10.1016/J.Mec.2019.E00096  0.356
2019 Long Q, Jeffries DE, Lin S, Chen X, He W, Wang Y, Deng Z, Lindsley CW, Tao M. RedH and PigC Catalyze the Biosynthesis of Hybrubins via Phosphorylation of 4'-Methoxy-2,2'-Bipyrrole-5'-Carbaldehyde. Applied and Environmental Microbiology. PMID 31704680 DOI: 10.1128/Aem.02331-19  0.315
2019 Zhang M, Zhang P, Xu G, Zhou W, Gao Y, Gong R, Cai YS, Cong H, Deng Z, Price NPJ, Mao X, Chen W. Comparative investigation into formycin A and pyrazofurin A biosynthesis reveals branch pathways for the construction of -nucleoside scaffolds. Applied and Environmental Microbiology. PMID 31676476 DOI: 10.1128/Aem.01971-19  0.4
2019 Kang W, Ma T, Liu M, Qu J, Liu Z, Zhang H, Shi B, Fu S, Ma J, Lai LTF, He S, Qu J, Wing-Ngor Au S, Ho Kang B, Yu Lau WC, ... Deng Z, et al. Modular enzyme assembly for enhanced cascade biocatalysis and metabolic flux. Nature Communications. 10: 4248. PMID 31534134 DOI: 10.1038/S41467-019-12247-W  0.341
2019 Shi B, Ma T, Ye Z, Li X, Huang Y, Zhou Z, Ding Y, Deng Z, Liu T. Systematic metabolic engineering of Saccharomyces cerevisiae for lycopene overproduction. Journal of Agricultural and Food Chemistry. PMID 31532654 DOI: 10.1021/Acs.Jafc.9B04519  0.358
2019 Liu Q, Fan W, Zhao Y, Deng Z, Feng Y. Probing and Engineering the Fatty Acyl Substrate Selectivity of Starter Condensation Domains of Nonribosomal Peptide Synthetases in Lipopeptide Biosynthesis. Biotechnology Journal. e1900175. PMID 31520458 DOI: 10.1002/Biot.201900175  0.322
2019 Yuan W, Lv S, Chen L, Zhao Y, Deng Z, Hong K. Production of sesterterpene ophiobolin by a bifunctional terpene synthase in Escherichia coli. Applied Microbiology and Biotechnology. PMID 31515597 DOI: 10.1007/S00253-019-10103-X  0.393
2019 Sun X, Cai YS, Yuan Y, Bian G, Ye Z, Deng Z, Liu T. Genome mining in J1-030: discovery and identification of novel sesquiterpene synthase and its products. Beilstein Journal of Organic Chemistry. 15: 2052-2058. PMID 31501673 DOI: 10.3762/Bjoc.15.202  0.334
2019 Deng Q, Liu Y, Chen L, Xu M, Naowarojna N, Lee N, Chen L, Zhu D, Hong X, Deng Z, Liu P, Zhao C. Biochemical Characterization of a Multifunctional Mononuclear Nonheme Iron Enzyme (PtlD) in Neopentalenoketolactone Biosynthesis. Organic Letters. PMID 31490082 DOI: 10.1021/Acs.Orglett.9B02872  0.415
2019 Tao W, Chen L, Zhao C, Wu J, Yan D, Deng Z, Sun Y. In vitro Packaging Mediated One-Step Targeted Cloning of Natural Product Pathway. Acs Synthetic Biology. PMID 31487454 DOI: 10.1021/Acssynbio.9B00248  0.421
2019 Qian H, Yu H, Li P, Zhu E, Yao Q, Tai C, Deng Z, Gerdes K, He X, Gan J, Ou HY. Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex. Nucleic Acids Research. PMID 31260525 DOI: 10.1093/Nar/Gkz563  0.317
2019 Zhang F, Shi T, Ji H, Ali I, Huang S, Deng Z, Min Q, Bai L, Zhao YL, Zheng J. Structural Insights into Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase. Biochemistry. PMID 31199122 DOI: 10.1021/acs.biochem.9b00305  0.321
2019 Hu H, Wang L, Wang W, Wu G, Tao F, Xu P, Deng Z, Tang H. Regulatory Mechanism of Nicotine Degradation in . Mbio. 10. PMID 31164460 DOI: 10.1128/Mbio.00602-19  0.304
2019 Zhang W, Zhou L, Li C, Deng Z, Qu X. Rational engineering acyltransferase domain of modular polyketide synthase for expanding substrate specificity. Methods in Enzymology. 622: 271-292. PMID 31155056 DOI: 10.1016/Bs.Mie.2019.02.016  0.302
2019 Mo J, Wang S, Zhang W, Li C, Deng Z, Zhang L, Qu X. Efficient editing DNA regions with high sequence identity in actinomycetal genomes by a CRISPR-Cas9 system. Synthetic and Systems Biotechnology. 4: 86-91. PMID 30891508 DOI: 10.1016/J.Synbio.2019.02.004  0.395
2019 Qiao Y, Yan J, Jia J, Xue J, Qu X, Hu Y, Deng Z, Bi H, Zhu D. Characterization of the Biosynthetic Gene Cluster for the Antibiotic Armeniaspirols in Streptomyces armeniacus. Journal of Natural Products. PMID 30747534 DOI: 10.1021/Acs.Jnatprod.8B00753  0.356
2019 Pu T, Liang J, Mei Z, Yang Y, Wang J, Zhang W, Liang WJ, Zhou X, Deng Z, Wang Z. Phosphorothioated DNA is shielded from oxidative damage. Applied and Environmental Microbiology. PMID 30737351 DOI: 10.1128/Aem.00104-19  0.326
2019 Xu Z, Li Y, Wang Y, Deng Z, Tao M. Genome-wide Mutagenesis Links Multiple Metabolic Pathways with Actinorhodin Production in . Applied and Environmental Microbiology. PMID 30709825 DOI: 10.1128/Aem.03005-18  0.41
2019 Shen J, Kong L, Li Y, Zheng X, Wang Q, Yang W, Deng Z, You D. A LuxR family transcriptional regulator AniF promotes the production of anisomycin and its derivatives in var. beijingensis. Synthetic and Systems Biotechnology. 4: 40-48. PMID 30656223 DOI: 10.1016/J.Synbio.2018.12.004  0.393
2019 Deng Q, Xiao L, Liu Y, Zhang L, Deng Z, Zhao C. industrial strain as cell factory for Ivermectin B1a production. Synthetic and Systems Biotechnology. 4: 34-39. PMID 30623120 DOI: 10.1016/J.Synbio.2018.12.003  0.375
2019 Chi H, Wang X, Shao Y, Qin Y, Deng Z, Wang L, Chen S. Engineering and modification of microbial chassis for systems and synthetic biology. Synthetic and Systems Biotechnology. 4: 25-33. PMID 30560208 DOI: 10.1016/J.Synbio.2018.12.001  0.304
2019 Li Y, Kong L, Shen J, Wang Q, Liu Q, Yang W, Deng Z, You D. Characterization of the positive SARP family regulator PieR for improving piericidin A1 production in var. Hangzhouwanensis. Synthetic and Systems Biotechnology. 4: 16-24. PMID 30560207 DOI: 10.1016/J.Synbio.2018.12.002  0.317
2019 Chen L, Naowarojna N, Chen B, Xu M, Quill M, Wang J, Deng Z, Zhao C, Liu P. Mechanistic Studies of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis Using a Tyrosine Analogue, 2-Amino-3-(4-hydroxy-3-(methoxyl) phenyl) Propanoic Acid (MeOTyr) Acs Catalysis. 9: 253-258. DOI: 10.1021/Acscatal.8B03903  0.349
2018 Peng Q, Gao G, Lü J, Long Q, Chen X, Zhang F, Xu M, Liu K, Wang Y, Deng Z, Li Z, Tao M. Engineered Strains for Optimal Identification and Expression of Cryptic Biosynthetic Gene Clusters. Frontiers in Microbiology. 9: 3042. PMID 30619133 DOI: 10.3389/Fmicb.2018.03042  0.382
2018 Xia S, Chen J, Liu L, Wei Y, Deng Z, Wang L, Chen S. Tight control of genomic phosphorothioate modification by the ATP-modulated autoregulation and reusability of DndB. Molecular Microbiology. PMID 30552823 DOI: 10.1111/Mmi.14186  0.301
2018 Yu S, Zheng C, Zhou F, Baillie DL, Rose AM, Deng Z, Chu JS. Genomic identification and functional analysis of essential genes in Caenorhabditis elegans. Bmc Genomics. 19: 871. PMID 30514206 DOI: 10.1186/S12864-018-5251-3  0.334
2018 Yuan Y, Litzenburger M, Cheng S, Bian G, Hu B, Yan P, Cai Y, Deng Z, Bernhardt R, Liu T. Sesquiterpenoids Produced by the Combination of Two Sesquiterpene Cyclases with Promiscuous Myxobacterial CYP260B1. Chembiochem : a European Journal of Chemical Biology. PMID 30484946 DOI: 10.1002/Cbic.201800670  0.308
2018 Wang X, Kong D, Huang T, Deng Z, Lin S. StnK2 catalysing a Pictet-Spengler reaction involved in the biosynthesis of the antitumor reagent streptonigrin. Organic & Biomolecular Chemistry. PMID 30483694 DOI: 10.1039/C8Ob02710B  0.32
2018 Ma T, Shi B, Ye Z, Li X, Liu M, Chen Y, Xia J, Nielsen J, Deng Z, Liu T. Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene. Metabolic Engineering. PMID 30471360 DOI: 10.1016/J.Ymben.2018.11.009  0.341
2018 Wang L, Jiang S, Deng Z, Dedon PC, Chen S. DNA phosphorothioate modification - a new multi-functional epigenetic system in bacteria. Fems Microbiology Reviews. PMID 30289455 DOI: 10.1093/Femsre/Fuy036  0.311
2018 Kamjam M, Nopnakorn P, Zhang L, Peng F, Deng Z, Hong K. Streptomyces polaris sp. nov. and Streptomyces septentrionalis sp. nov., isolated from frozen soil. Antonie Van Leeuwenhoek. PMID 30251113 DOI: 10.1007/S10482-018-1166-X  0.311
2018 Xu G, Kong L, Gong R, Xu L, Gao Y, Jiang M, Cai YS, Hong K, Hu Y, Liu P, Deng Z, Price NPJ, Chen W. Coordinated biosynthesis of the purine nucleoside antibiotics aristeromycin and coformycin in the actinomycetes. Applied and Environmental Microbiology. PMID 30217843 DOI: 10.1128/Aem.01860-18  0.388
2018 Huang T, Duan Y, Zou Y, Deng Z, Lin S. NRPS Protein MarQ Catalyzes Flexible Adenylation and Specific S-Methylation. Acs Chemical Biology. PMID 30160473 DOI: 10.1021/Acschembio.8B00364  0.349
2018 Tao W, Yang A, Deng Z, Sun Y. CRISPR/Cas9-Based Editing of for Discovery, Characterization, and Production of Natural Products. Frontiers in Microbiology. 9: 1660. PMID 30087666 DOI: 10.3389/Fmicb.2018.01660  0.366
2018 Zhang J, Li X, Deng Z, Ou HY. Comparative Analysis of CRISPR Loci Found in Streptomyces Genome Sequences. Interdisciplinary Sciences, Computational Life Sciences. PMID 30030786 DOI: 10.1007/S12539-018-0301-8  0.32
2018 Duan Y, Liu Y, Huang T, Zou Y, Huang T, Hu K, Deng Z, Lin S. Divergent biosynthesis of indole alkaloids FR900452 and spiro-maremycins. Organic & Biomolecular Chemistry. PMID 30020298 DOI: 10.1039/C8Ob01181H  0.367
2018 Yan X, Zhang B, Tian W, Dai Q, Zheng X, Hu K, Liu X, Deng Z, Qu X. Puromycin A, B and C, cryptic nucleosides identified from NRRL B-1832 by PPtase-based activation. Synthetic and Systems Biotechnology. 3: 76-80. PMID 29911201 DOI: 10.1016/J.Synbio.2018.02.001  0.341
2018 Tao H, Zhang Y, Deng Z, Liu T. Strategies for Enhancing the Yield of the Potent Insecticide Spinosad in Actinomycetes. Biotechnology Journal. e1700769. PMID 29897659 DOI: 10.1002/Biot.201700769  0.375
2018 Li S, Zhang J, Liu Y, Sun G, Deng Z, Sun Y. Direct Genetic and Enzymatic Evidence for Oxidative Cyclization in Hygromycin B Biosynthesis. Acs Chemical Biology. PMID 29878752 DOI: 10.1021/Acschembio.8B00375  0.335
2018 Liu L, Zhang Y, Jiang D, Du S, Deng Z, Wang L, Chen S. Recent advances in the genomic profiling of bacterial epigenetic modifications. Biotechnology Journal. e1800001. PMID 29878585 DOI: 10.1002/Biot.201800001  0.31
2018 Zhao Y, Zheng G, Jiang W, Deng Z, Wang Z, Lu Y. CRISPR/dCas9-mediated multiplex gene repression in Streptomyces. Biotechnology Journal. e1800121. PMID 29862648 DOI: 10.1002/Biot.201800121  0.385
2018 Liu R, Deng Z, Liu T. Streptomyces species: Ideal chassis for natural product discovery and overproduction. Metabolic Engineering. PMID 29852270 DOI: 10.1016/J.Ymben.2018.05.015  0.306
2018 Li X, Xie Y, Liu M, Tai C, Sun J, Deng Z, Ou HY. oriTfinder: a web-based tool for the identification of origin of transfers in DNA sequences of bacterial mobile genetic elements. Nucleic Acids Research. PMID 29733379 DOI: 10.1093/Nar/Gky352  0.362
2018 Wu S, Wang L, Gan R, Tong T, Bian H, Li Z, Du S, Deng Z, Chen S. Signature Arsenic Detoxification Pathways in sp. Strain GFAJ-1. Mbio. 9. PMID 29717010 DOI: 10.1128/Mbio.00515-18  0.323
2018 Gong R, Qi J, Wu P, Cai YS, Ma H, Liu Y, Duan H, Wang M, Deng Z, Price NPJ, Chen W. An ATP-dependent ligase with substrate flexibility involved in assembly of the peptidyl nucleoside antibiotic polyoxin. Applied and Environmental Microbiology. PMID 29703734 DOI: 10.1128/Aem.00501-18  0.347
2018 Qiao Y, Tong T, Xue J, Lin W, Deng Z, Cheng YQ, Zhu D. Mechanistic studies of DepR in regulating FK228 biosynthesis in Chromobacterium violaceum no. 968. Plos One. 13: e0196173. PMID 29672625 DOI: 10.1371/Journal.Pone.0196173  0.376
2018 Chen X, Xu M, Lü J, Xu J, Wang Y, Lin S, Deng Z, Tao M. Biosynthesis of Tropolones in spp: Interweaving Biosynthesis and Degradation of Phenylacetic Acid and Hydroxylations on Tropone Ring. Applied and Environmental Microbiology. PMID 29654178 DOI: 10.1128/Aem.00349-18  0.423
2018 Wu H, Liang J, Gou L, Wu Q, Liang WJ, Zhou X, Bruce IJ, Deng Z, Wang Z. Recycling of over-activated acyls by a Type II Thioesterase during Calcimycin biosynthesis in NRRL 3882. Applied and Environmental Microbiology. PMID 29654175 DOI: 10.1128/Aem.00587-18  0.396
2018 Wu H, Liang J, Wang J, Liang WJ, Gou L, Wu Q, Zhou X, Bruce IJ, Deng Z, Wang Z. Cezomycin is activated by CalC to its ester form for further biosynthesis steps in the production of calcimycin in NRRL 3882. Applied and Environmental Microbiology. PMID 29654174 DOI: 10.1128/Aem.00586-18  0.39
2018 Liu C, Yuan M, Xu X, Wang L, Keatinge-Clay AT, Deng Z, Lin S, Zheng J. Substrate-bound Structures of a Ketoreductase from Amphotericin Modular Polyketide Synthase. Journal of Structural Biology. PMID 29626512 DOI: 10.1016/J.Jsb.2018.04.001  0.306
2018 Chen L, Naowarojna N, Song H, Wang S, Wang J, Deng Z, Zhao C, Liu P. Use of a tyrosine analog to modulate the two activities of a non-heme iron enzyme OvoA in ovothiol biosynthesis, cysteine oxidation versus oxidative C-S bond formation. Journal of the American Chemical Society. PMID 29544051 DOI: 10.1021/Jacs.7B13628  0.365
2018 Tong T, Chen S, Wang L, Tang Y, Ryu JY, Jiang S, Wu X, Chen C, Luo J, Deng Z, Li Z, Lee SY, Chen S. Occurrence, evolution, and functions of DNA phosphorothioate epigenetics in bacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531068 DOI: 10.1073/Pnas.1721916115  0.302
2018 Bian G, Hou A, Yuan Y, Hu B, Cheng S, Ye Z, Di Y, Deng Z, Liu T. Metabolic Engineering-Based Rapid Characterization of a Sesquiterpene Cyclase and the Skeletons of Fusariumdiene and Fusagramineol from Fusarium graminearum. Organic Letters. PMID 29513542 DOI: 10.1021/Acs.Orglett.8B00366  0.307
2018 Choi SS, Katsuyama Y, Bai L, Deng Z, Ohnishi Y, Kim ES. Genome engineering for microbial natural product discovery. Current Opinion in Microbiology. 45: 53-60. PMID 29510374 DOI: 10.1016/J.Mib.2018.02.007  0.344
2018 Qian H, Yao Q, Tai C, Deng Z, Gan J, Ou HY. Identification and characterization of acetyltransferase-type toxin-antitoxin loci in Klebsiella pneumoniae. Molecular Microbiology. PMID 29461656 DOI: 10.1111/Mmi.13934  0.349
2018 Li S, Guo J, Reva A, Huang F, Xiong B, Liu Y, Deng Z, Leadlay PF, Sun Y. Methyltransferases of gentamicin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358400 DOI: 10.1073/Pnas.1711603115  0.37
2018 Liu X, Liu D, Xu M, Tao M, Bai L, Deng Z, Pfeifer BA, Jiang M. Reconstitution of Kinamycin Biosynthesis within the Heterologous Host Streptomyces albus J1074. Journal of Natural Products. PMID 29338229 DOI: 10.1021/Acs.Jnatprod.7B00652  0.399
2018 Zhang Y, Huang Q, Deng Z, Xu Y, Liu T. Enhancing the efficiency of cell-free protein synthesis system by systematic titration of transcription and translation components Biochemical Engineering Journal. 138: 47-53. DOI: 10.1016/J.Bej.2018.07.001  0.332
2017 Xie Y, Wei Y, Shen Y, Li X, Zhou H, Tai C, Deng Z, Ou HY. TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci. Nucleic Acids Research. PMID 29106666 DOI: 10.1093/Nar/Gkx1033  0.304
2017 Liu L, Ye M, Li X, Li J, Deng Z, Yao YF, Ou HY. Identification and Characterization of an Antibacterial Type VI Secretion System in the Carbapenem-Resistant Strain Klebsiella pneumoniae HS11286. Frontiers in Cellular and Infection Microbiology. 7: 442. PMID 29085808 DOI: 10.3389/Fcimb.2017.00442  0.353
2017 Chen S, Wang L, Jiang S, Chen C, He W, Wu X, Wang F, Tong T, Zou X, Li Z, Luo J, Deng Z. Synthetic genomes. Angewandte Chemie (International Ed. in English). PMID 29078032 DOI: 10.1002/Anie.201708741  0.309
2017 Deng Q, Zhou L, Luo M, Deng Z, Zhao C. Heterologous expression of Avermectins biosynthetic gene cluster by construction of a Bacterial Artificial Chromosome library of the producers. Synthetic and Systems Biotechnology. 2: 59-64. PMID 29062962 DOI: 10.1016/J.Synbio.2017.03.001  0.391
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2017 He N, Wu P, Lei Y, Xu B, Zhu X, Xu G, Gao Y, Qi J, Deng Z, Tang G, Chen W, Xiao Y. Construction of an octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzyme and a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics. Chemical Science. 8: 444-451. PMID 28451191 DOI: 10.1039/C6Sc01826B  0.331
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2017 Zheng X, Cheng Q, Yao F, Wang X, Kong L, Cao B, Xu M, Lin S, Deng Z, Chooi YH, You D. Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373542 DOI: 10.1073/Pnas.1701361114  0.428
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2017 Gao Y, Xu G, Wu P, Liu J, Cai YS, Deng Z, Chen W. Biosynthesis of 2' -chloropentostatin and 2' -amino-2' -deoxyadenosine highlights a single gene cluster performing two independent pathways in Actinomadura sp. ATCC 39365. Applied and Environmental Microbiology. PMID 28258148 DOI: 10.1128/Aem.00078-17  0.364
2017 Bian G, Yuan Y, Tao H, Shi X, Zhong X, Han Y, Fu S, Fang C, Deng Z, Liu T. Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6. Biotechnology Journal. PMID 28217906 DOI: 10.1002/Biot.201600697  0.349
2017 Wu T, Huang Q, Wang XL, Shi T, Bai L, Liang J, Wang Z, Deng Z, Zhao YL. Mechanistic Investigation on ROS Resistance of Phosphorothioated DNA. Scientific Reports. 7: 42823. PMID 28216673 DOI: 10.1038/Srep42823  0.3
2017 Ding W, Li Y, Zhao J, Ji X, Mo T, Qianzhu H, Tu T, Deng Z, Yu Y, Chen F, Zhang Q. The Catalytic Mechanism of the Class C radical S-Adenosylmethionine Methyltransferase NosN. Angewandte Chemie (International Ed. in English). PMID 28112859 DOI: 10.1002/Anie.201609948  0.309
2017 Wu P, Wan D, Xu G, Wang G, Ma H, Wang T, Gao Y, Qi J, Chen X, Zhu J, Li YQ, Deng Z, Chen W. An Unusual Protector-Protégé Strategy for the Biosynthesis of Purine Nucleoside Antibiotics. Cell Chemical Biology. PMID 28111097 DOI: 10.1016/J.Chembiol.2016.12.012  0.386
2017 Li J, Tai C, Deng Z, Zhong W, He Y, Ou HY. VRprofile: gene-cluster-detection-based profiling of virulence and antibiotic resistance traits encoded within genome sequences of pathogenic bacteria. Briefings in Bioinformatics. PMID 28077405 DOI: 10.1093/Bib/Bbw141  0.366
2017 Xu Z, Wang Y, Chater KF, Ou HY, Xu HH, Deng Z, Tao M. Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis. Applied and Environmental Microbiology. PMID 28062460 DOI: 10.1128/Aem.02889-16  0.423
2017 Li L, Wang H, Cheng H, Deng Z. Isomaltulose production by yeast surface display of sucrose isomerase from Pantoea dispersa on Yarrowia lipolytica Journal of Functional Foods. 32: 208-217. DOI: 10.1016/J.Jff.2017.02.036  0.32
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2016 Tao H, Zhang Y, Cao X, Deng Z, Liu T. Absolute quantification of proteins in the fatty acid biosynthetic pathway using protein standard absolute quantification. Synthetic and Systems Biotechnology. 1: 150-157. PMID 29062939 DOI: 10.1016/J.Synbio.2016.01.001  0.331
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2016 Tao W, Yurkovich ME, Wen S, Lebe KE, Samborskyy M, Liu Y, Yang A, Liu Y, Ju Y, Deng Z, Tosin M, Sun Y, Leadlay PF. A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science. 7: 376-385. PMID 28791099 DOI: 10.1039/C5Sc03059E  0.419
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2016 Chen K, Wu S, Zhu L, Zhang C, Xiang W, Deng Z, Ikeda H, Cane DE, Zhu D. Substitution of a Single Amino Acid Reverses the Regiospecificity of the Baeyer-Villiger Monooxygenase PntE in the Biosynthesis of the Antibiotic Pentalenolactone. Biochemistry. 55: 6696-6704. PMID 27933799 DOI: 10.1021/Acs.Biochem.6B01040  0.326
2016 Wang Y, Tao Z, Zheng H, Zhang F, Long Q, Deng Z, Tao M. Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy. Metabolic Engineering. PMID 27746324 DOI: 10.1016/J.Ymben.2016.10.005  0.376
2016 Su L, Lv M, Kyeremeh K, Deng Z, Deng H, Yu Y. A ThDP-dependent enzymatic carboligation reaction involved in Neocarazostatin A tricyclic carbazole formation. Organic & Biomolecular Chemistry. 14: 8679-8684. PMID 27714211 DOI: 10.1039/C6Ob01651K  0.304
2016 Zhao H, Wang L, Wan D, Qi J, Gong R, Deng Z, Chen W. Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570. Microbial Cell Factories. 15: 160. PMID 27655321 DOI: 10.1186/S12934-016-0559-7  0.394
2016 Dai D, Du A, Xiong K, Pu T, Zhou X, Deng Z, Liang J, He X, Wang Z. DNA Phosphorothioate Modification Plays a Role in Peroxides Resistance in Streptomyces lividans. Frontiers in Microbiology. 7: 1380. PMID 27630631 DOI: 10.3389/Fmicb.2016.01380  0.363
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2016 Li P, Tai C, Deng Z, Gan J, Oggioni MR, Ou HY. Identification and characterization of chromosomal relBE toxin-antitoxin locus in Streptomyces cattleya DSM46488. Scientific Reports. 6: 32047. PMID 27534445 DOI: 10.1038/Srep32047  0.336
2016 Li N, Wang H, Li L, Cheng H, Liu D, Cheng H, Deng Z. Integrated Approach To Producing High-Purity Trehalose from Maltose by the Yeast Yarrowia lipolytica Displaying Trehalose Synthase (TreS) on the Cell Surface. Journal of Agricultural and Food Chemistry. PMID 27472444 DOI: 10.1021/Acs.Jafc.6B02175  0.364
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2016 Li M, Chen L, Deng Z, Zhao C. Characterization of AmtA, an amidinotransferase involved in the biosynthesis of phaseolotoxins. Febs Open Bio. 6: 603-9. PMID 27419063 DOI: 10.1002/2211-5463.12071  0.4
2016 Chen W, Li Y, Li J, Wu L, Li Y, Wang R, Deng Z, Zhou J. An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis. Protein & Cell. PMID 27412636 DOI: 10.1007/S13238-016-0289-Y  0.32
2016 Wu S, Huang T, Xie D, Wo J, Wang X, Deng Z, Lin S. Xantholipin B produced by the stnR inactivation mutant Streptomyces flocculus CGMCC 4.1223 WJN-1. The Journal of Antibiotics. PMID 27328868 DOI: 10.1038/Ja.2016.60  0.34
2016 Ye Z, Li X, Cheng Y, Liu Z, Tan G, Zhu F, Fu S, Deng Z, Liu T. Evaluation of 3-hydroxypropionate biosynthesis in vitro by partial introduction of the 3-hydroxypropionate/4-hydroxybutyrate cycle from Metallosphaera sedula. Journal of Industrial Microbiology & Biotechnology. PMID 27300329 DOI: 10.1007/S10295-016-1793-Z  0.36
2016 Chai H, Yin R, Liu Y, Meng H, Zhou X, Zhou G, Bi X, Yang X, Zhu T, Zhu W, Deng Z, Hong K. Sesterterpene ophiobolin biosynthesis involving multiple gene clusters in Aspergillus ustus. Scientific Reports. 6: 27181. PMID 27273151 DOI: 10.1038/Srep27181  0.381
2016 Huang T, Li L, Brock N, Deng Z, Lin S. Functional Characterization of PyrG, An Unusual NRPS Module from Pyridomycin Biosynthetic Pathway. Chembiochem : a European Journal of Chemical Biology. PMID 27197800 DOI: 10.1002/Cbic.201600156  0.313
2016 Lv M, Ji X, Zhao J, Li Y, Zhang C, Su L, Ding W, Deng Z, Yu Y, Zhang Q. Characterization of a C3 deoxygenation pathway reveals a key branch point in aminoglycoside biosynthesis. Journal of the American Chemical Society. PMID 27120352 DOI: 10.1021/Jacs.6B02221  0.391
2016 An J, Zhang L, Li L, Liu D, Cheng H, Wang H, Nawaz MZ, Cheng H, Deng Z. An alternative approach to synthesizing galactooligosaccharides by cell-surface display of β-galactosidase on Yarrowia lipolytica. Journal of Agricultural and Food Chemistry. PMID 27090877 DOI: 10.1021/Acs.Jafc.5B06138  0.31
2016 Wang Y, Wang J, Yu S, Wang F, Ma H, Yue C, Liu M, Deng Z, Huang Y, Qu X. Identifying the Minimal Enzymes for Unusual Carbon-Sulfur Bonds Formation in the Thienodolin Biosynthesis. Chembiochem : a European Journal of Chemical Biology. PMID 26854280 DOI: 10.1002/Cbic.201500670  0.362
2016 Bi D, Xie Y, Tai C, Jiang X, Zhang J, Harrison EM, Jia S, Deng Z, Rajakumar K, Ou HY. A Site-Specific Integrative Plasmid Found in Pseudomonas aeruginosa Clinical Isolate HS87 along with A Plasmid Carrying an Aminoglycoside-Resistant Gene. Plos One. 11: e0148367. PMID 26841043 DOI: 10.1371/Journal.Pone.0148367  0.352
2016 Zhao Z, Shi T, Xu M, Brock NL, Zhao YL, Wang Y, Deng Z, Pang X, Tao M. Hybrubins: Bipyrrole Tetramic Acids Obtained by Crosstalk between a Truncated Undecylprodigiosin Pathway and Heterologous Tetramic Acid Biosynthetic Genes. Organic Letters. PMID 26800378 DOI: 10.1021/Acs.Orglett.5B03609  0.389
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2016 Ma T, Deng Z, Liu T. Microbial production strategies and applications of lycopene and other terpenoids. World Journal of Microbiology & Biotechnology. 32: 15. PMID 26715120 DOI: 10.1007/S11274-015-1975-2  0.326
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2016 Lan Y, Zou Y, Huang T, Wang X, Brock NL, Deng Z, Lin S. Indole methylation protects diketopiperazine configuration in the maremycin biosynthetic pathway Science China Chemistry. 59: 1224-1228. DOI: 10.1007/S11426-016-0026-7  0.357
2015 Huang S, Elsayed SS, Lv M, Tabudravu J, Rateb ME, Gyampoh R, Kyeremeh K, Ebel R, Jaspars M, Deng Z, Yu Y, Deng H. Biosynthesis of Neocarazostatin A Reveals the Sequential Carbazole Prenylation and Hydroxylation in the Tailoring Steps. Chemistry & Biology. PMID 26670080 DOI: 10.1016/J.Chembiol.2015.10.012  0.37
2015 Yu G, Li L, Liu X, Liu G, Deng Z, Zabriskie MT, Jiang M, He X. The standalone aminopeptidase PepN catalyzes the maturation of blasticidin S from leucylblasticidin S. Scientific Reports. 5: 17641. PMID 26621790 DOI: 10.1038/Srep17641  0.326
2015 Ma T, Zhou Y, Li X, Zhu F, Cheng Y, Liu Y, Deng Z, Liu T. Genome mining of astaxanthin biosynthetic genes from Sphingomonas sp. ATCC 55669 for heterologous overproduction in Escherichia coli. Biotechnology Journal. PMID 26580858 DOI: 10.1002/Biot.201400827  0.399
2015 Liu Y, Tao W, Wen S, Li Z, Yang A, Deng Z, Sun Y. In Vitro CRISPR/Cas9 System for Efficient Targeted DNA Editing. Mbio. 6. PMID 26556277 DOI: 10.1128/Mbio.01714-15  0.373
2015 Zhu C, Kang Q, Bai L, Cheng L, Deng Z. Identification and engineering of regulation-related genes toward improved kasugamycin production. Applied Microbiology and Biotechnology. PMID 26521251 DOI: 10.1007/S00253-015-7082-3  0.388
2015 Lv M, Zhao J, Deng Z, Yu Y. Characterization of the Biosynthetic Gene Cluster for Benzoxazole Antibiotics A33853 Reveals Unusual Assembly Logic. Chemistry & Biology. 22: 1313-24. PMID 26496684 DOI: 10.1016/J.Chembiol.2015.09.005  0.323
2015 Zhang L, Li L, Deng Z, Hong K. Micromonospora zhanjiangensis sp. nov., isolated from mangrove forest. International Journal of Systematic and Evolutionary Microbiology. PMID 26446196 DOI: 10.1099/Ijsem.0.000667  0.32
2015 Zeng H, Wen S, Xu W, He Z, Zhai G, Liu Y, Deng Z, Sun Y. Highly efficient editing of the actinorhodin polyketide chain length factor gene in Streptomyces coelicolor M145 using CRISPR/Cas9-CodA(sm) combined system. Applied Microbiology and Biotechnology. PMID 26318449 DOI: 10.1007/S00253-015-6931-4  0.376
2015 Chen L, Li P, Deng Z, Zhao C. Ornithine Transcarbamylase ArgK Plays a Dual role for the Self-defense of Phaseolotoxin Producing Pseudomonas syringae pv. phaseolicola. Scientific Reports. 5: 12892. PMID 26256666 DOI: 10.1038/Srep12892  0.41
2015 Bi D, Jiang X, Sheng ZK, Ngmenterebo D, Tai C, Wang M, Deng Z, Rajakumar K, Ou HY. Mapping the resistance-associated mobilome of a carbapenem-resistant Klebsiella pneumoniae strain reveals insights into factors shaping these regions and facilitates generation of a 'resistance-disarmed' model organism. The Journal of Antimicrobial Chemotherapy. 70: 2770-4. PMID 26169555 DOI: 10.1093/Jac/Dkv204  0.315
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2015 Tao H, Guo D, Zhang Y, Deng Z, Liu T. Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property. Biotechnology For Biofuels. 8: 92. PMID 26120362 DOI: 10.1186/S13068-015-0270-7  0.305
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2015 Li J, Yao Y, Xu HH, Hao L, Deng Z, Rajakumar K, Ou HY. SecReT6: a web-based resource for type VI secretion systems found in bacteria. Environmental Microbiology. 17: 2196-202. PMID 25640659 DOI: 10.1111/1462-2920.12794  0.325
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2014 Zhao C, Qi J, Tao W, He L, Xu W, Chan J, Deng Z. Characterization of biosynthetic genes of ascamycin/dealanylascamycin featuring a 5'-O-sulfonamide moiety in Streptomyces sp. JCM9888. Plos One. 9: e114722. PMID 25479601 DOI: 10.1371/Journal.Pone.0114722  0.371
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2013 Xu D, Liu G, Cheng L, Lu X, Chen W, Deng Z. Identification of Mur34 as the novel negative regulator responsible for the biosynthesis of muraymycin in Streptomyces sp. NRRL30471. Plos One. 8: e76068. PMID 24143177 DOI: 10.1371/Journal.Pone.0076068  0.391
2013 Feng J, Wu J, Dai N, Lin S, Xu HH, Deng Z, He X. Discovery and characterization of BlsE, a radical S-adenosyl-L-methionine decarboxylase involved in the blasticidin S biosynthetic pathway. Plos One. 8: e68545. PMID 23874663 DOI: 10.1371/Journal.Pone.0068545  0.339
2013 Pan W, Kang Q, Wang L, Bai L, Deng Z. Asm8, a specific LAL-type activator of 3-amino-5-hydroxybenzoate biosynthesis in ansamitocin production Science China-Life Sciences. 56: 601-608. PMID 23832249 DOI: 10.1007/S11427-013-4502-4  0.437
2013 Zhu T, Cheng X, Liu Y, Deng Z, You D. Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens. Metabolic Engineering. 19: 69-78. PMID 23800859 DOI: 10.1016/J.Ymben.2013.06.003  0.35
2013 Gou L, Wu Q, Lin S, Li X, Liang J, Zhou X, An D, Deng Z, Wang Z. Mutasynthesis of pyrrole spiroketal compound using calcimycin 3-hydroxy anthranilic acid biosynthetic mutant. Applied Microbiology and Biotechnology. 97: 8183-91. PMID 23666477 DOI: 10.1007/S00253-013-4882-1  0.343
2013 Wu Q, Gou L, Lin S, Liang J, Yin J, Zhou X, Bai L, An D, Deng Z, Wang Z. Characterization of the N-methyltransferase CalM involved in calcimycin biosynthesis by Streptomyces chartreusis NRRL 3882. Biochimie. 95: 1487-93. PMID 23583975 DOI: 10.1016/J.Biochi.2013.03.014  0.391
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2013 Zou Y, Yin H, Kong D, Deng Z, Lin S. A trans-acting ketoreductase in biosynthesis of a symmetric polyketide dimer SIA7248. Chembiochem : a European Journal of Chemical Biology. 14: 679-83. PMID 23505159 DOI: 10.1002/Cbic.201300068  0.353
2013 Zhang C, Kong L, Liu Q, Lei X, Zhu T, Yin J, Lin B, Deng Z, You D. In vitro characterization of echinomycin biosynthesis: formation and hydroxylation of L-tryptophanyl-S-enzyme and oxidation of (2S,3S) β-hydroxytryptophan. Plos One. 8: e56772. PMID 23437232 DOI: 10.1371/Journal.Pone.0056772  0.34
2013 Li L, Wu J, Deng Z, Zabriskie TM, He X. Streptomyces lividans blasticidin S deaminase and its application in engineering a blasticidin S-producing strain for ease of genetic manipulation. Applied and Environmental Microbiology. 79: 2349-57. PMID 23377931 DOI: 10.1128/Aem.03254-12  0.324
2013 Lei X, Kong L, Zhang C, Liu Q, Yao F, Zhang W, Deng Z, You D. In vivo investigation of the substrate recognition capability and activity affecting amino acid residues of glycosyltransferase FscMI in the biosynthesis of candicidin. Molecular Biosystems. 9: 422-30. PMID 23324745 DOI: 10.1039/C2Mb25464F  0.4
2013 Zhu D, Wang Y, Zhang M, Ikeda H, Deng Z, Cane DE. Product-mediated regulation of pentalenolactone biosynthesis in Streptomyces species by the MarR/SlyA family activators PenR and PntR. Journal of Bacteriology. 195: 1255-66. PMID 23316039 DOI: 10.1128/Jb.02079-12  0.397
2013 Xu F, Kong D, He X, Zhang Z, Han M, Xie X, Wang P, Cheng H, Tao M, Zhang L, Deng Z, Lin S. Characterization of Streptonigrin Biosynthesis Reveals a Cryptic Carboxyl Methylation and an Unusual Oxidative Cleavage of a N–C Bond Journal of the American Chemical Society. 135: 1739-1748. PMID 23301954 DOI: 10.1021/Ja3069243  0.396
2013 Bi D, Liu L, Tai C, Deng Z, Rajakumar K, Ou H. SecReT4: a web-based bacterial type IV secretion system resource Nucleic Acids Research. 41: 660-665. PMID 23193298 DOI: 10.1093/Nar/Gks1248  0.338
2013 Ren J, Li L, Wei B, Tang YL, Deng ZX, Sun M, Hong K. Micromonospora wenchangensis sp. nov., isolated from mangrove soil. International Journal of Systematic and Evolutionary Microbiology. 63: 2389-95. PMID 23178730 DOI: 10.1099/Ijs.0.045476-0  0.31
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2013 Tang YL, Lin HP, Xie QY, Li L, Peng F, Deng Z, Hong K. Actinoallomurus acanthiterrae sp. nov., an actinomycete isolated from rhizosphere soil of the mangrove plant Acanthus ilicifolius. International Journal of Systematic and Evolutionary Microbiology. 63: 1874-9. PMID 23002049 DOI: 10.1099/Ijs.0.043380-0  0.304
2013 Tao W, Zhu M, Deng Z, Sun Y. Biosynthesis of tetronate antibiotics: A growing family of natural products with broad biological activities Science China-Chemistry. 56: 1364-1371. DOI: 10.1007/S11426-013-4921-X  0.376
2012 An X, Xiong W, Yang Y, Li F, Zhou X, Wang Z, Deng Z, Liang J. A novel target of IscS in Escherichia coli: participating in DNA phosphorothioation. Plos One. 7: e51265. PMID 23240007 DOI: 10.1371/Journal.Pone.0051265  0.368
2012 Li J, Qu X, He X, Duan L, Wu G, Bi D, Deng Z, Liu W, Ou HY. ThioFinder: A Web-Based Tool for the Identification of Thiopeptide Gene Clusters in DNA Sequences Plos One. 7. PMID 23029291 DOI: 10.1371/Journal.Pone.0045878  0.393
2012 Cao B, Yao F, Zheng X, Cui D, Shao Y, Zhu C, Deng Z, You D. Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment. Chembiochem. 13: 2234-2242. PMID 22961947 DOI: 10.1002/Cbic.201200402  0.414
2012 Zhao C, Li P, Deng Z, Ou HY, McGlinchey RP, O'Hagan D. Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants. Bioorganic Chemistry. 44: 1-7. PMID 22858315 DOI: 10.1016/J.Bioorg.2012.06.002  0.398
2012 Wu H, Qu S, Lu C, Zheng H, Zhou X, Bai L, Deng Z. Genomic and transcriptomic insights into the thermo-regulated biosynthesis of validamycin in Streptomyces hygroscopicus 5008. Bmc Genomics. 13: 337. PMID 22827618 DOI: 10.1186/1471-2164-13-337  0.318
2012 Wu J, Li L, Deng Z, Zabriskie TM, He X. Analysis of the mildiomycin biosynthesis gene cluster in Streptoverticillum remofaciens ZJU5119 and characterization of MilC, a hydroxymethyl cytosyl-glucuronic acid synthase. Chembiochem : a European Journal of Chemical Biology. 13: 1613-21. PMID 22753012 DOI: 10.1002/Cbic.201200173  0.382
2012 Chen F, Zhang Z, Lin K, Qian T, Zhang Y, You D, He X, Wang Z, Liang J, Deng Z, Wu G. Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation. Plos One. 7: e36635. PMID 22570733 DOI: 10.1371/Journal.Pone.0036635  0.334
2012 Hu W, Wang C, Liang J, Zhang T, Hu Z, Wang Z, Lan W, Li F, Wu H, Ding J, Wu G, Deng Z, Cao C. Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification. Cell Research. 22: 1203-6. PMID 22525332 DOI: 10.1038/Cr.2012.66  0.301
2012 Chen L, Wang Y, Guo H, Xu M, Deng Z, Tao M. High-throughput screening for Streptomyces antibiotic biosynthesis activators. Applied and Environmental Microbiology. 78: 4526-8. PMID 22504805 DOI: 10.1128/Aem.00348-12  0.395
2012 Wei ZH, Wu H, Bai L, Deng Z, Zhong JJ. Temperature shift-induced reactive oxygen species enhanced validamycin A production in fermentation of Streptomyces hygroscopicus 5008. Bioprocess and Biosystems Engineering. 35: 1309-16. PMID 22481376 DOI: 10.1007/S00449-012-0718-0  0.307
2012 Zhai L, Lin S, Qu D, Hong X, Bai L, Chen W, Deng Z. Engineering of an industrial polyoxin producer for the rational production of hybrid peptidyl nucleoside antibiotics. Metabolic Engineering. 14: 388-93. PMID 22465029 DOI: 10.1016/J.Ymben.2012.03.006  0.336
2012 Zhang W, Wang L, Kong L, Wang T, Chu Y, Deng Z, You D. Unveiling the post-PKS redox tailoring steps in biosynthesis of the type II polyketide antitumor antibiotic xantholipin. Chemistry & Biology. 19: 422-32. PMID 22444597 DOI: 10.1016/J.Chembiol.2012.01.016  0.402
2012 Liu P, Li P, Jiang X, Bi D, Xie Y, Tai C, Deng Z, Rajakumar K, Ou HY. Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain isolated from human sputum. Journal of Bacteriology. 194: 1841-2. PMID 22408243 DOI: 10.1128/Jb.00043-12  0.31
2012 Wei ZH, Bai L, Deng Z, Zhong JJ. Impact of nitrogen concentration on validamycin A production and related gene transcription in fermentation of Streptomyces hygroscopicus 5008. Bioprocess and Biosystems Engineering. 35: 1201-8. PMID 22382443 DOI: 10.1007/S00449-012-0707-3  0.342
2012 Lee MJ, Kong D, Han K, Sherman DH, Bai L, Deng Z, Lin S, Kim ES. Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica. Applied Microbiology and Biotechnology. 95: 157-68. PMID 22382166 DOI: 10.1007/S00253-012-3955-X  0.428
2012 Liu Q, Yao F, Chooi YH, Kang Q, Xu W, Li Y, Shao Y, Shi Y, Deng Z, Tang Y, You D. Elucidation of Piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation. Chemistry & Biology. 19: 243-53. PMID 22365607 DOI: 10.1016/J.Chembiol.2011.12.018  0.343
2012 Wang T, Bai L, Zhu D, Lei X, Liu G, Deng Z, You D. Enhancing macrolide production in Streptomyces by coexpressing three heterologous genes. Enzyme and Microbial Technology. 50: 5-9. PMID 22133433 DOI: 10.1016/J.Enzmictec.2011.09.014  0.401
2012 Yu Q, Du A, Liu T, Deng Z, He X. The biosynthesis of the polyether antibiotic nanchangmycin is controlled by two pathway-specific transcriptional activators. Archives of Microbiology. 194: 415-426. PMID 22109812 DOI: 10.1007/S00203-011-0768-8  0.39
2012 Zhou H, Wang Y, Yu Y, Bai T, Chen L, Liu P, Guo H, Zhu C, Tao M, Deng Z. A non-restricting and non-methylating Escherichia coli strain for DNA cloning and high-throughput conjugation to Streptomyces coelicolor. Current Microbiology. 64: 185-90. PMID 22105763 DOI: 10.1007/S00284-011-0048-5  0.41
2012 Kang Q, Bai L, Deng Z. Toward steadfast growth of antibiotic research in China: from natural products to engineered biosynthesis. Biotechnology Advances. 30: 1228-1241. PMID 21930196 DOI: 10.1016/J.Biotechadv.2011.09.001  0.35
2011 Li Y, Zhao P, Kang Q, Ma J, Bai L, Deng Z. Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis. Chemistry & Biology. 18: 1571-80. PMID 22195559 DOI: 10.1016/J.Chembiol.2011.11.007  0.347
2011 Doroghazi JR, Ju KS, Brown DW, Labeda DP, Deng Z, Metcalf WW, Chen W, Price NP. Genome sequences of three tunicamycin-producing Streptomyces Strains, S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396. Journal of Bacteriology. 193: 7021-2. PMID 22123769 DOI: 10.1128/Jb.06262-11  0.684
2011 Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L, Deng Z. Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis. Applied Microbiology and Biotechnology. 92: 337-45. PMID 21713508 DOI: 10.1007/S00253-011-3439-4  0.371
2011 Wang P, Gao X, Chooi YH, Deng Z, Tang Y. Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus. Microbiology (Reading, England). 157: 2401-9. PMID 21622525 DOI: 10.1099/Mic.0.048439-0  0.375
2011 He YW, Wu J, Zhou L, Yang F, He YQ, Jiang BL, Bai L, Xu Y, Deng Z, Tang JL, Zhang LH. Xanthomonas campestris diffusible factor is 3-hydroxybenzoic acid and is associated with xanthomonadin biosynthesis, cell viability, antioxidant activity, and systemic invasion. Molecular Plant-Microbe Interactions : Mpmi. 24: 948-57. PMID 21539432 DOI: 10.1094/Mpmi-02-11-0031  0.307
2011 Huang T, Wang Y, Yin J, Du Y, Tao M, Xu J, Chen W, Lin S, Deng Z. Identification and characterization of the pyridomycin biosynthetic gene cluster of Streptomyces pyridomyceticus NRRL B-2517 Journal of Biological Chemistry. 286: 20648-20657. PMID 21454714 DOI: 10.1074/Jbc.M110.180000  0.39
2011 Wang L, Chen S, Vergin KL, Giovannoni SJ, Chan SW, DeMott MS, Taghizadeh K, Cordero OX, Cutler M, Timberlake S, Alm EJ, Polz MF, Pinhassi J, Deng Z, Dedon PC. DNA phosphorothioation is widespread and quantized in bacterial genomes. Proceedings of the National Academy of Sciences of the United States of America. 108: 2963-8. PMID 21285367 DOI: 10.1073/Pnas.1017261108  0.344
2011 Cheng L, Chen W, Zhai L, Xu D, Huang T, Lin S, Zhou X, Deng Z. Identification of the gene cluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471. Molecular Biosystems. 7: 920-7. PMID 21180767 DOI: 10.1039/C0Mb00237B  0.394
2011 Yang J, Xu H, Zhang Y, Bai L, Deng Z, Mahmud T. Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis. Organic & Biomolecular Chemistry. 9: 438-49. PMID 20981366 DOI: 10.1039/C0Ob00475H  0.418
2011 Lin J, Bai L, Deng Z, Zhong JJ. Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum. Bioresource Technology. 102: 1863-8. PMID 20980145 DOI: 10.1016/J.Biortech.2010.09.102  0.357
2011 Wei ZH, Bai L, Deng Z, Zhong JJ. Enhanced production of validamycin A by H2O2-induced reactive oxygen species in fermentation of Streptomyces hygroscopicus 5008. Bioresource Technology. 102: 1783-7. PMID 20952185 DOI: 10.1016/J.Biortech.2010.08.114  0.33
2011 Shao Y, Harrison EM, Bi D, Tai C, He X, Ou HY, Rajakumar K, Deng Z. TADB: a web-based resource for Type 2 toxin-antitoxin loci in bacteria and archaea. Nucleic Acids Research. 39: D606-11. PMID 20929871 DOI: 10.1093/Nar/Gkq908  0.336
2011 Yu Q, Bai L, Zhou X, Deng Z. Inactivation of the positive LuxR-type oligomycin biosynthesis regulators OlmRI and OlmRII increases avermectin production in Streptomyces avermitilis Chinese Science Bulletin. 57: 869-876. DOI: 10.1007/S11434-011-4865-5  0.392
2011 Mao X, Chen S, Shen Y, Wei D, Deng Z. Effect of copper sulfate on biosynthesis of FR-008/Candicidin complex production in Streptomyces sp. World Journal of Microbiology and Biotechnology. 27: 2033-2039. DOI: 10.1007/S11274-011-0665-Y  0.374
2010 Chen S, Wang L, Deng Z. Twenty years hunting for sulfur in DNA. Protein & Cell. 1: 14-21. PMID 21203994 DOI: 10.1007/S13238-010-0009-Y  0.322
2010 Liu G, Ou HY, Wang T, Li L, Tan H, Zhou X, Rajakumar K, Deng Z, He X. Cleavage of phosphorothioated DNA and methylated DNA by the type IV restriction endonuclease ScoMcrA. Plos Genetics. 6: e1001253. PMID 21203499 DOI: 10.1371/Journal.Pgen.1001253  0.321
2010 Zhang J, van Aartsen JJ, Jiang X, Shao Y, Tai C, He X, Tan Z, Deng Z, Jia S, Rajakumar K, Ou HY. Expansion of the known Klebsiella pneumoniae species gene pool by characterization of novel alien DNA islands integrated into tmRNA gene sites. Journal of Microbiological Methods. 84: 283-9. PMID 21182879 DOI: 10.1016/J.Mimet.2010.12.016  0.358
2010 Wu Q, Liang J, Lin S, Zhou X, Bai L, Deng Z, Wang Z. Characterization of the biosynthesis gene cluster for the pyrrole polyether antibiotic calcimycin (A23187) in Streptomyces chartreusis NRRL 3882. Antimicrobial Agents and Chemotherapy. 55: 974-82. PMID 21173184 DOI: 10.1128/Aac.01130-10  0.371
2010 Chen W, Qu D, Zhai L, Tao M, Wang Y, Lin S, Price NP, Deng Z. Characterization of the tunicamycin gene cluster unveiling unique steps involved in its biosynthesis. Protein & Cell. 1: 1093-105. PMID 21153459 DOI: 10.1007/S13238-010-0127-6  0.396
2010 Zhao C, Huang T, Chen W, Deng Z. Enhancement of the diversity of polyoxins by a thymine-7-hydroxylase homolog outside the polyoxin biosynthesis gene cluster. Applied and Environmental Microbiology. 76: 7343-7347. PMID 20817795 DOI: 10.1128/Aem.01257-10  0.328
2010 Xu T, Yao F, Zhou X, Deng Z, You D. A novel host-specific restriction system associated with DNA backbone S-modification in Salmonella. Nucleic Acids Research. 38: 7133-41. PMID 20627870 DOI: 10.1093/Nar/Gkq610  0.36
2010 He Y, Wang Z, Bai L, Liang J, Zhou X, Deng Z. Two pHZ1358-derivative vectors for efficient gene knockout in streptomyces. Journal of Microbiology and Biotechnology. 20: 678-82. PMID 20467238 DOI: 10.4014/Jmb.0910.10031  0.331
2010 Shao Y, He X, Harrison EM, Tai C, Ou HY, Rajakumar K, Deng Z. mGenomeSubtractor: a web-based tool for parallel in silico subtractive hybridization analysis of multiple bacterial genomes. Nucleic Acids Research. 38: W194-200. PMID 20435682 DOI: 10.1093/Nar/Gkq326  0.337
2010 Zhao C, Coughlin JM, Ju J, Zhu D, Wendt-Pienkowski E, Zhou X, Wang Z, Shen B, Deng Z. Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units. The Journal of Biological Chemistry. 285: 20097-108. PMID 20406823 DOI: 10.1074/Jbc.M109.090092  0.393
2010 Gai Z, Wang X, Liu X, Tai C, Tang H, He X, Wu G, Deng Z, Xu P. The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5. Plos One. 5: e10018. PMID 20368802 DOI: 10.1371/Journal.Pone.0010018  0.354
2010 He Y, Sun Y, Liu T, Zhou X, Bai L, Deng Z. Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification. Applied and Environmental Microbiology. 76: 3283-92. PMID 20348291 DOI: 10.1128/Aem.02262-09  0.386
2010 Wang J, Yu Y, Tang K, Liu W, He X, Huang X, Deng Z. Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22 Applied and Environmental Microbiology. 76: 2335-2344. PMID 20154110 DOI: 10.1128/Aem.01790-09  0.394
2010 Chen N, Ou HY, van Aartsen JJ, Jiang X, Li M, Yang Z, Wei Q, Chen X, He X, Deng Z, Rajakumar K, Lu Y. The pheV phenylalanine tRNA gene Klebsiella pneumoniae clinical isolates is an integration hotspot for possible niche-adaptation genomic islands. Current Microbiology. 60: 210-6. PMID 19921332 DOI: 10.1007/S00284-009-9526-4  0.357
2010 Cheng H, Li Z, Jiang N, Deng Z. Cloning, purification and characterization of an NAD-Dependent D-Arabitol dehydrogenase from acetic acid bacterium, Acetobacter suboxydans. The Protein Journal. 28: 263-72. PMID 19629658 DOI: 10.1007/S10930-009-9191-2  0.302
2010 Lin J, Bai L, Deng Z, Zhong J. Effect of ammonium in medium on ansamitocin P-3 production by Actinosynnema pretiosum Biotechnology and Bioprocess Engineering. 15: 119-125. DOI: 10.1007/S12257-009-3054-8  0.348
2009 Li Q, Wang X, Yin G, Gai Z, Tang H, Ma C, Deng Z, Xu P. New metabolites in dibenzofuran cometabolic degradation by a biphenyl-cultivated Pseudomonas putida strain B6-2. Environmental Science & Technology. 43: 8635-42. PMID 20028064 DOI: 10.1021/Es901991D  0.314
2009 Li R, Liu G, Xie Z, He X, Chen W, Deng Z, Tan H. PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi. Molecular Microbiology. 75: 349-64. PMID 19919670 DOI: 10.1111/J.1365-2958.2009.06968.X  0.334
2009 Xu H, Zhang Y, Yang J, Mahmud T, Bai L, Deng Z. Alternative epimerization in C(7)N-aminocyclitol biosynthesis is catalyzed by ValD, a large protein of the vicinal oxygen chelate superfamily. Chemistry & Biology. 16: 567-76. PMID 19477421 DOI: 10.1016/J.Chembiol.2009.04.006  0.316
2009 Zhang Y, Bai L, Deng Z. Functional characterization of the first two actinomycete 4-amino-4-deoxychorismate lyase genes. Microbiology. 155: 2450-2459. PMID 19389784 DOI: 10.1099/Mic.0.026336-0  0.403
2009 Li R, Xie Z, Tian Y, Yang H, Chen W, You D, Liu G, Deng Z, Tan H. polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis. Microbiology (Reading, England). 155: 1819-31. PMID 19383687 DOI: 10.1099/Mic.0.028639-0  0.403
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2009 Ou HY, He X, Shao Y, Tai C, Rajakumar K, Deng Z. dndDB: a database focused on phosphorothioation of the DNA backbone. Plos One. 4: e5132. PMID 19357771 DOI: 10.1371/Journal.Pone.0005132  0.352
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2009 Yao F, Xu T, Zhou X, Deng Z, You D. Functional analysis of spfD gene involved in DNA phosphorothioation in Pseudomonas fluorescens Pf0-1. Febs Letters. 583: 729-33. PMID 19171139 DOI: 10.1016/J.Febslet.2009.01.029  0.345
2009 Chen S, Mao X, Shen Y, Zhou Y, Li J, Wang L, Tao X, Yang L, Wang Y, Zhou X, Deng Z, Wei D. Tailoring the P450 monooxygenase gene for FR-008/candicidin biosynthesis. Applied and Environmental Microbiology. 75: 1778-81. PMID 19139241 DOI: 10.1128/Aem.00859-08  0.358
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2009 Xu H, Yang J, Bai L, Deng Z, Mahmud T. Genetically engineered production of 1,1'-bis-valienamine and validienamycin in Streptomyces hygroscopicus and their conversion to valienamine. Applied Microbiology and Biotechnology. 81: 895-902. PMID 18820907 DOI: 10.1007/S00253-008-1711-Z  0.346
2009 Li L, Bai L, Zhou X, Deng Z. Enhanced validamycin production and gene expression at elevated temperature in Streptomyces hygroscopicus subsp. jingangensis 5008 Science Bulletin. 54: 1204-1209. DOI: 10.1007/S11434-009-0128-0  0.346
2008 Shaikh F, Spence RP, Levi K, Ou H, Deng Z, Towner KJ, Rajakumar K. ATPase genes of diverse multidrug-resistant Acinetobacter baumannii isolates frequently harbour integrated DNA Journal of Antimicrobial Chemotherapy. 63: 260-264. PMID 19022777 DOI: 10.1093/Jac/Dkn481  0.349
2008 Zhou Y, Meng Q, You D, Li J, Chen S, Ding D, Zhou X, Zhou H, Bai L, Deng Z. Selective removal of aberrant extender units by a type II thioesterase for efficient FR-008/candicidin biosynthesis in Streptomyces sp. strain FR-008. Applied and Environmental Microbiology. 74: 7235-42. PMID 18836004 DOI: 10.1128/Aem.01012-08  0.396
2008 Zhao P, Bai L, Ma J, Zeng Y, Li L, Zhang Y, Lu C, Dai H, Wu Z, Li Y, Wu X, Chen G, Hao X, Shen Y, Deng Z, et al. Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins. Chemistry & Biology. 15: 863-74. PMID 18721757 DOI: 10.1016/J.Chembiol.2008.06.007  0.318
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