Raymond Allen Dwek

Affiliations: 
Biochemistry University of Oxford, Oxford, United Kingdom 
Area:
Glycobiology
Website:
http://www.bioch.ox.ac.uk/aspsite/index.asp?pageid=574
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"Raymond Allen Dwek"
Bio:

http://www.a-star.edu.sg/People/OurResearchCommunity/VisitingScientists/DistinguishedVisitorProgramme/ProfRaymondDwek/tabid/733/Default.aspx

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Publications

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Robinson PC, Liew DFL, Tanner HL, et al. (2022) COVID-19 therapeutics: Challenges and directions for the future. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119893119
Dwek RA, Bell JI, Feldmann M, et al. (2022) Host-targeting oral antiviral drugs to prevent pandemics. Lancet (London, England)
Sayce AC, Martinez FO, Tyrrell BE, et al. (2021) Pathogen-induced inflammation is attenuated by the iminosugar MON-DNJ via modulation of the unfolded protein response. Immunology
Brun J, Vasiljevic S, Gangadharan B, et al. (2021) Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike. Acs Central Science. 7: 586-593
Warfield K, Alonzi DS, Hill J, et al. (2020) Targeting ER α-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections. Journal of Medicinal Chemistry
Alonzi DS, Scott KA, Dwek RA, et al. (2017) Iminosugar antivirals: the therapeutic sweet spot. Biochemical Society Transactions. 45: 571-582
Miller JL, Spiro SG, Dowall SD, et al. (2016) Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model. Plos One. 11: e0167018
Sayce AC, Alonzi DS, Killingbeck SS, et al. (2016) Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases-Not Glycolipid Processing Enzymes. Plos Neglected Tropical Diseases. 10: e0004524
Warfield KL, Plummer EM, Sayce AC, et al. (2016) Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4. Antiviral Research
Dwek RA. (2014) Journeys in science: glycobiology and other paths. Annual Review of Biochemistry. 83: 1-44
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