| Year |
Citation |
Score |
| 2022 |
Wander SA, Hasserjian RP, Oduro K, Glomski K, Nardi V, Cote GM, Graubert TA, Brunner AM, Chen YA, Fathi AT. Combined Targeted Therapy for -Mutant, Treatment-Related Acute Myeloid Leukemia. Jco Precision Oncology. 1: 1-7. PMID 35172484 DOI: 10.1200/PO.16.00032 |
0.35 |
|
| 2021 |
Wadugu BA, Nonavinkere Srivatsan S, Heard A, Alberti MO, Ndonwi M, Liu J, Grieb S, Bradley J, Shao J, Ahmed T, Shirai CL, Khanna A, Fei DL, Miller CA, Graubert TA, et al. U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice. The Journal of Clinical Investigation. PMID 34546980 DOI: 10.1172/JCI141401 |
0.344 |
|
| 2020 |
Malcovati L, Stevenson K, Papaemmanuil E, Neuberg D, Bejar R, Boultwood J, Bowen DT, Campbell PJ, Ebert BL, Fenaux P, Haferlach T, Heuser M, Jansen JH, Komrokji RS, Maciejewski JP, ... ... Graubert TA, et al. SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM). Blood. PMID 32347921 DOI: 10.1182/Blood.2020004850 |
0.459 |
|
| 2020 |
Hasserjian RP, Steensma DP, Graubert TA, Ebert BL. Clonal Hematopoiesis and Measurable Residual Disease Assessment in Acute Myeloid Leukemia. Blood. PMID 32232484 DOI: 10.1182/Blood.2019004770 |
0.473 |
|
| 2019 |
Narayan R, Blonquist TM, Emadi A, Hasserjian RP, Burke M, Lescinskas C, Neuberg DS, Brunner AM, Hobbs G, Hock H, McAfee SL, Chen YB, Attar E, Graubert TA, Bertoli C, et al. A phase 1 study of the antibody-drug conjugate brentuximab vedotin with re-induction chemotherapy in patients with CD30-expressing relapsed/refractory acute myeloid leukemia. Cancer. PMID 31860140 DOI: 10.1002/Cncr.32657 |
0.315 |
|
| 2019 |
Brunner AM, Blonquist TM, DeAngelo DJ, McMasters M, Fell G, Hermance NM, Winer ES, Lindsley RC, Hobbs GS, Amrein PC, Hock HR, Steensma DP, Garcia JS, Luskin MR, Stone RM, ... ... Graubert TA, et al. Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial. The Lancet. Haematology. PMID 31837959 DOI: 10.1016/S2352-3026(19)30203-0 |
0.355 |
|
| 2019 |
van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, et al. Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. Cell. PMID 30827681 DOI: 10.1016/J.Cell.2019.01.031 |
0.423 |
|
| 2019 |
Haase D, Stevenson KE, Neuberg D, Maciejewski JP, Nazha A, Sekeres MA, Ebert BL, Garcia-Manero G, Haferlach C, Haferlach T, Kern W, Ogawa S, Nagata Y, Yoshida K, Graubert TA, et al. TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia. PMID 30635634 DOI: 10.1038/S41375-018-0351-2 |
0.456 |
|
| 2018 |
Brunner AM, Neuberg DS, Wander SA, Sadrzadeh H, Ballen KK, Amrein PC, Attar E, Hobbs GS, Chen YB, Perry A, Connolly C, Joseph C, Burke M, Ramos A, Galinsky I, ... ... Graubert TA, et al. Isocitrate dehydrogenase 1 and 2 mutations, 2-hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia. Cancer. PMID 30422308 DOI: 10.1002/Cncr.31729 |
0.478 |
|
| 2018 |
Christopher MJ, Petti AA, Rettig MP, Miller CA, Chendamarai E, Duncavage EJ, Klco JM, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Wilson RK, Wartman LD, Welch JS, Heath SE, ... ... Graubert TA, et al. Immune Escape of Relapsed AML Cells after Allogeneic Transplantation. The New England Journal of Medicine. PMID 30380364 DOI: 10.1056/Nejmoa1808777 |
0.753 |
|
| 2018 |
Duncavage EJ, Jacoby MA, Chang GS, Miller CA, Edwin N, Shao J, Elliott K, Robinson J, Abel H, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Brendel K, Saba R, ... ... Graubert TA, et al. Mutation Clearance after Transplantation for Myelodysplastic Syndrome. The New England Journal of Medicine. 379: 1028-1041. PMID 30207916 DOI: 10.1056/Nejmoa1804714 |
0.805 |
|
| 2018 |
Nguyen HD, Leong WY, Li W, Reddy PNG, Sullivan JD, Walter MJ, Zou L, Graubert TA. Spliceosome Mutations Induce R loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndrome. Cancer Research. PMID 30054334 DOI: 10.1158/0008-5472.Can-17-3970 |
0.435 |
|
| 2018 |
Brunner AM, Weng S, Cronin A, Fathi AT, Habib AR, Stone R, Graubert T, Steensma DP, Abel GA. Impact of Lenalidomide Use among Non-Transfusion Dependent Patients with Myelodysplastic Syndromes. American Journal of Hematology. PMID 30033577 DOI: 10.1002/Ajh.25166 |
0.345 |
|
| 2018 |
Patel SS, Kuo FC, Gibson CJ, Steensma DP, Soiffer RJ, Alyea EP, Chen YA, Fathi AT, Graubert TA, Brunner AM, Wadleigh M, Stone RM, DeAngelo DJ, Nardi V, Hasserjian RP, et al. High NPM1 mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML. Blood. PMID 29724895 DOI: 10.1182/Blood-2018-01-828467 |
0.494 |
|
| 2018 |
Jacoby MA, Duncavage EJ, Chang GS, Miller CA, Shao J, Elliott K, Robinson J, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Pusic I, Welch JS, Link DC, DiPersio JF, ... ... Graubert TA, et al. Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant. Jci Insight. 3. PMID 29515031 DOI: 10.1172/Jci.Insight.98962 |
0.711 |
|
| 2018 |
Wong TN, Miller CA, Jotte MRM, Bagegni N, Baty JD, Schmidt AP, Cashen AF, Duncavage EJ, Helton NM, Fiala M, Fulton RS, Heath SE, Janke M, Luber K, Westervelt P, ... ... Graubert TA, et al. Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential. Nature Communications. 9: 455. PMID 29386642 DOI: 10.1038/S41467-018-02858-0 |
0.821 |
|
| 2018 |
Brunner AM, Graubert TA. Genomics in childhood acute myeloid leukemia comes of age. Nature Medicine. 24: 7-9. PMID 29315296 DOI: 10.1038/Nm.4469 |
0.34 |
|
| 2018 |
Brunner AM, Blonquist TM, DeAngelo DJ, McMasters M, Winer ES, Hobbs GS, Amrein PC, Hock H, Steensma DP, Garcia JS, Luskin MR, Stone RM, Ballen KK, Rosenblatt J, Avigan DE, ... ... Graubert TA, et al. Phase II Clinical Trial of Alisertib, an Aurora a Kinase Inhibitor, in Combination with Induction Chemotherapy in High-Risk, Untreated Patients with Acute Myeloid Leukemia Blood. 132: 766-766. DOI: 10.1182/Blood-2018-99-115145 |
0.368 |
|
| 2018 |
Van Galen P, Hovestadt V, Wadsworth II M, Hughes T, Griffin GK, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, et al. Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity Blood. 132: 542-542. DOI: 10.1182/Blood-2018-99-113502 |
0.45 |
|
| 2018 |
Chen EC, Hobbs GS, Amrein PC, Graubert TA, Fathi AT, Brunner AM. Clinical Outcomes Following Frontline Chemotherapy for Patients with Myeloid Malignancies Harboring Splicing Factor Mutations Blood. 132: 4364-4364. DOI: 10.1182/Blood-2018-99-111982 |
0.49 |
|
| 2017 |
Shirai CL, White BS, Tripathi M, Tapia R, Ley JN, Ndonwi M, Kim S, Shao J, Carver A, Saez B, Fulton RS, Fronick C, O'Laughlin M, Lagisetti C, Webb TR, ... Graubert TA, et al. Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome. Nature Communications. 8: 14060. PMID 28067246 DOI: 10.1038/Ncomms14060 |
0.477 |
|
| 2017 |
Brunner AM, Weng S, Cronin AM, Fathi AT, Stone RM, Graubert TA, Steensma DP, Abel GA. Prevalence and complications associated with off-label use of lenalidomide in older patients with myelodysplastic syndromes (MDS). Journal of Clinical Oncology. 35: 7054-7054. DOI: 10.1200/Jco.2017.35.15_Suppl.7054 |
0.308 |
|
| 2017 |
Wong TN, Miller CA, Jotte MR, Bagegni N, Baty JD, Schmidt AE, Cashen AF, Duncavage EJ, Helton NM, Fiala MA, Fulton RS, Heath SE, Janke M, Luber K, Westervelt P, ... ... Graubert TA, et al. Cellular Stressors Contribute to the Expansion of Multiple Hematopoietic Clones of Varying Leukemic Potential Blood. 130: 469-469. DOI: 10.1182/Blood.V130.Suppl_1.469.469 |
0.772 |
|
| 2017 |
Leong WY, Nguyen HD, Li W, Walter MJ, Zou L, Graubert TA. Spliceosomal Mutations Induce R Loop-Associated ATR Signaling Blood. 130: 116-116. DOI: 10.1182/Blood.V130.Suppl_1.116.116 |
0.403 |
|
| 2016 |
Fathi AT, Wander SA, Blonquist TM, Brunner AM, Amrein PC, Supko J, Hermance NM, Manning AL, Sadrzadeh H, Ballen KK, Attar EC, Graubert TA, Hobbs G, Joseph C, Perry AM, et al. Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia. Haematologica. PMID 28034990 DOI: 10.3324/Haematol.2016.158394 |
0.337 |
|
| 2016 |
Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, ... ... Graubert TA, et al. TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes. The New England Journal of Medicine. 375: 2023-2036. PMID 27959731 DOI: 10.1056/Nejmoa1605949 |
0.808 |
|
| 2016 |
Saez B, Walter MJ, Graubert TA. Splicing factor gene mutations in hematologic malignancies. Blood. PMID 27940478 DOI: 10.1182/Blood-2016-10-692400 |
0.473 |
|
| 2016 |
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Elliott K, Reinick T, Fulton RS, Fronick CC, O'Laughlin M, Ganel L, Abboud CN, Cashen AF, ... ... Graubert TA, et al. Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy. Leukemia. PMID 27740633 DOI: 10.1038/Leu.2016.282 |
0.712 |
|
| 2016 |
Griffith M, Griffith OL, Krysiak K, Skidmore ZL, Christopher MJ, Klco JM, Ramu A, Lamprecht TL, Wagner AH, Campbell KM, Lesurf R, Hundal J, Zhang J, Spies NC, Ainscough BJ, ... ... Graubert TA, et al. Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B lymphoblastic leukemia. Experimental Hematology. PMID 27181063 DOI: 10.1016/J.Exphem.2016.04.011 |
0.793 |
|
| 2016 |
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, ... ... Graubert TA, et al. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 29: 574-86. PMID 27070704 DOI: 10.1016/J.Ccell.2016.03.008 |
0.312 |
|
| 2016 |
Walter MJ, Graubert TA. Clinical Implications of Spliceosome Mutations: Epidemiology, Clonal Hematopoiesis, and Potential Therapeutic Strategies Blood. 128: SCI-19-SCI-19. DOI: 10.1182/Blood.V128.22.Sci-19.Sci-19 |
0.515 |
|
| 2016 |
Duncavage EJ, Jacoby MA, Miller C, Chang GS, Shao J, Elliot K, Fronick C, O'Laughlin M, Fulton R, Wilson RK, Graubert TA, Walter MJ. Rare Pre-Existing MDS Subclones Contribute to Secondary AML Progression Blood. 128: 959-959. DOI: 10.1182/Blood.V128.22.959.959 |
0.497 |
|
| 2016 |
Jacoby MA, Duncavage EJ, Chang GS, Miller CA, Shao J, Elliott K, Fulton RS, Fronick C, O'Laughlin M, Link DC, DiPersio JF, Westervelt P, Ley TJ, Graubert TA, Walter MJ, et al. Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant Blood. 128: 5506-5506. DOI: 10.1182/Blood.V128.22.5506.5506 |
0.739 |
|
| 2015 |
Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, ... ... Graubert TA, et al. Patterns and functional implications of rare germline variants across 12 cancer types. Nature Communications. 6: 10086. PMID 26689913 DOI: 10.1038/Ncomms10086 |
0.522 |
|
| 2015 |
Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, et al. Rapid expansion of pre-existing non-leukemic hematopoietic clones frequently follows induction therapy for de novo AML. Blood. PMID 26631115 DOI: 10.1182/Blood-2015-10-677021 |
0.721 |
|
| 2015 |
Churpek JE, Pyrtel K, Kanchi KL, Shao J, Koboldt D, Miller CA, Shen D, Fulton R, O'Laughlin M, Fronick C, Pusic I, Uy GL, Braunstein EM, Levis M, Ross J, ... ... Graubert TA, et al. Genomic analysis of germline and somatic variants in familial myelodysplasia/acute myeloid leukemia. Blood. PMID 26492932 DOI: 10.1182/Blood-2015-04-641100 |
0.706 |
|
| 2015 |
Platt MY, Fathi AT, Borger DR, Brunner AM, Hasserjian RP, Balaj L, Lum A, Yip S, Dias-Santagata D, Zheng Z, Le LP, Graubert TA, Iafrate AJ, Nardi V. Detection of Dual IDH1 and IDH2 Mutations by Targeted Next-Generation Sequencing in Acute Myeloid Leukemia and Myelodysplastic Syndromes. The Journal of Molecular Diagnostics : Jmd. PMID 26331834 DOI: 10.1016/J.Jmoldx.2015.06.004 |
0.499 |
|
| 2015 |
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, ... ... Graubert TA, et al. Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia. Jama. 314: 811-22. PMID 26305651 DOI: 10.1001/Jama.2015.9643 |
0.772 |
|
| 2015 |
Shirai CL, Ley JN, White BS, Kim S, Tibbitts J, Shao J, Ndonwi M, Wadugu B, Duncavage EJ, Okeyo-Owuor T, Liu T, Griffith M, McGrath S, Magrini V, Fulton RS, ... ... Graubert TA, et al. Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo. Cancer Cell. 27: 631-43. PMID 25965570 DOI: 10.1016/J.Ccell.2015.04.008 |
0.827 |
|
| 2015 |
El-Jawahri A, Traeger L, Kuzmuk K, Eusebio J, Vandusen H, Keenan T, Shin J, Gallagher ER, Greer JA, Pirl WF, Jackson VA, Ballen KK, Spitzer TR, Graubert TA, McAfee S, et al. Prognostic understanding, quality of life and mood in patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplantation. PMID 25961772 DOI: 10.1182/Blood.V124.21.1296.1296 |
0.321 |
|
| 2015 |
Kotini AG, Chang CJ, Boussaad I, Delrow JJ, Dolezal EK, Nagulapally AB, Perna F, Fishbein GA, Klimek VM, Hawkins RD, Huangfu D, Murry CE, Graubert T, Nimer SD, Papapetrou EP. Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells. Nature Biotechnology. 33: 646-55. PMID 25798938 DOI: 10.1038/Nbt.3178 |
0.374 |
|
| 2015 |
Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, ... ... Graubert TA, et al. Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. Nature. 518: 552-5. PMID 25487151 DOI: 10.1038/Nature13968 |
0.726 |
|
| 2015 |
Okeyo-Owuor T, White BS, Chatrikhi R, Mohan DR, Kim S, Griffith M, Ding L, Ketkar-Kulkarni S, Hundal J, Laird KM, Kielkopf CL, Ley TJ, Walter MJ, Graubert TA. U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing. Leukemia. 29: 909-17. PMID 25311244 DOI: 10.1038/Leu.2014.303 |
0.81 |
|
| 2015 |
Bejar R, Papaemmanuil E, Haferlach T, Garcia-Manero G, Maciejewski JP, Sekeres MA, Walter MJ, Graubert TA, Cazzola M, Malcovati L, Ogawa S, Fenaux P, Hellstrom-Lindberg E, Kern W, Boultwood J, et al. Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee Blood. 126: 907-907. DOI: 10.1182/Blood.V126.23.907.907 |
0.462 |
|
| 2015 |
Wong TN, Klco JM, Demeter R, Miller CA, Petti A, Havey N, Fulton R, Heath S, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert T, Wilson RK, et al. Non-Malignant Oligoclonal Hematopoiesis Commonly Follows Cytoreductive Chemotherapy in Adult De Novo AML Patients Blood. 126: 686-686. DOI: 10.1182/Blood.V126.23.686.686 |
0.736 |
|
| 2015 |
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Fulton RS, Fronick CC, O'Laughlin M, Abboud CN, Cashen AF, DiPersio JF, Wilson RK, Link DC, ... ... Graubert TA, et al. Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy Blood. 126: 610-610. DOI: 10.1182/blood.v126.23.610.610 |
0.723 |
|
| 2015 |
Shirai CL, Tripathi M, Ley JN, Ndonwi M, White BS, Tapia R, Saez B, Bertino A, Shao J, Kim S, Webb TR, Graubert TA, Walter MJ. Preclinical Activity of Splicing Modulators in U2AF1 Mutant MDS/AML Blood. 126: 1653-1653. DOI: 10.1182/Blood.V126.23.1653.1653 |
0.524 |
|
| 2015 |
Shirai CL, Ley JN, White B, Tibbitts J, Shao J, Ndonwi M, Kim S, Okeyo-Owuor T, Graubert TA, Walter MJ. Abstract PR06: Mutant U2AF1 alters hematopoiesis and pre-mRNA splicing in transgenic mice. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-Pr06 |
0.823 |
|
| 2015 |
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, ... ... Graubert TA, et al. Abstract PR11: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr11 |
0.777 |
|
| 2015 |
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, ... ... Graubert TA, et al. Abstract PR03: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr03 |
0.777 |
|
| 2015 |
Kotini AG, Chang CJ, Graubert T, Nimer SD, Papapetrou E. 28 Functional Dissection Of Del(7Q)-Mds With Patient-Derived Induced Pluripotent Stem Cells Leukemia Research. 39. DOI: 10.1016/S0145-2126(15)30029-1 |
0.325 |
|
| 2014 |
Traeger L, Eusebio J, Kuzmuk K, Vandusen H, Shin J, Gallagher ER, Greer JA, Pirl WF, Ballen KK, Spitzer TR, Graubert TA, McAfee SL, Dey B, Jackson VA, Chen YA, et al. Prognostic understanding, quality of life (QOL), and mood in patients undergoing hematopoietic stem cell transplantation (HCT). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 219. PMID 28142832 DOI: 10.1200/Jco.2014.32.31_Suppl.219 |
0.31 |
|
| 2014 |
Lu EP, McLellan M, Ding L, Fulton R, Mardis ER, Wilson RK, Miller CA, Westervelt P, DiPersio JF, Link DC, Walter MJ, Ley TJ, Graubert TA. Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice. Blood. 124: 3887-95. PMID 25349173 DOI: 10.1182/Blood-2014-06-582551 |
0.789 |
|
| 2014 |
Graubert T, Stone R. AML Genomics for the Clinician Seminars in Hematology. 51: 322-329. PMID 25311744 DOI: 10.1053/J.Seminhematol.2014.08.006 |
0.447 |
|
| 2014 |
Graubert T. AML Genomics: Introduction Seminars in Hematology. 51: 249. PMID 25311737 DOI: 10.1053/J.Seminhematol.2014.08.008 |
0.31 |
|
| 2014 |
Graubert TA. A call to action for acute lymphoblastic leukemia. The New England Journal of Medicine. 371: 1064-6. PMID 25207770 DOI: 10.1056/Nejme1407477 |
0.344 |
|
| 2014 |
Miller CA, White BS, Dees ND, Griffith M, Welch JS, Griffith OL, Vij R, Tomasson MH, Graubert TA, Walter MJ, Ellis MJ, Schierding W, DiPersio JF, Ley TJ, Mardis ER, et al. SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution. Plos Computational Biology. 10: e1003665. PMID 25102416 DOI: 10.1371/Journal.Pcbi.1003665 |
0.578 |
|
| 2014 |
Tabor HK, Auer PL, Jamal SM, Chong JX, Yu JH, Gordon AS, Graubert TA, O'Donnell CJ, Rich SS, Nickerson DA, Bamshad MJ. Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results. American Journal of Human Genetics. 95: 183-93. PMID 25087612 DOI: 10.1016/J.Ajhg.2014.07.006 |
0.339 |
|
| 2014 |
Hughes AE, Magrini V, Demeter R, Miller CA, Fulton R, Fulton LL, Eades WC, Elliott K, Heath S, Westervelt P, Ding L, Conrad DF, White BS, Shao J, Link DC, ... ... Graubert TA, et al. Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing. Plos Genetics. 10: e1004462. PMID 25010716 DOI: 10.1371/Journal.Pgen.1004462 |
0.684 |
|
| 2014 |
Graubert TA, Brunner AM, Fathi AT. New molecular abnormalities and clonal architecture in AML: from reciprocal translocations to whole-genome sequencing. American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting. e334-40. PMID 24857122 DOI: 10.14694/EdBook_AM.2014.34.e334 |
0.397 |
|
| 2014 |
Klco JM, Spencer DH, Miller CA, Griffith M, Lamprecht TL, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Fulton RS, Eades WC, Link DC, Graubert TA, Walter MJ, Mardis ER, et al. Functional heterogeneity of genetically defined subclones in acute myeloid leukemia. Cancer Cell. 25: 379-92. PMID 24613412 DOI: 10.1016/J.Ccr.2014.01.031 |
0.687 |
|
| 2014 |
Kanchi KL, Johnson KJ, Lu C, McLellan MD, Leiserson MD, Wendl MC, Zhang Q, Koboldt DC, Xie M, Kandoth C, McMichael JF, Wyczalkowski MA, Larson DE, Schmidt HK, Miller CA, ... ... Graubert TA, et al. Integrated analysis of germline and somatic variants in ovarian cancer. Nature Communications. 5: 3156. PMID 24448499 DOI: 10.1038/Ncomms4156 |
0.384 |
|
| 2014 |
Shirai CL, Ley JN, White BS, Tibbitts J, Shao J, Ndonwi M, Kim S, Wadugu B, Okeyo-Owuor T, Graubert TA, Walter MJ. Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing in Transgenic Mice Blood. 124: 827-827. DOI: 10.1182/Blood.V124.21.827.827 |
0.828 |
|
| 2014 |
Bejar R, Papaemmanuil E, Haferlach T, Garcia-Manero G, Maciejewski JP, Sekeres MA, Walter MJ, Graubert TA, Cazzola M, Malcovati L, Campbell PJ, Ogawa S, Boultwood J, Bowen D, Tauro S, et al. TP53 Mutation Status Divides MDS Patients with Complex Karyotypes into Distinct Prognostic Risk Groups: Analysis of Combined Datasets from the International Working Group for MDS-Molecular Prognosis Committee Blood. 124: 532-532. DOI: 10.1182/Blood.V124.21.532.532 |
0.481 |
|
| 2014 |
Kotini A, Delrow JJ, Graubert TA, Nimer S, Papapetrou EP. Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS Blood. 124: 524-524. DOI: 10.1182/Blood.V124.21.524.524 |
0.43 |
|
| 2014 |
Fathi AT, Wander SA, Blonquist TM, Ballen KK, Attar EC, McAfee SL, Chen Y, Graubert TA, Brunner AM, Joseph C, Perry AM, Burke M, Silver R, Ramos AY, Connolly C, et al. A Phase I Study of the Aurora a Kinase Inhibitor Alisertib in Combination with 7+3 Induction Chemotherapy in Patients with Acute Myeloid Leukemia Blood. 124: 119-119. DOI: 10.1182/Blood.V124.21.119.119 |
0.379 |
|
| 2013 |
Janke MR, Baty JD, Graubert TA. SWR/J mice are susceptible to alkylator-induced myeloid leukemia. Blood Cancer Journal. 3: e161. PMID 24241401 DOI: 10.1038/Bcj.2013.59 |
0.809 |
|
| 2013 |
Walter MJ, Shen D, Shao J, Ding L, White BS, Kandoth C, Miller CA, Niu B, McLellan MD, Dees ND, Fulton R, Elliot K, Heath S, Grillot M, Westervelt P, ... ... Graubert TA, et al. Clonal diversity of recurrently mutated genes in myelodysplastic syndromes. Leukemia. 27: 1275-82. PMID 23443460 DOI: 10.1038/Leu.2013.58 |
0.727 |
|
| 2013 |
Shirai CL, Tibbitts J, Shao J, Ndonwi M, Ley JN, Kim S, Tripathi M, Okeyo-Owuor T, Graubert TA, Walter MJ. Mutant U2AF1 Expression Alters Hematopoiesis In Transgenic Mice Blood. 122: 99-99. DOI: 10.1182/Blood.V122.21.99.99 |
0.812 |
|
| 2013 |
Neal Wong T, Ramsingh G, Young A, Shen D, Miller C, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch J, Walter MJ, Graubert T, DiPersio JF, et al. The Role Of Early TP53 Mutations On The Evolution Of Therapy-Related AML Blood. 122: 5-5. DOI: 10.1182/Blood.V122.21.5.5 |
0.729 |
|
| 2013 |
Ghobadi A, Fiala MA, Abboud CN, Cashen AF, Eissenberg L, Graubert T, Jacoby MA, Pusic I, Schroeder MA, Stockerl-Goldstein KE, Tomasson MH, Uy GL, Vij R, Walter MJ, DiPersio JF, et al. A Phase I Study Of Azacitidine After Donor Lymphocyte Infusion For Relapsed Acute Myeloid Leukemia Post Allogeneic Stem Cell Transplantation Blood. 122: 3320-3320. DOI: 10.1182/Blood.V122.21.3320.3320 |
0.392 |
|
| 2013 |
Okeyo-Owuor T, White BS, Mohan D, Griffith M, Walter MJ, Graubert T. Allele-Specific Effects of U2AF1 Mutations on Alternative Splicing Blood. 122: 2748-2748. DOI: 10.1182/Blood.V122.21.2748.2748 |
0.834 |
|
| 2013 |
Dees ND, Miller CA, White BS, Schierding W, Vij R, Tomasson MH, Welch JS, Graubert TA, Walter MJ, Ley TJ, DiPersio JF, Mardis ER, Wilson RK, Ding L. Abstract LB-232: Tumor clonality detection using next generation sequencing data. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-232 |
0.555 |
|
| 2013 |
Graubert TA, Baker S, Potter PM, Tripathi M, Walter M, Palacios G, Webb TR. Abstract 1125: Spliceosome-targeted antitumor drug discovery. Cancer Research. 73: 1125-1125. DOI: 10.1158/1538-7445.Am2013-1125 |
0.418 |
|
| 2012 |
Auer PL, Johnsen JM, Johnson AD, Logsdon BA, Lange LA, Nalls MA, Zhang G, Franceschini N, Fox K, Lange EM, Rich SS, O'Donnell CJ, Jackson RD, Wallace RB, Chen Z, ... Graubert TA, et al. Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. American Journal of Human Genetics. 91: 794-808. PMID 23103231 DOI: 10.1016/J.Ajhg.2012.08.031 |
0.368 |
|
| 2012 |
Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, Wartman LD, Lamprecht TL, Liu F, Xia J, Kandoth C, Fulton RS, McLellan MD, Dooling DJ, Wallis JW, ... ... Graubert TA, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 150: 264-78. PMID 22817890 DOI: 10.1016/J.Cell.2012.06.023 |
0.733 |
|
| 2012 |
Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, Larson DE, McLellan MD, Dooling D, Abbott R, Fulton R, Magrini V, Schmidt H, Kalicki-Veizer J, O'Laughlin M, ... ... Graubert TA, et al. Clonal architecture of secondary acute myeloid leukemia. The New England Journal of Medicine. 366: 1090-8. PMID 22417201 DOI: 10.1056/Nejmoa1106968 |
0.735 |
|
| 2012 |
Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF, Wallis JW, Lu C, Shen D, Harris CC, ... ... Graubert TA, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 481: 506-10. PMID 22237025 DOI: 10.1038/Nature10738 |
0.794 |
|
| 2012 |
Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nature Genetics. 44: 53-7. PMID 22158538 DOI: 10.1038/Ng.1031 |
0.825 |
|
| 2012 |
Ramsingh G, Shen D, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch JS, Walter MJ, Graubert T, DiPersio JF, Ley TJ, Wilson RK, Link DC. Whole Genome Sequencing of Therapy-Related Acute Myeloid Leukemia Blood. 120: 784-784. DOI: 10.1182/Blood.V120.21.784.784 |
0.738 |
|
| 2012 |
Tripathi M, Lunn CL, Okeyo-Owuor T, Walter MJ, Webb TR, Graubert T. Sudemycin Selectively Inhibits Growth of Primary Murine Hematopoietic Cells Expressing Mutant U2AF1 Blood. 120: 554-554. DOI: 10.1182/Blood.V120.21.554.554 |
0.833 |
|
| 2012 |
Lunn CL, Tibbitts J, Ley JN, Shao J, Graubert T, Walter MJ. Mutant U2AF1(S34F) Expression Alters Hematopoiesis in Mice Blood. 120: 553-553. DOI: 10.1182/Blood.V120.21.553.553 |
0.439 |
|
| 2011 |
Graubert T, Walter MJ. Genetics of myelodysplastic syndromes: new insights Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2011: 543-549. PMID 22160087 DOI: 10.1182/Asheducation-2011.1.543 |
0.488 |
|
| 2011 |
Graubert TA, Mardis ER. Genomics of acute myeloid leukemia. Cancer Journal (Sudbury, Mass.). 17: 487-91. PMID 22157292 DOI: 10.1097/Ppo.0B013E31823C5652 |
0.484 |
|
| 2011 |
Welch JS, Westervelt P, Ding L, Larson DE, Klco JM, Kulkarni S, Wallis J, Chen K, Payton JE, Fulton RS, Veizer J, Schmidt H, Vickery TL, Heath S, Watson MA, ... ... Graubert TA, et al. Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. Jama. 305: 1577-84. PMID 21505136 DOI: 10.1001/Jama.2011.497 |
0.672 |
|
| 2011 |
Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, ... ... Graubert TA, et al. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. Jama. 305: 1568-76. PMID 21505135 DOI: 10.1001/Jama.2011.473 |
0.707 |
|
| 2011 |
Wartman LD, Larson DE, Xiang Z, Ding L, Chen K, Lin L, Cahan P, Klco JM, Welch JS, Li C, Payton JE, Uy GL, Varghese N, Ries RE, Hoock M, ... ... Graubert TA, et al. Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression. The Journal of Clinical Investigation. 121: 1445-55. PMID 21436584 DOI: 10.1172/Jci45284 |
0.78 |
|
| 2011 |
Walter MJ, Ding L, Shen D, Shao J, Grillot M, McLellan M, Fulton R, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Kandoth C, Baty J, Westervelt P, Dipersio JF, Mardis ER, ... ... Graubert TA, et al. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes Leukemia. 25: 1153-1158. PMID 21415852 DOI: 10.1182/Blood.V116.21.608.608 |
0.647 |
|
| 2011 |
Welch JS, Larson D, Ding L, McLellan MD, Lamprecht T, Kandoth C, Payton JE, Baty J, Harris CC, Lichti CF, Fulton RS, Dooling DJ, Koboldt DC, Schmidt H, Zhang Q, ... ... Graubert T, et al. Complete Sequencing and Comparison of 12 Normal Karyotype M1 AML Genomes with 12 t(15;17) Positive M3-APL Genomes Blood. 118: 404-404. DOI: 10.1182/Blood.V118.21.404.404 |
0.728 |
|
| 2011 |
Ludwig S, Ivanovich J, Graubert T, Goodfellow P. P2-07-01: Copy Number Variants in Early-Onset-Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P2-07-01 |
0.312 |
|
| 2011 |
Graubert T, Shen D, Ding L, Mardis E, Ley T, Wilson R, Walter M. 242 Genomics of myelodysplastic syndromes Leukemia Research. 35. DOI: 10.1016/S0145-2126(11)70244-2 |
0.503 |
|
| 2010 |
Cahan P, Graubert TA. Integrated genomics of susceptibility to alkylator-induced leukemia in mice. Bmc Genomics. 11: 638. PMID 21080971 DOI: 10.1186/1471-2164-11-638 |
0.676 |
|
| 2010 |
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, ... ... Graubert TA, et al. DNMT3A mutations in acute myeloid leukemia. The New England Journal of Medicine. 363: 2424-33. PMID 21067377 DOI: 10.1056/Nejmoa1005143 |
0.723 |
|
| 2010 |
Higuchi DA, Cahan P, Gao J, Ferris ST, Poursine-Laurent J, Graubert TA, Yokoyama WM. Structural variation of the mouse natural killer gene complex. Genes and Immunity. 11: 637-48. PMID 20861859 DOI: 10.1038/Gene.2010.48 |
0.633 |
|
| 2010 |
Fortier JM, Payton JE, Cahan P, Ley TJ, Walter MJ, Graubert TA. POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature. Leukemia. 24: 950-7. PMID 20376082 DOI: 10.1038/Leu.2010.61 |
0.738 |
|
| 2010 |
Fortier JM, Graubert TA. Murine models of human acute myeloid leukemia. Cancer Treatment and Research. 145: 183-96. PMID 20306252 DOI: 10.1007/978-0-387-69259-3_11 |
0.371 |
|
| 2010 |
Graubert T. Therapy-related myelodysplastic syndrome: models and genetics Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 16: S45-47. PMID 19857585 DOI: 10.1016/J.Bbmt.2009.10.019 |
0.396 |
|
| 2010 |
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch JS, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, ... ... Graubert TA, et al. Mutations In the DNA Methyltransferase Gene DNMT3A Are Highly Recurrent In Patients with Intermediate Risk Acute Myeloid Leukemia, and Predict Poor Outcomes Blood. 116: 99-99. DOI: 10.1182/Blood.V116.21.99.99 |
0.74 |
|
| 2010 |
Schuettpelz L, Link DC, Shen D, Walter MJ, Koboldt DC, Dooling DJ, Fulton RS, Schmidt H, Maupin R, O'Laughlin M, Chen K, McLellan MD, Kulkarni S, Ivanovich J, Lebeau M, ... ... Graubert TA, et al. DNA Sequence of the Cancer Genome of a Patient with Therapy-Related Acute Myeloid Leukemia Blood. 116: 580-580. DOI: 10.1182/Blood.V116.21.580.580 |
0.738 |
|
| 2010 |
Walter MJ, Shen D, Ding L, Shao J, Witowski S, Chen K, Koboldt DC, Dooling DJ, Maupin R, Fulton RS, Schmidt H, O'Laughlin M, McLellan MD, Frater J, Westervelt P, ... ... Graubert T, et al. Detection of Novel Mutations In MDS/AML by Whole Genome Sequencing Blood. 116: 299-299. DOI: 10.1182/Blood.V116.21.299.299 |
0.659 |
|
| 2009 |
Walter MJ, Graubert TA, Dipersio JF, Mardis ER, Wilson RK, Ley TJ. Next-generation sequencing of cancer genomes: back to the future. Personalized Medicine. 6: 653. PMID 20161678 DOI: 10.2217/Pme.09.52 |
0.57 |
|
| 2009 |
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, Koboldt DC, Fulton RS, Delehaunty KD, McGrath SD, Fulton LA, Locke DP, Magrini VJ, Abbott RM, Vickery TL, ... ... Graubert TA, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. The New England Journal of Medicine. 361: 1058-66. PMID 19657110 DOI: 10.1056/Nejmoa0903840 |
0.734 |
|
| 2009 |
Walter MJ, Payton JE, Ries RE, Shannon WD, Deshmukh H, Zhao Y, Baty J, Heath S, Westervelt P, Watson MA, Tomasson MH, Nagarajan R, O'Gara BP, Bloomfield CD, Mrózek K, ... ... Graubert TA, et al. Acquired copy number alterations in adult acute myeloid leukemia genomes. Proceedings of the National Academy of Sciences of the United States of America. 106: 12950-5. PMID 19651600 DOI: 10.1073/Pnas.0903091106 |
0.672 |
|
| 2009 |
Knight JA, Skol AD, Shinde A, Hastings D, Walgren RA, Shao J, Tennant TR, Banerjee M, Allan JM, Le Beau MM, Larson RA, Graubert TA, Cox NJ, Onel K. Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility. Blood. 113: 5575-82. PMID 19299336 DOI: 10.1182/Blood-2008-10-183244 |
0.379 |
|
| 2009 |
Cahan P, Li Y, Izumi M, Graubert TA. The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells. Nature Genetics. 41: 430-7. PMID 19270704 DOI: 10.1038/Ng.350 |
0.669 |
|
| 2009 |
Graubert TA, Payton MA, Shao J, Walgren RA, Monahan RS, Frater JL, Walshauser MA, Martin MG, Kasai Y, Walter MJ. Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis. Plos One. 4: e4583. PMID 19240791 DOI: 10.1371/Journal.Pone.0004583 |
0.411 |
|
| 2009 |
Fortier JM, Payton JE, Cahan P, Ley TJ, Walter MJ, Graubert TA. POU4F1 Is Associated with t(8;21) AML and Contributes Directly to Its Unique Transcriptional Signature. Blood. 114: 2623-2623. DOI: 10.1182/Blood.V114.22.2623.2623 |
0.742 |
|
| 2009 |
Li Y, Cahan P, Izumi M, Graubert T. Caspase-9: A Candidate Susceptibility Factor for Murine Alkylator-Induced Leukemia. Blood. 114: 1273-1273. DOI: 10.1182/Blood.V114.22.1273.1273 |
0.709 |
|
| 2009 |
Martin MG, Jacoby M, Shao J, Deych E, Graubert T, Walter MJ. BRCA1 and BRCA2 Nucleotide Variants in Young Women with Therapy Related Acute Myeloid Leukemia. Blood. 114: 1102-1102. DOI: 10.1182/Blood.V114.22.1102.1102 |
0.435 |
|
| 2008 |
Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH, McGrath S, Hickenbotham M, Cook L, Abbott R, Larson DE, Koboldt DC, Pohl C, ... ... Graubert TA, et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature. 456: 66-72. PMID 18987736 DOI: 10.1038/Nature07485 |
0.732 |
|
| 2008 |
Funk RK, Maxwell TJ, Izumi M, Edwin D, Kreisel F, Ley TJ, Cheverud JM, Graubert TA. Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic mice. Blood. 112: 1434-42. PMID 18552208 DOI: 10.1182/Blood-2008-01-132084 |
0.576 |
|
| 2008 |
Graubert T. AML1 and Evi1: coconspirators in MDS/AML? Blood. 111: 3916-7. PMID 18434965 DOI: 10.1182/blood-2008-01-135376 |
0.302 |
|
| 2008 |
Cahan P, Godfrey LE, Eis PS, Richmond TA, Selzer RR, Brent M, McLeod HL, Ley TJ, Graubert TA. wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data. Nucleic Acids Research. 36: e41. PMID 18334530 DOI: 10.1093/Nar/Gkn110 |
0.687 |
|
| 2008 |
Tomasson MH, Xiang Z, Walgren R, Zhao Y, Kasai Y, Miner T, Ries RE, Lubman O, Fremont DH, McLellan MD, Payton JE, Westervelt P, DiPersio JF, Link DC, Walter MJ, ... Graubert TA, et al. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood. 111: 4797-808. PMID 18270328 DOI: 10.1182/Blood-2007-09-113027 |
0.739 |
|
| 2008 |
Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner TL, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, et al. Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood. 111: 4809-12. PMID 18160671 DOI: 10.1182/Blood-2007-05-090308 |
0.739 |
|
| 2008 |
Onel K, Knight JA, Skol AD, Tennant TR, Banerjee M, Walgren R, Shao J, Allan JM, Beau MML, Larson RA, Graubert T, Cox NJ. A Genome-Wide Analysis to Identify Novel Susceptibility Loci for Therapy-Related Acute Myeloid Leukemia Blood. 112: 432-432. DOI: 10.1182/Blood.V112.11.432.432 |
0.437 |
|
| 2008 |
Janke MR, Babatunde F, Cahan P, Cheverud JM, Graubert TA. MLF1 Is a Candidate Susceptibility Factor for T-AML That Induces Apoptosis in Normal Hematopoietic Cells Blood. 112: 310-310. DOI: 10.1182/Blood.V112.11.310.310 |
0.806 |
|
| 2008 |
Funk R, Cahan P, Izumi M, Graubert T. Bcl2, a Candidate Murine Therapy-Related Acute Myeloid Leukemia Susceptibility Factor, Exhibits Strain-Dependent and Alkylator-Responsive Expression. Blood. 112: 1499-1499. DOI: 10.1182/Blood.V112.11.1499.1499 |
0.655 |
|
| 2008 |
Graubert T. AML1 and Evi1: Coconspirators in MDS/AML? Blood. 111: 3916-3917. DOI: 10.1182/Blood-2008-01-135376 |
0.417 |
|
| 2007 |
Fong T, Trinkaus K, Adkins D, Vij R, Devine SM, Tomasson M, Goodnough LT, Lopez S, Graubert T, Shenoy S, DiPersio JF, Khoury HJ. A Randomized Double-Blind Trial of Hydroxychloroquine for the Prevention of Chronic Graft-versus-Host Disease after Allogeneic Peripheral Blood Stem Cell Transplantation Biology of Blood and Marrow Transplantation. 13: 1201-1206. PMID 17889357 DOI: 10.1016/J.Bbmt.2007.06.012 |
0.328 |
|
| 2007 |
Link DC, Kunter G, Kasai Y, Zhao Y, Miner T, McLellan MD, Ries RE, Kapur D, Nagarajan R, Dale DC, Bolyard AA, Boxer LA, Welte K, Zeidler C, Donadieu J, ... ... Graubert TA, et al. Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia. Blood. 110: 1648-55. PMID 17494858 DOI: 10.1182/Blood-2007-03-081216 |
0.732 |
|
| 2007 |
Graubert TA, Cahan P, Edwin D, Selzer RR, Richmond TA, Eis PS, Shannon WD, Li X, McLeod HL, Cheverud JM, Ley TJ. A high-resolution map of segmental DNA copy number variation in the mouse genome. Plos Genetics. 3: e3. PMID 17206864 DOI: 10.1371/Journal.Pgen.0030003 |
0.709 |
|
| 2007 |
Hake CR, Graubert TA, Fenske TS. Does autologous transplantation directly increase the risk of secondary leukemia in lymphoma patients? Bone Marrow Transplantation. 39: 59-70. PMID 17143301 DOI: 10.1038/Sj.Bmt.1705547 |
0.387 |
|
| 2007 |
Walgren R, Dao C, Kreisel F, Westervelt P, Abboud C, Graubert T, Cashen A, Uy G, Gao F, DiPersio J, Vij R. A Phase II Study of Intravenous Azacitidine Alone in Patients with Myelodysplastic Syndromes NCT00384956. Blood. 110: 1451-1451. DOI: 10.1200/Jco.2008.26.15_Suppl.7097 |
0.317 |
|
| 2007 |
Fehniger TA, Nelson A, Trinkaus K, Abboud CN, Cashen AF, DiPersio JF, Graubert TA, Ley TJ, Tomasson MH, Uy GL, Walter MJ, Westervelt P, Vij R. Phase II Study of High Dose Lenalidomide as Initial Treatment for Older Acute Myeloid Leukemia Patients: Early Results Show a Significant Reduction of Bone Marrow Blasts after 14 Days of Therapy. Blood. 110: 916-916. DOI: 10.1182/Blood.V110.11.916.916 |
0.535 |
|
| 2007 |
Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner T, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, et al. Identification of Novel, Non-Synonymous Sequence Changes in the Tyrosine Kinase Genes of Patients with Acute Myeloid Leukemia. Blood. 110: 823-823. DOI: 10.1182/Blood.V110.11.823.823 |
0.735 |
|
| 2007 |
Ley TJ, DiPersio J, Ding L, Ries R, Magrini V, Payton J, McGrath S, Walter M, Wylie T, Dunford-Shore B, Chen K, McLellan M, Wendl M, Dooling D, Cook L, ... ... Graubert T, et al. Sequencing an Acute Myeloid Leukemia (AML) Genome with “Next Generation” Technologies. Blood. 110: 205-205. DOI: 10.1182/Blood.V110.11.205.205 |
0.718 |
|
| 2007 |
Walgren R, McLaughlin E, Peterson E, Crosswhite M, Province M, McLeod H, Ley T, Graubert T, Morgan G. Identification of Polymorphisms Associated with Susceptibility to Therapy-Related MDS and AML. Blood. 110: 15-15. DOI: 10.1182/Blood.V110.11.15.15 |
0.464 |
|
| 2007 |
Funk RK, Maxwell T, Izumi M, Edwin D, Kreisel F, Cheverud J, Ley TJ, Graubert T. Genetic Susceptibility to Therapy-Related Acute Murine Promyelocytic Leukemia. Blood. 110: 14-14. DOI: 10.1182/Blood.V110.11.14.14 |
0.593 |
|
| 2007 |
Graubert TA, Payton MA, Monahan RS, Shao J, Frater JL, Walgren RA, Kasai Y, Walter MJ. Comprehensive Genomic Copy Number and Sequence Analysis of 28 Chromosome 5q31.2 Candidate Genes in De Novo MDS. Blood. 110: 117-117. DOI: 10.1182/Blood.V110.11.117.117 |
0.484 |
|
| 2007 |
Walter MJ, Ries R, Li X, Shannon W, Payton J, Books J, Bloomfield C, Mrozek K, Ruppert A, DiPersio J, Link D, Tomasson M, Graubert T, Westervelt P, Watson M, et al. High Resolution Array-Based CGH and SNP Studies of AML Genomes. Blood. 110: 107-107. DOI: 10.1182/Blood.V110.11.107.107 |
0.677 |
|
| 2006 |
Knoche E, McLeod HL, Graubert TA. Pharmacogenetics of alkylator-associated acute myeloid leukemia. Pharmacogenomics. 7: 719-29. PMID 16886897 DOI: 10.2217/14622416.7.5.719 |
0.482 |
|
| 2006 |
Fenske TS, McMahon C, Edwin D, Jarvis JC, Cheverud JM, Minn M, Mathews V, Bogue MA, Province MA, McLeod HL, Graubert TA. Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice. Cancer Research. 66: 5029-38. PMID 16707424 DOI: 10.1158/0008-5472.Can-05-3404 |
0.352 |
|
| 2006 |
Gotlib J, George TI, Linder A, Ruddell A, Quesada S, Akin C, DeAngelo DJ, Cohen P, Graubert T. Phase II Trial of the Tyrosine Kinase Inhibitor PKC412 in Advanced Systemic Mastocytosis: Preliminary Results. Blood. 108: 3609-3609. DOI: 10.1182/Blood.V108.11.3609.3609 |
0.31 |
|
| 2005 |
Devine SM, Brown RA, Mathews V, Trinkaus K, Khoury H, Adkins D, Vij R, Sempek D, Graubert T, Tomasson M, Goodnough LT, DiPersio JF. Reduced risk of acute GVHD following mobilization of HLA-identical sibling donors with GM-CSF alone. Bone Marrow Transplantation. 36: 531-8. PMID 16025152 DOI: 10.1038/Sj.Bmt.1705091 |
0.315 |
|
| 2005 |
Fenske TS, Pengue G, Graubert TA. Dominant negative effects of the AML1/ETO fusion oncoprotein. Cell Cycle (Georgetown, Tex.). 4: 33-6. PMID 15611635 DOI: 10.4161/Cc.4.1.1399 |
0.439 |
|
| 2005 |
Edwin D, McMahon C, Kreisel F, Bogue M, Fenske TS, Graubert TA. A Mouse Model of Alkylator-Induced Myelodysplastic Syndrome. Blood. 106: 368-368. DOI: 10.1182/Blood.V106.11.368.368 |
0.464 |
|
| 2005 |
Edwin D, Fenske TS, McMahon C, Mathews V, Bogue M, Province M, Cheverud J, McLeod H, Graubert TA. Susceptibility to Alkylator-Induced Cancer Is a Heritable Trait. Blood. 106: 3266-3266. DOI: 10.1182/Blood.V106.11.3266.3266 |
0.37 |
|
| 2005 |
Walter MJ, Ries RR, Li XD, Shannon WJ, Payton J, Bloomfield CD, Mrozek K, Ruppert AS, DiPersio J, Link D, Tomasson M, Graubert T, McLeod H, Devine S, Watson M, et al. Detection of Microdeletions and Amplifications in Primary Human Acute Myeloid Leukemia (AML) Genomes Using Ultradense Oligomer Tiling Path Arrays and Comparative Genomic Hybridization (CGH). Blood. 106: 2350-2350. DOI: 10.1182/Blood.V106.11.2350.2350 |
0.662 |
|
| 2005 |
Uy G, Fisher N, Devine S, Adkins D, Tomasson M, Graubert T, DiPersio J, Vij R. Bortezomib does not adversely affect stem cell mobilization and engraftment in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation Biology of Blood and Marrow Transplantation. 11: 77. DOI: 10.1016/J.Bbmt.2004.12.228 |
0.331 |
|
| 2004 |
Fenske TS, Pengue G, Mathews V, Hanson PT, Hamm SE, Riaz N, Graubert TA. Stem cell expression of the AML1/ETO fusion protein induces a myeloproliferative disorder in mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 15184-9. PMID 15477599 DOI: 10.1073/Pnas.0400751101 |
0.442 |
|
| 2004 |
Mathews V, Hanson PT, Ford E, Fujita J, Polonsky KS, Graubert TA. Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury. Diabetes. 53: 91-8. PMID 14693702 DOI: 10.2337/Diabetes.53.1.91 |
0.333 |
|
| 2004 |
Uy GL, Fisher NM, Devine SM, Khoury HJ, Adkins DR, Tomasson MH, Graubert TA, DiPersio JF, Vij R. Bortezomib Given in Sequence with Anthracycline and Thalidomide-Containing Regimens Does Not Adversely Affect Stem Cell Mobilization and Engraftment in Patients with Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplantation. Blood. 104: 541-541. DOI: 10.1182/Blood.V104.11.541.541 |
0.354 |
|
| 2003 |
Ley TJ, Minx PJ, Walter MJ, Ries RE, Sun H, McLellan M, DiPersio JF, Link DC, Tomasson MH, Graubert TA, McLeod H, Khoury H, Watson M, Shannon W, Trinkaus K, et al. A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 14275-80. PMID 14614138 DOI: 10.1073/Pnas.2335924100 |
0.728 |
|
| 2003 |
Chohan R, Vij R, Adkins D, Blum W, Brown R, Tomasson M, Devine S, Graubert T, Goodnough LT, DiPersio JF, Khoury H. Long-term outcomes of allogeneic stem cell transplant recipients after calcineurin inhibitor-induced neurotoxicity. British Journal of Haematology. 123: 110-3. PMID 14510951 DOI: 10.1046/J.1365-2141.2003.04550.X |
0.316 |
|
| 2003 |
Watters JW, Kloss EF, Link DC, Graubert TA, McLeod HL. A mouse-based strategy for cyclophosphamide pharmacogenomic discovery. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1352-60. PMID 12970373 DOI: 10.1152/Japplphysiol.00214.2003 |
0.562 |
|
| 2003 |
Hanson P, Mathews V, Marrus SH, Graubert TA. Enhanced green fluorescent protein targeted to the Sca-1 (Ly-6A) locus in transgenic mice results in efficient marking of hematopoietic stem cells in vivo. Experimental Hematology. 31: 159-67. PMID 12591281 DOI: 10.1016/S0301-472X(02)01021-4 |
0.34 |
|
| 2003 |
Rosen J, Welm B, Tepera S, Behbod F, Grimm S, Venezia T, Goodell M, Graubert T, Werb Z, Li Y, Varmus H. Functional characterization of mammary stem cells in development and breast cancer Breast Cancer Research. 5. DOI: 10.1186/Bcr710 |
0.378 |
|
| 2002 |
Welm BE, Tepera SB, Venezia T, Graubert TA, Rosen JM, Goodell MA. Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Developmental Biology. 245: 42-56. PMID 11969254 DOI: 10.1006/Dbio.2002.0625 |
0.332 |
|
| 2000 |
Megan J, Patterson M, Johnson MH, Zimonjic DB, Graubert TA. Characterization of Ly-6M, a novel member of the Ly-6 family of hematopoietic proteins Blood. 95: 3125-3132. PMID 10807778 DOI: 10.1182/Blood.V95.10.3125.010K29_3125_3132 |
0.355 |
|
| 1999 |
Shresta S, Graubert TA, Thomas DA, Raptis SZ, Ley TJ. Granzyme A initiates an alternative pathway for granule-mediated apoptosis. Immunity. 10: 595-605. PMID 10367905 DOI: 10.1016/S1074-7613(00)80059-X |
0.655 |
|
| 1998 |
Shresta S, Pham CT, Thomas DA, Graubert TA, Ley TJ. How do cytotoxic lymphocytes kill their targets? Current Opinion in Immunology. 10: 581-7. PMID 9794837 DOI: 10.1016/S0952-7915(98)80227-6 |
0.646 |
|
| 1998 |
Graubert TA, Hug BA, Wesselschmidt R, Hsieh CL, Ryan TM, Townes TM, Ley TJ. Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene Nucleic Acids Research. 26: 2849-2858. PMID 9611227 DOI: 10.1093/Nar/26.12.2849 |
0.523 |
|
| 1997 |
Graubert TA, DiPersio JF, Russell JH, Ley TJ. Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation Journal of Clinical Investigation. 100: 904-911. PMID 9259590 DOI: 10.1172/Jci119606 |
0.54 |
|
| 1996 |
Graubert TA, Ley TJ. How do lymphocytes kill tumor cells? Clinical Cancer Research. 2: 785-789. PMID 9816231 |
0.415 |
|
| 1996 |
Graubert TA, Russell JH, Ley TJ. The role of granzyme B in murine models of acute graft-versus-host disease and graft rejection Blood. 87: 1232-1237. PMID 8608209 DOI: 10.1182/Blood.V87.4.1232.Bloodjournal8741232 |
0.519 |
|
| 1995 |
Berliner N, Hsing A, Graubert T, Sigurdsson F, Zain M, Bruno E, Hoffman R. Granulocyte colony-stimulating factor induction of normal human bone marrow progenitors results in neutrophil-specific gene expression Blood. 85: 799-803. PMID 7530510 DOI: 10.1182/Blood.V85.3.799.Bloodjournal853799 |
0.373 |
|
| 1993 |
Graubert T, Johnston J, Berliner N. Cloning and expression of the cDNA encoding mouse neutrophil gelatinase: Demonstration of coordinate secondary granule protein gene expression during terminal neutrophil maturation Blood. 82: 3192-3197. PMID 8219207 DOI: 10.1182/Blood.V82.10.3192.3192 |
0.334 |
|
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