Daniel E. Kahne

Affiliations: 
1988-2004 Chemistry Princeton University, Princeton, NJ 
 2004- Harvard University, Cambridge, MA, United States 
Area:
molecular mechanisms of various antibiotics
Website:
http://www.chem.harvard.edu/groups/kahne/index.html
Google:
"Daniel Kahne"
Bio:

https://kahnelab.chemistry.harvard.edu/dan-kahne
https://news.harvard.edu/gazette/story/2004/11/kahne-brings-chemistry-to-life/

Mean distance: 7.2
 
SNBCP

Parents

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Gilbert Stork grad student 1986 Columbia
 (Part I. Hydroxyl directed homogeneous hydrogenation using a catalytic iridium complex ; Part II. An approach to the synthesis of tetracycline)
W. Clark Still post-doc 1988 Columbia

Children

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Jeffrey Gildersleeve grad student
Michael D Mandler grad student Harvard
Ran Xie grad student
Dan Yang grad student 1991 Princeton
Amy H. Andreotti grad student 1994 Princeton
Kaustav Biswas grad student 2000 Princeton
Hayley A. Xuereb grad student 2000 Princeton
Zhong Chen grad student 2001 Princeton
Ulrike S. Eggert grad student 2001 Princeton
Kimberly M. Specht grad student 2002 Princeton
Brian V. Falcone grad student 2004 Princeton
John V. LaTour grad student 2004 Princeton
Joonwoo Nam grad student 2004 Princeton
Binyuan Sun grad student 2004 Princeton
Christopher D. Brander grad student 2005 Princeton
Catherine E. Leimkuhler grad student 2006 Harvard
Scott A. McMurry grad student 2006 Princeton
Hak S. Chung grad student 2007 Harvard
Xuechen Li grad student 2007 Harvard
Seokhee Kim grad student 2008 Harvard
Wenjiang Zhu grad student 2008 Harvard
Shu S. Chng grad student 2010 Harvard
Michael B. Lazarus grad student 2010 Harvard
Emma H. Doud grad student 2011 Harvard
Tania J. Lupoli grad student 2011 Harvard
Tsung-Shing Wang grad student 2011 Harvard
Craig Braun grad student 2012 Harvard
Elizaveta Freinkman grad student 2012 Harvard
Christine L. Hagan grad student 2012 Harvard
Yihui Wu grad student 2012 Harvard
Zhizhong Yao grad student 2012 Harvard
John Janetzko grad student 2012-2017 Harvard
Frederick A Rubino grad student 2012-2019 Harvard
Matthew J. Nava post-doc
Matthew D. Lebar post-doc 2011- Harvard
Alessio Caruso post-doc 2021- Harvard (Neurotree)
Amit Basu post-doc 1996-1999 Princeton

Collaborators

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Suzanne Walker collaborator
BETA: Related publications

Publications

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Park Y, Taguchi A, Baidin V, et al. (2023) A Time-Resolved FRET Assay Identifies a Small Molecule that Inhibits the Essential Bacterial Cell Wall Polymerase FtsW. Angewandte Chemie (International Ed. in English). e202301522
Kumar S, Mollo A, Rubino FA, et al. (2023) Chloride Ions Are Required for Thermosipho africanus MurJ Function. Mbio. e0008923
Kumar S, Mollo A, Kahne D, et al. (2022) The Bacterial Cell Wall: From Lipid II Flipping to Polymerization. Chemical Reviews
Melnyk S, Stepanyshyn A, Yushchuk O, et al. (2022) Genetic approaches to improve clorobiocin production in Streptomyces roseochromogenes NRRL 3504. Applied Microbiology and Biotechnology
Baidin V, Owens TW, Lazarus MB, et al. (2021) Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase. Journal of the American Chemical Society
Schaefer K, Owens TW, Page JE, et al. (2020) Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization. Nature Microbiology
Lundstedt E, Kahne D, Ruiz N. (2020) Assembly and Maintenance of Lipids at the Bacterial Outer Membrane. Chemical Reviews
Tomasek D, Rawson S, Lee J, et al. (2020) Structure of a nascent membrane protein as it folds on the BAM complex. Nature
Sjodt M, Rohs PDA, Gilman MSA, et al. (2020) Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nature Microbiology
Rubino FA, Mollo A, Kumar S, et al. (2020) Detection of transport intermediates in the peptidoglycan flippase MurJ identifies residues essential for conformational cycling. Journal of the American Chemical Society
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