Rupa Sridharan, Ph.D. - Publications

Affiliations: 
2006 University of California, Los Angeles, Los Angeles, CA 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wille CK, Neumann EN, Deshpande AJ, Sridharan R. DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity. Stem Cell Reports. 18: 2451-2463. PMID 37995701 DOI: 10.1016/j.stemcr.2023.10.017  0.351
2023 Wille CK, Zhang X, Haws SA, Denu JM, Sridharan R. DOT1L is a barrier to histone acetylation during reprogramming to pluripotency. Science Advances. 9: eadf3980. PMID 37976354 DOI: 10.1126/sciadv.adf3980  0.356
2023 Dillingham C, Cormaty H, Morgan E, Esgdaille D, Boutz P, Sridharan R. KDM3A and KDM3B Maintain Naïve Pluripotency Through the Regulation of Alternative Splicing. Biorxiv : the Preprint Server For Biology. PMID 37398291 DOI: 10.1101/2023.05.31.543088  0.366
2023 Zhang S, Pyne S, Pietrzak S, Halberg S, McCalla SG, Siahpirani AF, Sridharan R, Roy S. Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets. Nature Communications. 14: 3064. PMID 37244909 DOI: 10.1038/s41467-023-38637-9  0.33
2022 Lo JH, Edwards M, Langerman J, Sridharan R, Plath K, Smale ST. Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells. Genes & Development. 36: 1079-1095. PMID 36418052 DOI: 10.1101/gad.350113.122  0.667
2022 Wille CK, Sridharan R. Connecting the DOTs on Cell Identity. Frontiers in Cell and Developmental Biology. 10: 906713. PMID 35733849 DOI: 10.3389/fcell.2022.906713  0.411
2021 Wille CK, Sridharan R. DOT1L inhibition enhances pluripotency beyond acquisition of epithelial identity and without immediate suppression of the somatic transcriptome. Stem Cell Reports. PMID 34995500 DOI: 10.1016/j.stemcr.2021.12.004  0.363
2020 Zaidan NZ, Sridharan R. HP1γ regulates H3K36 methylation and pluripotency in embryonic stem cells. Nucleic Acids Research. 48: 12660-12674. PMID 33237287 DOI: 10.1093/nar/gkaa1091  0.427
2020 Haws SA, Yu D, Ye C, Wille CK, Nguyen LC, Krautkramer KA, Tomasiewicz JL, Yang SE, Miller BR, Liu WH, Igarashi K, Sridharan R, Tu BP, Cryns VL, Lamming DW, et al. Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence. Molecular Cell. PMID 32208170 DOI: 10.1016/J.Molcel.2020.03.004  0.318
2019 Tran KA, Dillingham CM, Sridharan R. Coordinated removal of repressive epigenetic modifications during induced reversal of cell identity. The Embo Journal. e101681. PMID 31583744 DOI: 10.15252/Embj.2019101681  0.435
2019 Tran KA, Pietrzak SJ, Zaidan NZ, Siahpirani AF, McCalla SG, Zhou AS, Iyer G, Roy S, Sridharan R. Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency. Cell Reports. 27: 1726-1741.e5. PMID 31067459 DOI: 10.1016/J.Celrep.2019.04.056  0.481
2018 Tran KA, Dillingham CM, Sridharan R. The role of α-ketoglutarate-dependent proteins in pluripotency acquisition and maintenance. The Journal of Biological Chemistry. PMID 30181211 DOI: 10.1074/Jbc.Tm118.000831  0.365
2018 Zaidan NZ, Walker KJ, Brown JE, Schaffer LV, Scalf M, Shortreed MR, Iyer G, Smith LM, Sridharan R. Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance. Stem Cell Reports. PMID 29358085 DOI: 10.1016/J.Stemcr.2017.12.016  0.435
2018 May-Simera HL, Wan Q, Jha BS, Hartford J, Khristov V, Dejene R, Chang J, Patnaik S, Lu Q, Banerjee P, Silver J, Insinna-Kettenhofen C, Patel D, Lotfi M, Malicdan M, ... ... Sridharan R, et al. Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells. Cell Reports. 22: 189-205. PMID 29298421 DOI: 10.1016/J.Celrep.2017.12.038  0.37
2017 Buxton KE, Kennedy-Darling J, Shortreed MR, Zaidan NZ, Olivier M, Scalf M, Sridharan R, Smith LM. Elucidating Protein-DNA Interactions in Human Alphoid Chromatin via Hybridization Capture and Mass Spectrometry. Journal of Proteome Research. PMID 28704058 DOI: 10.1021/Acs.Jproteome.7B00448  0.34
2017 Roy S, Sridharan R. Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes. Genome Research. PMID 28424352 DOI: 10.1101/Gr.215004.116  0.438
2016 Jackson SA, Olufs ZP, Tran KA, Zaidan NZ, Sridharan R. Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage. Stem Cell Reports. PMID 26905202 DOI: 10.1016/J.Stemcr.2016.01.009  0.409
2015 Roy S, Siahpirani AF, Chasman D, Knaack S, Ay F, Stewart R, Wilson M, Sridharan R. A predictive modeling approach for cell line-specific long-range regulatory interactions. Nucleic Acids Research. PMID 26338778 DOI: 10.1093/Nar/Gkv865  0.348
2015 Tran KA, Jackson SA, Olufs ZP, Zaidan NZ, Leng N, Kendziorski C, Roy S, Sridharan R. Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways. Nature Communications. 6: 6188. PMID 25650115 DOI: 10.1038/Ncomms7188  0.44
2013 Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA. Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1101-13. PMID 23949383 DOI: 10.4161/Epi.26025  0.321
2013 Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nature Cell Biology. 15: 872-82. PMID 23748610 DOI: 10.1038/Ncb2768  0.469
2013 Jackson SA, Sridharan R. The nexus of Tet1 and the pluripotency network. Cell Stem Cell. 12: 387-8. PMID 23561438 DOI: 10.1016/J.Stem.2013.03.007  0.345
2013 Jackson SA, Sridharan R. Peering into the Black Box of Reprogramming to the Pluripotent State Current Pathobiology Reports. 1: 129-136. DOI: 10.1007/S40139-013-0014-Y  0.399
2011 Lin JJ, Lehmann LW, Bonora G, Sridharan R, Vashisht AA, Tran N, Plath K, Wohlschlegel JA, Carey M. Mediator coordinates PIC assembly with recruitment of CHD1. Genes & Development. 25: 2198-209. PMID 21979373 DOI: 10.1101/Gad.17554711  0.496
2011 Sridharan R, Plath K. Small RNAs loom large during reprogramming. Cell Stem Cell. 8: 599-601. PMID 21624799 DOI: 10.1016/J.Stem.2011.05.009  0.329
2009 Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 460: 863-8. PMID 19587682 DOI: 10.1038/Nature08212  0.427
2009 Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. 33: 417-27. PMID 19250903 DOI: 10.1016/J.Molcel.2009.02.004  0.455
2009 Sridharan R, Tchieu J, Mason MJ, Yachechko R, Kuoy E, Horvath S, Zhou Q, Plath K. Role of the murine reprogramming factors in the induction of pluripotency. Cell. 136: 364-77. PMID 19167336 DOI: 10.1016/J.Cell.2009.01.001  0.475
2009 Plath K, Sridharan R, Tchieu J, Mason MJ, Chin M, Yachechko R, Kuoy E, Zhou Q, Lowry B. Defining the Mechanism of Transcription Factor-Induced Epigenetic Reprogramming. Blood. 114: SCI-41-SCI-41. DOI: 10.1182/Blood.V114.22.Sci-41.Sci-41  0.472
2008 Sridharan R, Plath K. Illuminating the black box of reprogramming. Cell Stem Cell. 2: 295-7. PMID 18397745 DOI: 10.1016/J.Stem.2008.03.015  0.37
2008 Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 105: 2883-8. PMID 18287077 DOI: 10.1073/Pnas.0711983105  0.381
2008 Sridharan R, Smale S. IKZF2 (IKAROS family zinc finger 2) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/15940  0.552
2007 Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 1: 55-70. PMID 18371336 DOI: 10.1016/J.Stem.2007.05.014  0.439
2007 Sridharan R, Smale ST. Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes. The Journal of Biological Chemistry. 282: 30227-38. PMID 17681952 DOI: 10.1074/Jbc.M702541200  0.582
2006 Ramirez-Carrozzi VR, Nazarian AA, Li CC, Gore SL, Sridharan R, Imbalzano AN, Smale ST. Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response. Genes & Development. 20: 282-96. PMID 16452502 DOI: 10.1101/Gad.1383206  0.591
2005 Su RC, Sridharan R, Smale ST. Assembly of silent chromatin during thymocyte development. Seminars in Immunology. 17: 129-40. PMID 15737574 DOI: 10.1016/J.Smim.2005.01.003  0.606
2003 Papathanasiou P, Perkins AC, Cobb BS, Ferrini R, Sridharan R, Hoyne GF, Nelms KA, Smale ST, Goodnow CC. Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity. 19: 131-44. PMID 12871645 DOI: 10.1016/S1074-7613(03)00168-7  0.657
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