Rupa Sridharan, Ph.D.
Affiliations: | 2006 | University of California, Los Angeles, Los Angeles, CA |
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"Rupa Sridharan"Parents
Sign in to add mentor| Stephen Todd Smale | grad student | 2006 | UCLA (Chemistry Tree) | |
| (Analysis of the Ikaros family of proteins in thymocyte development.) | ||||
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Publications
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| Wille CK, Neumann EN, Deshpande AJ, et al. (2023) DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity. Stem Cell Reports. 18: 2451-2463 |
| Wille CK, Zhang X, Haws SA, et al. (2023) DOT1L is a barrier to histone acetylation during reprogramming to pluripotency. Science Advances. 9: eadf3980 |
| Dillingham C, Cormaty H, Morgan E, et al. (2023) KDM3A and KDM3B Maintain Naïve Pluripotency Through the Regulation of Alternative Splicing. Biorxiv : the Preprint Server For Biology |
| Zhang S, Pyne S, Pietrzak S, et al. (2023) Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets. Nature Communications. 14: 3064 |
| Lo JH, Edwards M, Langerman J, et al. (2022) Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells. Genes & Development. 36: 1079-1095 |
| Wille CK, Sridharan R. (2022) Connecting the DOTs on Cell Identity. Frontiers in Cell and Developmental Biology. 10: 906713 |
| Wille CK, Sridharan R. (2021) DOT1L inhibition enhances pluripotency beyond acquisition of epithelial identity and without immediate suppression of the somatic transcriptome. Stem Cell Reports |
| Zaidan NZ, Sridharan R. (2020) HP1γ regulates H3K36 methylation and pluripotency in embryonic stem cells. Nucleic Acids Research. 48: 12660-12674 |
| Haws SA, Yu D, Ye C, et al. (2020) Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence. Molecular Cell |
| Tran KA, Dillingham CM, Sridharan R. (2019) Coordinated removal of repressive epigenetic modifications during induced reversal of cell identity. The Embo Journal. e101681 |