Daniel E. Kahne
Affiliations: | 1988-2004 | Chemistry | Princeton University, Princeton, NJ |
2004- | Harvard University, Cambridge, MA, United States |
Area:
molecular mechanisms of various antibioticsWebsite:
http://www.chem.harvard.edu/groups/kahne/index.htmlGoogle:
"Daniel Kahne"Bio:
https://kahnelab.chemistry.harvard.edu/dan-kahne
https://news.harvard.edu/gazette/story/2004/11/kahne-brings-chemistry-to-life/
Mean distance: 7.2 | S | N | B | C | P |
Parents
Sign in to add mentorGilbert Stork | grad student | 1986 | Columbia | |
(Part I. Hydroxyl directed homogeneous hydrogenation using a catalytic iridium complex ; Part II. An approach to the synthesis of tetracycline) | ||||
W. Clark Still | post-doc | 1988 | Columbia |
Children
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Publications
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Park Y, Taguchi A, Baidin V, et al. (2023) A Time-Resolved FRET Assay Identifies a Small Molecule that Inhibits the Essential Bacterial Cell Wall Polymerase FtsW. Angewandte Chemie (International Ed. in English). e202301522 |
Kumar S, Mollo A, Rubino FA, et al. (2023) Chloride Ions Are Required for Thermosipho africanus MurJ Function. Mbio. e0008923 |
Kumar S, Mollo A, Kahne D, et al. (2022) The Bacterial Cell Wall: From Lipid II Flipping to Polymerization. Chemical Reviews |
Melnyk S, Stepanyshyn A, Yushchuk O, et al. (2022) Genetic approaches to improve clorobiocin production in Streptomyces roseochromogenes NRRL 3504. Applied Microbiology and Biotechnology |
Baidin V, Owens TW, Lazarus MB, et al. (2021) Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase. Journal of the American Chemical Society |
Schaefer K, Owens TW, Page JE, et al. (2020) Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization. Nature Microbiology |
Lundstedt E, Kahne D, Ruiz N. (2020) Assembly and Maintenance of Lipids at the Bacterial Outer Membrane. Chemical Reviews |
Tomasek D, Rawson S, Lee J, et al. (2020) Structure of a nascent membrane protein as it folds on the BAM complex. Nature |
Sjodt M, Rohs PDA, Gilman MSA, et al. (2020) Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nature Microbiology |
Rubino FA, Mollo A, Kumar S, et al. (2020) Detection of transport intermediates in the peptidoglycan flippase MurJ identifies residues essential for conformational cycling. Journal of the American Chemical Society |