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Holly A. Gratkowski, Ph.D. - Publications

Affiliations: 
2002 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Organic Chemistry, Chemical Biology, De Novo Protein Design
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2004 Lear JD, Stouffer AL, Gratkowski H, Nanda V, Degrado WF. Association of a model transmembrane peptide containing gly in a heptad sequence motif. Biophysical Journal. 87: 3421-9. PMID 15315956 DOI: 10.1529/Biophysj.103.032839  0.437
2003 Lear JD, Gratkowski H, Adamian L, Liang J, DeGrado WF. Position-dependence of stabilizing polar interactions of asparagine in transmembrane helical bundles. Biochemistry. 42: 6400-7. PMID 12767221 DOI: 10.1021/Bi020573J  0.656
2003 Li R, Mitra N, Gratkowski H, Vilaire G, Litvinov R, Nagasami C, Weisel JW, Lear JD, DeGrado WF, Bennett JS. Activation of integrin alphaIIbbeta3 by modulation of transmembrane helix associations. Science (New York, N.Y.). 300: 795-8. PMID 12730600 DOI: 10.1126/Science.1079441  0.552
2003 DeGrado WF, Gratkowski H, Lear JD. How do helix-helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles. Protein Science : a Publication of the Protein Society. 12: 647-65. PMID 12649422 DOI: 10.1110/Ps.0236503  0.611
2002 Gratkowski H, Dai QH, Wand AJ, DeGrado WF, Lear JD. Cooperativity and specificity of association of a designed transmembrane peptide. Biophysical Journal. 83: 1613-9. PMID 12202385 DOI: 10.1016/S0006-3495(02)73930-1  0.674
2001 Lear JD, Gratkowski H, DeGrado WF. De novo design, synthesis and characterization of membrane-active peptides Biochemical Society Transactions. 29: 559-564. PMID 11498028 DOI: 10.1042/Bst0290559  0.708
2001 Gratkowski H, Lear JD, DeGrado WF. Polar side chains drive the association of model transmembrane peptides Proceedings of the National Academy of Sciences of the United States of America. 98: 880-885. PMID 11158564 DOI: 10.1073/Pnas.98.3.880  0.685
2000 Choma C, Gratkowski H, Lear JD, DeGrado WF. Asparagine-mediated self-association of a model transmembrane helix. Nature Structural Biology. 7: 161-6. PMID 10655620 DOI: 10.1038/72440  0.704
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