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Aaron L. Sarver, Ph.D. - Publications

Affiliations: 
2006 University of California, San Francisco, San Francisco, CA 
Area:
Genomic approaches to yeast molecular biology and infectious disease
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81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sarver AL, Mills LJ, Makielski KM, Temiz NA, Wang J, Spector LG, Subramanian S, Modiano JF. Distinct mechanisms of PTEN inactivation in dogs and humans highlight convergent molecular events that drive cell division in the pathogenesis of osteosarcoma. Cancer Genetics. 1-11. PMID 37267683 DOI: 10.1016/j.cancergen.2023.05.001  0.314
2021 Kim JH, Megquier K, Thomas R, Sarver AL, Song JM, Kim YT, Cheng N, Schulte AJ, Linden MA, Murugan P, Oseth L, Forster CL, Elvers I, Swofford R, Turner-Maier J, et al. Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions. Molecular Cancer Research : McR. PMID 33649193 DOI: 10.1158/1541-7786.MCR-20-0937  0.306
2020 Kim JH, Megquier K, Sarver AL, Thomas R, Schulte AJ, Wang C, Elvers I, Karlsson E, Breen M, Lindblad-Toh K, Modiano JF. Abstract 195: Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma Cancer Research. 80: 195-195. DOI: 10.1158/1538-7445.Am2020-195  0.425
2019 Langsten KL, Kim JH, Sarver AL, Dewhirst M, Modiano JF. Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment. Frontiers in Oncology. 9: 1185. PMID 31788448 DOI: 10.3389/Fonc.2019.01185  0.34
2019 Sachs K, Sarver AL, Noble-Orcutt KE, LaRue RS, Antony ML, Chang D, Lee Y, Navis CM, Hillesheim AL, Nykaza IR, Ha NA, Hansen CJ, Karadag FK, Bergerson RJ, Verneris MR, et al. Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia. Cancer Research. PMID 31784425 DOI: 10.1158/0008-5472.Can-18-2932  0.364
2019 Megquier K, Turner-Maier J, Swofford R, Kim JH, Sarver AL, Wang C, Sakthikumar S, Johnson J, Koltookian M, Lewellen M, Scott MC, Graef AJ, Borst L, Tonomura N, Alfoldi J, et al. Comparative genomics reveals shared mutational landscape in canine hemangiosarcoma and human angiosarcoma. Molecular Cancer Research : McR. PMID 31570656 DOI: 10.1158/1541-7786.Mcr-19-0221  0.364
2019 Makielski KM, Mills LJ, Sarver AL, Henson MS, Spector LG, Naik S, Modiano JF. Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review. Veterinary Sciences. 6. PMID 31130627 DOI: 10.3390/Vetsci6020048  0.318
2019 Loeb KR, Hughes BT, Fissel BM, Osteen NJ, Knoblaugh SE, Grim JE, Drury LJ, Sarver A, Dupuy AJ, Clurman BE. Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice. Scientific Reports. 9: 5488. PMID 30940846 DOI: 10.1038/S41598-019-41805-X  0.381
2019 Beckmann PJ, Larson JD, Larsson AT, Ostergaard JP, Wagner S, Rahrmann EP, Shamsan GA, Otto GM, Williams RL, Wang J, Lee C, Tschida BR, Das P, Dubuc AM, Moriarity BS, ... ... Sarver AL, et al. Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors. Cancer Research. PMID 30674530 DOI: 10.1158/0008-5472.Can-18-1261  0.386
2019 Sarver AL. Identification of Cancer Genes Based on De Novo Transposon Insertion Site Analysis Using RNA and DNA Sequencing. Methods of Molecular Biology. 1907: 73-79. PMID 30542991 DOI: 10.1007/978-1-4939-8967-6_5  0.336
2018 Sarver AL, Sarver AE, Yuan C, Subramanian S. OMCD: OncomiR Cancer Database. Bmc Cancer. 18: 1223. PMID 30522456 DOI: 10.1186/S12885-018-5085-Z  0.344
2018 Scott M, Temiz N, Sarver A, LaRue R, Rathe S, Varshney J, Wolf N, Moriarity B, Obrien T, Spector L, Largaespada D, Modiano J, Subramanian S, Sarver A. Abstract PR14: Immune cell transcript levels, metastatic progression, and survival in osteosarcoma: A comparative transcriptome analysis Omics a Journal of Integrative Biology. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr14  0.424
2018 Sarver AL, Mills L, Temiz N, Scott M, Sarver A, Spector L, Wang J, Breen M, Subramanian S, Moriarity B, Modiano J, Largaespada D. Abstract 3399: Comparative genomic analyses of osteosarcoma etiology reveal a chromosomal structural rationale for the increased incidence of osteosarcoma in dogs Cancer Research. 78: 3399-3399. DOI: 10.1158/1538-7445.Am2018-3399  0.404
2018 Camilleri ET, Beckmann PJ, Larson JD, Kurata M, Shu J, Pope E, Hudson WA, Temiz NA, Rathe SK, LaRue RS, Sarver AE, Scott MC, Varshney J, Modiano JF, Moriarity BS, ... Sarver AL, et al. Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression Cancer Research. 78: 2264-2264. DOI: 10.1158/1538-7445.Am2018-2264  0.448
2017 Kim JH, Frantz AM, Sarver AL, Gorden Klukas BH, Lewellen M, O'Brien TD, Dickerson EB, Modiano JF. Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers. Veterinary and Comparative Oncology. PMID 29152836 DOI: 10.1111/Vco.12368  0.359
2017 Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL. Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma. Cancer Research. PMID 29066513 DOI: 10.1158/0008-5472.Can-17-0576  0.418
2017 Xie C, Freeman MJ, Lu H, Wang X, Forster CL, Sarver AL, Hallstrom TC. Retinoblastoma cells activate the AKT pathway and are vulnerable to the PI3K/mTOR inhibitor NVP-BEZ235. Oncotarget. PMID 28445155 DOI: 10.18632/Oncotarget.16970  0.351
2017 Borgatti A, Koopmeiners JS, Sarver AL, Winter AL, Stuebner K, Todhunter D, Rizzardi AE, Henricksen JC, Schmechel S, Forster CL, Kim JH, Froelich J, Walz J, Henson MS, Breen M, et al. Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR. Molecular Cancer Therapeutics. PMID 28193671 DOI: 10.1158/1535-7163.Mct-16-0637  0.333
2016 Trott JF, Kim J, Aboud OA, Wettersten H, Stewart B, Berryhill G, Uzal F, Hovey RC, Chen CH, Anderson K, Graef A, Sarver AL, Modiano JF, Weiss RH. Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. Oncotarget. PMID 27572319 DOI: 10.18632/Oncotarget.11658  0.326
2016 Becker MA, Ibrahim YH, Oh AS, Fagan DH, Byron SA, Sarver AL, Lee AV, Shaw LM, Fan C, Perou CM, Yee D. Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer. Plos One. 11: e0150564. PMID 26991655 DOI: 10.1371/Journal.Pone.0150564  0.349
2016 Sarver AL, Murray CD, Temiz NA, Tseng YY, Bagchi A. MYC and PVT1 synergize to regulate RSPO1 levels in breast cancer. Cell Cycle (Georgetown, Tex.). 0. PMID 26889781 DOI: 10.1080/15384101.2016.1149660  0.421
2016 Sarver AE, Sarver AL, Subramanian S. Abstract B24: Identification of immunosuppressive networks in colon cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-B24  0.392
2015 Temiz NA, Moriarity BS, Wolf NK, Riordan JD, Dupuy AJ, Largaespada DA, Sarver AL. RNA sequencing of Sleeping Beauty transposon-induced tumors detect transposon-RNA fusions allowing precision analyses of forward genetic cancer screens. Genome Research. PMID 26553456 DOI: 10.1101/Gr.188649.114  0.349
2015 Heltemes-Harris LM, Larson JD, Starr TK, Hubbard GK, Sarver AL, Largaespada DA, Farrar MA. Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia. Oncogene. PMID 26500062 DOI: 10.1038/Onc.2015.405  0.374
2015 Scott MC, Sarver AL, Tomiyasu H, Cornax I, Van Etten J, Varshney J, O'Sullivan MG, Subramanian S, Modiano JF. Aberrant RB-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma. The Journal of Biological Chemistry. PMID 26378234 DOI: 10.1074/Jbc.M115.679696  0.405
2015 Sarver AE, Sarver AL, Thayanithy V, Subramanian S. Identification, by systematic RNA sequencing, of novel candidate biomarkers and therapeutic targets in human soft tissue tumors. Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 1077-88. PMID 26121316 DOI: 10.1038/Labinvest.2015.80  0.387
2015 Dorr C, Janik C, Weg M, Been RA, Bader J, Kang R, Ng B, Foran L, Landman SR, O'Sullivan MG, Steinbach M, Sarver AL, Silverstein KA, Largaespada DA, Starr TK. Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor. Molecular Cancer Research : McR. 13: 1238-47. PMID 25995385 DOI: 10.1158/1541-7786.Mcr-14-0674-T  0.371
2015 Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, et al. A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. Nature Genetics. 47: 615-24. PMID 25961939 DOI: 10.1038/Ng.3293  0.402
2015 Tonomura N, Elvers I, Thomas R, Megquier K, Turner-Maier J, Howald C, Sarver AL, Swofford R, Frantz AM, Ito D, Mauceli E, Arendt M, Noh HJ, Koltookian M, Biagi T, et al. Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. Plos Genetics. 11: e1004922. PMID 25642983 DOI: 10.1371/Journal.Pgen.1004922  0.388
2015 Rad R, Rad L, Wang W, Strong A, Ponstingl H, Bronner IF, Mayho M, Steiger K, Weber J, Hieber M, Veltkamp C, Eser S, Geumann U, Öllinger R, Zukowska M, ... ... Sarver A, et al. A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer. Nature Genetics. 47: 47-56. PMID 25485836 DOI: 10.1038/Ng.3164  0.387
2015 Sachs Z, LaRue RS, Noble K, Rathe SK, Sarver AL, Ha NA, Largaespada DA. Abstract B34: Single cell RNA sequencing identifies the NRASG12V-mediated AML self-renewal signature. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-B34  0.377
2014 Sachs Z, LaRue RS, Nguyen HT, Sachs K, Noble KE, Mohd Hassan NA, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA. NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia. Blood. 124: 3274-83. PMID 25316678 DOI: 10.1182/Blood-2013-08-521708  0.371
2014 Been RA, Linden MA, Hager CJ, DeCoursin KJ, Abrahante JE, Landman SR, Steinbach M, Sarver AL, Largaespada DA, Starr TK. Genetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in mice. Plos One. 9: e97280. PMID 24827933 DOI: 10.1371/Journal.Pone.0097280  0.381
2014 Gorden BH, Kim JH, Sarver AL, Frantz AM, Breen M, Lindblad-Toh K, O'Brien TD, Sharkey LC, Modiano JF, Dickerson EB. Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization. The American Journal of Pathology. 184: 985-95. PMID 24525151 DOI: 10.1016/J.Ajpath.2013.12.025  0.332
2014 Than BL, Goos JA, Sarver AL, O'Sullivan MG, Rod A, Starr TK, Fijneman RJ, Meijer GA, Zhao L, Zhang Y, Largaespada DA, Scott PM, Cormier RT. The role of KCNQ1 in mouse and human gastrointestinal cancers. Oncogene. 33: 3861-8. PMID 23975432 DOI: 10.1038/Onc.2013.350  0.444
2014 Sachs Z, LaRue RS, Nguyen HT, Sachs K, Hassan NAM, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA. Abstract B15: NRASG12V oncogene mediates self-renewal in a murine model of acute myelogenous leukemia Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B15  0.371
2014 Scott MC, Sarver AL, Phan F, Gupta R, Thayanithy V, Subramanian S, Modiano JF. Abstract B19: RB function as a central component of osteosarcoma behavior: A comparative assessment in dogs and humans Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B19  0.453
2014 Li L, Sarver A, Khatri R, Hajeri P, Kamenev I, Thibodeau S, Steer CJ, Subramanian S. Abstract 4368: MicroRNAs miR-503 and -182 regulate FBXW7 contributing to the malignant transformation to colon adenocarcinoma Cancer Research. 74: 4368-4368. DOI: 10.1158/1538-7445.Am2014-4368  0.329
2013 Rahrmann EP, Watson AL, Keng VW, Choi K, Moriarity BS, Beckmann DA, Wolf NK, Sarver A, Collins MH, Moertel CL, Wallace MR, Gel B, Serra E, Ratner N, Largaespada DA. Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis. Nature Genetics. 45: 756-66. PMID 23685747 DOI: 10.1038/Ng.2641  0.394
2013 MacKenzie TN, Mujumdar N, Banerjee S, Sangwan V, Sarver A, Vickers S, Subramanian S, Saluja AK. Triptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation. Molecular Cancer Therapeutics. 12: 1266-75. PMID 23635652 DOI: 10.1158/1535-7163.Mct-12-1231  0.34
2013 Wang L, Zeng X, Chen S, Ding L, Zhong J, Zhao JC, Wang L, Sarver A, Koller A, Zhi J, Ma Y, Yu J, Chen J, Huang H. BRCA1 is a negative modulator of the PRC2 complex. The Embo Journal. 32: 1584-97. PMID 23624935 DOI: 10.1038/Emboj.2013.95  0.362
2013 Watson AL, Rahrmann EP, Moriarity BS, Choi K, Conboy CB, Greeley AD, Halfond AL, Anderson LK, Wahl BR, Keng VW, Rizzardi AE, Forster CL, Collins MH, Sarver AL, Wallace MR, et al. Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance. Cancer Discovery. 3: 674-89. PMID 23535903 DOI: 10.1158/2159-8290.Cd-13-0081  0.37
2013 Krentz AD, Murphy MW, Zhang T, Sarver AL, Jain S, Griswold MD, Bardwell VJ, Zarkower D. Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line. Developmental Biology. 377: 67-78. PMID 23473982 DOI: 10.1016/J.Ydbio.2013.02.014  0.434
2013 Sarver AL, Thayanithy V, Scott MC, Cleton-Jansen AM, Hogendoorn PC, Modiano JF, Subramanian S. MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma. Orphanet Journal of Rare Diseases. 8: 7. PMID 23311495 DOI: 10.1186/1750-1172-8-7  0.358
2013 Frantz AM, Sarver AL, Ito D, Phang TL, Karimpour-Fard A, Scott MC, Valli VE, Lindblad-Toh K, Burgess KE, Husbands BD, Henson MS, Borgatti A, Kisseberth WC, Hunter LE, Breen M, et al. Molecular profiling reveals prognostically significant subtypes of canine lymphoma. Veterinary Pathology. 50: 693-703. PMID 23125145 DOI: 10.1177/0300985812465325  0.326
2013 Keng VW, Sia D, Sarver AL, Tschida BR, Fan D, Alsinet C, Solé M, Lee WL, Kuka TP, Moriarity BS, Villanueva A, Dupuy AJ, Riordan JD, Bell JB, Silverstein KA, et al. Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR. Hepatology (Baltimore, Md.). 57: 120-30. PMID 22899566 DOI: 10.1002/Hep.26004  0.34
2013 Powell TA, Moriarity BS, Sarver AL, Largaespada DA. Abstract C3: Candidate osteosarcoma metastatic drivers identified in highly clonal metastases using transposon-mediated insertional mutagenesis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C3  0.439
2013 Dorr C, Weg M, Been R, O'Sullivan MG, Sarver A, Largaespada DA, Starr TK. Abstract C43: A Sleeping Beauty forward genetic screen identifies novel cancer drivers that cooperate with Pten in lung cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C43  0.433
2012 Thayanithy V, Park C, Sarver AL, Kartha RV, Korpela DM, Graef AJ, Steer CJ, Modiano JF, Subramanian S. Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines. Plos One. 7: e43720. PMID 22957032 DOI: 10.1371/Journal.Pone.0043720  0.353
2012 Pérez-Mancera PA, Rust AG, van der Weyden L, Kristiansen G, Li A, Sarver AL, Silverstein KA, Grützmann R, Aust D, Rümmele P, Knösel T, Herd C, Stemple DL, Kettleborough R, Brosnan JA, et al. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 486: 266-70. PMID 22699621 DOI: 10.1038/Nature11114  0.421
2012 Bergerson RJ, Collier LS, Sarver AL, Been RA, Lugthart S, Diers MD, Zuber J, Rappaport AR, Nixon MJ, Silverstein KA, Fan D, Lamblin AF, Wolff L, Kersey JH, Delwel R, et al. An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model. Blood. 119: 4512-23. PMID 22427200 DOI: 10.1182/Blood-2010-04-281428  0.409
2012 Li L, Sarver AL, Alamgir S, Subramanian S. Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 571-83. PMID 22330340 DOI: 10.1038/Labinvest.2012.10  0.365
2012 Thayanithy V, Sarver AL, Kartha RV, Li L, Angstadt AY, Breen M, Steer CJ, Modiano JF, Subramanian S. Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. Bone. 50: 171-81. PMID 22037351 DOI: 10.1016/J.Bone.2011.10.012  0.315
2012 Allaei R, Starr TK, Sarver A, O'Sullivan MG, Largaespada DA. Abstract 5115: Genetic signature of histiocytic sarcoma revealed by an unbiased genetic screen in mice Cancer Research. 72: 5115-5115. DOI: 10.1158/1538-7445.Am2012-5115  0.471
2012 Fenger JM, Volinia S, Jalkanen A, Ozer HG, Sarver AL, Subramanian S, Breen M, Modiano J, London C, Kisseberth W. Abstract 184: Breed-associated differential microRNA expression in canine osteosarcoma Cancer Research. 72: 184-184. DOI: 10.1158/1538-7445.Am2012-184  0.365
2012 Conboy CB, Hatler JM, Scott PM, Sarver AL, Silverstein KA, Seshagiri S, Adams M, Lillemoe J, Dorr CR, Cormier RT, Starr TK, Largaespada DA. Abstract 108: Functional characterization of WAC, a candidate tumor suppressor gene in colorectal cancer Cancer Research. 72: 108-108. DOI: 10.1158/1538-7445.Am2012-108  0.448
2011 Olin MR, Andersen BM, Litterman AJ, Grogan PT, Sarver AL, Robertson PT, Liang X, Chen W, Parney IF, Hunt MA, Blazar BR, Ohlfest JR. Oxygen is a master regulator of the immunogenicity of primary human glioma cells. Cancer Research. 71: 6583-9. PMID 21908554 DOI: 10.1158/0008-5472.Can-11-1166  0.307
2011 Matson CK, Murphy MW, Sarver AL, Griswold MD, Bardwell VJ, Zarkower D. DMRT1 prevents female reprogramming in the postnatal mammalian testis. Nature. 476: 101-4. PMID 21775990 DOI: 10.1038/Nature10239  0.325
2011 Oberg AL, French AJ, Sarver AL, Subramanian S, Morlan BW, Riska SM, Borralho PM, Cunningham JM, Boardman LA, Wang L, Smyrk TC, Asmann Y, Steer CJ, Thibodeau SN. miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. Plos One. 6: e20465. PMID 21694772 DOI: 10.1371/Journal.Pone.0020465  0.33
2011 Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF. Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone. 49: 356-67. PMID 21621658 DOI: 10.1016/J.Bone.2011.05.008  0.386
2011 Krentz AD, Murphy MW, Sarver AL, Griswold MD, Bardwell VJ, Zarkower D. DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary. Developmental Biology. 356: 63-70. PMID 21621532 DOI: 10.1016/J.Ydbio.2011.05.658  0.35
2011 Billington CJ, Ng B, Forsman C, Schmidt B, Bagchi A, Symer DE, Schotta G, Gopalakrishnan R, Sarver AL, Petryk A. The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice. Developmental Biology. 355: 21-31. PMID 21549111 DOI: 10.1016/J.Ydbio.2011.04.026  0.366
2011 Starr TK, Scott PM, Marsh BM, Zhao L, Than BL, O'Sullivan MG, Sarver AL, Dupuy AJ, Largaespada DA, Cormier RT. A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 5765-70. PMID 21436051 DOI: 10.1073/Pnas.1018012108  0.378
2011 Starr TK, Allaei R, Sarver A, Silverstein K, O'Sullivan MG, Cormier R, Largaespada D. Abstract 2859: Identification of driver mutations in colon cancer using Sleeping Beauty mutagenesis Cancer Research. 71: 2859-2859. DOI: 10.1158/1538-7445.Am2011-2859  0.417
2010 Sarver AL, Li L, Subramanian S. MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration. Cancer Research. 70: 9570-80. PMID 21118966 DOI: 10.1158/0008-5472.Can-10-2074  0.39
2010 Castro RE, Ferreira DM, Zhang X, Borralho PM, Sarver AL, Zeng Y, Steer CJ, Kren BT, Rodrigues CM. Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G887-97. PMID 20689055 DOI: 10.1152/Ajpgi.00216.2010  0.309
2010 Murphy MW, Sarver AL, Rice D, Hatzi K, Ye K, Melnick A, Heckert LL, Zarkower D, Bardwell VJ. Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis. Proceedings of the National Academy of Sciences of the United States of America. 107: 13360-5. PMID 20616082 DOI: 10.1073/Pnas.1006243107  0.414
2010 Kumar AR, Sarver AL, Wu B, Kersey JH. Meis1 maintains stemness signature in MLL-AF9 leukemia. Blood. 115: 3642-3. PMID 20430967 DOI: 10.1182/Blood-2010-01-264564  0.364
2010 Sarver AL, Phalak R, Thayanithy V, Subramanian S. S-MED: sarcoma microRNA expression database. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 753-61. PMID 20212452 DOI: 10.1038/Labinvest.2010.53  0.33
2010 Keng VW, Ryan BJ, Silverstein KAT, Sarver A, Fan D, Dupuy AJ, Jenkins NA, Copeland NG, Largaespada DA. Abstract 4182: A screen for genes that define the strong gender bias nature of hepatocellular carcinoma using a transposon mutagenesis murine model Cancer Research. 70: 4182-4182. DOI: 10.1158/1538-7445.Am10-4182  0.368
2010 Sachdev D, Sarver A. Abstract 3295: The type I insulin-like growth factor receptor (IGF1R) pathway driven metastasis signature correlates with poor prognosis and decreased distant metastasis-free survival in human breast cancer Cancer Research. 70: 3295-3295. DOI: 10.1158/1538-7445.Am10-3295  0.41
2009 Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D. The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency. Proceedings of the National Academy of Sciences of the United States of America. 106: 22323-8. PMID 20007774 DOI: 10.1073/Pnas.0905431106  0.451
2009 Sarver AL, French AJ, Borralho PM, Thayanithy V, Oberg AL, Silverstein KA, Morlan BW, Riska SM, Boardman LA, Cunningham JM, Subramanian S, Wang L, Smyrk TC, Rodrigues CM, Thibodeau SN, et al. Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. Bmc Cancer. 9: 401. PMID 19922656 DOI: 10.1186/1471-2407-9-401  0.398
2009 Starr TK, Allaei R, Silverstein KA, Staggs RA, Sarver AL, Bergemann TL, Gupta M, O'Sullivan MG, Matise I, Dupuy AJ, Collier LS, Powers S, Oberg AL, Asmann YW, Thibodeau SN, et al. A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. Science (New York, N.Y.). 323: 1747-50. PMID 19251594 DOI: 10.1126/Science.1163040  0.388
2009 Keng VW, Villanueva A, Chiang DY, Dupuy AJ, Ryan BJ, Matise I, Silverstein KA, Sarver A, Starr TK, Akagi K, Tessarollo L, Collier LS, Powers S, Lowe SW, Jenkins NA, et al. A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nature Biotechnology. 27: 264-74. PMID 19234449 DOI: 10.1038/Nbt.1526  0.367
2009 Kren BT, Wong PY, Sarver A, Zhang X, Zeng Y, Steer CJ. MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis. Rna Biology. 6: 65-72. PMID 19106625 DOI: 10.4161/Rna.6.1.7534  0.338
2009 Bergerson RJ, Collier LS, Lugthart S, Allaei R, Nixon MJ, Silverstein KA, Sarver A, Fan DF, Lamblin AJ, Wolff L, Kersey JH, O'Sullivan MG, Delwel R, Kogan SC, Adams DJ, et al. An Insertional Mutagenesis Screen for Genes That Cooperate with Mll-AF9 in Leukemogenesis. Blood. 114: 3962-3962. DOI: 10.1182/Blood.V114.22.3962.3962  0.378
2009 Sarver A, Sachdev D. Abstract B239: Profiling the type I insulin‐like growth factor receptor (IGF1R) pathway regulated metastasis signature Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B239  0.425
2009 Starr TK, Allaei R, O'Sullivan MG, Sarver AL, Dupuy AJ, Jenkins NA, Copeland NG, Largaespada DA. Abstract A14: A forward genetic screen for genes that cooperate with PTEN in lung cancer development Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A14  0.379
2006 Zhu J, Jambhekar A, Sarver A, DeRisi J. A Bayesian network driven approach to model the transcriptional response to nitric oxide in Saccharomyces cerevisiae. Plos One. 1: e94. PMID 17183726 DOI: 10.1371/Journal.Pone.0000094  0.678
2005 Sarver A, DeRisi J. Fzf1p regulates an inducible response to nitrosative stress in Saccharomyces cerevisiae. Molecular Biology of the Cell. 16: 4781-91. PMID 16014606 DOI: 10.1091/Mbc.E05-05-0436  0.531
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